Fasn cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fasn
Entrez Gene ID	50671
Full Name	fatty acid synthase
General protein information	Preferred Names fatty acid synthase Names fatty acid synthase
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q32.3
Summary	plays a role in lipid biosynthesis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_017332.1	NP_059028.1	fatty acid synthase

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Fasn	NP_059028.1
Xenopus tropicalis (tropical clawed frog)	fasn	XP_002937357.2
Canis lupus familiaris (dog)	FASN	XP_005624202.1
Bos taurus (cattle)	FASN	NP_001012687.1
Mus musculus (house mouse)	Fasn	NP_032014.3
Macaca mulatta (Rhesus monkey)	FASN	XP_001113076.1
Caenorhabditis elegans (roundworm)	fasn-1	NP_492417.2
Homo sapiens (human)	FASN	NP_004095.4
Drosophila melanogaster (fruit fly)	v(2)k05816	NP_647613.1
Pan troglodytes (chimpanzee)	FASN	XP_511758.2
Gallus gallus (chicken)	FASN	NP_990486.2

Gene Ontology
Bibliography

Related articles in PubMed

Interleukin-15 derived from Guanylin-GC-C-expressing macrophages inhibits fatty acid synthase in adipocytes.
Akieda-Asai S, Ida T, Miyazato M, Kangawa K, Date Y
Peptides9914-19(2018 01)

Prenatal caloric restriction alters lipid metabolism but not hepatic Fasn gene expression and methylation profiles in rats.
Nowacka-Woszuk J, Madeja ZE, Chmurzynska A
BMC genetics18(1)78(2017 08)

Type of supplemented simple sugar, not merely calorie intake, determines adverse effects on metabolism and aortic function in female rats.
Sangüesa G, Shaligram S, Akther F, Roglans N, Laguna JC, Rahimian R, Alegret M
American journal of physiology. Heart and circulatory physiology312(2)H289-H304(2017 Feb)

Histone modifications in FASN modulated by sterol regulatory element-binding protein 1c and carbohydrate responsive-element binding protein under insulin stimulation are related to NAFLD.
Du X, Cai C, Yao J, Zhou Y, Yu H, Shen W
Biochemical and biophysical research communications483(1)409-417(2017 01)

Short term exendin-4 treatment reduces markers of metabolic disorders in female offspring of obese rat dams.
Chan YL, Saad S, Simar D, Oliver B, McGrath K, Reyk Dv, Bertrand PP, Gorrie C, Pollock C, Chen H
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience4667-75(2015 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Fasn gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fasn cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13045	NM_017332.1 Latest version!	Rattus norvegicus fatty acid synthase (Fasn), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	29-31	$1301.30 $1859.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fasn ( NM_017332.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_059028.1 Rattus norvegicus fatty acid synthase (Fasn), mRNA.

Price & Availability↑

CloneID	ORa13045
Clone ID Related Accession (Same CDS sequence)	NM_017332.1
Accession Version	NM_017332.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 7518bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Rattus norvegicus(Norway rat)
Product	fatty acid synthase
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M76767.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M76767.1, X62888.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGAGGAGG TGGTGATAGC CGGTATGTCC GGGAAATTGC CCGAGTCAGA GAACCTGCAG 
GAGTTCTGGG CCAACCTCAT TGGCGGTGTG GACATGGTCA CAGACGATGA CAGGAGGTGG 
AAGGCTGGGC TCTATGGGTT GCCTAAGCGG TCTGGAAAGC TGAAGGATCT GTCCAAGTTC 
GACGCCTCCT TTTTTGGGGT CCACCCCAAG CAGGCACACA CAATGGACCC GCAGCTCCGG 
CTGCTGCTGG AAGTCAGCTA TGAAGCTATT GTGGACGGAG GTATCAACCC GGCCTCACTC 
CGAGGAACAA ACACTGGTGT CTGGGTGGGT GTGAGTGGTT CCGAGGCGTC GGAGGCCCTG 
AGCAGAGATC CTGAGACTCT TCTGGGCTAC AGCATGGTGG GCTGCCAGAG AGCAATGATG 
GCCAACCGGC TCTCTTTCTT CTTCGACTTC AAAGGACCCA GCATTGCCCT GGACACAGCC 
TGCTCCTCTA GCCTACTGGC ACTACAGAAT GCCTATCAGG CTATCCGCAG TGGGGAGTGC 
CCTGCTGCCA TTGTGGGCGG GATCAACCTG CTGCTAAAGC CTAACACCTC TGTGCAGTTC 
ATGAAGCTAG GCATGCTCAG CCCCGATGGC ACCTGCAGAT CCTTTGATGA TTCAGGGAAC 
GGGTATTGCC GTGCTGAGGC TGTCGTGGCA GTTCTGCTGA CTAAGAAGTC CTTGGCTCGG 
CGAGTCTATG CCACTATTCT GAATGCCGGG ACGAACACAG ATGGCTGCAA GGAGCAAGGC 
GTGACATTCC CCTCTGGAGA AGCCCAGGAA CAACTCATCC GTTCTCTGTA TCAGCCGGGC 
GGTGTGGCCC CCGAGTCTCT TGAATATATT GAAGCCCATG GCACGGGCAC CAAGGTGGGG 
GACCCCCAGG AACTGAACGG CATTACTCGG TCCCTGTGTG CTTTCCGCCA GAGCCCTTTG 
TTAATTGGCT CCACCAAATC CAACATGGGA CACCCTGAGC CTGCCTCGGG GCTTGCAGCC 
CTGACCAAGG TGCTGTTATC CCTAGAAAAT GGGGTTTGGG CCCCCAACCT GCATTTCCAC 
AACCCCAACC CTGAAATCCC AGCACTTCTT GATGGGCGGC TGCAGGTGGT CGATAGGCCC 
CTGCCTGTTC GTGGTGGCAT CGTGGGCATC AACTCGTTTG GCTTCGGAGG TGCCAATGTT 
CACGTCATCC TCCAGCCCAA CACACAGCAG GCCCCAGCAC CTGCCCCACA TGCTGCCCTA 
CCGCATTTGC TGCATGCCAG TGGACGGACC ATGGAGGCAG TGCAGGGCCT GCTGGAACAG 
GGCCGCCAGC ACAGTCAGGA CTTGGCCTTT GTGAGCATGC TCAATGACAT TGCAGCAACC 
CCTACAGCAG CCATGCCCTT CAGAGGTTAC ACTGTGTTAG GTGTTGAGGG CCATGTCCAG 
GAAGTGCAGC AAGTGCCTGC CAGCCAGCGC CCACTCTGGT TCATCTGCTC AGGGATGGGC 
ACACAGTGGC GTGGAATGGG GCTGAGCCTT ATGCGCCTGG ACAGTTTCCG TGAGTCCATC 
CTGCGCTCTG ATGAGGCTCT GAAGCCCTTG GGAGTCAAAG TGTCAGACCT GCTGCTGAGC 
ACTGATGAGC ACACCTTTGA TGACATCGTG CATTCCTTTG TGAGCCTCAC CGCCATCCAG 
ATTGCCCTCA TCGACCTGCT GACGTCTATG GGGCTGAAAC CTGATGGCAT CATTGGGCAC 
TCCTTGGGAG AGGTTGCCTG TGGCTATGCA GATGGCTGTC TCTCCCAGAG AGAGGCTGTG 
CTTGCAGCCT ACTGGAGAGG CCAGTGCATT AAGGATGCCA ACCTTCCGGC TGGATCCATG 
GCAGCTGTTG GTTTGTCCTG GGAAGAATGT AAACAACGCT GCCCTCCTGG TGTGGTGCCT 
GCCTGCCACA ACTCTGAGGA CACTGTGACC ATCTCTGGAC CTCAGGCTGC AGTGAATGAA 
TTTGTGGAGC AGCTAAAGCA AGAGGGCGTG TTTGCCAAGG AGGTGCGAAC AGGTGGCCTG 
GCCTTCCACT CCTACTTCAT GGAAGGAATT GCCCCCACGC TGCTGCAGGC TCTCAAGAAG 
GTGATCCGGG AGCCACGGCC ACGCTCAGCA CGCTGGCTCA GCACCTCTAT CCCTGAGGCC 
CAGTGGCAGA GCAGCCTGGC CCGCACATCT TCTGCTGAGT ACAACGTCAA CAACCTGGTG 
AGCCCTGTGC TCTTCCAGGA AGCACTGTGG CACGTCCCCG AGCACGCCGT GGTGCTGGAG 
ATTGCACCCC ATGCACTGTT GCAGGCTGTC CTGAAGCGAG GCGTGAAGCC TAGCTGCACC 
ATCATCCCCT TGATGAAGAG GGACCATAAA GATAACTTGG AGTTCTTCCT CACCAACCTC 
GGCAAGGTGC ACCTCACAGG CATCGACATC AACCCTAATG CCTTGTTCCC ACCTGTGGAA 
TTCCCGGTTC CCCGAGGGAC TCCTCTCATC TCCCCTCACA TCAAGTGGGA CCACAGTCAG 
ACTTGGGATA TCCCAGTTGC TGAAGACTTC CCCAACGGTT CCAGCTCCTC CTCAGCTACA 
GTCTACAACA TTGACGCCAG TTCCGAGTCA TCTGACCACT ACCTGGTCGA CCACTGCATT 
GACGGCCGTG TCCTCTTCCC TGGCACTGGC TACCTGTACC TGGTGTGGAA GACACTGGCT 
CGAAGCCTGA GCTTGTCCCT AGAAGAGACC CCTGTGGTGT TTGAGAACGT GACATTTCAT 
CAGGCCACCA TCCTGCCCAG GACAGGAACC GTGCCTCTGG AGGTGCGGCT GCTAGAGGCC 
TCACATGCAT TTGAGGTGTC TGACAGTGGC AACCTGATAG TGAGCGGGAA AGTGTACCAG 
TGGGAAGACC CTGACTCCAA GTTATTCGAC CACCCAGAAG TCCCGATCCC CGCCGAGTCC 
GAGTCTGTCT CCCGCTTGAC GCAGGGAGAA GTATACAAGG AGCTGCGGCT ACGTGGCTAT 
GACTATGGCC CTCATTTCCA GGGCGTCTAT GAGGCCACCC TCGAAGGTGA GCAAGGCAAG 
CTGCTCTGGA AAGACAACTG GGTGACCTTC ATGGACACAA TGCTGCAGAT ATCCATCCTG 
GGCTTCAGCA AGCAGAGTCT GCAGCTACCC ACCCGTGTGA CTGCCATCTA TATTGACCCT 
GCAACCCACC TGCAGAAGGT GTACATGCTG GAGGGAGACA CTCAAGTGGC TGACGTGACC 
ACGAGCCGCT GTCTGGGCGT GACCGTCTCT GGTGGTGTCT ACATTTCGAG ACTACAGACA 
ACAGCAACCT CACGGCGGCA GCAGGAACAG CTGGTCCCCA CCCTGGAGAA GTTTGTCTTC 
ACACCCCATG TGGAGCCTGA GTGCCTGTCT GAGAGTGCTA TCCTGCAGAA AGAGCTGCAG 
CTGTGCAAGG GTCTGGCAAA GGCTCTGCAG ACCAAGGCCA CCCAGCAAGG GCTGAAGATG 
ACAGTGCCTG GGCTAGAGGA CCTTCCCCAG CATGGACTGC CTCGACTCTT GGCTGCTGCC 
TGCCAGCTGC AGCTCAACGG GAACCTGCAA CTGGAGTTAG GTGAGGTACT GGCTCGAGAG 
AGGCTCCTGC TGCCAGAAGA CCCTCTGATC AGTGGCCTCC TTAACTCCCA GGCCCTCAAG 
GCCTGCATAG ACACAGCCCT GGAGAACCTG TCTACTCTCA AGATGAAGGT GGTGGAGGTG 
CTGGCTGGAG AAGGCCACTT GTATTCCCAC ATCTCAGCAC TGCTCAACAC CCAGCCTATG 
CTGCAACTGG AGTATACAGC CACCGACCGG CACCCCCAGG CCCTGAAGGA TGTTCAGACC 
AAGCTGCAGC AGCATGATGT AGCACAGGGC CAGTGGGACC CTTCTGGTCC TGCTCCTACC 
AACCTGGGTG CTCTTGACCT TGTGGTGTGC AACTGTGCGT TAGCCACCCT GGGGGATCCA 
GCCCTGGCCC TGGACAACAT GGTAGCTGCC CTCAAGGATG GTGGTTTCCT GCTAATGCAC 
ACAGTGCTCA AAGGACATGC CCTTGGGGAA ACCCTGGCCT GCCTCCCTTC TGAGGTGCAG 
CCTGGGCCCA GCTTCTTAAG CCAGGAAGAG TGGGAGAGCC TGTTCTCAAG GAAGGCACTG 
CACCTGGTGG GCCTTAAAAA GTCATTCTAC GGTACTGCGC TGTTCCTGTG CCGCCGTCTC 
AGCCCACAGG ACAAGCCCAT CTTCCTGCCT GTGGAGGATA CTAGTTTCCA GTGGGTGGAC 
TCTCTGAAGA GCATTCTGGC CACATCCTCC TCCCAGCCTG TGTGGCTAAC AGCCATGAAC 
TGCCCCACCT CAGGTGTGGT AGGCTTGGTG AACTGTCTCC GAAAAGAGCC GGGTGGACAC 
CGGATTCGGT GTATCCTGCT GTCCAACCTC AGCAGCACAT CTCACGTCCC CAAGCTGGAC 
CCTGGCTCTT CAGAGCTACA GAAGGTGCTA GAGAGTGATC TGGTGATGAA CGTGTACAGG 
GACGGTGCCT GGGGTGCCTT CCGTCACTTC CAGTTAGAGC AGGACAAGCC CGAGGAGCAG 
ACAGCACATG CCTTTGTAAA CGTCCTTACC CGAGGGGACC TTGCCTCCAT CCGCTGGGTC 
TCTTCTCCCC TGAAACACAT GCAGCCGCCC TCGAGCTCAG GAGCACAGCT CTGCACTGTC 
TACTATGCCT CACTGAACTT CCGAGATATC ATGCTGGCCA CGGGCAAGCT GTCCCCTGAT 
GCCATTCCAG GTAAATGGGC CAGCCGGGAC TGCATGCTTG GCATGGAGTT CTCAGGCCGT 
GATAAGTGCG GCCGGCGTGT GATGGGGCTG GTACCCGCAG AAGGCCTGGC CACCTCAGTC 
CTGTTATCAC CCGACTTCCT CTGGGATGTA CCCTCTAGCT GGACCCTGGA GGAGGCGGCT 
TCTGTGCCTG TTGTCTACAC CACCGCCTAC TACTCCTTAG TAGTGCGTGG TCGTATTCAG 
CACGGGGAAA CTGTGCTCAT TCACTCGGGC TCCGGTGGTG TGGGCCAAGC GGCCATTTCC 
ATTGCCCTTA GCCTGGGCTG CCGAGTCTTC ACCACTGTGG GCTCCGCTGA GAAGCGAGCT 
TACCTCCAGG CCAGATTCCC TCAGCTGGAT GACACCAGCT TTGCTAACTC TCGAGACACA 
TCGTTTGAGC AGCATGTGTT ACTGCACACA GGTGGCAAAG GGGTGGACCT GGTCCTCAAC 
TCCCTGGCAG AAGAGAAGCT GCAGGCCAGT GTGCGGTGCT TGGCTCAGCA TGGCCGCTTC 
CTAGAGATCG GCAAATTTGA TCTTTCTAAC AACCACCCTC TGGGCATGGC CATCTTCTTG 
AAGAACGTCA CTTTCCATGG GATCCTGCTG GATGCACTTT TTGAGGGGGC CAACGACAGC 
TGGCGGGAGG TGGCAGAGCT GCTGAAGGCC GGCATCCGTG ATGGGGTTGT GAAGCCTCTC 
AAGTGTACAG TGTTTCCCAA GGCCCAGGTG GAGGACGCCT TCCGATACAT GGCTCAAGGA 
AAACATATTG GCAAAGTCCT TGTCCAGGTA CGGGAGGAGG AGCCCGAGGC TATGCTGCCA 
GGGGCTCAGC CCACCCTGAT TTCCGCCATC TCCAAGACCT TCTGCCCAGA GCATAAGAGT 
TACATCATCA CTGGTGGCCT AGGTGGCTTT GGCCTGGAAC TGGCCCGGTG GCTTGTGCTT 
CGTGGGGCCC AAAGGCTTGT ACTAACTTCC CGATCTGGAA TCCGCACAGG CTACCAAGCC 
AAGCACGTTC GGGAGTGGAG GCGCCAGGGC ATCCATGTGC TAGTGTCGAC AAGCAATGTC 
AGTTCACTGG AGGGGGCCCG TGCTCTCATC GCTGAAGCCA CAAAGCTTGG GCCCGTTGGA 
GGTGTCTTCA ACCTGGCCAT GGTTTTAAGG GATGCCATGC TGGAGAACCA GACTCCAGAA 
CTCTTCCAGG ATGTCAACAA GCCCAAGTAC AATGGCACCC TGAACCTTGA CAGGGCGACC 
CGGGAAGCCT GTCCTGAGCT GGACTACTTT GTGGCCTTCT CCTCTGTAAG CTGCGGGCGT 
GGTAATGCTG GCCAATCCAA CTATGGCTTC GCCAACTCTA CCATGGAGCG TATTTGCGAA 
CAGCGCCGGC ACGATGGCCT CCCAGGTCTT GCCGTGCAAT GGGGTGCCAT TGGTGACGTG 
GGCATTATCT TGGAAGCGAT GGGTACCAAT GACACAGTCG TTGGCGGCAC ACTGCCACAG 
CGCATCTCCT CCTGCATGGA GGTGCTGGAC CTCTTCCTGA ATCAGCCCCA CGCAGTCCTG 
AGCAGTTTTG TGCTGGTTGA GAAGAAAGCT GTGGCCCATG GTGATGGTGA AGCCCAGAGG 
GATCTGGTGA AAGCAGTGGC ACACATCCTA GGCATCCGCG ACCTCGCAGG GATTAACCTG 
GACAGCTCGC TGGCAGACCT CGGCCTGGAC TCGCTCATGG GTGTGGAAGT GCGCCAGATC 
CTGGAACGTG AACATGATCT GGTGCTACCC ATTCGTGAAG TACGGCAACT CACACTGCGG 
AAGCTTCAGG AAATGTCCTC CAAGGCTGGC TCAGACACTG AGTTGGCAGC CCCCAAGTCC 
AAGAATGATA CATCCCTGAA GCAGGCCCAG CTGAATCTGA GTATCCTGCT GGTGAACCCT 
GAGGGCCCTA CCTTAACACG ACTCAACTCA GTGCAGAGCT CTGAGCGGCC TCTGTTCCTG 
GTGCACCCCA TTGAAGGTTC CATCACTGTG TTCCACAGCC TGGCTGCCAA GCTCAGTGTG 
CCCACCTACG GTCTGCAGTG CACCCAAGCG GCCCCCCTGG ACAGCATTCC AAACCTGGCT 
GCCTACTACA TTGATTGCAT CAAGCAGGTG CAGCCTGAGG GGCCCCACCG AGTGGCTGGG 
TATTCTTTTG GAGCTTGTGT AGCCTTCGAG ATGTGCTCCC AGCTGCAGGC CCAGCAGGGC 
CCAGCCCCCG CCCACAACAA CCTCTTCTTG TTTGATGGCT CACACACCTA CGTATTGGCG 
TACACCCAGA GCTACCGGGC AAAGCTGACC CCAGGCTGTG AGGCTGAGGC TGAAGCTGAA 
GCCATATGCT TCTTCATTAA GCAGTTTGTT GATGCAGAGC ATAGCAAGGT GCTAGAGGCC 
CTGCTACCAC TGAAGAGCCT GGAGGACCGG GTTGCTGCTG CTGTGGACCT CATCACTAGA 
AGCCACCAGA GCCTGGACCG CCGTGACCTG AGCTTTGCTG CCGTGTCCTT CTACTACAAG 
CTTCGAGCCG CCGACCAGTA TAAACCCAAG GCCAAGTACC ACGGCAATGT GATCCTGCTG 
CGGGCCAAGA CAGGTGGCAC CTACGGCGAG GACTTGGGTG CCGATTACAA CCTGTCCCAG 
GTGTGTGATG GGAAGGTGTC TGTGCACATC ATTGAGGGTG ACCATCGTAC GCTGCTGGAG 
GGCAGGGGCC TGGAGTCTAT CATCAACATC ATCCACAGCT CCCTGGCTGA GCCTCGAGTG 
AGTGTACGGG AGGGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_059028.1
CDS	82..7599
Translation	MEEVVIAGMSGKLPESENLQEFWANLIGGVDMVTDDDRRWKAGLYGLPKRSGKLKDLSKFDASFFGVHPKQAHTMDPQLRLLLEVSYEAIVDGGINPASLRGTNTGVWVGVSGSEASEALSRDPETLLGYSMVGCQRAMMANRLSFFFDFKGPSIALDTACSSSLLALQNAYQAIRSGECPAAIVGGINLLLKPNTSVQFMKLGMLSPDGTCRSFDDSGNGYCRAEAVVAVLLTKKSLARRVYATILNAGTNTDGCKEQGVTFPSGEAQEQLIRSLYQPGGVAPESLEYIEAHGTGTKVGDPQELNGITRSLCAFRQSPLLIGSTKSNMGHPEPASGLAALTKVLLSLENGVWAPNLHFHNPNPEIPALLDGRLQVVDRPLPVRGGIVGINSFGFGGANVHVILQPNTQQAPAPAPHAALPHLLHASGRTMEAVQGLLEQGRQHSQDLAFVSMLNDIAATPTAAMPFRGYTVLGVEGHVQEVQQVPASQRPLWFICSGMGTQWRGMGLSLMRLDSFRESILRSDEALKPLGVKVSDLLLSTDEHTFDDIVHSFVSLTAIQIALIDLLTSMGLKPDGIIGHSLGEVACGYADGCLSQREAVLAAYWRGQCIKDANLPAGSMAAVGLSWEECKQRCPPGVVPACHNSEDTVTISGPQAAVNEFVEQLKQEGVFAKEVRTGGLAFHSYFMEGIAPTLLQALKKVIREPRPRSARWLSTSIPEAQWQSSLARTSSAEYNVNNLVSPVLFQEALWHVPEHAVVLEIAPHALLQAVLKRGVKPSCTIIPLMKRDHKDNLEFFLTNLGKVHLTGIDINPNALFPPVEFPVPRGTPLISPHIKWDHSQTWDIPVAEDFPNGSSSSSATVYNIDASSESSDHYLVDHCIDGRVLFPGTGYLYLVWKTLARSLSLSLEETPVVFENVTFHQATILPRTGTVPLEVRLLEASHAFEVSDSGNLIVSGKVYQWEDPDSKLFDHPEVPIPAESESVSRLTQGEVYKELRLRGYDYGPHFQGVYEATLEGEQGKLLWKDNWVTFMDTMLQISILGFSKQSLQLPTRVTAIYIDPATHLQKVYMLEGDTQVADVTTSRCLGVTVSGGVYISRLQTTATSRRQQEQLVPTLEKFVFTPHVEPECLSESAILQKELQLCKGLAKALQTKATQQGLKMTVPGLEDLPQHGLPRLLAAACQLQLNGNLQLELGEVLARERLLLPEDPLISGLLNSQALKACIDTALENLSTLKMKVVEVLAGEGHLYSHISALLNTQPMLQLEYTATDRHPQALKDVQTKLQQHDVAQGQWDPSGPAPTNLGALDLVVCNCALATLGDPALALDNMVAALKDGGFLLMHTVLKGHALGETLACLPSEVQPGPSFLSQEEWESLFSRKALHLVGLKKSFYGTALFLCRRLSPQDKPIFLPVEDTSFQWVDSLKSILATSSSQPVWLTAMNCPTSGVVGLVNCLRKEPGGHRIRCILLSNLSSTSHVPKLDPGSSELQKVLESDLVMNVYRDGAWGAFRHFQLEQDKPEEQTAHAFVNVLTRGDLASIRWVSSPLKHMQPPSSSGAQLCTVYYASLNFRDIMLATGKLSPDAIPGKWASRDCMLGMEFSGRDKCGRRVMGLVPAEGLATSVLLSPDFLWDVPSSWTLEEAASVPVVYTTAYYSLVVRGRIQHGETVLIHSGSGGVGQAAISIALSLGCRVFTTVGSAEKRAYLQARFPQLDDTSFANSRDTSFEQHVLLHTGGKGVDLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHPLGMAIFLKNVTFHGILLDALFEGANDSWREVAELLKAGIRDGVVKPLKCTVFPKAQVEDAFRYMAQGKHIGKVLVQVREEEPEAMLPGAQPTLISAISKTFCPEHKSYIITGGLGGFGLELARWLVLRGAQRLVLTSRSGIRTGYQAKHVREWRRQGIHVLVSTSNVSSLEGARALIAEATKLGPVGGVFNLAMVLRDAMLENQTPELFQDVNKPKYNGTLNLDRATREACPELDYFVAFSSVSCGRGNAGQSNYGFANSTMERICEQRRHDGLPGLAVQWGAIGDVGIILEAMGTNDTVVGGTLPQRISSCMEVLDLFLNQPHAVLSSFVLVEKKAVAHGDGEAQRDLVKAVAHILGIRDLAGINLDSSLADLGLDSLMGVEVRQILEREHDLVLPIREVRQLTLRKLQEMSSKAGSDTELAAPKSKNDTSLKQAQLNLSILLVNPEGPTLTRLNSVQSSERPLFLVHPIEGSITVFHSLAAKLSVPTYGLQCTQAAPLDSIPNLAAYYIDCIKQVQPEGPHRVAGYSFGACVAFEMCSQLQAQQGPAPAHNNLFLFDGSHTYVLAYTQSYRAKLTPGCEAEAEAEAICFFIKQFVDAEHSKVLEALLPLKSLEDRVAAAVDLITRSHQSLDRRDLSFAAVSFYYKLRAADQYKPKAKYHGNVILLRAKTGGTYGEDLGADYNLSQVCDGKVSVHIIEGDHRTLLEGRGLESIINIIHSSLAEPRVSVREG

Target ORF information:

RefSeq Version	NM_017332.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus fatty acid synthase (Fasn), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017332.1

ORF Insert Sequence:

ATGGAGGAGG TGGTGATAGC CGGTATGTCC GGGAAATTGC CCGAGTCAGA GAACCTGCAG 
GAGTTCTGGG CCAACCTCAT TGGCGGTGTG GACATGGTCA CAGACGATGA CAGGAGGTGG 
AAGGCTGGGC TCTATGGGTT GCCTAAGCGG TCTGGAAAGC TGAAGGATCT GTCCAAGTTC 
GACGCCTCCT TTTTTGGGGT CCACCCCAAG CAGGCACACA CAATGGACCC GCAGCTCCGG 
CTGCTGCTGG AAGTCAGCTA TGAAGCTATT GTGGACGGAG GTATCAACCC GGCCTCACTC 
CGAGGAACAA ACACTGGTGT CTGGGTGGGT GTGAGTGGTT CCGAGGCGTC GGAGGCCCTG 
AGCAGAGATC CTGAGACTCT TCTGGGCTAC AGCATGGTGG GCTGCCAGAG AGCAATGATG 
GCCAACCGGC TCTCTTTCTT CTTCGACTTC AAAGGACCCA GCATTGCCCT GGACACAGCC 
TGCTCCTCTA GCCTACTGGC ACTACAGAAT GCCTATCAGG CTATCCGCAG TGGGGAGTGC 
CCTGCTGCCA TTGTGGGCGG GATCAACCTG CTGCTAAAGC CTAACACCTC TGTGCAGTTC 
ATGAAGCTAG GCATGCTCAG CCCCGATGGC ACCTGCAGAT CCTTTGATGA TTCAGGGAAC 
GGGTATTGCC GTGCTGAGGC TGTCGTGGCA GTTCTGCTGA CTAAGAAGTC CTTGGCTCGG 
CGAGTCTATG CCACTATTCT GAATGCCGGG ACGAACACAG ATGGCTGCAA GGAGCAAGGC 
GTGACATTCC CCTCTGGAGA AGCCCAGGAA CAACTCATCC GTTCTCTGTA TCAGCCGGGC 
GGTGTGGCCC CCGAGTCTCT TGAATATATT GAAGCCCATG GCACGGGCAC CAAGGTGGGG 
GACCCCCAGG AACTGAACGG CATTACTCGG TCCCTGTGTG CTTTCCGCCA GAGCCCTTTG 
TTAATTGGCT CCACCAAATC CAACATGGGA CACCCTGAGC CTGCCTCGGG GCTTGCAGCC 
CTGACCAAGG TGCTGTTATC CCTAGAAAAT GGGGTTTGGG CCCCCAACCT GCATTTCCAC 
AACCCCAACC CTGAAATCCC AGCACTTCTT GATGGGCGGC TGCAGGTGGT CGATAGGCCC 
CTGCCTGTTC GTGGTGGCAT CGTGGGCATC AACTCGTTTG GCTTCGGAGG TGCCAATGTT 
CACGTCATCC TCCAGCCCAA CACACAGCAG GCCCCAGCAC CTGCCCCACA TGCTGCCCTA 
CCGCATTTGC TGCATGCCAG TGGACGGACC ATGGAGGCAG TGCAGGGCCT GCTGGAACAG 
GGCCGCCAGC ACAGTCAGGA CTTGGCCTTT GTGAGCATGC TCAATGACAT TGCAGCAACC 
CCTACAGCAG CCATGCCCTT CAGAGGTTAC ACTGTGTTAG GTGTTGAGGG CCATGTCCAG 
GAAGTGCAGC AAGTGCCTGC CAGCCAGCGC CCACTCTGGT TCATCTGCTC AGGGATGGGC 
ACACAGTGGC GTGGAATGGG GCTGAGCCTT ATGCGCCTGG ACAGTTTCCG TGAGTCCATC 
CTGCGCTCTG ATGAGGCTCT GAAGCCCTTG GGAGTCAAAG TGTCAGACCT GCTGCTGAGC 
ACTGATGAGC ACACCTTTGA TGACATCGTG CATTCCTTTG TGAGCCTCAC CGCCATCCAG 
ATTGCCCTCA TCGACCTGCT GACGTCTATG GGGCTGAAAC CTGATGGCAT CATTGGGCAC 
TCCTTGGGAG AGGTTGCCTG TGGCTATGCA GATGGCTGTC TCTCCCAGAG AGAGGCTGTG 
CTTGCAGCCT ACTGGAGAGG CCAGTGCATT AAGGATGCCA ACCTTCCGGC TGGATCCATG 
GCAGCTGTTG GTTTGTCCTG GGAAGAATGT AAACAACGCT GCCCTCCTGG TGTGGTGCCT 
GCCTGCCACA ACTCTGAGGA CACTGTGACC ATCTCTGGAC CTCAGGCTGC AGTGAATGAA 
TTTGTGGAGC AGCTAAAGCA AGAGGGCGTG TTTGCCAAGG AGGTGCGAAC AGGTGGCCTG 
GCCTTCCACT CCTACTTCAT GGAAGGAATT GCCCCCACGC TGCTGCAGGC TCTCAAGAAG 
GTGATCCGGG AGCCACGGCC ACGCTCAGCA CGCTGGCTCA GCACCTCTAT CCCTGAGGCC 
CAGTGGCAGA GCAGCCTGGC CCGCACATCT TCTGCTGAGT ACAACGTCAA CAACCTGGTG 
AGCCCTGTGC TCTTCCAGGA AGCACTGTGG CACGTCCCCG AGCACGCCGT GGTGCTGGAG 
ATTGCACCCC ATGCACTGTT GCAGGCTGTC CTGAAGCGAG GCGTGAAGCC TAGCTGCACC 
ATCATCCCCT TGATGAAGAG GGACCATAAA GATAACTTGG AGTTCTTCCT CACCAACCTC 
GGCAAGGTGC ACCTCACAGG CATCGACATC AACCCTAATG CCTTGTTCCC ACCTGTGGAA 
TTCCCGGTTC CCCGAGGGAC TCCTCTCATC TCCCCTCACA TCAAGTGGGA CCACAGTCAG 
ACTTGGGATA TCCCAGTTGC TGAAGACTTC CCCAACGGTT CCAGCTCCTC CTCAGCTACA 
GTCTACAACA TTGACGCCAG TTCCGAGTCA TCTGACCACT ACCTGGTCGA CCACTGCATT 
GACGGCCGTG TCCTCTTCCC TGGCACTGGC TACCTGTACC TGGTGTGGAA GACACTGGCT 
CGAAGCCTGA GCTTGTCCCT AGAAGAGACC CCTGTGGTGT TTGAGAACGT GACATTTCAT 
CAGGCCACCA TCCTGCCCAG GACAGGAACC GTGCCTCTGG AGGTGCGGCT GCTAGAGGCC 
TCACATGCAT TTGAGGTGTC TGACAGTGGC AACCTGATAG TGAGCGGGAA AGTGTACCAG 
TGGGAAGACC CTGACTCCAA GTTATTCGAC CACCCAGAAG TCCCGATCCC CGCCGAGTCC 
GAGTCTGTCT CCCGCTTGAC GCAGGGAGAA GTATACAAGG AGCTGCGGCT ACGTGGCTAT 
GACTATGGCC CTCATTTCCA GGGCGTCTAT GAGGCCACCC TCGAAGGTGA GCAAGGCAAG 
CTGCTCTGGA AAGACAACTG GGTGACCTTC ATGGACACAA TGCTGCAGAT ATCCATCCTG 
GGCTTCAGCA AGCAGAGTCT GCAGCTACCC ACCCGTGTGA CTGCCATCTA TATTGACCCT 
GCAACCCACC TGCAGAAGGT GTACATGCTG GAGGGAGACA CTCAAGTGGC TGACGTGACC 
ACGAGCCGCT GTCTGGGCGT GACCGTCTCT GGTGGTGTCT ACATTTCGAG ACTACAGACA 
ACAGCAACCT CACGGCGGCA GCAGGAACAG CTGGTCCCCA CCCTGGAGAA GTTTGTCTTC 
ACACCCCATG TGGAGCCTGA GTGCCTGTCT GAGAGTGCTA TCCTGCAGAA AGAGCTGCAG 
CTGTGCAAGG GTCTGGCAAA GGCTCTGCAG ACCAAGGCCA CCCAGCAAGG GCTGAAGATG 
ACAGTGCCTG GGCTAGAGGA CCTTCCCCAG CATGGACTGC CTCGACTCTT GGCTGCTGCC 
TGCCAGCTGC AGCTCAACGG GAACCTGCAA CTGGAGTTAG GTGAGGTACT GGCTCGAGAG 
AGGCTCCTGC TGCCAGAAGA CCCTCTGATC AGTGGCCTCC TTAACTCCCA GGCCCTCAAG 
GCCTGCATAG ACACAGCCCT GGAGAACCTG TCTACTCTCA AGATGAAGGT GGTGGAGGTG 
CTGGCTGGAG AAGGCCACTT GTATTCCCAC ATCTCAGCAC TGCTCAACAC CCAGCCTATG 
CTGCAACTGG AGTATACAGC CACCGACCGG CACCCCCAGG CCCTGAAGGA TGTTCAGACC 
AAGCTGCAGC AGCATGATGT AGCACAGGGC CAGTGGGACC CTTCTGGTCC TGCTCCTACC 
AACCTGGGTG CTCTTGACCT TGTGGTGTGC AACTGTGCGT TAGCCACCCT GGGGGATCCA 
GCCCTGGCCC TGGACAACAT GGTAGCTGCC CTCAAGGATG GTGGTTTCCT GCTAATGCAC 
ACAGTGCTCA AAGGACATGC CCTTGGGGAA ACCCTGGCCT GCCTCCCTTC TGAGGTGCAG 
CCTGGGCCCA GCTTCTTAAG CCAGGAAGAG TGGGAGAGCC TGTTCTCAAG GAAGGCACTG 
CACCTGGTGG GCCTTAAAAA GTCATTCTAC GGTACTGCGC TGTTCCTGTG CCGCCGTCTC 
AGCCCACAGG ACAAGCCCAT CTTCCTGCCT GTGGAGGATA CTAGTTTCCA GTGGGTGGAC 
TCTCTGAAGA GCATTCTGGC CACATCCTCC TCCCAGCCTG TGTGGCTAAC AGCCATGAAC 
TGCCCCACCT CAGGTGTGGT AGGCTTGGTG AACTGTCTCC GAAAAGAGCC GGGTGGACAC 
CGGATTCGGT GTATCCTGCT GTCCAACCTC AGCAGCACAT CTCACGTCCC CAAGCTGGAC 
CCTGGCTCTT CAGAGCTACA GAAGGTGCTA GAGAGTGATC TGGTGATGAA CGTGTACAGG 
GACGGTGCCT GGGGTGCCTT CCGTCACTTC CAGTTAGAGC AGGACAAGCC CGAGGAGCAG 
ACAGCACATG CCTTTGTAAA CGTCCTTACC CGAGGGGACC TTGCCTCCAT CCGCTGGGTC 
TCTTCTCCCC TGAAACACAT GCAGCCGCCC TCGAGCTCAG GAGCACAGCT CTGCACTGTC 
TACTATGCCT CACTGAACTT CCGAGATATC ATGCTGGCCA CGGGCAAGCT GTCCCCTGAT 
GCCATTCCAG GTAAATGGGC CAGCCGGGAC TGCATGCTTG GCATGGAGTT CTCAGGCCGT 
GATAAGTGCG GCCGGCGTGT GATGGGGCTG GTACCCGCAG AAGGCCTGGC CACCTCAGTC 
CTGTTATCAC CCGACTTCCT CTGGGATGTA CCCTCTAGCT GGACCCTGGA GGAGGCGGCT 
TCTGTGCCTG TTGTCTACAC CACCGCCTAC TACTCCTTAG TAGTGCGTGG TCGTATTCAG 
CACGGGGAAA CTGTGCTCAT TCACTCGGGC TCCGGTGGTG TGGGCCAAGC GGCCATTTCC 
ATTGCCCTTA GCCTGGGCTG CCGAGTCTTC ACCACTGTGG GCTCCGCTGA GAAGCGAGCT 
TACCTCCAGG CCAGATTCCC TCAGCTGGAT GACACCAGCT TTGCTAACTC TCGAGACACA 
TCGTTTGAGC AGCATGTGTT ACTGCACACA GGTGGCAAAG GGGTGGACCT GGTCCTCAAC 
TCCCTGGCAG AAGAGAAGCT GCAGGCCAGT GTGCGGTGCT TGGCTCAGCA TGGCCGCTTC 
CTAGAGATCG GCAAATTTGA TCTTTCTAAC AACCACCCTC TGGGCATGGC CATCTTCTTG 
AAGAACGTCA CTTTCCATGG GATCCTGCTG GATGCACTTT TTGAGGGGGC CAACGACAGC 
TGGCGGGAGG TGGCAGAGCT GCTGAAGGCC GGCATCCGTG ATGGGGTTGT GAAGCCTCTC 
AAGTGTACAG TGTTTCCCAA GGCCCAGGTG GAGGACGCCT TCCGATACAT GGCTCAAGGA 
AAACATATTG GCAAAGTCCT TGTCCAGGTA CGGGAGGAGG AGCCCGAGGC TATGCTGCCA 
GGGGCTCAGC CCACCCTGAT TTCCGCCATC TCCAAGACCT TCTGCCCAGA GCATAAGAGT 
TACATCATCA CTGGTGGCCT AGGTGGCTTT GGCCTGGAAC TGGCCCGGTG GCTTGTGCTT 
CGTGGGGCCC AAAGGCTTGT ACTAACTTCC CGATCTGGAA TCCGCACAGG CTACCAAGCC 
AAGCACGTTC GGGAGTGGAG GCGCCAGGGC ATCCATGTGC TAGTGTCGAC AAGCAATGTC 
AGTTCACTGG AGGGGGCCCG TGCTCTCATC GCTGAAGCCA CAAAGCTTGG GCCCGTTGGA 
GGTGTCTTCA ACCTGGCCAT GGTTTTAAGG GATGCCATGC TGGAGAACCA GACTCCAGAA 
CTCTTCCAGG ATGTCAACAA GCCCAAGTAC AATGGCACCC TGAACCTTGA CAGGGCGACC 
CGGGAAGCCT GTCCTGAGCT GGACTACTTT GTGGCCTTCT CCTCTGTAAG CTGCGGGCGT 
GGTAATGCTG GCCAATCCAA CTATGGCTTC GCCAACTCTA CCATGGAGCG TATTTGCGAA 
CAGCGCCGGC ACGATGGCCT CCCAGGTCTT GCCGTGCAAT GGGGTGCCAT TGGTGACGTG 
GGCATTATCT TGGAAGCGAT GGGTACCAAT GACACAGTCG TTGGCGGCAC ACTGCCACAG 
CGCATCTCCT CCTGCATGGA GGTGCTGGAC CTCTTCCTGA ATCAGCCCCA CGCAGTCCTG 
AGCAGTTTTG TGCTGGTTGA GAAGAAAGCT GTGGCCCATG GTGATGGTGA AGCCCAGAGG 
GATCTGGTGA AAGCAGTGGC ACACATCCTA GGCATCCGCG ACCTCGCAGG GATTAACCTG 
GACAGCTCGC TGGCAGACCT CGGCCTGGAC TCGCTCATGG GTGTGGAAGT GCGCCAGATC 
CTGGAACGTG AACATGATCT GGTGCTACCC ATTCGTGAAG TACGGCAACT CACACTGCGG 
AAGCTTCAGG AAATGTCCTC CAAGGCTGGC TCAGACACTG AGTTGGCAGC CCCCAAGTCC 
AAGAATGATA CATCCCTGAA GCAGGCCCAG CTGAATCTGA GTATCCTGCT GGTGAACCCT 
GAGGGCCCTA CCTTAACACG ACTCAACTCA GTGCAGAGCT CTGAGCGGCC TCTGTTCCTG 
GTGCACCCCA TTGAAGGTTC CATCACTGTG TTCCACAGCC TGGCTGCCAA GCTCAGTGTG 
CCCACCTACG GTCTGCAGTG CACCCAAGCG GCCCCCCTGG ACAGCATTCC AAACCTGGCT 
GCCTACTACA TTGATTGCAT CAAGCAGGTG CAGCCTGAGG GGCCCCACCG AGTGGCTGGG 
TATTCTTTTG GAGCTTGTGT AGCCTTCGAG ATGTGCTCCC AGCTGCAGGC CCAGCAGGGC 
CCAGCCCCCG CCCACAACAA CCTCTTCTTG TTTGATGGCT CACACACCTA CGTATTGGCG 
TACACCCAGA GCTACCGGGC AAAGCTGACC CCAGGCTGTG AGGCTGAGGC TGAAGCTGAA 
GCCATATGCT TCTTCATTAA GCAGTTTGTT GATGCAGAGC ATAGCAAGGT GCTAGAGGCC 
CTGCTACCAC TGAAGAGCCT GGAGGACCGG GTTGCTGCTG CTGTGGACCT CATCACTAGA 
AGCCACCAGA GCCTGGACCG CCGTGACCTG AGCTTTGCTG CCGTGTCCTT CTACTACAAG 
CTTCGAGCCG CCGACCAGTA TAAACCCAAG GCCAAGTACC ACGGCAATGT GATCCTGCTG 
CGGGCCAAGA CAGGTGGCAC CTACGGCGAG GACTTGGGTG CCGATTACAA CCTGTCCCAG 
GTGTGTGATG GGAAGGTGTC TGTGCACATC ATTGAGGGTG ACCATCGTAC GCTGCTGGAG 
GGCAGGGGCC TGGAGTCTAT CATCAACATC ATCCACAGCT CCCTGGCTGA GCCTCGAGTG 
AGTGTACGGG AGGGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Interleukin-15 derived from Guanylin-GC-C-expressing macrophages inhibits fatty acid synthase in adipocytes.
Peptides9914-19(2018 01)
Akieda-Asai S,Ida T,Miyazato M,Kangawa K,Date Y

Prenatal caloric restriction alters lipid metabolism but not hepatic Fasn gene expression and methylation profiles in rats.
BMC genetics18(1)78(2017 08)
Nowacka-Woszuk J,Madeja ZE,Chmurzynska A

Type of supplemented simple sugar, not merely calorie intake, determines adverse effects on metabolism and aortic function in female rats.
American journal of physiology. Heart and circulatory physiology312(2)H289-H304(2017 Feb)
Sangüesa G,Shaligram S,Akther F,Roglans N,Laguna JC,Rahimian R,Alegret M

Histone modifications in FASN modulated by sterol regulatory element-binding protein 1c and carbohydrate responsive-element binding protein under insulin stimulation are related to NAFLD.
Biochemical and biophysical research communications483(1)409-417(2017 01)
Du X,Cai C,Yao J,Zhou Y,Yu H,Shen W

Short term exendin-4 treatment reduces markers of metabolic disorders in female offspring of obese rat dams.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience4667-75(2015 Nov)
Chan YL,Saad S,Simar D,Oliver B,McGrath K,Reyk Dv,Bertrand PP,Gorrie C,Pollock C,Chen H

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Fasn cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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