KCNH1 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	KCNH1
Entrez Gene ID	281881
Full Name	potassium voltage-gated channel subfamily H member 1
Synonyms	EAG,bEAG
General protein information	Preferred Names potassium voltage-gated channel subfamily H member 1 Names potassium voltage-gated channel subfamily H member 1 ether-a-go-go potassium channel 1 potassium channel, voltage gated eag related subfamily H, member 1 potassium voltage-gated channel, subfamily H (eag-related), member 1 voltage-gated potassium channel subunit Kv10.1
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_174372.2	NP_776797.1	potassium voltage-gated channel subfamily H member 1
XM_024976030.1	XP_024831798.1	potassium voltage-gated channel subfamily H member 1 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Kcnh1	NP_113930.1
Xenopus tropicalis (tropical clawed frog)	kcnh1	XP_002934755.2
Canis lupus familiaris (dog)	LOC490277	XP_005623012.1
Mus musculus (house mouse)	Kcnh1	NP_001033696.1
Gallus gallus (chicken)	KCNH1	XP_419440.4
Homo sapiens (human)	KCNH1	NP_758872.1
Pan troglodytes (chimpanzee)	KCNH1	XP_001169423.2
Macaca mulatta (Rhesus monkey)	KCNH1	XP_001109251.1
Danio rerio (zebrafish)	kcnh1b	NP_001265743.1
Bos taurus (cattle)	KCNH1	NP_776797.1
Oryza sativa (rice)	Os01g0756700	NP_001044290.1
Danio rerio (zebrafish)	kcnh1a	NP_001038396.1

Gene Ontology
Bibliography

Related articles in PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Marçais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Characterization of ether-à-go-go channels present in photoreceptors reveals similarity to IKx, a K+ current in rod inner segments.
Frings S, Brüll N, Dzeja C, Angele A, Hagen V, Kaupp UB, Baumann A
The Journal of general physiology111(4)583-99(1998 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following KCNH1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KCNH1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa42816	NM_174372.2 Latest version!	Bos taurus potassium voltage-gated channel subfamily H member 1 (KCNH1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OBa223418	XM_024976030.1 Latest version!	Bos taurus potassium voltage-gated channel subfamily H member 1 (KCNH1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KCNH1 ( NM_174372.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776797.1 Bos taurus potassium voltage-gated channel subfamily H member 1 (KCNH1), mRNA.

Price & Availability↑

CloneID	OBa42816
Clone ID Related Accession (Same CDS sequence)	NM_174372.2
Accession Version	NM_174372.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2964bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571414400000
Organism	Bos taurus(cattle)
Product	potassium voltage-gated channel subfamily H member 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from Y13431.1. On or before Mar 29, 2005 this sequence version replaced XM_601022.1, NM_174372.1. ##Evidence-Data-START## Transcript exon combination :: Y13431.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145419, SAMN03145425 [ECO:0000348] ##Evidence-Data-END##

ATGACCATGG CTGGGGGCAG GAAGGGACTG GTGGCCCCGC AAAACACGTT TCTGGAGAAT 
ATTGTCCGGC GGTCCAATGA TACTAACTTT GTTTTGGGGA ATGCCCAGAT AGTGGACTGG 
CCTATCGTGT ACAGCAATGA TGGATTTTGC AAGCTGTCTG GCTATCACAG GGCGGAAGTG 
ATGCAAAAAA GCAGTACATG CAGTTTTATG TATGGGGAGC TGACCGATAA AGATACCATT 
GAAAAAGTGC GGCAAACCTT TGAGAACTAT GAGATGAATT CCTTTGAAAT TCTGATGTAC 
AAGAAGAACA GGACACCTGT GTGGTTCTTT GTGAAAATTG CTCCAATTCG AAACGAACAG 
GATAAAGTGG TTTTATTTCT TTGCACTTTC AGTGACATAA CCGCTTTCAA ACAGCCGATT 
GAAGATGATT CATGTAAAGG CTGGGGGAAG TTCGCTCGGC TGACCAGAGC ACTGACGAGC 
AGCCGGGGTG TCCTGCAGCA GCTGGCTCCC AGCGTGCAGA AAGGCGAGAA CGTCCACAAG 
CACTCCCGTC TGGCCGAGGT TCTGCAGCTG GGCTCAGACA TCCTTCCCCA GTACAAGCAA 
GAGGCACCAA AGACTCCCCC GCACATCATC TTACACTACT GCGTTTTTAA GACCACGTGG 
GACTGGATCA TCCTGATCCT AACCTTCTAC ACAGCCATCC TGGTTCCTTA CAACGTCTCC 
TTTAAAACCA GGCAGAACAA CGTGGCCTGG CTGGTTGTGG ACAGCATCGT GGATGTCATT 
TTTTTGGTGG ACATTGTGCT GAATTTTCAC ACCACTTTTG TTGGACCCGC TGGGGAGGTG 
ATTTCTGACC CCAAACTCAT TCGCATGAAC TACCTGAAGA CGTGGTTTGT GATTGACCTT 
CTGTCCTGTT TGCCCTATGA CGTCATCAAC GCTTTTGAGA ACGTGGATGA GGTTAGTGCC 
TTTATGGGTG ATCCAGGGAA GATTGGTTTT GCTGATCAGA TTCCACCACC CCTGGAGGGG 
AGAGAGAGTC AGGGCATCAG CAGCCTGTTC AGCTCTCTGA AAGTTGTCCG GCTGCTCCGC 
CTGGGACGCG TGGCCCGGAA GCTGGACCAC TACATCGAGT ATGGAGCTGC CGTGCTGGTC 
CTGCTGGTGT GTGTGTTCGG GCTGGCCGCT CACTGGATGG CCTGCATTTG GTACAGCATC 
GGGGACTATG AGATCTTCGA CGAGGACACC AAGACCATCC GCAACAACAG CTGGCTCTAC 
CAGCTGGCCA TGGACATTGG CACCCCTTAC CAGTTTAACG GGTCTGGCTC AGGGAAGTGG 
GAAGGGGGTC CCAGCAAGAA TTCCGTCTAC ATCTCCTCGT TGTATTTCAC CATGACCAGC 
CTCACCAGCG TGGGCTTTGG GAACATCGCC CCGTCCACAG ACATTGAGAA GATCTTTGCC 
GTGGCCATCA TGATGATTGG CTCCCTCCTC TATGCCACCA TCTTTGGGAA TGTGACGACC 
ATTTTCCAAC AGATGTACGC CAACACCAAC AGGTACCATG AGATGCTCAA CAGTGTCCGG 
GACTTCTTGA AGCTCTACCA GGTGCCCAAG GGGCTGAGCG AGCGAGTCAT GGATTACATC 
GTGTCCACCT GGTCCATGTC CAGAGGCATT GACACAGAGA AGGTCCTGCA GATCTGCCCC 
AAGGACATGA GAGCGGACAT CTGCGTGCAC CTAAACCGCA AGGTCTTCAA GGAGCACCCA 
GCCTTTCGGC TGGCCAGCGA CGGCTGCCTG CGGGCACTGG CCATGGAGTT CCAGACGGTG 
CACTGCGCCC CTGGGGACCT CATCTACCAC GCAGGGGAGA GCGTCGACAG CCTGTGCTTC 
GTGGTCTCCG GCTCCCTGGA GGTGATCCAG GATGACGAGG TGGTGGCCAT TCTAGGGAAA 
GGAGACGTGT TTGGAGACGT GTTCTGGAAG GAAGCCACCC TTGCCCAGTC CTGTGCCAAT 
GTGAGGGCCT TGACCTACTG TGACCTCCAT GTGATCAAGC GGGACGCCCT GCAGAAAGTG 
CTGGAATTCT ACACAGCCTT CTCCCACTCC TTCTCCCGGA ACCTCATTCT CACCTACAAC 
TTGAGGAAGC GGATCGTGTT CCGGAAGATC AGTGACGTGA AACGGGAGGA GGAGGAGCGC 
ATGAAGCGGA AGAATGAGGC CCCCCTGATC CTGCCGCCCG ACCACCCCGT CCGGCGGCTC 
TTCCAGAGGT TCCGCCAGCA GAAGGAAGCC AGGCTGGCCG CGGAGAGGGG CGGGCGGGAC 
TTGGACGACC TGGACGTGGA GAAGGGCAGC GTCCTCACCG AGCACAGCCA CCACGGCCTG 
GCGAAGGCCA GCGTCGTCAC CGTCCGAGAG AGCCCTGCCA CGCCCGTGGC CTTCCCGGCG 
GCCGCTGCCC CGGCGGGGCT GGATCACGCC CGGCTGCAGG CGCCTGGGGC CGAGGGCCTG 
GGCCCCAAGG CCGGCGGGGC CGACTGCGCC AAGCGCAAGG GCTGGGCCCG CTTCAAGGAT 
GCCTGCGGGC AGGCTGAGGA CTGGAGCAAG GTGTCCAAGG CCGAGTCCAT GGAAACGCTC 
CCCGAGAGGA CGAAGGCCGC CGGCGAGGCC ACACTCAAGA AGACGGACTC GTGCGACAGC 
GGCATCACCA AGAGCGACCT GCGTCTGGAC AACGTGGGCG AGGCCAGAAG CCCCCAGGAC 
CGGAGCCCCA TCTTGGCGGA GGTCAAGCAC TCCTTCTACC CCATCCCCGA GCAGACGCTG 
CAGGCCGCCG TCCTGGAGGT GAAGCACGAG CTCAAGGAGG ACATCAAGGC CTTGAGCACC 
AAGATGACGA GCATTGAGAA ACAGCTCTCT GAGATACTCA GGATATTAAC CTCCAGAAGA 
TCCTCTCAGT CGCCTCAGGA GCTATTTGAA ATATCGAGGC CCCAGTCCCC AGAGTCAGAG 
AGAGACATTT TTGGCGCAAG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776797.1
CDS	198..3161
Translation	MTMAGGRKGLVAPQNTFLENIVRRSNDTNFVLGNAQIVDWPIVYSNDGFCKLSGYHRAEVMQKSSTCSFMYGELTDKDTIEKVRQTFENYEMNSFEILMYKKNRTPVWFFVKIAPIRNEQDKVVLFLCTFSDITAFKQPIEDDSCKGWGKFARLTRALTSSRGVLQQLAPSVQKGENVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCVFKTTWDWIILILTFYTAILVPYNVSFKTRQNNVAWLVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVINAFENVDEVSAFMGDPGKIGFADQIPPPLEGRESQGISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWMACIWYSIGDYEIFDEDTKTIRNNSWLYQLAMDIGTPYQFNGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDDEVVAILGKGDVFGDVFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFYTAFSHSFSRNLILTYNLRKRIVFRKISDVKREEEERMKRKNEAPLILPPDHPVRRLFQRFRQQKEARLAAERGGRDLDDLDVEKGSVLTEHSHHGLAKASVVTVRESPATPVAFPAAAAPAGLDHARLQAPGAEGLGPKAGGADCAKRKGWARFKDACGQAEDWSKVSKAESMETLPERTKAAGEATLKKTDSCDSGITKSDLRLDNVGEARSPQDRSPILAEVKHSFYPIPEQTLQAAVLEVKHELKEDIKALSTKMTSIEKQLSEILRILTSRRSSQSPQELFEISRPQSPESERDIFGAS

Target ORF information:

RefSeq Version	NM_174372.2
Organism	Bos taurus(cattle)
Definition	Bos taurus potassium voltage-gated channel subfamily H member 1 (KCNH1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174372.2

ORF Insert Sequence:

ATGACCATGG CTGGGGGCAG GAAGGGACTG GTGGCCCCGC AAAACACGTT TCTGGAGAAT 
ATTGTCCGGC GGTCCAATGA TACTAACTTT GTTTTGGGGA ATGCCCAGAT AGTGGACTGG 
CCTATCGTGT ACAGCAATGA TGGATTTTGC AAGCTGTCTG GCTATCACAG GGCGGAAGTG 
ATGCAAAAAA GCAGTACATG CAGTTTTATG TATGGGGAGC TGACCGATAA AGATACCATT 
GAAAAAGTGC GGCAAACCTT TGAGAACTAT GAGATGAATT CCTTTGAAAT TCTGATGTAC 
AAGAAGAACA GGACACCTGT GTGGTTCTTT GTGAAAATTG CTCCAATTCG AAACGAACAG 
GATAAAGTGG TTTTATTTCT TTGCACTTTC AGTGACATAA CCGCTTTCAA ACAGCCGATT 
GAAGATGATT CATGTAAAGG CTGGGGGAAG TTCGCTCGGC TGACCAGAGC ACTGACGAGC 
AGCCGGGGTG TCCTGCAGCA GCTGGCTCCC AGCGTGCAGA AAGGCGAGAA CGTCCACAAG 
CACTCCCGTC TGGCCGAGGT TCTGCAGCTG GGCTCAGACA TCCTTCCCCA GTACAAGCAA 
GAGGCACCAA AGACTCCCCC GCACATCATC TTACACTACT GCGTTTTTAA GACCACGTGG 
GACTGGATCA TCCTGATCCT AACCTTCTAC ACAGCCATCC TGGTTCCTTA CAACGTCTCC 
TTTAAAACCA GGCAGAACAA CGTGGCCTGG CTGGTTGTGG ACAGCATCGT GGATGTCATT 
TTTTTGGTGG ACATTGTGCT GAATTTTCAC ACCACTTTTG TTGGACCCGC TGGGGAGGTG 
ATTTCTGACC CCAAACTCAT TCGCATGAAC TACCTGAAGA CGTGGTTTGT GATTGACCTT 
CTGTCCTGTT TGCCCTATGA CGTCATCAAC GCTTTTGAGA ACGTGGATGA GGTTAGTGCC 
TTTATGGGTG ATCCAGGGAA GATTGGTTTT GCTGATCAGA TTCCACCACC CCTGGAGGGG 
AGAGAGAGTC AGGGCATCAG CAGCCTGTTC AGCTCTCTGA AAGTTGTCCG GCTGCTCCGC 
CTGGGACGCG TGGCCCGGAA GCTGGACCAC TACATCGAGT ATGGAGCTGC CGTGCTGGTC 
CTGCTGGTGT GTGTGTTCGG GCTGGCCGCT CACTGGATGG CCTGCATTTG GTACAGCATC 
GGGGACTATG AGATCTTCGA CGAGGACACC AAGACCATCC GCAACAACAG CTGGCTCTAC 
CAGCTGGCCA TGGACATTGG CACCCCTTAC CAGTTTAACG GGTCTGGCTC AGGGAAGTGG 
GAAGGGGGTC CCAGCAAGAA TTCCGTCTAC ATCTCCTCGT TGTATTTCAC CATGACCAGC 
CTCACCAGCG TGGGCTTTGG GAACATCGCC CCGTCCACAG ACATTGAGAA GATCTTTGCC 
GTGGCCATCA TGATGATTGG CTCCCTCCTC TATGCCACCA TCTTTGGGAA TGTGACGACC 
ATTTTCCAAC AGATGTACGC CAACACCAAC AGGTACCATG AGATGCTCAA CAGTGTCCGG 
GACTTCTTGA AGCTCTACCA GGTGCCCAAG GGGCTGAGCG AGCGAGTCAT GGATTACATC 
GTGTCCACCT GGTCCATGTC CAGAGGCATT GACACAGAGA AGGTCCTGCA GATCTGCCCC 
AAGGACATGA GAGCGGACAT CTGCGTGCAC CTAAACCGCA AGGTCTTCAA GGAGCACCCA 
GCCTTTCGGC TGGCCAGCGA CGGCTGCCTG CGGGCACTGG CCATGGAGTT CCAGACGGTG 
CACTGCGCCC CTGGGGACCT CATCTACCAC GCAGGGGAGA GCGTCGACAG CCTGTGCTTC 
GTGGTCTCCG GCTCCCTGGA GGTGATCCAG GATGACGAGG TGGTGGCCAT TCTAGGGAAA 
GGAGACGTGT TTGGAGACGT GTTCTGGAAG GAAGCCACCC TTGCCCAGTC CTGTGCCAAT 
GTGAGGGCCT TGACCTACTG TGACCTCCAT GTGATCAAGC GGGACGCCCT GCAGAAAGTG 
CTGGAATTCT ACACAGCCTT CTCCCACTCC TTCTCCCGGA ACCTCATTCT CACCTACAAC 
TTGAGGAAGC GGATCGTGTT CCGGAAGATC AGTGACGTGA AACGGGAGGA GGAGGAGCGC 
ATGAAGCGGA AGAATGAGGC CCCCCTGATC CTGCCGCCCG ACCACCCCGT CCGGCGGCTC 
TTCCAGAGGT TCCGCCAGCA GAAGGAAGCC AGGCTGGCCG CGGAGAGGGG CGGGCGGGAC 
TTGGACGACC TGGACGTGGA GAAGGGCAGC GTCCTCACCG AGCACAGCCA CCACGGCCTG 
GCGAAGGCCA GCGTCGTCAC CGTCCGAGAG AGCCCTGCCA CGCCCGTGGC CTTCCCGGCG 
GCCGCTGCCC CGGCGGGGCT GGATCACGCC CGGCTGCAGG CGCCTGGGGC CGAGGGCCTG 
GGCCCCAAGG CCGGCGGGGC CGACTGCGCC AAGCGCAAGG GCTGGGCCCG CTTCAAGGAT 
GCCTGCGGGC AGGCTGAGGA CTGGAGCAAG GTGTCCAAGG CCGAGTCCAT GGAAACGCTC 
CCCGAGAGGA CGAAGGCCGC CGGCGAGGCC ACACTCAAGA AGACGGACTC GTGCGACAGC 
GGCATCACCA AGAGCGACCT GCGTCTGGAC AACGTGGGCG AGGCCAGAAG CCCCCAGGAC 
CGGAGCCCCA TCTTGGCGGA GGTCAAGCAC TCCTTCTACC CCATCCCCGA GCAGACGCTG 
CAGGCCGCCG TCCTGGAGGT GAAGCACGAG CTCAAGGAGG ACATCAAGGC CTTGAGCACC 
AAGATGACGA GCATTGAGAA ACAGCTCTCT GAGATACTCA GGATATTAAC CTCCAGAAGA 
TCCTCTCAGT CGCCTCAGGA GCTATTTGAA ATATCGAGGC CCCAGTCCCC AGAGTCAGAG 
AGAGACATTT TTGGCGCAAG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KCNH1 ( XM_024976030.1 ) cDNA ORF clone, Bos taurus(cattle) -> XP_024831798.1 Bos taurus potassium voltage-gated channel subfamily H member 1 (KCNH1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa223418
Clone ID Related Accession (Same CDS sequence)	XM_024976030.1
Accession Version	XM_024976030.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2883bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1525536000000
Organism	Bos taurus(cattle)
Product	potassium voltage-gated channel subfamily H member 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037343.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCATGG CTGGGGGCAG GAAGGGACTG GTGGCCCCGC AAAACACGTT TCTGGAGAAT 
ATTGTCCGGC GGTCCAATGA TACTAACTTT GTGTTGGGGA ATGCCCAGAT AGTGGACTGG 
CCTATCGTGT ACAGCAATGA TGGATTTTGC AAGCTGTCTG GCTATCACAG GGCGGAAGTG 
ATGCAAAAAA GCAGTACATG CAGTTTTATG TATGGGGAGC TGACCGATAA AGATACCATT 
GAAAAAGTGC GGCAAACCTT TGAGAACTAT GAGATGAATT CCTTTGAAAT TCTGATGTAC 
AAGAAGAACA GGACACCTGT GTGGTTCTTT GTGAAAATTG CTCCAATTCG AAACGAACAG 
GATAAAGTGG TTTTATTTCT TTGCACTTTC AGTGACATAA CCGCTTTCAA ACAGCCGATT 
GAAGATGATT CATGTAAAGG CTGGGGGAAG TTCGCTCGGC TGACCAGAGC ACTGACGAGC 
AGCCGGGGTG TCCTGCAGCA GCTGGCTCCC AGCGTGCAGA AAGGCGAGAA CGTCCACAAG 
CACTCCCGTC TGGCCGAGGT TCTGCAGCTG GGCTCAGACA TCCTTCCCCA GTACAAGCAA 
GAGGCACCAA AGACTCCCCC GCACATCATC TTACACTACT GCGTTTTTAA GACCACGTGG 
GACTGGATCA TCCTGATCCT AACCTTCTAC ACAGCCATCC TGGTTCCTTA CAACGTCTCC 
TTTAAAACCA GGCAGAACAA CGTGGCCTGG CTGGTTGTGG ACAGCATCGT GGATGTCATT 
TTTTTGGTGG ACATTGTGCT GAATTTTCAC ACCACTTTTG TTGGACCCGC TGGGGAGGTG 
ATTTCTGACC CCAAACTCAT TCGCATGAAC TACCTGAAGA CGTGGTTTGT GATTGACCTT 
CTGTCCTGTT TGCCCTATGA CGTCATCAAC GCTTTTGAGA ACGTGGATGA GGGCATCAGC 
AGCCTGTTCA GCTCTCTGAA AGTCGTCCGG CTGCTCCGCC TGGGACGGGT GGCCCGGAAG 
CTGGACCACT ACATCGAGTA TGGAGCTGCC GTGCTGGTGC TGCTGGTGTG TGTGTTCGGG 
CTGGCCGCTC ACTGGATGGC CTGCATTTGG TACAGCATCG GGGACTATGA GATCTTCGAC 
GAGGACACCA AGACCATCCG CAACAACAGC TGGCTCTACC AGCTGGCCAT GGACATTGGC 
ACCCCTTACC AGTTTAACGG GTCTGGCTCA GGGAAGTGGG AAGGGGGTCC CAGCAAGAAT 
TCCGTCTACA TCTCCTCGTT GTATTTCACC ATGACCAGCC TCACCAGCGT GGGCTTTGGG 
AACATTGCCC CGTCCACAGA CATTGAGAAG ATCTTTGCCG TGGCCATCAT GATGATTGGC 
TCCCTCCTCT ATGCCACCAT CTTTGGGAAT GTGACGACCA TTTTCCAACA GATGTACGCC 
AACACCAACA GGTACCATGA GATGCTCAAC AGTGTCCGGG ACTTCTTGAA GCTCTACCAG 
GTGCCCAAGG GGCTGAGCGA GCGAGTCATG GATTACATCG TGTCCACCTG GTCCATGTCC 
AGAGGCATTG ACACAGAGAA GGTCCTGCAG ATCTGCCCCA AGGACATGAG AGCGGACATC 
TGCGTGCACC TAAACCGCAA GGTCTTCAAG GAGCACCCAG CCTTTCGGCT GGCCAGCGAC 
GGCTGCCTGC GGGCACTGGC CATGGAGTTC CAGACGGTGC ACTGCGCCCC TGGGGACCTC 
ATCTACCACG CAGGGGAGAG CGTCGACAGC CTGTGCTTCG TGGTCTCCGG CTCCCTGGAG 
GTGATCCAGG ATGACGAGGT GGTGGCCATT CTAGGGAAAG GAGACGTGTT TGGAGACGTG 
TTCTGGAAGG AAGCCACCCT TGCCCAGTCC TGTGCCAATG TGAGGGCCTT GACCTACTGT 
GACCTCCATG TGATCAAGCG GGACGCCCTG CAGAAAGTGC TGGAATTCTA CACAGCCTTC 
TCCCACTCCT TCTCCCGGAA CCTCATTCTC ACCTACAACT TGAGGAAGCG GATCGTGTTC 
CGGAAGATCA GTGACGTGAA ACGGGAGGAG GAGGAGCGCA TGAAGCGGAA GAATGAGGCC 
CCCCTGATCC TGCCGCCCGA CCACCCCGTC CGGCGGCTCT TCCAGAGGTT CCGCCAGCAG 
AAGGAAGCCA GGCTGGCCGC GGAGAGGGGC GGGCGGGACT TGGACGACCT GGACGTGGAG 
AAGGGCAGCG TCCTCACCGA GCACAGCCAC CACGGCCTGG CGAAGGCCAG CGTCGTCACC 
GTCCGAGAGA GCCCTGCCAC GCCCGTGGCC TTCCCGGCGG CCGCCGCCCC GGCGGGGCTG 
GATCACGCCC GGCTGCAGGC GCCTGGGGCC GAGGGCCTGG GCCCCAAGGC CGGCGGGGCC 
GACTGCGCCA AGCGCAAGGG CTGGGCCCGC TTCAAGGATG CCTGCGGGCA GGCTGAGGAC 
TGGAGCAAGG TGTCCAAGGC CGAGTCCATG GAAACGCTCC CCGAGAGGAC GAAGGCCGCC 
GGCGAGGCCA CACTCAAGAA GACGGACTCG TGCGACAGCG GCATCACCAA GAGCGACCTG 
CGTCTGGACA ACGTGGGCGA GGCCAGAAGC CCCCAGGACC GGAGCCCCAT CTTGGCGGAG 
GTCAAGCACT CCTTCTACCC CATCCCCGAG CAGACGCTGC AGGCCGCCGT CCTGGAGGTG 
AAGCACGAGC TCAAGGAGGA CATCAAGGCC TTGAGCACCA AGATGACGAG CATTGAGAAA 
CAGCTCTCTG AGATACTCAG GATATTAACC TCCAGAAGAT CCTCTCAGTC GCCTCAGGAG 
CTATTTGAAA TATCGAGGCC CCAGTCCCCA GAGTCAGAGA GAGACATTTT TGGCGCAAGC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024831798.1
CDS	183..3065
Translation	MTMAGGRKGLVAPQNTFLENIVRRSNDTNFVLGNAQIVDWPIVYSNDGFCKLSGYHRAEVMQKSSTCSFMYGELTDKDTIEKVRQTFENYEMNSFEILMYKKNRTPVWFFVKIAPIRNEQDKVVLFLCTFSDITAFKQPIEDDSCKGWGKFARLTRALTSSRGVLQQLAPSVQKGENVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCVFKTTWDWIILILTFYTAILVPYNVSFKTRQNNVAWLVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVINAFENVDEGISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWMACIWYSIGDYEIFDEDTKTIRNNSWLYQLAMDIGTPYQFNGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDDEVVAILGKGDVFGDVFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFYTAFSHSFSRNLILTYNLRKRIVFRKISDVKREEEERMKRKNEAPLILPPDHPVRRLFQRFRQQKEARLAAERGGRDLDDLDVEKGSVLTEHSHHGLAKASVVTVRESPATPVAFPAAAAPAGLDHARLQAPGAEGLGPKAGGADCAKRKGWARFKDACGQAEDWSKVSKAESMETLPERTKAAGEATLKKTDSCDSGITKSDLRLDNVGEARSPQDRSPILAEVKHSFYPIPEQTLQAAVLEVKHELKEDIKALSTKMTSIEKQLSEILRILTSRRSSQSPQELFEISRPQSPESERDIFGAS

Target ORF information:

RefSeq Version	XM_024976030.1
Organism	Bos taurus(cattle)
Definition	Bos taurus potassium voltage-gated channel subfamily H member 1 (KCNH1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024976030.1

ORF Insert Sequence:

ATGACCATGG CTGGGGGCAG GAAGGGACTG GTGGCCCCGC AAAACACGTT TCTGGAGAAT 
ATTGTCCGGC GGTCCAATGA TACTAACTTT GTGTTGGGGA ATGCCCAGAT AGTGGACTGG 
CCTATCGTGT ACAGCAATGA TGGATTTTGC AAGCTGTCTG GCTATCACAG GGCGGAAGTG 
ATGCAAAAAA GCAGTACATG CAGTTTTATG TATGGGGAGC TGACCGATAA AGATACCATT 
GAAAAAGTGC GGCAAACCTT TGAGAACTAT GAGATGAATT CCTTTGAAAT TCTGATGTAC 
AAGAAGAACA GGACACCTGT GTGGTTCTTT GTGAAAATTG CTCCAATTCG AAACGAACAG 
GATAAAGTGG TTTTATTTCT TTGCACTTTC AGTGACATAA CCGCTTTCAA ACAGCCGATT 
GAAGATGATT CATGTAAAGG CTGGGGGAAG TTCGCTCGGC TGACCAGAGC ACTGACGAGC 
AGCCGGGGTG TCCTGCAGCA GCTGGCTCCC AGCGTGCAGA AAGGCGAGAA CGTCCACAAG 
CACTCCCGTC TGGCCGAGGT TCTGCAGCTG GGCTCAGACA TCCTTCCCCA GTACAAGCAA 
GAGGCACCAA AGACTCCCCC GCACATCATC TTACACTACT GCGTTTTTAA GACCACGTGG 
GACTGGATCA TCCTGATCCT AACCTTCTAC ACAGCCATCC TGGTTCCTTA CAACGTCTCC 
TTTAAAACCA GGCAGAACAA CGTGGCCTGG CTGGTTGTGG ACAGCATCGT GGATGTCATT 
TTTTTGGTGG ACATTGTGCT GAATTTTCAC ACCACTTTTG TTGGACCCGC TGGGGAGGTG 
ATTTCTGACC CCAAACTCAT TCGCATGAAC TACCTGAAGA CGTGGTTTGT GATTGACCTT 
CTGTCCTGTT TGCCCTATGA CGTCATCAAC GCTTTTGAGA ACGTGGATGA GGGCATCAGC 
AGCCTGTTCA GCTCTCTGAA AGTCGTCCGG CTGCTCCGCC TGGGACGGGT GGCCCGGAAG 
CTGGACCACT ACATCGAGTA TGGAGCTGCC GTGCTGGTGC TGCTGGTGTG TGTGTTCGGG 
CTGGCCGCTC ACTGGATGGC CTGCATTTGG TACAGCATCG GGGACTATGA GATCTTCGAC 
GAGGACACCA AGACCATCCG CAACAACAGC TGGCTCTACC AGCTGGCCAT GGACATTGGC 
ACCCCTTACC AGTTTAACGG GTCTGGCTCA GGGAAGTGGG AAGGGGGTCC CAGCAAGAAT 
TCCGTCTACA TCTCCTCGTT GTATTTCACC ATGACCAGCC TCACCAGCGT GGGCTTTGGG 
AACATTGCCC CGTCCACAGA CATTGAGAAG ATCTTTGCCG TGGCCATCAT GATGATTGGC 
TCCCTCCTCT ATGCCACCAT CTTTGGGAAT GTGACGACCA TTTTCCAACA GATGTACGCC 
AACACCAACA GGTACCATGA GATGCTCAAC AGTGTCCGGG ACTTCTTGAA GCTCTACCAG 
GTGCCCAAGG GGCTGAGCGA GCGAGTCATG GATTACATCG TGTCCACCTG GTCCATGTCC 
AGAGGCATTG ACACAGAGAA GGTCCTGCAG ATCTGCCCCA AGGACATGAG AGCGGACATC 
TGCGTGCACC TAAACCGCAA GGTCTTCAAG GAGCACCCAG CCTTTCGGCT GGCCAGCGAC 
GGCTGCCTGC GGGCACTGGC CATGGAGTTC CAGACGGTGC ACTGCGCCCC TGGGGACCTC 
ATCTACCACG CAGGGGAGAG CGTCGACAGC CTGTGCTTCG TGGTCTCCGG CTCCCTGGAG 
GTGATCCAGG ATGACGAGGT GGTGGCCATT CTAGGGAAAG GAGACGTGTT TGGAGACGTG 
TTCTGGAAGG AAGCCACCCT TGCCCAGTCC TGTGCCAATG TGAGGGCCTT GACCTACTGT 
GACCTCCATG TGATCAAGCG GGACGCCCTG CAGAAAGTGC TGGAATTCTA CACAGCCTTC 
TCCCACTCCT TCTCCCGGAA CCTCATTCTC ACCTACAACT TGAGGAAGCG GATCGTGTTC 
CGGAAGATCA GTGACGTGAA ACGGGAGGAG GAGGAGCGCA TGAAGCGGAA GAATGAGGCC 
CCCCTGATCC TGCCGCCCGA CCACCCCGTC CGGCGGCTCT TCCAGAGGTT CCGCCAGCAG 
AAGGAAGCCA GGCTGGCCGC GGAGAGGGGC GGGCGGGACT TGGACGACCT GGACGTGGAG 
AAGGGCAGCG TCCTCACCGA GCACAGCCAC CACGGCCTGG CGAAGGCCAG CGTCGTCACC 
GTCCGAGAGA GCCCTGCCAC GCCCGTGGCC TTCCCGGCGG CCGCCGCCCC GGCGGGGCTG 
GATCACGCCC GGCTGCAGGC GCCTGGGGCC GAGGGCCTGG GCCCCAAGGC CGGCGGGGCC 
GACTGCGCCA AGCGCAAGGG CTGGGCCCGC TTCAAGGATG CCTGCGGGCA GGCTGAGGAC 
TGGAGCAAGG TGTCCAAGGC CGAGTCCATG GAAACGCTCC CCGAGAGGAC GAAGGCCGCC 
GGCGAGGCCA CACTCAAGAA GACGGACTCG TGCGACAGCG GCATCACCAA GAGCGACCTG 
CGTCTGGACA ACGTGGGCGA GGCCAGAAGC CCCCAGGACC GGAGCCCCAT CTTGGCGGAG 
GTCAAGCACT CCTTCTACCC CATCCCCGAG CAGACGCTGC AGGCCGCCGT CCTGGAGGTG 
AAGCACGAGC TCAAGGAGGA CATCAAGGCC TTGAGCACCA AGATGACGAG CATTGAGAAA 
CAGCTCTCTG AGATACTCAG GATATTAACC TCCAGAAGAT CCTCTCAGTC GCCTCAGGAG 
CTATTTGAAA TATCGAGGCC CCAGTCCCCA GAGTCAGAGA GAGACATTTT TGGCGCAAGC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Marçais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Characterization of ether-à-go-go channels present in photoreceptors reveals similarity to IKx, a K+ current in rod inner segments.
The Journal of general physiology111(4)583-99(1998 Apr)
Frings S,Brüll N,Dzeja C,Angele A,Hagen V,Kaupp UB,Baumann A

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KCNH1 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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