| Gene Symbol | Lxn |
| Entrez Gene ID | 59073 |
| Full Name | latexin |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | inhibits the proteolytic activity of carboxypeptidase A; may mediate prevention of cytosolic protein degradation [RGD, Feb 2006]. |
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Lxn cDNA ORF clone, Rattus norvegicus(Norway rat)
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Gene
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Clones
gRNAs
The following Lxn gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lxn cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID ORa08395 Clone ID Related Accession (Same CDS sequence) NM_031655.1 Accession Version NM_031655.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 672bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1568908800000 Organism Rattus norvegicus(Norway rat) Product latexin Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X76985.1. ##Evidence-Data-START## Transcript exon combination :: X76985.1, FQ220594.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00632259 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661ATGGAAGAAA TCCCACCCAC CCACTACGCT GCGTCCAGGG CTGCCTCGGT GGCAGAGAAC
TGTATAAATT ATCAGCAAGG GACCCCCAAC AAGGTATTCA AGGTGCAGAC GGTCCAGCAG
GCAAGCAAGG AGGATATCCC AGGAAGAGGC CACAAGTACC ATCTGAAGTT TTCTGTGGAA
GAAATTATCC AAAAACAAGT TACAGTGAGC TGCACGGCTG AAGTTCTTTA CCCTCGAATG
GGACAAGGCT CTGCACCGGA AGTCAACTTC ACATTTGAAG GAGAAATCGG CAAGAACCCA
GATGAGGAAG ACAACACGTT TTATCAAAGA CTCATGTCCA TGAAGGAACC ACTACAAGCA
CAAAATATTC CAGACAATTT TGGAAATGTG TCTCCACAAA TGAAGCCGGT CCACCACTTA
GCCTGGGTCG CCTGTGGTTA TGTAATGTGG CAGAACTCGA CTGAAGACAC ATGGTATAAA
ATGGCAAAGA TTCAAACGGT CAAGCAAGTG CAAAGAAACG ATGACTTCAT TGAGTTAGAC
TACACCGTCC TACTCCACGA CGTTGCATCG CAGGAGATTA TCCCCTGGCA AATGCAAGTT
CTGTGGCACC CACAATACGG CACAAAAGTA AAGCACAACA GCCGCCTCCC AAAGGAAGCA
CCAGCAGAGT AAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_113843.1 CDS 170..841 Translation 
Target ORF information:
RefSeq Version NM_031655.1 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus latexin (Lxn), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_031655.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661ATGGAAGAAA TCCCACCCAC CCACTACGCT GCGTCCAGGG CTGCCTCGGT GGCAGAGAAC
TGTATAAATT ATCAGCAAGG GACCCCCAAC AAGGTATTCA AGGTGCAGAC GGTCCAGCAG
GCAAGCAAGG AGGATATCCC AGGAAGAGGC CACAAGTACC ATCTGAAGTT TTCTGTGGAA
GAAATTATCC AAAAACAAGT TACAGTGAGC TGCACGGCTG AAGTTCTTTA CCCTCGAATG
GGACAAGGCT CTGCACCGGA AGTCAACTTC ACATTTGAAG GAGAAATCGG CAAGAACCCA
GATGAGGAAG ACAACACGTT TTATCAAAGA CTCATGTCCA TGAAGGAACC ACTACAAGCA
CAAAATATTC CAGACAATTT TGGAAATGTG TCTCCACAAA TGAAGCCGGT CCACCACTTA
GCCTGGGTCG CCTGTGGTTA TGTAATGTGG CAGAACTCGA CTGAAGACAC ATGGTATAAA
ATGGCAAAGA TTCAAACGGT CAAGCAAGTG CAAAGAAACG ATGACTTCAT TGAGTTAGAC
TACACCGTCC TACTCCACGA CGTTGCATCG CAGGAGATTA TCCCCTGGCA AATGCAAGTT
CTGTGGCACC CACAATACGG CACAAAAGTA AAGCACAACA GCCGCCTCCC AAAGGAAGCA
CCAGCAGAGT AAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Nerve injury evoked loss of latexin expression in spinal cord neurons contributes to the development of neuropathic pain.
PloS one6(4)e19270(2011 Apr)
Kühlein HN,Tegeder I,Möser C,Lim HY,Häussler A,Spieth K,Jennes I,Marschalek R,Beckhaus T,Karas M,Fauth M,Ehnert C,Geisslinger G,Niederberger E
Reduced pain sensitivity in mice lacking latexin, an inhibitor of metallocarboxypeptidases.
Brain research1075(1)117-21(2006 Feb)
Jin M,Ishida M,Katoh-Fukui Y,Tsuchiya R,Higashinakagawa T,Ikegami S,Arimatsu Y
Genomic organization and regulatory elements of the rat latexin gene, which is expressed in a cell type-specific manner in both central and peripheral nervous systems.
Brain research. Molecular brain research69(1)62-72(1999 May)
Miyasaka N,Hatanaka Y,Jin M,Arimatsu Y
Purification, cDNA cloning, functional expression, and characterization of a 26-kDa endogenous mammalian carboxypeptidase inhibitor.
Proceedings of the National Academy of Sciences of the United States of America92(26)12225-9(1995 Dec)
Normant E,Martres MP,Schwartz JC,Gros C
Intracortical regionality represented by specific transcription for a novel protein, latexin.
The European journal of neuroscience6(6)973-82(1994 Jun)
Hatanaka Y,Uratani Y,Takiguchi-Hayashi K,Omori A,Sato K,Miyamoto M,Arimatsu Y
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