Slc8b1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc8b1
Entrez Gene ID	498185
Full Name	solute carrier family 8 member B1
Synonyms	Slc24a6
General protein information	Preferred Names solute carrier family 8 member B1 Names mitochondrial sodium/calcium exchanger protein sodium/potassium/calcium exchanger 6, mitochondrial Na(+)/K(+)/Ca(2+)-exchange protein 6 sodium/calcium exchanger protein, mitochondrial solute carrier family 24 (sodium/lithium/calcium exchanger), member 6 solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 solute carrier family 24 member 6 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 12 Map Location: 12q16

mRNA and Protein(s)

mRNA	Protein	Name
NM_001017488.1	NP_001017488.1	mitochondrial sodium/calcium exchanger protein precursor
XM_017598443.1	XP_017453932.1	sodium/potassium/calcium exchanger 6, mitochondrial isoform X1

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	SLC24A6	XP_004934554.1
Drosophila melanogaster (fruit fly)	CG12376	NP_610405.3
Caenorhabditis elegans (roundworm)	ncx-7	NP_499147.3
Caenorhabditis elegans (roundworm)	ncx-10	NP_001256094.1
Caenorhabditis elegans (roundworm)	ncx-9	NP_504342.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007338	XP_308488.4
Homo sapiens (human)	SLC8B1	NP_079235.2
Drosophila melanogaster (fruit fly)	CG14743	NP_610408.2
Arabidopsis thaliana (thale cress)	CAX9	NP_566474.1
Xenopus tropicalis (tropical clawed frog)	slc8b1	NP_001017082.1
Oryza sativa (rice)	Os03g0180000	NP_001049159.1
Macaca mulatta (Rhesus monkey)	LOC714561	XP_001104394.1
Bos taurus (cattle)	SLC24A6	NP_001171067.1
Mus musculus (house mouse)	Slc8b1	NP_573484.2
Rattus norvegicus (Norway rat)	Slc24a6	NP_001017488.1
Danio rerio (zebrafish)	LOC560601	XP_689091.6
Neurospora crassa	NCU02826	XP_963783.2
Magnaporthe oryzae (rice blast fungus)	MGG_01638	XP_003714626.1
Pan troglodytes (chimpanzee)	SLC24A6	XP_001152982.1
Canis lupus familiaris (dog)	SLC8B1	XP_543406.3
Drosophila melanogaster (fruit fly)	CG5348	NP_611156.3
Caenorhabditis elegans (roundworm)	ncx-6	NP_499146.2
Caenorhabditis elegans (roundworm)	ncx-8	NP_504341.1
Arabidopsis thaliana (thale cress)	CCX4	NP_564650.1
Drosophila melanogaster (fruit fly)	CG14744	NP_001097232.2

Gene Ontology
Bibliography

Related articles in PubMed

Mitochondrial pore opening and loss of Ca
Purroy R, Britti E, Delaspre F, Tamarit J, Ros J
Biochimica et biophysica acta. Molecular basis of disease1864(2)618-631(2018 Feb)

The mitochondrial Na
Luongo TS, Lambert JP, Gross P, Nwokedi M, Lombardi AA, Shanmughapriya S, Carpenter AC, Kolmetzky D, Gao E, van Berlo JH, Tsai EJ, Molkentin JD, Chen X, Madesh M, Houser SR, Elrod JW
Nature545(7652)93-97(2017 05)

Mitochondria control store-operated Ca
Ben-Kasus Nissim T, Zhang X, Elazar A, Roy S, Stolwijk JA, Zhou Y, Motiani RK, Gueguinou M, Hempel N, Hershfinkel M, Gill DL, Trebak M, Sekler I
The EMBO journal36(6)797-815(2017 03)

Roles of the mitochondrial Na(+)-Ca(2+) exchanger, NCLX, in B lymphocyte chemotaxis.
Kim B, Takeuchi A, Hikida M, Matsuoka S
Scientific reports628378(2016 06)

NCLX protein, but not LETM1, mediates mitochondrial Ca2+ extrusion, thereby limiting Ca2+-induced NAD(P)H production and modulating matrix redox state.
De Marchi U, Santo-Domingo J, Castelbou C, Sekler I, Wiederkehr A, Demaurex N
The Journal of biological chemistry289(29)20377-85(2014 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Slc8b1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc8b1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05973	NM_001017488.1 Latest version!	Rattus norvegicus solute carrier family 8 member B1 (Slc8b1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa57886	XM_017598443.1 Latest version!	Rattus norvegicus solute carrier family 8 member B1 (Slc8b1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc8b1 ( NM_001017488.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001017488.1 Rattus norvegicus solute carrier family 8 member B1 (Slc8b1), mRNA.

Price & Availability↑

CloneID	ORa05973
Clone ID Related Accession (Same CDS sequence)	NM_001017488.1
Accession Version	NM_001017488.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1758bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Rattus norvegicus(Norway rat)
Product	mitochondrial sodium/calcium exchanger protein precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC079350.1. On Apr 29, 2005 this sequence version replaced XM_573402.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC079350.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCAGGCA GATGGCTGGA TCCGCTCTGG GCGCCTGGCT TCCTCTGTGT GGCTCTGATA 
CTGGAGACGG CATCTGGGGC CGGAGATCTA TCCACAAAAG CACATGGACA CATCCAGTTT 
TCAGCCAGAG GTGTCAACCA GACTGCCATG GCAGACTGCC GAGCTGTGTG TAGCCTGAAC 
ACATCTGACC GCTGTGACTT TGTCAAGAGG AATCCCGACT GCCACAGCGA GGGGGGCTAC 
CTGGACTACC TCAAGGGCAT CTTCTGCTAC TTCCCCCCCA ACCTCCTCCC TCTGGCCATC 
ACCCTCTATG TTTTCTGGCT CCTTTACCTC TTTCTGATCC TCGGAGTCAC CGCAGCCAAG 
TTCTTCTGCC CTAACTTGTC AGCCATCTCC ACCAGCCTCA AGCTCTCCCA CAACGTGGCA 
GGTGTCACCT TCCTGGCCTT TGGAAATGGC GCTCCAGACA TTTTCAGTGC TCTCGTGGCT 
TTCTCAGACC CTCGTACTGC TGGCCTGGCC ATTGGGGCTC TGTTTGGTGC AGGGGTGCTG 
GTCACTACTG TGGTGGCTGG TGGCATCACC ATCCTGCGTC CCTTCATGGC TGCCTCCAGG 
CCCTTCCTCA GGGACATCAC TTTCTATATG GTGGCCGTGT TCCTCACCTT CACCGCACTC 
TATCTCGGCA GGATCACACT GGTGTGGGCA CTGGGTTACC TGGGCCTCTA TGTCTTCTAT 
GTGGTCACGG TCATCATCTG CACTTGGGTC TACCAAAGGC AGCGGAGCAG GTCTTTGGTC 
CACTCCATAT CAGAGACACC AGAGCTACTG ACTGATTCAG AAGAGGATCA GATGTCTTCC 
AACACCAACA GCTATGACTA TGGAGAGGAG TACCGGCCTC TGCTGCTGGG TGAGGAGACC 
ACTGGGCAGA TCCTGCTCCA AGCCCTGAAT CCCTTGGACT ACAGGAAGTG GAGAACTCAG 
TCGATATCCT GCAAGCTCCT GAAAGTGGCC AAGTTGCCTG TGGAGTTCTT GTTGCTGCTC 
ACGGTACCCG TTGTGGACCC CGACAAGGAT GATCGGAACT GGAAACGGCC ACTCAACTGT 
CTGCAGCTGG TCATCAGCCC CCTGGTCCTG GTCCTGACCC TGCAGTCGGG GGTCTATGGC 
ATCTATGAGA TCGGTGGCCT CCTTCCTGTG TGGGCTGTAG TGGTGATCGT GGGCACAGCC 
CTGGCTTCAG TGACCTTCTT TGCCACATCT AACAGCGAAC CCCCTAGACT GCACTGGCTC 
TTTGCTTTCC TGGGTTTCCT GACCAGCGCC CTGTGGATCA ATGCAGCTGC CACGGAGGTG 
GTGAACATCT TGCGGTCCCT GGGCGTGGTC TTCCGTCTGA GCAACACCGT CCTAGGGCTG 
ACCCTCCTGG CCTGGGGGAA CAGCATTGGA GATGCGTTCT CAGATTTCAC GCTGGCCCGC 
CAGGGATACC CTCGGATGGC CTTCTCTGCC TGTTTTGGCG GCATCATCTT CAATATCCTG 
GTTGGTGTGG GACTGGGCTG CTTGCTACAA ATTGTCCGGA GCCATGCTTC CGAGGTGAAG 
CTGGAACCAG ACGGACTGCT GGTGTGGGTG CTGGCCAGTG CGCTGGGCCT CAGCCTGGTC 
TTCTCCCTGG TCTCGGTTCC GCTCCAGTGT TTCCAGCTCA GCAAGGCCTA CGGCCTCTGC 
CTCCTCCTCT TCTATATATG TTTCATTGTG GTGGTCCTCC TCACGGAGTT CGGGGTGATT 
CACTTGAAGG CTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001017488.1
CDS	133..1890
Translation	MAGRWLDPLWAPGFLCVALILETASGAGDLSTKAHGHIQFSARGVNQTAMADCRAVCSLNTSDRCDFVKRNPDCHSEGGYLDYLKGIFCYFPPNLLPLAITLYVFWLLYLFLILGVTAAKFFCPNLSAISTSLKLSHNVAGVTFLAFGNGAPDIFSALVAFSDPRTAGLAIGALFGAGVLVTTVVAGGITILRPFMAASRPFLRDITFYMVAVFLTFTALYLGRITLVWALGYLGLYVFYVVTVIICTWVYQRQRSRSLVHSISETPELLTDSEEDQMSSNTNSYDYGEEYRPLLLGEETTGQILLQALNPLDYRKWRTQSISCKLLKVAKLPVEFLLLLTVPVVDPDKDDRNWKRPLNCLQLVISPLVLVLTLQSGVYGIYEIGGLLPVWAVVVIVGTALASVTFFATSNSEPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLLQIVRSHASEVKLEPDGLLVWVLASALGLSLVFSLVSVPLQCFQLSKAYGLCLLLFYICFIVVVLLTEFGVIHLKAD

Target ORF information:

RefSeq Version	NM_001017488.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 8 member B1 (Slc8b1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001017488.1

ORF Insert Sequence:

ATGGCAGGCA GATGGCTGGA TCCGCTCTGG GCGCCTGGCT TCCTCTGTGT GGCTCTGATA 
CTGGAGACGG CATCTGGGGC CGGAGATCTA TCCACAAAAG CACATGGACA CATCCAGTTT 
TCAGCCAGAG GTGTCAACCA GACTGCCATG GCAGACTGCC GAGCTGTGTG TAGCCTGAAC 
ACATCTGACC GCTGTGACTT TGTCAAGAGG AATCCCGACT GCCACAGCGA GGGGGGCTAC 
CTGGACTACC TCAAGGGCAT CTTCTGCTAC TTCCCCCCCA ACCTCCTCCC TCTGGCCATC 
ACCCTCTATG TTTTCTGGCT CCTTTACCTC TTTCTGATCC TCGGAGTCAC CGCAGCCAAG 
TTCTTCTGCC CTAACTTGTC AGCCATCTCC ACCAGCCTCA AGCTCTCCCA CAACGTGGCA 
GGTGTCACCT TCCTGGCCTT TGGAAATGGC GCTCCAGACA TTTTCAGTGC TCTCGTGGCT 
TTCTCAGACC CTCGTACTGC TGGCCTGGCC ATTGGGGCTC TGTTTGGTGC AGGGGTGCTG 
GTCACTACTG TGGTGGCTGG TGGCATCACC ATCCTGCGTC CCTTCATGGC TGCCTCCAGG 
CCCTTCCTCA GGGACATCAC TTTCTATATG GTGGCCGTGT TCCTCACCTT CACCGCACTC 
TATCTCGGCA GGATCACACT GGTGTGGGCA CTGGGTTACC TGGGCCTCTA TGTCTTCTAT 
GTGGTCACGG TCATCATCTG CACTTGGGTC TACCAAAGGC AGCGGAGCAG GTCTTTGGTC 
CACTCCATAT CAGAGACACC AGAGCTACTG ACTGATTCAG AAGAGGATCA GATGTCTTCC 
AACACCAACA GCTATGACTA TGGAGAGGAG TACCGGCCTC TGCTGCTGGG TGAGGAGACC 
ACTGGGCAGA TCCTGCTCCA AGCCCTGAAT CCCTTGGACT ACAGGAAGTG GAGAACTCAG 
TCGATATCCT GCAAGCTCCT GAAAGTGGCC AAGTTGCCTG TGGAGTTCTT GTTGCTGCTC 
ACGGTACCCG TTGTGGACCC CGACAAGGAT GATCGGAACT GGAAACGGCC ACTCAACTGT 
CTGCAGCTGG TCATCAGCCC CCTGGTCCTG GTCCTGACCC TGCAGTCGGG GGTCTATGGC 
ATCTATGAGA TCGGTGGCCT CCTTCCTGTG TGGGCTGTAG TGGTGATCGT GGGCACAGCC 
CTGGCTTCAG TGACCTTCTT TGCCACATCT AACAGCGAAC CCCCTAGACT GCACTGGCTC 
TTTGCTTTCC TGGGTTTCCT GACCAGCGCC CTGTGGATCA ATGCAGCTGC CACGGAGGTG 
GTGAACATCT TGCGGTCCCT GGGCGTGGTC TTCCGTCTGA GCAACACCGT CCTAGGGCTG 
ACCCTCCTGG CCTGGGGGAA CAGCATTGGA GATGCGTTCT CAGATTTCAC GCTGGCCCGC 
CAGGGATACC CTCGGATGGC CTTCTCTGCC TGTTTTGGCG GCATCATCTT CAATATCCTG 
GTTGGTGTGG GACTGGGCTG CTTGCTACAA ATTGTCCGGA GCCATGCTTC CGAGGTGAAG 
CTGGAACCAG ACGGACTGCT GGTGTGGGTG CTGGCCAGTG CGCTGGGCCT CAGCCTGGTC 
TTCTCCCTGG TCTCGGTTCC GCTCCAGTGT TTCCAGCTCA GCAAGGCCTA CGGCCTCTGC 
CTCCTCCTCT TCTATATATG TTTCATTGTG GTGGTCCTCC TCACGGAGTT CGGGGTGATT 
CACTTGAAGG CTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc8b1 ( XM_017598443.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017453932.1 Rattus norvegicus solute carrier family 8 member B1 (Slc8b1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa57886
Clone ID Related Accession (Same CDS sequence)	XM_017598443.1
Accession Version	XM_017598443.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1764bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	sodium/potassium/calcium exchanger 6, mitochondrial isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGGCA GATGGCTGGA TCCGCTCTGG GCGCCTGGCT TCCTCTGTGT GGCTCTGATA 
CTGGAGACGG CATCTGGGGC CGGAGATCTA TCCACAAAAG CACATGGACA CATCCAGTTT 
TCAGCCAGAG GTGTCAACCA GACTGCCATG GCAGACTGCC GAGCTGTGTG TAGCCTGAAC 
ACATCTGACC GCTGTGACTT TGTCAAGAGG AATCCCGACT GCCACAGCGA GGGGGGCTAC 
CTGGACTACC TCAAGGGCAT CTTCTGCTAC TTCCCCCCCA ACCTCCTCCC TCTGGCCATC 
ACCCTCTATG TTTTCTGGCT CCTTTACCTC TTTCTGATCC TCGGAGTCAC CGCAGCCAAG 
TTCTTCTGCC CTAACTTGTC AGCCATCTCC ACCAGCCTCA AGCTCTCCCA CAACGTGGCA 
GGTGTCACCT TCCTGGCCTT TGGAAATGGC GCTCCAGACA TTTTCAGTGC TCTCGTGGCT 
TTCTCAGACC CTCGTACTGC TGGCCTGGCC ATTGGGGCTC TGTTTGGTGC AGGGGTGCTG 
GTCACTACTG TGGTGGCTGG TGGCATCACC ATCCTGCGTC CCTTCATGGC TGCCTCCAGG 
CCCTTCCTCA GGGACATCAC TTTCTATATG GTGGCCGTGT TCCTCACCTT CACCGCACTC 
TATCTCGGCA GGATCACACT GGTGTGGGCA CTGGGTTACC TGGGCCTCTA TGTCTTCTAT 
GTGGTCACGG TCATCATCTG CACTTGGGTC TACCAAAGGC AGCGGAGCAG GTCTTTGGTC 
CACTCCATAT CAGAGACACC AGAGCTACTG ACTGATTCAG AAGAGGATCA GATGTCTTCC 
AACACCAACA GCTATGACTA TGGAGAGGAG TACCGGCCTC TGCTGCTGGG TGAGGAGACC 
ACTGGGCAGA TCCTGCTCCA AGCCCTGAAT CCCTTGGACT ACAGGAAGTG GAGAACTCAG 
TCGATATCCT GCAAGCTCCT GAAAGTGGCC AAGTTGCCTG TGGAGTTCTT GTTGCTGCTC 
ACGGTACCCG TTGTGGACCC CGACAAGGAT GATCGGAACT GGAAACGGCC ACTCAACTGT 
CTGCAGCTGG TCATCAGCCC CCTGGTCCTG GTCCTGACCC TGCAGTCGGG GGTCTATGGC 
ATCTATGAGA TCGGTGGCCT CCTTCCTGTG TGGGCTGTAG TGGTGATCGT GGGCACAGCC 
CTGGCTTCAG TGACCTTCTT TGCCACATCT AACAGCGAAC CCCCTAGACT GCACTGGCTC 
TTTGCTTTCC TGGGTTTCCT GACCAGCGCC CTGTGGATCA ATGCAGCTGC CACGGAGGTG 
GTGAACATCT TGCGGTCCCT GGGCGTGGTC TTCCGTCTGA GCAACACCGT CCTAGGGCTG 
ACCCTCCTGG CCTGGGGGAA CAGCATTGGA GATGCGTTCT CAGATTTCAC GCTGGCCCGC 
CAGGGATACC CTCGGATGGC CTTCTCTGCC TGTTTTGGCG GCATCATCTT CAATATCCTG 
GTTGGTGTGG GACTGGGCTG CTTGCTACAA ATTGTCCGGA GCCATGCTTC CGAGGTGAAG 
GCTCTGGTTT GGCAAACACA CCAGAATTTT AAACAAGATT CTTTGGGGCC AGTGACTGTT 
ATACAAAAGT GCTGGGTACT GCACCCAGGA CTACCTGTCA GGCCGGGTAA AGAGAGGCGG 
GACAGACAGC AAGCACCAAA CACGGGCAGT CATTCACACA ACTGCCATTT CTTCGACTAC 
ACCCTTCAAA CACGGAAGGG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017453932.1
CDS	183..1946
Translation	MAGRWLDPLWAPGFLCVALILETASGAGDLSTKAHGHIQFSARGVNQTAMADCRAVCSLNTSDRCDFVKRNPDCHSEGGYLDYLKGIFCYFPPNLLPLAITLYVFWLLYLFLILGVTAAKFFCPNLSAISTSLKLSHNVAGVTFLAFGNGAPDIFSALVAFSDPRTAGLAIGALFGAGVLVTTVVAGGITILRPFMAASRPFLRDITFYMVAVFLTFTALYLGRITLVWALGYLGLYVFYVVTVIICTWVYQRQRSRSLVHSISETPELLTDSEEDQMSSNTNSYDYGEEYRPLLLGEETTGQILLQALNPLDYRKWRTQSISCKLLKVAKLPVEFLLLLTVPVVDPDKDDRNWKRPLNCLQLVISPLVLVLTLQSGVYGIYEIGGLLPVWAVVVIVGTALASVTFFATSNSEPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLLQIVRSHASEVKALVWQTHQNFKQDSLGPVTVIQKCWVLHPGLPVRPGKERRDRQQAPNTGSHSHNCHFFDYTLQTRKG

Target ORF information:

RefSeq Version	XM_017598443.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 8 member B1 (Slc8b1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017598443.1

ORF Insert Sequence:

ATGGCAGGCA GATGGCTGGA TCCGCTCTGG GCGCCTGGCT TCCTCTGTGT GGCTCTGATA 
CTGGAGACGG CATCTGGGGC CGGAGATCTA TCCACAAAAG CACATGGACA CATCCAGTTT 
TCAGCCAGAG GTGTCAACCA GACTGCCATG GCAGACTGCC GAGCTGTGTG TAGCCTGAAC 
ACATCTGACC GCTGTGACTT TGTCAAGAGG AATCCCGACT GCCACAGCGA GGGGGGCTAC 
CTGGACTACC TCAAGGGCAT CTTCTGCTAC TTCCCCCCCA ACCTCCTCCC TCTGGCCATC 
ACCCTCTATG TTTTCTGGCT CCTTTACCTC TTTCTGATCC TCGGAGTCAC CGCAGCCAAG 
TTCTTCTGCC CTAACTTGTC AGCCATCTCC ACCAGCCTCA AGCTCTCCCA CAACGTGGCA 
GGTGTCACCT TCCTGGCCTT TGGAAATGGC GCTCCAGACA TTTTCAGTGC TCTCGTGGCT 
TTCTCAGACC CTCGTACTGC TGGCCTGGCC ATTGGGGCTC TGTTTGGTGC AGGGGTGCTG 
GTCACTACTG TGGTGGCTGG TGGCATCACC ATCCTGCGTC CCTTCATGGC TGCCTCCAGG 
CCCTTCCTCA GGGACATCAC TTTCTATATG GTGGCCGTGT TCCTCACCTT CACCGCACTC 
TATCTCGGCA GGATCACACT GGTGTGGGCA CTGGGTTACC TGGGCCTCTA TGTCTTCTAT 
GTGGTCACGG TCATCATCTG CACTTGGGTC TACCAAAGGC AGCGGAGCAG GTCTTTGGTC 
CACTCCATAT CAGAGACACC AGAGCTACTG ACTGATTCAG AAGAGGATCA GATGTCTTCC 
AACACCAACA GCTATGACTA TGGAGAGGAG TACCGGCCTC TGCTGCTGGG TGAGGAGACC 
ACTGGGCAGA TCCTGCTCCA AGCCCTGAAT CCCTTGGACT ACAGGAAGTG GAGAACTCAG 
TCGATATCCT GCAAGCTCCT GAAAGTGGCC AAGTTGCCTG TGGAGTTCTT GTTGCTGCTC 
ACGGTACCCG TTGTGGACCC CGACAAGGAT GATCGGAACT GGAAACGGCC ACTCAACTGT 
CTGCAGCTGG TCATCAGCCC CCTGGTCCTG GTCCTGACCC TGCAGTCGGG GGTCTATGGC 
ATCTATGAGA TCGGTGGCCT CCTTCCTGTG TGGGCTGTAG TGGTGATCGT GGGCACAGCC 
CTGGCTTCAG TGACCTTCTT TGCCACATCT AACAGCGAAC CCCCTAGACT GCACTGGCTC 
TTTGCTTTCC TGGGTTTCCT GACCAGCGCC CTGTGGATCA ATGCAGCTGC CACGGAGGTG 
GTGAACATCT TGCGGTCCCT GGGCGTGGTC TTCCGTCTGA GCAACACCGT CCTAGGGCTG 
ACCCTCCTGG CCTGGGGGAA CAGCATTGGA GATGCGTTCT CAGATTTCAC GCTGGCCCGC 
CAGGGATACC CTCGGATGGC CTTCTCTGCC TGTTTTGGCG GCATCATCTT CAATATCCTG 
GTTGGTGTGG GACTGGGCTG CTTGCTACAA ATTGTCCGGA GCCATGCTTC CGAGGTGAAG 
GCTCTGGTTT GGCAAACACA CCAGAATTTT AAACAAGATT CTTTGGGGCC AGTGACTGTT 
ATACAAAAGT GCTGGGTACT GCACCCAGGA CTACCTGTCA GGCCGGGTAA AGAGAGGCGG 
GACAGACAGC AAGCACCAAA CACGGGCAGT CATTCACACA ACTGCCATTT CTTCGACTAC 
ACCCTTCAAA CACGGAAGGG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mitochondrial pore opening and loss of Ca
Biochimica et biophysica acta. Molecular basis of disease1864(2)618-631(2018 Feb)
Purroy R,Britti E,Delaspre F,Tamarit J,Ros J

The mitochondrial Na
Nature545(7652)93-97(2017 05)
Luongo TS,Lambert JP,Gross P,Nwokedi M,Lombardi AA,Shanmughapriya S,Carpenter AC,Kolmetzky D,Gao E,van Berlo JH,Tsai EJ,Molkentin JD,Chen X,Madesh M,Houser SR,Elrod JW

Mitochondria control store-operated Ca
The EMBO journal36(6)797-815(2017 03)
Ben-Kasus Nissim T,Zhang X,Elazar A,Roy S,Stolwijk JA,Zhou Y,Motiani RK,Gueguinou M,Hempel N,Hershfinkel M,Gill DL,Trebak M,Sekler I

Roles of the mitochondrial Na(+)-Ca(2+) exchanger, NCLX, in B lymphocyte chemotaxis.
Scientific reports628378(2016 06)
Kim B,Takeuchi A,Hikida M,Matsuoka S

NCLX protein, but not LETM1, mediates mitochondrial Ca2+ extrusion, thereby limiting Ca2+-induced NAD(P)H production and modulating matrix redox state.
The Journal of biological chemistry289(29)20377-85(2014 Jul)
De Marchi U,Santo-Domingo J,Castelbou C,Sekler I,Wiederkehr A,Demaurex N

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Slc8b1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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