Thra cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Thra
Entrez Gene ID	81812
Full Name	thyroid hormone receptor alpha
Synonyms	ERBA1,Thra1,c-erbA-1
General protein information	Preferred Names thyroid hormone receptor alpha Names thyroid hormone receptor alpha c-erbAalpha2 C-erbA-alpha avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 1 c-erb-A thyroid hormone receptor c-erbA-alpha2 nuclear receptor subfamily 1 group A member 1 thyroid hormone receptor alpha 1 (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 1 formerly ERBA1)
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q31
Summary	binds the promoter of the Na+/H+ exchanger NHE1 and mediates thyroid hormone induced transcriptional activation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031134.2	NP_112396.2	c-erbAalpha2 isoform TRalpha2
NM_001017960.1	NP_001017960.1	thyroid hormone receptor alpha isoform TRalpha1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	THRA	XP_548137.2
Bos taurus (cattle)	THRA	NP_001039794.1
Xenopus tropicalis (tropical clawed frog)	thra	NP_001039261.1
Mus musculus (house mouse)	Thra	NP_835161.1
Homo sapiens (human)	THRA	NP_955366.1
Danio rerio (zebrafish)	thrab	XP_001921013.4
Rattus norvegicus (Norway rat)	Thra	NP_001017960.1
Gallus gallus (chicken)	THRA	NP_990644.1
Danio rerio (zebrafish)	thraa	NP_571471.1

Gene Ontology
Bibliography

Related articles in PubMed

Antidepressant behavior in thyroidectomized Wistar rats is induced by hippocampal hypothyroidism.
da Conceição RR, Laureano-Melo R, Oliveira KC, de Carvalho Melo MC, Kasamatsu TS, de Barros Maciel RM, de Souza JS, Giannocco G
Physiology & behavior157158-64(2016 Apr)

Nitric oxide and thyroid hormone receptor alpha 1 contribute to ovarian follicular development in immature hyper- and hypo-thyroid rats.
Zheng K, Sulieman FJ, Li J, Wei Q, Xu M, Shi F
Reproductive biology15(1)27-33(2015 Mar)

Local hypothyroidism favors the progression of preneoplastic lesions to hepatocellular carcinoma in rats.
Frau C, Loi R, Petrelli A, Perra A, Menegon S, Kowalik MA, Pinna S, Leoni VP, Fornari F, Gramantieri L, Ledda-Columbano GM, Giordano S, Columbano A
Hepatology (Baltimore, Md.)61(1)249-59(2015 Jan)

Action of specific thyroid hormone receptor α(1) and β(1) antagonists in the central and peripheral regulation of thyroid hormone metabolism in the rat.
van Beeren HC, Kwakkel J, Ackermans MT, Wiersinga WM, Fliers E, Boelen A
Thyroid : official journal of the American Thyroid Association22(12)1275-82(2012 Dec)

Thyroid hormone receptor isoform-specific modification by small ubiquitin-like modifier (SUMO) modulates thyroid hormone-dependent gene regulation.
Liu YY, Kogai T, Schultz JJ, Mody K, Brent GA
The Journal of biological chemistry287(43)36499-508(2012 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Thra gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Thra cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06047	NM_001017960.1 Latest version!	Rattus norvegicus thyroid hormone receptor alpha (Thra), transcript variant TRalpha1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa07699	NM_031134.2 Latest version!	Rattus norvegicus thyroid hormone receptor alpha (Thra), transcript variant TRalpha2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Thra ( NM_001017960.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001017960.1 Rattus norvegicus thyroid hormone receptor alpha (Thra), transcript variant TRalpha1, mRNA.

Price & Availability↑

CloneID	ORa06047
Clone ID Related Accession (Same CDS sequence)	NM_001017960.1
Accession Version	NM_001017960.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1233bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569168000000
Organism	Rattus norvegicus(Norway rat)
Product	thyroid hormone receptor alpha isoform TRalpha1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CO397265.1, M18028.1, CB728734.1 and X12744.1. Transcript Variant: This variant (TRalpha1) differs in the 3' UTR and coding region compared to TRalpha2, resulting in a shorter isoform (TRalpha1) with a distinct C-terminus. The TRalpha1 isoform, also known as c-erbAalpha1, functions as a thyroid hormone-dependent transcription factor. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M18028.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGAACAGA AGCCAAGCAA GGTGGAGTGT GGGTCAGACC CAGAGGAGAA CAGTGCCAGG 
TCACCAGATG GAAAGCGAAA AAGGAAGAAC GGCCAATGTC CCCTGAAAAG CAGCATGTCA 
GGGTATATCC CTAGTTACCT GGACAAAGAC GAGCAGTGTG TCGTGTGTGG GGACAAGGCC 
ACCGGTTATC ACTACCGCTG TATCACTTGT GAGGGCTGCA AGGGCTTCTT TCGCCGTACA 
ATCCAGAAGA ACCTCCATCC CACCTATTCC TGCAAATATG ACAGCTGCTG CGTCATCGAC 
AAGATCACCC GGAATCAGTG CCAGTTGTGC CGCTTCAAGA AGTGCATCGC TGTGGGCATG 
GCCATGGACC TGGTTCTAGA CGATTCAAAG CGGGTGGCCA AACGCAAGCT GATTGAGCAG 
AACCGGGAGA GGAGGCGAAA GGAGGAGATG ATCCGCTCGC TGCAGCAACG ACCAGAGCCC 
ACTCCTGAAG AGTGGGATCT GATCCACGTT GCTACAGAGG CCCATCGCAG CACCAATGCC 
CAGGGCAGCC ATTGGAAACA GAGGCGAAAA TTCCTGCCGG ATGACATTGG CCAGTCACCT 
ATTGTCTCCA TGCCGGACGG AGACAAGGTA GACCTAGAGG CCTTCAGCGA GTTTACCAAG 
ATCATCACCC CGGCCATCAC CCGCGTGGTG GACTTTGCCA AAAAACTGCC CATGTTCTCC 
GAGCTGCCTT GTGAAGACCA GATCATCCTC CTGAAGGGCT GCTGCATGGA GATCATGTCC 
CTGCGGGCAG CTGTCCGCTA TGACCCTGAG AGCGACACCC TGACCCTGAG TGGGGAGATG 
GCGGTTAAGC GGGAGCAGCT CAAGAATGGT GGCTTGGGTG TAGTCTCCGA CGCCATCTTT 
GAACTGGGCA AGTCACTCTC TGCCTTTAAC CTGGATGATA CGGAAGTGGC TCTGCTGCAG 
GCTGTGCTGT TAATGTCAAC AGACCGCTCT GGCCTGCTGT GTGTGGACAA GATCGAGAAG 
AGTCAGGAGG CCTACCTGCT GGCGTTTGAG CACTACGTCA ACCACCGCAA ACACAACATT 
CCGCACTTCT GGCCCAAGCT GCTGATGAAG GTGACTGACC TCCGCATGAT CGGGGCCTGC 
CACGCCAGCC GCTTCCTCCA CATGAAAGTC GAGTGCCCCA CCGAACTCTT CCCCCCACTC 
TTCCTGGAGG TCTTTGAGGA TCAGGAAGTC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001017960.1
CDS	435..1667
Translation	MEQKPSKVECGSDPEENSARSPDGKRKRKNGQCPLKSSMSGYIPSYLDKDEQCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHVATEAHRSTNAQGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNIPHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFEDQEV

Target ORF information:

RefSeq Version	NM_001017960.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus thyroid hormone receptor alpha (Thra), transcript variant TRalpha1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001017960.1

ORF Insert Sequence:

ATGGAACAGA AGCCAAGCAA GGTGGAGTGT GGGTCAGACC CAGAGGAGAA CAGTGCCAGG 
TCACCAGATG GAAAGCGAAA AAGGAAGAAC GGCCAATGTC CCCTGAAAAG CAGCATGTCA 
GGGTATATCC CTAGTTACCT GGACAAAGAC GAGCAGTGTG TCGTGTGTGG GGACAAGGCC 
ACCGGTTATC ACTACCGCTG TATCACTTGT GAGGGCTGCA AGGGCTTCTT TCGCCGTACA 
ATCCAGAAGA ACCTCCATCC CACCTATTCC TGCAAATATG ACAGCTGCTG CGTCATCGAC 
AAGATCACCC GGAATCAGTG CCAGTTGTGC CGCTTCAAGA AGTGCATCGC TGTGGGCATG 
GCCATGGACC TGGTTCTAGA CGATTCAAAG CGGGTGGCCA AACGCAAGCT GATTGAGCAG 
AACCGGGAGA GGAGGCGAAA GGAGGAGATG ATCCGCTCGC TGCAGCAACG ACCAGAGCCC 
ACTCCTGAAG AGTGGGATCT GATCCACGTT GCTACAGAGG CCCATCGCAG CACCAATGCC 
CAGGGCAGCC ATTGGAAACA GAGGCGAAAA TTCCTGCCGG ATGACATTGG CCAGTCACCT 
ATTGTCTCCA TGCCGGACGG AGACAAGGTA GACCTAGAGG CCTTCAGCGA GTTTACCAAG 
ATCATCACCC CGGCCATCAC CCGCGTGGTG GACTTTGCCA AAAAACTGCC CATGTTCTCC 
GAGCTGCCTT GTGAAGACCA GATCATCCTC CTGAAGGGCT GCTGCATGGA GATCATGTCC 
CTGCGGGCAG CTGTCCGCTA TGACCCTGAG AGCGACACCC TGACCCTGAG TGGGGAGATG 
GCGGTTAAGC GGGAGCAGCT CAAGAATGGT GGCTTGGGTG TAGTCTCCGA CGCCATCTTT 
GAACTGGGCA AGTCACTCTC TGCCTTTAAC CTGGATGATA CGGAAGTGGC TCTGCTGCAG 
GCTGTGCTGT TAATGTCAAC AGACCGCTCT GGCCTGCTGT GTGTGGACAA GATCGAGAAG 
AGTCAGGAGG CCTACCTGCT GGCGTTTGAG CACTACGTCA ACCACCGCAA ACACAACATT 
CCGCACTTCT GGCCCAAGCT GCTGATGAAG GTGACTGACC TCCGCATGAT CGGGGCCTGC 
CACGCCAGCC GCTTCCTCCA CATGAAAGTC GAGTGCCCCA CCGAACTCTT CCCCCCACTC 
TTCCTGGAGG TCTTTGAGGA TCAGGAAGTC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Thra ( NM_031134.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_112396.2 Rattus norvegicus thyroid hormone receptor alpha (Thra), transcript variant TRalpha2, mRNA.

Price & Availability↑

CloneID	ORa07699
Clone ID Related Accession (Same CDS sequence)	NM_031134.2
Accession Version	NM_031134.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569168000000
Organism	Rattus norvegicus(Norway rat)
Product	c-erbAalpha2 isoform TRalpha2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from M31174.1, CB580585.1 and AI764185.1. On May 6, 2005 this sequence version replaced NM_031134.1. Transcript Variant: This variant (TRalpha2) contains an alternate 3' terminal exon compared to variant TRalpha1. The resulting protein (c-erbAalpha2, also known as TRalpha 2) has a distinct C-terminus compared to isoform TRalpha1, and fails to bind thyroid hormones or to trans-activate thyroid hormone responsive genes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: M31174.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAACAGA AGCCAAGCAA GGTGGAGTGT GGGTCAGACC CAGAGGAGAA CAGTGCCAGG 
TCACCAGATG GAAAGCGAAA AAGGAAGAAC GGCCAATGTC CCCTGAAAAG CAGCATGTCA 
GGGTATATCC CTAGTTACCT GGACAAAGAC GAGCAGTGTG TCGTGTGTGG GGACAAGGCC 
ACCGGTTATC ACTACCGCTG TATCACTTGT GAGGGCTGCA AGGGCTTCTT TCGCCGTACA 
ATCCAGAAGA ACCTCCATCC CACCTATTCC TGCAAATATG ACAGCTGCTG CGTCATCGAC 
AAGATCACCC GGAATCAGTG CCAGTTGTGC CGCTTCAAGA AGTGCATCGC TGTGGGCATG 
GCCATGGACC TGGTTCTAGA CGATTCAAAG CGGGTGGCCA AACGCAAGCT GATTGAGCAG 
AACCGGGAGA GGAGGCGAAA GGAGGAGATG ATCCGCTCGC TGCAGCAACG ACCAGAGCCC 
ACTCCTGAAG AGTGGGATCT GATCCACGTT GCTACAGAGG CCCATCGCAG CACCAATGCC 
CAGGGCAGCC ATTGGAAACA GAGGCGAAAA TTCCTGCCGG ATGACATTGG CCAGTCACCT 
ATTGTCTCCA TGCCGGACGG AGACAAGGTA GACCTAGAGG CCTTCAGCGA GTTTACCAAG 
ATCATCACCC CGGCCATCAC CCGCGTGGTG GACTTTGCCA AAAAACTGCC CATGTTCTCC 
GAGCTGCCTT GTGAAGACCA GATCATCCTC CTGAAGGGCT GCTGCATGGA GATCATGTCC 
CTGCGGGCAG CTGTCCGCTA TGACCCTGAG AGCGACACCC TGACCCTGAG TGGGGAGATG 
GCGGTTAAGC GGGAGCAGCT CAAGAATGGT GGCTTGGGTG TAGTCTCCGA CGCCATCTTT 
GAACTGGGCA AGTCACTCTC TGCCTTTAAC CTGGATGATA CGGAAGTGGC TCTGCTGCAG 
GCTGTGCTGT TAATGTCAAC AGACCGCTCT GGCCTGCTGT GTGTGGACAA GATCGAGAAG 
AGTCAGGAGG CCTACCTGCT GGCGTTTGAG CACTACGTCA ACCACCGCAA ACACAACATT 
CCGCACTTCT GGCCCAAGCT GCTGATGAAG GAGAGAGAAG TGCAGAGTTC GATTCTGTAC 
AAGGGGGCAG CGGCAGAAGG CCGGCCGGGC GGGTCACTGG GCGTCCACCC GGAAGGACAG 
CAGCTTCTCG GAATGCATGT TGTTCAGGGT CCGCAGGTCC GGCAGCTTGA GCAGCAGTTT 
GGTGAAGCGG GAAGTCTCCG AGGGCCGGTT CTTCAGCACC AGAGCCCGAA GAGCCCGCAG 
CAGCGTCTCC TGGAGCTGCT CCACCGAAGC GGAATTCTCC ATTCCCGAGC GGTCTGTGGG 
GAAGACGACA GCAGTGAGGC AAGCTCCCTG AGCTCCTCTT CCTCTGACGA GGACACGGAG 
GTCTGCGAGG ACCTGGCAGG CAAGGCAGCC TCTCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112396.2
CDS	303..1781
Translation	MEQKPSKVECGSDPEENSARSPDGKRKRKNGQCPLKSSMSGYIPSYLDKDEQCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHVATEAHRSTNAQGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNIPHFWPKLLMKEREVQSSILYKGAAAEGRPGGSLGVHPEGQQLLGMHVVQGPQVRQLEQQFGEAGSLRGPVLQHQSPKSPQQRLLELLHRSGILHSRAVCGEDDSSEASSLSSSSSDEDTEVCEDLAGKAASP

Target ORF information:

RefSeq Version	NM_031134.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus thyroid hormone receptor alpha (Thra), transcript variant TRalpha2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031134.2

ORF Insert Sequence:

ATGGAACAGA AGCCAAGCAA GGTGGAGTGT GGGTCAGACC CAGAGGAGAA CAGTGCCAGG 
TCACCAGATG GAAAGCGAAA AAGGAAGAAC GGCCAATGTC CCCTGAAAAG CAGCATGTCA 
GGGTATATCC CTAGTTACCT GGACAAAGAC GAGCAGTGTG TCGTGTGTGG GGACAAGGCC 
ACCGGTTATC ACTACCGCTG TATCACTTGT GAGGGCTGCA AGGGCTTCTT TCGCCGTACA 
ATCCAGAAGA ACCTCCATCC CACCTATTCC TGCAAATATG ACAGCTGCTG CGTCATCGAC 
AAGATCACCC GGAATCAGTG CCAGTTGTGC CGCTTCAAGA AGTGCATCGC TGTGGGCATG 
GCCATGGACC TGGTTCTAGA CGATTCAAAG CGGGTGGCCA AACGCAAGCT GATTGAGCAG 
AACCGGGAGA GGAGGCGAAA GGAGGAGATG ATCCGCTCGC TGCAGCAACG ACCAGAGCCC 
ACTCCTGAAG AGTGGGATCT GATCCACGTT GCTACAGAGG CCCATCGCAG CACCAATGCC 
CAGGGCAGCC ATTGGAAACA GAGGCGAAAA TTCCTGCCGG ATGACATTGG CCAGTCACCT 
ATTGTCTCCA TGCCGGACGG AGACAAGGTA GACCTAGAGG CCTTCAGCGA GTTTACCAAG 
ATCATCACCC CGGCCATCAC CCGCGTGGTG GACTTTGCCA AAAAACTGCC CATGTTCTCC 
GAGCTGCCTT GTGAAGACCA GATCATCCTC CTGAAGGGCT GCTGCATGGA GATCATGTCC 
CTGCGGGCAG CTGTCCGCTA TGACCCTGAG AGCGACACCC TGACCCTGAG TGGGGAGATG 
GCGGTTAAGC GGGAGCAGCT CAAGAATGGT GGCTTGGGTG TAGTCTCCGA CGCCATCTTT 
GAACTGGGCA AGTCACTCTC TGCCTTTAAC CTGGATGATA CGGAAGTGGC TCTGCTGCAG 
GCTGTGCTGT TAATGTCAAC AGACCGCTCT GGCCTGCTGT GTGTGGACAA GATCGAGAAG 
AGTCAGGAGG CCTACCTGCT GGCGTTTGAG CACTACGTCA ACCACCGCAA ACACAACATT 
CCGCACTTCT GGCCCAAGCT GCTGATGAAG GAGAGAGAAG TGCAGAGTTC GATTCTGTAC 
AAGGGGGCAG CGGCAGAAGG CCGGCCGGGC GGGTCACTGG GCGTCCACCC GGAAGGACAG 
CAGCTTCTCG GAATGCATGT TGTTCAGGGT CCGCAGGTCC GGCAGCTTGA GCAGCAGTTT 
GGTGAAGCGG GAAGTCTCCG AGGGCCGGTT CTTCAGCACC AGAGCCCGAA GAGCCCGCAG 
CAGCGTCTCC TGGAGCTGCT CCACCGAAGC GGAATTCTCC ATTCCCGAGC GGTCTGTGGG 
GAAGACGACA GCAGTGAGGC AAGCTCCCTG AGCTCCTCTT CCTCTGACGA GGACACGGAG 
GTCTGCGAGG ACCTGGCAGG CAAGGCAGCC TCTCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Antidepressant behavior in thyroidectomized Wistar rats is induced by hippocampal hypothyroidism.
Physiology & behavior157158-64(2016 Apr)
da Conceição RR,Laureano-Melo R,Oliveira KC,de Carvalho Melo MC,Kasamatsu TS,de Barros Maciel RM,de Souza JS,Giannocco G

Nitric oxide and thyroid hormone receptor alpha 1 contribute to ovarian follicular development in immature hyper- and hypo-thyroid rats.
Reproductive biology15(1)27-33(2015 Mar)
Zheng K,Sulieman FJ,Li J,Wei Q,Xu M,Shi F

Local hypothyroidism favors the progression of preneoplastic lesions to hepatocellular carcinoma in rats.
Hepatology (Baltimore, Md.)61(1)249-59(2015 Jan)
Frau C,Loi R,Petrelli A,Perra A,Menegon S,Kowalik MA,Pinna S,Leoni VP,Fornari F,Gramantieri L,Ledda-Columbano GM,Giordano S,Columbano A

Action of specific thyroid hormone receptor α(1) and β(1) antagonists in the central and peripheral regulation of thyroid hormone metabolism in the rat.
Thyroid : official journal of the American Thyroid Association22(12)1275-82(2012 Dec)
van Beeren HC,Kwakkel J,Ackermans MT,Wiersinga WM,Fliers E,Boelen A

Thyroid hormone receptor isoform-specific modification by small ubiquitin-like modifier (SUMO) modulates thyroid hormone-dependent gene regulation.
The Journal of biological chemistry287(43)36499-508(2012 Oct)
Liu YY,Kogai T,Schultz JJ,Mody K,Brent GA

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Thra cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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