Apba1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Apba1
Entrez Gene ID	83589
Full Name	amyloid beta precursor protein binding family A member 1
Synonyms	Mint1
General protein information	Preferred Names amyloid beta precursor protein binding family A member 1 Names amyloid-beta A4 precursor protein-binding family A member 1 adapter protein X11alpha amyloid beta (A4) precursor protein-binding, family A, APBA1: amyloid beta (A4) precursor protein-binding, family A, member 1 (X11) amyloid beta (A4) precursor protein-binding, family A, member 1 mint-1 neuron-specific X11 protein neuronal Munc18-1-interacting protein 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q51
Summary	component of multimeric complex containing Munc18-1 and syntaxin; may mediate synaptic vesicle docking/fusion [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031779.2	NP_113967.1	amyloid-beta A4 precursor protein-binding family A member 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	APBA1	XP_001138890.1
Rattus norvegicus (Norway rat)	Apba1	NP_113967.1
Danio rerio (zebrafish)	apba1a	XP_001343372.1
Bos taurus (cattle)	APBA1	NP_001192743.1
Mus musculus (house mouse)	Apba1	NP_796008.2
Xenopus tropicalis (tropical clawed frog)	apba1	XP_004910830.1
Gallus gallus (chicken)	APBA1	XP_424829.2
Homo sapiens (human)	APBA1	NP_001154.2
Canis lupus familiaris (dog)	APBA1	XP_005615936.1

Gene Ontology
Bibliography

Related articles in PubMed

Scaffold protein X11α interacts with kalirin-7 in dendrites and recruits it to Golgi outposts.
Jones KA, Eng AG, Raval P, Srivastava DP, Penzes P
The Journal of biological chemistry289(51)35517-29(2014 Dec)

The INAD scaffold is a dynamic, redox-regulated modulator of signaling in the Drosophila eye.
Liu W, Wen W, Wei Z, Yu J, Ye F, Liu CH, Hardie RC, Zhang M
Cell145(7)1088-101(2011 Jun)

Cdk5 promotes synaptogenesis by regulating the subcellular distribution of the MAGUK family member CASK.
Samuels BA, Hsueh YP, Shu T, Liang H, Tseng HC, Hong CJ, Su SC, Volker J, Neve RL, Yue DT, Tsai LH
Neuron56(5)823-37(2007 Dec)

Reduction of mint-1, mint-2, and APP overexpression in okadaic acid-treated neurons.
Yoon S, Choi J, Haam J, Choe H, Kim D
Neuroreport18(18)1879-83(2007 Dec)

Genetic analysis of Mint/X11 proteins: essential presynaptic functions of a neuronal adaptor protein family.
Ho A, Morishita W, Atasoy D, Liu X, Tabuchi K, Hammer RE, Malenka RC, Südhof TC
The Journal of neuroscience : the official journal of the Society for Neuroscience26(50)13089-101(2006 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Apba1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Apba1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa08718	NM_031779.2 Latest version!	Rattus norvegicus amyloid beta precursor protein binding family A member 1 (Apba1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Apba1 ( NM_031779.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_113967.1 Rattus norvegicus amyloid beta precursor protein binding family A member 1 (Apba1), mRNA.

Price & Availability↑

CloneID	ORa08718
Clone ID Related Accession (Same CDS sequence)	NM_031779.2
Accession Version	NM_031779.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2520bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1568908800000
Organism	Rattus norvegicus(Norway rat)
Product	amyloid-beta A4 precursor protein-binding family A member 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF029105.1. On May 1, 2007 this sequence version replaced NM_031779.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF029105.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAACCACT TGGAGGGCTC CGCGGAGGTG GAGGTGGCCG ACGAGGCGCC AGGAGGGGAG 
GTGAACGAGT CCGTGGAGGC CGACCTGGAG CACCCCGAGG TGGAGGAAGA GCAGCAGCCG 
TCGCCCCCGC CGCCCGCAGG TCACGCACCC GAGGACCACC GCGCGCATCC GGCGCCGCCG 
CCGCCGCCAC CACCGCAGGA GGAGGAGGAG GAGCGCGGCG AGTGCCTGGC TCGCTCGGCC 
AGCACCGAGA GCGGCTTCCA CAACCACACG GACACCGCTG AGGGCGACGT GCTCGCCGCG 
GCCCGAGACG GCTACGAGGC GGAGCGCGCG CAGGACGCCG ACGATGAGAG CGCCTACGCC 
GTGCAGTACC GGCCCGAGGC CGAGGAGTAC ACGGAGCAGG CGGAGGCCGA GCACGCCGAG 
GCGGCGCAGC GGCGCGCGCT GCCCAACCAC CTGCACTTCC ACTCGCTGGA GCACGAGGAA 
GCCATGAACG CCGCCTACTC GGGCTATGTC TACACGCACC GGCTCTTCCA CCGCGCCGAG 
GACGAGCCCT ACGCCGAGCC CTACGCCGAC TACGGCGGCC TCCAGGAGCA CGTGTACGAG 
GAGATCGGGG ACGCGCCTGA GCTGGAGGCG CGCGACGGCC TGCGGCTCTA TGAGCGGGAG 
CGCGACGAGG CGGCCGCCTA CCGCCAGGAG GCCCTAGGCG CGCGGCTGCA CCACTACGAC 
GAGCGCTCCG ACGGCGAGTC CGACAGCCCC GAGAAGGAGG CGGAGTTCGC GCCCTACCCG 
CGCATGGACA GTTATGAGCA GGAAGAGGAC ATCGACCAGA TCGTGGCCGA GGTCAAGCAG 
AGCATGAGCT CGCAGAGCCT CGACAAGGCG GCCGAAGACA TGCCCGAGGC GGAGCAGGAC 
CTGGAGCGCG CCCCGACCCC GGGAGGGGGA CACCCCGACA GCCCTGGGCT GCCAGCACCT 
GCCGGGCAGC AGCAGCGAGT TGTGGGAACC CCGGGAGGCA GCGAGGTTGG TCAGCGGTAC 
AGCAAGGAAA AGAGGGATGC CATCTCGCTG GCCATCAAGG ACATCAAGGA GGCCATCGAA 
GAAGTGAAAA CCAGGACCAT CCGTTCGCCT TACACCCCCG ACGAACCCAA AGAGCCCATC 
TGGGTCATGC GCCAGGACAT TAGCCCCACA AGGGACTGTG ACGACCAGAG GCCCGTGGAC 
GGAGATTCTC CGTCTCCTGG CAGTTCCTCA CCCCTGGGTG CTGAGTCATC AATCACACCC 
CTTCATCCCG GTGACCCCAC GGAAGCCTCC ACTAATAAAG AGTCAAGAAA AAGCTTGGCT 
TCATTCCCAA CCTACGTTGA AGTTCCTGGA CCCTGCGACC CTGAAGACTT GATCGATGGA 
ATTATTTTTG CTGCCAATTA CCTTGGTTCC ACTCAGCTAC TCTCAGACAA AACTCCCTCC 
AAAAACGTGC GCATGATGCA GGCCCAGGAA GCAGTAAGCC GGATCAAGAC GGCCCAGAAA 
TTAGCCAAAA GCAGGAAGAA GGCTCCTGAA GGCGAATCTC AGCCAATGAC TGAGGTGGAC 
CTCTTCATCT CCACCCAGAG GATCAAAGTG TTGAATGCAG ATACACAGGA GCCTATGATG 
GACCACCCTC TGAGGACCAT TTCCTACATC GCAGACATTG GGAACATCGT CGTGCTGATG 
GCCCGCAGGC GGATGCCCCG CTCCAACTCC CAGGAGAATG TGGAGGCCTC TCACCCATCC 
CAGGATGCAA AACGGCAGTA CAAGATGATC TGTCATGTCT TTGAGTCTGA GGACGCCCAG 
CTGATCGCAC AGTCCATCGG GCAGGCCTTC AGCGTTGCAT ACCAGGAGTT CCTCAGGGCC 
AACGGGATTA ACCCAGAAGA CCTGAGCCAG AAGGAGTACA GCGACCTGCT CAACACCCAG 
GACATGTACA ACGATGACCT GATCCACTTC TCCAAGTCGG AAAACTGCAA AGATGTCTTC 
ATAGAGAAGC AGAAAGGAGA AATCCTGGGA GTTGTGATTG TGGAGTCTGG CTGGGGATCC 
ATTCTGCCAA CCGTGATCAT TGCCAACATG ATGCACGGAG GCCCCGCCGA GAAGTCGGGG 
AAGCTGAACA TCGGGGACCA GATCATGTCC ATTAACGGCA CCAGCCTGGT GGGCCTGCCC 
CTGTCCACCT GCCAGAGCAT CATTAAGGGC TTAAAGAACC AGTCCCGCGT GAAGCTGAAC 
ATCGTGAGGT GCCCCCCAGT GACCACAGTG CTAATTAGGA GGCCGGACCT TCGCTACCAG 
CTGGGTTTCA GCGTGCAGAA TGGAATTATC TGTAGCCTCA TGAGAGGGGG AATAGCTGAG 
AGAGGAGGTG TCCGCGTGGG ACATCGGATC ATTGAAATCA ACGGCCAGAG TGTCGTAGCC 
ACACCACACG AGAAGATCGT CCACATACTC TCCAATGCTG TTGGGGAGAT CCACATGAAG 
ACAATGCCAG CAGCCATGTA CAGACTGCTG ACAGCCCAGG AGCAGCCCGT TTACATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113967.1
CDS	342..2861
Translation	MNHLEGSAEVEVADEAPGGEVNESVEADLEHPEVEEEQQPSPPPPAGHAPEDHRAHPAPPPPPPPQEEEEERGECLARSASTESGFHNHTDTAEGDVLAAARDGYEAERAQDADDESAYAVQYRPEAEEYTEQAEAEHAEAAQRRALPNHLHFHSLEHEEAMNAAYSGYVYTHRLFHRAEDEPYAEPYADYGGLQEHVYEEIGDAPELEARDGLRLYERERDEAAAYRQEALGARLHHYDERSDGESDSPEKEAEFAPYPRMDSYEQEEDIDQIVAEVKQSMSSQSLDKAAEDMPEAEQDLERAPTPGGGHPDSPGLPAPAGQQQRVVGTPGGSEVGQRYSKEKRDAISLAIKDIKEAIEEVKTRTIRSPYTPDEPKEPIWVMRQDISPTRDCDDQRPVDGDSPSPGSSSPLGAESSITPLHPGDPTEASTNKESRKSLASFPTYVEVPGPCDPEDLIDGIIFAANYLGSTQLLSDKTPSKNVRMMQAQEAVSRIKTAQKLAKSRKKAPEGESQPMTEVDLFISTQRIKVLNADTQEPMMDHPLRTISYIADIGNIVVLMARRRMPRSNSQENVEASHPSQDAKRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDLLNTQDMYNDDLIHFSKSENCKDVFIEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKLNIVRCPPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPHEKIVHILSNAVGEIHMKTMPAAMYRLLTAQEQPVYI

Target ORF information:

RefSeq Version	NM_031779.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus amyloid beta precursor protein binding family A member 1 (Apba1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031779.2

ORF Insert Sequence:

ATGAACCACT TGGAGGGCTC CGCGGAGGTG GAGGTGGCCG ACGAGGCGCC AGGAGGGGAG 
GTGAACGAGT CCGTGGAGGC CGACCTGGAG CACCCCGAGG TGGAGGAAGA GCAGCAGCCG 
TCGCCCCCGC CGCCCGCAGG TCACGCACCC GAGGACCACC GCGCGCATCC GGCGCCGCCG 
CCGCCGCCAC CACCGCAGGA GGAGGAGGAG GAGCGCGGCG AGTGCCTGGC TCGCTCGGCC 
AGCACCGAGA GCGGCTTCCA CAACCACACG GACACCGCTG AGGGCGACGT GCTCGCCGCG 
GCCCGAGACG GCTACGAGGC GGAGCGCGCG CAGGACGCCG ACGATGAGAG CGCCTACGCC 
GTGCAGTACC GGCCCGAGGC CGAGGAGTAC ACGGAGCAGG CGGAGGCCGA GCACGCCGAG 
GCGGCGCAGC GGCGCGCGCT GCCCAACCAC CTGCACTTCC ACTCGCTGGA GCACGAGGAA 
GCCATGAACG CCGCCTACTC GGGCTATGTC TACACGCACC GGCTCTTCCA CCGCGCCGAG 
GACGAGCCCT ACGCCGAGCC CTACGCCGAC TACGGCGGCC TCCAGGAGCA CGTGTACGAG 
GAGATCGGGG ACGCGCCTGA GCTGGAGGCG CGCGACGGCC TGCGGCTCTA TGAGCGGGAG 
CGCGACGAGG CGGCCGCCTA CCGCCAGGAG GCCCTAGGCG CGCGGCTGCA CCACTACGAC 
GAGCGCTCCG ACGGCGAGTC CGACAGCCCC GAGAAGGAGG CGGAGTTCGC GCCCTACCCG 
CGCATGGACA GTTATGAGCA GGAAGAGGAC ATCGACCAGA TCGTGGCCGA GGTCAAGCAG 
AGCATGAGCT CGCAGAGCCT CGACAAGGCG GCCGAAGACA TGCCCGAGGC GGAGCAGGAC 
CTGGAGCGCG CCCCGACCCC GGGAGGGGGA CACCCCGACA GCCCTGGGCT GCCAGCACCT 
GCCGGGCAGC AGCAGCGAGT TGTGGGAACC CCGGGAGGCA GCGAGGTTGG TCAGCGGTAC 
AGCAAGGAAA AGAGGGATGC CATCTCGCTG GCCATCAAGG ACATCAAGGA GGCCATCGAA 
GAAGTGAAAA CCAGGACCAT CCGTTCGCCT TACACCCCCG ACGAACCCAA AGAGCCCATC 
TGGGTCATGC GCCAGGACAT TAGCCCCACA AGGGACTGTG ACGACCAGAG GCCCGTGGAC 
GGAGATTCTC CGTCTCCTGG CAGTTCCTCA CCCCTGGGTG CTGAGTCATC AATCACACCC 
CTTCATCCCG GTGACCCCAC GGAAGCCTCC ACTAATAAAG AGTCAAGAAA AAGCTTGGCT 
TCATTCCCAA CCTACGTTGA AGTTCCTGGA CCCTGCGACC CTGAAGACTT GATCGATGGA 
ATTATTTTTG CTGCCAATTA CCTTGGTTCC ACTCAGCTAC TCTCAGACAA AACTCCCTCC 
AAAAACGTGC GCATGATGCA GGCCCAGGAA GCAGTAAGCC GGATCAAGAC GGCCCAGAAA 
TTAGCCAAAA GCAGGAAGAA GGCTCCTGAA GGCGAATCTC AGCCAATGAC TGAGGTGGAC 
CTCTTCATCT CCACCCAGAG GATCAAAGTG TTGAATGCAG ATACACAGGA GCCTATGATG 
GACCACCCTC TGAGGACCAT TTCCTACATC GCAGACATTG GGAACATCGT CGTGCTGATG 
GCCCGCAGGC GGATGCCCCG CTCCAACTCC CAGGAGAATG TGGAGGCCTC TCACCCATCC 
CAGGATGCAA AACGGCAGTA CAAGATGATC TGTCATGTCT TTGAGTCTGA GGACGCCCAG 
CTGATCGCAC AGTCCATCGG GCAGGCCTTC AGCGTTGCAT ACCAGGAGTT CCTCAGGGCC 
AACGGGATTA ACCCAGAAGA CCTGAGCCAG AAGGAGTACA GCGACCTGCT CAACACCCAG 
GACATGTACA ACGATGACCT GATCCACTTC TCCAAGTCGG AAAACTGCAA AGATGTCTTC 
ATAGAGAAGC AGAAAGGAGA AATCCTGGGA GTTGTGATTG TGGAGTCTGG CTGGGGATCC 
ATTCTGCCAA CCGTGATCAT TGCCAACATG ATGCACGGAG GCCCCGCCGA GAAGTCGGGG 
AAGCTGAACA TCGGGGACCA GATCATGTCC ATTAACGGCA CCAGCCTGGT GGGCCTGCCC 
CTGTCCACCT GCCAGAGCAT CATTAAGGGC TTAAAGAACC AGTCCCGCGT GAAGCTGAAC 
ATCGTGAGGT GCCCCCCAGT GACCACAGTG CTAATTAGGA GGCCGGACCT TCGCTACCAG 
CTGGGTTTCA GCGTGCAGAA TGGAATTATC TGTAGCCTCA TGAGAGGGGG AATAGCTGAG 
AGAGGAGGTG TCCGCGTGGG ACATCGGATC ATTGAAATCA ACGGCCAGAG TGTCGTAGCC 
ACACCACACG AGAAGATCGT CCACATACTC TCCAATGCTG TTGGGGAGAT CCACATGAAG 
ACAATGCCAG CAGCCATGTA CAGACTGCTG ACAGCCCAGG AGCAGCCCGT TTACATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Scaffold protein X11α interacts with kalirin-7 in dendrites and recruits it to Golgi outposts.
The Journal of biological chemistry289(51)35517-29(2014 Dec)
Jones KA,Eng AG,Raval P,Srivastava DP,Penzes P

The INAD scaffold is a dynamic, redox-regulated modulator of signaling in the Drosophila eye.
Cell145(7)1088-101(2011 Jun)
Liu W,Wen W,Wei Z,Yu J,Ye F,Liu CH,Hardie RC,Zhang M

Cdk5 promotes synaptogenesis by regulating the subcellular distribution of the MAGUK family member CASK.
Neuron56(5)823-37(2007 Dec)
Samuels BA,Hsueh YP,Shu T,Liang H,Tseng HC,Hong CJ,Su SC,Volker J,Neve RL,Yue DT,Tsai LH

Reduction of mint-1, mint-2, and APP overexpression in okadaic acid-treated neurons.
Neuroreport18(18)1879-83(2007 Dec)
Yoon S,Choi J,Haam J,Choe H,Kim D

Genetic analysis of Mint/X11 proteins: essential presynaptic functions of a neuronal adaptor protein family.
The Journal of neuroscience : the official journal of the Society for Neuroscience26(50)13089-101(2006 Dec)
Ho A,Morishita W,Atasoy D,Liu X,Tabuchi K,Hammer RE,Malenka RC,Südhof TC

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Apba1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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