Slco1b2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slco1b2
Entrez Gene ID	58978
Full Name	solute carrier organic anion transporter family, member 1B2
Synonyms	OATP-4,Oatp4,Slc21a10,Slco1b3,rlst-1
General protein information	Preferred Names solute carrier organic anion transporter family, member 1B2 Names solute carrier organic anion transporter family member 1B2 liver-specific organic anion transporter 1 liver-specific transporter-1 organic anion transporting polypeptide 4 sodium-independent organic anion-transporting polypeptide 4 solute carrier family (organic anion transporter) member 10 solute carrier family 21 (organic anion transporter) member 10 solute carrier family 21 member 10 solute carrier organic anion transporter family, member 1b3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q44
Summary	mediated uptake of a variety of organic anions including taurocholate, bromosulfophthalein and steroid conjugates [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001270587.1	NP_001257516.1	solute carrier organic anion transporter family member 1B2 isoform 3
NM_031650.3	NP_113838.1	solute carrier organic anion transporter family member 1B2 isoform 1
NM_001270586.1	NP_001257515.1	solute carrier organic anion transporter family member 1B2 isoform 2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	SLCO1B3	NP_991373.1
Homo sapiens (human)	SLCO1B3	NP_062818.1
Macaca mulatta (Rhesus monkey)	SLCO1B3	NP_001028113.1
Mus musculus (house mouse)	Slco1b2	NP_065241.1
Rattus norvegicus (Norway rat)	Slco1b2	NP_113838.1
Canis lupus familiaris (dog)	SLCO1B3	NP_001159519.1

Gene Ontology
Bibliography

Related articles in PubMed

The relationship of polymorphisms in ABCC2 and SLCO1B3 with docetaxel pharmacokinetics and neutropenia: CALGB 60805 (Alliance).
Lewis LD, Miller AA, Owzar K, Bies RR, Markova S, Jiang C, Kroetz DL, Egorin MJ, McLeod HL, Ratain MJ,
Pharmacogenetics and genomics23(1)29-33(2013 Jan)

The involvement of organic anion transporting polypeptide in the hepatic uptake of telmisartan in rats: PET studies with [¹¹C]telmisartan.
Takashima T, Hashizume Y, Katayama Y, Murai M, Wada Y, Maeda K, Sugiyama Y, Watanabe Y
Molecular pharmaceutics8(5)1789-98(2011 Oct)

Use of mRNA expression to detect the induction of drug metabolising enzymes in rat and human hepatocytes.
Richert L, Tuschl G, Abadie C, Blanchard N, Pekthong D, Mantion G, Weber JC, Mueller SO
Toxicology and applied pharmacology235(1)86-96(2009 Feb)

Kinetic analysis of saturable hepatic uptake of digoxin and its inhibition by rifampicin.
Weiss M, Hung DY, Poenicke K, Roberts MS
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences34(4-5)345-50(2008 Aug)

Effect of aminoguanidine on lipopolysaccharide-induced changes in rat liver transporters and transcription factors.
Aoki K, Nakajima M, Hoshi Y, Saso N, Kato S, Sugiyama Y, Sato H
Biological & pharmaceutical bulletin31(3)412-20(2008 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Slco1b2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slco1b2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa08375	NM_031650.3 Latest version!	Rattus norvegicus solute carrier organic anion transporter family member 1B2 (Slco1b2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
ORa09328	NM_001270586.1 Latest version!	Rattus norvegicus solute carrier organic anion transporter family member 1B2 (Slco1b2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa09331	NM_001270587.1 Latest version!	Rattus norvegicus solute carrier organic anion transporter family member 1B2 (Slco1b2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slco1b2 ( NM_031650.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_113838.1 Rattus norvegicus solute carrier organic anion transporter family member 1B2 (Slco1b2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa08375
Clone ID Related Accession (Same CDS sequence)	NM_031650.3
Accession Version	NM_031650.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2064bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1574092800000
Organism	Rattus norvegicus(Norway rat)
Product	solute carrier organic anion transporter family member 1B2 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF208545.2 and AABR07062416.1. On Jul 19, 2012 this sequence version replaced NM_031650.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ271682.1, AF208545.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689598, SAMN01906349 [ECO:0000348] ##Evidence-Data-END##

ATGGACCACA CTCAGCAGTC AAGGAAAGCT GCAGAGGCCC AACCTTCACG ATCAAAGCAA 
ACAAGGTTCT GCGATGGATT CAAGCTATTT TTGGCAGCCC TCTCCTTCAG CTACATATGC 
AAAGCACTAG GTGGAGTTGT TATGAAGAGT TCCATCACCC AAATCGAAAG AAGATTCGAC 
ATACCATCTT CCATTTCTGG TTTGATTGAT GGAGGCTTTG AAATTGGGAA TTTATTAGTT 
ATTGTATTTG TGAGTTACTT TGGATCCAAA CTACACAGGC CAAAGCTGAT TGGAATTGGC 
TGCTTCATCA TGGGCATTGG GAGCATTTTG ACAGCGTTGC CACATTTCTT CATGGGATAT 
TACAAGTATG CAAAAGAAAA CGACATTGGC TCTCTAGGCA ACTCTACATT GACCTGTTTC 
ATCAATCAAA TGACATCACC CACTGGACCT TCACCTGAGA TAGTGGAGAA AGGTTGTGAA 
AAGGGGTTAA AGTCACACAT GTGGATTTAT GTCTTGATGG GGAACATGCT TCGTGGGATA 
GGGGAAACAC CAATAGTGCC CCTGGGAATT TCCTACCTTG ATGACTTTGC AAAAGAAGGG 
CACACTTCCA TGCACCTAGG TACTCTGCAT ACTATAGCAA TGATTGGACC AATCCTTGGC 
TTTATCATGT CATCTGTGTT TGCTAAGATA TATGTAGACG TTGGATATGT AGACCTGAAC 
AGTGTCCGAA TAACTCCTAA TGATGCTCGT TGGGTTGGTG CCTGGTGGCT CAGCTTCATT 
GTGAATGGAC TATTATGCAT TACTTCTTCC ATACCCTTCT TTTTTCTGCC CAAAATTCCA 
AAGAGGTCAC AGGAGGAAAG GAAAAATTCA GTATCTCTTC ATGCACCCAA AACAGATGAG 
GAGAAGAAAC ACATGACTAA TTTAACAAAG CAAGAGGAAC AAGATCCTTC CAACATGACT 
GGTTTTCTAA GGTCTCTGAG AAGCATCCTT ACCAATGAAA TATATGTTAT ATTCTTGATA 
CTGACGTTAC TACAAGTCAG CGGCTTCATT GGCTCCTTTA CTTACCTGTT CAAGTTCATA 
GAGCAGCAGT TCGGCCGGAC AGCATCTCAG GCCAACTTCT TGTTAGGAAT TATAACCATA 
CCTACTATGG CAACTGCAAT GTTTTTAGGA GGATATATTG TTAAAAAATT CAAATTGACA 
TCGGTTGGAA TCGCCAAGTT TGTATTTTTC ACCTCCTCAG TGGCCTATGC GTTTCAGTTC 
TTATATTTTC CTCTACTCTG TGAAAACAAG CCATTTGCTG GCCTAACCTT GACCTACGAT 
GGAATGAACC CAGTGGACTC TCACATAGAT GTACCACTTT CTTATTGTAA CTCGGACTGC 
AGTTGTGATA AAAATCAATG GGAACCCATC TGTGGGGAAA ATGGAGTCAC TTACATTTCA 
CCTTGTCTGG CAGGATGCAA ATCTTTTCGT GGTGATAAGA AGCCGAATAA CACAGAGTTC 
TATGACTGCA GTTGTATCAG CAACTCTGGA AACAACTCAG CACATTTGGG TGAATGCCCA 
AGATACAAAT GCAAAACCAA CTATTACTTT TATATAATTC TTCAAGTCAC TGTGTCCTTT 
TTCACTGCAA TGGGAAGCCC ATCTTTAATC TTGATTCTGA TGAAGAGCGT CCAACCTGAA 
TTGAAATCAC TTGCAATGGG TTTCCATTCA CTGATTATTC GAGCACTAGG AGGGATTCTA 
GCTCCAATCT ATTATGGGGC ATTCATTGAC AGAACGTGTA TTAAGTGGTC TGTCACCAGC 
TGTGGAAAAC GTGGTGCATG TAGGCTATAT AACTCCAGAT TATTTGGATT CTCCTACTTG 
GGTTTGAACT TAGCTTTAAA AACTCCACCA CTTTTTTTAT ATGTTGTATT AATTTATTTC 
ACAAAGAGAA AATATAAAAG AAATGATAAC AAGACATTGG AAAATGGAAG ACAGTTCACA 
GATGAAGGAA ACCCAGATTC TGTAAATAAA AATGGATACT ATTGTGTACC TTATGATGAA 
CAAAGCAATG AAACACCTCT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113838.1
CDS	115..2178
Translation	MDHTQQSRKAAEAQPSRSKQTRFCDGFKLFLAALSFSYICKALGGVVMKSSITQIERRFDIPSSISGLIDGGFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGSILTALPHFFMGYYKYAKENDIGSLGNSTLTCFINQMTSPTGPSPEIVEKGCEKGLKSHMWIYVLMGNMLRGIGETPIVPLGISYLDDFAKEGHTSMHLGTLHTIAMIGPILGFIMSSVFAKIYVDVGYVDLNSVRITPNDARWVGAWWLSFIVNGLLCITSSIPFFFLPKIPKRSQEERKNSVSLHAPKTDEEKKHMTNLTKQEEQDPSNMTGFLRSLRSILTNEIYVIFLILTLLQVSGFIGSFTYLFKFIEQQFGRTASQANFLLGIITIPTMATAMFLGGYIVKKFKLTSVGIAKFVFFTSSVAYAFQFLYFPLLCENKPFAGLTLTYDGMNPVDSHIDVPLSYCNSDCSCDKNQWEPICGENGVTYISPCLAGCKSFRGDKKPNNTEFYDCSCISNSGNNSAHLGECPRYKCKTNYYFYIILQVTVSFFTAMGSPSLILILMKSVQPELKSLAMGFHSLIIRALGGILAPIYYGAFIDRTCIKWSVTSCGKRGACRLYNSRLFGFSYLGLNLALKTPPLFLYVVLIYFTKRKYKRNDNKTLENGRQFTDEGNPDSVNKNGYYCVPYDEQSNETPL

Target ORF information:

RefSeq Version	NM_031650.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier organic anion transporter family member 1B2 (Slco1b2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031650.3

ORF Insert Sequence:

ATGGACCACA CTCAGCAGTC AAGGAAAGCT GCAGAGGCCC AACCTTCACG ATCAAAGCAA 
ACAAGGTTCT GCGATGGATT CAAGCTATTT TTGGCAGCCC TCTCCTTCAG CTACATATGC 
AAAGCACTAG GTGGAGTTGT TATGAAGAGT TCCATCACCC AAATCGAAAG AAGATTCGAC 
ATACCATCTT CCATTTCTGG TTTGATTGAT GGAGGCTTTG AAATTGGGAA TTTATTAGTT 
ATTGTATTTG TGAGTTACTT TGGATCCAAA CTACACAGGC CAAAGCTGAT TGGAATTGGC 
TGCTTCATCA TGGGCATTGG GAGCATTTTG ACAGCGTTGC CACATTTCTT CATGGGATAT 
TACAAGTATG CAAAAGAAAA CGACATTGGC TCTCTAGGCA ACTCTACATT GACCTGTTTC 
ATCAATCAAA TGACATCACC CACTGGACCT TCACCTGAGA TAGTGGAGAA AGGTTGTGAA 
AAGGGGTTAA AGTCACACAT GTGGATTTAT GTCTTGATGG GGAACATGCT TCGTGGGATA 
GGGGAAACAC CAATAGTGCC CCTGGGAATT TCCTACCTTG ATGACTTTGC AAAAGAAGGG 
CACACTTCCA TGCACCTAGG TACTCTGCAT ACTATAGCAA TGATTGGACC AATCCTTGGC 
TTTATCATGT CATCTGTGTT TGCTAAGATA TATGTAGACG TTGGATATGT AGACCTGAAC 
AGTGTCCGAA TAACTCCTAA TGATGCTCGT TGGGTTGGTG CCTGGTGGCT CAGCTTCATT 
GTGAATGGAC TATTATGCAT TACTTCTTCC ATACCCTTCT TTTTTCTGCC CAAAATTCCA 
AAGAGGTCAC AGGAGGAAAG GAAAAATTCA GTATCTCTTC ATGCACCCAA AACAGATGAG 
GAGAAGAAAC ACATGACTAA TTTAACAAAG CAAGAGGAAC AAGATCCTTC CAACATGACT 
GGTTTTCTAA GGTCTCTGAG AAGCATCCTT ACCAATGAAA TATATGTTAT ATTCTTGATA 
CTGACGTTAC TACAAGTCAG CGGCTTCATT GGCTCCTTTA CTTACCTGTT CAAGTTCATA 
GAGCAGCAGT TCGGCCGGAC AGCATCTCAG GCCAACTTCT TGTTAGGAAT TATAACCATA 
CCTACTATGG CAACTGCAAT GTTTTTAGGA GGATATATTG TTAAAAAATT CAAATTGACA 
TCGGTTGGAA TCGCCAAGTT TGTATTTTTC ACCTCCTCAG TGGCCTATGC GTTTCAGTTC 
TTATATTTTC CTCTACTCTG TGAAAACAAG CCATTTGCTG GCCTAACCTT GACCTACGAT 
GGAATGAACC CAGTGGACTC TCACATAGAT GTACCACTTT CTTATTGTAA CTCGGACTGC 
AGTTGTGATA AAAATCAATG GGAACCCATC TGTGGGGAAA ATGGAGTCAC TTACATTTCA 
CCTTGTCTGG CAGGATGCAA ATCTTTTCGT GGTGATAAGA AGCCGAATAA CACAGAGTTC 
TATGACTGCA GTTGTATCAG CAACTCTGGA AACAACTCAG CACATTTGGG TGAATGCCCA 
AGATACAAAT GCAAAACCAA CTATTACTTT TATATAATTC TTCAAGTCAC TGTGTCCTTT 
TTCACTGCAA TGGGAAGCCC ATCTTTAATC TTGATTCTGA TGAAGAGCGT CCAACCTGAA 
TTGAAATCAC TTGCAATGGG TTTCCATTCA CTGATTATTC GAGCACTAGG AGGGATTCTA 
GCTCCAATCT ATTATGGGGC ATTCATTGAC AGAACGTGTA TTAAGTGGTC TGTCACCAGC 
TGTGGAAAAC GTGGTGCATG TAGGCTATAT AACTCCAGAT TATTTGGATT CTCCTACTTG 
GGTTTGAACT TAGCTTTAAA AACTCCACCA CTTTTTTTAT ATGTTGTATT AATTTATTTC 
ACAAAGAGAA AATATAAAAG AAATGATAAC AAGACATTGG AAAATGGAAG ACAGTTCACA 
GATGAAGGAA ACCCAGATTC TGTAAATAAA AATGGATACT ATTGTGTACC TTATGATGAA 
CAAAGCAATG AAACACCTCT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slco1b2 ( NM_001270586.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001257515.1 Rattus norvegicus solute carrier organic anion transporter family member 1B2 (Slco1b2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ORa09328
Clone ID Related Accession (Same CDS sequence)	NM_001270586.1
Accession Version	NM_001270586.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1959bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1574092800000
Organism	Rattus norvegicus(Norway rat)
Product	solute carrier organic anion transporter family member 1B2 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF217450.2, AF147740.1 and AABR07062416.1. Transcript Variant: This variant (2, also known as rlst-1b) uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AF147740.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA2689598, SAMN01906349 [ECO:0000348] ##Evidence-Data-END##

ATGGACCACA CTCAGCAGTC AAGGAAAGCT GCAGAGGCCC AACCTTCACG ATCAAAGCAA 
ACAAGGTTCT GCGATGGATT CAAGCTATTT TTGGCAGCCC TCTCCTTCAG CTACATATGC 
AAAGCACTAG GTGGAGTTGT TATGAAGAGT TCCATCACCC AAATCGAAAG AAGATTCGAC 
ATACCATCTT CCATTTCTGG TTTGATTGAT GGAGGCTTTG AAATTGGGAA TTTATTAGTT 
ATTGTATTTG TGAGTTACTT TGGATCCAAA CTACACAGGC CAAAGCTGAT TGGAATTGGC 
TGCTTCATCA TGGGCATTGG GAGCATTTTG ACAGCGTTGC CACATTTCTT CATGGGATAT 
TACAAGTATG CAAAAGAAAA CGACATTGGC TCTCTAGGCA ACTCTACATT GACCTGTTTC 
ATCAATCAAA TGACATCACC CACTGGACCT TCACCTGAGA TAGTGGAGAA AGGTTGTGAA 
AAGGGGTTAA AGTCACACAT GTGGATTTAT GTCTTGATGG GGAACATGCT TCGTGGGATA 
GGGGAAACAC CAATAGTGCC CCTGGGAATT TCCTACCTTG ATGACTTTGC AAAAGAAGGG 
CACACTTCCA TGCACCTAGG TACTCTGCAT ACTATAGCAA TGATTGGACC AATCCTTGGC 
TTTATCATGT CATCTGTGTT TGCTAAGATA TATGTAGACG TTGGATATGT AGACCTGAAC 
AGTGTCCGAA TAACTCCTAA TGATGCTCGT TGGGTTGGTG CCTGGTGGCT CAGCTTCATT 
GTGAATGGAC TATTATGCAT TACTTCTTCC ATACCCTTCT TTTTTCTGCC CAAAATTCCA 
AAGAGGTCAC AGGAGGAAAG GAAAAATTCA GTATCTCTTC ATGCACCCAA AACAGATGAG 
GAGAAGAAAC ACATGACTAA TTTAACAAAG CAAGAGGAAC AAGATCCTTC CAACATGACT 
GGTTTTCTAA GGTCTCTGAG AAGCATCCTT ACCAATGAAA TATATGTTAT ATTCTTGATA 
CTGACGTTAC TACAAGTCAG CGGCTTCATT GGCTCCTTTA CTTACCTGTT CAAGTTCATA 
GAGCAGCAGT TCGGCCGGAC AGCATCTCAG GCCAACTTCT TGTTAGGAAT TATAACCATA 
CCTACTATGG CAACTGCAAT GTTTTTAGGA GGATATATTG TTAAAAAATT CAAATTGACA 
TCGGTTGGAA TCGCCAAAAT GAACCCAGTG GACTCTCACA TAGATGTACC ACTTTCTTAT 
TGTAACTCGG ACTGCAGTTG TGATAAAAAT CAATGGGAAC CCATCTGTGG GGAAAATGGA 
GTCACTTACA TTTCACCTTG TCTGGCAGGA TGCAAATCTT TTCGTGGTGA TAAGAAGCCG 
AATAACACAG AGTTCTATGA CTGCAGTTGT ATCAGCAACT CTGGAAACAA CTCAGCACAT 
TTGGGTGAAT GCCCAAGATA CAAATGCAAA ACCAACTATT ACTTTTATAT AATTCTTCAA 
GTCACTGTGT CCTTTTTCAC TGCAATGGGA AGCCCATCTT TAATCTTGAT TCTGATGAAG 
AGCGTCCAAC CTGAATTGAA ATCACTTGCA ATGGGTTTCC ATTCACTGAT TATTCGAGCA 
CTAGGAGGGA TTCTAGCTCC AATCTATTAT GGGGCATTCA TTGACAGAAC GTGTATTAAG 
TGGTCTGTCA CCAGCTGTGG AAAACGTGGT GCATGTAGGC TATATAACTC CAGATTATTT 
GGATTCTCCT ACTTGGGTTT GAACTTAGCT TTAAAAACTC CACCACTTTT TTTATATGTT 
GTATTAATTT ATTTCACAAA GAGAAAATAT AAAAGAAATG ATAACAAGAC ATTGGAAAAT 
GGAAGACAGT TCACAGATGA AGGAAACCCA GATTCTGTAA ATAAAAATGG ATACTATTGT 
GTACCTTATG ATGAACAAAG CAATGAAACA CCTCTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257515.1
CDS	115..2073
Translation	MDHTQQSRKAAEAQPSRSKQTRFCDGFKLFLAALSFSYICKALGGVVMKSSITQIERRFDIPSSISGLIDGGFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGSILTALPHFFMGYYKYAKENDIGSLGNSTLTCFINQMTSPTGPSPEIVEKGCEKGLKSHMWIYVLMGNMLRGIGETPIVPLGISYLDDFAKEGHTSMHLGTLHTIAMIGPILGFIMSSVFAKIYVDVGYVDLNSVRITPNDARWVGAWWLSFIVNGLLCITSSIPFFFLPKIPKRSQEERKNSVSLHAPKTDEEKKHMTNLTKQEEQDPSNMTGFLRSLRSILTNEIYVIFLILTLLQVSGFIGSFTYLFKFIEQQFGRTASQANFLLGIITIPTMATAMFLGGYIVKKFKLTSVGIAKMNPVDSHIDVPLSYCNSDCSCDKNQWEPICGENGVTYISPCLAGCKSFRGDKKPNNTEFYDCSCISNSGNNSAHLGECPRYKCKTNYYFYIILQVTVSFFTAMGSPSLILILMKSVQPELKSLAMGFHSLIIRALGGILAPIYYGAFIDRTCIKWSVTSCGKRGACRLYNSRLFGFSYLGLNLALKTPPLFLYVVLIYFTKRKYKRNDNKTLENGRQFTDEGNPDSVNKNGYYCVPYDEQSNETPL

Target ORF information:

RefSeq Version	NM_001270586.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier organic anion transporter family member 1B2 (Slco1b2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001270586.1

ORF Insert Sequence:

ATGGACCACA CTCAGCAGTC AAGGAAAGCT GCAGAGGCCC AACCTTCACG ATCAAAGCAA 
ACAAGGTTCT GCGATGGATT CAAGCTATTT TTGGCAGCCC TCTCCTTCAG CTACATATGC 
AAAGCACTAG GTGGAGTTGT TATGAAGAGT TCCATCACCC AAATCGAAAG AAGATTCGAC 
ATACCATCTT CCATTTCTGG TTTGATTGAT GGAGGCTTTG AAATTGGGAA TTTATTAGTT 
ATTGTATTTG TGAGTTACTT TGGATCCAAA CTACACAGGC CAAAGCTGAT TGGAATTGGC 
TGCTTCATCA TGGGCATTGG GAGCATTTTG ACAGCGTTGC CACATTTCTT CATGGGATAT 
TACAAGTATG CAAAAGAAAA CGACATTGGC TCTCTAGGCA ACTCTACATT GACCTGTTTC 
ATCAATCAAA TGACATCACC CACTGGACCT TCACCTGAGA TAGTGGAGAA AGGTTGTGAA 
AAGGGGTTAA AGTCACACAT GTGGATTTAT GTCTTGATGG GGAACATGCT TCGTGGGATA 
GGGGAAACAC CAATAGTGCC CCTGGGAATT TCCTACCTTG ATGACTTTGC AAAAGAAGGG 
CACACTTCCA TGCACCTAGG TACTCTGCAT ACTATAGCAA TGATTGGACC AATCCTTGGC 
TTTATCATGT CATCTGTGTT TGCTAAGATA TATGTAGACG TTGGATATGT AGACCTGAAC 
AGTGTCCGAA TAACTCCTAA TGATGCTCGT TGGGTTGGTG CCTGGTGGCT CAGCTTCATT 
GTGAATGGAC TATTATGCAT TACTTCTTCC ATACCCTTCT TTTTTCTGCC CAAAATTCCA 
AAGAGGTCAC AGGAGGAAAG GAAAAATTCA GTATCTCTTC ATGCACCCAA AACAGATGAG 
GAGAAGAAAC ACATGACTAA TTTAACAAAG CAAGAGGAAC AAGATCCTTC CAACATGACT 
GGTTTTCTAA GGTCTCTGAG AAGCATCCTT ACCAATGAAA TATATGTTAT ATTCTTGATA 
CTGACGTTAC TACAAGTCAG CGGCTTCATT GGCTCCTTTA CTTACCTGTT CAAGTTCATA 
GAGCAGCAGT TCGGCCGGAC AGCATCTCAG GCCAACTTCT TGTTAGGAAT TATAACCATA 
CCTACTATGG CAACTGCAAT GTTTTTAGGA GGATATATTG TTAAAAAATT CAAATTGACA 
TCGGTTGGAA TCGCCAAAAT GAACCCAGTG GACTCTCACA TAGATGTACC ACTTTCTTAT 
TGTAACTCGG ACTGCAGTTG TGATAAAAAT CAATGGGAAC CCATCTGTGG GGAAAATGGA 
GTCACTTACA TTTCACCTTG TCTGGCAGGA TGCAAATCTT TTCGTGGTGA TAAGAAGCCG 
AATAACACAG AGTTCTATGA CTGCAGTTGT ATCAGCAACT CTGGAAACAA CTCAGCACAT 
TTGGGTGAAT GCCCAAGATA CAAATGCAAA ACCAACTATT ACTTTTATAT AATTCTTCAA 
GTCACTGTGT CCTTTTTCAC TGCAATGGGA AGCCCATCTT TAATCTTGAT TCTGATGAAG 
AGCGTCCAAC CTGAATTGAA ATCACTTGCA ATGGGTTTCC ATTCACTGAT TATTCGAGCA 
CTAGGAGGGA TTCTAGCTCC AATCTATTAT GGGGCATTCA TTGACAGAAC GTGTATTAAG 
TGGTCTGTCA CCAGCTGTGG AAAACGTGGT GCATGTAGGC TATATAACTC CAGATTATTT 
GGATTCTCCT ACTTGGGTTT GAACTTAGCT TTAAAAACTC CACCACTTTT TTTATATGTT 
GTATTAATTT ATTTCACAAA GAGAAAATAT AAAAGAAATG ATAACAAGAC ATTGGAAAAT 
GGAAGACAGT TCACAGATGA AGGAAACCCA GATTCTGTAA ATAAAAATGG ATACTATTGT 
GTACCTTATG ATGAACAAAG CAATGAAACA CCTCTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slco1b2 ( NM_001270587.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001257516.1 Rattus norvegicus solute carrier organic anion transporter family member 1B2 (Slco1b2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	ORa09331
Clone ID Related Accession (Same CDS sequence)	NM_001270587.1
Accession Version	NM_001270587.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1965bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1574092800000
Organism	Rattus norvegicus(Norway rat)
Product	solute carrier organic anion transporter family member 1B2 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF217450.2 and AABR07062416.1. Transcript Variant: This variant (3, also known as rlst-1c) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF217450.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689598, SAMN01906353 [ECO:0000348] ##Evidence-Data-END##

ATGGACCACA CTCAGCAGTC AAGGAAAGCT GCAGAGGCCC AACCTTCACG ATCAAAGCAA 
ACAAGGTTCT GCGATGGATT CAAGCTATTT TTGGCAGCCC TCTCCTTCAG CTACATATGC 
AAAGCACTAG GTGGAGTTGT TATGAAGAGT TCCATCACCC AAATCGAAAG AAGATTCGAC 
ATACCATCTT CCATTTCTGG TTTGATTGAT GGAGGCTTTG AAATTGGGAA TTTATTAGTT 
ATTGTATTTG TGAGTTACTT TGGATCCAAA CTACACAGGC CAAAGCTGAT TGGAATTGGC 
TGCTTCATCA TGGGCATTGG GAGCATTTTG ACAGCGTTGC CACATTTCTT CATGGGATAT 
TACAAGTATG CAAAAGAAAA CGACATTGGC TCTCTAGGCA ACTCTACATT GACCTGTTTC 
ATCAATCAAA TGACATCACC CACTGGACCT TCACCTGAGA TAGTGGAGAA AGGTTGTGAA 
AAGGGGTTAA AGTCACACAT GTGGATTTAT GTCTTGATGG GGAACATGCT TCGTGGGATA 
GGGGAAACAC CAATAGTGCC CCTGGGAATT TCCTACCTTG ATGACTTTGC AAAAGAAGGG 
CACACTTCCA TGCACCTAGA CAGTGTCCGA ATAACTCCTA ATGATGCTCG TTGGGTTGGT 
GCCTGGTGGC TCAGCTTCAT TGTGAATGGA CTATTATGCA TTACTTCTTC CATACCCTTC 
TTTTTTCTGC CCAAAATTCC AAAGAGGTCA CAGGAGGAAA GGAAAAATTC AGTATCTCTT 
CATGCACCCA AAACAGATGA GGAGAAGAAA CACATGACTA ATTTAACAAA GCAAGAGGAA 
CAAGATCCTT CCAACATGAC TGGTTTTCTA AGGTCTCTGA GAAGCATCCT TACCAATGAA 
ATATATGTTA TATTCTTGAT ACTGACGTTA CTACAAGTCA GCGGCTTCAT TGGCTCCTTT 
ACTTACCTGT TCAAGTTCAT AGAGCAGCAG TTCGGCCGGA CAGCATCTCA GGCCAACTTC 
TTGTTAGGAA TTATAACCAT ACCTACTATG GCAACTGCAA TGTTTTTAGG AGGATATATT 
GTTAAAAAAT TCAAATTGAC ATCGGTTGGA ATCGCCAAGT TTGTATTTTT CACCTCCTCA 
GTGGCCTATG CGTTTCAGTT CTTATATTTT CCTCTACTCT GTGAAAACAA GCCATTTGCT 
GGCCTAACCT TGACCTACGA TGGAATGAAC CCAGTGGACT CTCACATAGA TGTACCACTT 
TCTTATTGTA ACTCGGACTG CAGTTGTGAT AAAAATCAAT GGGAACCCAT CTGTGGGGAA 
AATGGAGTCA CTTACATTTC ACCTTGTCTG GCAGGATGCA AATCTTTTCG TGGTGATAAG 
AAGCCGAATA ACACAGAGTT CTATGACTGC AGTTGTATCA GCAACTCTGG AAACAACTCA 
GCACATTTGG GTGAATGCCC AAGATACAAA TGCAAAACCA ACTATTACTT TTATATAATT 
CTTCAAGTCA CTGTGTCCTT TTTCACTGCA ATGGGAAGCC CATCTTTAAT CTTGATTCTG 
ATGAAGAGCG TCCAACCTGA ATTGAAATCA CTTGCAATGG GTTTCCATTC ACTGATTATT 
CGAGCACTAG GAGGGATTCT AGCTCCAATC TATTATGGGG CATTCATTGA CAGAACGTGT 
ATTAAGTGGT CTGTCACCAG CTGTGGAAAA CGTGGTGCAT GTAGGCTATA TAACTCCAGA 
TTATTTGGAT TCTCCTACTT GGGTTTGAAC TTAGCTTTAA AAACTCCACC ACTTTTTTTA 
TATGTTGTAT TAATTTATTT CACAAAGAGA AAATATAAAA GAAATGATAA CAAGACATTG 
GAAAATGGAA GACAGTTCAC AGATGAAGGA AACCCAGATT CTGTAAATAA AAATGGATAC 
TATTGTGTAC CTTATGATGA ACAAAGCAAT GAAACACCTC TTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257516.1
CDS	115..2079
Translation	MDHTQQSRKAAEAQPSRSKQTRFCDGFKLFLAALSFSYICKALGGVVMKSSITQIERRFDIPSSISGLIDGGFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGSILTALPHFFMGYYKYAKENDIGSLGNSTLTCFINQMTSPTGPSPEIVEKGCEKGLKSHMWIYVLMGNMLRGIGETPIVPLGISYLDDFAKEGHTSMHLDSVRITPNDARWVGAWWLSFIVNGLLCITSSIPFFFLPKIPKRSQEERKNSVSLHAPKTDEEKKHMTNLTKQEEQDPSNMTGFLRSLRSILTNEIYVIFLILTLLQVSGFIGSFTYLFKFIEQQFGRTASQANFLLGIITIPTMATAMFLGGYIVKKFKLTSVGIAKFVFFTSSVAYAFQFLYFPLLCENKPFAGLTLTYDGMNPVDSHIDVPLSYCNSDCSCDKNQWEPICGENGVTYISPCLAGCKSFRGDKKPNNTEFYDCSCISNSGNNSAHLGECPRYKCKTNYYFYIILQVTVSFFTAMGSPSLILILMKSVQPELKSLAMGFHSLIIRALGGILAPIYYGAFIDRTCIKWSVTSCGKRGACRLYNSRLFGFSYLGLNLALKTPPLFLYVVLIYFTKRKYKRNDNKTLENGRQFTDEGNPDSVNKNGYYCVPYDEQSNETPL

Target ORF information:

RefSeq Version	NM_001270587.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier organic anion transporter family member 1B2 (Slco1b2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001270587.1

ORF Insert Sequence:

ATGGACCACA CTCAGCAGTC AAGGAAAGCT GCAGAGGCCC AACCTTCACG ATCAAAGCAA 
ACAAGGTTCT GCGATGGATT CAAGCTATTT TTGGCAGCCC TCTCCTTCAG CTACATATGC 
AAAGCACTAG GTGGAGTTGT TATGAAGAGT TCCATCACCC AAATCGAAAG AAGATTCGAC 
ATACCATCTT CCATTTCTGG TTTGATTGAT GGAGGCTTTG AAATTGGGAA TTTATTAGTT 
ATTGTATTTG TGAGTTACTT TGGATCCAAA CTACACAGGC CAAAGCTGAT TGGAATTGGC 
TGCTTCATCA TGGGCATTGG GAGCATTTTG ACAGCGTTGC CACATTTCTT CATGGGATAT 
TACAAGTATG CAAAAGAAAA CGACATTGGC TCTCTAGGCA ACTCTACATT GACCTGTTTC 
ATCAATCAAA TGACATCACC CACTGGACCT TCACCTGAGA TAGTGGAGAA AGGTTGTGAA 
AAGGGGTTAA AGTCACACAT GTGGATTTAT GTCTTGATGG GGAACATGCT TCGTGGGATA 
GGGGAAACAC CAATAGTGCC CCTGGGAATT TCCTACCTTG ATGACTTTGC AAAAGAAGGG 
CACACTTCCA TGCACCTAGA CAGTGTCCGA ATAACTCCTA ATGATGCTCG TTGGGTTGGT 
GCCTGGTGGC TCAGCTTCAT TGTGAATGGA CTATTATGCA TTACTTCTTC CATACCCTTC 
TTTTTTCTGC CCAAAATTCC AAAGAGGTCA CAGGAGGAAA GGAAAAATTC AGTATCTCTT 
CATGCACCCA AAACAGATGA GGAGAAGAAA CACATGACTA ATTTAACAAA GCAAGAGGAA 
CAAGATCCTT CCAACATGAC TGGTTTTCTA AGGTCTCTGA GAAGCATCCT TACCAATGAA 
ATATATGTTA TATTCTTGAT ACTGACGTTA CTACAAGTCA GCGGCTTCAT TGGCTCCTTT 
ACTTACCTGT TCAAGTTCAT AGAGCAGCAG TTCGGCCGGA CAGCATCTCA GGCCAACTTC 
TTGTTAGGAA TTATAACCAT ACCTACTATG GCAACTGCAA TGTTTTTAGG AGGATATATT 
GTTAAAAAAT TCAAATTGAC ATCGGTTGGA ATCGCCAAGT TTGTATTTTT CACCTCCTCA 
GTGGCCTATG CGTTTCAGTT CTTATATTTT CCTCTACTCT GTGAAAACAA GCCATTTGCT 
GGCCTAACCT TGACCTACGA TGGAATGAAC CCAGTGGACT CTCACATAGA TGTACCACTT 
TCTTATTGTA ACTCGGACTG CAGTTGTGAT AAAAATCAAT GGGAACCCAT CTGTGGGGAA 
AATGGAGTCA CTTACATTTC ACCTTGTCTG GCAGGATGCA AATCTTTTCG TGGTGATAAG 
AAGCCGAATA ACACAGAGTT CTATGACTGC AGTTGTATCA GCAACTCTGG AAACAACTCA 
GCACATTTGG GTGAATGCCC AAGATACAAA TGCAAAACCA ACTATTACTT TTATATAATT 
CTTCAAGTCA CTGTGTCCTT TTTCACTGCA ATGGGAAGCC CATCTTTAAT CTTGATTCTG 
ATGAAGAGCG TCCAACCTGA ATTGAAATCA CTTGCAATGG GTTTCCATTC ACTGATTATT 
CGAGCACTAG GAGGGATTCT AGCTCCAATC TATTATGGGG CATTCATTGA CAGAACGTGT 
ATTAAGTGGT CTGTCACCAG CTGTGGAAAA CGTGGTGCAT GTAGGCTATA TAACTCCAGA 
TTATTTGGAT TCTCCTACTT GGGTTTGAAC TTAGCTTTAA AAACTCCACC ACTTTTTTTA 
TATGTTGTAT TAATTTATTT CACAAAGAGA AAATATAAAA GAAATGATAA CAAGACATTG 
GAAAATGGAA GACAGTTCAC AGATGAAGGA AACCCAGATT CTGTAAATAA AAATGGATAC 
TATTGTGTAC CTTATGATGA ACAAAGCAAT GAAACACCTC TTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The relationship of polymorphisms in ABCC2 and SLCO1B3 with docetaxel pharmacokinetics and neutropenia: CALGB 60805 (Alliance).
Pharmacogenetics and genomics23(1)29-33(2013 Jan)
Lewis LD,Miller AA,Owzar K,Bies RR,Markova S,Jiang C,Kroetz DL,Egorin MJ,McLeod HL,Ratain MJ,

The involvement of organic anion transporting polypeptide in the hepatic uptake of telmisartan in rats: PET studies with [¹¹C]telmisartan.
Molecular pharmaceutics8(5)1789-98(2011 Oct)
Takashima T,Hashizume Y,Katayama Y,Murai M,Wada Y,Maeda K,Sugiyama Y,Watanabe Y

Use of mRNA expression to detect the induction of drug metabolising enzymes in rat and human hepatocytes.
Toxicology and applied pharmacology235(1)86-96(2009 Feb)
Richert L,Tuschl G,Abadie C,Blanchard N,Pekthong D,Mantion G,Weber JC,Mueller SO

Kinetic analysis of saturable hepatic uptake of digoxin and its inhibition by rifampicin.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences34(4-5)345-50(2008 Aug)
Weiss M,Hung DY,Poenicke K,Roberts MS

Effect of aminoguanidine on lipopolysaccharide-induced changes in rat liver transporters and transcription factors.
Biological & pharmaceutical bulletin31(3)412-20(2008 Mar)
Aoki K,Nakajima M,Hoshi Y,Saso N,Kato S,Sugiyama Y,Sato H

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

Slco1b2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM