Anapc11 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Anapc11
Entrez Gene ID	498030
Full Name	anaphase promoting complex subunit 11
Synonyms	RGD1561880
General protein information	Preferred Names anaphase promoting complex subunit 11 Names anaphase-promoting complex subunit 11
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q32.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_001126082.1	NP_001119554.1	anaphase-promoting complex subunit 11
XM_006247906.3	XP_006247968.1	anaphase-promoting complex subunit 11 isoform X1

Pathways from BioSystems

Homologies

Neurospora crassa	NCU11300	XP_001728250.1
Drosophila melanogaster (fruit fly)	lmgA	NP_001260262.1
Eremothecium gossypii	AGOS_AER016C	NP_984876.1
Macaca mulatta (Rhesus monkey)	ANAPC11	XP_001112301.1
Xenopus tropicalis (tropical clawed frog)	anapc11	NP_001011188.1
Kluyveromyces lactis	KLLA0E17711g	XP_454749.1
Schizosaccharomyces pombe (fission yeast)	apc11	NP_593423.1
Oryza sativa (rice)	Os03g0302700	NP_001049871.1
Magnaporthe oryzae (rice blast fungus)	MGG_04088	XP_003719750.1
Oryza sativa (rice)	Os07g0411101	NP_001175158.1
Mus musculus (house mouse)	Anapc11	NP_001033319.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008196	XP_317272.3
Homo sapiens (human)	ANAPC11	NP_057560.8
Pan troglodytes (chimpanzee)	ANAPC11	XP_001165452.1
Canis lupus familiaris (dog)	ANAPC11	XP_005624051.1
Rattus norvegicus (Norway rat)	Anapc11	NP_001119554.1
Bos taurus (cattle)	ANAPC11	NP_001107196.1
Danio rerio (zebrafish)	anapc11	NP_001091950.1
Saccharomyces cerevisiae (baker's yeast)	APC11	NP_010276.3
Arabidopsis thaliana (thale cress)	APC11	NP_001189819.1

Gene Ontology
Bibliography

Related articles in PubMed

APC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachment.
Mansfeld J, Collin P, Collins MO, Choudhary JS, Pines J
Nature cell biology13(10)1234-43(2011 Sep)

Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex.
Jin L, Williamson A, Banerjee S, Philipp I, Rape M
Cell133(4)653-65(2008 May)

Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C.
Dube P, Herzog F, Gieffers C, Sander B, Riedel D, Müller SA, Engel A, Peters JM, Stark H
Molecular cell20(6)867-79(2005 Dec)

APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex.
Tang Z, Li B, Bharadwaj R, Zhu H, Ozkan E, Hakala K, Deisenhofer J, Yu H
Molecular biology of the cell12(12)3839-51(2001 Dec)

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.
Ohta T, Michel JJ, Schottelius AJ, Xiong Y
Molecular cell3(4)535-41(1999 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Anapc11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Anapc11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01306	NM_001126082.1 Latest version!	Rattus norvegicus anaphase promoting complex subunit 11 (Anapc11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
ORa01306	XM_006247906.3 Latest version!	Rattus norvegicus anaphase promoting complex subunit 11 (Anapc11), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Anapc11 ( NM_001126082.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001119554.1 Rattus norvegicus anaphase promoting complex subunit 11 (Anapc11), mRNA.

Price & Availability↑

CloneID	ORa01306
Clone ID Related Accession (Same CDS sequence)	NM_001126082.1 , XM_006247906.3
Accession Version	NM_001126082.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 255bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1527350400000
Organism	Rattus norvegicus(Norway rat)
Product	anaphase-promoting complex subunit 11
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473948.1. On or before Apr 30, 2008 this sequence version replaced XM_573231.2, XM_001081824.1. ##Evidence-Data-START## CDS exon combination :: FQ228975.1, DV725102.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMD00052297, SAMEA2689604 [ECO:0000348] ##Evidence-Data-END##

ATGAAGGTGA AAATTAAGTG TTGGAATGGT GTGGCCACTT GGCTCTGGGT AGCCAATGAT 
GAGAACTGCG GCATCTGCAG GATGGCGTTC AATGGCTGCT GTCCAGACTG TAAGGTGCCT 
GGTGACGACT GTCCCCTGGT GTGGGGACAG TGCTCTCACT GCTTCCATAT GCACTGCATC 
CTCAAGTGGC TGAACGCACA GCAGGTGCAG CAGCACTGCC CCATGTGTCG ACAGGAGTGG 
AAGTTCAAAG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001119554.1
CDS	290..544
Translation	MKVKIKCWNGVATWLWVANDENCGICRMAFNGCCPDCKVPGDDCPLVWGQCSHCFHMHCILKWLNAQQVQQHCPMCRQEWKFKE

Target ORF information:

RefSeq Version	NM_001126082.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus anaphase promoting complex subunit 11 (Anapc11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001126082.1

ORF Insert Sequence:

ATGAAGGTGA AAATTAAGTG TTGGAATGGT GTGGCCACTT GGCTCTGGGT AGCCAATGAT 
GAGAACTGCG GCATCTGCAG GATGGCGTTC AATGGCTGCT GTCCAGACTG TAAGGTGCCT 
GGTGACGACT GTCCCCTGGT GTGGGGACAG TGCTCTCACT GCTTCCATAT GCACTGCATC 
CTCAAGTGGC TGAACGCACA GCAGGTGCAG CAGCACTGCC CCATGTGTCG ACAGGAGTGG 
AAGTTCAAAG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Anapc11 ( XM_006247906.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006247968.1 Rattus norvegicus anaphase promoting complex subunit 11 (Anapc11), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa01306
Clone ID Related Accession (Same CDS sequence)	NM_001126082.1 , XM_006247906.3
Accession Version	XM_006247906.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 255bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	anaphase-promoting complex subunit 11 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006247906.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGGTGA AAATTAAGTG TTGGAATGGT GTGGCCACTT GGCTCTGGGT AGCCAATGAT 
GAGAACTGCG GCATCTGCAG GATGGCGTTC AATGGCTGCT GTCCAGACTG TAAGGTGCCT 
GGTGACGACT GTCCCCTGGT GTGGGGACAG TGCTCTCACT GCTTCCATAT GCACTGCATC 
CTCAAGTGGC TGAACGCACA GCAGGTGCAG CAGCACTGCC CCATGTGTCG ACAGGAGTGG 
AAGTTCAAAG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006247968.1
CDS	234..488
Translation	MKVKIKCWNGVATWLWVANDENCGICRMAFNGCCPDCKVPGDDCPLVWGQCSHCFHMHCILKWLNAQQVQQHCPMCRQEWKFKE

Target ORF information:

RefSeq Version	XM_006247906.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus anaphase promoting complex subunit 11 (Anapc11), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006247906.3

ORF Insert Sequence:

ATGAAGGTGA AAATTAAGTG TTGGAATGGT GTGGCCACTT GGCTCTGGGT AGCCAATGAT 
GAGAACTGCG GCATCTGCAG GATGGCGTTC AATGGCTGCT GTCCAGACTG TAAGGTGCCT 
GGTGACGACT GTCCCCTGGT GTGGGGACAG TGCTCTCACT GCTTCCATAT GCACTGCATC 
CTCAAGTGGC TGAACGCACA GCAGGTGCAG CAGCACTGCC CCATGTGTCG ACAGGAGTGG 
AAGTTCAAAG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

APC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachment.
Nature cell biology13(10)1234-43(2011 Sep)
Mansfeld J,Collin P,Collins MO,Choudhary JS,Pines J

Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex.
Cell133(4)653-65(2008 May)
Jin L,Williamson A,Banerjee S,Philipp I,Rape M

Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C.
Molecular cell20(6)867-79(2005 Dec)
Dube P,Herzog F,Gieffers C,Sander B,Riedel D,Müller SA,Engel A,Peters JM,Stark H

APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex.
Molecular biology of the cell12(12)3839-51(2001 Dec)
Tang Z,Li B,Bharadwaj R,Zhu H,Ozkan E,Hakala K,Deisenhofer J,Yu H

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.
Molecular cell3(4)535-41(1999 Apr)
Ohta T,Michel JJ,Schottelius AJ,Xiong Y