Enpep cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Enpep
Entrez Gene ID	64017
Full Name	glutamyl aminopeptidase
General protein information	Preferred Names glutamyl aminopeptidase Names glutamyl aminopeptidase AP-A EAP aminopeptidase A
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q42
Summary	ectoenzyme that selectively hydrolyzes acidic amino acid residues from the amino terminus of oligopeptides [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_022251.2	NP_071587.2	glutamyl aminopeptidase

Pathways from BioSystems

Homologies

Homo sapiens (human)	ENPEP	NP_001968.3
Macaca mulatta (Rhesus monkey)	ENPEP	XP_001090456.1
Mus musculus (house mouse)	Enpep	NP_031960.1
Drosophila melanogaster (fruit fly)	CG32473	NP_731786.1
Gallus gallus (chicken)	ENPEP	XP_426327.3
Xenopus tropicalis (tropical clawed frog)	enpep	XP_002934295.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003077	XP_003436384.1
Pan troglodytes (chimpanzee)	ENPEP	XP_517397.2
Canis lupus familiaris (dog)	ENPEP	XP_535696.2
Drosophila melanogaster (fruit fly)	CG8773	NP_650273.2
Drosophila melanogaster (fruit fly)	CG8774	NP_650274.2
Bos taurus (cattle)	ENPEP	NP_001033116.1
Rattus norvegicus (Norway rat)	Enpep	NP_071587.2
Danio rerio (zebrafish)	enpep	NP_001186660.1

Gene Ontology
Bibliography

Related articles in PubMed

Influence of thyroid disorders on the kidney expression and plasma activity of aminopeptidase A.
Wangensteen R, Segarra AB, Ramirez-Sanchez M, Gasparo MD, Dominguez G, Banegas I, Vargas F, Vives F, Prieto I
Endocrine regulations49(2)68-72(2015 Apr)

Structural insights into central hypertension regulation by human aminopeptidase A.
Yang Y, Liu C, Lin YL, Li F
The Journal of biological chemistry288(35)25638-45(2013 Aug)

The effect of recombinant aminopeptidase A (APA) on hypertension in pregnant spontaneously hypertensive rats (SHRs).
Ishii M, Hattori A, Numaguchi Y, Ma X, Nagasaka T, Tsujimoto M, Murohara T, Kobayashi H, Mizutani S
Early human development85(9)589-94(2009 Sep)

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)

Integral and associated lysosomal membrane proteins.
Schröder B, Wrocklage C, Pan C, Jäger R, Kösters B, Schäfer H, Elsässer HP, Mann M, Hasilik A
Traffic (Copenhagen, Denmark)8(12)1676-86(2007 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Enpep gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Enpep cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05544	NM_022251.2 Latest version!	Rattus norvegicus glutamyl aminopeptidase (Enpep), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Enpep ( NM_022251.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_071587.2 Rattus norvegicus glutamyl aminopeptidase (Enpep), mRNA.

Price & Availability↑

CloneID	ORa05544
Clone ID Related Accession (Same CDS sequence)	NM_022251.2
Accession Version	NM_022251.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2838bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1573660800000
Organism	Rattus norvegicus(Norway rat)
Product	glutamyl aminopeptidase
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF146044.1, CK481363.1, BC066663.1, CB747518.1 and AF214568.1. On Apr 5, 2007 this sequence version replaced NM_022251.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF214568.1, BC066663.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGAACTTTG CAGAGGAAGA GCCCTCTAAG AAATACTGCA TTAAAGGCAA ACACGTGGCC 
ATCATCTGCG CAACGGTGGT AGCAGTGGGA TTAATAGTAG GACTTTCTGT GGGCTTGACC 
AGGTCGTGTG AGCCGGGCAC AACCCCCGCT CCTTCCAACC CTCCTCCCCA CACCAGCACT 
GCCCTGCCTC CCCAGGATCA GAATGTCTGC CCTGACAGTG ACGATGAAAG TGGAGAATGG 
AAAAACTTCA GGCTGCCGGA CTTCATCCAG CCAGTTCACT ACGACCTGGA GGTGAAGGTC 
CTAATGGAGG AAGACAGGTA CACGGGCATA GTGAGCATCT CTGTCAACTT GAGCAAAGAC 
ACTCGTGACC TATGGCTGCA CATCAGGGAA ACCAGGATCA CCAAGCTGCC GGAGCTAAGG 
AGGCCCTCCG GGGAGCAGGT ACCGATTCGA CGGTGCTTTG AGTACAAGAA GCAGGAGTAC 
GTGGTGATTC AGGCTGAAGA AGACCTTGCG GCCACCAGCG GGGACAGTGT CTATCGGCTG 
ACCATAGAGT TTGAAGGCTG GTTGAACGGC TCCCTTGTGG GTTTTTACAG AACCACCTAC 
ACGGAGGACG GGCAAACCAA GAGCATAGCG GCCACTGACC ACGAACCAAC AGATGCCAGG 
AAGTCCTTCC CTTGTTTCGA TGAACCCAAC AAGAAGGCGA CTTACAACAT ATCCCTCATT 
CACCCGAAAG AATACTCAGC ACTTTCCAAT ATGCCAGTAG AGAAGGAAGA GACACTGGAT 
AACGACTGGA AGAAAACCAC TTTCATGAAG TCCGTCCCGA TGAGCACTTA CCTGGTGTGC 
TTTGCTGTAC ATCAGTTCAC CTCGATACAG AGAACATCCA GGAGTGGCAA ACCACTCACT 
GTTTACGTCC AGCCCAACCA AAAGCAAACA GCAGAGTATG CGGCAAACAT AACCAAAGCT 
GTGTTTGACT TCTTTGAAGA CTACTTCGCT ATGGAGTATT CTCTTCCGAA ACTGGATAAA 
ATTGCTATTC CAGATTTTGG CACCGGCGCC ATGGAAAACT GGGGACTTGT CACTTACCGA 
GAAACAAACC TGCTTTATGA CCCCCTGCTA TCGGCCTCAT CCAACCAGCA GAGAGTAGCC 
AGCGTGGTTG CCCACGAGCT CGTGCACCAG TGGTTTGGAA ATATCGTGAC CATGGACTGG 
TGGGACGACT TGTGGCTAAA TGAAGGATTT GCTTCGTTCT TCGAGTTCTT GGGAGTAAAC 
CACGCAGAAG CAGACTGGCA GATGCTCAGT CAGGTGCTGC TTGAAGACGT GCTACCTGTG 
CAGGAGGATG ACTCCCTGAT GTCCTCACAT CCGGTGGTTG TCACGGTGTC TACTCCAGCT 
GAAATAACGT CTGTGTTCGA TGGAATATCA TACAGCAAGG GAGCTTCTAT CCTGAGAATG 
CTTCAAGACT GGATAACACC AGAGAAATTC CAAAAGGGGT GTCAGATTTA CTTGGAAAAC 
TTCAAGTTCA AGAACGCGAA AACTTCCGAC TTTTGGGATT CACTGGAAAA GGCAAGTAAT 
CAACCAGTGA AAGAAGTAAT GGACACCTGG ACTAGCCAGA TGGGCTATCC TGTGGTTACT 
GTGAGTGGAA AGCAGAACGT CACCCAGAAA CGCTTTCTGT TGGACTACAA AGCTGACCCT 
TCCCAGCCAC CGTCAGCACT TGGTTACACA TGGAATATTC CAATCAAATG GACCGAAAAT 
GGCAATTCAA ATATCACAGT CTACTATAGG TCAAACAGAG AAGGAATCAC TTTGAATGCT 
AATCTTAGCG GAGATGGTTT TCTTAAAATA AACCCAGATC ACATTGGGTT TTATCGTGTA 
AACTATGAAG CAGAAACTTG GGATTGGATA GCTGAGACTC TCTCCTCAAA CCACATGAAC 
TTCTCTTCTG CTGACCGGTC AAGTTTTATC GATGATGCTT TTGCTCTGGC AAGAGCTCAA 
CTTCTGGATT ATGAGAAGGC CCTGAACTTG ACCAGGTATC TCACATCAGA AAAGGATTTC 
TTACCATGGG AGAGAGTCAT TTCAGCTGTA AGCTACATCA TTAGCATGTT TGAAGATGAC 
AGAGAGCTGT ACCCCCTGAT AGAGACATAC TTCCGAAGCC AAGTGAAGCC CATTGCGGAT 
TCTCTGGGAT GGCAGGATAC CGGAAGCCAC ATCACAAAGT TACTCCGGGC CTCTGTATTA 
GGATTCGCAT GCAAGATGGG AGCCGGAGAA GCCTTGGGCA ATGCTTCCCA GTTATTTGAG 
GCCTGGCTGA AAGGGAATGA AAGCATTCCT GTGAACCTCA GGCTGCTGGT GTATCGCTAT 
GGAATGCAGA ACTCTGGCAA TGAGGCAGCG TGGAACTATA CTCTAGAGCA GTACCAGAAA 
ACATCTCTAG CACAAGAGAA AGAAAAGCTG CTCTATGGGT TAGCTTCGGT GAAGGATGTT 
ACACTCTTGG CAAGGTATCT GGAAATGCTC AAAGACCCCA ATATTATTAA AACTCAGGAC 
GTATTTACAG TCATCCGCTA CATCTCCTAC AACAGCTATG GGAAAAGCAT GGCCTGGAAC 
TGGATCCAAC TCAACTGGGA CTATCTGGTC AACAGATTTA CAATCAACGA CAGATACCTT 
GGCCGGATCG TCACCATAGC CGAGCCCTTC AACACTGAGC TGCAGCTCTG GCAGATGCAG 
AGCTTCTTTG CAAAATATCC AAATGCTGGC GCTGGAGCAA AACCCAGAGA GCAAGTGCTG 
GAAACGGTGA AGAACAACAT CGAGTGGCTA AAACTGAACA GAAAGTCCAT CAGCGAGTGG 
TTCACCAGCA TGCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071587.2
CDS	422..3259
Translation	MNFAEEEPSKKYCIKGKHVAIICATVVAVGLIVGLSVGLTRSCEPGTTPAPSNPPPHTSTALPPQDQNVCPDSDDESGEWKNFRLPDFIQPVHYDLEVKVLMEEDRYTGIVSISVNLSKDTRDLWLHIRETRITKLPELRRPSGEQVPIRRCFEYKKQEYVVIQAEEDLAATSGDSVYRLTIEFEGWLNGSLVGFYRTTYTEDGQTKSIAATDHEPTDARKSFPCFDEPNKKATYNISLIHPKEYSALSNMPVEKEETLDNDWKKTTFMKSVPMSTYLVCFAVHQFTSIQRTSRSGKPLTVYVQPNQKQTAEYAANITKAVFDFFEDYFAMEYSLPKLDKIAIPDFGTGAMENWGLVTYRETNLLYDPLLSASSNQQRVASVVAHELVHQWFGNIVTMDWWDDLWLNEGFASFFEFLGVNHAEADWQMLSQVLLEDVLPVQEDDSLMSSHPVVVTVSTPAEITSVFDGISYSKGASILRMLQDWITPEKFQKGCQIYLENFKFKNAKTSDFWDSLEKASNQPVKEVMDTWTSQMGYPVVTVSGKQNVTQKRFLLDYKADPSQPPSALGYTWNIPIKWTENGNSNITVYYRSNREGITLNANLSGDGFLKINPDHIGFYRVNYEAETWDWIAETLSSNHMNFSSADRSSFIDDAFALARAQLLDYEKALNLTRYLTSEKDFLPWERVISAVSYIISMFEDDRELYPLIETYFRSQVKPIADSLGWQDTGSHITKLLRASVLGFACKMGAGEALGNASQLFEAWLKGNESIPVNLRLLVYRYGMQNSGNEAAWNYTLEQYQKTSLAQEKEKLLYGLASVKDVTLLARYLEMLKDPNIIKTQDVFTVIRYISYNSYGKSMAWNWIQLNWDYLVNRFTINDRYLGRIVTIAEPFNTELQLWQMQSFFAKYPNAGAGAKPREQVLETVKNNIEWLKLNRKSISEWFTSMP

Target ORF information:

RefSeq Version	NM_022251.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus glutamyl aminopeptidase (Enpep), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022251.2

ORF Insert Sequence:

ATGAACTTTG CAGAGGAAGA GCCCTCTAAG AAATACTGCA TTAAAGGCAA ACACGTGGCC 
ATCATCTGCG CAACGGTGGT AGCAGTGGGA TTAATAGTAG GACTTTCTGT GGGCTTGACC 
AGGTCGTGTG AGCCGGGCAC AACCCCCGCT CCTTCCAACC CTCCTCCCCA CACCAGCACT 
GCCCTGCCTC CCCAGGATCA GAATGTCTGC CCTGACAGTG ACGATGAAAG TGGAGAATGG 
AAAAACTTCA GGCTGCCGGA CTTCATCCAG CCAGTTCACT ACGACCTGGA GGTGAAGGTC 
CTAATGGAGG AAGACAGGTA CACGGGCATA GTGAGCATCT CTGTCAACTT GAGCAAAGAC 
ACTCGTGACC TATGGCTGCA CATCAGGGAA ACCAGGATCA CCAAGCTGCC GGAGCTAAGG 
AGGCCCTCCG GGGAGCAGGT ACCGATTCGA CGGTGCTTTG AGTACAAGAA GCAGGAGTAC 
GTGGTGATTC AGGCTGAAGA AGACCTTGCG GCCACCAGCG GGGACAGTGT CTATCGGCTG 
ACCATAGAGT TTGAAGGCTG GTTGAACGGC TCCCTTGTGG GTTTTTACAG AACCACCTAC 
ACGGAGGACG GGCAAACCAA GAGCATAGCG GCCACTGACC ACGAACCAAC AGATGCCAGG 
AAGTCCTTCC CTTGTTTCGA TGAACCCAAC AAGAAGGCGA CTTACAACAT ATCCCTCATT 
CACCCGAAAG AATACTCAGC ACTTTCCAAT ATGCCAGTAG AGAAGGAAGA GACACTGGAT 
AACGACTGGA AGAAAACCAC TTTCATGAAG TCCGTCCCGA TGAGCACTTA CCTGGTGTGC 
TTTGCTGTAC ATCAGTTCAC CTCGATACAG AGAACATCCA GGAGTGGCAA ACCACTCACT 
GTTTACGTCC AGCCCAACCA AAAGCAAACA GCAGAGTATG CGGCAAACAT AACCAAAGCT 
GTGTTTGACT TCTTTGAAGA CTACTTCGCT ATGGAGTATT CTCTTCCGAA ACTGGATAAA 
ATTGCTATTC CAGATTTTGG CACCGGCGCC ATGGAAAACT GGGGACTTGT CACTTACCGA 
GAAACAAACC TGCTTTATGA CCCCCTGCTA TCGGCCTCAT CCAACCAGCA GAGAGTAGCC 
AGCGTGGTTG CCCACGAGCT CGTGCACCAG TGGTTTGGAA ATATCGTGAC CATGGACTGG 
TGGGACGACT TGTGGCTAAA TGAAGGATTT GCTTCGTTCT TCGAGTTCTT GGGAGTAAAC 
CACGCAGAAG CAGACTGGCA GATGCTCAGT CAGGTGCTGC TTGAAGACGT GCTACCTGTG 
CAGGAGGATG ACTCCCTGAT GTCCTCACAT CCGGTGGTTG TCACGGTGTC TACTCCAGCT 
GAAATAACGT CTGTGTTCGA TGGAATATCA TACAGCAAGG GAGCTTCTAT CCTGAGAATG 
CTTCAAGACT GGATAACACC AGAGAAATTC CAAAAGGGGT GTCAGATTTA CTTGGAAAAC 
TTCAAGTTCA AGAACGCGAA AACTTCCGAC TTTTGGGATT CACTGGAAAA GGCAAGTAAT 
CAACCAGTGA AAGAAGTAAT GGACACCTGG ACTAGCCAGA TGGGCTATCC TGTGGTTACT 
GTGAGTGGAA AGCAGAACGT CACCCAGAAA CGCTTTCTGT TGGACTACAA AGCTGACCCT 
TCCCAGCCAC CGTCAGCACT TGGTTACACA TGGAATATTC CAATCAAATG GACCGAAAAT 
GGCAATTCAA ATATCACAGT CTACTATAGG TCAAACAGAG AAGGAATCAC TTTGAATGCT 
AATCTTAGCG GAGATGGTTT TCTTAAAATA AACCCAGATC ACATTGGGTT TTATCGTGTA 
AACTATGAAG CAGAAACTTG GGATTGGATA GCTGAGACTC TCTCCTCAAA CCACATGAAC 
TTCTCTTCTG CTGACCGGTC AAGTTTTATC GATGATGCTT TTGCTCTGGC AAGAGCTCAA 
CTTCTGGATT ATGAGAAGGC CCTGAACTTG ACCAGGTATC TCACATCAGA AAAGGATTTC 
TTACCATGGG AGAGAGTCAT TTCAGCTGTA AGCTACATCA TTAGCATGTT TGAAGATGAC 
AGAGAGCTGT ACCCCCTGAT AGAGACATAC TTCCGAAGCC AAGTGAAGCC CATTGCGGAT 
TCTCTGGGAT GGCAGGATAC CGGAAGCCAC ATCACAAAGT TACTCCGGGC CTCTGTATTA 
GGATTCGCAT GCAAGATGGG AGCCGGAGAA GCCTTGGGCA ATGCTTCCCA GTTATTTGAG 
GCCTGGCTGA AAGGGAATGA AAGCATTCCT GTGAACCTCA GGCTGCTGGT GTATCGCTAT 
GGAATGCAGA ACTCTGGCAA TGAGGCAGCG TGGAACTATA CTCTAGAGCA GTACCAGAAA 
ACATCTCTAG CACAAGAGAA AGAAAAGCTG CTCTATGGGT TAGCTTCGGT GAAGGATGTT 
ACACTCTTGG CAAGGTATCT GGAAATGCTC AAAGACCCCA ATATTATTAA AACTCAGGAC 
GTATTTACAG TCATCCGCTA CATCTCCTAC AACAGCTATG GGAAAAGCAT GGCCTGGAAC 
TGGATCCAAC TCAACTGGGA CTATCTGGTC AACAGATTTA CAATCAACGA CAGATACCTT 
GGCCGGATCG TCACCATAGC CGAGCCCTTC AACACTGAGC TGCAGCTCTG GCAGATGCAG 
AGCTTCTTTG CAAAATATCC AAATGCTGGC GCTGGAGCAA AACCCAGAGA GCAAGTGCTG 
GAAACGGTGA AGAACAACAT CGAGTGGCTA AAACTGAACA GAAAGTCCAT CAGCGAGTGG 
TTCACCAGCA TGCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Influence of thyroid disorders on the kidney expression and plasma activity of aminopeptidase A.
Endocrine regulations49(2)68-72(2015 Apr)
Wangensteen R,Segarra AB,Ramirez-Sanchez M,Gasparo MD,Dominguez G,Banegas I,Vargas F,Vives F,Prieto I

Structural insights into central hypertension regulation by human aminopeptidase A.
The Journal of biological chemistry288(35)25638-45(2013 Aug)
Yang Y,Liu C,Lin YL,Li F

The effect of recombinant aminopeptidase A (APA) on hypertension in pregnant spontaneously hypertensive rats (SHRs).
Early human development85(9)589-94(2009 Sep)
Ishii M,Hattori A,Numaguchi Y,Ma X,Nagasaka T,Tsujimoto M,Murohara T,Kobayashi H,Mizutani S

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)
Gonzales PA,Pisitkun T,Hoffert JD,Tchapyjnikov D,Star RA,Kleta R,Wang NS,Knepper MA

Integral and associated lysosomal membrane proteins.
Traffic (Copenhagen, Denmark)8(12)1676-86(2007 Dec)
Schröder B,Wrocklage C,Pan C,Jäger R,Kösters B,Schäfer H,Elsässer HP,Mann M,Hasilik A

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

Enpep cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM