| Gene Symbol | F2R |
| Entrez Gene ID | 100521609 |
| Full Name | coagulation factor II thrombin receptor |
| Synonyms | Par-1 |
| Gene Type | protein-coding |
| Organism | Sus scrofa(pig) |
IVD Raw Materials
ORF » Species Summary » Sus scrofa » F2R cDNA ORF clone
| Gene Symbol | F2R |
| Entrez Gene ID | 100521609 |
| Full Name | coagulation factor II thrombin receptor |
| Synonyms | Par-1 |
| Gene Type | protein-coding |
| Organism | Sus scrofa(pig) |
| mRNA | Protein | Name |
|---|---|---|
| NM_001244372.1 | NP_001231301.1 | proteinase-activated receptor 1 precursor |
| NM_001244372.2 | NP_001231301.2 | proteinase-activated receptor 1 precursor |
Thrombin activation of proteinase-activated receptor 1 potentiates the myofilament Ca2+ sensitivity and induces vasoconstriction in porcine pulmonary arteries.
Maki J, Hirano M, Hoka S, Kanaide H, Hirano K
British journal of pharmacology159(4)919-27(2010 Feb)
Thrombin stimulates smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1, RhoA, and myocardin.
Martin K, Weiss S, Metharom P, Schmeckpeper J, Hynes B, O'Sullivan J, Caplice N
Circulation research105(3)214-8(2009 Jul)
Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags.
Gorodkin J, Cirera S, Hedegaard J, Gilchrist MJ, Panitz F, Jørgensen C, Scheibye-Knudsen K, Arvin T, Lumholdt S, Sawera M, Green T, Nielsen BJ, Havgaard JH, Rosenkilde C, Wang J, Li H, Li R, Liu B, Hu S, Dong W, Li W, Yu J, Wang J, Staefeldt HH, Wernersson R, Madsen LB, Thomsen B, Hornshøj H, Bujie Z, Wang X, Wang X, Bolund L, Brunak S, Yang H, Bendixen C, Fredholm M
Genome biology8(4)R45(2007)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following F2R gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the F2R cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OSe251965 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001244372.2 | |
| Accession Version | NM_001244372.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1290bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 1555862400000 | |
| Organism | Sus scrofa(pig) | |
| Product | proteinase-activated receptor 1 precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from LUXT01000958.1. On Apr 23, 2019 this sequence version replaced NM_001244372.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR5275382.218615.1, SRR5250921.511903.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103886111, SAMEA103886114 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGGGCCGC GGTGGCTGCT GCTCGTCGCC GCGGGGCTCA GTCTGTGCGG CCCCCTGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001231301.2 |
| CDS | 19..1308 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001244372.2 |
1 | ATGGGGCCGC GGTGGCTGCT GCTCGTCGCC GCGGGGCTCA GTCTGTGCGG CCCCCTGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OSe29763 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001244372.1 | |
| Accession Version | NM_001244372.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1290bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 1469635200000 | |
| Organism | Sus scrofa(pig) | |
| Product | proteinase-activated receptor 1 precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from EW053418.2, CU856323.2, EU056576.1 and CV874145.1. On Sep 17, 2011 this sequence version replaced XM_003123723.1. ##Evidence-Data-START## Transcript exon combination :: EW053418.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02584787 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGGGCCGC GGTGGCTGCT GCTCGTCGCC GCGGGGCTCA GTCTGTGCGG CCCCCTGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001231301.1 |
| CDS | 19..1308 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001244372.1 |
1 | ATGGGGCCGC GGTGGCTGCT GCTCGTCGCC GCGGGGCTCA GTCTGTGCGG CCCCCTGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Thrombin activation of proteinase-activated receptor 1 potentiates the myofilament Ca2+ sensitivity and induces vasoconstriction in porcine pulmonary arteries. |
Thrombin stimulates smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1, RhoA, and myocardin. |
Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags. |