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Homo sapiens (human)

Browse by Letter Index, Genomic Locus


Retinoid metabolism and transport The canonical retinoid cycle in rods (twilight vision)
RA biosynthesis pathway GLI3 is processed to GLI3R by the proteasome
FasL/ CD95L signaling Nuclear Receptor transcription pathway
RNA Polymerase I Transcription Initiation RNA Polymerase III Chain Elongation
Mitochondrial transcription initiation RNA Polymerase II Promoter Escape
Formation of the Early Elongation Complex mRNA Splicing - Major Pathway
Transport of Mature Transcript to Cytoplasm Transport of the SLBP independent Mature mRNA
Processing of Intronless Pre-mRNAs C6 deamination of adenosine
Deadenylation-dependent mRNA decay mRNA decay by 3' to 5' exoribonuclease
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Transcriptional regulation by small RNAs
PIWI-interacting RNA (piRNA) biogenesis Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
HuR (ELAVL1) binds and stabilizes mRNA Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA
SIRT1 negatively regulates rRNA Expression Autodegradation of the E3 ubiquitin ligase COP1
Transcriptional activation of p53 responsive genes G2/M Checkpoints
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components Synthesis of DNA
Switching of origins to a post-replicative state Mitotic G2-G2/M phases
Recruitment of NuMA to mitotic centrosomes Nuclear Envelope Breakdown
Nuclear Pore Complex (NPC) Disassembly Clearance of Nuclear Envelope Membranes from Chromatin
Mitotic Prometaphase Resolution of Sister Chromatid Cohesion
Mitotic Metaphase/Anaphase Transition Initiation of Nuclear Envelope Reformation
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
Deposition of new CENPA-containing nucleosomes at the centromere Telomere Extension By Telomerase
Polymerase switching on the C-strand of the telomere RORA activates gene expression
Vesicle-mediated transport Gap junction trafficking
Oligomerization of connexins into connexons Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
Scavenging by Class H Receptors ABC transporters in lipid homeostasis
SLC-mediated transmembrane transport Sodium/Proton exchangers
Cation-coupled Chloride cotransporters Amino acid transport across the plasma membrane
Proton-coupled neutral amino acid transporters Hexose transport
Class II GLUTs Inositol transporters
Zinc influx into cells by the SLC39 gene family Ligand-gated ion channel transport
Stimuli-sensing channels Glycogen synthesis
Hyaluronan metabolism Synthesis of IPs in the nucleus
Synthesis of pyrophosphates in the cytosol Digestion of dietary lipid
HDL-mediated lipid transport Mitochondrial Fatty Acid Beta-Oxidation
mitochondrial fatty acid beta-oxidation of saturated fatty acids Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids Cap-dependent Translation Initiation
Eukaryotic Translation Elongation Peptide chain elongation
Chaperonin-mediated protein folding Post-chaperonin tubulin folding pathway
Gamma carboxylation, hypusine formation and arylsulfatase activation Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
Removal of aminoterminal propeptides from gamma-carboxylated proteins Synthesis of substrates in N-glycan biosythesis
Synthesis of GDP-mannose ER Quality Control Compartment (ERQC)
COPII (Coat Protein 2) Mediated Vesicle Transport Reactions specific to the complex N-glycan synthesis pathway
N-Glycan antennae elongation O-linked glycosylation of mucins
SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9)
SUMO E3 ligases SUMOylate target proteins Metabolism of Angiotensinogen to Angiotensins
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
ATF6 (ATF6-alpha) activates chaperones IRE1alpha activates chaperones
Neuronal System Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels
Reuptake of GABA Degradation of GABA
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