Polg cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Polg
Entrez Gene ID	85472
Full Name	DNA polymerase gamma, catalytic subunit
General protein information	Preferred Names DNA polymerase gamma, catalytic subunit Names DNA polymerase subunit gamma-1 DNA-directed DNA polymerase gamma mitochondrial DNA polymerase catalytic subunit polG-alpha polymerase (DNA directed), gamma polymerase (DNA) gamma, catalytic subunit
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q31
Summary	exhibits DNA polymerase activity; may mediate the final step of mitochondrial DNA repair [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006229410.3	XP_006229472.1	DNA polymerase subunit gamma-1 isoform X2
XM_008759561.2	XP_008757783.1	DNA polymerase subunit gamma-1 isoform X1
NM_053528.1	NP_445980.1	DNA polymerase subunit gamma-1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	POLG	XP_523149.2
Bos taurus (cattle)	POLG	XP_002696610.2
Schizosaccharomyces pombe (fission yeast)	pog1	NP_588025.2
Mus musculus (house mouse)	Polg	NP_059490.2
Gallus gallus (chicken)	POLG	XP_425079.4
Saccharomyces cerevisiae (baker's yeast)	MIP1	NP_014975.2
Canis lupus familiaris (dog)	POLG	XP_005618410.1
Macaca mulatta (Rhesus monkey)	POLG	XP_001092360.1
Neurospora crassa	NCU00276	XP_957747.2
Drosophila melanogaster (fruit fly)	tam	NP_476821.1
Rattus norvegicus (Norway rat)	Polg	NP_445980.1
Eremothecium gossypii	AGOS_ADR357C	NP_984453.1
Xenopus tropicalis (tropical clawed frog)	LOC100488393	XP_002932281.2
Magnaporthe oryzae (rice blast fungus)	MGG_08913	XP_003713942.1
Homo sapiens (human)	POLG	NP_001119603.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000139	XP_311006.5
Danio rerio (zebrafish)	polg	XP_001921130.3

Gene Ontology
Bibliography

Related articles in PubMed

Variants p.Q1236H and p.E1143G in mitochondrial DNA polymerase gamma POLG1 are not associated with increased risk for valproate-induced hepatotoxicity or pancreatic toxicity: A retrospective cohort study of patients with epilepsy.
Hynynen J, Pokka T, Komulainen-Ebrahim J, Myllynen P, Kärppä M, Pylvänen L, Kälviäinen R, Sokka A, Jyrkilä A, Lähdetie J, Haataja L, Mäkitalo A, Ylikotila P, Eriksson K, Haapala P, Ansakorpi H, Hinttala R, Vieira P, Majamaa K, Rantala H, Uusimaa J
Epilepsia59(11)2125-2136(2018 11)

Polymorphisms in POLG were associated with the prognosis and mtDNA content in hepatocellular carcinoma patients.
Long X, Wang X, Chen Y, Guo X, Zhou F, Fan Y, Ge N, Guo M, Zhang Z, Dong G
Bulletin du cancer104(6)500-507(2017 Jun)

Mitochondrial Single-stranded DNA-binding Proteins Stimulate the Activity of DNA Polymerase γ by Organization of the Template DNA.
Ciesielski GL, Bermek O, Rosado-Ruiz FA, Hovde SL, Neitzke OJ, Griffith JD, Kaguni LS
The Journal of biological chemistry290(48)28697-707(2015 Nov)

Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function.
Szczesny B, Brunyanszki A, Olah G, Mitra S, Szabo C
Nucleic acids research42(21)13161-73(2014 Dec)

Acute liver failure after valproate exposure in patients with POLG1 mutations and the prognosis after liver transplantation.
Hynynen J, Komulainen T, Tukiainen E, Nordin A, Arola J, Kälviäinen R, Jutila L, Röyttä M, Hinttala R, Majamaa K, Mäkisalo H, Uusimaa J
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society20(11)1402-12(2014 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Polg gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Polg cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa09810	NM_053528.1 Latest version!	Rattus norvegicus DNA polymerase gamma, catalytic subunit (Polg), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00
ORa22925	XM_006229410.3 Latest version!	Rattus norvegicus polymerase (DNA) gamma, catalytic subunit (Polg), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00
ORa43879	XM_008759561.2 Latest version!	Rattus norvegicus polymerase (DNA) gamma, catalytic subunit (Polg), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Polg ( NM_053528.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_445980.1 Rattus norvegicus DNA polymerase gamma, catalytic subunit (Polg), mRNA.

Price & Availability↑

CloneID	ORa09810
Clone ID Related Accession (Same CDS sequence)	NM_053528.1
Accession Version	NM_053528.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3651bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1575820800000
Organism	Rattus norvegicus(Norway rat)
Product	DNA polymerase subunit gamma-1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ245647.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ245646.1, AJ245647.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGAGCCGCC TGCTCTGGAA GAAGGTGGCC GGCGCCAAAG TCGCCTCAGG GCCAGTACCA 
GCAACAGGAC GCTGGGTCTC CAGCTCCGTC CTCGACCCCG TCCCCAGCGA CGGGCAGCCG 
CAGTCGCAAA TGCCCTCCTC AGAGAATGGG CAGCTGCGGC TCAACCCTCT GCACATCCAG 
ATGCTGTCGA GAGGCCTGCA CGAGCAAATC TTCGGGTGCG GAGGGGACGT GCCCGACGAG 
GCCGCGGTGC AGCGCAGCAT CGAGCACCTA CGGAAGCACG GGCTCTGGGG GCAGCCGACC 
ACGCCCTTGC CAGACGTGCA GCTGCGCCTG CCCCGGCTCT TCGGGGGCAA CCTGGACCAG 
CACTTCCGCC TCCTGGCCCA GAAGCAGAGC CTCCCGTACT TGGAGGCGGC CGCCTCGTTA 
TCGGAGGCCC AATTGCCCCC CCAGCCCAGG AAGTGGGTCT GGGCGGAGGG CTGGACCCGG 
TACGGCCCCG AGGGGGAGGC CGAACCCGTG GCCATCCCCG AGGAGCGGGC CCTGGTGTTC 
GACGTGGAGG TCTGCTTGGC AGAGGGAACC TGCCCCACTT TGGCGGTGGC CATATCCCCC 
TCGGCCTGGT ATTCCTGGTG CAGCCGGCGG CTGGTGGAAG AGCGTTACTC TTGGACCAGC 
CAGCTGTCGC CGGCTGACCT AATCCCTTTG GGGGTCTCTG CTAGTGCCAG CAGCTCCACC 
CAGCAGGATT GGCAGGAACA GTTAGTGGTG GGGCACAATG TTTCCTTTGA CCGAGCCCAT 
ATCAGGGAGC AGTATCTGAT TCAGGGCTCA CGCATGCACT TTCTGGACAC TATGAGCATG 
CACATGGCTA TCTCAGGGCT GAGCAGCTTC CAGCGCAGTC TGTGGATGGG AGCCAAGCAG 
GGCAAGCACA AGACCCAGCA TCCTACAAAG CGAGGTCAGA AGTCCCAGAA GAATGCGAAT 
GGTCCAGCGA TTTCATCTTG GGACTGGATG GACATCAGCA GTGCTAATAA TCTTGCAGAC 
GTGCACAACC TTTATGTGGG GGGACCTCGC TTAGCGAAGG AGCCTCGGGA ACTGTTCGTC 
AAAGGCAGCA TGAGGGATAT CAGGGAGAAC TTCCAGGATC TGATGGAGTA CTGTGCTCGT 
GATGTGTGGG CCACCTTTGA GGTTTTCCAG CAGCAGCTGC CGCTCTTCTT GGAGAGGTGT 
CCCCACCCAG TGACTCTGGC TGGCATGCTG GAGATGGGTG TCTCCTACCT GCCTGTCAAC 
CAGAACTGGG AGCGGTACCT GACAGAGGCA CAGAGCACAT ATGAGGAACT CCAGCGGGAG 
ATGAAGAAGT CGCTGATGGA GCTGGCTAAT GATGCCTGCC AGTTGCTCTC AGGAGAGAGG 
TACAAAGAAG ACCCTTGGCT CTGGGACCTA GAATGGGACT TGCAGGAATT TAAGCAGAAA 
AAGGCAAAGA AGGTGAAGAA GACAGCCTCA GCCAGCAAGT TGCCCATCGA GGGAGCTGGG 
CCCTTTGGGG ATCCCATGGA TCAGGAAGAT CCTGGACCAC CCAGTGAGGA GGAGGAGCTT 
CAGCAAAATA TAATGGCCCA CACCCGTTTA CAGCAGCTGA AGAGCACCAC AGACCTCCTG 
CCTAAGCGAC CCCAACACCT TCCTGGACAC CCTGGGTGGT ACCGGAAACT CTGCCCTCGG 
CTAGATGACC CTGCATGGAC TCCGGGCCCC AGCCTCCTCA GCCTGCAAAT GCGGGTCACT 
CCTAAGCTCA TGGCACTGAC CTGGGATGGT TTTCCTCTAC ACTACTCAGA CTCTCATGGT 
TGGGGCTACC TGGTGCCTGG GCGGCGGGAT AATCTGACTG AGCTGCCAGT GAGCCCCACT 
GAGGAGTCAG CTGCGGTGAC CTGCCCCTAC AGAGCCATCG AGTCCTTGTA CAGGAGGCAC 
TGTCTTGACC AGGGCAAGCA GCAGCTGGAG ACCCAGGAGA CAGACCTGGC TGAGGAGTTC 
TTGCTCACGG ACAGTGCCAT GTGGCAGACG GTAGAAGAAC TGGGCTGCTT AGATGTGGAG 
GCTGAGGCCA CAGTGGAGAG TTCAGGGCTG AGTCAGCCCC TAGTTCCGCC TACTGCTTGT 
GCCCCCAAAA CCAGCCAGCC CACTTATCAC CATGGCAACG GACCTTATAA TGATGTGGAT 
ATCCCCGGTT GCTGGTTTTT CAAGCTGCCT CACAAGGATG GTAACAACTA CAATGTGGGT 
AGTCCCTTTG CCAAAGATTT CCTGCCCAAG ATGGAAGACG GCACTCTGCA GGCTGGCCCA 
GGGGGTGCCA GGGGACCTCG TGCCCTGGAA ATAAATAAAA TGATTTCTTT TTGGAGGAAT 
GCTCATAAAC GCATCAGCTC CCAGATGGTG GTATGGCTCC CCAGGTCAGC TCTGCCCCGG 
GCTGTGACCA GGCACCCCAG CTTTGATGAG GAAAGCCACT ATGGGGCCAT CCTGCCCCAG 
GTGGTGACTG CTGGCACCAT CACCCGTCGC GCTGTGGAGC CCACGTGGCT CACTGCCAGC 
AATGCTCGGC CTGACCGGGT AGGCAGTGAG TTGAAAGCCA TGGTGCAGGC TCCACCTGGC 
TATGTCCTTG TGGGTGCTGA TGTGGACTCA CAGGAACTGT GGATCGCAGC CGTTCTTGGA 
GATGCTCACT TTGCTGGGAT GCATGGCTGC ACGGCCTTTG GCTGGATGAC TCTTCAGGGC 
AGGAAGAGCA GAGGCACTGA TCTGCACAGT AAGACAGCCG CCACTGTGGG CATCAGTCGT 
GAGCACGCCA AAGTCTTCAA CTACGGCCGC ATCTACGGGG CTGGGCAGTC CTTTGCCGAG 
CGCCTGCTGA TGCAGTTCAA CCACAGGCTC TCAAGGCAGG AGGCAGCTGA CAAGGCCCAG 
CAGATGTACG CTGTCACGAA AGGCCTGCGC CGATACCGGC TCTCAGATGA TGGTGAATGG 
CTGGTGAAAC AGTTAAATGT TCCTGTGGAC AGGACAGAAG ACGGCTGGGT TTCCCTACAA 
GATCTTCGAA AGATCCGAAG AGAAGCTTCA AGGAAGTCTC GATGGAAGAA GTGGGAGGTA 
GTCACTGAAC GAGCATGGAC AGGGGGTACG GAGTCAGAAA TGTTTAATAA GCTGGAGAGC 
ATTGCCATGT CTGACACACC ACGCACCCCA GTGCTGGGCT GCTGCATCAG CAGAGCCTTG 
GAGCCCTCGG TTGTCCAGGG AGAGTTTATG ACCAGTCGTG TGAATTGGGT GGTACAGAGC 
TCTGCTGTGG ACTACTTACA CCTCATGCTT GTGGCCATGA AGTGGCTGTT TGAGGAATTT 
GCCATTGATG GGCGCTTCTG CATCAGCATC CATGATGAGG TGCGCTACCT GGTACGTGAG 
GAGGACCGCT ACCGTGCTGC CCTGGCACTG CAGATCACCA ATCTCCTGAC CAGGTGCATG 
TTTGCCTACA AGCTGGGTCT GAATGACCTG CCCCAGTCAG TTGCCTTTTT CAGTGCAGTA 
GACATTGACC AGTGCCTCAG GAAGGAAGTG ACCATGGACT GTAAAACTCC TTCTAACCCA 
ACTGGGATGG AAAGGAAATA CGGGATTCCC CAGGGTGAAG CACTGGATAT TTACCAGATA 
ATTGAACTCA CCAAAGGCTC CTTGGAAAAA CGAAGCCAGC CTGGACCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_445980.1
CDS	1..3651
Translation	MSRLLWKKVAGAKVASGPVPATGRWVSSSVLDPVPSDGQPQSQMPSSENGQLRLNPLHIQMLSRGLHEQIFGCGGDVPDEAAVQRSIEHLRKHGLWGQPTTPLPDVQLRLPRLFGGNLDQHFRLLAQKQSLPYLEAAASLSEAQLPPQPRKWVWAEGWTRYGPEGEAEPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSRRLVEERYSWTSQLSPADLIPLGVSASASSSTQQDWQEQLVVGHNVSFDRAHIREQYLIQGSRMHFLDTMSMHMAISGLSSFQRSLWMGAKQGKHKTQHPTKRGQKSQKNANGPAISSWDWMDISSANNLADVHNLYVGGPRLAKEPRELFVKGSMRDIRENFQDLMEYCARDVWATFEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLTEAQSTYEELQREMKKSLMELANDACQLLSGERYKEDPWLWDLEWDLQEFKQKKAKKVKKTASASKLPIEGAGPFGDPMDQEDPGPPSEEEELQQNIMAHTRLQQLKSTTDLLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSDSHGWGYLVPGRRDNLTELPVSPTEESAAVTCPYRAIESLYRRHCLDQGKQQLETQETDLAEEFLLTDSAMWQTVEELGCLDVEAEATVESSGLSQPLVPPTACAPKTSQPTYHHGNGPYNDVDIPGCWFFKLPHKDGNNYNVGSPFAKDFLPKMEDGTLQAGPGGARGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVTRHPSFDEESHYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYVLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTAATVGISREHAKVFNYGRIYGAGQSFAERLLMQFNHRLSRQEAADKAQQMYAVTKGLRRYRLSDDGEWLVKQLNVPVDRTEDGWVSLQDLRKIRREASRKSRWKKWEVVTERAWTGGTESEMFNKLESIAMSDTPRTPVLGCCISRALEPSVVQGEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDQCLRKEVTMDCKTPSNPTGMERKYGIPQGEALDIYQIIELTKGSLEKRSQPGP

Target ORF information:

RefSeq Version	NM_053528.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus DNA polymerase gamma, catalytic subunit (Polg), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053528.1

ORF Insert Sequence:

ATGAGCCGCC TGCTCTGGAA GAAGGTGGCC GGCGCCAAAG TCGCCTCAGG GCCAGTACCA 
GCAACAGGAC GCTGGGTCTC CAGCTCCGTC CTCGACCCCG TCCCCAGCGA CGGGCAGCCG 
CAGTCGCAAA TGCCCTCCTC AGAGAATGGG CAGCTGCGGC TCAACCCTCT GCACATCCAG 
ATGCTGTCGA GAGGCCTGCA CGAGCAAATC TTCGGGTGCG GAGGGGACGT GCCCGACGAG 
GCCGCGGTGC AGCGCAGCAT CGAGCACCTA CGGAAGCACG GGCTCTGGGG GCAGCCGACC 
ACGCCCTTGC CAGACGTGCA GCTGCGCCTG CCCCGGCTCT TCGGGGGCAA CCTGGACCAG 
CACTTCCGCC TCCTGGCCCA GAAGCAGAGC CTCCCGTACT TGGAGGCGGC CGCCTCGTTA 
TCGGAGGCCC AATTGCCCCC CCAGCCCAGG AAGTGGGTCT GGGCGGAGGG CTGGACCCGG 
TACGGCCCCG AGGGGGAGGC CGAACCCGTG GCCATCCCCG AGGAGCGGGC CCTGGTGTTC 
GACGTGGAGG TCTGCTTGGC AGAGGGAACC TGCCCCACTT TGGCGGTGGC CATATCCCCC 
TCGGCCTGGT ATTCCTGGTG CAGCCGGCGG CTGGTGGAAG AGCGTTACTC TTGGACCAGC 
CAGCTGTCGC CGGCTGACCT AATCCCTTTG GGGGTCTCTG CTAGTGCCAG CAGCTCCACC 
CAGCAGGATT GGCAGGAACA GTTAGTGGTG GGGCACAATG TTTCCTTTGA CCGAGCCCAT 
ATCAGGGAGC AGTATCTGAT TCAGGGCTCA CGCATGCACT TTCTGGACAC TATGAGCATG 
CACATGGCTA TCTCAGGGCT GAGCAGCTTC CAGCGCAGTC TGTGGATGGG AGCCAAGCAG 
GGCAAGCACA AGACCCAGCA TCCTACAAAG CGAGGTCAGA AGTCCCAGAA GAATGCGAAT 
GGTCCAGCGA TTTCATCTTG GGACTGGATG GACATCAGCA GTGCTAATAA TCTTGCAGAC 
GTGCACAACC TTTATGTGGG GGGACCTCGC TTAGCGAAGG AGCCTCGGGA ACTGTTCGTC 
AAAGGCAGCA TGAGGGATAT CAGGGAGAAC TTCCAGGATC TGATGGAGTA CTGTGCTCGT 
GATGTGTGGG CCACCTTTGA GGTTTTCCAG CAGCAGCTGC CGCTCTTCTT GGAGAGGTGT 
CCCCACCCAG TGACTCTGGC TGGCATGCTG GAGATGGGTG TCTCCTACCT GCCTGTCAAC 
CAGAACTGGG AGCGGTACCT GACAGAGGCA CAGAGCACAT ATGAGGAACT CCAGCGGGAG 
ATGAAGAAGT CGCTGATGGA GCTGGCTAAT GATGCCTGCC AGTTGCTCTC AGGAGAGAGG 
TACAAAGAAG ACCCTTGGCT CTGGGACCTA GAATGGGACT TGCAGGAATT TAAGCAGAAA 
AAGGCAAAGA AGGTGAAGAA GACAGCCTCA GCCAGCAAGT TGCCCATCGA GGGAGCTGGG 
CCCTTTGGGG ATCCCATGGA TCAGGAAGAT CCTGGACCAC CCAGTGAGGA GGAGGAGCTT 
CAGCAAAATA TAATGGCCCA CACCCGTTTA CAGCAGCTGA AGAGCACCAC AGACCTCCTG 
CCTAAGCGAC CCCAACACCT TCCTGGACAC CCTGGGTGGT ACCGGAAACT CTGCCCTCGG 
CTAGATGACC CTGCATGGAC TCCGGGCCCC AGCCTCCTCA GCCTGCAAAT GCGGGTCACT 
CCTAAGCTCA TGGCACTGAC CTGGGATGGT TTTCCTCTAC ACTACTCAGA CTCTCATGGT 
TGGGGCTACC TGGTGCCTGG GCGGCGGGAT AATCTGACTG AGCTGCCAGT GAGCCCCACT 
GAGGAGTCAG CTGCGGTGAC CTGCCCCTAC AGAGCCATCG AGTCCTTGTA CAGGAGGCAC 
TGTCTTGACC AGGGCAAGCA GCAGCTGGAG ACCCAGGAGA CAGACCTGGC TGAGGAGTTC 
TTGCTCACGG ACAGTGCCAT GTGGCAGACG GTAGAAGAAC TGGGCTGCTT AGATGTGGAG 
GCTGAGGCCA CAGTGGAGAG TTCAGGGCTG AGTCAGCCCC TAGTTCCGCC TACTGCTTGT 
GCCCCCAAAA CCAGCCAGCC CACTTATCAC CATGGCAACG GACCTTATAA TGATGTGGAT 
ATCCCCGGTT GCTGGTTTTT CAAGCTGCCT CACAAGGATG GTAACAACTA CAATGTGGGT 
AGTCCCTTTG CCAAAGATTT CCTGCCCAAG ATGGAAGACG GCACTCTGCA GGCTGGCCCA 
GGGGGTGCCA GGGGACCTCG TGCCCTGGAA ATAAATAAAA TGATTTCTTT TTGGAGGAAT 
GCTCATAAAC GCATCAGCTC CCAGATGGTG GTATGGCTCC CCAGGTCAGC TCTGCCCCGG 
GCTGTGACCA GGCACCCCAG CTTTGATGAG GAAAGCCACT ATGGGGCCAT CCTGCCCCAG 
GTGGTGACTG CTGGCACCAT CACCCGTCGC GCTGTGGAGC CCACGTGGCT CACTGCCAGC 
AATGCTCGGC CTGACCGGGT AGGCAGTGAG TTGAAAGCCA TGGTGCAGGC TCCACCTGGC 
TATGTCCTTG TGGGTGCTGA TGTGGACTCA CAGGAACTGT GGATCGCAGC CGTTCTTGGA 
GATGCTCACT TTGCTGGGAT GCATGGCTGC ACGGCCTTTG GCTGGATGAC TCTTCAGGGC 
AGGAAGAGCA GAGGCACTGA TCTGCACAGT AAGACAGCCG CCACTGTGGG CATCAGTCGT 
GAGCACGCCA AAGTCTTCAA CTACGGCCGC ATCTACGGGG CTGGGCAGTC CTTTGCCGAG 
CGCCTGCTGA TGCAGTTCAA CCACAGGCTC TCAAGGCAGG AGGCAGCTGA CAAGGCCCAG 
CAGATGTACG CTGTCACGAA AGGCCTGCGC CGATACCGGC TCTCAGATGA TGGTGAATGG 
CTGGTGAAAC AGTTAAATGT TCCTGTGGAC AGGACAGAAG ACGGCTGGGT TTCCCTACAA 
GATCTTCGAA AGATCCGAAG AGAAGCTTCA AGGAAGTCTC GATGGAAGAA GTGGGAGGTA 
GTCACTGAAC GAGCATGGAC AGGGGGTACG GAGTCAGAAA TGTTTAATAA GCTGGAGAGC 
ATTGCCATGT CTGACACACC ACGCACCCCA GTGCTGGGCT GCTGCATCAG CAGAGCCTTG 
GAGCCCTCGG TTGTCCAGGG AGAGTTTATG ACCAGTCGTG TGAATTGGGT GGTACAGAGC 
TCTGCTGTGG ACTACTTACA CCTCATGCTT GTGGCCATGA AGTGGCTGTT TGAGGAATTT 
GCCATTGATG GGCGCTTCTG CATCAGCATC CATGATGAGG TGCGCTACCT GGTACGTGAG 
GAGGACCGCT ACCGTGCTGC CCTGGCACTG CAGATCACCA ATCTCCTGAC CAGGTGCATG 
TTTGCCTACA AGCTGGGTCT GAATGACCTG CCCCAGTCAG TTGCCTTTTT CAGTGCAGTA 
GACATTGACC AGTGCCTCAG GAAGGAAGTG ACCATGGACT GTAAAACTCC TTCTAACCCA 
ACTGGGATGG AAAGGAAATA CGGGATTCCC CAGGGTGAAG CACTGGATAT TTACCAGATA 
ATTGAACTCA CCAAAGGCTC CTTGGAAAAA CGAAGCCAGC CTGGACCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Polg ( XM_006229410.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006229472.1 Rattus norvegicus polymerase (DNA) gamma, catalytic subunit (Polg), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa22925
Clone ID Related Accession (Same CDS sequence)	XM_006229410.3
Accession Version	XM_006229410.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3651bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	DNA polymerase subunit gamma-1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006229410.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCCGCC TGCTCTGGAA GAAGGTGGCC GGCGCCAAAG TCGCCTCAGG GCCAGTACCA 
GCAACAGGAC GCTGGGTCTC CAGCTCCGTC CTCGACCCCG TCCCCAGCGA CGGGCAGCCG 
CAGTCGCAAA TGCCCTCCTC AGAGAATGGG CAGCTGCGGC TCAACCCTCT GCACATCCAG 
ATGCTGTCGA GAGGCCTGCA CGAGCAAATC TTCGGGTGCG GAGGGGACGT GCCCGACGAG 
GCCGCGGTGC AGCGCAGCAT CGAGCACCTG CGGAAGCACG GGCTCTGGGG GCAGCCGACC 
ACGCCCTTGC CAGACGTGCA GCTGCGCCTG CCCCGGCTCT TCGGGGGCAA CCTGGACCAG 
CACTTCCGCC TCCTGGCCCA GAAGCAGAGC CTCCCGTACT TGGAGGCGGC CGCCTCGTTA 
TCGGAGGCCC AATTGCCCCC CCAGCCCAGG AAGTGGGTCT GGGCGGAGGG CTGGACCCGG 
TACGGCCCCG AGGGGGAGGC CGAACCCGTG GCCATCCCCG AGGAGCGGGC CCTGGTGTTC 
GACGTGGAGG TCTGCTTGGC AGAGGGAACC TGCCCCACTT TGGCGGTGGC CATATCCCCC 
TCGGCCTGGT ATTCCTGGTG CAGCCGGCGG CTGGTGGAAG AGCGTTACTC TTGGACCAGC 
CAGCTGTCGC CGGCTGACCT AATCCCTTTG GGGGTCTCTG CTAGTGCCAG CAGCTCCACC 
CAGCAGGATT GGCAGGAACA GTTAGTGGTG GGGCACAATG TTTCCTTTGA CCGAGCCCAT 
ATCAGGGAGC AGTATCTGAT TCAGGGCTCA CGCATGCGCT TTCTGGACAC TATGAGCATG 
CACATGGCTA TCTCAGGGCT GAGCAGCTTC CAGCGCAGTC TGTGGATGGG AGCCAAGCAG 
GGCAAGCACA AGACCCAGCA TCCTACAAAG CGAGGTCAGA AGTCCCAGAA GAATGCGAAT 
GGTCCAGCGA TTTCATCTTG GGACTGGATG GACATCAGCA GTGCTAATAA TCTTGCAGAC 
GTGCACAACC TTTATGTGGG GGGACCTCGC TTAGCGAAGG AGCCTCGGGA ACTGTTCGTC 
AAAGGCAGCA TGAGGGATAT CAGGGAGAAC TTCCAGGATC TGATGGAGTA CTGTGCTCGT 
GATGTGTGGG CCACCTTTGA GGTTTTCCAG CAGCAGCTGC CGCTCTTCTT GGAGAGGTGT 
CCCCACCCAG TGACTCTGGC TGGCATGCTG GAGATGGGTG TCTCCTACCT GCCTGTCAAC 
CAGAACTGGG AGCGGTACCT GACAGAAGCA CAGAGCACAT ATGAGGAACT CCAGCGGGAG 
ATGAAGAAGT CGCTGATGGA GCTGGCTAAT GACGCCTGCC AGTTGCTCTC AGGAGAGAGG 
TACAAAGAAG ACCCTTGGCT CTGGGACCTA GAATGGGACT TGCAGGAATT TAAGCAGAAA 
AAGGCAAAGA AGGTGAAGAA GACAGCCTCA GCCAGCAAGT TGCCCATCGA GGGAGCTGGG 
CCCTTTGGGG ATCCCATGGA TCAGGAAGAT CCTGGACCAC CCAGTGAGGA GGAGGAGCTT 
CAGCAAAATA TAATGGCCCA CACCCGTTTA CAGCAGCTGA AGAGCACCAC AGACCTCCTG 
CCTAAGCGAC CCCAACACCT TCCTGGACAC CCTGGGTGGT ACCGGAAACT CTGCCCTCGG 
CTAGATGACC CTGCATGGAC TCCGGGCCCC AGCCTCCTCA GCCTGCAAAT GCGGGTCACT 
CCTAAGCTCA TGGCACTGAC CTGGGATGGT TTTCCTCTAC ACTACTCAGA CTCTCATGGT 
TGGGGCTACC TGGTGCCTGG GCGGCGGGAT AATCTGACTG AGCTGCCAGT GAGCCCCACT 
GAGGAGTCAG CTGCGGTGAC CTGCCCCTAC AGAGCCATCG AGTCCTTGTA CAGGAGGCAC 
TGTCTTGACC AGGGCAAGCA GCAGCTGGAG ACCCAGGAGA CAGACCTGGC TGAGGAGTTC 
TTGCTCACGG ACAGTGCCAT GTGGCAGACG GTAGAAGAAC TGGGCTGCTT AGATGTGGAG 
GCTGAGGCCA CAGTGGAGAG TTCAGGGCTG AGTCAGCCCC TAGTTCCGCC TACTGCTTGT 
GCCCCCAAAA CCAGCCAGCC CACTTATCAC CATGGCAACG GACCTTATAA TGATGTGGAT 
ATCCCCGGTT GCTGGTTTTT CAAGCTGCCT CACAAGGATG GTAACAACTA CAATGTGGGT 
AGTCCCTTTG CCAAAGATTT CCTGCCCAAG ATGGAAGACG GCACTCTGCA GGCTGGCCCA 
GGGGGTGCCA GGGGACCTCG TGCCCTGGAA ATAAATAAAA TGATTTCTTT TTGGAGGAAT 
GCTCATAAAC GCATCAGCTC CCAGATGGTG GTATGGCTCC CCAGGTCAGC TCTGCCCCGG 
GCTGTGACCA GGCACCCCAG CTTTGATGAG GAAAGCCACT ATGGGGCCAT CCTGCCCCAG 
GTGGTGACTG CTGGCACCAT CACCCGTCGC GCTGTGGAGC CCACGTGGCT CACCGCCAGC 
AATGCTCGGC CTGACCGGGT AGGCAGTGAG TTGAAAGCCA TGGTGCAGGC TCCACCTGGC 
TATGTCCTTG TGGGTGCTGA TGTGGACTCA CAGGAACTGT GGATCGCAGC CGTTCTTGGA 
GATGCTCACT TTGCTGGGAT GCATGGCTGC ACGGCCTTTG GCTGGATGAC TCTTCAGGGC 
AGGAAGAGCA GAGGCACTGA TCTGCACAGT AAGACAGCCG CCACTGTGGG CATCAGTCGT 
GAGCACGCCA AAGTCTTCAA CTACGGCCGC ATCTACGGGG CTGGGCAGTC CTTTGCCGAG 
CGCCTGCTGA TGCAGTTCAA CCACAGGCTC TCAAGGCAGG AGGCAGCTGA CAAGGCCCAG 
CAGATGTACG CTGTCACGAA AGGCCTGCGC CGATACCGGC TCTCAGATGA TGGTGAATGG 
CTGGTGAAAC AGTTAAATGT TCCTGTGGAC AGGACAGAAG ACGGCTGGGT TTCCCTACAA 
GATCTTCGAA AGATCCGAAG AGAAGCTTCA AGGAAGTCTC GATGGAAGAA GTGGGAGGTA 
GTCACTGAAC GAGCATGGAC AGGGGGTACG GAGTCAGAAA TGTTTAATAA GCTGGAGAGC 
ATTGCCATGT CTGACACACC ACGCACCCCA GTGCTGGGCT GCTGCATCAG CAGAGCCTTG 
GAGCCCTCGG TTGTCCAGGG AGAGTTTATG ACCAGTCGTG TGAATTGGGT GGTACAGAGC 
TCTGCTGTGG ACTACTTACA CCTCATGCTT GTGGCCATGA AGTGGCTGTT TGAGGAATTT 
GCCATTGATG GGCGCTTCTG CATCAGCATC CATGATGAGG TGCGCTACCT GGTACGTGAG 
GAGGACCGCT ACCGTGCTGC CCTGGCACTG CAGATCACCA ATCTCCTGAC CAGGTGCATG 
TTTGCCTACA AGCTGGGTCT GAATGACCTG CCCCAGTCAG TTGCCTTTTT CAGTGCAGTA 
GACATTGACC AGTGCCTCAG GAAGGAAGTG ACCATGGACT GTAAAACTCC TTCTAACCCA 
ACTGGGATGG AAAGGAAATA CGGGATTCCC CAGGGTGAAG CACTGGATAT TTACCAGATA 
ATTGAACTCA CCAAAGGCTC CTTGGAAAAA CGAAGCCAGC CTGGACCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006229472.1
CDS	339..3989
Translation	MSRLLWKKVAGAKVASGPVPATGRWVSSSVLDPVPSDGQPQSQMPSSENGQLRLNPLHIQMLSRGLHEQIFGCGGDVPDEAAVQRSIEHLRKHGLWGQPTTPLPDVQLRLPRLFGGNLDQHFRLLAQKQSLPYLEAAASLSEAQLPPQPRKWVWAEGWTRYGPEGEAEPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSRRLVEERYSWTSQLSPADLIPLGVSASASSSTQQDWQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWMGAKQGKHKTQHPTKRGQKSQKNANGPAISSWDWMDISSANNLADVHNLYVGGPRLAKEPRELFVKGSMRDIRENFQDLMEYCARDVWATFEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLTEAQSTYEELQREMKKSLMELANDACQLLSGERYKEDPWLWDLEWDLQEFKQKKAKKVKKTASASKLPIEGAGPFGDPMDQEDPGPPSEEEELQQNIMAHTRLQQLKSTTDLLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSDSHGWGYLVPGRRDNLTELPVSPTEESAAVTCPYRAIESLYRRHCLDQGKQQLETQETDLAEEFLLTDSAMWQTVEELGCLDVEAEATVESSGLSQPLVPPTACAPKTSQPTYHHGNGPYNDVDIPGCWFFKLPHKDGNNYNVGSPFAKDFLPKMEDGTLQAGPGGARGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVTRHPSFDEESHYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYVLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTAATVGISREHAKVFNYGRIYGAGQSFAERLLMQFNHRLSRQEAADKAQQMYAVTKGLRRYRLSDDGEWLVKQLNVPVDRTEDGWVSLQDLRKIRREASRKSRWKKWEVVTERAWTGGTESEMFNKLESIAMSDTPRTPVLGCCISRALEPSVVQGEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDQCLRKEVTMDCKTPSNPTGMERKYGIPQGEALDIYQIIELTKGSLEKRSQPGP

Target ORF information:

RefSeq Version	XM_006229410.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus polymerase (DNA) gamma, catalytic subunit (Polg), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006229410.3

ORF Insert Sequence:

ATGAGCCGCC TGCTCTGGAA GAAGGTGGCC GGCGCCAAAG TCGCCTCAGG GCCAGTACCA 
GCAACAGGAC GCTGGGTCTC CAGCTCCGTC CTCGACCCCG TCCCCAGCGA CGGGCAGCCG 
CAGTCGCAAA TGCCCTCCTC AGAGAATGGG CAGCTGCGGC TCAACCCTCT GCACATCCAG 
ATGCTGTCGA GAGGCCTGCA CGAGCAAATC TTCGGGTGCG GAGGGGACGT GCCCGACGAG 
GCCGCGGTGC AGCGCAGCAT CGAGCACCTG CGGAAGCACG GGCTCTGGGG GCAGCCGACC 
ACGCCCTTGC CAGACGTGCA GCTGCGCCTG CCCCGGCTCT TCGGGGGCAA CCTGGACCAG 
CACTTCCGCC TCCTGGCCCA GAAGCAGAGC CTCCCGTACT TGGAGGCGGC CGCCTCGTTA 
TCGGAGGCCC AATTGCCCCC CCAGCCCAGG AAGTGGGTCT GGGCGGAGGG CTGGACCCGG 
TACGGCCCCG AGGGGGAGGC CGAACCCGTG GCCATCCCCG AGGAGCGGGC CCTGGTGTTC 
GACGTGGAGG TCTGCTTGGC AGAGGGAACC TGCCCCACTT TGGCGGTGGC CATATCCCCC 
TCGGCCTGGT ATTCCTGGTG CAGCCGGCGG CTGGTGGAAG AGCGTTACTC TTGGACCAGC 
CAGCTGTCGC CGGCTGACCT AATCCCTTTG GGGGTCTCTG CTAGTGCCAG CAGCTCCACC 
CAGCAGGATT GGCAGGAACA GTTAGTGGTG GGGCACAATG TTTCCTTTGA CCGAGCCCAT 
ATCAGGGAGC AGTATCTGAT TCAGGGCTCA CGCATGCGCT TTCTGGACAC TATGAGCATG 
CACATGGCTA TCTCAGGGCT GAGCAGCTTC CAGCGCAGTC TGTGGATGGG AGCCAAGCAG 
GGCAAGCACA AGACCCAGCA TCCTACAAAG CGAGGTCAGA AGTCCCAGAA GAATGCGAAT 
GGTCCAGCGA TTTCATCTTG GGACTGGATG GACATCAGCA GTGCTAATAA TCTTGCAGAC 
GTGCACAACC TTTATGTGGG GGGACCTCGC TTAGCGAAGG AGCCTCGGGA ACTGTTCGTC 
AAAGGCAGCA TGAGGGATAT CAGGGAGAAC TTCCAGGATC TGATGGAGTA CTGTGCTCGT 
GATGTGTGGG CCACCTTTGA GGTTTTCCAG CAGCAGCTGC CGCTCTTCTT GGAGAGGTGT 
CCCCACCCAG TGACTCTGGC TGGCATGCTG GAGATGGGTG TCTCCTACCT GCCTGTCAAC 
CAGAACTGGG AGCGGTACCT GACAGAAGCA CAGAGCACAT ATGAGGAACT CCAGCGGGAG 
ATGAAGAAGT CGCTGATGGA GCTGGCTAAT GACGCCTGCC AGTTGCTCTC AGGAGAGAGG 
TACAAAGAAG ACCCTTGGCT CTGGGACCTA GAATGGGACT TGCAGGAATT TAAGCAGAAA 
AAGGCAAAGA AGGTGAAGAA GACAGCCTCA GCCAGCAAGT TGCCCATCGA GGGAGCTGGG 
CCCTTTGGGG ATCCCATGGA TCAGGAAGAT CCTGGACCAC CCAGTGAGGA GGAGGAGCTT 
CAGCAAAATA TAATGGCCCA CACCCGTTTA CAGCAGCTGA AGAGCACCAC AGACCTCCTG 
CCTAAGCGAC CCCAACACCT TCCTGGACAC CCTGGGTGGT ACCGGAAACT CTGCCCTCGG 
CTAGATGACC CTGCATGGAC TCCGGGCCCC AGCCTCCTCA GCCTGCAAAT GCGGGTCACT 
CCTAAGCTCA TGGCACTGAC CTGGGATGGT TTTCCTCTAC ACTACTCAGA CTCTCATGGT 
TGGGGCTACC TGGTGCCTGG GCGGCGGGAT AATCTGACTG AGCTGCCAGT GAGCCCCACT 
GAGGAGTCAG CTGCGGTGAC CTGCCCCTAC AGAGCCATCG AGTCCTTGTA CAGGAGGCAC 
TGTCTTGACC AGGGCAAGCA GCAGCTGGAG ACCCAGGAGA CAGACCTGGC TGAGGAGTTC 
TTGCTCACGG ACAGTGCCAT GTGGCAGACG GTAGAAGAAC TGGGCTGCTT AGATGTGGAG 
GCTGAGGCCA CAGTGGAGAG TTCAGGGCTG AGTCAGCCCC TAGTTCCGCC TACTGCTTGT 
GCCCCCAAAA CCAGCCAGCC CACTTATCAC CATGGCAACG GACCTTATAA TGATGTGGAT 
ATCCCCGGTT GCTGGTTTTT CAAGCTGCCT CACAAGGATG GTAACAACTA CAATGTGGGT 
AGTCCCTTTG CCAAAGATTT CCTGCCCAAG ATGGAAGACG GCACTCTGCA GGCTGGCCCA 
GGGGGTGCCA GGGGACCTCG TGCCCTGGAA ATAAATAAAA TGATTTCTTT TTGGAGGAAT 
GCTCATAAAC GCATCAGCTC CCAGATGGTG GTATGGCTCC CCAGGTCAGC TCTGCCCCGG 
GCTGTGACCA GGCACCCCAG CTTTGATGAG GAAAGCCACT ATGGGGCCAT CCTGCCCCAG 
GTGGTGACTG CTGGCACCAT CACCCGTCGC GCTGTGGAGC CCACGTGGCT CACCGCCAGC 
AATGCTCGGC CTGACCGGGT AGGCAGTGAG TTGAAAGCCA TGGTGCAGGC TCCACCTGGC 
TATGTCCTTG TGGGTGCTGA TGTGGACTCA CAGGAACTGT GGATCGCAGC CGTTCTTGGA 
GATGCTCACT TTGCTGGGAT GCATGGCTGC ACGGCCTTTG GCTGGATGAC TCTTCAGGGC 
AGGAAGAGCA GAGGCACTGA TCTGCACAGT AAGACAGCCG CCACTGTGGG CATCAGTCGT 
GAGCACGCCA AAGTCTTCAA CTACGGCCGC ATCTACGGGG CTGGGCAGTC CTTTGCCGAG 
CGCCTGCTGA TGCAGTTCAA CCACAGGCTC TCAAGGCAGG AGGCAGCTGA CAAGGCCCAG 
CAGATGTACG CTGTCACGAA AGGCCTGCGC CGATACCGGC TCTCAGATGA TGGTGAATGG 
CTGGTGAAAC AGTTAAATGT TCCTGTGGAC AGGACAGAAG ACGGCTGGGT TTCCCTACAA 
GATCTTCGAA AGATCCGAAG AGAAGCTTCA AGGAAGTCTC GATGGAAGAA GTGGGAGGTA 
GTCACTGAAC GAGCATGGAC AGGGGGTACG GAGTCAGAAA TGTTTAATAA GCTGGAGAGC 
ATTGCCATGT CTGACACACC ACGCACCCCA GTGCTGGGCT GCTGCATCAG CAGAGCCTTG 
GAGCCCTCGG TTGTCCAGGG AGAGTTTATG ACCAGTCGTG TGAATTGGGT GGTACAGAGC 
TCTGCTGTGG ACTACTTACA CCTCATGCTT GTGGCCATGA AGTGGCTGTT TGAGGAATTT 
GCCATTGATG GGCGCTTCTG CATCAGCATC CATGATGAGG TGCGCTACCT GGTACGTGAG 
GAGGACCGCT ACCGTGCTGC CCTGGCACTG CAGATCACCA ATCTCCTGAC CAGGTGCATG 
TTTGCCTACA AGCTGGGTCT GAATGACCTG CCCCAGTCAG TTGCCTTTTT CAGTGCAGTA 
GACATTGACC AGTGCCTCAG GAAGGAAGTG ACCATGGACT GTAAAACTCC TTCTAACCCA 
ACTGGGATGG AAAGGAAATA CGGGATTCCC CAGGGTGAAG CACTGGATAT TTACCAGATA 
ATTGAACTCA CCAAAGGCTC CTTGGAAAAA CGAAGCCAGC CTGGACCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Polg ( XM_008759561.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008757783.1 Rattus norvegicus polymerase (DNA) gamma, catalytic subunit (Polg), transcript variant X1, mRNA.

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CloneID	ORa43879
Clone ID Related Accession (Same CDS sequence)	XM_008759561.2
Accession Version	XM_008759561.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3672bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	DNA polymerase subunit gamma-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008759561.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCCGCC TGCTCTGGAA GAAGGTGGCC GGCGCCAAAG TCGCCTCAGG GCCAGTACCA 
GCAACAGGAC GCTGGGTCTC CAGCTCCGTC CTCGACCCCG TCCCCAGCGA CGGGCAGCCG 
CAGTCGCAAA TGCCCTCCTC AGAGAATGGG CAGCTGCGGC TCAACCCTCT GCACATCCAG 
ATGCTGTCGA GAGGCCTGCA CGAGCAAATC TTCGGGTGCG GAGGGGACGT GCCCGACGAG 
GCCGCGGTGC AGCGCAGCAT CGAGCACCTG CGGAAGCACG GGCTCTGGGG GCAGCCGACC 
ACGCCCTTGC CAGACGTGCA GCTGCGCCTG CCCCGGCTCT TCGGGGGCAA CCTGGACCAG 
CACTTCCGCC TCCTGGCCCA GAAGCAGAGC CTCCCGTACT TGGAGGCGGC CGCCTCGTTA 
TCGGAGGCCC AATTGCCCCC CCAGCCCAGG AAGTGGGTCT GGGCGGAGGG CTGGACCCGG 
TACGGCCCCG AGGGGGAGGC CGAACCCGTG GCCATCCCCG AGGAGCGGGC CCTGGTGTTC 
GACGTGGAGG TCTGCTTGGC AGAGGGAACC TGCCCCACTT TGGCGGTGGC CATATCCCCC 
TCGGCCTGGT ATTCCTGGTG CAGCCGGCGG CTGGTGGAAG AGCGTTACTC TTGGACCAGC 
CAGCTGTCGC CGGCTGACCT AATCCCTTTG GGGGTCTCTG CTAGTGCCAG CAGCTCCACC 
CAGCAGGATT GGCAGGAACA GTTAGTGGTG GGGCACAATG TTTCCTTTGA CCGAGCCCAT 
ATCAGGGAGC AGTATCTGAT TCAGGGCTCA CGCATGCGCT TTCTGGACAC TATGAGCATG 
CACATGGCTA TCTCAGGGCT GAGCAGCTTC CAGCGCAGTC TGTGGATGGG AGCCAAGCAG 
GGCAAGCACA AGACCCAGCA TCCTACAAAG CGAGGTCAGA AGTCCCAGAA GAATGCGAAT 
GGTCCAGCGA TTTCATCTTG GGACTGGATG GACATCAGCA GTGCTAATAA TCTTGCAGAC 
GTGCACAACC TTTATGTGGG GGGACCTCGC TTAGCGAAGG AGCCTCGGGA ACTGTTCGTC 
AAAGGCAGCA TGAGGGATAT CAGGGAGAAC TTCCAGGATC TGATGGAGTA CTGTGCTCGT 
GATGTGTGGG CCACCTTTGA GGTTTTCCAG CAGCAGCTGC CGCTCTTCTT GGAGAGGTGT 
CCCCACCCAG TGACTCTGGC TGGCATGCTG GAGATGGGTG TCTCCTACCT GCCTGTCAAC 
CAGAACTGGG AGCGGTACCT GACAGAAGCA CAGAGCACAT ATGAGGAACT CCAGCGGGAG 
ATGAAGAAGT CGCTGATGGA GCTGGCTAAT GACGCCTGCC AGTTGCTCTC AGGAGAGAGC 
CTGGTGGACT GGCTCTACAG GTACAAAGAA GACCCTTGGC TCTGGGACCT AGAATGGGAC 
TTGCAGGAAT TTAAGCAGAA AAAGGCAAAG AAGGTGAAGA AGACAGCCTC AGCCAGCAAG 
TTGCCCATCG AGGGAGCTGG GCCCTTTGGG GATCCCATGG ATCAGGAAGA TCCTGGACCA 
CCCAGTGAGG AGGAGGAGCT TCAGCAAAAT ATAATGGCCC ACACCCGTTT ACAGCAGCTG 
AAGAGCACCA CAGACCTCCT GCCTAAGCGA CCCCAACACC TTCCTGGACA CCCTGGGTGG 
TACCGGAAAC TCTGCCCTCG GCTAGATGAC CCTGCATGGA CTCCGGGCCC CAGCCTCCTC 
AGCCTGCAAA TGCGGGTCAC TCCTAAGCTC ATGGCACTGA CCTGGGATGG TTTTCCTCTA 
CACTACTCAG ACTCTCATGG TTGGGGCTAC CTGGTGCCTG GGCGGCGGGA TAATCTGACT 
GAGCTGCCAG TGAGCCCCAC TGAGGAGTCA GCTGCGGTGA CCTGCCCCTA CAGAGCCATC 
GAGTCCTTGT ACAGGAGGCA CTGTCTTGAC CAGGGCAAGC AGCAGCTGGA GACCCAGGAG 
ACAGACCTGG CTGAGGAGTT CTTGCTCACG GACAGTGCCA TGTGGCAGAC GGTAGAAGAA 
CTGGGCTGCT TAGATGTGGA GGCTGAGGCC ACAGTGGAGA GTTCAGGGCT GAGTCAGCCC 
CTAGTTCCGC CTACTGCTTG TGCCCCCAAA ACCAGCCAGC CCACTTATCA CCATGGCAAC 
GGACCTTATA ATGATGTGGA TATCCCCGGT TGCTGGTTTT TCAAGCTGCC TCACAAGGAT 
GGTAACAACT ACAATGTGGG TAGTCCCTTT GCCAAAGATT TCCTGCCCAA GATGGAAGAC 
GGCACTCTGC AGGCTGGCCC AGGGGGTGCC AGGGGACCTC GTGCCCTGGA AATAAATAAA 
ATGATTTCTT TTTGGAGGAA TGCTCATAAA CGCATCAGCT CCCAGATGGT GGTATGGCTC 
CCCAGGTCAG CTCTGCCCCG GGCTGTGACC AGGCACCCCA GCTTTGATGA GGAAAGCCAC 
TATGGGGCCA TCCTGCCCCA GGTGGTGACT GCTGGCACCA TCACCCGTCG CGCTGTGGAG 
CCCACGTGGC TCACCGCCAG CAATGCTCGG CCTGACCGGG TAGGCAGTGA GTTGAAAGCC 
ATGGTGCAGG CTCCACCTGG CTATGTCCTT GTGGGTGCTG ATGTGGACTC ACAGGAACTG 
TGGATCGCAG CCGTTCTTGG AGATGCTCAC TTTGCTGGGA TGCATGGCTG CACGGCCTTT 
GGCTGGATGA CTCTTCAGGG CAGGAAGAGC AGAGGCACTG ATCTGCACAG TAAGACAGCC 
GCCACTGTGG GCATCAGTCG TGAGCACGCC AAAGTCTTCA ACTACGGCCG CATCTACGGG 
GCTGGGCAGT CCTTTGCCGA GCGCCTGCTG ATGCAGTTCA ACCACAGGCT CTCAAGGCAG 
GAGGCAGCTG ACAAGGCCCA GCAGATGTAC GCTGTCACGA AAGGCCTGCG CCGATACCGG 
CTCTCAGATG ATGGTGAATG GCTGGTGAAA CAGTTAAATG TTCCTGTGGA CAGGACAGAA 
GACGGCTGGG TTTCCCTACA AGATCTTCGA AAGATCCGAA GAGAAGCTTC AAGGAAGTCT 
CGATGGAAGA AGTGGGAGGT AGTCACTGAA CGAGCATGGA CAGGGGGTAC GGAGTCAGAA 
ATGTTTAATA AGCTGGAGAG CATTGCCATG TCTGACACAC CACGCACCCC AGTGCTGGGC 
TGCTGCATCA GCAGAGCCTT GGAGCCCTCG GTTGTCCAGG GAGAGTTTAT GACCAGTCGT 
GTGAATTGGG TGGTACAGAG CTCTGCTGTG GACTACTTAC ACCTCATGCT TGTGGCCATG 
AAGTGGCTGT TTGAGGAATT TGCCATTGAT GGGCGCTTCT GCATCAGCAT CCATGATGAG 
GTGCGCTACC TGGTACGTGA GGAGGACCGC TACCGTGCTG CCCTGGCACT GCAGATCACC 
AATCTCCTGA CCAGGTGCAT GTTTGCCTAC AAGCTGGGTC TGAATGACCT GCCCCAGTCA 
GTTGCCTTTT TCAGTGCAGT AGACATTGAC CAGTGCCTCA GGAAGGAAGT GACCATGGAC 
TGTAAAACTC CTTCTAACCC AACTGGGATG GAAAGGAAAT ACGGGATTCC CCAGGGTGAA 
GCACTGGATA TTTACCAGAT AATTGAACTC ACCAAAGGCT CCTTGGAAAA ACGAAGCCAG 
CCTGGACCCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008757783.1
CDS	341..4012
Translation	MSRLLWKKVAGAKVASGPVPATGRWVSSSVLDPVPSDGQPQSQMPSSENGQLRLNPLHIQMLSRGLHEQIFGCGGDVPDEAAVQRSIEHLRKHGLWGQPTTPLPDVQLRLPRLFGGNLDQHFRLLAQKQSLPYLEAAASLSEAQLPPQPRKWVWAEGWTRYGPEGEAEPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSRRLVEERYSWTSQLSPADLIPLGVSASASSSTQQDWQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWMGAKQGKHKTQHPTKRGQKSQKNANGPAISSWDWMDISSANNLADVHNLYVGGPRLAKEPRELFVKGSMRDIRENFQDLMEYCARDVWATFEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLTEAQSTYEELQREMKKSLMELANDACQLLSGESLVDWLYRYKEDPWLWDLEWDLQEFKQKKAKKVKKTASASKLPIEGAGPFGDPMDQEDPGPPSEEEELQQNIMAHTRLQQLKSTTDLLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSDSHGWGYLVPGRRDNLTELPVSPTEESAAVTCPYRAIESLYRRHCLDQGKQQLETQETDLAEEFLLTDSAMWQTVEELGCLDVEAEATVESSGLSQPLVPPTACAPKTSQPTYHHGNGPYNDVDIPGCWFFKLPHKDGNNYNVGSPFAKDFLPKMEDGTLQAGPGGARGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVTRHPSFDEESHYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYVLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTAATVGISREHAKVFNYGRIYGAGQSFAERLLMQFNHRLSRQEAADKAQQMYAVTKGLRRYRLSDDGEWLVKQLNVPVDRTEDGWVSLQDLRKIRREASRKSRWKKWEVVTERAWTGGTESEMFNKLESIAMSDTPRTPVLGCCISRALEPSVVQGEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDQCLRKEVTMDCKTPSNPTGMERKYGIPQGEALDIYQIIELTKGSLEKRSQPGP

Target ORF information:

RefSeq Version	XM_008759561.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus polymerase (DNA) gamma, catalytic subunit (Polg), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008759561.2

ORF Insert Sequence:

ATGAGCCGCC TGCTCTGGAA GAAGGTGGCC GGCGCCAAAG TCGCCTCAGG GCCAGTACCA 
GCAACAGGAC GCTGGGTCTC CAGCTCCGTC CTCGACCCCG TCCCCAGCGA CGGGCAGCCG 
CAGTCGCAAA TGCCCTCCTC AGAGAATGGG CAGCTGCGGC TCAACCCTCT GCACATCCAG 
ATGCTGTCGA GAGGCCTGCA CGAGCAAATC TTCGGGTGCG GAGGGGACGT GCCCGACGAG 
GCCGCGGTGC AGCGCAGCAT CGAGCACCTG CGGAAGCACG GGCTCTGGGG GCAGCCGACC 
ACGCCCTTGC CAGACGTGCA GCTGCGCCTG CCCCGGCTCT TCGGGGGCAA CCTGGACCAG 
CACTTCCGCC TCCTGGCCCA GAAGCAGAGC CTCCCGTACT TGGAGGCGGC CGCCTCGTTA 
TCGGAGGCCC AATTGCCCCC CCAGCCCAGG AAGTGGGTCT GGGCGGAGGG CTGGACCCGG 
TACGGCCCCG AGGGGGAGGC CGAACCCGTG GCCATCCCCG AGGAGCGGGC CCTGGTGTTC 
GACGTGGAGG TCTGCTTGGC AGAGGGAACC TGCCCCACTT TGGCGGTGGC CATATCCCCC 
TCGGCCTGGT ATTCCTGGTG CAGCCGGCGG CTGGTGGAAG AGCGTTACTC TTGGACCAGC 
CAGCTGTCGC CGGCTGACCT AATCCCTTTG GGGGTCTCTG CTAGTGCCAG CAGCTCCACC 
CAGCAGGATT GGCAGGAACA GTTAGTGGTG GGGCACAATG TTTCCTTTGA CCGAGCCCAT 
ATCAGGGAGC AGTATCTGAT TCAGGGCTCA CGCATGCGCT TTCTGGACAC TATGAGCATG 
CACATGGCTA TCTCAGGGCT GAGCAGCTTC CAGCGCAGTC TGTGGATGGG AGCCAAGCAG 
GGCAAGCACA AGACCCAGCA TCCTACAAAG CGAGGTCAGA AGTCCCAGAA GAATGCGAAT 
GGTCCAGCGA TTTCATCTTG GGACTGGATG GACATCAGCA GTGCTAATAA TCTTGCAGAC 
GTGCACAACC TTTATGTGGG GGGACCTCGC TTAGCGAAGG AGCCTCGGGA ACTGTTCGTC 
AAAGGCAGCA TGAGGGATAT CAGGGAGAAC TTCCAGGATC TGATGGAGTA CTGTGCTCGT 
GATGTGTGGG CCACCTTTGA GGTTTTCCAG CAGCAGCTGC CGCTCTTCTT GGAGAGGTGT 
CCCCACCCAG TGACTCTGGC TGGCATGCTG GAGATGGGTG TCTCCTACCT GCCTGTCAAC 
CAGAACTGGG AGCGGTACCT GACAGAAGCA CAGAGCACAT ATGAGGAACT CCAGCGGGAG 
ATGAAGAAGT CGCTGATGGA GCTGGCTAAT GACGCCTGCC AGTTGCTCTC AGGAGAGAGC 
CTGGTGGACT GGCTCTACAG GTACAAAGAA GACCCTTGGC TCTGGGACCT AGAATGGGAC 
TTGCAGGAAT TTAAGCAGAA AAAGGCAAAG AAGGTGAAGA AGACAGCCTC AGCCAGCAAG 
TTGCCCATCG AGGGAGCTGG GCCCTTTGGG GATCCCATGG ATCAGGAAGA TCCTGGACCA 
CCCAGTGAGG AGGAGGAGCT TCAGCAAAAT ATAATGGCCC ACACCCGTTT ACAGCAGCTG 
AAGAGCACCA CAGACCTCCT GCCTAAGCGA CCCCAACACC TTCCTGGACA CCCTGGGTGG 
TACCGGAAAC TCTGCCCTCG GCTAGATGAC CCTGCATGGA CTCCGGGCCC CAGCCTCCTC 
AGCCTGCAAA TGCGGGTCAC TCCTAAGCTC ATGGCACTGA CCTGGGATGG TTTTCCTCTA 
CACTACTCAG ACTCTCATGG TTGGGGCTAC CTGGTGCCTG GGCGGCGGGA TAATCTGACT 
GAGCTGCCAG TGAGCCCCAC TGAGGAGTCA GCTGCGGTGA CCTGCCCCTA CAGAGCCATC 
GAGTCCTTGT ACAGGAGGCA CTGTCTTGAC CAGGGCAAGC AGCAGCTGGA GACCCAGGAG 
ACAGACCTGG CTGAGGAGTT CTTGCTCACG GACAGTGCCA TGTGGCAGAC GGTAGAAGAA 
CTGGGCTGCT TAGATGTGGA GGCTGAGGCC ACAGTGGAGA GTTCAGGGCT GAGTCAGCCC 
CTAGTTCCGC CTACTGCTTG TGCCCCCAAA ACCAGCCAGC CCACTTATCA CCATGGCAAC 
GGACCTTATA ATGATGTGGA TATCCCCGGT TGCTGGTTTT TCAAGCTGCC TCACAAGGAT 
GGTAACAACT ACAATGTGGG TAGTCCCTTT GCCAAAGATT TCCTGCCCAA GATGGAAGAC 
GGCACTCTGC AGGCTGGCCC AGGGGGTGCC AGGGGACCTC GTGCCCTGGA AATAAATAAA 
ATGATTTCTT TTTGGAGGAA TGCTCATAAA CGCATCAGCT CCCAGATGGT GGTATGGCTC 
CCCAGGTCAG CTCTGCCCCG GGCTGTGACC AGGCACCCCA GCTTTGATGA GGAAAGCCAC 
TATGGGGCCA TCCTGCCCCA GGTGGTGACT GCTGGCACCA TCACCCGTCG CGCTGTGGAG 
CCCACGTGGC TCACCGCCAG CAATGCTCGG CCTGACCGGG TAGGCAGTGA GTTGAAAGCC 
ATGGTGCAGG CTCCACCTGG CTATGTCCTT GTGGGTGCTG ATGTGGACTC ACAGGAACTG 
TGGATCGCAG CCGTTCTTGG AGATGCTCAC TTTGCTGGGA TGCATGGCTG CACGGCCTTT 
GGCTGGATGA CTCTTCAGGG CAGGAAGAGC AGAGGCACTG ATCTGCACAG TAAGACAGCC 
GCCACTGTGG GCATCAGTCG TGAGCACGCC AAAGTCTTCA ACTACGGCCG CATCTACGGG 
GCTGGGCAGT CCTTTGCCGA GCGCCTGCTG ATGCAGTTCA ACCACAGGCT CTCAAGGCAG 
GAGGCAGCTG ACAAGGCCCA GCAGATGTAC GCTGTCACGA AAGGCCTGCG CCGATACCGG 
CTCTCAGATG ATGGTGAATG GCTGGTGAAA CAGTTAAATG TTCCTGTGGA CAGGACAGAA 
GACGGCTGGG TTTCCCTACA AGATCTTCGA AAGATCCGAA GAGAAGCTTC AAGGAAGTCT 
CGATGGAAGA AGTGGGAGGT AGTCACTGAA CGAGCATGGA CAGGGGGTAC GGAGTCAGAA 
ATGTTTAATA AGCTGGAGAG CATTGCCATG TCTGACACAC CACGCACCCC AGTGCTGGGC 
TGCTGCATCA GCAGAGCCTT GGAGCCCTCG GTTGTCCAGG GAGAGTTTAT GACCAGTCGT 
GTGAATTGGG TGGTACAGAG CTCTGCTGTG GACTACTTAC ACCTCATGCT TGTGGCCATG 
AAGTGGCTGT TTGAGGAATT TGCCATTGAT GGGCGCTTCT GCATCAGCAT CCATGATGAG 
GTGCGCTACC TGGTACGTGA GGAGGACCGC TACCGTGCTG CCCTGGCACT GCAGATCACC 
AATCTCCTGA CCAGGTGCAT GTTTGCCTAC AAGCTGGGTC TGAATGACCT GCCCCAGTCA 
GTTGCCTTTT TCAGTGCAGT AGACATTGAC CAGTGCCTCA GGAAGGAAGT GACCATGGAC 
TGTAAAACTC CTTCTAACCC AACTGGGATG GAAAGGAAAT ACGGGATTCC CCAGGGTGAA 
GCACTGGATA TTTACCAGAT AATTGAACTC ACCAAAGGCT CCTTGGAAAA ACGAAGCCAG 
CCTGGACCCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Variants p.Q1236H and p.E1143G in mitochondrial DNA polymerase gamma POLG1 are not associated with increased risk for valproate-induced hepatotoxicity or pancreatic toxicity: A retrospective cohort study of patients with epilepsy.
Epilepsia59(11)2125-2136(2018 11)
Hynynen J,Pokka T,Komulainen-Ebrahim J,Myllynen P,Kärppä M,Pylvänen L,Kälviäinen R,Sokka A,Jyrkilä A,Lähdetie J,Haataja L,Mäkitalo A,Ylikotila P,Eriksson K,Haapala P,Ansakorpi H,Hinttala R,Vieira P,Majamaa K,Rantala H,Uusimaa J

Polymorphisms in POLG were associated with the prognosis and mtDNA content in hepatocellular carcinoma patients.
Bulletin du cancer104(6)500-507(2017 Jun)
Long X,Wang X,Chen Y,Guo X,Zhou F,Fan Y,Ge N,Guo M,Zhang Z,Dong G

Mitochondrial Single-stranded DNA-binding Proteins Stimulate the Activity of DNA Polymerase γ by Organization of the Template DNA.
The Journal of biological chemistry290(48)28697-707(2015 Nov)
Ciesielski GL,Bermek O,Rosado-Ruiz FA,Hovde SL,Neitzke OJ,Griffith JD,Kaguni LS

Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function.
Nucleic acids research42(21)13161-73(2014 Dec)
Szczesny B,Brunyanszki A,Olah G,Mitra S,Szabo C

Acute liver failure after valproate exposure in patients with POLG1 mutations and the prognosis after liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society20(11)1402-12(2014 Nov)
Hynynen J,Komulainen T,Tukiainen E,Nordin A,Arola J,Kälviäinen R,Jutila L,Röyttä M,Hinttala R,Majamaa K,Mäkisalo H,Uusimaa J

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Polg cDNA ORF clone, Rattus norvegicus(Norway rat)

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ORF Insert Sequence:

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