| Gene Symbol | Adam3a |
| Entrez Gene ID | 57021 |
| Full Name | ADAM metallopeptidase domain 3A |
| Synonyms | Adam3,tMDCI |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | germ-cell specific metalloprotease-disintegrin that may play a role in cell-cell and cell-matrix interactions during spermatogenesis [RGD, Feb 2006]. |
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Adam3a cDNA ORF clone, Rattus norvegicus(Norway rat)
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Gene
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Clones
gRNAs
The following Adam3a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Adam3a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID ORa04775 Clone ID Related Accession (Same CDS sequence) NM_020302.2 Accession Version NM_020302.2 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 2223bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1555516800000 Organism Rattus norvegicus(Norway rat) Product ADAM metallopeptidase domain 3A precursor Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from Y07903.1. On Dec 24, 2015 this sequence version replaced NM_020302.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y07903.1, BC078839.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689604, SAMN02642708 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221ATGCTGCCGT TATTCCTGGT CCTCTCATGC CTAGGCCAAT TGATCGCCGT AGGCAAGGAC
ATAGAAACAC CACTTATACA GATCACAGTG CCAGAGAAAA TCGAGACCAA CATCAAGGAT
GCCAAGGAAT CAGAAACACA AGTCACTTAT GTGATCAGAA TTGAGGGCAA AGCATACACA
CTCCAACTTG AAAAACAGTC ATTTTTACAT CCACATTTTG TGACAAATTT GCATAACAAG
TTGGGAACAT TGCAACCATA TTTTTCTTTA GTAAAGAGTC ACTGCTTTTA TCAAGGACAT
GCTGTCGAGA TTCCAGCATC GACCGTGACA CTCAGCACTT GCTCAGGTCT CAGGGGCTTG
CTGCAGTTGG AGAACGTGAC TTACGGAATT GAACCCTTAG AGTCTTCAAC TACACTCGAA
CACATACTTT ATGAAATACA GAATCATAAA ATTGATTATT CTCCCTTAAA AGAAAACTAC
ACGAATTCCC AGGATGAAAG TGGGTCCTAC CGAATTCTCG TGAAACCATT GAAAAGTTCA
AACTCGAAAC TAAGGAAGAG AATTCTGACG GTAAAGATCA TCATGGATAA AGGCATGTTT
GACCACGTGG GCTCTGAGGT GGGAGTCGCG ACTCAGAAAG TTGTTCAGAT GTTTGGTCTC
ATTAACACTA TGTTTTCCCA GCTGAAGATG ACTGTGATGT TAAACTCTCT GGAGATCTGG
TCAGAAGAAA ACAAGATAGA AACAAATGGG GATGCTGATG AAGTCCTGCA AAGGTTTCTG
CTGTGGACAC ACAAGGAAAT GCCTCAAACA ACCAAGGAAA TAACCTACTT ACTCCTGTAT
AAGGACCATC CTGATTATGT GGGAGCGACA TATCATGGGA TGGCCTGCAA CCCAAAGTTC
ACAGCAGGAA TCGCTCTGCA CCCAAAGACG TTAGGTGTGG AGGGCTTTGC CATTGTTCTG
TCACAGTTGC TGGGAATTAA CCTGGGGCTG ACATACGATG ACATCTACAA TTGCTTCTGT
CGAGGAAGCA CATGCATAAT GAATCCTTCA GCAATACATT CCGAAGGCAT AAAGGTTTTT
AGCAGTTGCA GCATGGATGA ATTCAGGCAG CTGGCTTCAC AGCCTGACCT AGATTGCCTT
CTGAAGACAC AGGAGACAGA AGTTGTTGCC CTGCCCCAGG CTGCAAAAGT TTGTGGTAAC
TACATCCTGG AGCCCCCAGA GCAGTGTGAC TGTGGCCCAG CAGAGAGATG TTCTCATAAA
AAGTGCTGTA AGTCTGAGGA TTGTACCCTG CTTAGTGATG CAGAGTGTGG TTCTGGGGCG
TGCTGTGATA AAAGAACATG CAAGATAGCT GAAAGAGGAC GCCTATGTAG GAAAAGTACG
GACCAGTGCG ACTTCCCAGA ATTCTGCAAT GGGACGTCTG AATTCTGTGT AGCTGATATA
AAAGCTGCGG ACCTGGAACC TTGCAACAAT GAAACCGCCT ATTGCTTCAA AGGGGTTTGC
CAAGACCGCG ACAGGCAGTG CACAGACTTA TTTGGAAAAT ATGCTAAGGG TCCTAATTAT
GTGTGTGCAC AAGAAGTGAA TCTGCAGAAT GACAAATTTG GAAACTGTCA TGGGCGCTGT
AATTATAGTG CTCTATTTTG TGGAAAAGCA GTTTGTTACT GGAGCTTTGC AGAACTCGTG
AAAACAGACG TATTTGATGT TCAATATACT TACTTGGGAG GCCAAGTGTG TGTGTCCGCA
CATTTAAGAG TAAGGAATGA TGAGACCAAG GATGACACAT ATGTCCGTGA TGGCACTATT
TGTGGTAATG GCCAGGTGTG TTACCGAGGG GAGTGCTTGC GTGTGCACGT CCTGAGGGGG
GATAGGGAGT GTGAGGCCGA TGACAAATGC CAAGGACATG GGATTTGCAA CAATCAAAAC
AACTGTCAAT GTGAAGCTGG TTTCGCTCCT CCAGAATGTG ACATGACCCC TTCATCTCCA
GGAGGGAGCA TGGACGATGG ATTTTGGCTG CCCTTAGATA AAAGCACACC GTTGGTTATC
AAGCGGCCTG GCACTCAATA TAAAAAGGGA CTTTTGATCA GTTTCTATGT CTTCCTGCCT
TTTCTCATTG TGACAGCCAT TATGGTTGTT AAGCAGAATA TCTCAAAGAT GTTCGGGCAA
GGAGAGGAAG AGTTTAGTGA AGGATCCATA TCAGAAGAAA TTAACGACAG CAAGCAGTCA
TAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_064698.1 CDS 111..2333 Translation 
Target ORF information:
RefSeq Version NM_020302.2 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus ADAM metallopeptidase domain 3A (Adam3a), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_020302.2
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221ATGCTGCCGT TATTCCTGGT CCTCTCATGC CTAGGCCAAT TGATCGCCGT AGGCAAGGAC
ATAGAAACAC CACTTATACA GATCACAGTG CCAGAGAAAA TCGAGACCAA CATCAAGGAT
GCCAAGGAAT CAGAAACACA AGTCACTTAT GTGATCAGAA TTGAGGGCAA AGCATACACA
CTCCAACTTG AAAAACAGTC ATTTTTACAT CCACATTTTG TGACAAATTT GCATAACAAG
TTGGGAACAT TGCAACCATA TTTTTCTTTA GTAAAGAGTC ACTGCTTTTA TCAAGGACAT
GCTGTCGAGA TTCCAGCATC GACCGTGACA CTCAGCACTT GCTCAGGTCT CAGGGGCTTG
CTGCAGTTGG AGAACGTGAC TTACGGAATT GAACCCTTAG AGTCTTCAAC TACACTCGAA
CACATACTTT ATGAAATACA GAATCATAAA ATTGATTATT CTCCCTTAAA AGAAAACTAC
ACGAATTCCC AGGATGAAAG TGGGTCCTAC CGAATTCTCG TGAAACCATT GAAAAGTTCA
AACTCGAAAC TAAGGAAGAG AATTCTGACG GTAAAGATCA TCATGGATAA AGGCATGTTT
GACCACGTGG GCTCTGAGGT GGGAGTCGCG ACTCAGAAAG TTGTTCAGAT GTTTGGTCTC
ATTAACACTA TGTTTTCCCA GCTGAAGATG ACTGTGATGT TAAACTCTCT GGAGATCTGG
TCAGAAGAAA ACAAGATAGA AACAAATGGG GATGCTGATG AAGTCCTGCA AAGGTTTCTG
CTGTGGACAC ACAAGGAAAT GCCTCAAACA ACCAAGGAAA TAACCTACTT ACTCCTGTAT
AAGGACCATC CTGATTATGT GGGAGCGACA TATCATGGGA TGGCCTGCAA CCCAAAGTTC
ACAGCAGGAA TCGCTCTGCA CCCAAAGACG TTAGGTGTGG AGGGCTTTGC CATTGTTCTG
TCACAGTTGC TGGGAATTAA CCTGGGGCTG ACATACGATG ACATCTACAA TTGCTTCTGT
CGAGGAAGCA CATGCATAAT GAATCCTTCA GCAATACATT CCGAAGGCAT AAAGGTTTTT
AGCAGTTGCA GCATGGATGA ATTCAGGCAG CTGGCTTCAC AGCCTGACCT AGATTGCCTT
CTGAAGACAC AGGAGACAGA AGTTGTTGCC CTGCCCCAGG CTGCAAAAGT TTGTGGTAAC
TACATCCTGG AGCCCCCAGA GCAGTGTGAC TGTGGCCCAG CAGAGAGATG TTCTCATAAA
AAGTGCTGTA AGTCTGAGGA TTGTACCCTG CTTAGTGATG CAGAGTGTGG TTCTGGGGCG
TGCTGTGATA AAAGAACATG CAAGATAGCT GAAAGAGGAC GCCTATGTAG GAAAAGTACG
GACCAGTGCG ACTTCCCAGA ATTCTGCAAT GGGACGTCTG AATTCTGTGT AGCTGATATA
AAAGCTGCGG ACCTGGAACC TTGCAACAAT GAAACCGCCT ATTGCTTCAA AGGGGTTTGC
CAAGACCGCG ACAGGCAGTG CACAGACTTA TTTGGAAAAT ATGCTAAGGG TCCTAATTAT
GTGTGTGCAC AAGAAGTGAA TCTGCAGAAT GACAAATTTG GAAACTGTCA TGGGCGCTGT
AATTATAGTG CTCTATTTTG TGGAAAAGCA GTTTGTTACT GGAGCTTTGC AGAACTCGTG
AAAACAGACG TATTTGATGT TCAATATACT TACTTGGGAG GCCAAGTGTG TGTGTCCGCA
CATTTAAGAG TAAGGAATGA TGAGACCAAG GATGACACAT ATGTCCGTGA TGGCACTATT
TGTGGTAATG GCCAGGTGTG TTACCGAGGG GAGTGCTTGC GTGTGCACGT CCTGAGGGGG
GATAGGGAGT GTGAGGCCGA TGACAAATGC CAAGGACATG GGATTTGCAA CAATCAAAAC
AACTGTCAAT GTGAAGCTGG TTTCGCTCCT CCAGAATGTG ACATGACCCC TTCATCTCCA
GGAGGGAGCA TGGACGATGG ATTTTGGCTG CCCTTAGATA AAAGCACACC GTTGGTTATC
AAGCGGCCTG GCACTCAATA TAAAAAGGGA CTTTTGATCA GTTTCTATGT CTTCCTGCCT
TTTCTCATTG TGACAGCCAT TATGGTTGTT AAGCAGAATA TCTCAAAGAT GTTCGGGCAA
GGAGAGGAAG AGTTTAGTGA AGGATCCATA TCAGAAGAAA TTAACGACAG CAAGCAGTCA
TAGThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Identification of multiple DNA copy number alterations including frequent 8p11.22 amplification in conjunctival squamous cell carcinoma.
Investigative ophthalmology & visual science55(12)8604-13(2014 Dec)
Asnaghi L,Alkatan H,Mahale A,Othman M,Alwadani S,Al-Hussain H,Jastaneiah S,Yu W,Maktabi A,Edward DP,Eberhart CG
GPI-anchored protein complex, LY6K/TEX101, is required for sperm migration into the oviduct and male fertility in mice.
Biology of reproduction90(3)60(2014 Mar)
Fujihara Y,Okabe M,Ikawa M
Mice expressing aberrant sperm-specific protein PMIS2 produce normal-looking but fertilization-incompetent spermatozoa.
Molecular biology of the cell23(14)2671-9(2012 Jul)
Yamaguchi R,Fujihara Y,Ikawa M,Okabe M
Protein disulfide isomerase homolog PDILT is required for quality control of sperm membrane protein ADAM3 and male fertility [corrected].
Proceedings of the National Academy of Sciences of the United States of America109(10)3850-5(2012 Mar)
Tokuhiro K,Ikawa M,Benham AM,Okabe M
Lack of tyrosylprotein sulfotransferase-2 activity results in altered sperm-egg interactions and loss of ADAM3 and ADAM6 in epididymal sperm.
The Journal of biological chemistry286(15)13060-70(2011 Apr)
Marcello MR,Jia W,Leary JA,Moore KL,Evans JP
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