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ampicillin

an antibiotic frequently used in the selection of bacterial transformants containing a cloning vector encoding resistance to this antibiotic, generally because of the presence of an ampicillin resistance gene derived from a transposable element. While this antibiotic is considered bacteriocidal in liquid culture, causing sensitive cells to lyse or rupture, it is bacteriostatic in solid media, allowing sensitive cells to exist as viable sphereoplasts with damaged cell walls until the ampicillin in the media degrades, allowing continued cell growth. This antibiotic is inactivated by the ampicillin resistance gene present in many cloning vectors.

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If you know of any terms that have been omitted from this glossary that you feel would be useful to include, please send detail to the Editorial Office at GenScript: website@genscript.com

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