Mapk14 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mapk14
Entrez Gene ID	81649
Full Name	mitogen activated protein kinase 14
Synonyms	CRK1,CSBP,CSPB1,Csbp1,Csbp2,Exip,Hog,Mxi2,Prkm14,Prkm15,RK,Sapk2A,p38,p38Hog,p38alpha
General protein information	Preferred Names mitogen activated protein kinase 14 Names mitogen-activated protein kinase 14 Csaids binding protein MAP kinase 14 MAP kinase 2 MAP kinase Mxi2 MAP kinase p38 alpha MAPK 14 MAX-interacting protein 2 cytokine suppressive anti-inflammatory drug binding protein cytokine-supressive anti-inflammatory drug binding protein mitogen-activated protein kinase 14A mitogen-activated protein kinase p38 alpha p38 MAP kinase p38 mitogen activated protein kinase p38alpha Exip reactive kinase stress-activated protein kinase 2A
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 20 Map Location: 20p12
Summary	mitogen-activated protein kinase; involved in intracellular signalling, inhibition of apoptosis and gene activation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017601781.1	XP_017457270.1	mitogen-activated protein kinase 14 isoform X2
XM_006256142.3	XP_006256204.1	mitogen-activated protein kinase 14 isoform X1
NM_031020.2	NP_112282.2	mitogen-activated protein kinase 14

Pathways from BioSystems

Homologies

Neurospora crassa	NCU07024	XP_962163.2
Homo sapiens (human)	MAPK14	NP_001306.1
Saccharomyces cerevisiae (baker's yeast)	HOG1	NP_013214.1
Kluyveromyces lactis	KLLA0F20053g	XP_455981.1
Eremothecium gossypii	AGOS_AGR048C	NP_986713.1
Canis lupus familiaris (dog)	MAPK14	NP_001003206.1
Rattus norvegicus (Norway rat)	Mapk14	NP_112282.2
Oryza sativa (rice)	Os03g0285800	NP_001049770.1
Magnaporthe oryzae (rice blast fungus)	MGG_01822	XP_003714838.1
Bos taurus (cattle)	MAPK14	NP_001095644.1
Drosophila melanogaster (fruit fly)	Mpk2	NP_001163711.1
Caenorhabditis elegans (roundworm)	pmk-1	NP_501365.1
Xenopus tropicalis (tropical clawed frog)	mapk14	NP_001005824.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012148	XP_320380.4
Schizosaccharomyces pombe (fission yeast)	sty1	NP_592843.1
Macaca mulatta (Rhesus monkey)	LOC718976	XP_001112423.2
Mus musculus (house mouse)	Mapk14	NP_001161980.1
Gallus gallus (chicken)	MAPK14	XP_001232616.1
Pan troglodytes (chimpanzee)	MAPK14	NP_001009065.1
Danio rerio (zebrafish)	mapk14a	NP_571797.1
Drosophila melanogaster (fruit fly)	p38b	NP_477361.1
Arabidopsis thaliana (thale cress)	MPK3	NP_190150.1

Gene Ontology
Bibliography

Related articles in PubMed

Potential contribution of microRNA-125b targeting p38MAPK to relieving intermittent hypoxia-induced dementia of rat models.
Ren H, Qiu W, Lu Q, Peng C, Ding Y, Zhu B, Li Q, Chen X
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia64234-241(2019 Jun)

Astragaloside IV ameliorates endoplasmic reticulum stress‑induced apoptosis of Aβ25‑35‑treated PC12 cells by inhibiting the p38 MAPK signaling pathway.
Ma Y, Xiong L
Molecular medicine reports19(3)2005-2012(2019 Mar)

p38-MAP Kinase Negatively Regulates the Slow Force Response to Stretch in Rat Myocardium through the Up-Regulation of Dual Specificity Phosphatase 6 (DUSP6).
Zavala MR, Díaz RG, Medina AJ, Acosta MP, Escudero DS, Ennis IL, Pérez NG, Villa-Abrille MC
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology52(2)172-185(2019)

Cigarette smoke extracts and cadmium induce COX-2 expression through γ-secretase-mediated p38 MAPK activation in C6 astroglia cells.
Lim HJ, Park JH, Jo C, Yoon K, Koh YH
PloS one14(2)e0212749(2019)

Reduced nicotinamide adenine dinucleotide phosphate inhibits rat platelet aggregation and p38 phosphorylation.
Gu Y, Sheng R, Wu J, Zhou Y, Qin ZH
Thrombosis research171121-129(2018 11)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Mapk14 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mapk14 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa13316	NM_031020.2 Latest version!	Rattus norvegicus mitogen activated protein kinase 14 (Mapk14), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa39275	XM_006256142.3 Latest version!	Rattus norvegicus mitogen activated protein kinase 14 (Mapk14), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa60193	XM_017601781.1 Latest version!	Rattus norvegicus mitogen activated protein kinase 14 (Mapk14), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mapk14 ( NM_031020.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_112282.2 Rattus norvegicus mitogen activated protein kinase 14 (Mapk14), mRNA.

Price & Availability↑

CloneID	ORa13316
Clone ID Related Accession (Same CDS sequence)	NM_031020.2
Accession Version	NM_031020.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1574611200000
Organism	Rattus norvegicus(Norway rat)
Product	mitogen-activated protein kinase 14
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC092193.1. On Apr 11, 2005 this sequence version replaced NM_031020.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC092193.1, AB000783.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTCGCAGG AGAGGCCCAC GTTCTACCGG CAGGAGCTGA ACAAGACCGT CTGGGAGGTG 
CCCGAGCGAT ACCAGAACCT GTCCCCGGTG GGCTCGGGAG CCTACGGCTC GGTGTGTGCT 
GCTTTTGATA CAAAGACGGG ACATCGTGTG GCAGTGAAGA AGCTGTCGAG ACCGTTTCAG 
TCCATCATTC ACGCCAAAAG GACCTACAGG GAGCTGCGGC TGCTGAAGCA CATGAAGCAC 
GAGAATGTGA TTGGTCTGTT GGATGTGTTT ACACCTGCAA GGTCCCTGGA GGAATTCAAC 
GATGTGTACC TGGTGACCCA TCTCATGGGG GCAGACCTGA ACAACATCGT GAAGTGTCAG 
AAGCTTACCG ATGACCACGT TCAGTTTCTT ATCTACCAGA TCCTGCGAGG GCTGAAGTAT 
ATACACTCGG CTGACATAAT CCACAGGGAC CTAAAGCCCA GCAACCTCGC TGTGAATGAA 
GACTGTGAGC TGAAGATTCT GGATTTTGGG CTGGCTCGGC ACACTGATGA CGAAATGACC 
GGCTACGTGG CTACCCGGTG GTACAGAGCC CCCGAGATTA TGCTGAATTG GATGCACTAC 
AACCAGACAG TGGATATTTG GTCCGTGGGC TGCATCATGG CTGAGCTGTT GACCGGAAGA 
ACGTTGTTTC CTGGTACAGA CCATATTAAC CAGCTTCAGC AGATAATGCG TCTGACGGGG 
ACACCCCCTG CTTATCTCAT TAACAGGATG CCAAGCCATG AGGCAAGAAA CTACATTCAG 
TCTCTGGCCC AGATGCCGAA GATGAACTTC GCAAATGTAT TTATTGGTGC CAATCCCCTG 
GCTGTCGACC TGCTGGAAAA GATGCTGGTT TTGGACTCGG ATAAGAGGAT CACAGCAGCC 
CAAGCTCTTG CGCATGCCTA CTTTGCTCAG TACCACGACC CTGATGATGA GCCAGTGGCT 
GACCCTTATG ACCAGTCCTT TGAAAGCAGG GACCTCCTTA TAGACGAATG GAAGAGCCTG 
ACCTACGATG AAGTCATTAG CTTTGTGCCA CCGCCCCTTG ACCAAGAAGA AATGGAGTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112282.2
CDS	304..1386
Translation	MSQERPTFYRQELNKTVWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPAYLINRMPSHEARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES

Target ORF information:

RefSeq Version	NM_031020.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus mitogen activated protein kinase 14 (Mapk14), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031020.2

ORF Insert Sequence:

ATGTCGCAGG AGAGGCCCAC GTTCTACCGG CAGGAGCTGA ACAAGACCGT CTGGGAGGTG 
CCCGAGCGAT ACCAGAACCT GTCCCCGGTG GGCTCGGGAG CCTACGGCTC GGTGTGTGCT 
GCTTTTGATA CAAAGACGGG ACATCGTGTG GCAGTGAAGA AGCTGTCGAG ACCGTTTCAG 
TCCATCATTC ACGCCAAAAG GACCTACAGG GAGCTGCGGC TGCTGAAGCA CATGAAGCAC 
GAGAATGTGA TTGGTCTGTT GGATGTGTTT ACACCTGCAA GGTCCCTGGA GGAATTCAAC 
GATGTGTACC TGGTGACCCA TCTCATGGGG GCAGACCTGA ACAACATCGT GAAGTGTCAG 
AAGCTTACCG ATGACCACGT TCAGTTTCTT ATCTACCAGA TCCTGCGAGG GCTGAAGTAT 
ATACACTCGG CTGACATAAT CCACAGGGAC CTAAAGCCCA GCAACCTCGC TGTGAATGAA 
GACTGTGAGC TGAAGATTCT GGATTTTGGG CTGGCTCGGC ACACTGATGA CGAAATGACC 
GGCTACGTGG CTACCCGGTG GTACAGAGCC CCCGAGATTA TGCTGAATTG GATGCACTAC 
AACCAGACAG TGGATATTTG GTCCGTGGGC TGCATCATGG CTGAGCTGTT GACCGGAAGA 
ACGTTGTTTC CTGGTACAGA CCATATTAAC CAGCTTCAGC AGATAATGCG TCTGACGGGG 
ACACCCCCTG CTTATCTCAT TAACAGGATG CCAAGCCATG AGGCAAGAAA CTACATTCAG 
TCTCTGGCCC AGATGCCGAA GATGAACTTC GCAAATGTAT TTATTGGTGC CAATCCCCTG 
GCTGTCGACC TGCTGGAAAA GATGCTGGTT TTGGACTCGG ATAAGAGGAT CACAGCAGCC 
CAAGCTCTTG CGCATGCCTA CTTTGCTCAG TACCACGACC CTGATGATGA GCCAGTGGCT 
GACCCTTATG ACCAGTCCTT TGAAAGCAGG GACCTCCTTA TAGACGAATG GAAGAGCCTG 
ACCTACGATG AAGTCATTAG CTTTGTGCCA CCGCCCCTTG ACCAAGAAGA AATGGAGTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mapk14 ( XM_006256142.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006256204.1 Rattus norvegicus mitogen activated protein kinase 14 (Mapk14), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa39275
Clone ID Related Accession (Same CDS sequence)	XM_006256142.3
Accession Version	XM_006256142.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	mitogen-activated protein kinase 14 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005119.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006256142.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGCAGG AGAGGCCCAC GTTCTACCGG CAGGAGCTGA ACAAGACCGT CTGGGAGGTG 
CCCGAGCGAT ACCAGAACCT GTCCCCGGTG GGCTCGGGAG CCTACGGCTC GGTGTGTGCT 
GCTTTTGATA CAAAGACGGG ACATCGTGTG GCAGTGAAGA AGCTGTCGAG ACCGTTTCAG 
TCCATCATTC ACGCCAAAAG GACCTACAGG GAGCTGCGGC TGCTGAAGCA CATGAAGCAC 
GAGAATGTGA TTGGTCTGTT GGATGTGTTT ACACCTGCAA GGTCCCTGGA GGAATTCAAC 
GATGTGTACC TGGTGACCCA TCTCATGGGG GCAGACCTGA ACAACATCGT GAAGTGTCAG 
AAGCTTACCG ATGACCACGT TCAGTTTCTT ATCTACCAGA TCCTGCGAGG GCTGAAGTAT 
ATACACTCGG CTGACATAAT CCACAGGGAC CTAAAGCCCA GCAACCTCGC TGTGAATGAA 
GACTGTGAGC TGAAGATTCT GGATTTTGGG CTGGCTCGGC ACACTGATGA CGAAATGACC 
GGCTACGTGG CTACCCGGTG GTACAGAGCC CCCGAGATTA TGCTGAATTG GATGCACTAC 
AACCAGACAG TGGATATTTG GTCCGTGGGC TGCATCATGG CTGAGCTGTT GACCGGAAGA 
ACGTTGTTTC CTGGTACAGA CCATATTGAT CAGTTGAAGC TCATTTTAAG ACTCGTTGGA 
ACCCCAGGGG CTGAGCTTCT GAAGAAAATC TCCTCAGAGT CTGCAAGAAA CTACATTCAG 
TCTCTGGCCC AGATGCCGAA GATGAACTTC GCAAATGTAT TTATTGGTGC CAATCCCCTG 
GCTGTCGACC TGCTGGAAAA GATGCTGGTT TTGGACTCGG ATAAGAGGAT CACAGCAGCC 
CAAGCTCTTG CGCATGCCTA CTTTGCTCAG TACCACGACC CTGATGATGA GCCAGTGGCT 
GACCCTTATG ACCAGTCCTT TGAAAGCAGG GACCTCCTTA TAGACGAATG GAAGAGCCTG 
ACCTACGATG AAGTCATTAG CTTTGTGCCA CCGCCCCTTG ACCAAGAAGA AATGGAGTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006256204.1
CDS	311..1393
Translation	MSQERPTFYRQELNKTVWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES

Target ORF information:

RefSeq Version	XM_006256142.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus mitogen activated protein kinase 14 (Mapk14), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006256142.3

ORF Insert Sequence:

ATGTCGCAGG AGAGGCCCAC GTTCTACCGG CAGGAGCTGA ACAAGACCGT CTGGGAGGTG 
CCCGAGCGAT ACCAGAACCT GTCCCCGGTG GGCTCGGGAG CCTACGGCTC GGTGTGTGCT 
GCTTTTGATA CAAAGACGGG ACATCGTGTG GCAGTGAAGA AGCTGTCGAG ACCGTTTCAG 
TCCATCATTC ACGCCAAAAG GACCTACAGG GAGCTGCGGC TGCTGAAGCA CATGAAGCAC 
GAGAATGTGA TTGGTCTGTT GGATGTGTTT ACACCTGCAA GGTCCCTGGA GGAATTCAAC 
GATGTGTACC TGGTGACCCA TCTCATGGGG GCAGACCTGA ACAACATCGT GAAGTGTCAG 
AAGCTTACCG ATGACCACGT TCAGTTTCTT ATCTACCAGA TCCTGCGAGG GCTGAAGTAT 
ATACACTCGG CTGACATAAT CCACAGGGAC CTAAAGCCCA GCAACCTCGC TGTGAATGAA 
GACTGTGAGC TGAAGATTCT GGATTTTGGG CTGGCTCGGC ACACTGATGA CGAAATGACC 
GGCTACGTGG CTACCCGGTG GTACAGAGCC CCCGAGATTA TGCTGAATTG GATGCACTAC 
AACCAGACAG TGGATATTTG GTCCGTGGGC TGCATCATGG CTGAGCTGTT GACCGGAAGA 
ACGTTGTTTC CTGGTACAGA CCATATTGAT CAGTTGAAGC TCATTTTAAG ACTCGTTGGA 
ACCCCAGGGG CTGAGCTTCT GAAGAAAATC TCCTCAGAGT CTGCAAGAAA CTACATTCAG 
TCTCTGGCCC AGATGCCGAA GATGAACTTC GCAAATGTAT TTATTGGTGC CAATCCCCTG 
GCTGTCGACC TGCTGGAAAA GATGCTGGTT TTGGACTCGG ATAAGAGGAT CACAGCAGCC 
CAAGCTCTTG CGCATGCCTA CTTTGCTCAG TACCACGACC CTGATGATGA GCCAGTGGCT 
GACCCTTATG ACCAGTCCTT TGAAAGCAGG GACCTCCTTA TAGACGAATG GAAGAGCCTG 
ACCTACGATG AAGTCATTAG CTTTGTGCCA CCGCCCCTTG ACCAAGAAGA AATGGAGTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mapk14 ( XM_017601781.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017457270.1 Rattus norvegicus mitogen activated protein kinase 14 (Mapk14), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa60193
Clone ID Related Accession (Same CDS sequence)	XM_017601781.1
Accession Version	XM_017601781.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 924bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	mitogen-activated protein kinase 14 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005119.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGCAGG AGAGGCCCAC GTTCTACCGG CAGGAGCTGA ACAAGACCGT CTGGGAGGTG 
CCCGAGCGAT ACCAGAACCT GTCCCCGGTG GGCTCGGGAG CCTACGGCTC GGTGTGTGCT 
GCTTTTGATA CAAAGACGGG ACATCGTGTG GCAGTGAAGA AGCTGTCGAG ACCGTTTCAG 
TCCATCATTC ACGCCAAAAG GACCTACAGG GAGCTGCGGC TGCTGAAGCA CATGAAGCAC 
GAGAATGTGA TTGGTCTGTT GGATGTGTTT ACACCTGCAA GGTCCCTGGA GGAATTCAAC 
GATGTGTACC TGGTGACCCA TCTCATGGGG GCAGACCTGA ACAACATCGT GAAGTGTCAG 
AAGCTTACCG ATGACCACGT TCAGTTTCTT ATCTACCAGA TCCTGCGAGG GCTGAAGTAT 
ATACACTCGG CTGACATAAT CCACAGGGAC CTAAAGCCCA GCAACCTCGC TGTGAATGAA 
GACTGTGAGC TGAAGATTCT GGATTTTGGG CTGGCTCGGC ACACTGATGA CGAAATGACC 
GGCTACGTGG CTACCCGGTG GTACAGAGCC CCCGAGATTA TGCTGAATTG GATGCACTAC 
AACCAGACAG TGGATATTTG GTCCGTGGGC TGCATCATGG CTGAGCTGTT GACCGGAAGA 
ACGTTGTTTC CTGGTACAGA CCATATTGAT CAGTTGAAGC TCATTTTAAG ACTCGTTGGA 
ACCCCAGGGG CTGAGCTTCT GAAGAAAATC TCCTCAGAGT CTCTGTCGAC CTGCTGGAAA 
AGATGCTGGT TTTGGACTCG GATAAGAGGA TCACAGCAGC CCAAGCTCTT GCGCATGCCT 
ACTTTGCTCA GTACCACGAC CCTGATGATG AGCCAGTGGC TGACCCTTAT GACCAGTCCT 
TTGAAAGCAG GGACCTCCTT ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017457270.1
CDS	317..1240
Translation	MSQERPTFYRQELNKTVWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESLSTCWKRCWFWTRIRGSQQPKLLRMPTLLSTTTLMMSQWLTLMTSPLKAGTSL

Target ORF information:

RefSeq Version	XM_017601781.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus mitogen activated protein kinase 14 (Mapk14), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017601781.1

ORF Insert Sequence:

ATGTCGCAGG AGAGGCCCAC GTTCTACCGG CAGGAGCTGA ACAAGACCGT CTGGGAGGTG 
CCCGAGCGAT ACCAGAACCT GTCCCCGGTG GGCTCGGGAG CCTACGGCTC GGTGTGTGCT 
GCTTTTGATA CAAAGACGGG ACATCGTGTG GCAGTGAAGA AGCTGTCGAG ACCGTTTCAG 
TCCATCATTC ACGCCAAAAG GACCTACAGG GAGCTGCGGC TGCTGAAGCA CATGAAGCAC 
GAGAATGTGA TTGGTCTGTT GGATGTGTTT ACACCTGCAA GGTCCCTGGA GGAATTCAAC 
GATGTGTACC TGGTGACCCA TCTCATGGGG GCAGACCTGA ACAACATCGT GAAGTGTCAG 
AAGCTTACCG ATGACCACGT TCAGTTTCTT ATCTACCAGA TCCTGCGAGG GCTGAAGTAT 
ATACACTCGG CTGACATAAT CCACAGGGAC CTAAAGCCCA GCAACCTCGC TGTGAATGAA 
GACTGTGAGC TGAAGATTCT GGATTTTGGG CTGGCTCGGC ACACTGATGA CGAAATGACC 
GGCTACGTGG CTACCCGGTG GTACAGAGCC CCCGAGATTA TGCTGAATTG GATGCACTAC 
AACCAGACAG TGGATATTTG GTCCGTGGGC TGCATCATGG CTGAGCTGTT GACCGGAAGA 
ACGTTGTTTC CTGGTACAGA CCATATTGAT CAGTTGAAGC TCATTTTAAG ACTCGTTGGA 
ACCCCAGGGG CTGAGCTTCT GAAGAAAATC TCCTCAGAGT CTCTGTCGAC CTGCTGGAAA 
AGATGCTGGT TTTGGACTCG GATAAGAGGA TCACAGCAGC CCAAGCTCTT GCGCATGCCT 
ACTTTGCTCA GTACCACGAC CCTGATGATG AGCCAGTGGC TGACCCTTAT GACCAGTCCT 
TTGAAAGCAG GGACCTCCTT ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Potential contribution of microRNA-125b targeting p38MAPK to relieving intermittent hypoxia-induced dementia of rat models.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia64234-241(2019 Jun)
Ren H,Qiu W,Lu Q,Peng C,Ding Y,Zhu B,Li Q,Chen X

Astragaloside IV ameliorates endoplasmic reticulum stress‑induced apoptosis of Aβ25‑35‑treated PC12 cells by inhibiting the p38 MAPK signaling pathway.
Molecular medicine reports19(3)2005-2012(2019 Mar)
Ma Y,Xiong L

p38-MAP Kinase Negatively Regulates the Slow Force Response to Stretch in Rat Myocardium through the Up-Regulation of Dual Specificity Phosphatase 6 (DUSP6).
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology52(2)172-185(2019)
Zavala MR,Díaz RG,Medina AJ,Acosta MP,Escudero DS,Ennis IL,Pérez NG,Villa-Abrille MC

Cigarette smoke extracts and cadmium induce COX-2 expression through γ-secretase-mediated p38 MAPK activation in C6 astroglia cells.
PloS one14(2)e0212749(2019)
Lim HJ,Park JH,Jo C,Yoon K,Koh YH

Reduced nicotinamide adenine dinucleotide phosphate inhibits rat platelet aggregation and p38 phosphorylation.
Thrombosis research171121-129(2018 11)
Gu Y,Sheng R,Wu J,Zhou Y,Qin ZH

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Mapk14 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

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