Grk6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Grk6
Entrez Gene ID	59076
Full Name	G protein-coupled receptor kinase 6
Synonyms	Gprk6
General protein information	Preferred Names G protein-coupled receptor kinase 6 Names G protein-coupled receptor kinase 6 g protein-coupled receptor kinase GRK6
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 17 Map Location: 17p14
Summary	G-protein coupled receptor kinase that desensitizes beta adrenergic receptors in myometrium [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001112712.1	NP_001106183.1	G protein-coupled receptor kinase 6 isoform c
XM_008771504.1	XP_008769726.1	G protein-coupled receptor kinase 6 isoform X2
NM_001112713.1	NP_001106184.1	G protein-coupled receptor kinase 6 isoform b
NM_031657.3	NP_113845.2	G protein-coupled receptor kinase 6 isoform a
XM_006253653.3	XP_006253715.1	G protein-coupled receptor kinase 6 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	GRK6	XP_003434543.2
Mus musculus (house mouse)	Grk6	NP_001033107.1
Rattus norvegicus (Norway rat)	Grk6	NP_113845.2
Gallus gallus (chicken)	GRK6	XP_414676.3
Danio rerio (zebrafish)	grk6	XP_689783.2
Xenopus tropicalis (tropical clawed frog)	grk6	XP_002936988.1
Pan troglodytes (chimpanzee)	GRK6	XP_003311032.1
Macaca mulatta (Rhesus monkey)	GRK6	XP_001090003.2
Bos taurus (cattle)	GRK6	NP_001178459.1
Homo sapiens (human)	GRK6	NP_002073.2

Gene Ontology
Bibliography

Related articles in PubMed

Secreted miR-27a Induced by Cyclic Stretch Modulates the Proliferation of Endothelial Cells in Hypertension via GRK6.
Wang L, Bao H, Wang KX, Zhang P, Yao QP, Chen XH, Huang K, Qi YX, Jiang ZL
Scientific reports741058(2017 01)

Overexpression of GRK6 attenuates neuropathic pain via suppression of CXCR2 in rat dorsal root ganglion.
Zhou Y, Li RJ, Li M, Liu X, Zhu HY, Ju Z, Miao X, Xu GY
Molecular pain12(2016)

G protein-coupled receptor kinase 6/β-arrestin 2 system in a rat model of dopamine supersensitivity psychosis.
Oda Y, Tadokoro S, Takase M, Kanahara N, Watanabe H, Shirayama Y, Hashimoto K, Iyo M
Journal of psychopharmacology (Oxford, England)29(12)1308-13(2015 Dec)

Decreased expression and role of GRK6 in spinal cord of rats after chronic constriction injury.
Zhou Y, Huang X, Wu H, Xu Y, Tao T, Xu G, Cheng C, Cao S
Neurochemical research38(10)2168-79(2013 Oct)

GRK-6 mediates FSH action synergistically enhanced by estrogen and the oocyte in rat granulosa cells.
Miyoshi T, Otsuka F, Shimasaki S
Biochemical and biophysical research communications434(2)401-6(2013 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Grk6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Grk6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa43475	XM_008771504.1 Latest version!	Rattus norvegicus G protein-coupled receptor kinase 6 (Grk6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa12600	NM_031657.3 Latest version!	Rattus norvegicus G protein-coupled receptor kinase 6 (Grk6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa12604	NM_001112713.1 Latest version!	Rattus norvegicus G protein-coupled receptor kinase 6 (Grk6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa12614	NM_001112712.1 Latest version!	Rattus norvegicus G protein-coupled receptor kinase 6 (Grk6), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa37707	XM_006253653.3 Latest version!	Rattus norvegicus G protein-coupled receptor kinase 6 (Grk6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Grk6 ( XM_008771504.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008769726.1 Rattus norvegicus G protein-coupled receptor kinase 6 (Grk6), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa43475
Clone ID Related Accession (Same CDS sequence)	XM_008771504.1
Accession Version	XM_008771504.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1308bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	G protein-coupled receptor kinase 6 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005116.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCCCTT TTGCCGACTA CCTCGACAGC ATCTACTTCA ACCGTTTCCT GCAGTGGAAG 
TGGCTGGAAA GGCAGCCAGT GACCAAAAAC ACCTTTAGGC AGTACCGAGT CCTGGGCAAA 
GGTGGCTTTG GGGAGGTGTG TGCCTGCCAG GTGCGGGCAA CAGGCAAGAT GTATGCGTGC 
AAAAAACTGG AAAAGAAACG AATAAAGAAG CGGAAGGGGG AGGCCATGGC TCTCAACGAG 
AAGCAGATCC TGGAGAAAGT GAACAGTAGG TTTGTAGTGA GCTTAGCCTA CGCATATGAG 
ACCAAGGATG CACTGTGCCT GGTGCTGACA TTGATGAATG GAGGCGACCT CAAGTTCCAC 
ATCTACCACA TGGGCCAGGC TGGCTTTCCC GAAGCACGTG CTGTCTTCTA TGCTGCCGAG 
ATCTGCTGTG GTCTGGAGGA CTTACACCGG GAACGCATCG TGTACAGGGA CCTAAAGCCA 
GAGAATATCC TTCTGGATGA CCATGGCCAC ATTCGAATCT CCGACCTGGG CCTGGCTGTG 
CATGTTCCTG AGGGCCAGAC CATCAAAGGC CGTGTGGGCA CTGTGGGCTA CATGGCTCCA 
GAGGTGGTGA AGAATGAGCG CTACACATTC AGTCCTGACT GGTGGGCGCT AGGCTGCCTC 
CTGTACGAGA TGATTGCGGG ACAGTCGCCC TTCCAGCAGA GGAAGAAGAA GATCAAGCGG 
GAGGAGGTGG AGCGGCTGGT CAAGGAGGTG GCTGAGGAGT ACACCGACCG CTTCTCCCCA 
CAGGCACGCT CACTCTGTTC TCAGCTTCTC AACAAGGACC CTGCTGAGCG CCTGGGGTGT 
CGTGGAGGTG GTGCCCGTGA GGTAAAGGAG CACCCCCTTT TCAAGAAACT GAATTTCAAG 
CGGCTGGGAG CTGGAATGCT AGAACCACCT TTTAAACCTG ACCCCCAGGC CATTTACTGC 
AAGGACGTGC TGGACATTGA ACAGTTCTCC ACAGTTAAAG GTGTGGATCT GGAGCCCACA 
GACCAAGACT TCTACCAGAA GTTTGCCACG GGTAGTGTGT CCATCCCCTG GCAGAACGAG 
ATGGTGGAGA CTGAGTGCTT CCAGGAACTA AATGTCTTTG GGCTGGATGG GTCTGTTCCC 
CCAGACCTGG ACTGGAAGGG CCAGCCCACT GCACCCCCCA AGAAGGGATT GCTACAGAGA 
CTCTTCAGTA GACAAAGGAT TGCTGTGGGA ACTGCAGCGA CAGTGAAGAA GAGCTCCCCA 
CCCGCCTCTA GCCCCCAGGC CGAGGCCCCC ACCGGCGGCT GGCGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008769726.1
CDS	738..2045
Translation	MAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVAEEYTDRFSPQARSLCSQLLNKDPAERLGCRGGGAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFSTVKGVDLEPTDQDFYQKFATGSVSIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPTAPPKKGLLQRLFSRQRIAVGTAATVKKSSPPASSPQAEAPTGGWR

Target ORF information:

RefSeq Version	XM_008771504.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus G protein-coupled receptor kinase 6 (Grk6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008771504.1

ORF Insert Sequence:

ATGGCCCCTT TTGCCGACTA CCTCGACAGC ATCTACTTCA ACCGTTTCCT GCAGTGGAAG 
TGGCTGGAAA GGCAGCCAGT GACCAAAAAC ACCTTTAGGC AGTACCGAGT CCTGGGCAAA 
GGTGGCTTTG GGGAGGTGTG TGCCTGCCAG GTGCGGGCAA CAGGCAAGAT GTATGCGTGC 
AAAAAACTGG AAAAGAAACG AATAAAGAAG CGGAAGGGGG AGGCCATGGC TCTCAACGAG 
AAGCAGATCC TGGAGAAAGT GAACAGTAGG TTTGTAGTGA GCTTAGCCTA CGCATATGAG 
ACCAAGGATG CACTGTGCCT GGTGCTGACA TTGATGAATG GAGGCGACCT CAAGTTCCAC 
ATCTACCACA TGGGCCAGGC TGGCTTTCCC GAAGCACGTG CTGTCTTCTA TGCTGCCGAG 
ATCTGCTGTG GTCTGGAGGA CTTACACCGG GAACGCATCG TGTACAGGGA CCTAAAGCCA 
GAGAATATCC TTCTGGATGA CCATGGCCAC ATTCGAATCT CCGACCTGGG CCTGGCTGTG 
CATGTTCCTG AGGGCCAGAC CATCAAAGGC CGTGTGGGCA CTGTGGGCTA CATGGCTCCA 
GAGGTGGTGA AGAATGAGCG CTACACATTC AGTCCTGACT GGTGGGCGCT AGGCTGCCTC 
CTGTACGAGA TGATTGCGGG ACAGTCGCCC TTCCAGCAGA GGAAGAAGAA GATCAAGCGG 
GAGGAGGTGG AGCGGCTGGT CAAGGAGGTG GCTGAGGAGT ACACCGACCG CTTCTCCCCA 
CAGGCACGCT CACTCTGTTC TCAGCTTCTC AACAAGGACC CTGCTGAGCG CCTGGGGTGT 
CGTGGAGGTG GTGCCCGTGA GGTAAAGGAG CACCCCCTTT TCAAGAAACT GAATTTCAAG 
CGGCTGGGAG CTGGAATGCT AGAACCACCT TTTAAACCTG ACCCCCAGGC CATTTACTGC 
AAGGACGTGC TGGACATTGA ACAGTTCTCC ACAGTTAAAG GTGTGGATCT GGAGCCCACA 
GACCAAGACT TCTACCAGAA GTTTGCCACG GGTAGTGTGT CCATCCCCTG GCAGAACGAG 
ATGGTGGAGA CTGAGTGCTT CCAGGAACTA AATGTCTTTG GGCTGGATGG GTCTGTTCCC 
CCAGACCTGG ACTGGAAGGG CCAGCCCACT GCACCCCCCA AGAAGGGATT GCTACAGAGA 
CTCTTCAGTA GACAAAGGAT TGCTGTGGGA ACTGCAGCGA CAGTGAAGAA GAGCTCCCCA 
CCCGCCTCTA GCCCCCAGGC CGAGGCCCCC ACCGGCGGCT GGCGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Grk6 ( NM_031657.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_113845.2 Rattus norvegicus G protein-coupled receptor kinase 6 (Grk6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa12600
Clone ID Related Accession (Same CDS sequence)	NM_031657.3
Accession Version	NM_031657.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1770bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570636800000
Organism	Rattus norvegicus(Norway rat)
Product	G protein-coupled receptor kinase 6 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from X97440.1, EX488847.1 and BQ205012.1. On Dec 19, 2007 this sequence version replaced NM_031657.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X97440.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGAGCTCG AGAACATCGT AGCGAACACG GTGCTACTCA AGGCCCGGGA AGGTGGTGGC 
GGGAATCGTA AAGGCAAGAG CAAGAAATGG CGCCAGATGC TGCAGTTCCC CCACATCAGC 
CAGTGTGAAG AGCTCCGGCT CAGCCTTGAA CGTGACTACC ACAGCCTGTG TGAGCGTCAG 
CCCATTGGGC GCCTGTTATT TCGTGAGTTC TGCGCTACGA GGCCTGAGCT GACCCGCTGT 
ACTGCCTTCC TGGATGGGGT GGCTGAGTAT GAGGTGACCC CTGATGAGAA ACGGAAGGCA 
TGTGGGCGTC GGCTAATGCA GAATTTTCTG AGCCACACGG GTCCTGACCT CATCCCTGAA 
GTTCCCCGGC AGCTGGTGAG TAACTGTGCC CAGCGGCTAG AGCAGGGACC CTGCAAAGAC 
CTCTTCCAGG AGCTGACCCG GCTGACCCAT GAGTACCTAA GCATGGCCCC TTTTGCCGAC 
TACCTCGACA GCATCTACTT CAACCGTTTC CTGCAGTGGA AGTGGCTGGA AAGGCAGCCA 
GTGACCAAAA ACACCTTTAG GCAGTACCGA GTCCTGGGCA AAGGTGGCTT TGGGGAGGTG 
TGTGCCTGCC AGGTGCGGGC AACAGGCAAG ATGTATGCGT GCAAAAAACT GGAAAAGAAA 
CGAATAAAGA AGCGGAAGGG GGAGGCCATG GCTCTCAACG AGAAGCAGAT CCTGGAGAAA 
GTGAACAGTA GGTTTGTAGT GAGCTTAGCC TACGCATATG AGACCAAGGA TGCACTGTGC 
CTGGTGCTGA CATTGATGAA TGGAGGCGAC CTCAAGTTCC ACATCTACCA CATGGGCCAG 
GCTGGCTTTC CCGAAGCACG TGCTGTCTTC TATGCTGCCG AGATCTGCTG TGGTCTGGAG 
GACTTACACC GGGAACGCAT CGTGTACAGG GACCTAAAGC CAGAGAATAT CCTTCTGGAT 
GACCATGGCC ACATTCGAAT CTCCGACCTG GGCCTGGCTG TGCATGTTCC TGAGGGCCAG 
ACCATCAAAG GCCGTGTGGG CACTGTGGGC TACATGGCTC CAGAGGTGGT GAAGAATGAG 
CGCTACACAT TCAGTCCTGA CTGGTGGGCG CTAGGCTGCC TCCTGTACGA GATGATTGCG 
GGACAGTCGC CCTTCCAGCA GAGGAAGAAG AAGATCAAGC GGGAGGAGGT GGAGCGGCTG 
GTCAAGGAGG TGGCTGAGGA GTACACCGAC CGCTTCTCCC CACAGGCACG CTCACTCTGT 
TCTCAGCTTC TCAACAAGGA CCCTGCTGAG CGCCTGGGGT GTCGTGGAGG TGGTGCCCGT 
GAGGTAAAGG AGCACCCCCT TTTCAAGAAA CTGAATTTCA AGCGGCTGGG AGCTGGAATG 
CTAGAACCAC CTTTTAAACC TGACCCCCAG GCCATTTACT GCAAGGACGT GCTGGACATT 
GAACAGTTCT CCACAGTTAA AGGTGTGGAT CTGGAGCCCA CAGACCAAGA CTTCTACCAG 
AAGTTTGCCA CGGGTAGTGT GTCCATCCCC TGGCAGAACG AGATGGTGGA GACTGAGTGC 
TTCCAGGAAC TAAATGTCTT TGGGCTGGAT GGGTCTGTTC CCCCAGACCT GGACTGGAAG 
GGCCAGCCCA CTGCACCCCC CAAGAAGGGA TTGCTACAGA GACTCTTCAG TAGACAAAGG 
ATTGCTGTGG GAACTGCAGC GACAGTGAAG AAGAGCTCCC CACCCGCCTC TAGCCCCCAG 
GCCGAGGCCC CCACCGGCGG CTGGCGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113845.2
CDS	9..1778
Translation	MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQPIGRLLFREFCATRPELTRCTAFLDGVAEYEVTPDEKRKACGRRLMQNFLSHTGPDLIPEVPRQLVSNCAQRLEQGPCKDLFQELTRLTHEYLSMAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVAEEYTDRFSPQARSLCSQLLNKDPAERLGCRGGGAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFSTVKGVDLEPTDQDFYQKFATGSVSIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPTAPPKKGLLQRLFSRQRIAVGTAATVKKSSPPASSPQAEAPTGGWR

Target ORF information:

RefSeq Version	NM_031657.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus G protein-coupled receptor kinase 6 (Grk6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031657.3

ORF Insert Sequence:

ATGGAGCTCG AGAACATCGT AGCGAACACG GTGCTACTCA AGGCCCGGGA AGGTGGTGGC 
GGGAATCGTA AAGGCAAGAG CAAGAAATGG CGCCAGATGC TGCAGTTCCC CCACATCAGC 
CAGTGTGAAG AGCTCCGGCT CAGCCTTGAA CGTGACTACC ACAGCCTGTG TGAGCGTCAG 
CCCATTGGGC GCCTGTTATT TCGTGAGTTC TGCGCTACGA GGCCTGAGCT GACCCGCTGT 
ACTGCCTTCC TGGATGGGGT GGCTGAGTAT GAGGTGACCC CTGATGAGAA ACGGAAGGCA 
TGTGGGCGTC GGCTAATGCA GAATTTTCTG AGCCACACGG GTCCTGACCT CATCCCTGAA 
GTTCCCCGGC AGCTGGTGAG TAACTGTGCC CAGCGGCTAG AGCAGGGACC CTGCAAAGAC 
CTCTTCCAGG AGCTGACCCG GCTGACCCAT GAGTACCTAA GCATGGCCCC TTTTGCCGAC 
TACCTCGACA GCATCTACTT CAACCGTTTC CTGCAGTGGA AGTGGCTGGA AAGGCAGCCA 
GTGACCAAAA ACACCTTTAG GCAGTACCGA GTCCTGGGCA AAGGTGGCTT TGGGGAGGTG 
TGTGCCTGCC AGGTGCGGGC AACAGGCAAG ATGTATGCGT GCAAAAAACT GGAAAAGAAA 
CGAATAAAGA AGCGGAAGGG GGAGGCCATG GCTCTCAACG AGAAGCAGAT CCTGGAGAAA 
GTGAACAGTA GGTTTGTAGT GAGCTTAGCC TACGCATATG AGACCAAGGA TGCACTGTGC 
CTGGTGCTGA CATTGATGAA TGGAGGCGAC CTCAAGTTCC ACATCTACCA CATGGGCCAG 
GCTGGCTTTC CCGAAGCACG TGCTGTCTTC TATGCTGCCG AGATCTGCTG TGGTCTGGAG 
GACTTACACC GGGAACGCAT CGTGTACAGG GACCTAAAGC CAGAGAATAT CCTTCTGGAT 
GACCATGGCC ACATTCGAAT CTCCGACCTG GGCCTGGCTG TGCATGTTCC TGAGGGCCAG 
ACCATCAAAG GCCGTGTGGG CACTGTGGGC TACATGGCTC CAGAGGTGGT GAAGAATGAG 
CGCTACACAT TCAGTCCTGA CTGGTGGGCG CTAGGCTGCC TCCTGTACGA GATGATTGCG 
GGACAGTCGC CCTTCCAGCA GAGGAAGAAG AAGATCAAGC GGGAGGAGGT GGAGCGGCTG 
GTCAAGGAGG TGGCTGAGGA GTACACCGAC CGCTTCTCCC CACAGGCACG CTCACTCTGT 
TCTCAGCTTC TCAACAAGGA CCCTGCTGAG CGCCTGGGGT GTCGTGGAGG TGGTGCCCGT 
GAGGTAAAGG AGCACCCCCT TTTCAAGAAA CTGAATTTCA AGCGGCTGGG AGCTGGAATG 
CTAGAACCAC CTTTTAAACC TGACCCCCAG GCCATTTACT GCAAGGACGT GCTGGACATT 
GAACAGTTCT CCACAGTTAA AGGTGTGGAT CTGGAGCCCA CAGACCAAGA CTTCTACCAG 
AAGTTTGCCA CGGGTAGTGT GTCCATCCCC TGGCAGAACG AGATGGTGGA GACTGAGTGC 
TTCCAGGAAC TAAATGTCTT TGGGCTGGAT GGGTCTGTTC CCCCAGACCT GGACTGGAAG 
GGCCAGCCCA CTGCACCCCC CAAGAAGGGA TTGCTACAGA GACTCTTCAG TAGACAAAGG 
ATTGCTGTGG GAACTGCAGC GACAGTGAAG AAGAGCTCCC CACCCGCCTC TAGCCCCCAG 
GCCGAGGCCC CCACCGGCGG CTGGCGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Grk6 ( NM_001112713.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001106184.1 Rattus norvegicus G protein-coupled receptor kinase 6 (Grk6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ORa12604
Clone ID Related Accession (Same CDS sequence)	NM_001112713.1
Accession Version	NM_001112713.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1683bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570636800000
Organism	Rattus norvegicus(Norway rat)
Product	G protein-coupled receptor kinase 6 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF040750.1 and EX488847.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF040750.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGAGCTCG AGAACATCGT AGCGAACACG GTGCTACTCA AGGCCCGGGA AGGTGGTGGC 
GGGAATCGTA AAGGCAAGAG CAAGAAATGG CGCCAGATGC TGCAGTTCCC CCACATCAGC 
CAGTGTGAAG AGCTCCGGCT CAGCCTTGAA CGTGACTACC ACAGCCTGTG TGAGCGTCAG 
CCCATTGGGC GCCTGTTATT TCGTGAGTTC TGCGCTACGA GGCCTGAGCT GACCCGCTGT 
ACTGCCTTCC TGGATGGGGT GGCTGAGTAT GAGGTGACCC CTGATGAGAA ACGGAAGGCA 
TGTGGGCGTC GGCTAATGCA GAATTTTCTG AGCCACACGG GTCCTGACCT CATCCCTGAA 
GTTCCCCGGC AGCTGGTGAG TAACTGTGCC CAGCGGCTAG AGCAGGGACC CTGCAAAGAC 
CTCTTCCAGG AGCTGACCCG GCTGACCCAT GAGTACCTAA GCATGGCCCC TTTTGCCGAC 
TACCTCGACA GCATCTACTT CAACCGTTTC CTGCAGTGGA AGTGGCTGGA AAGGCAGCCA 
GTGACCAAAA ACACCTTTAG GCAGTACCGA GTCCTGGGCA AAGGTGGCTT TGGGGAGGTG 
TGTGCCTGCC AGGTGCGGGC AACAGGCAAG ATGTATGCGT GCAAAAAACT GGAAAAGAAA 
CGAATAAAGA AGCGGAAGGG GGAGGCCATG GCTCTCAACG AGAAGCAGAT CCTGGAGAAA 
GTGAACAGTA GGTTTGTAGT GAGCTTAGCC TACGCATATG AGACCAAGGA TGCACTGTGC 
CTGGTGCTGA CATTGATGAA TGGAGGCGAC CTCAAGTTCC ACATCTACCA CATGGGCCAG 
GCTGGCTTTC CCGAAGCACG TGCTGTCTTC TATGCTGCCG AGATCTGCTG TGGTCTGGAG 
GACTTACACC GGGAACGCAT CGTGTACAGG GACCTAAAGC CAGAGAATAT CCTTCTGGAT 
GACCATGGCC ACATTCGAAT CTCCGACCTG GGCCTGGCTG TGCATGTTCC TGAGGGCCAG 
ACCATCAAAG GCCGTGTGGG CACTGTGGGC TACATGGCTC CAGAGGTGGT GAAGAATGAG 
CGCTACACAT TCAGTCCTGA CTGGTGGGCG CTAGGCTGCC TCCTGTACGA GATGATTGCG 
GGACAGTCGC CCTTCCAGCA GAGGAAGAAG AAGATCAAGC GGGAGGAGGT GGAGCGGCTG 
GTCAAGGAGG TGGCTGAGGA GTACACCGAC CGCTTCTCCC CACAGGCACG CTCACTCTGT 
TCTCAGCTTC TCAACAAGGA CCCTGCTGAG CGCCTGGGGT GTCGTGGAGG TGGTGCCCGT 
GAGGTAAAGG AGCACCCCCT TTTCAAGAAA CTGAATTTCA AGCGGCTGGG AGCTGGAATG 
CTAGAACCAC CTTTTAAACC TGACCCCCAG GCCATTTACT GCAAGGACGT GCTGGACATT 
GAACAGTTCT CCACAGTTAA AGGTGTGGAT CTGGAGCCCA CAGACCAAGA CTTCTACCAG 
AAGTTTGCCA CGGGTAGTGT GTCCATCCCC TGGCAGAACG AGATGGTGGA GACTGAGTGC 
TTCCAGGAAC TAAATGTCTT TGGGCTGGAT GGGTCTGTTC CCCCAGACCT GGACTGGAAG 
GGCCAGCCCA CTGCACCCCC CAAGAAGGGA TTGCTACAGA GACTCTTCAG TAGACAAAGG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001106184.1
CDS	9..1691
Translation	MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQPIGRLLFREFCATRPELTRCTAFLDGVAEYEVTPDEKRKACGRRLMQNFLSHTGPDLIPEVPRQLVSNCAQRLEQGPCKDLFQELTRLTHEYLSMAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVAEEYTDRFSPQARSLCSQLLNKDPAERLGCRGGGAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFSTVKGVDLEPTDQDFYQKFATGSVSIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPTAPPKKGLLQRLFSRQR

Target ORF information:

RefSeq Version	NM_001112713.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus G protein-coupled receptor kinase 6 (Grk6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001112713.1

ORF Insert Sequence:

ATGGAGCTCG AGAACATCGT AGCGAACACG GTGCTACTCA AGGCCCGGGA AGGTGGTGGC 
GGGAATCGTA AAGGCAAGAG CAAGAAATGG CGCCAGATGC TGCAGTTCCC CCACATCAGC 
CAGTGTGAAG AGCTCCGGCT CAGCCTTGAA CGTGACTACC ACAGCCTGTG TGAGCGTCAG 
CCCATTGGGC GCCTGTTATT TCGTGAGTTC TGCGCTACGA GGCCTGAGCT GACCCGCTGT 
ACTGCCTTCC TGGATGGGGT GGCTGAGTAT GAGGTGACCC CTGATGAGAA ACGGAAGGCA 
TGTGGGCGTC GGCTAATGCA GAATTTTCTG AGCCACACGG GTCCTGACCT CATCCCTGAA 
GTTCCCCGGC AGCTGGTGAG TAACTGTGCC CAGCGGCTAG AGCAGGGACC CTGCAAAGAC 
CTCTTCCAGG AGCTGACCCG GCTGACCCAT GAGTACCTAA GCATGGCCCC TTTTGCCGAC 
TACCTCGACA GCATCTACTT CAACCGTTTC CTGCAGTGGA AGTGGCTGGA AAGGCAGCCA 
GTGACCAAAA ACACCTTTAG GCAGTACCGA GTCCTGGGCA AAGGTGGCTT TGGGGAGGTG 
TGTGCCTGCC AGGTGCGGGC AACAGGCAAG ATGTATGCGT GCAAAAAACT GGAAAAGAAA 
CGAATAAAGA AGCGGAAGGG GGAGGCCATG GCTCTCAACG AGAAGCAGAT CCTGGAGAAA 
GTGAACAGTA GGTTTGTAGT GAGCTTAGCC TACGCATATG AGACCAAGGA TGCACTGTGC 
CTGGTGCTGA CATTGATGAA TGGAGGCGAC CTCAAGTTCC ACATCTACCA CATGGGCCAG 
GCTGGCTTTC CCGAAGCACG TGCTGTCTTC TATGCTGCCG AGATCTGCTG TGGTCTGGAG 
GACTTACACC GGGAACGCAT CGTGTACAGG GACCTAAAGC CAGAGAATAT CCTTCTGGAT 
GACCATGGCC ACATTCGAAT CTCCGACCTG GGCCTGGCTG TGCATGTTCC TGAGGGCCAG 
ACCATCAAAG GCCGTGTGGG CACTGTGGGC TACATGGCTC CAGAGGTGGT GAAGAATGAG 
CGCTACACAT TCAGTCCTGA CTGGTGGGCG CTAGGCTGCC TCCTGTACGA GATGATTGCG 
GGACAGTCGC CCTTCCAGCA GAGGAAGAAG AAGATCAAGC GGGAGGAGGT GGAGCGGCTG 
GTCAAGGAGG TGGCTGAGGA GTACACCGAC CGCTTCTCCC CACAGGCACG CTCACTCTGT 
TCTCAGCTTC TCAACAAGGA CCCTGCTGAG CGCCTGGGGT GTCGTGGAGG TGGTGCCCGT 
GAGGTAAAGG AGCACCCCCT TTTCAAGAAA CTGAATTTCA AGCGGCTGGG AGCTGGAATG 
CTAGAACCAC CTTTTAAACC TGACCCCCAG GCCATTTACT GCAAGGACGT GCTGGACATT 
GAACAGTTCT CCACAGTTAA AGGTGTGGAT CTGGAGCCCA CAGACCAAGA CTTCTACCAG 
AAGTTTGCCA CGGGTAGTGT GTCCATCCCC TGGCAGAACG AGATGGTGGA GACTGAGTGC 
TTCCAGGAAC TAAATGTCTT TGGGCTGGAT GGGTCTGTTC CCCCAGACCT GGACTGGAAG 
GGCCAGCCCA CTGCACCCCC CAAGAAGGGA TTGCTACAGA GACTCTTCAG TAGACAAAGG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Grk6 ( NM_001112712.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001106183.1 Rattus norvegicus G protein-coupled receptor kinase 6 (Grk6), transcript variant 3, mRNA.

Price & Availability↑

CloneID	ORa12614
Clone ID Related Accession (Same CDS sequence)	NM_001112712.1
Accession Version	NM_001112712.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1731bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570636800000
Organism	Rattus norvegicus(Norway rat)
Product	G protein-coupled receptor kinase 6 isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from X97439.1, EX488847.1 and BQ205012.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X97439.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGAGCTCG AGAACATCGT AGCGAACACG GTGCTACTCA AGGCCCGGGA AGGTGGTGGC 
GGGAATCGTA AAGGCAAGAG CAAGAAATGG CGCCAGATGC TGCAGTTCCC CCACATCAGC 
CAGTGTGAAG AGCTCCGGCT CAGCCTTGAA CGTGACTACC ACAGCCTGTG TGAGCGTCAG 
CCCATTGGGC GCCTGTTATT TCGTGAGTTC TGCGCTACGA GGCCTGAGCT GACCCGCTGT 
ACTGCCTTCC TGGATGGGGT GGCTGAGTAT GAGGTGACCC CTGATGAGAA ACGGAAGGCA 
TGTGGGCGTC GGCTAATGCA GAATTTTCTG AGCCACACGG GTCCTGACCT CATCCCTGAA 
GTTCCCCGGC AGCTGGTGAG TAACTGTGCC CAGCGGCTAG AGCAGGGACC CTGCAAAGAC 
CTCTTCCAGG AGCTGACCCG GCTGACCCAT GAGTACCTAA GCATGGCCCC TTTTGCCGAC 
TACCTCGACA GCATCTACTT CAACCGTTTC CTGCAGTGGA AGTGGCTGGA AAGGCAGCCA 
GTGACCAAAA ACACCTTTAG GCAGTACCGA GTCCTGGGCA AAGGTGGCTT TGGGGAGGTG 
TGTGCCTGCC AGGTGCGGGC AACAGGCAAG ATGTATGCGT GCAAAAAACT GGAAAAGAAA 
CGAATAAAGA AGCGGAAGGG GGAGGCCATG GCTCTCAACG AGAAGCAGAT CCTGGAGAAA 
GTGAACAGTA GGTTTGTAGT GAGCTTAGCC TACGCATATG AGACCAAGGA TGCACTGTGC 
CTGGTGCTGA CATTGATGAA TGGAGGCGAC CTCAAGTTCC ACATCTACCA CATGGGCCAG 
GCTGGCTTTC CCGAAGCACG TGCTGTCTTC TATGCTGCCG AGATCTGCTG TGGTCTGGAG 
GACTTACACC GGGAACGCAT CGTGTACAGG GACCTAAAGC CAGAGAATAT CCTTCTGGAT 
GACCATGGCC ACATTCGAAT CTCCGACCTG GGCCTGGCTG TGCATGTTCC TGAGGGCCAG 
ACCATCAAAG GCCGTGTGGG CACTGTGGGC TACATGGCTC CAGAGGTGGT GAAGAATGAG 
CGCTACACAT TCAGTCCTGA CTGGTGGGCG CTAGGCTGCC TCCTGTACGA GATGATTGCG 
GGACAGTCGC CCTTCCAGCA GAGGAAGAAG AAGATCAAGC GGGAGGAGGT GGAGCGGCTG 
GTCAAGGAGG TGGCTGAGGA GTACACCGAC CGCTTCTCCC CACAGGCACG CTCACTCTGT 
TCTCAGCTTC TCAACAAGGA CCCTGCTGAG CGCCTGGGGT GTCGTGGAGG TGGTGCCCGT 
GAGGTAAAGG AGCACCCCCT TTTCAAGAAA CTGAATTTCA AGCGGCTGGG AGCTGGAATG 
CTAGAACCAC CTTTTAAACC TGACCCCCAG GCCATTTACT GCAAGGACGT GCTGGACATT 
GAACAGTTCT CCACAGTTAA AGGTGTGGAT CTGGAGCCCA CAGACCAAGA CTTCTACCAG 
AAGTTTGCCA CGGGTAGTGT GTCCATCCCC TGGCAGAACG AGATGGTGGA GACTGAGTGC 
TTCCAGGAAC TAAATGTCTT TGGGCTGGAT GGGTCTGTTC CCCCAGACCT GGACTGGAAG 
GGCCAGCCCA CTGCACCCCC CAAGAAGGGA TTGCTACAGA GACTCTTCAG TAGACAAGAT 
TGCTGTGGGA ACTGCAGCGA CAGTGAAGAA GAGCTCCCCA CCCGCCTCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001106183.1
CDS	9..1739
Translation	MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQPIGRLLFREFCATRPELTRCTAFLDGVAEYEVTPDEKRKACGRRLMQNFLSHTGPDLIPEVPRQLVSNCAQRLEQGPCKDLFQELTRLTHEYLSMAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVAEEYTDRFSPQARSLCSQLLNKDPAERLGCRGGGAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFSTVKGVDLEPTDQDFYQKFATGSVSIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPTAPPKKGLLQRLFSRQDCCGNCSDSEEELPTRL

Target ORF information:

RefSeq Version	NM_001112712.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus G protein-coupled receptor kinase 6 (Grk6), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001112712.1

ORF Insert Sequence:

ATGGAGCTCG AGAACATCGT AGCGAACACG GTGCTACTCA AGGCCCGGGA AGGTGGTGGC 
GGGAATCGTA AAGGCAAGAG CAAGAAATGG CGCCAGATGC TGCAGTTCCC CCACATCAGC 
CAGTGTGAAG AGCTCCGGCT CAGCCTTGAA CGTGACTACC ACAGCCTGTG TGAGCGTCAG 
CCCATTGGGC GCCTGTTATT TCGTGAGTTC TGCGCTACGA GGCCTGAGCT GACCCGCTGT 
ACTGCCTTCC TGGATGGGGT GGCTGAGTAT GAGGTGACCC CTGATGAGAA ACGGAAGGCA 
TGTGGGCGTC GGCTAATGCA GAATTTTCTG AGCCACACGG GTCCTGACCT CATCCCTGAA 
GTTCCCCGGC AGCTGGTGAG TAACTGTGCC CAGCGGCTAG AGCAGGGACC CTGCAAAGAC 
CTCTTCCAGG AGCTGACCCG GCTGACCCAT GAGTACCTAA GCATGGCCCC TTTTGCCGAC 
TACCTCGACA GCATCTACTT CAACCGTTTC CTGCAGTGGA AGTGGCTGGA AAGGCAGCCA 
GTGACCAAAA ACACCTTTAG GCAGTACCGA GTCCTGGGCA AAGGTGGCTT TGGGGAGGTG 
TGTGCCTGCC AGGTGCGGGC AACAGGCAAG ATGTATGCGT GCAAAAAACT GGAAAAGAAA 
CGAATAAAGA AGCGGAAGGG GGAGGCCATG GCTCTCAACG AGAAGCAGAT CCTGGAGAAA 
GTGAACAGTA GGTTTGTAGT GAGCTTAGCC TACGCATATG AGACCAAGGA TGCACTGTGC 
CTGGTGCTGA CATTGATGAA TGGAGGCGAC CTCAAGTTCC ACATCTACCA CATGGGCCAG 
GCTGGCTTTC CCGAAGCACG TGCTGTCTTC TATGCTGCCG AGATCTGCTG TGGTCTGGAG 
GACTTACACC GGGAACGCAT CGTGTACAGG GACCTAAAGC CAGAGAATAT CCTTCTGGAT 
GACCATGGCC ACATTCGAAT CTCCGACCTG GGCCTGGCTG TGCATGTTCC TGAGGGCCAG 
ACCATCAAAG GCCGTGTGGG CACTGTGGGC TACATGGCTC CAGAGGTGGT GAAGAATGAG 
CGCTACACAT TCAGTCCTGA CTGGTGGGCG CTAGGCTGCC TCCTGTACGA GATGATTGCG 
GGACAGTCGC CCTTCCAGCA GAGGAAGAAG AAGATCAAGC GGGAGGAGGT GGAGCGGCTG 
GTCAAGGAGG TGGCTGAGGA GTACACCGAC CGCTTCTCCC CACAGGCACG CTCACTCTGT 
TCTCAGCTTC TCAACAAGGA CCCTGCTGAG CGCCTGGGGT GTCGTGGAGG TGGTGCCCGT 
GAGGTAAAGG AGCACCCCCT TTTCAAGAAA CTGAATTTCA AGCGGCTGGG AGCTGGAATG 
CTAGAACCAC CTTTTAAACC TGACCCCCAG GCCATTTACT GCAAGGACGT GCTGGACATT 
GAACAGTTCT CCACAGTTAA AGGTGTGGAT CTGGAGCCCA CAGACCAAGA CTTCTACCAG 
AAGTTTGCCA CGGGTAGTGT GTCCATCCCC TGGCAGAACG AGATGGTGGA GACTGAGTGC 
TTCCAGGAAC TAAATGTCTT TGGGCTGGAT GGGTCTGTTC CCCCAGACCT GGACTGGAAG 
GGCCAGCCCA CTGCACCCCC CAAGAAGGGA TTGCTACAGA GACTCTTCAG TAGACAAGAT 
TGCTGTGGGA ACTGCAGCGA CAGTGAAGAA GAGCTCCCCA CCCGCCTCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Grk6 ( XM_006253653.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006253715.1 Rattus norvegicus G protein-coupled receptor kinase 6 (Grk6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa37707
Clone ID Related Accession (Same CDS sequence)	XM_006253653.3
Accession Version	XM_006253653.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1674bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	G protein-coupled receptor kinase 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005116.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006253653.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGCAGT TCCCCCACAT CAGCCAGTGT GAAGAGCTCC GGCTCAGCCT TGAACGTGAC 
TACCACAGCC TGTGTGAGCG TCAGCCCATT GGGCGCCTGT TATTTCGTGA GTTCTGCGCT 
ACGAGGCCTG AGCTGACCCG CTGTACTGCC TTCCTGGATG GGGTGGCTGA GTATGAGGTG 
ACCCCTGATG AGAAACGGAA GGCATGTGGG CGTCGGCTAA TGCAGAATTT TCTGAGCCAC 
ACGGGTCCTG ACCTCATCCC TGAAGTTCCC CGGCAGCTGG TGAGTAACTG TGCCCAGCGG 
CTAGAGCAGG GACCCTGCAA AGACCTCTTC CAGGAGCTGA CCCGGCTGAC CCATGAGTAC 
CTAAGCATGG CCCCTTTTGC CGACTACCTC GACAGCATCT ACTTCAACCG TTTCCTGCAG 
TGGAAGTGGC TGGAAAGGCA GCCAGTGACC AAAAACACCT TTAGGCAGTA CCGAGTCCTG 
GGCAAAGGTG GCTTTGGGGA GGTGTGTGCC TGCCAGGTGC GGGCAACAGG CAAGATGTAT 
GCGTGCAAAA AACTGGAAAA GAAACGAATA AAGAAGCGGA AGGGGGAGGC CATGGCTCTC 
AACGAGAAGC AGATCCTGGA GAAAGTGAAC AGTAGGTTTG TAGTGAGCTT AGCCTACGCA 
TATGAGACCA AGGATGCACT GTGCCTGGTG CTGACATTGA TGAATGGAGG CGACCTCAAG 
TTCCACATCT ACCACATGGG CCAGGCTGGC TTTCCCGAAG CACGTGCTGT CTTCTATGCT 
GCCGAGATCT GCTGTGGTCT GGAGGACTTA CACCGGGAAC GCATCGTGTA CAGGGACCTA 
AAGCCAGAGA ATATCCTTCT GGATGACCAT GGCCACATTC GAATCTCCGA CCTGGGCCTG 
GCTGTGCATG TTCCTGAGGG CCAGACCATC AAAGGCCGTG TGGGCACTGT GGGCTACATG 
GCTCCAGAGG TGGTGAAGAA TGAGCGCTAC ACATTCAGTC CTGACTGGTG GGCGCTAGGC 
TGCCTCCTGT ACGAGATGAT TGCGGGACAG TCGCCCTTCC AGCAGAGGAA GAAGAAGATC 
AAGCGGGAGG AGGTGGAGCG GCTGGTCAAG GAGGTGGCTG AGGAGTACAC CGACCGCTTC 
TCCCCACAGG CACGCTCACT CTGTTCTCAG CTTCTCAACA AGGACCCTGC TGAGCGCCTG 
GGGTGTCGTG GAGGTGGTGC CCGTGAGGTA AAGGAGCACC CCCTTTTCAA GAAACTGAAT 
TTCAAGCGGC TGGGAGCTGG AATGCTAGAA CCACCTTTTA AACCTGACCC CCAGGCCATT 
TACTGCAAGG ACGTGCTGGA CATTGAACAG TTCTCCACAG TTAAAGGTGT GGATCTGGAG 
CCCACAGACC AAGACTTCTA CCAGAAGTTT GCCACGGGTA GTGTGTCCAT CCCCTGGCAG 
AACGAGATGG TGGAGACTGA GTGCTTCCAG GAACTAAATG TCTTTGGGCT GGATGGGTCT 
GTTCCCCCAG ACCTGGACTG GAAGGGCCAG CCCACTGCAC CCCCCAAGAA GGGATTGCTA 
CAGAGACTCT TCAGTAGACA AAGGATTGCT GTGGGAACTG CAGCGACAGT GAAGAAGAGC 
TCCCCACCCG CCTCTAGCCC CCAGGCCGAG GCCCCCACCG GCGGCTGGCG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006253715.1
CDS	208..1881
Translation	MLQFPHISQCEELRLSLERDYHSLCERQPIGRLLFREFCATRPELTRCTAFLDGVAEYEVTPDEKRKACGRRLMQNFLSHTGPDLIPEVPRQLVSNCAQRLEQGPCKDLFQELTRLTHEYLSMAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVAEEYTDRFSPQARSLCSQLLNKDPAERLGCRGGGAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFSTVKGVDLEPTDQDFYQKFATGSVSIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPTAPPKKGLLQRLFSRQRIAVGTAATVKKSSPPASSPQAEAPTGGWR

Target ORF information:

RefSeq Version	XM_006253653.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus G protein-coupled receptor kinase 6 (Grk6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006253653.3

ORF Insert Sequence:

ATGCTGCAGT TCCCCCACAT CAGCCAGTGT GAAGAGCTCC GGCTCAGCCT TGAACGTGAC 
TACCACAGCC TGTGTGAGCG TCAGCCCATT GGGCGCCTGT TATTTCGTGA GTTCTGCGCT 
ACGAGGCCTG AGCTGACCCG CTGTACTGCC TTCCTGGATG GGGTGGCTGA GTATGAGGTG 
ACCCCTGATG AGAAACGGAA GGCATGTGGG CGTCGGCTAA TGCAGAATTT TCTGAGCCAC 
ACGGGTCCTG ACCTCATCCC TGAAGTTCCC CGGCAGCTGG TGAGTAACTG TGCCCAGCGG 
CTAGAGCAGG GACCCTGCAA AGACCTCTTC CAGGAGCTGA CCCGGCTGAC CCATGAGTAC 
CTAAGCATGG CCCCTTTTGC CGACTACCTC GACAGCATCT ACTTCAACCG TTTCCTGCAG 
TGGAAGTGGC TGGAAAGGCA GCCAGTGACC AAAAACACCT TTAGGCAGTA CCGAGTCCTG 
GGCAAAGGTG GCTTTGGGGA GGTGTGTGCC TGCCAGGTGC GGGCAACAGG CAAGATGTAT 
GCGTGCAAAA AACTGGAAAA GAAACGAATA AAGAAGCGGA AGGGGGAGGC CATGGCTCTC 
AACGAGAAGC AGATCCTGGA GAAAGTGAAC AGTAGGTTTG TAGTGAGCTT AGCCTACGCA 
TATGAGACCA AGGATGCACT GTGCCTGGTG CTGACATTGA TGAATGGAGG CGACCTCAAG 
TTCCACATCT ACCACATGGG CCAGGCTGGC TTTCCCGAAG CACGTGCTGT CTTCTATGCT 
GCCGAGATCT GCTGTGGTCT GGAGGACTTA CACCGGGAAC GCATCGTGTA CAGGGACCTA 
AAGCCAGAGA ATATCCTTCT GGATGACCAT GGCCACATTC GAATCTCCGA CCTGGGCCTG 
GCTGTGCATG TTCCTGAGGG CCAGACCATC AAAGGCCGTG TGGGCACTGT GGGCTACATG 
GCTCCAGAGG TGGTGAAGAA TGAGCGCTAC ACATTCAGTC CTGACTGGTG GGCGCTAGGC 
TGCCTCCTGT ACGAGATGAT TGCGGGACAG TCGCCCTTCC AGCAGAGGAA GAAGAAGATC 
AAGCGGGAGG AGGTGGAGCG GCTGGTCAAG GAGGTGGCTG AGGAGTACAC CGACCGCTTC 
TCCCCACAGG CACGCTCACT CTGTTCTCAG CTTCTCAACA AGGACCCTGC TGAGCGCCTG 
GGGTGTCGTG GAGGTGGTGC CCGTGAGGTA AAGGAGCACC CCCTTTTCAA GAAACTGAAT 
TTCAAGCGGC TGGGAGCTGG AATGCTAGAA CCACCTTTTA AACCTGACCC CCAGGCCATT 
TACTGCAAGG ACGTGCTGGA CATTGAACAG TTCTCCACAG TTAAAGGTGT GGATCTGGAG 
CCCACAGACC AAGACTTCTA CCAGAAGTTT GCCACGGGTA GTGTGTCCAT CCCCTGGCAG 
AACGAGATGG TGGAGACTGA GTGCTTCCAG GAACTAAATG TCTTTGGGCT GGATGGGTCT 
GTTCCCCCAG ACCTGGACTG GAAGGGCCAG CCCACTGCAC CCCCCAAGAA GGGATTGCTA 
CAGAGACTCT TCAGTAGACA AAGGATTGCT GTGGGAACTG CAGCGACAGT GAAGAAGAGC 
TCCCCACCCG CCTCTAGCCC CCAGGCCGAG GCCCCCACCG GCGGCTGGCG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Secreted miR-27a Induced by Cyclic Stretch Modulates the Proliferation of Endothelial Cells in Hypertension via GRK6.
Scientific reports741058(2017 01)
Wang L,Bao H,Wang KX,Zhang P,Yao QP,Chen XH,Huang K,Qi YX,Jiang ZL

Overexpression of GRK6 attenuates neuropathic pain via suppression of CXCR2 in rat dorsal root ganglion.
Molecular pain12(2016)
Zhou Y,Li RJ,Li M,Liu X,Zhu HY,Ju Z,Miao X,Xu GY

G protein-coupled receptor kinase 6/β-arrestin 2 system in a rat model of dopamine supersensitivity psychosis.
Journal of psychopharmacology (Oxford, England)29(12)1308-13(2015 Dec)
Oda Y,Tadokoro S,Takase M,Kanahara N,Watanabe H,Shirayama Y,Hashimoto K,Iyo M

Decreased expression and role of GRK6 in spinal cord of rats after chronic constriction injury.
Neurochemical research38(10)2168-79(2013 Oct)
Zhou Y,Huang X,Wu H,Xu Y,Tao T,Xu G,Cheng C,Cao S

GRK-6 mediates FSH action synergistically enhanced by estrogen and the oocyte in rat granulosa cells.
Biochemical and biophysical research communications434(2)401-6(2013 May)
Miyoshi T,Otsuka F,Shimasaki S

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

Grk6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM