COMP cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	COMP
Entrez Gene ID	281088
Full Name	cartilage oligomeric matrix protein
General protein information	Preferred Names cartilage oligomeric matrix protein Names cartilage oligomeric matrix protein
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001166517.1	NP_001159989.1	cartilage oligomeric matrix protein precursor
NM_001166517.2	NP_001159989.2	cartilage oligomeric matrix protein precursor

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	COMP	XP_001115565.1
Canis lupus familiaris (dog)	COMP	XP_533869.2
Gallus gallus (chicken)	COMP	XP_418238.2
Homo sapiens (human)	COMP	NP_000086.2
Danio rerio (zebrafish)	im:7154332	XP_002663752.3
Rattus norvegicus (Norway rat)	Comp	NP_036966.1
Drosophila melanogaster (fruit fly)	Tsp	NP_523495.2
Xenopus tropicalis (tropical clawed frog)	comp	XP_002940251.2
Pan troglodytes (chimpanzee)	COMP	NP_001092035.1
Bos taurus (cattle)	COMP	NP_001159989.1
Mus musculus (house mouse)	Comp	NP_057894.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002157	XP_308033.5

Gene Ontology
Bibliography

Related articles in PubMed

Differential response of cartilage oligomeric matrix protein (COMP) to morphogens of bone morphogenetic protein/transforming growth factor-β family in the surface, middle and deep zones of articular cartilage.
Motaung SC, Di Cesare PE, Reddi AH
Journal of tissue engineering and regenerative medicine5(6)e87-96(2011 Jun)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Marçais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

COMP acts as a catalyst in collagen fibrillogenesis.
Halász K, Kassner A, Mörgelin M, Heinegård D
The Journal of biological chemistry282(43)31166-73(2007 Oct)

Expression of PSACH-associated mutant COMP in tendon fibroblasts leads to increased apoptotic cell death irrespective of the secretory characteristics of mutant COMP.
Weirich C, Keene DR, Kirsch K, Heil M, Neumann E, Dinser R
Matrix biology : journal of the International Society for Matrix Biology26(4)314-23(2007 May)

Effects of simple and complex motion patterns on gene expression of chondrocytes seeded in 3D scaffolds.
Grad S, Gogolewski S, Alini M, Wimmer MA
Tissue engineering12(11)3171-9(2006 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following COMP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the COMP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa239184	NM_001166517.2 Latest version!	Bos taurus cartilage oligomeric matrix protein (COMP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OBa44504	NM_001166517.1 Latest version!	Bos taurus cartilage oligomeric matrix protein (COMP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

COMP ( NM_001166517.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001159989.2 Bos taurus cartilage oligomeric matrix protein (COMP), mRNA.

Price & Availability↑

CloneID	OBa239184
Clone ID Related Accession (Same CDS sequence)	NM_001166517.2
Accession Version	NM_001166517.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2271bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577635200000
Organism	Bos taurus(cattle)
Product	cartilage oligomeric matrix protein precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from NKLS02000007.1. On May 30, 2018 this sequence version replaced NM_001166517.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN03145415, SAMN03145418 [ECO:0000348] ##Evidence-Data-END##

ATGGTTCTCG CCGCCGCCCG CGTTCTCTTG CTCACGCTGG CTGCCCTCGG GGCATCAGGC 
CAGGGGCAGA TGCCGCTGGG TGGGGACCTG GGCCCGCAGA TGCTACGCGA ACTCCAGGAG 
ACCAACGCGG CCCTGCAGGA CGTACGGGAC CTACTGCGGC AGCAGGTCAA GGAGATTACG 
TTCCTGAAAA ACACGGTGAT GGAGTGTGAC GCGTGCGGGA TGCAACCCGC GCGAACCCCC 
AAACTGACGG TACGGCCGCT AAGCCAGTGT TCGCCCGGCT TCTGCTTCCC CGGAGTGGCT 
TGTACCGAGA CAGCCAACGG CGCGCGCTGC GGACCCTGCC CCGAAGGTTT CACAGGCAAC 
GGCTCGCACT GCGCCGACGT CAACGAGTGC ACTGCCCATC CTTGCTTCCC TCGCGTTCGC 
TGCATCAATA CCAGTCCGGG CTTCCGCTGC GAGGCTTGCC CACCTGGGTT CAGCGGCCCC 
ACCCATGAGG GCGTGGGGCT GGCCTTCGCC AAGGCCAACA AGCAGGTTTG TACGGACATT 
AACGAGTGTG AGACCGGGCA GCATAACTGC GTCCCCAACT CTGTATGCGT CAATACCGTG 
GGCTCCTTCC AGTGTGGCCC TTGCCAGCCC GGCTTCGTGG GCGACCAGGC ATCAGGCTGC 
CGTCGGCGGC CACAGCGCTT CTGCCCTGAC GGCACGCCCA GCCCGTGCCA CGAGAAGGCC 
GACTGCGTCC TAGAGCGTGA TGGGTCGCGA TCTTGCGTGT GCGCCGTCGG CTGGGCTGGC 
AATGGGCTCA TCTGCGGCCG CGACACAGAC TTAGACGGCT TTCCGGACGA GAAGCTACGC 
TGCTCTGAGC GCCAGTGCAG AAAGGACAAC TGCGTGACGG TGCCCAACTC AGGGCAGGAG 
GATGTGGACC AGGACGGCAT CGGAGACGCC TGCGACCCGG ACGCCGACGG GGACGGCGTC 
CTCAATGAGA AGGACAACTG CCCGCTCGTG CGGAACCCAG ACCAGCGAAA TACGGATGGC 
GACAAGTGGG GCGATGCGTG CGACAACTGT CGGTCCCAGA AGAACGACGA CCAGAAGGAC 
ACAGATAAGG ACGGCCGAGG CGACGCCTGC GACGACGACA TAGACGGCGA CCGGATCCGC 
AATCCGGTGG ACAACTGCCC CAAGGTGCCC AACTCAGATC AGAAAGACAC TGATGGTGAT 
GGTGTAGGAG ATGCCTGTGA CAACTGTCCT CAGAAGAGCA ACGCAGACCA GAGGGATGTG 
GACCACGACT TCGTGGGAGA TGCTTGTGAC AGCGACCAAG ACCAGGATGG GGATGGGCAC 
CAGGACTCGA AGGACAACTG CCCTACAGTG CCCAACAGTG CCCAGCAGGA CTCAGACCAC 
GATGGCCAGG GTGACGCCTG CGACGACGAT GACGACAATG ATGGGGTCCC CGACAGTAGG 
GACAACTGCC GTCTAGTGCC CAACCCGGGC CAGGAAGACA TGGACCGCGA CGGCGTGGGT 
GACGCGTGCC AGGGCGACTT TGATGCGGAC AAGGTGGTAG ACAAGATCGA TGTGTGTCCG 
GAGAACGCTG AGGTCACACT CACCGACTTC CGGGCCTTCC AGACGGTCGT GCTGGACCCT 
GAGGGCGACG CACAGATAGA CCCTAACTGG GTGGTGCTCA ACCAGGGTAT GGAGATCGTA 
CAGACGATGA ACAGCGACCC AGGCCTGGCT GTGGGTTACA CGGCCTTCAA TGGCGTGGAT 
TTCGAAGGCA CGTTCCACGT GAACACTGCC ACGGATGACG ACTACGCTGG TTTCATCTTT 
GGCTACCAGG ACAGCTCCAG CTTCTATGTG GTCATGTGGA AGCAGATGGA GCAGACGTAC 
TGGCAGGCGA ACCCCTTCCG TGCGGTGGCA GAGCCCGGCA TCCAGCTCAA GGCCGTGAAG 
TCCTCCACAG GCCCTGGGGA GCAGCTTCGG AACGCACTGT GGCACACAGG GGACACAGCG 
TCACAGGTGC GGCTGCTGTG GAAGGATCCC CGGAACGTGG GCTGGAAGGA CAAGACATCC 
TACCGCTGGT TCCTGCAGCA CCGGCCCCAA GTGGGCTATA TTAGAGTGCG ATTCTACGAG 
GGCCCAGAGC TGGTGGCAGA CAGCAACGTG ATCCTGGATA CGACCATGCG GGGCGGTCGT 
CTGGGGGTCT TCTGCTTCTC CCAGGAGAAC ATCATCTGGG CCAACCTGCG CTACCGCTGC 
AACGACACCA TCCCCGAGGA CTACGAGGCC CAGAGGCTGC TGCAGGCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159989.2
CDS	28..2298
Translation	MVLAAARVLLLTLAALGASGQGQMPLGGDLGPQMLRELQETNAALQDVRDLLRQQVKEITFLKNTVMECDACGMQPARTPKLTVRPLSQCSPGFCFPGVACTETANGARCGPCPEGFTGNGSHCADVNECTAHPCFPRVRCINTSPGFRCEACPPGFSGPTHEGVGLAFAKANKQVCTDINECETGQHNCVPNSVCVNTVGSFQCGPCQPGFVGDQASGCRRRPQRFCPDGTPSPCHEKADCVLERDGSRSCVCAVGWAGNGLICGRDTDLDGFPDEKLRCSERQCRKDNCVTVPNSGQEDVDQDGIGDACDPDADGDGVLNEKDNCPLVRNPDQRNTDGDKWGDACDNCRSQKNDDQKDTDKDGRGDACDDDIDGDRIRNPVDNCPKVPNSDQKDTDGDGVGDACDNCPQKSNADQRDVDHDFVGDACDSDQDQDGDGHQDSKDNCPTVPNSAQQDSDHDGQGDACDDDDDNDGVPDSRDNCRLVPNPGQEDMDRDGVGDACQGDFDADKVVDKIDVCPENAEVTLTDFRAFQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTATDDDYAGFIFGYQDSSSFYVVMWKQMEQTYWQANPFRAVAEPGIQLKAVKSSTGPGEQLRNALWHTGDTASQVRLLWKDPRNVGWKDKTSYRWFLQHRPQVGYIRVRFYEGPELVADSNVILDTTMRGGRLGVFCFSQENIIWANLRYRCNDTIPEDYEAQRLLQA

Target ORF information:

RefSeq Version	NM_001166517.2
Organism	Bos taurus(cattle)
Definition	Bos taurus cartilage oligomeric matrix protein (COMP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166517.2

ORF Insert Sequence:

ATGGTTCTCG CCGCCGCCCG CGTTCTCTTG CTCACGCTGG CTGCCCTCGG GGCATCAGGC 
CAGGGGCAGA TGCCGCTGGG TGGGGACCTG GGCCCGCAGA TGCTACGCGA ACTCCAGGAG 
ACCAACGCGG CCCTGCAGGA CGTACGGGAC CTACTGCGGC AGCAGGTCAA GGAGATTACG 
TTCCTGAAAA ACACGGTGAT GGAGTGTGAC GCGTGCGGGA TGCAACCCGC GCGAACCCCC 
AAACTGACGG TACGGCCGCT AAGCCAGTGT TCGCCCGGCT TCTGCTTCCC CGGAGTGGCT 
TGTACCGAGA CAGCCAACGG CGCGCGCTGC GGACCCTGCC CCGAAGGTTT CACAGGCAAC 
GGCTCGCACT GCGCCGACGT CAACGAGTGC ACTGCCCATC CTTGCTTCCC TCGCGTTCGC 
TGCATCAATA CCAGTCCGGG CTTCCGCTGC GAGGCTTGCC CACCTGGGTT CAGCGGCCCC 
ACCCATGAGG GCGTGGGGCT GGCCTTCGCC AAGGCCAACA AGCAGGTTTG TACGGACATT 
AACGAGTGTG AGACCGGGCA GCATAACTGC GTCCCCAACT CTGTATGCGT CAATACCGTG 
GGCTCCTTCC AGTGTGGCCC TTGCCAGCCC GGCTTCGTGG GCGACCAGGC ATCAGGCTGC 
CGTCGGCGGC CACAGCGCTT CTGCCCTGAC GGCACGCCCA GCCCGTGCCA CGAGAAGGCC 
GACTGCGTCC TAGAGCGTGA TGGGTCGCGA TCTTGCGTGT GCGCCGTCGG CTGGGCTGGC 
AATGGGCTCA TCTGCGGCCG CGACACAGAC TTAGACGGCT TTCCGGACGA GAAGCTACGC 
TGCTCTGAGC GCCAGTGCAG AAAGGACAAC TGCGTGACGG TGCCCAACTC AGGGCAGGAG 
GATGTGGACC AGGACGGCAT CGGAGACGCC TGCGACCCGG ACGCCGACGG GGACGGCGTC 
CTCAATGAGA AGGACAACTG CCCGCTCGTG CGGAACCCAG ACCAGCGAAA TACGGATGGC 
GACAAGTGGG GCGATGCGTG CGACAACTGT CGGTCCCAGA AGAACGACGA CCAGAAGGAC 
ACAGATAAGG ACGGCCGAGG CGACGCCTGC GACGACGACA TAGACGGCGA CCGGATCCGC 
AATCCGGTGG ACAACTGCCC CAAGGTGCCC AACTCAGATC AGAAAGACAC TGATGGTGAT 
GGTGTAGGAG ATGCCTGTGA CAACTGTCCT CAGAAGAGCA ACGCAGACCA GAGGGATGTG 
GACCACGACT TCGTGGGAGA TGCTTGTGAC AGCGACCAAG ACCAGGATGG GGATGGGCAC 
CAGGACTCGA AGGACAACTG CCCTACAGTG CCCAACAGTG CCCAGCAGGA CTCAGACCAC 
GATGGCCAGG GTGACGCCTG CGACGACGAT GACGACAATG ATGGGGTCCC CGACAGTAGG 
GACAACTGCC GTCTAGTGCC CAACCCGGGC CAGGAAGACA TGGACCGCGA CGGCGTGGGT 
GACGCGTGCC AGGGCGACTT TGATGCGGAC AAGGTGGTAG ACAAGATCGA TGTGTGTCCG 
GAGAACGCTG AGGTCACACT CACCGACTTC CGGGCCTTCC AGACGGTCGT GCTGGACCCT 
GAGGGCGACG CACAGATAGA CCCTAACTGG GTGGTGCTCA ACCAGGGTAT GGAGATCGTA 
CAGACGATGA ACAGCGACCC AGGCCTGGCT GTGGGTTACA CGGCCTTCAA TGGCGTGGAT 
TTCGAAGGCA CGTTCCACGT GAACACTGCC ACGGATGACG ACTACGCTGG TTTCATCTTT 
GGCTACCAGG ACAGCTCCAG CTTCTATGTG GTCATGTGGA AGCAGATGGA GCAGACGTAC 
TGGCAGGCGA ACCCCTTCCG TGCGGTGGCA GAGCCCGGCA TCCAGCTCAA GGCCGTGAAG 
TCCTCCACAG GCCCTGGGGA GCAGCTTCGG AACGCACTGT GGCACACAGG GGACACAGCG 
TCACAGGTGC GGCTGCTGTG GAAGGATCCC CGGAACGTGG GCTGGAAGGA CAAGACATCC 
TACCGCTGGT TCCTGCAGCA CCGGCCCCAA GTGGGCTATA TTAGAGTGCG ATTCTACGAG 
GGCCCAGAGC TGGTGGCAGA CAGCAACGTG ATCCTGGATA CGACCATGCG GGGCGGTCGT 
CTGGGGGTCT TCTGCTTCTC CCAGGAGAAC ATCATCTGGG CCAACCTGCG CTACCGCTGC 
AACGACACCA TCCCCGAGGA CTACGAGGCC CAGAGGCTGC TGCAGGCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COMP ( NM_001166517.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001159989.1 Bos taurus cartilage oligomeric matrix protein (COMP), mRNA.

Price & Availability↑

CloneID	OBa44504
Clone ID Related Accession (Same CDS sequence)	NM_001166517.1
Accession Version	NM_001166517.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2271bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1420214400000
Organism	Bos taurus(cattle)
Product	cartilage oligomeric matrix protein precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AAFC03073993.1 and AAFC03073995.1. On Oct 27, 2009 this sequence version replaced XM_591255.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN01093729, SAMN01093733 [ECO:0000350] ##Evidence-Data-END##

ATGGTTCTCG CCGCCGCCCG CGTTCTCTTG CTCACGCTGG CTGCCCTCGG GGCATCAGGC 
CAGGGGCAGA TGCCGCTGGG TGGGGACCTG GGCCCGCAGA TGCTACGCGA ACTCCAGGAG 
ACCAACGCGG CCCTGCAGGA CGTACGGGAC CTACTGCGGC AGCAGGTCAA GGAGATTACG 
TTCCTGAAAA ACACGGTGAT GGAGTGTGAC GCGTGCGGGA TGCAACCCGC GCGAACCCCC 
AAACTGACGG TACGGCCGCT AAGCCAGTGT TCGCCCGGCT TCTGCTTCCC CGGAGTGGCT 
TGTACCGAGA CAGCCAACGG CGCGCGCTGC GGACCCTGCC CCGAAGGTTT CACAGGCAAC 
GGCTCGCACT GCGCCGACGT CAACGAGTGC ACTGCCCATC CTTGCTTCCC TCGCGTTCGC 
TGCATCAATA CCAGTCCGGG CTTCCGCTGC GAGGCTTGCC CACCTGGGTT CAGCGGCCCC 
ACCCATGAGG GCGTGGGGCT GGCCTTCGCC AAGGCCAACA AGCAGGTTTG TACGGACATT 
AACGAGTGTG AGACCGGGCA GCATAACTGC GTCCCCAACT CTGTATGCGT CAATACCGTG 
GGCTCCTTCC AGTGTGGCCC TTGCCAGCCC GGCTTCGTGG GCGACCAGGC ATCAGGCTGC 
CGTCGGCGGC CACAGCGCTT CTGCCCTGAC GGCACGCCCA GCCCGTGCCA CGAGAAGGCC 
GACTGCGTCC TAGAGCGTGA TGGGTCGCGA TCTTGCGTGT GCGCCGTCGG CTGGGCTGGC 
AATGGGCTCA TCTGCGGCCG CGACACAGAC TTAGACGGCT TTCCGGACGA GAAGCTACGC 
TGCTCTGAGC GCCAGTGCAG AAAGGACAAC TGCGTGACGG TGCCCAACTC AGGGCAGGAG 
GATGTGGACC AGGACGGCAT CGGAGACGCC TGCGACCCGG ACGCCGACGG GGACGGCGTC 
CTCAATGAGA AGGACAACTG CCCGCTCGTG CGGAACCCAG ACCAGCGAAA TACGGATGGC 
GACAAGTGGG GCGATGCGTG CGACAACTGT CGGTCCCAGA AGAACGACGA CCAGAATGAC 
ACAGATAAGG ACGGCCGAGG CGACGCCTGC GACGACGACA TACACGGCGA CCGGATCCGC 
AATCCGGTGG ACAACTGCCC CAAGGTGCCC AACTCAGATC AGAAAGACAC TGATGGTGAT 
GGTGTAGGAG ATGCCTGTGA CAACTGTCCT CAGAAGAGCA ACGCAGACCA GAGGGATGTG 
GACCACGACT TCGTGGGAGA TGCTTGTGAC AGCGACCAAG ACCAGGATGG GGATGGGCAC 
CAGGACTCGA AGGACAACTG CCCTACAGTG CCCAACAGTG CCCAGCAGGA CTCAGACCAC 
GATGGCCAGG GTGACGCCTG CGACGACGAT GACGACAATG ATGGGGTCCC CGACAGTAGG 
GACAACTGCC GTCTAGTGCC CAACCCGGGC CAGGAAGACA TGGACCGCGA CGGCGTGGGT 
GACGCGTGCC AGGGCGACTT TGATGCGGAC AAGGTGGTAG ACAAGATCGA TGTGTGTCCG 
GAGAACGCTG AGGTCACACT CACCGACTTC CGGGCCTTCC AGACGGTCGT GCTGGACCCT 
GAGGGCGACG CACAGATAGA CCCTAACTGG GTGGTGCTCA ACCAGGGTAT GGAGATCGTA 
CAGACGATGA ACAGCGACCC AGGCCTGGCT GTGGGTTACA CGGCCTTCAA TGGCGTGGAT 
TTCGAAGGCA CGTTCCACGT GAACACTGCC ACGGATGACG ACTACGCTGG TTTCATCTTT 
GGCTACCAGG ACAGCTCCAG CTTCTATGTG GTCATGTGGA AGCAGATGGA GCAGACGTAC 
TGGCAGGCGA ACCCCTTCCG TGCGGTGGCA GAGCCCGGCA TCCAGCTCAA GGCCGTGAAG 
TCCTCCACAG GCCCTGGGGA GCAGCTTCGG AACGCACTGT GGCACACAGG GGACACAGCG 
TCACAGGTGC GGCTGCTGTG GAAGGATCCC CGGAACGTGG GCTGGAAGGA CAAGACATCC 
TACCGCTGGT TCCTGCAGCA CCGGCCCCAA GTGGGCTATA TTAGAGTGCG ATTCTACGAG 
GGCCCAGAGC TGGTGGCAGA CAGCAACGTG ATCCTGGATA CGACCATGCG GGGCGGTCGT 
CTGGGGGTCT TCTGCTTCTC CCAGGAGAAC ATCATCTGGG CCAACCTGCG CTACCGCTGC 
AACGACACCA TCCCCGAGGA CTACGAGGCC CAGAGGCTGC TGCAGGCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159989.1
CDS	28..2298
Translation	MVLAAARVLLLTLAALGASGQGQMPLGGDLGPQMLRELQETNAALQDVRDLLRQQVKEITFLKNTVMECDACGMQPARTPKLTVRPLSQCSPGFCFPGVACTETANGARCGPCPEGFTGNGSHCADVNECTAHPCFPRVRCINTSPGFRCEACPPGFSGPTHEGVGLAFAKANKQVCTDINECETGQHNCVPNSVCVNTVGSFQCGPCQPGFVGDQASGCRRRPQRFCPDGTPSPCHEKADCVLERDGSRSCVCAVGWAGNGLICGRDTDLDGFPDEKLRCSERQCRKDNCVTVPNSGQEDVDQDGIGDACDPDADGDGVLNEKDNCPLVRNPDQRNTDGDKWGDACDNCRSQKNDDQNDTDKDGRGDACDDDIHGDRIRNPVDNCPKVPNSDQKDTDGDGVGDACDNCPQKSNADQRDVDHDFVGDACDSDQDQDGDGHQDSKDNCPTVPNSAQQDSDHDGQGDACDDDDDNDGVPDSRDNCRLVPNPGQEDMDRDGVGDACQGDFDADKVVDKIDVCPENAEVTLTDFRAFQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTATDDDYAGFIFGYQDSSSFYVVMWKQMEQTYWQANPFRAVAEPGIQLKAVKSSTGPGEQLRNALWHTGDTASQVRLLWKDPRNVGWKDKTSYRWFLQHRPQVGYIRVRFYEGPELVADSNVILDTTMRGGRLGVFCFSQENIIWANLRYRCNDTIPEDYEAQRLLQA

Target ORF information:

RefSeq Version	NM_001166517.1
Organism	Bos taurus(cattle)
Definition	Bos taurus cartilage oligomeric matrix protein (COMP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166517.1

ORF Insert Sequence:

ATGGTTCTCG CCGCCGCCCG CGTTCTCTTG CTCACGCTGG CTGCCCTCGG GGCATCAGGC 
CAGGGGCAGA TGCCGCTGGG TGGGGACCTG GGCCCGCAGA TGCTACGCGA ACTCCAGGAG 
ACCAACGCGG CCCTGCAGGA CGTACGGGAC CTACTGCGGC AGCAGGTCAA GGAGATTACG 
TTCCTGAAAA ACACGGTGAT GGAGTGTGAC GCGTGCGGGA TGCAACCCGC GCGAACCCCC 
AAACTGACGG TACGGCCGCT AAGCCAGTGT TCGCCCGGCT TCTGCTTCCC CGGAGTGGCT 
TGTACCGAGA CAGCCAACGG CGCGCGCTGC GGACCCTGCC CCGAAGGTTT CACAGGCAAC 
GGCTCGCACT GCGCCGACGT CAACGAGTGC ACTGCCCATC CTTGCTTCCC TCGCGTTCGC 
TGCATCAATA CCAGTCCGGG CTTCCGCTGC GAGGCTTGCC CACCTGGGTT CAGCGGCCCC 
ACCCATGAGG GCGTGGGGCT GGCCTTCGCC AAGGCCAACA AGCAGGTTTG TACGGACATT 
AACGAGTGTG AGACCGGGCA GCATAACTGC GTCCCCAACT CTGTATGCGT CAATACCGTG 
GGCTCCTTCC AGTGTGGCCC TTGCCAGCCC GGCTTCGTGG GCGACCAGGC ATCAGGCTGC 
CGTCGGCGGC CACAGCGCTT CTGCCCTGAC GGCACGCCCA GCCCGTGCCA CGAGAAGGCC 
GACTGCGTCC TAGAGCGTGA TGGGTCGCGA TCTTGCGTGT GCGCCGTCGG CTGGGCTGGC 
AATGGGCTCA TCTGCGGCCG CGACACAGAC TTAGACGGCT TTCCGGACGA GAAGCTACGC 
TGCTCTGAGC GCCAGTGCAG AAAGGACAAC TGCGTGACGG TGCCCAACTC AGGGCAGGAG 
GATGTGGACC AGGACGGCAT CGGAGACGCC TGCGACCCGG ACGCCGACGG GGACGGCGTC 
CTCAATGAGA AGGACAACTG CCCGCTCGTG CGGAACCCAG ACCAGCGAAA TACGGATGGC 
GACAAGTGGG GCGATGCGTG CGACAACTGT CGGTCCCAGA AGAACGACGA CCAGAATGAC 
ACAGATAAGG ACGGCCGAGG CGACGCCTGC GACGACGACA TACACGGCGA CCGGATCCGC 
AATCCGGTGG ACAACTGCCC CAAGGTGCCC AACTCAGATC AGAAAGACAC TGATGGTGAT 
GGTGTAGGAG ATGCCTGTGA CAACTGTCCT CAGAAGAGCA ACGCAGACCA GAGGGATGTG 
GACCACGACT TCGTGGGAGA TGCTTGTGAC AGCGACCAAG ACCAGGATGG GGATGGGCAC 
CAGGACTCGA AGGACAACTG CCCTACAGTG CCCAACAGTG CCCAGCAGGA CTCAGACCAC 
GATGGCCAGG GTGACGCCTG CGACGACGAT GACGACAATG ATGGGGTCCC CGACAGTAGG 
GACAACTGCC GTCTAGTGCC CAACCCGGGC CAGGAAGACA TGGACCGCGA CGGCGTGGGT 
GACGCGTGCC AGGGCGACTT TGATGCGGAC AAGGTGGTAG ACAAGATCGA TGTGTGTCCG 
GAGAACGCTG AGGTCACACT CACCGACTTC CGGGCCTTCC AGACGGTCGT GCTGGACCCT 
GAGGGCGACG CACAGATAGA CCCTAACTGG GTGGTGCTCA ACCAGGGTAT GGAGATCGTA 
CAGACGATGA ACAGCGACCC AGGCCTGGCT GTGGGTTACA CGGCCTTCAA TGGCGTGGAT 
TTCGAAGGCA CGTTCCACGT GAACACTGCC ACGGATGACG ACTACGCTGG TTTCATCTTT 
GGCTACCAGG ACAGCTCCAG CTTCTATGTG GTCATGTGGA AGCAGATGGA GCAGACGTAC 
TGGCAGGCGA ACCCCTTCCG TGCGGTGGCA GAGCCCGGCA TCCAGCTCAA GGCCGTGAAG 
TCCTCCACAG GCCCTGGGGA GCAGCTTCGG AACGCACTGT GGCACACAGG GGACACAGCG 
TCACAGGTGC GGCTGCTGTG GAAGGATCCC CGGAACGTGG GCTGGAAGGA CAAGACATCC 
TACCGCTGGT TCCTGCAGCA CCGGCCCCAA GTGGGCTATA TTAGAGTGCG ATTCTACGAG 
GGCCCAGAGC TGGTGGCAGA CAGCAACGTG ATCCTGGATA CGACCATGCG GGGCGGTCGT 
CTGGGGGTCT TCTGCTTCTC CCAGGAGAAC ATCATCTGGG CCAACCTGCG CTACCGCTGC 
AACGACACCA TCCCCGAGGA CTACGAGGCC CAGAGGCTGC TGCAGGCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Differential response of cartilage oligomeric matrix protein (COMP) to morphogens of bone morphogenetic protein/transforming growth factor-β family in the surface, middle and deep zones of articular cartilage.
Journal of tissue engineering and regenerative medicine5(6)e87-96(2011 Jun)
Motaung SC,Di Cesare PE,Reddi AH

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Marçais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

COMP acts as a catalyst in collagen fibrillogenesis.
The Journal of biological chemistry282(43)31166-73(2007 Oct)
Halász K,Kassner A,Mörgelin M,Heinegård D

Expression of PSACH-associated mutant COMP in tendon fibroblasts leads to increased apoptotic cell death irrespective of the secretory characteristics of mutant COMP.
Matrix biology : journal of the International Society for Matrix Biology26(4)314-23(2007 May)
Weirich C,Keene DR,Kirsch K,Heil M,Neumann E,Dinser R

Effects of simple and complex motion patterns on gene expression of chondrocytes seeded in 3D scaffolds.
Tissue engineering12(11)3171-9(2006 Nov)
Grad S,Gogolewski S,Alini M,Wimmer MA

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

COMP cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM