| Gene Symbol | Trib1 |
| Entrez Gene ID | 78969 |
| Full Name | tribbles pseudokinase 1 |
| Synonyms | Gig2 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | a nuclear factor; gene expression induced by m1-acetylcholine receptor [RGD, Feb 2006]. |
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Trib1 cDNA ORF clone, Rattus norvegicus(Norway rat)
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Gene
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Clones
gRNAs
The following Trib1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Trib1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID ORa06719 Clone ID Related Accession (Same CDS sequence) NM_023985.1 Accession Version NM_023985.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1119bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1527350400000 Organism Rattus norvegicus(Norway rat) Product tribbles homolog 1 Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AI601976.1, AW530250.1, BE096693.1, AF205438.1 and AA964141.1. On or before Jan 20, 2007 this sequence version replaced XM_343250.3, XM_001065461.1. ##Evidence-Data-START## Transcript exon combination :: AF205438.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081ATGCGGGTCG GTCCCGTGCG TTTTGCCCTG AGCGGCGCCT CGCAGCCCCG CGGACCGGCT
CTACTGTTCC CGGCTGCCCG GGGCACCCCG GCCAAACGCC TGCTGGACAC GGACGACGCG
GCGGCCGTGG CGGCCAAGTG TCCGCGCCTC TCTGAGTGCT CGAATCCCCC TGACTACCTC
AGTCCCCCCG GCTCGCCCTG CAGTCCTCAG CCTCCACCCT CGGCGCAGGG GACCGGCGGC
AGCTGTGTGA GCGCACCCGG GCCCAGCCGA ATCGCCGACT ACCTGCTGCT ACCCCTAGCT
GAGCGCGAGC ATGTGTCCCG GGCACTGTGC ATCCACACCG GCCGCGAGCT GCGCTGCAAG
GTGTTTCCCA TTAAACACTA CCAAGACAAA ATCAGGCCTT ACACCCAGCT GCCGTCCCAT
AGAAACATTA CTGGCATCGT GGAAGTGATC CTCGGGGAGA GCAAGGCCTA CGTTTTCTTT
GAGAAGGACT TTGGAGACAT GCACTCCTAT GTACGAAGCC GGAAAAGGCT TCGGGAAGAG
GAGGCCGCTC GGCTCTTCAA GCAAATTGTT TCCGCCGTTG CCCACTGCCA CCAGTCAGCC
ATTGTGCTGG GGGACCTGAA GCTTAGGAAA TTCGTCTTCT CCACAGAGGA GAGGACCCAG
CTTAGACTGG AAAGCCTAGA AGATACGCAC ATGATAAAGG GTGAAGATGA CGCATTGTCA
GATAAACATG GCTGCCCGGC CTATGTGAGC CCTGAGATCC TCAACACTAC TGGGACCTAC
TCCGGAAAGG CAGCGGATGT TTGGAGCCTT GGGGTGATGC TCTACACCCT TTTGGTCGGA
CGATACCCCT TTCATGACTC AGACCCGAGC GCCCTTTTCT CCAAAATCCG TCGGGGACAG
TTTTGCATTC CCGAGCATGT TTCCCCCAAA GCCAGGTGCC TCATCCGCAG CCTCCTGAGA
CGAGAACCTT CTGAGAGACT CACAGCTCCT GAGATCTTAC TCCATCCCTG GTTTGAATAC
GTCTTGGAAC CGGGGTATGT TGACTCAGAA GTAGGAACTT CTGACCAGAT TGTTCCCGAG
TACCAGGACG ACAATGACGT TAGTTCCTTT TTCTGCTAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_076475.1 CDS 605..1723 Translation 
Target ORF information:
RefSeq Version NM_023985.1 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus tribbles pseudokinase 1 (Trib1), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_023985.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081ATGCGGGTCG GTCCCGTGCG TTTTGCCCTG AGCGGCGCCT CGCAGCCCCG CGGACCGGCT
CTACTGTTCC CGGCTGCCCG GGGCACCCCG GCCAAACGCC TGCTGGACAC GGACGACGCG
GCGGCCGTGG CGGCCAAGTG TCCGCGCCTC TCTGAGTGCT CGAATCCCCC TGACTACCTC
AGTCCCCCCG GCTCGCCCTG CAGTCCTCAG CCTCCACCCT CGGCGCAGGG GACCGGCGGC
AGCTGTGTGA GCGCACCCGG GCCCAGCCGA ATCGCCGACT ACCTGCTGCT ACCCCTAGCT
GAGCGCGAGC ATGTGTCCCG GGCACTGTGC ATCCACACCG GCCGCGAGCT GCGCTGCAAG
GTGTTTCCCA TTAAACACTA CCAAGACAAA ATCAGGCCTT ACACCCAGCT GCCGTCCCAT
AGAAACATTA CTGGCATCGT GGAAGTGATC CTCGGGGAGA GCAAGGCCTA CGTTTTCTTT
GAGAAGGACT TTGGAGACAT GCACTCCTAT GTACGAAGCC GGAAAAGGCT TCGGGAAGAG
GAGGCCGCTC GGCTCTTCAA GCAAATTGTT TCCGCCGTTG CCCACTGCCA CCAGTCAGCC
ATTGTGCTGG GGGACCTGAA GCTTAGGAAA TTCGTCTTCT CCACAGAGGA GAGGACCCAG
CTTAGACTGG AAAGCCTAGA AGATACGCAC ATGATAAAGG GTGAAGATGA CGCATTGTCA
GATAAACATG GCTGCCCGGC CTATGTGAGC CCTGAGATCC TCAACACTAC TGGGACCTAC
TCCGGAAAGG CAGCGGATGT TTGGAGCCTT GGGGTGATGC TCTACACCCT TTTGGTCGGA
CGATACCCCT TTCATGACTC AGACCCGAGC GCCCTTTTCT CCAAAATCCG TCGGGGACAG
TTTTGCATTC CCGAGCATGT TTCCCCCAAA GCCAGGTGCC TCATCCGCAG CCTCCTGAGA
CGAGAACCTT CTGAGAGACT CACAGCTCCT GAGATCTTAC TCCATCCCTG GTTTGAATAC
GTCTTGGAAC CGGGGTATGT TGACTCAGAA GTAGGAACTT CTGACCAGAT TGTTCCCGAG
TACCAGGACG ACAATGACGT TAGTTCCTTT TTCTGCTAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages.
Nature495(7442)524-8(2013 Mar)
Satoh T,Kidoya H,Naito H,Yamamoto M,Takemura N,Nakagawa K,Yoshioka Y,Morii E,Takakura N,Takeuchi O,Akira S
Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia.
Blood116(8)1321-8(2010 Aug)
Dedhia PH,Keeshan K,Uljon S,Xu L,Vega ME,Shestova O,Zaks-Zilberman M,Romany C,Blacklow SC,Pear WS
Enhanced TLR-mediated NF-IL6 dependent gene expression by Trib1 deficiency.
The Journal of experimental medicine204(9)2233-9(2007 Sep)
Yamamoto M,Uematsu S,Okamoto T,Matsuura Y,Sato S,Kumar H,Satoh T,Saitoh T,Takeda K,Ishii KJ,Takeuchi O,Kawai T,Akira S
Human tribbles-1 controls proliferation and chemotaxis of smooth muscle cells via MAPK signaling pathways.
The Journal of biological chemistry282(25)18379-87(2007 Jun)
Sung HY,Guan H,Czibula A,King AR,Eder K,Heath E,Suvarna SK,Dower SK,Wilson AG,Francis SE,Crossman DC,Kiss-Toth E
Human tribbles, a protein family controlling mitogen-activated protein kinase cascades.
The Journal of biological chemistry279(41)42703-8(2004 Oct)
Kiss-Toth E,Bagstaff SM,Sung HY,Jozsa V,Dempsey C,Caunt JC,Oxley KM,Wyllie DH,Polgar T,Harte M,O'neill LA,Qwarnstrom EE,Dower SK
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