| Gene Symbol | Vdac1 |
| Entrez Gene ID | 83529 |
| Full Name | voltage-dependent anion channel 1 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | large diameter (2.5-3 nm) channel, permeable to ions and small molecules; molecular component of Ca2+ transport across the mitochondrial membranes [RGD, Jun 2006]. |
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Vdac1 cDNA ORF clone, Rattus norvegicus(Norway rat)
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Gene
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Clones
gRNAs
The following Vdac1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Vdac1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID ORa12452 Clone ID Related Accession (Same CDS sequence) NM_031353.1 Accession Version NM_031353.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 852bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1566230400000 Organism Rattus norvegicus(Norway rat) Product voltage-dependent anion-selective channel protein 1 Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB039662.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB039662.1, BC060558.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841ATGGCTGTGC CTCCCACATA TGCTGATCTT GGCAAGTCCG CCAGGGATGT CTTCACCAAG
GGCTACGGCT TTGGCTTAAT AAAACTTGAT TTGAAAACGA AGTCCGAGAA TGGATTGGAA
TTTACTAGCT CAGGTTCTGC CAACACGGAG ACCACCAAAG TGAACGGCAG TCTGGAAACC
AAGTACAGAT GGACCGAGTA TGGGCTGACG TTTACTGAGA AGTGGAACAC AGACAACACC
CTGGGCACTG AGATCACCGT GGAAGACCAG CTTGCTCGTG GACTGAAGCT GACCTTTGAT
TCATCTTTCT CGCCTAACAC TGGGAAAAAA AATGCTAAAA TCAAGACAGG GTACAAGAGG
GAGCATATCA ACCTGGGCTG TGATGTGGAC TTTGACATCG CTGGGCCCTC AATCCGGGGC
GCTCTGGTGC TTGGCTATGA GGGTTGGCTG GCTGGCTACC AGATGAATTT TGAGACCTCG
AAGTCCCGAG TGACCCAGAG CAACTTTGCA GTTGGCTACA AGACGGACGA ATTCCAGCTT
CATACTAATG TGAATGATGG GACGGAGTTT GGTGGCTCCA TTTACCAGAA GGTGAACAAG
AAGTTGGAGA CTGCTGTCAA TCTCGCCTGG ACCGCAGGAA ACAGTAACAC TCGCTTTGGA
ATAGCAGCCA AGTATCAGGT CGACCCTGAT GCCTGCTTTT CGGCCAAAGT GAACAACTCC
AGTCTAATTG GCTTAGGGTA CACTCAGACC CTAAAACCAG GTATCAAACT GACACTGTCA
GCCCTGCTGG ATGGCAAGAA CGTCAATGCG GGTGGCCACA AGCTTGGTTT AGGACTGGAA
TTTCAAGCAT AAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_112643.1 CDS 67..918 Translation 
Target ORF information:
RefSeq Version NM_031353.1 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus voltage-dependent anion channel 1 (Vdac1), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_031353.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841ATGGCTGTGC CTCCCACATA TGCTGATCTT GGCAAGTCCG CCAGGGATGT CTTCACCAAG
GGCTACGGCT TTGGCTTAAT AAAACTTGAT TTGAAAACGA AGTCCGAGAA TGGATTGGAA
TTTACTAGCT CAGGTTCTGC CAACACGGAG ACCACCAAAG TGAACGGCAG TCTGGAAACC
AAGTACAGAT GGACCGAGTA TGGGCTGACG TTTACTGAGA AGTGGAACAC AGACAACACC
CTGGGCACTG AGATCACCGT GGAAGACCAG CTTGCTCGTG GACTGAAGCT GACCTTTGAT
TCATCTTTCT CGCCTAACAC TGGGAAAAAA AATGCTAAAA TCAAGACAGG GTACAAGAGG
GAGCATATCA ACCTGGGCTG TGATGTGGAC TTTGACATCG CTGGGCCCTC AATCCGGGGC
GCTCTGGTGC TTGGCTATGA GGGTTGGCTG GCTGGCTACC AGATGAATTT TGAGACCTCG
AAGTCCCGAG TGACCCAGAG CAACTTTGCA GTTGGCTACA AGACGGACGA ATTCCAGCTT
CATACTAATG TGAATGATGG GACGGAGTTT GGTGGCTCCA TTTACCAGAA GGTGAACAAG
AAGTTGGAGA CTGCTGTCAA TCTCGCCTGG ACCGCAGGAA ACAGTAACAC TCGCTTTGGA
ATAGCAGCCA AGTATCAGGT CGACCCTGAT GCCTGCTTTT CGGCCAAAGT GAACAACTCC
AGTCTAATTG GCTTAGGGTA CACTCAGACC CTAAAACCAG GTATCAAACT GACACTGTCA
GCCCTGCTGG ATGGCAAGAA CGTCAATGCG GGTGGCCACA AGCTTGGTTT AGGACTGGAA
TTTCAAGCAT AAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Peroxynitrite nitrates adenine nucleotide translocase and voltage-dependent anion channel 1 and alters their interactions and association with hexokinase II in mitochondria.
Mitochondrion46380-392(2019 05)
Yang M,Xu Y,Heisner JS,Sun J,Stowe DF,Kwok WM,Camara AKS
WDR26/MIP2 interacts with VDAC1 and regulates VDAC1 expression levels in H9c2 cells.
Free radical biology & medicine11758-65(2018 03)
Jiang L,Wang H,Chen G,Feng Y,Zou J,Liu M,Liu K,Wang N,Zhang H,Wang K,Xiao X
Gene polymorphisms in the PI3K/AKT/mTOR signaling pathway contribute to prostate cancer susceptibility in Chinese men.
Oncotarget8(37)61305-61317(2017 Sep)
Liu T,Gulinaer A,Shi X,Wang F,An H,Cui W,Li Q
Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction.
The Journal of biological chemistry291(48)24986-25003(2016 Nov)
Ben-Hail D,Begas-Shvartz R,Shalev M,Shteinfer-Kuzmine A,Gruzman A,Reina S,De Pinto V,Shoshan-Barmatz V
lncRNA H19/miR-675 axis regulates cardiomyocyte apoptosis by targeting VDAC1 in diabetic cardiomyopathy.
Scientific reports636340(2016 10)
Li X,Wang H,Yao B,Xu W,Chen J,Zhou X
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