Smc1a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Smc1a
Entrez Gene ID	63996
Full Name	structural maintenance of chromosomes 1A
Synonyms	SB1.8,SMC-1A,Smc1l1
General protein information	Preferred Names structural maintenance of chromosomes 1A Names structural maintenance of chromosomes protein 1A DXhXs423e SMC (segregation of mitotic chromosomes 1)-like 1 SMC protein 1A SMC-like 1 SMC-protein segregation of mitotic chromosomes-like 1 structural maintenance of chromosomes 1 like 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq13
Summary	structural maintenance of chromosomes (SMC) protein, one of 2 component proteins forming the cohesin multiprotein complex required for sister chromatid cohesion; thought to be a component of functional kinetochores [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031683.1	NP_113871.1	structural maintenance of chromosomes protein 1A

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SMC1A	XP_538049.3
Danio rerio (zebrafish)	smc1a	NP_001155103.1
Schizosaccharomyces pombe (fission yeast)	psm1	NP_596049.2
Mus musculus (house mouse)	Smc1a	NP_062684.2
Caenorhabditis elegans (roundworm)	him-1	NP_001040658.2
Macaca mulatta (Rhesus monkey)	SMC1A	XP_001091228.1
Arabidopsis thaliana (thale cress)	TTN8	NP_001190092.1
Oryza sativa (rice)	Os12g0641500	NP_001067404.1
Kluyveromyces lactis	KLLA0D07502g	XP_453397.1
Eremothecium gossypii	AGOS_AGL023W	NP_986643.1
Danio rerio (zebrafish)	smc1al	NP_997975.2
Saccharomyces cerevisiae (baker's yeast)	SMC1	NP_116647.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002947	XP_311953.3
Magnaporthe oryzae (rice blast fungus)	MGG_16203	XP_003709622.1
Homo sapiens (human)	SMC1A	NP_006297.2
Pan troglodytes (chimpanzee)	SMC1A	XP_003954052.1
Bos taurus (cattle)	SMC1A	NP_777039.1
Rattus norvegicus (Norway rat)	Smc1a	NP_113871.1
Gallus gallus (chicken)	SMC1A	NP_989847.1
Drosophila melanogaster (fruit fly)	SMC1	NP_651211.2
Neurospora crassa	NCU01323	XP_961409.2
Xenopus tropicalis (tropical clawed frog)	LOC100493711	XP_002935560.1

Gene Ontology
Bibliography

Related articles in PubMed

Knocking down SMC1A inhibits growth and leads to G2/M arrest in human glioma cells.
Ma Z, Lin M, Li K, Fu Y, Liu X, Yang D, Zhao Y, Zheng J, Sun B
International journal of clinical and experimental pathology6(5)862-9(2013)

In vitro loading of human cohesin on DNA by the human Scc2-Scc4 loader complex.
Bermudez VP, Farina A, Higashi TL, Du F, Tappin I, Takahashi TS, Hurwitz J
Proceedings of the National Academy of Sciences of the United States of America109(24)9366-71(2012 Jun)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanhäusser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

A unique role of cohesin-SA1 in gene regulation and development.
Remeseiro S, Cuadrado A, Gómez-López G, Pisano DG, Losada A
The EMBO journal31(9)2090-102(2012 May)

Identification and molecular characterization of the mammalian α-kleisin RAD21L.
Gutiérrez-Caballero C, Herrán Y, Sánchez-Martín M, Suja JA, Barbero JL, Llano E, Pendás AM
Cell cycle (Georgetown, Tex.)10(9)1477-87(2011 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Smc1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Smc1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa08464	NM_031683.1 Latest version!	Rattus norvegicus structural maintenance of chromosomes 1A (Smc1a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Smc1a ( NM_031683.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_113871.1 Rattus norvegicus structural maintenance of chromosomes 1A (Smc1a), mRNA.

Price & Availability↑

CloneID	ORa08464
Clone ID Related Accession (Same CDS sequence)	NM_031683.1
Accession Version	NM_031683.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3702bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550160000000
Organism	Rattus norvegicus(Norway rat)
Product	structural maintenance of chromosomes protein 1A
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ005113.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ005113.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGGTTTCC TGAAACTGAT TGAGATTGAG AACTTTAAAT CGTACAAGGG TCGACAAATT 
ATCGGACCAT TTCAGAGGTT CACCGCCATC ATTGGACCCA ATGGCTCTGG TAAGTCAAAT 
CTCATGGATG CCATCAGCTT TGTGCTTGGT GAAAAAACCA GCAACCTGAG GGTAAAGACC 
CTGAGGGACC TGATACACGG AGCTCCTGTG GGCAAGCCGG CTGCCAACCG AGCCTTTGTC 
AGCATGGTCT ACTCCGAGGA GGGTGCTGAG GACCGCACCT TTGCCCGAGT CATTGTAGGG 
GGCTCTTCTG AGTACAAGAT CAATAACAAA GTTGTCCAGC TACATGAATA CAGTGAAGAG 
TTAGAGAAGT TGGGCATTCT CATCAAAGCT CGTAACTTCC TCGTCTTCCA GGGTGCAGTG 
GAATCTATTG CCATGAAGAA CCCCAAGGAG AGGACAGCTT TATTTGAAGA AATTAGTCGC 
TCTGGGGAAC TTGCACAGGA GTATGACAAG CGAAAGAAAG AAATGGTGAA GGCTGAAGAA 
GACACACAGT TTAATTATCA TCGCAAGAAA AATATTGCAG CTGAACGCAA GGAGGCCAAA 
CAAGAAAAGG AAGAGGCTGA CCGCTACCAG GCCCTGAAGG ATGAGGTAGT ACGCGCACAG 
GTACAATTGC AGCTTTTTAA ACTCTACCAC AACGAAGTGG AGATTGAGAA GCTCAACAAG 
GAACTGGCCT CGAAGAACAA GGAAATTGAG AAGGACAAAA AGCGGATGGA CAAGGTAGAG 
GATGAACTGA AGGAGAAGAA GAAAGAGCTG GGCAAAATGA TGCGGGAACA GCAGCAGATT 
GAGAAGGAGA TCAAGGAAAA GGACTCAGAA TTGAATCAGA AGAGGCCTCA GTACATCAAA 
GCAAAAGAGA ATACATCCCA CAAAATCAAG AAGCTTGAAG CAGCCAAGAA ATCTCTGCAG 
AATCGTCAGA AACATTATAA GAAACGTAAA GGTGACATGG ATGAGCTGGA GAAAGAGATG 
CTGTCAGTGG AGAAGGCCCG ACAGGAGTTT GAAGAGCGGA TGGAGGAAGA GAGTCAGAGT 
CAAGGCAGAG ACTTGACCCT GGAGGAGAAC CAGGTAAAGA AATACCACCG ATTAAAAGAG 
GAAGCTAGCA AGAGAGCAGC CACTTTGGCT CAGGAGCTGG AGAAGTTTAA TCGAGACCAG 
AAAGCTGACC AGGACCGTCT AGATCTAGAA GAGCGGAAGA AAGTAGAGAC AGAGGCCAAG 
ATCAAGCAAA AACTGCGGGA GATTGAAGAG AATCAGAAAC GGATTGAGAA GCTAGAGGAA 
TATATTACCA CTAGCAAGCA GTCTCTAGAG GAACAGAAGA AGCTAGAGGG AGAATTGACA 
GAAGAAGTAG AGATGGCCAA GCGTCGTATT GATGAGATCA ATAAGGAGCT GAACCAGGTG 
ATGGAGCAAT TGGGGGATGC GCGCATTGAC CGGCAGGAGA GCAGCCGCCA GCAGAGGAAG 
GCAGAAATAA TGGAAAGCAT CAAGCGTCTC TACCCTGGTT CTGTGTATGG CCGCCTCATT 
GACCTCTGCC AGCCTACACA AAAGAAGTAT CAGATTGCTG TGACCAAGGT TTTAGGAAAG 
AACATGGATG CTATTATTGT AGACTCCGAG AAGACAGGTC GGGATTGTAT TCAGTATATC 
AAGGAGCAAC GTGGAGAGCC TGAGACCTTC TTGCCTCTTG ACTACCTGGA GGTGAAACCT 
ACTGATGAGA AACTCCGAGA ACTGAAGGGG GCCAAGCTAG TGATTGATGT GATTCGCTAT 
GAGCCACCTC ACATCAAAAA AGCTCTGCAG TATGCTTGTG GCAATGCCCT TGTTTGTGAC 
AATGTGGAGG ATGCGCGACG AATTGCCTTT GGAGGTCACC AACGCCACAA GACAGTGGCA 
TTGGATGGCA CCCTGTTCCA GAAGTCAGGA GTTATCTCTG GTGGAGCCAG TGATCTCAAG 
GCAAAGGCAC GACGCTGGGA TGAGAAGGCA GTAGACAAAC TAAAAGAAAA AAAAGAACGT 
TTGACGGAGG AGCTAAAAGA GCAGATGAAG GCAAAACGAA AAGAGGCAGA GCTGCGTCAG 
GTGCAGTCTC AGGCCCATGG GCTACAAATG CGGCTGAAGT ACTCACAGAG TGACCTAGAA 
CAGACTAAGA CAAGGCATCT TGCCCTGAAT CTCCAGGAAA AATCTAAGCT GGAGAGTGAA 
CTAGCCAACT TCGGGCCTCG AATTAATGAT ATCAAGAGAA TCATACAGAG CCGAGAGAGG 
GAAATGAAAG ACTTGAAGGA GAAGATGAAC CAGGTGGAAG ATGAGGTGTT TGAAGAGTTT 
TGTCGGGAGA TTGGTGTGCG TAACATCCGC GAATTTGAGG AAGAAAAGGT GAAGCGGCAG 
AATGAAATTG CCAAGAAACG CTTGGAATTT GAGAATCAGA AGACTCGCTT GGGCATCCAG 
TTGGATTTTG AAAAGAATCA GTTGAAGGAG GACCAGGATA AAGTACACAT GTGGGAGCAG 
ACAGTAAAAA AGGATGAAAA TGAGATAGAA AAGCTTAAGA AGGAGGAGCA AAGACACATG 
AAGATAATAG ATGAAACCAT GGCTCAGCTC CAAGACCTTA AGAATCAGCA CCTGGCCAAA 
AAGTCAGAAG TGAATGACAA GAATCATGAG ATGGAAGAAA TTCGCAAGAA GCTTGGGGGT 
GCCAATAAGG AAATGACTCA CTTACAGAAG GAAGTGACAG CCATTGAGAC CAAGCTTGAA 
CAGAAGCGCA GTGACCGCCA CAACCTGCTA CAGGCCTGTA AGATGCAGGA CATCAAATTG 
CCACTGTCAA AGGGCACCAT GGATGATATT AGTCAGGAAG AAGGTGGCTC CCAGGGAGAA 
GAGTCAGTGA GTGGTTCCCA GAGAACATCT AGTATCTATG CACGAGAGGC CCTCATTGAG 
ATTGACTACG GTGACCTGTG TGAAGATCTG AAGGATGCAC AGGCGGAAGA AGAAATCAAG 
CAAGAGATGA ACACACTCCA GCAAAAGCTG AATGAGCAGC AGAGTGTGCT TCAGAGGATT 
GCTGCCCCTA ACATGAAGGC CATGGAAAAG CTGGAAAGTG TCCGAGACAA GTTCCAGGAG 
ACCTCAGATG AATTTGAGGC AGCACGAAAG CGAGCAAAGA AAGCCAAGCA GGCATTTGAA 
CAGATAAAGA AGGAGCGCTT TGACCGATTC AATGCTTGTT TTGAATCTGT GGCTACCAAT 
ATTGATGAGA TCTACAAGGC TCTGTCCCGT AACAGCAGTG CCCAGGCATT CTTGGGCCCC 
GAGAATCCTG AAGAGCCCTA TTTGGATGGT ATCAACTACA ACTGTGTAGC TCCTGGCAAA 
CGTTTCCGGC CTATGGACAA TTTGTCAGGC GGGGAGAAGA CAGTTGCCGC ACTGGCCTTG 
CTTTTTGCCA TTCACAGCTA CAAGCCAGCC CCCTTCTTCG TCCTGGATGA GATTGATGCT 
GCCTTGGATA ACACCAACAT TGGCAAGGTG GCAAATTACA TCAAGGAGCA GTCAACTTGC 
AACTTCCAGG CCATTGTTAT CTCTCTCAAG GAGGAATTCT ACACCAAGGC TGAGAGCCTC 
ATTGGAGTCT ATCCTGAGCA AGGAGACTGT GTGATCAGCA AAGTCCTGAC CTTCGACCTC 
ACCAAGTATC CAGATGCCAA CCCTAACCCC AATGAACAAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113871.1
CDS	52..3753
Translation	MGFLKLIEIENFKSYKGRQIIGPFQRFTAIIGPNGSGKSNLMDAISFVLGEKTSNLRVKTLRDLIHGAPVGKPAANRAFVSMVYSEEGAEDRTFARVIVGGSSEYKINNKVVQLHEYSEELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQALKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNRQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELKGAKLVIDVIRYEPPHIKKALQYACGNALVCDNVEDARRIAFGGHQRHKTVALDGTLFQKSGVISGGASDLKAKARRWDEKAVDKLKEKKERLTEELKEQMKAKRKEAELRQVQSQAHGLQMRLKYSQSDLEQTKTRHLALNLQEKSKLESELANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVKRQNEIAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGGSQGEESVSGSQRTSSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAMEKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKERFDRFNACFESVATNIDEIYKALSRNSSAQAFLGPENPEEPYLDGINYNCVAPGKRFRPMDNLSGGEKTVAALALLFAIHSYKPAPFFVLDEIDAALDNTNIGKVANYIKEQSTCNFQAIVISLKEEFYTKAESLIGVYPEQGDCVISKVLTFDLTKYPDANPNPNEQ

Target ORF information:

RefSeq Version	NM_031683.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus structural maintenance of chromosomes 1A (Smc1a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031683.1

ORF Insert Sequence:

ATGGGTTTCC TGAAACTGAT TGAGATTGAG AACTTTAAAT CGTACAAGGG TCGACAAATT 
ATCGGACCAT TTCAGAGGTT CACCGCCATC ATTGGACCCA ATGGCTCTGG TAAGTCAAAT 
CTCATGGATG CCATCAGCTT TGTGCTTGGT GAAAAAACCA GCAACCTGAG GGTAAAGACC 
CTGAGGGACC TGATACACGG AGCTCCTGTG GGCAAGCCGG CTGCCAACCG AGCCTTTGTC 
AGCATGGTCT ACTCCGAGGA GGGTGCTGAG GACCGCACCT TTGCCCGAGT CATTGTAGGG 
GGCTCTTCTG AGTACAAGAT CAATAACAAA GTTGTCCAGC TACATGAATA CAGTGAAGAG 
TTAGAGAAGT TGGGCATTCT CATCAAAGCT CGTAACTTCC TCGTCTTCCA GGGTGCAGTG 
GAATCTATTG CCATGAAGAA CCCCAAGGAG AGGACAGCTT TATTTGAAGA AATTAGTCGC 
TCTGGGGAAC TTGCACAGGA GTATGACAAG CGAAAGAAAG AAATGGTGAA GGCTGAAGAA 
GACACACAGT TTAATTATCA TCGCAAGAAA AATATTGCAG CTGAACGCAA GGAGGCCAAA 
CAAGAAAAGG AAGAGGCTGA CCGCTACCAG GCCCTGAAGG ATGAGGTAGT ACGCGCACAG 
GTACAATTGC AGCTTTTTAA ACTCTACCAC AACGAAGTGG AGATTGAGAA GCTCAACAAG 
GAACTGGCCT CGAAGAACAA GGAAATTGAG AAGGACAAAA AGCGGATGGA CAAGGTAGAG 
GATGAACTGA AGGAGAAGAA GAAAGAGCTG GGCAAAATGA TGCGGGAACA GCAGCAGATT 
GAGAAGGAGA TCAAGGAAAA GGACTCAGAA TTGAATCAGA AGAGGCCTCA GTACATCAAA 
GCAAAAGAGA ATACATCCCA CAAAATCAAG AAGCTTGAAG CAGCCAAGAA ATCTCTGCAG 
AATCGTCAGA AACATTATAA GAAACGTAAA GGTGACATGG ATGAGCTGGA GAAAGAGATG 
CTGTCAGTGG AGAAGGCCCG ACAGGAGTTT GAAGAGCGGA TGGAGGAAGA GAGTCAGAGT 
CAAGGCAGAG ACTTGACCCT GGAGGAGAAC CAGGTAAAGA AATACCACCG ATTAAAAGAG 
GAAGCTAGCA AGAGAGCAGC CACTTTGGCT CAGGAGCTGG AGAAGTTTAA TCGAGACCAG 
AAAGCTGACC AGGACCGTCT AGATCTAGAA GAGCGGAAGA AAGTAGAGAC AGAGGCCAAG 
ATCAAGCAAA AACTGCGGGA GATTGAAGAG AATCAGAAAC GGATTGAGAA GCTAGAGGAA 
TATATTACCA CTAGCAAGCA GTCTCTAGAG GAACAGAAGA AGCTAGAGGG AGAATTGACA 
GAAGAAGTAG AGATGGCCAA GCGTCGTATT GATGAGATCA ATAAGGAGCT GAACCAGGTG 
ATGGAGCAAT TGGGGGATGC GCGCATTGAC CGGCAGGAGA GCAGCCGCCA GCAGAGGAAG 
GCAGAAATAA TGGAAAGCAT CAAGCGTCTC TACCCTGGTT CTGTGTATGG CCGCCTCATT 
GACCTCTGCC AGCCTACACA AAAGAAGTAT CAGATTGCTG TGACCAAGGT TTTAGGAAAG 
AACATGGATG CTATTATTGT AGACTCCGAG AAGACAGGTC GGGATTGTAT TCAGTATATC 
AAGGAGCAAC GTGGAGAGCC TGAGACCTTC TTGCCTCTTG ACTACCTGGA GGTGAAACCT 
ACTGATGAGA AACTCCGAGA ACTGAAGGGG GCCAAGCTAG TGATTGATGT GATTCGCTAT 
GAGCCACCTC ACATCAAAAA AGCTCTGCAG TATGCTTGTG GCAATGCCCT TGTTTGTGAC 
AATGTGGAGG ATGCGCGACG AATTGCCTTT GGAGGTCACC AACGCCACAA GACAGTGGCA 
TTGGATGGCA CCCTGTTCCA GAAGTCAGGA GTTATCTCTG GTGGAGCCAG TGATCTCAAG 
GCAAAGGCAC GACGCTGGGA TGAGAAGGCA GTAGACAAAC TAAAAGAAAA AAAAGAACGT 
TTGACGGAGG AGCTAAAAGA GCAGATGAAG GCAAAACGAA AAGAGGCAGA GCTGCGTCAG 
GTGCAGTCTC AGGCCCATGG GCTACAAATG CGGCTGAAGT ACTCACAGAG TGACCTAGAA 
CAGACTAAGA CAAGGCATCT TGCCCTGAAT CTCCAGGAAA AATCTAAGCT GGAGAGTGAA 
CTAGCCAACT TCGGGCCTCG AATTAATGAT ATCAAGAGAA TCATACAGAG CCGAGAGAGG 
GAAATGAAAG ACTTGAAGGA GAAGATGAAC CAGGTGGAAG ATGAGGTGTT TGAAGAGTTT 
TGTCGGGAGA TTGGTGTGCG TAACATCCGC GAATTTGAGG AAGAAAAGGT GAAGCGGCAG 
AATGAAATTG CCAAGAAACG CTTGGAATTT GAGAATCAGA AGACTCGCTT GGGCATCCAG 
TTGGATTTTG AAAAGAATCA GTTGAAGGAG GACCAGGATA AAGTACACAT GTGGGAGCAG 
ACAGTAAAAA AGGATGAAAA TGAGATAGAA AAGCTTAAGA AGGAGGAGCA AAGACACATG 
AAGATAATAG ATGAAACCAT GGCTCAGCTC CAAGACCTTA AGAATCAGCA CCTGGCCAAA 
AAGTCAGAAG TGAATGACAA GAATCATGAG ATGGAAGAAA TTCGCAAGAA GCTTGGGGGT 
GCCAATAAGG AAATGACTCA CTTACAGAAG GAAGTGACAG CCATTGAGAC CAAGCTTGAA 
CAGAAGCGCA GTGACCGCCA CAACCTGCTA CAGGCCTGTA AGATGCAGGA CATCAAATTG 
CCACTGTCAA AGGGCACCAT GGATGATATT AGTCAGGAAG AAGGTGGCTC CCAGGGAGAA 
GAGTCAGTGA GTGGTTCCCA GAGAACATCT AGTATCTATG CACGAGAGGC CCTCATTGAG 
ATTGACTACG GTGACCTGTG TGAAGATCTG AAGGATGCAC AGGCGGAAGA AGAAATCAAG 
CAAGAGATGA ACACACTCCA GCAAAAGCTG AATGAGCAGC AGAGTGTGCT TCAGAGGATT 
GCTGCCCCTA ACATGAAGGC CATGGAAAAG CTGGAAAGTG TCCGAGACAA GTTCCAGGAG 
ACCTCAGATG AATTTGAGGC AGCACGAAAG CGAGCAAAGA AAGCCAAGCA GGCATTTGAA 
CAGATAAAGA AGGAGCGCTT TGACCGATTC AATGCTTGTT TTGAATCTGT GGCTACCAAT 
ATTGATGAGA TCTACAAGGC TCTGTCCCGT AACAGCAGTG CCCAGGCATT CTTGGGCCCC 
GAGAATCCTG AAGAGCCCTA TTTGGATGGT ATCAACTACA ACTGTGTAGC TCCTGGCAAA 
CGTTTCCGGC CTATGGACAA TTTGTCAGGC GGGGAGAAGA CAGTTGCCGC ACTGGCCTTG 
CTTTTTGCCA TTCACAGCTA CAAGCCAGCC CCCTTCTTCG TCCTGGATGA GATTGATGCT 
GCCTTGGATA ACACCAACAT TGGCAAGGTG GCAAATTACA TCAAGGAGCA GTCAACTTGC 
AACTTCCAGG CCATTGTTAT CTCTCTCAAG GAGGAATTCT ACACCAAGGC TGAGAGCCTC 
ATTGGAGTCT ATCCTGAGCA AGGAGACTGT GTGATCAGCA AAGTCCTGAC CTTCGACCTC 
ACCAAGTATC CAGATGCCAA CCCTAACCCC AATGAACAAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Knocking down SMC1A inhibits growth and leads to G2/M arrest in human glioma cells.
International journal of clinical and experimental pathology6(5)862-9(2013)
Ma Z,Lin M,Li K,Fu Y,Liu X,Yang D,Zhao Y,Zheng J,Sun B

In vitro loading of human cohesin on DNA by the human Scc2-Scc4 loader complex.
Proceedings of the National Academy of Sciences of the United States of America109(24)9366-71(2012 Jun)
Bermudez VP,Farina A,Higashi TL,Du F,Tappin I,Takahashi TS,Hurwitz J

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanhäusser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

A unique role of cohesin-SA1 in gene regulation and development.
The EMBO journal31(9)2090-102(2012 May)
Remeseiro S,Cuadrado A,Gómez-López G,Pisano DG,Losada A

Identification and molecular characterization of the mammalian α-kleisin RAD21L.
Cell cycle (Georgetown, Tex.)10(9)1477-87(2011 May)
Gutiérrez-Caballero C,Herrán Y,Sánchez-Martín M,Suja JA,Barbero JL,Llano E,Pendás AM

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Smc1a cDNA ORF clone, Rattus norvegicus(Norway rat)

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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