ORF » Species Summary » Homo sapiens » Reactome

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Homo sapiens (human)

Browse by Letter Index, Genomic Locus


Enzymatic degradation of dopamine by COMT Acetylcholine Binding And Downstream Events
Activation of Kainate Receptors upon glutamate binding GABA B receptor activation
Activation of GABAB receptors Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)
TWIK related potassium channel (TREK) Cilium Assembly
Signaling by EGFRvIII in Cancer Constitutive Signaling by EGFRvIII
Signaling by activated point mutants of FGFR1 Signaling by FGFR2 amplification mutants
Signaling by activated point mutants of FGFR3 PI3K/AKT Signaling in Cancer
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Signaling by TGF-beta Receptor Complex in Cancer
TGFBR2 Kinase Domain Mutants in Cancer TGFBR1 LBD Mutants in Cancer
AXIN mutants destabilize the destruction complex, activating WNT signaling AXIN missense mutants destabilize the destruction complex
phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex S45 mutants of beta-catenin aren't phosphorylated
T41 mutants of beta-catenin aren't phosphorylated Misspliced GSK3beta mutants stabilize beta-catenin
Misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling Diseases associated with visual transduction
Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate
Defective CHST6 causes MCDC1 Formation of the HIV-1 Early Elongation Complex
Toxicity of botulinum toxin type F (BoNT/F) Toxicity of botulinum toxin type G (BoNT/G)
TICAM1 deficiency - HSE TCR signaling
Phosphorylation of CD3 and TCR zeta chains CD28 dependent Vav1 pathway
MHC class II antigen presentation Activation of the AP-1 family of transcription factors
TRAF6 mediated induction of TAK1 complex Toll Like Receptor 9 (TLR9) Cascade
Activation of C3 and C5 SUMOylation of DNA replication proteins
Protein repair Cardiac conduction
tRNA modification in the mitochondrion HHAT G278V abrogates palmitoylation of Hh-Np
IL-6-type cytokine receptor ligand interactions Cholesterol biosynthesis via desmosterol
Metabolism of vitamin K Metabolism of ingested SeMet, Sec, MeSec into H2Se
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Regulation of cholesterol biosynthesis by SREBP (SREBF) Activation of gene expression by SREBF (SREBP)
Metabolism of steroid hormones Glucocorticoid biosynthesis
Estrogen biosynthesis Vitamin D (calciferol) metabolism
Synthesis of PA Synthesis of PS
Acyl chain remodelling of PS Acyl chain remodelling of PI
Synthesis of PG Synthesis of PIPs at the ER membrane
Synthesis of PIPs at the plasma membrane Synthesis of PIPs at the early endosome membrane
Linoleic acid (LA) metabolism Sphingolipid metabolism
Sphingolipid de novo biosynthesis Integration of energy metabolism
Acetylcholine regulates insulin secretion Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
eNOS activation Pyruvate metabolism and Citric Acid (TCA) cycle
Pyrimidine catabolism Vitamins B6 activation to pyridoxal phosphate
Cobalamin (Cbl, vitamin B12) transport and metabolism Biotin transport and metabolism
Nicotinate metabolism Nicotinamide salvaging
Molybdenum cofactor biosynthesis Metabolism of amino acids and derivatives
Serine biosynthesis Branched-chain amino acid catabolism
Phenylalanine and tyrosine catabolism Metabolism of polyamines
Amine-derived hormones Catecholamine biosynthesis
Thyroxine biosynthesis Serotonin and melatonin biosynthesis
Phase 1 - Functionalization of compounds Formation of the active cofactor, UDP-glucuronate
Conjugation of carboxylic acids Conjugation of phenylacetate with glutamine
Electron transport from NADPH to Ferredoxin Abacavir metabolism
Adherens junctions interactions Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Nephrin interactions Extracellular matrix organization
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