| Gene Symbol | IL4 |
| Entrez Gene ID | 397225 |
| Full Name | interleukin 4 |
| Gene Type | protein-coding |
| Organism | Sus scrofa(pig) |
| Genome |
IVD Raw Materials
ORF » Species Summary » Sus scrofa » IL4 cDNA ORF clone
| Gene Symbol | IL4 |
| Entrez Gene ID | 397225 |
| Full Name | interleukin 4 |
| Gene Type | protein-coding |
| Organism | Sus scrofa(pig) |
| Genome |
| mRNA | Protein | Name |
|---|---|---|
| NM_214123.1 | NP_999288.1 | interleukin-4 precursor |
Interleukin-4 induces up-regulation of endothelial cell claudin-5 through activation of FoxO1: role in protection from complement-mediated injury.
Dalmasso AP, Goldish D, Benson BA, Tsai AK, Wasiluk KR, Vercellotti GM
The Journal of biological chemistry289(2)838-47(2014 Jan)
Invariant NKT cells producing IL-4 or IL-10, but not IFN-gamma, inhibit the Th1 response in experimental autoimmune encephalomyelitis, whereas none of these cells inhibits the Th17 response.
Oh SJ, Chung DH
Journal of immunology (Baltimore, Md. : 1950)186(12)6815-21(2011 Jun)
IL-4 induces protection of vascular endothelial cells against killing by complement and melittin through lipid biosynthesis.
Black SM, Schott ME, Batdorf BH, Benson BA, Rutherford MS, Levay-Young BK, Dalmasso AP
European journal of immunology40(3)803-12(2010 Mar)
Effect of cryopreservation on IL-4, IFNgamma and IL-6 production of porcine peripheral blood lymphocytes.
Li X, Zhong Z, Liang S, Wang X, Zhong F
Cryobiology59(3)322-6(2009 Dec)
Species specialization in cytokine biology: is interleukin-4 central to the T(H)1-T(H)2 paradigm in swine?
Murtaugh MP, Johnson CR, Xiao Z, Scamurra RW, Zhou Y
Developmental and comparative immunology33(3)344-52(2009 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following IL4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OSe00259 | |
| Clone ID Related Accession (Same CDS sequence) | NM_214123.1 | |
| Accession Version | NM_214123.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 402bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 1577116800000 | |
| Organism | Sus scrofa(pig) | |
| Product | interleukin-4 precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X68330.1. ##Evidence-Data-START## Transcript exon combination :: X68330.1, L12991.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN01048372, SAMN01048376 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGGGTCTCA CCTCCCAACT GATCCCAACC CTGGTCTGCT TACTGGCATG TACCAGCAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_999288.1 |
| CDS | 24..425 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_214123.1 |
1 | ATGGGTCTCA CCTCCCAACT GATCCCAACC CTGGTCTGCT TACTGGCATG TACCAGCAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Interleukin-4 induces up-regulation of endothelial cell claudin-5 through activation of FoxO1: role in protection from complement-mediated injury. |
Invariant NKT cells producing IL-4 or IL-10, but not IFN-gamma, inhibit the Th1 response in experimental autoimmune encephalomyelitis, whereas none of these cells inhibits the Th17 response. |
IL-4 induces protection of vascular endothelial cells against killing by complement and melittin through lipid biosynthesis. |
Effect of cryopreservation on IL-4, IFNgamma and IL-6 production of porcine peripheral blood lymphocytes. |
Species specialization in cytokine biology: is interleukin-4 central to the T(H)1-T(H)2 paradigm in swine? |