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List by Alphabet: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

s Related Biological Terms:

S

(see R)

ACS

Anomalously replicating consensus sequence. (see origin recognition complex (ORC))

AP site

A position in a double-stranded DNA sequence that is missing an A or G base (apurinic) or a C or T base (apyrimidinic).

ARMS

amplification of refractory mutation system. (see PCR amplification of specific alleles)

ARS

anomalously replicating sequence. (see origin recognition complex (ORC))

AS-ODN

antisense oligodeoxyribonucleotide. (see antisense)

ASA

allele-specific amplification (see PCR amplification of specific alleles)ANDapolar water-accessible surface area

ASPCR

(= allele-specific PCR (ASPCR))

ATPase

An enzyme that hydrolyses ATP; usually the partial activity of an enzyme, or system of enzymes, that uses the energy made available by the hydrolysis of ATP to drive an energetically unfavourable process, e.g. the Na+/K+-ATPase of cell membranes.

Abu shunt

An alternative pathway in bacteria and higher plants for entry of glutamate into the tricarboxylic acid cycle: glutamate-aminobutyrate (Abu) succinic acid semialdehyde succinate.

Achilles heel cleavage

A method for cleaving of DNA at very specific sequences. The site of cleavage is able to bind a specific protein, e.g. the lac repressor, that already contains a restriction site or is engineered to contain one; the presence of the DNA-binding protein protects the restriction site while the rest of the DNA is enzymically methylated, thus eliminating all unprotected restriction sites. Upon removal of the binding protein, the DNA can be cleaved at the one remaining restriction site. Roberts, L. (1990) Science 249, 127

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