Gnb3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gnb3
Entrez Gene ID	60449
Full Name	G protein subunit beta 3
General protein information	Preferred Names G protein subunit beta 3 Names guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 G protein beta-subunit guanine nucleotide binding protein (G protein), beta 3 guanine nucleotide binding protein (G protein), beta polypeptide 3 guanine nucleotide binding protein, beta 3 guanine nucleotide-binding protein, beta-3 subunit transducin beta chain 3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q42
Summary	G-protein beta subunit expressed primarily in heart and also in brain [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_021858.3	NP_068630.1	guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
XM_006237383.2	XP_006237445.1	guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	gnb3a	NP_001002437.1
Pan troglodytes (chimpanzee)	GNB3	XP_003313511.1
Macaca mulatta (Rhesus monkey)	GNB3	XP_001110494.1
Rattus norvegicus (Norway rat)	Gnb3	NP_068630.1
Xenopus tropicalis (tropical clawed frog)	gnb3	NP_001011107.1
Homo sapiens (human)	GNB3	NP_002066.1
Canis lupus familiaris (dog)	GNB3	NP_001003004.1
Bos taurus (cattle)	GNB3	NP_001179276.1
Mus musculus (house mouse)	Gnb3	NP_038558.1
Gallus gallus (chicken)	GNB3	XP_004938175.1

Gene Ontology
Bibliography

Related articles in PubMed

GNB3 overexpression causes obesity and metabolic syndrome.
Ozdemir AC, Wynn GM, Vester A, Weitzmann MN, Neigh GN, Srinivasan S, Rudd MK
PloS one12(12)e0188763(2017)

The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route.
Papal S, Cortese M, Legendre K, Sorusch N, Dragavon J, Sahly I, Shorte S, Wolfrum U, Petit C, El-Amraoui A
Human molecular genetics22(18)3773-88(2013 Sep)

Photoreceptor signaling: supporting vision across a wide range of light intensities.
Arshavsky VY, Burns ME
The Journal of biological chemistry287(3)1620-6(2012 Jan)

The cationic region of Rhes mediates its interactions with specific Gbeta subunits.
Hill C, Goddard A, Ladds G, Davey J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology23(1-3)1-8(2009)

Salt consumption-dependent association of the GNB3 gene polymorphism with type 2 DM.
Daimon M, Sato H, Sasaki S, Toriyama S, Emi M, Muramatsu M, Hunt SC, Hopkins PN, Karasawa S, Wada K, Jimbu Y, Kameda W, Susa S, Oizumi T, Fukao A, Kubota I, Kawata S, Kato T
Biochemical and biophysical research communications374(3)576-80(2008 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Gnb3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gnb3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05305	NM_021858.3 Latest version!	Rattus norvegicus G protein subunit beta 3 (Gnb3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa27778	XM_006237383.2 Latest version!	Rattus norvegicus G protein subunit beta 3 (Gnb3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gnb3 ( NM_021858.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_068630.1 Rattus norvegicus G protein subunit beta 3 (Gnb3), mRNA.

Price & Availability↑

CloneID	ORa05305
Clone ID Related Accession (Same CDS sequence)	NM_021858.3
Accession Version	NM_021858.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1023bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569081600000
Organism	Rattus norvegicus(Norway rat)
Product	guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC086422.1. On Aug 31, 2012 this sequence version replaced NM_021858.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC086422.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052297, SAMN00632251 [ECO:0000348] ##Evidence-Data-END##

ATGGGGGAGA TGGAGCAGCT GAAGCAGGAG GCGGAGCAGC TCAAGAAGCA GATTGCTGAT 
GCCAGGAAAG CCTGTGCGGA CATCACTCTG GCTGAGCTTG TGTCTGGCCT GGAGGTGGTG 
GGACGAGTCC AGATGCGGAC ACGGAGGACG TTAAGGGGAC ACCTGGCTAA GATCTATGCC 
ATGCACTGGG CCACTGACTC TAAGCTGCTA GTAAGTGCCT CGCAGGATGG GAAGCTGATC 
GTGTGGGACA CTTACACCAC CAATAAGGTG CATGCTATCC CGCTGCGTTC CTCCTGGGTC 
ATGACCTGTG CCTATGCACC ATCAGGGAAC TTCGTGGCAT GTGGGGGGCT AGATAACATG 
TGCTCAATCT ACAGCCTCAA ATCCCGTGAG GGCAATGTCA AGGTCAGCCG GGAACTCTCG 
GCTCACACAG GTTATCTCTC CTGTTGCCGC TTCCTGGATG ACAACAACAT TGTGACTAGC 
TCTGGGGACA CCACGTGTGC CTTGTGGGAC ATTGAGACGG GGCAGCAGAA GACAGTGTTC 
GTGGGACACA CTGGTGACTG CATGAGCCTG GCTGTGTCCC CAGACTACAA ACTCTTCATC 
TCGGGAGCTT GTGATGCCAG CGCCAAGCTC TGGGATGTGA GGGAAGGGAC CTGTCGCCAG 
ACTTTCACTG GCCACGAGTC AGACATCAAT GCTATCTGTT TCTTTCCCAA TGGGGAGGCC 
ATCTGCACTG GCTCAGATGA TGCCTCCTGC CGCCTCTTTG ACCTGAGGGC AGACCAGGAA 
CTGACAGCCT ACTCCCACGA GAGCATCATC TGTGGCATCA CGTCCGTAGC CTTCTCACTC 
AGTGGTCGCC TGCTCTTTGC TGGCTATGAT GACTTCAACT GCAATGTCTG GGACTCTCTG 
AAGTGTGAGC GTGTAGGCGT TCTTTCTGGC CATGACAACA GAGTCAGTTG CCTGGGGGTC 
ACAGCTGACG GCATGGCTGT GGCCACTGGA TCCTGGGACA GCTTCCTCAA GATCTGGAAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068630.1
CDS	112..1134
Translation	MGEMEQLKQEAEQLKKQIADARKACADITLAELVSGLEVVGRVQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYSLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGVLSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN

Target ORF information:

RefSeq Version	NM_021858.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus G protein subunit beta 3 (Gnb3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021858.3

ORF Insert Sequence:

ATGGGGGAGA TGGAGCAGCT GAAGCAGGAG GCGGAGCAGC TCAAGAAGCA GATTGCTGAT 
GCCAGGAAAG CCTGTGCGGA CATCACTCTG GCTGAGCTTG TGTCTGGCCT GGAGGTGGTG 
GGACGAGTCC AGATGCGGAC ACGGAGGACG TTAAGGGGAC ACCTGGCTAA GATCTATGCC 
ATGCACTGGG CCACTGACTC TAAGCTGCTA GTAAGTGCCT CGCAGGATGG GAAGCTGATC 
GTGTGGGACA CTTACACCAC CAATAAGGTG CATGCTATCC CGCTGCGTTC CTCCTGGGTC 
ATGACCTGTG CCTATGCACC ATCAGGGAAC TTCGTGGCAT GTGGGGGGCT AGATAACATG 
TGCTCAATCT ACAGCCTCAA ATCCCGTGAG GGCAATGTCA AGGTCAGCCG GGAACTCTCG 
GCTCACACAG GTTATCTCTC CTGTTGCCGC TTCCTGGATG ACAACAACAT TGTGACTAGC 
TCTGGGGACA CCACGTGTGC CTTGTGGGAC ATTGAGACGG GGCAGCAGAA GACAGTGTTC 
GTGGGACACA CTGGTGACTG CATGAGCCTG GCTGTGTCCC CAGACTACAA ACTCTTCATC 
TCGGGAGCTT GTGATGCCAG CGCCAAGCTC TGGGATGTGA GGGAAGGGAC CTGTCGCCAG 
ACTTTCACTG GCCACGAGTC AGACATCAAT GCTATCTGTT TCTTTCCCAA TGGGGAGGCC 
ATCTGCACTG GCTCAGATGA TGCCTCCTGC CGCCTCTTTG ACCTGAGGGC AGACCAGGAA 
CTGACAGCCT ACTCCCACGA GAGCATCATC TGTGGCATCA CGTCCGTAGC CTTCTCACTC 
AGTGGTCGCC TGCTCTTTGC TGGCTATGAT GACTTCAACT GCAATGTCTG GGACTCTCTG 
AAGTGTGAGC GTGTAGGCGT TCTTTCTGGC CATGACAACA GAGTCAGTTG CCTGGGGGTC 
ACAGCTGACG GCATGGCTGT GGCCACTGGA TCCTGGGACA GCTTCCTCAA GATCTGGAAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gnb3 ( XM_006237383.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006237445.1 Rattus norvegicus G protein subunit beta 3 (Gnb3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa27778
Clone ID Related Accession (Same CDS sequence)	XM_006237383.2
Accession Version	XM_006237383.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 864bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006237383.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGGAGA TGGAGCAGCT GAAGCAGGAG GCGGAGCAGC TCAAGAAGCA GATTGCTGAT 
GCCAGGAAAG CCTGTGCGGA CATCACTCTG GCTGAGCTTG TGTCTGGCCT GGAGGTGGTG 
GGACGAGTCC AGATGCGGAC ACGGAGGACG TTAAGGGGAC ACCTGGCTAA GATCTATGCC 
ATGCACTGGG CCACTGACTC TAAGCTGCTA GTAAGTGCCT CGCAGGATGG GAAGCTGATC 
GTGTGGGACA CTTACACCAC CAATAAGGTG CATGCTATCC CGCTGCGTTC CTCCTGGGTC 
ATGACCTGTG CCTATGCACC ATCAGGGAAC TTCGTGGCAT GTGGGGGGCT AGATAACATG 
TGCTCAATCT ACAGCCTCAA ATCCCGTGAG GGCAATGTCA AGGTCAGCCG GGAACTCTCG 
GCTCACACAG GTTATCTCTC CTGTTGCCGC TTCCTGGATG ACAACAACAT TGTGACTAGC 
TCTGGGGACA CCACGTGTGC CTTGTGGGAC ATTGAGACGG GGCAGCAGAA GACAGTGTTC 
GTGGGACACA CTGGTGACTG CATGAGCCTG GCTGTGTCCC CAGACTACAA ACTCTTCATC 
TCGGGAGCTT GTGATGCCAG CGCCAAGCTC TGGGATGTGA GGGAAGGGAC CTGTCGCCAG 
ACTTTCACTG GCCACGAGTC AGACATCAAT GCTATCTGTT GCTGGACTCA TGGGTTGAAG 
GAGCTTCAAG AACAACTTCA ATGCAGCTGG CTGCCTCGCC CTACCAAGAA ACAGACCCAG 
AAGCTGAGAG AAGCGGCTCA CACTCCCCCA GTAGGAGCTA GGAAGCAGGC AGGAAGGCAA 
GGCTGTCCCA GGTCTGAGCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006237445.1
CDS	1089..1952
Translation	MGEMEQLKQEAEQLKKQIADARKACADITLAELVSGLEVVGRVQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYSLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICCWTHGLKELQEQLQCSWLPRPTKKQTQKLREAAHTPPVGARKQAGRQGCPRSEP

Target ORF information:

RefSeq Version	XM_006237383.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus G protein subunit beta 3 (Gnb3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006237383.2

ORF Insert Sequence:

ATGGGGGAGA TGGAGCAGCT GAAGCAGGAG GCGGAGCAGC TCAAGAAGCA GATTGCTGAT 
GCCAGGAAAG CCTGTGCGGA CATCACTCTG GCTGAGCTTG TGTCTGGCCT GGAGGTGGTG 
GGACGAGTCC AGATGCGGAC ACGGAGGACG TTAAGGGGAC ACCTGGCTAA GATCTATGCC 
ATGCACTGGG CCACTGACTC TAAGCTGCTA GTAAGTGCCT CGCAGGATGG GAAGCTGATC 
GTGTGGGACA CTTACACCAC CAATAAGGTG CATGCTATCC CGCTGCGTTC CTCCTGGGTC 
ATGACCTGTG CCTATGCACC ATCAGGGAAC TTCGTGGCAT GTGGGGGGCT AGATAACATG 
TGCTCAATCT ACAGCCTCAA ATCCCGTGAG GGCAATGTCA AGGTCAGCCG GGAACTCTCG 
GCTCACACAG GTTATCTCTC CTGTTGCCGC TTCCTGGATG ACAACAACAT TGTGACTAGC 
TCTGGGGACA CCACGTGTGC CTTGTGGGAC ATTGAGACGG GGCAGCAGAA GACAGTGTTC 
GTGGGACACA CTGGTGACTG CATGAGCCTG GCTGTGTCCC CAGACTACAA ACTCTTCATC 
TCGGGAGCTT GTGATGCCAG CGCCAAGCTC TGGGATGTGA GGGAAGGGAC CTGTCGCCAG 
ACTTTCACTG GCCACGAGTC AGACATCAAT GCTATCTGTT GCTGGACTCA TGGGTTGAAG 
GAGCTTCAAG AACAACTTCA ATGCAGCTGG CTGCCTCGCC CTACCAAGAA ACAGACCCAG 
AAGCTGAGAG AAGCGGCTCA CACTCCCCCA GTAGGAGCTA GGAAGCAGGC AGGAAGGCAA 
GGCTGTCCCA GGTCTGAGCC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

GNB3 overexpression causes obesity and metabolic syndrome.
PloS one12(12)e0188763(2017)
Ozdemir AC,Wynn GM,Vester A,Weitzmann MN,Neigh GN,Srinivasan S,Rudd MK

The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route.
Human molecular genetics22(18)3773-88(2013 Sep)
Papal S,Cortese M,Legendre K,Sorusch N,Dragavon J,Sahly I,Shorte S,Wolfrum U,Petit C,El-Amraoui A

Photoreceptor signaling: supporting vision across a wide range of light intensities.
The Journal of biological chemistry287(3)1620-6(2012 Jan)
Arshavsky VY,Burns ME

The cationic region of Rhes mediates its interactions with specific Gbeta subunits.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology23(1-3)1-8(2009)
Hill C,Goddard A,Ladds G,Davey J

Salt consumption-dependent association of the GNB3 gene polymorphism with type 2 DM.
Biochemical and biophysical research communications374(3)576-80(2008 Sep)
Daimon M,Sato H,Sasaki S,Toriyama S,Emi M,Muramatsu M,Hunt SC,Hopkins PN,Karasawa S,Wada K,Jimbu Y,Kameda W,Susa S,Oizumi T,Fukao A,Kubota I,Kawata S,Kato T

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

Gnb3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM