ahr1b cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	ahr1b
Entrez Gene ID	554265
Full Name	aryl hydrocarbon receptor 1b
Synonyms	si:dkey-159d6.1
General protein information	Preferred Names aryl hydrocarbon receptor 1b Names aryl hydrocarbon receptor
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001024816.2	NP_001019987.1	aryl hydrocarbon receptor

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	ahr1b	NP_001019987.1
Mus musculus (house mouse)	Ahr	NP_038492.1
Xenopus tropicalis (tropical clawed frog)	ahr	XP_002933348.2
Pan troglodytes (chimpanzee)	AHR	XP_003318385.1
Macaca mulatta (Rhesus monkey)	AHR	XP_001103903.2
Canis lupus familiaris (dog)	AHR	XP_532485.2
Rattus norvegicus (Norway rat)	Ahr	NP_037281.2
Gallus gallus (chicken)	AHR	NP_989449.1
Bos taurus (cattle)	AHR	NP_001192955.1
Homo sapiens (human)	AHR	NP_001612.1

Gene Ontology
Bibliography

Related articles in PubMed

Developmental Regulation of Nuclear Factor Erythroid-2 Related Factors (nrfs) by AHR1b in Zebrafish (Danio rerio).
Ulin A, Henderson J, Pham MT, Meyo J, Chen Y, Karchner SI, Goldstone JV, Hahn ME, Williams LM
Toxicological sciences : an official journal of the Society of Toxicology167(2)536-545(2019 02)

Transcriptomic response and perturbation of toxicity pathways in zebrafish larvae after exposure to graphene quantum dots (GQDs).
Deng S, Jia PP, Zhang JH, Junaid M, Niu A, Ma YB, Fu A, Pei DS
Journal of hazardous materials357146-158(2018 09)

Integrated in silico and in vivo approaches to investigate effects of BDE-99 mediated by the nuclear receptors on developing zebrafish.
Zhang L, Jin Y, Han Z, Liu H, Shi L, Hua X, Doering JA, Tang S, Giesy JP, Yu H
Environmental toxicology and chemistry37(3)780-787(2018 03)

Pharmacokinetics and effects of tetrabromobisphenol a (TBBPA) to early life stages of zebrafish (Danio rerio).
Liu H, Ma Z, Zhang T, Yu N, Su G, Giesy JP, Yu H
Chemosphere190243-252(2018 Jan)

Genetic dissection of endothelial transcriptional activity of zebrafish aryl hydrocarbon receptors (AHRs).
Sugden WW, Leonardo-Mendonça RC, Acuña-Castroviejo D, Siekmann AF
PloS one12(8)e0183433(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ahr1b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ahr1b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa04603	NM_001024816.2 Latest version!	Danio rerio aryl hydrocarbon receptor 1b (ahr1b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ahr1b ( NM_001024816.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001019987.1 Danio rerio aryl hydrocarbon receptor 1b (ahr1b), mRNA.

Price & Availability↑

CloneID	ODa04603
Clone ID Related Accession (Same CDS sequence)	NM_001024816.2
Accession Version	NM_001024816.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2823bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1578067200000
Organism	Danio rerio(zebrafish)
Product	aryl hydrocarbon receptor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX908726.21 and CR394522.8. On Feb 17, 2016 this sequence version replaced NM_001024816.1. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the reference genome strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ016494.1, GFIL01000727.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGTACGCGG GACGAAAAAG AAGAAAACCG GTGCAAAGGA CGGTGAAGCA GCCTCCAGCT 
GAAGGGGTGA AGTCGAACCC GTCCAAACGG CATCGAGATC GGTTAAACTC TGAGTTGGAC 
CGGTTGTCTA GTCTTCTTCC ATTTCCAGAG GAGGTGACGA GCAGCTTGGA CAAACTCTCC 
ATTCTGCGCC TGAGTGTCAG TTACCTGCGC GCCAAGAACT TCTTCTCTGT CACTCTGAAA 
AACCACAACT GCAATGGTTT GTCGTCAAAC AACAGTAACC ACGACAACAG TAAAGCAACA 
GGATTGGTTG ACGGCTGTCT GCGAGAGGGA GAGCTCCTGC TACAGGCTCT TAATGGCTTT 
GTGTTGGTGG TCACAGCCGA GGGGATCATT TTCTACTGTT CTCACACTAT TCAGGATTAC 
TTAGGATTTC ACCAGACGGA TGTAATGCAT CAAAATGTGT TTGAACTCAT TCATACTGAG 
GACCAGCAGG CCTTCAGGCG CAATTTACAC TGGGCCTTGA ACCCGCCGCC AGCCAGCACG 
CAGACAGAAG ACTCATCAGA AGATGGAGAT CCTGCCCCAA ATATGTCTCT TGTGTTGTGC 
AACCCAGACC AGCTGCCTCC CGAAAACTCT TCTTTCCTGG AAAGAAACTT TGTGTGTCGT 
TTCCGATGCC TCCTAGACAA TTCCTCAGGA TTCCTGGCTT TGAATTTTCA AGGACGTCTG 
AAATTCCTGC ATGGGCAAAA CAGGCGATTG GATGATGGAG GCCAAATGCC ACCCCAGCTT 
GCCCTGTTTG CCATTGCGAC GCCCCTACAG CCTCCTTCCA TAATGGAGAT TCGAACCAAG 
AACATGATAT TCAGAACCAA ACACAAGTTG GATTTCACCC CAATGGCCTG CGATGCAAAG 
GGTAAAATAG TTCTTGGCTA CACAGAGGCG GAACTGCGAG TTCGAGGTTC AGGGTACCAG 
TTCATCCATG CAGCTGATAT GCTCTACTGT GCTGAGAACC ATGTCAGGAT GATCAAGACT 
GGAGAGAGTG GTCTGACTGT TTTTAGACTG CTTACAAAGG ACAACCGTTG GAAATGGGTA 
CAAGCTAATG CTAGACTTGT CTACAAAAAT GGCAAGCCTG ACTACATCAT TGCCACCCAG 
AGGCCACTTG TAGAAGAAGA GGGTGGAGAG CACTTGAGGA AACGATCTAT GCATCTTCCA 
TTCACCTTTG CTACTGGAGA AGCTCTGCTG TACCAAATCA ACTACCCCAT GTTGGGCTTC 
CCCGACACCC TTCAGGACAA AGGCAAGAAC AACAAAACCA AAAAGAGCAA GGTGAACAAA 
AGCTCAAAGG ACGATCTGGA TCCAAGTTCC TTACTGGGAG CCATGATGAG ACAGGACGAG 
TCTGTTTATG TTTGCCAGCC AGCTATGGAG CCTAGAATGT CATTCCACAG TAGCCTCTTT 
GGTGAGCAAG GAGAGACTAG CACTTTCTCT TCTTCTGCTG AGAATGAAAG TTGGAATCCA 
GTGCAGAATG GTGTAACTAC AGCCTCCAAA CAGGAGACGT CGAGTTTTGA CCCACTTTTG 
GCAACATTAG ACTCTCTTTC TTTGGAAAAT GAGGAGAGCT GCTCCAACAG TGAGTTATTC 
AGTGCCCTTG AAAATCTTGG ACTCAATGCA GAGGACCTTG AGTTGCTGCT TCTAGATGAA 
AGGATGATCC AGGTAGAAGT GGAACCGGAC TTTATCCCAT CTCTCAATGA TCTTCTCACA 
AACAACGAAA TCCTCTCCTA CGTCCATGAT TCACTGGAGA ACCAGACTGA GGACCCAGCA 
GAGTCTCAAA AGCCTTCAAC TGCATTAGAT TCTGTTGAAA ACTCTAAGCC AGAGTCTGAT 
TCACCTCCTC AAGTAACTTC ATCCGTACCT GCTCCTTTCT GGCCACAAAA ACAGATACCA 
CCCATACTTC ATCTATCACA GCGCATGCAA CAACATCTTA ATGGCCAGTC GGTTTGCCAC 
AAAACTGAGA ACTGGATCCA TACACCATTG TCTCAAGTGC CTACAACAGA ATCTGAGACA 
GCTAACTTTA ACCAGCATGA TACTACTTTG GTGAACTCTG TACCAGTTGT ACACAATGGA 
CACTGGGTCC CTGAACATAC GCAAGTCAAT TTAAACTCTC AACTTAGTGA TAAGATAACA 
GGAACTAGTA AGGCACAGCC ACAGCAATGG CAGCAAAACC AGTTGCCTGT CCCATTCCAG 
TGTAAGCCGA AAACAATTGA GGGTGGAGAT ACCCTTGCAA ATGGGATCTA CAGTAATCCT 
CAGTGGCATG GATACAACTT TGCAGAACAG CTGGTCACAA ATGGACCTTG TTTTCCCAAT 
GGTCAGATGG CACACACTCA GACAATGGGT ACCCATATTA TTGATTACAA CATGACTGAC 
AATTCAGGGG TGGAGTTTAC AATGAACAGC AGTTCATCTG GGAACCTAGG GCAGTTTCAG 
GGAGCTATGG CATCATCTTC GTCCTATCAG CAGGGTTATC AGAAACAGCA GCAGCAGCCA 
AAGGTCACAC CCACTTATTA CGCCTCCTAT ACCAAACAGA ACTCCTCTCT GGAGCATATC 
CTAGGATTAG CCCCACCTTC AAACCTCCCC TCGCTGACGG ATTATGGCTC TGAGTTGACC 
CATGACATGA CCCACAGTAA GATGGAGACC GGTTTTCTTC TGAACTCCAC TAGCGTGACC 
TACAACGGAA GTTGTTTGGT TCCCAATGGC AACACAGTGG CCGCACCTGT CAACAGTCCC 
CACCCACTTC CTGAGCCACA CCCACATCCT CCAGACCCTC AAACCACTGG TTTCTACCTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001019987.1
CDS	468..3290
Translation	MYAGRKRRKPVQRTVKQPPAEGVKSNPSKRHRDRLNSELDRLSSLLPFPEEVTSSLDKLSILRLSVSYLRAKNFFSVTLKNHNCNGLSSNNSNHDNSKATGLVDGCLREGELLLQALNGFVLVVTAEGIIFYCSHTIQDYLGFHQTDVMHQNVFELIHTEDQQAFRRNLHWALNPPPASTQTEDSSEDGDPAPNMSLVLCNPDQLPPENSSFLERNFVCRFRCLLDNSSGFLALNFQGRLKFLHGQNRRLDDGGQMPPQLALFAIATPLQPPSIMEIRTKNMIFRTKHKLDFTPMACDAKGKIVLGYTEAELRVRGSGYQFIHAADMLYCAENHVRMIKTGESGLTVFRLLTKDNRWKWVQANARLVYKNGKPDYIIATQRPLVEEEGGEHLRKRSMHLPFTFATGEALLYQINYPMLGFPDTLQDKGKNNKTKKSKVNKSSKDDLDPSSLLGAMMRQDESVYVCQPAMEPRMSFHSSLFGEQGETSTFSSSAENESWNPVQNGVTTASKQETSSFDPLLATLDSLSLENEESCSNSELFSALENLGLNAEDLELLLLDERMIQVEVEPDFIPSLNDLLTNNEILSYVHDSLENQTEDPAESQKPSTALDSVENSKPESDSPPQVTSSVPAPFWPQKQIPPILHLSQRMQQHLNGQSVCHKTENWIHTPLSQVPTTESETANFNQHDTTLVNSVPVVHNGHWVPEHTQVNLNSQLSDKITGTSKAQPQQWQQNQLPVPFQCKPKTIEGGDTLANGIYSNPQWHGYNFAEQLVTNGPCFPNGQMAHTQTMGTHIIDYNMTDNSGVEFTMNSSSSGNLGQFQGAMASSSSYQQGYQKQQQQPKVTPTYYASYTKQNSSLEHILGLAPPSNLPSLTDYGSELTHDMTHSKMETGFLLNSTSVTYNGSCLVPNGNTVAAPVNSPHPLPEPHPHPPDPQTTGFYL

Target ORF information:

RefSeq Version	NM_001024816.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio aryl hydrocarbon receptor 1b (ahr1b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001024816.2

ORF Insert Sequence:

ATGTACGCGG GACGAAAAAG AAGAAAACCG GTGCAAAGGA CGGTGAAGCA GCCTCCAGCT 
GAAGGGGTGA AGTCGAACCC GTCCAAACGG CATCGAGATC GGTTAAACTC TGAGTTGGAC 
CGGTTGTCTA GTCTTCTTCC ATTTCCAGAG GAGGTGACGA GCAGCTTGGA CAAACTCTCC 
ATTCTGCGCC TGAGTGTCAG TTACCTGCGC GCCAAGAACT TCTTCTCTGT CACTCTGAAA 
AACCACAACT GCAATGGTTT GTCGTCAAAC AACAGTAACC ACGACAACAG TAAAGCAACA 
GGATTGGTTG ACGGCTGTCT GCGAGAGGGA GAGCTCCTGC TACAGGCTCT TAATGGCTTT 
GTGTTGGTGG TCACAGCCGA GGGGATCATT TTCTACTGTT CTCACACTAT TCAGGATTAC 
TTAGGATTTC ACCAGACGGA TGTAATGCAT CAAAATGTGT TTGAACTCAT TCATACTGAG 
GACCAGCAGG CCTTCAGGCG CAATTTACAC TGGGCCTTGA ACCCGCCGCC AGCCAGCACG 
CAGACAGAAG ACTCATCAGA AGATGGAGAT CCTGCCCCAA ATATGTCTCT TGTGTTGTGC 
AACCCAGACC AGCTGCCTCC CGAAAACTCT TCTTTCCTGG AAAGAAACTT TGTGTGTCGT 
TTCCGATGCC TCCTAGACAA TTCCTCAGGA TTCCTGGCTT TGAATTTTCA AGGACGTCTG 
AAATTCCTGC ATGGGCAAAA CAGGCGATTG GATGATGGAG GCCAAATGCC ACCCCAGCTT 
GCCCTGTTTG CCATTGCGAC GCCCCTACAG CCTCCTTCCA TAATGGAGAT TCGAACCAAG 
AACATGATAT TCAGAACCAA ACACAAGTTG GATTTCACCC CAATGGCCTG CGATGCAAAG 
GGTAAAATAG TTCTTGGCTA CACAGAGGCG GAACTGCGAG TTCGAGGTTC AGGGTACCAG 
TTCATCCATG CAGCTGATAT GCTCTACTGT GCTGAGAACC ATGTCAGGAT GATCAAGACT 
GGAGAGAGTG GTCTGACTGT TTTTAGACTG CTTACAAAGG ACAACCGTTG GAAATGGGTA 
CAAGCTAATG CTAGACTTGT CTACAAAAAT GGCAAGCCTG ACTACATCAT TGCCACCCAG 
AGGCCACTTG TAGAAGAAGA GGGTGGAGAG CACTTGAGGA AACGATCTAT GCATCTTCCA 
TTCACCTTTG CTACTGGAGA AGCTCTGCTG TACCAAATCA ACTACCCCAT GTTGGGCTTC 
CCCGACACCC TTCAGGACAA AGGCAAGAAC AACAAAACCA AAAAGAGCAA GGTGAACAAA 
AGCTCAAAGG ACGATCTGGA TCCAAGTTCC TTACTGGGAG CCATGATGAG ACAGGACGAG 
TCTGTTTATG TTTGCCAGCC AGCTATGGAG CCTAGAATGT CATTCCACAG TAGCCTCTTT 
GGTGAGCAAG GAGAGACTAG CACTTTCTCT TCTTCTGCTG AGAATGAAAG TTGGAATCCA 
GTGCAGAATG GTGTAACTAC AGCCTCCAAA CAGGAGACGT CGAGTTTTGA CCCACTTTTG 
GCAACATTAG ACTCTCTTTC TTTGGAAAAT GAGGAGAGCT GCTCCAACAG TGAGTTATTC 
AGTGCCCTTG AAAATCTTGG ACTCAATGCA GAGGACCTTG AGTTGCTGCT TCTAGATGAA 
AGGATGATCC AGGTAGAAGT GGAACCGGAC TTTATCCCAT CTCTCAATGA TCTTCTCACA 
AACAACGAAA TCCTCTCCTA CGTCCATGAT TCACTGGAGA ACCAGACTGA GGACCCAGCA 
GAGTCTCAAA AGCCTTCAAC TGCATTAGAT TCTGTTGAAA ACTCTAAGCC AGAGTCTGAT 
TCACCTCCTC AAGTAACTTC ATCCGTACCT GCTCCTTTCT GGCCACAAAA ACAGATACCA 
CCCATACTTC ATCTATCACA GCGCATGCAA CAACATCTTA ATGGCCAGTC GGTTTGCCAC 
AAAACTGAGA ACTGGATCCA TACACCATTG TCTCAAGTGC CTACAACAGA ATCTGAGACA 
GCTAACTTTA ACCAGCATGA TACTACTTTG GTGAACTCTG TACCAGTTGT ACACAATGGA 
CACTGGGTCC CTGAACATAC GCAAGTCAAT TTAAACTCTC AACTTAGTGA TAAGATAACA 
GGAACTAGTA AGGCACAGCC ACAGCAATGG CAGCAAAACC AGTTGCCTGT CCCATTCCAG 
TGTAAGCCGA AAACAATTGA GGGTGGAGAT ACCCTTGCAA ATGGGATCTA CAGTAATCCT 
CAGTGGCATG GATACAACTT TGCAGAACAG CTGGTCACAA ATGGACCTTG TTTTCCCAAT 
GGTCAGATGG CACACACTCA GACAATGGGT ACCCATATTA TTGATTACAA CATGACTGAC 
AATTCAGGGG TGGAGTTTAC AATGAACAGC AGTTCATCTG GGAACCTAGG GCAGTTTCAG 
GGAGCTATGG CATCATCTTC GTCCTATCAG CAGGGTTATC AGAAACAGCA GCAGCAGCCA 
AAGGTCACAC CCACTTATTA CGCCTCCTAT ACCAAACAGA ACTCCTCTCT GGAGCATATC 
CTAGGATTAG CCCCACCTTC AAACCTCCCC TCGCTGACGG ATTATGGCTC TGAGTTGACC 
CATGACATGA CCCACAGTAA GATGGAGACC GGTTTTCTTC TGAACTCCAC TAGCGTGACC 
TACAACGGAA GTTGTTTGGT TCCCAATGGC AACACAGTGG CCGCACCTGT CAACAGTCCC 
CACCCACTTC CTGAGCCACA CCCACATCCT CCAGACCCTC AAACCACTGG TTTCTACCTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Developmental Regulation of Nuclear Factor Erythroid-2 Related Factors (nrfs) by AHR1b in Zebrafish (Danio rerio).
Toxicological sciences : an official journal of the Society of Toxicology167(2)536-545(2019 02)
Ulin A,Henderson J,Pham MT,Meyo J,Chen Y,Karchner SI,Goldstone JV,Hahn ME,Williams LM

Transcriptomic response and perturbation of toxicity pathways in zebrafish larvae after exposure to graphene quantum dots (GQDs).
Journal of hazardous materials357146-158(2018 09)
Deng S,Jia PP,Zhang JH,Junaid M,Niu A,Ma YB,Fu A,Pei DS

Integrated in silico and in vivo approaches to investigate effects of BDE-99 mediated by the nuclear receptors on developing zebrafish.
Environmental toxicology and chemistry37(3)780-787(2018 03)
Zhang L,Jin Y,Han Z,Liu H,Shi L,Hua X,Doering JA,Tang S,Giesy JP,Yu H

Pharmacokinetics and effects of tetrabromobisphenol a (TBBPA) to early life stages of zebrafish (Danio rerio).
Chemosphere190243-252(2018 Jan)
Liu H,Ma Z,Zhang T,Yu N,Su G,Giesy JP,Yu H

Genetic dissection of endothelial transcriptional activity of zebrafish aryl hydrocarbon receptors (AHRs).
PloS one12(8)e0183433(2017)
Sugden WW,Leonardo-Mendonça RC,Acuña-Castroviejo D,Siekmann AF