pak7 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	pak7
Entrez Gene ID	405898
Full Name	p21 protein (Cdc42/Rac)-activated kinase 7
Synonyms	zgc:76890
General protein information	Preferred Names p21 protein (Cdc42/Rac)-activated kinase 7 Names serine/threonine-protein kinase PAK 7 p21(CDKN1A)-activated kinase 7 pak5 pak6
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_212962.1	NP_998127.1	serine/threonine-protein kinase PAK 7

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	pak7	NP_998127.1
Macaca mulatta (Rhesus monkey)	PAK7	XP_002798252.1
Rattus norvegicus (Norway rat)	Pak7	NP_001101251.1
Gallus gallus (chicken)	PAK7	NP_001186338.1
Caenorhabditis elegans (roundworm)	pak-2	NP_505810.2
Homo sapiens (human)	PAK7	NP_065074.1
Pan troglodytes (chimpanzee)	PAK7	XP_003316835.1
Canis lupus familiaris (dog)	PAK7	XP_542895.2
Bos taurus (cattle)	PAK7	NP_001193523.1
Mus musculus (house mouse)	Pak7	NP_766446.2

Gene Ontology
Bibliography

Related articles in PubMed

Evolution of complexity in the zebrafish synapse proteome.
Bayés À, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 03)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Comparative analysis of the human and zebrafish kinomes: focus on the development of kinase inhibitors.
Wlodarchak N, Tariq R, Striker R
Trends in cell & molecular biology1049-75(2015)

Chronic low-level domoic acid exposure alters gene transcription and impairs mitochondrial function in the CNS.
Hiolski EM, Kendrick PS, Frame ER, Myers MS, Bammler TK, Beyer RP, Farin FM, Wilkerson HW, Smith DR, Marcinek DJ, Lefebvre KA
Aquatic toxicology (Amsterdam, Netherlands)155151-9(2014 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following pak7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the pak7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa02944	NM_212962.1 Latest version!	Danio rerio p21 protein (Cdc42/Rac)-activated kinase 7 (pak7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

pak7 ( NM_212962.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_998127.1 Danio rerio p21 protein (Cdc42/Rac)-activated kinase 7 (pak7), mRNA.

Price & Availability↑

CloneID	ODa02944
Clone ID Related Accession (Same CDS sequence)	NM_212962.1
Accession Version	NM_212962.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2136bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1548432000000
Organism	Danio rerio(zebrafish)
Product	serine/threonine-protein kinase PAK 7
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC068016.1. ##Evidence-Data-START## Transcript exon combination :: BC068016.1 [ECO:0000332] ##Evidence-Data-END##

ATGTTTGGAA AGAAGAAGAA GCGTCTGGAG ATTTCGGCTC CGTCTAACTT CGAGCACCGC 
GTGCACACAG ACTTCGACCC GCAGCAGCAG AAGTTCACCG GCCTGCCGCA GCAATGGCAG 
AGTCTGCTGG CGGACACAGC CAACCGGCCC AAACCCATGG TGGACCCGTC CTACATCACA 
CCCATACAGC TGGCTCCTAT GAAGACTATC GTGCGGGGCA GCAGAGCACC CAGAGACGCC 
TCCATCAACG GCCTGTTGGA GGAGTTCGAC AGCATCTCGG TGTCACGCTC CAACTCTTTG 
CGCAGGGAAA GTCCGGCGGC AGCGGCAGCA GCGGCGGGCA GCAGAGCGCA GAACGGCTTT 
GGGCAGTATG GCCGCTACTC CTGCGATCTG GACAGTGGAG TGTGTGTGGA GGCGGAGTGG 
CAGCGCTCCT CACTGCGGCA AAACGGACAC CCCGGCCTTG GCCCCGGCCC CATCCGTAGC 
CCCTTCTACC CCGACGCCAT GCCGCAGAAG GCCTCGGAGT GGGCCAGGCT GCCGCCGGAT 
TACCATGCGT ACCTGGAGAG CCGGACACAG CTCTGCGGGG AGGGGCCGGT GGGCCGGCGG 
GACTACCGCG CATCTTTGGG CGGCTCCAGC CTGGACTACA GGGACGCTCC GCTGGGCACG 
CCGTCCCGCC TGTCACTCCG CAGCGATCAC ACCAGCTGTC CAGATGCAGA CTGGGGCTTC 
GGTGAGCTCC ACAAGCGGCC CAAATCTTCC TACGGCAGCC ACGGCAGTCC TCAGCCGGCG 
CTCCGGCAGC GCTCACGGTC CGGCTCGGGT CTGCAGGAGC CCAGCAGCAG CAGCGGCAGC 
AGCGGCGCTC CCTACAGCAT CAGTGCGCTC TCTGCAGCAC CACCGCAGGG CTCCTACAGC 
TCTTACACCT ACCCCAGACT CTCCGAAAAC ACCTCCGCTA TGATCATCGG CAAGGCGGAG 
TACGAGCGAG TGTGTCGTGA TGGCAGTCCT CAGGCAGTGT GTGAGCCGTA TCCGCGTGTG 
CCGCTGAAGC TCCCGCACAG TAAAGCTCTG TACCCGCCGG TGCTGCAGTA CCCGCCGCTG 
CTGTGCCAGC CATCCCCGTA CCAGCACCCG CCATCACAGC CCAGCCCGCC CTACACTCCG 
GCGGGCGCAC ATGCACACTC ACACACGCAC TCACAGCCGT CCTCGCCCTA CGTCCCGCCC 
GGGGCCTACC CTCCGCCCAG CTGGGGCTCG CCCGCGGAGC AGCCCCCCCC TCGGGTATCC 
CATGAGCAGT TTCGGGCGGC GCTGCAGCTG GTGGTGGAAC CCGGGGACCC GCGCCAGGGC 
CTGGACAGCT TCCTGAAGAT CGGCGAGGGC TCCACGGGCA TCGTCTGCAT CGCCACCGAG 
AAGCACAGCG GCAAACAGGT GGCGGTCAAG AAGATGGACC TGCGGAAACA GCAGCGGCGC 
GAGCTCCTGT TCAACGAGGT GGTCATCATG AGGGATTACC ATCATGAGAA TGTGGTGGAC 
ATGTACAACA GCTACCTGGT GGGAGACGAG CTCTGGGTCG TCATGGAGTT CCTGGAGGGC 
GGAGCTTTGA CTGACATCGT CACGCACACC AGGATGAATG AGGAACAGAT CGCCACCGTG 
TGTCTGTCAG TCTTGAAGGC GCTCTCATAT CTGCACACTC AGGGCGTCAT TCACAGAGAT 
ATCAAGAGTG ACTCCATCCT ACTGACCAGT GACGGACGGA TCAAACTTTC TGACTTCGGC 
TTCTGTGCTC AAGTGTCTAA AGAGGTTCCC AAGAGGAAGT CCTTAGTGGG GACGCCGTAC 
TGGATGGCTC CGGAGGTCAT CTCCAGGTTA CCCTATGGCA CTGAGGTGGA CATCTGGTCT 
CTGGGCATCA TGGTGATAGA GATGGTGGAT GGAGAACCAC CGTACTTCAA CGAGCCGCCA 
CTGCAGGCCA TGCGAAGAAT ACGAGACAAC CTGCCACCCA GACTCAAGGA GTCTCACAAG 
GTGTCGTCGG TGTTGCGGGC GTTCCTGGAT CTGATGCTGG TGCGAGAGCC GTCCCAGCGG 
GCGTCAGCAC TGGAGCTCCT GCAGAACCCC TTCCTGAAGC TGGCAGGACC CCCGGCCTGC 
ATTGTCCCAC TGATGCGGCA CTACCGGCCC CGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_998127.1
CDS	134..2269
Translation	MFGKKKKRLEISAPSNFEHRVHTDFDPQQQKFTGLPQQWQSLLADTANRPKPMVDPSYITPIQLAPMKTIVRGSRAPRDASINGLLEEFDSISVSRSNSLRRESPAAAAAAAGSRAQNGFGQYGRYSCDLDSGVCVEAEWQRSSLRQNGHPGLGPGPIRSPFYPDAMPQKASEWARLPPDYHAYLESRTQLCGEGPVGRRDYRASLGGSSLDYRDAPLGTPSRLSLRSDHTSCPDADWGFGELHKRPKSSYGSHGSPQPALRQRSRSGSGLQEPSSSSGSSGAPYSISALSAAPPQGSYSSYTYPRLSENTSAMIIGKAEYERVCRDGSPQAVCEPYPRVPLKLPHSKALYPPVLQYPPLLCQPSPYQHPPSQPSPPYTPAGAHAHSHTHSQPSSPYVPPGAYPPPSWGSPAEQPPPRVSHEQFRAALQLVVEPGDPRQGLDSFLKIGEGSTGIVCIATEKHSGKQVAVKKMDLRKQQRRELLFNEVVIMRDYHHENVVDMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIATVCLSVLKALSYLHTQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMVDGEPPYFNEPPLQAMRRIRDNLPPRLKESHKVSSVLRAFLDLMLVREPSQRASALELLQNPFLKLAGPPACIVPLMRHYRPR

Target ORF information:

RefSeq Version	NM_212962.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio p21 protein (Cdc42/Rac)-activated kinase 7 (pak7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_212962.1

ORF Insert Sequence:

ATGTTTGGAA AGAAGAAGAA GCGTCTGGAG ATTTCGGCTC CGTCTAACTT CGAGCACCGC 
GTGCACACAG ACTTCGACCC GCAGCAGCAG AAGTTCACCG GCCTGCCGCA GCAATGGCAG 
AGTCTGCTGG CGGACACAGC CAACCGGCCC AAACCCATGG TGGACCCGTC CTACATCACA 
CCCATACAGC TGGCTCCTAT GAAGACTATC GTGCGGGGCA GCAGAGCACC CAGAGACGCC 
TCCATCAACG GCCTGTTGGA GGAGTTCGAC AGCATCTCGG TGTCACGCTC CAACTCTTTG 
CGCAGGGAAA GTCCGGCGGC AGCGGCAGCA GCGGCGGGCA GCAGAGCGCA GAACGGCTTT 
GGGCAGTATG GCCGCTACTC CTGCGATCTG GACAGTGGAG TGTGTGTGGA GGCGGAGTGG 
CAGCGCTCCT CACTGCGGCA AAACGGACAC CCCGGCCTTG GCCCCGGCCC CATCCGTAGC 
CCCTTCTACC CCGACGCCAT GCCGCAGAAG GCCTCGGAGT GGGCCAGGCT GCCGCCGGAT 
TACCATGCGT ACCTGGAGAG CCGGACACAG CTCTGCGGGG AGGGGCCGGT GGGCCGGCGG 
GACTACCGCG CATCTTTGGG CGGCTCCAGC CTGGACTACA GGGACGCTCC GCTGGGCACG 
CCGTCCCGCC TGTCACTCCG CAGCGATCAC ACCAGCTGTC CAGATGCAGA CTGGGGCTTC 
GGTGAGCTCC ACAAGCGGCC CAAATCTTCC TACGGCAGCC ACGGCAGTCC TCAGCCGGCG 
CTCCGGCAGC GCTCACGGTC CGGCTCGGGT CTGCAGGAGC CCAGCAGCAG CAGCGGCAGC 
AGCGGCGCTC CCTACAGCAT CAGTGCGCTC TCTGCAGCAC CACCGCAGGG CTCCTACAGC 
TCTTACACCT ACCCCAGACT CTCCGAAAAC ACCTCCGCTA TGATCATCGG CAAGGCGGAG 
TACGAGCGAG TGTGTCGTGA TGGCAGTCCT CAGGCAGTGT GTGAGCCGTA TCCGCGTGTG 
CCGCTGAAGC TCCCGCACAG TAAAGCTCTG TACCCGCCGG TGCTGCAGTA CCCGCCGCTG 
CTGTGCCAGC CATCCCCGTA CCAGCACCCG CCATCACAGC CCAGCCCGCC CTACACTCCG 
GCGGGCGCAC ATGCACACTC ACACACGCAC TCACAGCCGT CCTCGCCCTA CGTCCCGCCC 
GGGGCCTACC CTCCGCCCAG CTGGGGCTCG CCCGCGGAGC AGCCCCCCCC TCGGGTATCC 
CATGAGCAGT TTCGGGCGGC GCTGCAGCTG GTGGTGGAAC CCGGGGACCC GCGCCAGGGC 
CTGGACAGCT TCCTGAAGAT CGGCGAGGGC TCCACGGGCA TCGTCTGCAT CGCCACCGAG 
AAGCACAGCG GCAAACAGGT GGCGGTCAAG AAGATGGACC TGCGGAAACA GCAGCGGCGC 
GAGCTCCTGT TCAACGAGGT GGTCATCATG AGGGATTACC ATCATGAGAA TGTGGTGGAC 
ATGTACAACA GCTACCTGGT GGGAGACGAG CTCTGGGTCG TCATGGAGTT CCTGGAGGGC 
GGAGCTTTGA CTGACATCGT CACGCACACC AGGATGAATG AGGAACAGAT CGCCACCGTG 
TGTCTGTCAG TCTTGAAGGC GCTCTCATAT CTGCACACTC AGGGCGTCAT TCACAGAGAT 
ATCAAGAGTG ACTCCATCCT ACTGACCAGT GACGGACGGA TCAAACTTTC TGACTTCGGC 
TTCTGTGCTC AAGTGTCTAA AGAGGTTCCC AAGAGGAAGT CCTTAGTGGG GACGCCGTAC 
TGGATGGCTC CGGAGGTCAT CTCCAGGTTA CCCTATGGCA CTGAGGTGGA CATCTGGTCT 
CTGGGCATCA TGGTGATAGA GATGGTGGAT GGAGAACCAC CGTACTTCAA CGAGCCGCCA 
CTGCAGGCCA TGCGAAGAAT ACGAGACAAC CTGCCACCCA GACTCAAGGA GTCTCACAAG 
GTGTCGTCGG TGTTGCGGGC GTTCCTGGAT CTGATGCTGG TGCGAGAGCC GTCCCAGCGG 
GCGTCAGCAC TGGAGCTCCT GCAGAACCCC TTCCTGAAGC TGGCAGGACC CCCGGCCTGC 
ATTGTCCCAC TGATGCGGCA CTACCGGCCC CGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 03)
Bayés À,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Comparative analysis of the human and zebrafish kinomes: focus on the development of kinase inhibitors.
Trends in cell & molecular biology1049-75(2015)
Wlodarchak N,Tariq R,Striker R

Chronic low-level domoic acid exposure alters gene transcription and impairs mitochondrial function in the CNS.
Aquatic toxicology (Amsterdam, Netherlands)155151-9(2014 Oct)
Hiolski EM,Kendrick PS,Frame ER,Myers MS,Bammler TK,Beyer RP,Farin FM,Wilkerson HW,Smith DR,Marcinek DJ,Lefebvre KA

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pak7 cDNA ORF clone, Danio rerio(zebrafish)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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