ORF » Species Summary » Homo sapiens » Reactome

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Homo sapiens (human)

Browse by Letter Index, Genomic Locus


Collagen biosynthesis and modifying enzymes ECM proteoglycans
Ligand-independent caspase activation via DCC Cytochrome c-mediated apoptotic response
Breakdown of the nuclear lamina Activation of DNA fragmentation factor
Stimulation of the cell death response by PAK-2p34 Regulation of Apoptosis
Sema4D in semaphorin signaling Sema4D mediated inhibition of cell attachment and migration
Sema4D induced cell migration and growth-cone collapse NCAM1 interactions
Netrin mediated repulsion signals NrCAM interactions
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells
Transcriptional regulation of pluripotent stem cells Base-Excision Repair, AP Site Formation
Recognition and association of DNA glycosylase with site containing an affected purine Abasic sugar-phosphate removal via the single-nucleotide replacement pathway
Translesion synthesis by REV1 Translesion Synthesis by POLH
Regulation of Hypoxia-inducible Factor (HIF) by oxygen Regulation of gene expression by Hypoxia-inducible Factor
HSF1-dependent transactivation Attenuation phase
DNA Damage/Telomere Stress Induced Senescence Chromatin modifying enzymes
Metal sequestration by antimicrobial proteins RAS signaling downstream of NF1 loss-of-function variants
Keratinization Gene Expression
Minus-strand DNA synthesis Integration of viral DNA into host genomic DNA
HIV Transcription Elongation Tat-mediated HIV elongation arrest and recovery
Synthesis And Processing Of GAG, GAGPOL Polyproteins Host Interactions of HIV factors
Interactions of Vpr with host cellular proteins Vpr-mediated nuclear import of PICs
Nef and signal transduction Virus Assembly and Release
NS1 Mediated Effects on Host Pathways Toxicity of tetanus toxin (TeNT)
IRAK4 deficiency (TLR2/4) MyD88 deficiency (TLR5)
Class I MHC mediated antigen processing & presentation ER-Phagosome pathway
Toll Like Receptor 5 (TLR5) Cascade Toll Like Receptor TLR1:TLR2 Cascade
Toll Like Receptor TLR6:TLR2 Cascade Metabolism
The citric acid (TCA) cycle and respiratory electron transport Respiratory electron transport
HIV Infection HIV Life Cycle
2-LTR circle formation Autointegration results in viral DNA circles
Late Phase of HIV Life Cycle Rev-mediated nuclear export of HIV RNA
Membrane binding and targetting of GAG proteins Budding and maturation of HIV virion
Interactions of Rev with host cellular proteins APOBEC3G mediated resistance to HIV-1 infection
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters Transport of Ribonucleoproteins into the Host Nucleus
NEP/NS2 Interacts with the Cellular Export Machinery Latent infection of Homo sapiens with Mycobacterium tuberculosis
Toxicity of botulinum toxin type B (BoNT/B) IRAK4 deficiency (TLR5)
Antigen processing-Cross presentation Toll Like Receptor 10 (TLR10) Cascade
Activated TLR4 signalling MyD88:Mal cascade initiated on plasma membrane
Toll Like Receptor 2 (TLR2) Cascade The IPAF inflammasome
Interferon Signaling Cell surface interactions at the vascular wall
InlA-mediated entry of Listeria monocytogenes into host cells C-type lectin receptors (CLRs)
Dectin-2 family Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
Reverse Transcription of HIV RNA Transcription of the HIV genome
Tat-mediated elongation of the HIV-1 transcript Assembly Of The HIV Virion
Interactions of Tat with host cellular proteins Nef mediated downregulation of CD28 cell surface expression
Influenza Infection Viral mRNA Translation
Host Interactions with Influenza Factors Response of Mtb to phagocytosis
MyD88 deficiency (TLR2/4) MyD88 cascade initiated on plasma membrane
Listeria monocytogenes entry into host cells InlB-mediated entry of Listeria monocytogenes into host cell
Toll Like Receptor 4 (TLR4) Cascade Inflammasomes
Defensins Alpha-defensins
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