itga5.L cDNA ORF clone, Xenopus laevis(African clawed frog)

Gene
Clones
gRNAs

Summary

Gene Symbol	itga5.L
Entrez Gene ID	394366
Full Name	integrin subunit alpha 5 L homeolog
Synonyms	itga5,itga5-A
General protein information	Preferred Names integrin subunit alpha 5 L homeolog Names integrin alpha-5 VLA-5 fibronectin receptor subunit alpha integrin alpha 5 subunit integrin alpha-F integrin alpha5 subunit integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
Gene Type	protein-coding
Organism	Xenopus laevis(African clawed frog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001087603.1	NP_001081072.1	integrin alpha-5 precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Integrin alpha5beta1 function is regulated by XGIPC/kermit2 mediated endocytosis during Xenopus laevis gastrulation.
Spicer E, Suckert C, Al-Attar H, Marsden M
PloS one5(5)e10665(2010 May)

Integrin alpha5 is required for somite rotation and boundary formation in Xenopus.
Kragtorp KA, Miller JR
Developmental dynamics : an official publication of the American Association of Anatomists236(9)2713-20(2007 Sep)

Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative.
Klein SL, Strausberg RL, Wagner L, Pontius J, Clifton SW, Richardson P
Developmental dynamics : an official publication of the American Association of Anatomists225(4)384-91(2002 Dec)

Integrin alpha 5 during early development of Xenopus laevis.
Joos TO, Whittaker CA, Meng F, DeSimone DW, Gnau V, Hausen P
Mechanisms of development50(2-3)187-99(1995 Apr)

Integrin alpha subunit mRNAs are differentially expressed in early Xenopus embryos.
Whittaker CA, DeSimone DW
Development (Cambridge, England)117(4)1239-49(1993 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following itga5.L gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the itga5.L cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OAf00740	NM_001087603.1 Latest version!	Xenopus laevis integrin subunit alpha 5 L homeolog (itga5.L), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

itga5.L ( NM_001087603.1 ) cDNA ORF clone, Xenopus laevis(African clawed frog) -> NP_001081072.1 Xenopus laevis integrin subunit alpha 5 L homeolog (itga5.L), mRNA.

Price & Availability↑

CloneID	OAf00740
Clone ID Related Accession (Same CDS sequence)	NM_001087603.1
Accession Version	NM_001087603.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3153bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Xenopus laevis(African clawed frog)
Product	integrin alpha-5 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U12683.1. On Jul 25, 2007 this sequence version replaced NM_001087604.1. ##Evidence-Data-START## Transcript exon combination :: U12683.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00012418, SAMD00012419 [ECO:0000348] ##Evidence-Data-END##

ATGCAGCTCC CACGAGGCTC CCGTGTCCCT GGGCTAGTGG CCACGTTCTT GTTCCCTGTG 
CTGTGCGCGC TGCTCACCTT CAGCTCAGTC CGTGGATTTA ACTTGGCAGT GGAGCAGCCG 
GCAGTTTACA CGGGGGCAAG TGGCAGCTTC TTTGGTTTCT CTGTGGACTT CTACCTCCCA 
GACGCGCAGA GCATCAGTAT CCTGGTGGGG GCCCCCAAGG CAAATACCAG CCAGCCCGGA 
GTGTTTGAGG GGGGAGCTGT GTTTTATTGC CCCTGGCAAA GAAATGGCAC CAACTGCACA 
GAAATCAGCT TTGACTCACA TGGTGACCGG CAGCGAGAAC TTTTCGATAC TCCCCAACCC 
AAACACATGG AATCCAAGTC CGAGCAATGG TTTGGTGCTA CTGTCCGGGC ACATGGGAAA 
ACGATACTGG CCTGTGCTCC ACGATACAGC TGGAGAACCG AAAAGGAAGA AAAGCGCAGT 
GACCCTGTGG GTACCTGTTA CTTATCTGTC AACAACTTCA CCACATTTGT AGAGTATTCA 
CCCTGCCGCA CAGATTTCAG TGATGCTGCT GGTCAAGGGT ACTGCCAAGG AGGCTTCAGT 
GCTGAGTTTA CAAAGAGTGG AAGAGTTTTA CTGGGTGGAC CGGGCAGCTA CTTCTGGCAA 
GGTCAGGTGA TCACTGCAAC ACAGGATGAG ATCCAGGAGG CTTATTATCC AGAATATTTT 
GTGCTGGAGT ACAAGAAACA AATGCAGACA CGACAGGCGG CTTCATCATA TGATGACAGT 
TACTTTGGTT ATTCAGTTGC AGTTGGTGAA TTCAGTGAAG ATGCTACTGA AGATTTCGTT 
GTGGGTGTTC CCAAAGGAAA CATAACTTAT GGCTATGTGA CTATACTGAA TGGGACAGAT 
TTGAGATCCT TGTATAACTT TTCAGGTGAA CAGATGGCCT CCTATTTTGG GTATTCTGTG 
TCGGCTACCG ACCTCAATAG TGATGGACTA GATGACCTGT TAATCGGAGC ACCACTCTTT 
ATGGATAGGA CCCATGATGG CAGGGTGCAG GAAGTTGGAC GTGTTTATGT TTACCTGCAG 
GGAGACCATA TGGAAAGCAC ACCCCATCTG ATCCTTACTG GCATGGAAGA ATATGGCCGA 
TTCGGTAGTT CCATTGCATC CCTAGGAGAT TTGGACCAGG ATGGGTTTAA TGATATTGCC 
ATTGGTGCTC CTTTTGGAGG AGAGGCCCAA AGAGGAGCAG TTTTCATTTT TAATGGCCAG 
CCAGGAGGTG TTGATTCCAA GCCATCACAG GTGCTGCAAG GACAGTGGGG CTCCTCTCAA 
CAGCCTTCAT TCTTTGGTTT GTCCACCAGG GGAGGGCACG ATCTTGATGG AAATGGCTAT 
CCAGATCTCA TTGTAGGTGC GTTTGGTGTG GATACGACTT TGGTTTACAG GGGACGTCCC 
ATTATTCATG CTAGTGCCTC CCTCTCCATC TCCCCCAATA TGTTTAACCC AGAGGAGAAG 
ACCTGTACAC TTGAAGGAAA TGCCAGTGCA GTATCCTGCA TAAACCTTAG TTTCTGCTTG 
AATGCTTCAG GAAAGCACGT GCCTAACTCT ATAGGAATTA AAGTCGAGCT ACAGCTGGAC 
CAGACGAAGC AGAAGGGAGC GGTGAAGCGA GCATTGTTCC TGAAAACCCG CCAGCCCCAG 
CTGACCCAGA CTATTCATTT ACTGAATGGA GGCAAAGAGG AATGTCGTGC CATGAAGATC 
TACCTCAGGG AGGAGTCAGA GTTTCGGGAC AAGCTCTCTC CAATTTACGT TGGTCTGAAT 
TTCTCCCTGG ATCCACTGGC ACCAGCCGAT GCCCATGGTC TCATGCCCAT CTTCAATTAC 
AAGACCAAGA ACTATATTGA GCAGAAGGCT CAGATCCAGT TGGACTGTGG GGAAGATAAC 
ATCTGTGTGC CAGATCTGAA GCTCAATGTC TCAGGTGACC GGAAATCTGT ATATCTTGGA 
GACGAGAACT TCTTGACATT GTTCTTCAAT GCTCAGAACC TTGGGGGAGG AGCCTACGAG 
GCGGAACTGT ATGTCACATT GCCCCCAGAG GCAGAGTACA GTGGCATAGT GAGGAACAAT 
GAGCATCTCT TGATTTTACC TTGTGCTTAC GAGATGGAGA ATCAGACCCG ACTGGTCATC 
TGTGACCTAG GAAACCCAAT GAAGGCAGGG GCCAGTCTTG CAGGGGGTCT GAGATTCACG 
GTGCCACATC TACGTGACTC CAGCCATAAA GTTCAGTTTG ACTTCCAGAT CCGCAGCAAA 
AATCAAAATA ACTCCCAAAG TGAGACGGTG CACTTGGCGT TGAATGTTGA AGCCCACAGT 
ACAGTGTCAT TTTTCGGTGC CTCAAAGCCA GATAGTGTTA TCTTCCCTGT TGCAAACTGG 
AAACCTGGCA GGAATCCCGT GACCGGACAA GAGGCAGGTC CAGAGGTCAA ACATGTGTAT 
GAGCTGGTCA ACTTTGGGCC AAGTTCCATC AGTCAAGGAA TCCTGGAACT GAGATGTCCA 
ATGAGAGTCA ACAAGGAATA TGCTATGTAT GTGATGTCTT ATGCTGTGCA AGGATTGACT 
AACTGCACCT CCAATCACCC AGCTAATGCC CTACATTTAC AGCATTCACC CACAGACCAC 
CCACCAACGC TGAATCCCAA AACTGTCCAC CACGTGGAAA GGCGAGATAC TGCCCGACTC 
ATCTCAGGAT CTTCTAATGT TTTGAAATGC AACGAACCCC ATGTGGACTG CTTCCATCTA 
CACTGTGATG TTGGGCCGCT AGAGAAACAA AAGCGAGCCA TCCTAAGGGT GAATTTCCTC 
GTATGGGCCA ACACCTTCAT GCAGAAGGAA AACCAGGGAT TCACTCTTCA GTGTGACGCA 
CTCTATCATA TACAGAAGCT GCCGTACAAA ATTCTCCCCC ACGTGTATCC TAAAGGGACA 
CATCAGGTGG ACACTGCAAT TCACTGGGCC AAACCTGAAA GTAGCTATGG AGTCCCACTA 
TGGATCATTA TATTGGCTAT TCTAATTGGA CTTCTCCTGC TTGCATTGCT TATATATGTC 
CTGTATAAGC TCGGCTTCTT TAAACGCTCT TACCAATATG GGACTGCCAT GGAAAAAGCT 
GAGCTCAAGC CCCAGGCTGC ATCAGAGGCT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001081072.1
CDS	49..3201
Translation	MQLPRGSRVPGLVATFLFPVLCALLTFSSVRGFNLAVEQPAVYTGASGSFFGFSVDFYLPDAQSISILVGAPKANTSQPGVFEGGAVFYCPWQRNGTNCTEISFDSHGDRQRELFDTPQPKHMESKSEQWFGATVRAHGKTILACAPRYSWRTEKEEKRSDPVGTCYLSVNNFTTFVEYSPCRTDFSDAAGQGYCQGGFSAEFTKSGRVLLGGPGSYFWQGQVITATQDEIQEAYYPEYFVLEYKKQMQTRQAASSYDDSYFGYSVAVGEFSEDATEDFVVGVPKGNITYGYVTILNGTDLRSLYNFSGEQMASYFGYSVSATDLNSDGLDDLLIGAPLFMDRTHDGRVQEVGRVYVYLQGDHMESTPHLILTGMEEYGRFGSSIASLGDLDQDGFNDIAIGAPFGGEAQRGAVFIFNGQPGGVDSKPSQVLQGQWGSSQQPSFFGLSTRGGHDLDGNGYPDLIVGAFGVDTTLVYRGRPIIHASASLSISPNMFNPEEKTCTLEGNASAVSCINLSFCLNASGKHVPNSIGIKVELQLDQTKQKGAVKRALFLKTRQPQLTQTIHLLNGGKEECRAMKIYLREESEFRDKLSPIYVGLNFSLDPLAPADAHGLMPIFNYKTKNYIEQKAQIQLDCGEDNICVPDLKLNVSGDRKSVYLGDENFLTLFFNAQNLGGGAYEAELYVTLPPEAEYSGIVRNNEHLLILPCAYEMENQTRLVICDLGNPMKAGASLAGGLRFTVPHLRDSSHKVQFDFQIRSKNQNNSQSETVHLALNVEAHSTVSFFGASKPDSVIFPVANWKPGRNPVTGQEAGPEVKHVYELVNFGPSSISQGILELRCPMRVNKEYAMYVMSYAVQGLTNCTSNHPANALHLQHSPTDHPPTLNPKTVHHVERRDTARLISGSSNVLKCNEPHVDCFHLHCDVGPLEKQKRAILRVNFLVWANTFMQKENQGFTLQCDALYHIQKLPYKILPHVYPKGTHQVDTAIHWAKPESSYGVPLWIIILAILIGLLLLALLIYVLYKLGFFKRSYQYGTAMEKAELKPQAASEA

Target ORF information:

RefSeq Version	NM_001087603.1
Organism	Xenopus laevis(African clawed frog)
Definition	Xenopus laevis integrin subunit alpha 5 L homeolog (itga5.L), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001087603.1

ORF Insert Sequence:

ATGCAGCTCC CACGAGGCTC CCGTGTCCCT GGGCTAGTGG CCACGTTCTT GTTCCCTGTG 
CTGTGCGCGC TGCTCACCTT CAGCTCAGTC CGTGGATTTA ACTTGGCAGT GGAGCAGCCG 
GCAGTTTACA CGGGGGCAAG TGGCAGCTTC TTTGGTTTCT CTGTGGACTT CTACCTCCCA 
GACGCGCAGA GCATCAGTAT CCTGGTGGGG GCCCCCAAGG CAAATACCAG CCAGCCCGGA 
GTGTTTGAGG GGGGAGCTGT GTTTTATTGC CCCTGGCAAA GAAATGGCAC CAACTGCACA 
GAAATCAGCT TTGACTCACA TGGTGACCGG CAGCGAGAAC TTTTCGATAC TCCCCAACCC 
AAACACATGG AATCCAAGTC CGAGCAATGG TTTGGTGCTA CTGTCCGGGC ACATGGGAAA 
ACGATACTGG CCTGTGCTCC ACGATACAGC TGGAGAACCG AAAAGGAAGA AAAGCGCAGT 
GACCCTGTGG GTACCTGTTA CTTATCTGTC AACAACTTCA CCACATTTGT AGAGTATTCA 
CCCTGCCGCA CAGATTTCAG TGATGCTGCT GGTCAAGGGT ACTGCCAAGG AGGCTTCAGT 
GCTGAGTTTA CAAAGAGTGG AAGAGTTTTA CTGGGTGGAC CGGGCAGCTA CTTCTGGCAA 
GGTCAGGTGA TCACTGCAAC ACAGGATGAG ATCCAGGAGG CTTATTATCC AGAATATTTT 
GTGCTGGAGT ACAAGAAACA AATGCAGACA CGACAGGCGG CTTCATCATA TGATGACAGT 
TACTTTGGTT ATTCAGTTGC AGTTGGTGAA TTCAGTGAAG ATGCTACTGA AGATTTCGTT 
GTGGGTGTTC CCAAAGGAAA CATAACTTAT GGCTATGTGA CTATACTGAA TGGGACAGAT 
TTGAGATCCT TGTATAACTT TTCAGGTGAA CAGATGGCCT CCTATTTTGG GTATTCTGTG 
TCGGCTACCG ACCTCAATAG TGATGGACTA GATGACCTGT TAATCGGAGC ACCACTCTTT 
ATGGATAGGA CCCATGATGG CAGGGTGCAG GAAGTTGGAC GTGTTTATGT TTACCTGCAG 
GGAGACCATA TGGAAAGCAC ACCCCATCTG ATCCTTACTG GCATGGAAGA ATATGGCCGA 
TTCGGTAGTT CCATTGCATC CCTAGGAGAT TTGGACCAGG ATGGGTTTAA TGATATTGCC 
ATTGGTGCTC CTTTTGGAGG AGAGGCCCAA AGAGGAGCAG TTTTCATTTT TAATGGCCAG 
CCAGGAGGTG TTGATTCCAA GCCATCACAG GTGCTGCAAG GACAGTGGGG CTCCTCTCAA 
CAGCCTTCAT TCTTTGGTTT GTCCACCAGG GGAGGGCACG ATCTTGATGG AAATGGCTAT 
CCAGATCTCA TTGTAGGTGC GTTTGGTGTG GATACGACTT TGGTTTACAG GGGACGTCCC 
ATTATTCATG CTAGTGCCTC CCTCTCCATC TCCCCCAATA TGTTTAACCC AGAGGAGAAG 
ACCTGTACAC TTGAAGGAAA TGCCAGTGCA GTATCCTGCA TAAACCTTAG TTTCTGCTTG 
AATGCTTCAG GAAAGCACGT GCCTAACTCT ATAGGAATTA AAGTCGAGCT ACAGCTGGAC 
CAGACGAAGC AGAAGGGAGC GGTGAAGCGA GCATTGTTCC TGAAAACCCG CCAGCCCCAG 
CTGACCCAGA CTATTCATTT ACTGAATGGA GGCAAAGAGG AATGTCGTGC CATGAAGATC 
TACCTCAGGG AGGAGTCAGA GTTTCGGGAC AAGCTCTCTC CAATTTACGT TGGTCTGAAT 
TTCTCCCTGG ATCCACTGGC ACCAGCCGAT GCCCATGGTC TCATGCCCAT CTTCAATTAC 
AAGACCAAGA ACTATATTGA GCAGAAGGCT CAGATCCAGT TGGACTGTGG GGAAGATAAC 
ATCTGTGTGC CAGATCTGAA GCTCAATGTC TCAGGTGACC GGAAATCTGT ATATCTTGGA 
GACGAGAACT TCTTGACATT GTTCTTCAAT GCTCAGAACC TTGGGGGAGG AGCCTACGAG 
GCGGAACTGT ATGTCACATT GCCCCCAGAG GCAGAGTACA GTGGCATAGT GAGGAACAAT 
GAGCATCTCT TGATTTTACC TTGTGCTTAC GAGATGGAGA ATCAGACCCG ACTGGTCATC 
TGTGACCTAG GAAACCCAAT GAAGGCAGGG GCCAGTCTTG CAGGGGGTCT GAGATTCACG 
GTGCCACATC TACGTGACTC CAGCCATAAA GTTCAGTTTG ACTTCCAGAT CCGCAGCAAA 
AATCAAAATA ACTCCCAAAG TGAGACGGTG CACTTGGCGT TGAATGTTGA AGCCCACAGT 
ACAGTGTCAT TTTTCGGTGC CTCAAAGCCA GATAGTGTTA TCTTCCCTGT TGCAAACTGG 
AAACCTGGCA GGAATCCCGT GACCGGACAA GAGGCAGGTC CAGAGGTCAA ACATGTGTAT 
GAGCTGGTCA ACTTTGGGCC AAGTTCCATC AGTCAAGGAA TCCTGGAACT GAGATGTCCA 
ATGAGAGTCA ACAAGGAATA TGCTATGTAT GTGATGTCTT ATGCTGTGCA AGGATTGACT 
AACTGCACCT CCAATCACCC AGCTAATGCC CTACATTTAC AGCATTCACC CACAGACCAC 
CCACCAACGC TGAATCCCAA AACTGTCCAC CACGTGGAAA GGCGAGATAC TGCCCGACTC 
ATCTCAGGAT CTTCTAATGT TTTGAAATGC AACGAACCCC ATGTGGACTG CTTCCATCTA 
CACTGTGATG TTGGGCCGCT AGAGAAACAA AAGCGAGCCA TCCTAAGGGT GAATTTCCTC 
GTATGGGCCA ACACCTTCAT GCAGAAGGAA AACCAGGGAT TCACTCTTCA GTGTGACGCA 
CTCTATCATA TACAGAAGCT GCCGTACAAA ATTCTCCCCC ACGTGTATCC TAAAGGGACA 
CATCAGGTGG ACACTGCAAT TCACTGGGCC AAACCTGAAA GTAGCTATGG AGTCCCACTA 
TGGATCATTA TATTGGCTAT TCTAATTGGA CTTCTCCTGC TTGCATTGCT TATATATGTC 
CTGTATAAGC TCGGCTTCTT TAAACGCTCT TACCAATATG GGACTGCCAT GGAAAAAGCT 
GAGCTCAAGC CCCAGGCTGC ATCAGAGGCT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Integrin alpha5beta1 function is regulated by XGIPC/kermit2 mediated endocytosis during Xenopus laevis gastrulation.
PloS one5(5)e10665(2010 May)
Spicer E,Suckert C,Al-Attar H,Marsden M

Integrin alpha5 is required for somite rotation and boundary formation in Xenopus.
Developmental dynamics : an official publication of the American Association of Anatomists236(9)2713-20(2007 Sep)
Kragtorp KA,Miller JR

Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative.
Developmental dynamics : an official publication of the American Association of Anatomists225(4)384-91(2002 Dec)
Klein SL,Strausberg RL,Wagner L,Pontius J,Clifton SW,Richardson P

Integrin alpha 5 during early development of Xenopus laevis.
Mechanisms of development50(2-3)187-99(1995 Apr)
Joos TO,Whittaker CA,Meng F,DeSimone DW,Gnau V,Hausen P

Integrin alpha subunit mRNAs are differentially expressed in early Xenopus embryos.
Development (Cambridge, England)117(4)1239-49(1993 Apr)
Whittaker CA,DeSimone DW

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itga5.L cDNA ORF clone, Xenopus laevis(African clawed frog)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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