Krt2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Krt2
Entrez Gene ID	406228
Full Name	keratin 2
Synonyms	CK 2e,Kb2
General protein information	Preferred Names keratin 2 Names keratin, type II cytoskeletal 2 epidermal CK-2e K2e cytokeratin-2e epithelial keratin-2e keratin 2, type II keratin-2 epidermis keratin-2e type II keratin Kb2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q36

mRNA and Protein(s)

mRNA	Protein	Name
NM_001008899.1	NP_001008899.1	keratin, type II cytoskeletal 2 epidermal
XM_006242436.2	XP_006242498.1	keratin, type II cytoskeletal 2 epidermal isoform X1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Keratins K2 and K10 are essential for the epidermal integrity of plantar skin.
Fischer H, Langbein L, Reichelt J, Buchberger M, Tschachler E, Eckhart L
Journal of dermatological science81(1)10-6(2016 Jan)

Loss of keratin K2 expression causes aberrant aggregation of K10, hyperkeratosis, and inflammation.
Fischer H, Langbein L, Reichelt J, Praetzel-Wunder S, Buchberger M, Ghannadan M, Tschachler E, Eckhart L
The Journal of investigative dermatology134(10)2579-2588(2014 Oct)

Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy.
Pieragostino D, Agnifili L, Fasanella V, D'Aguanno S, Mastropasqua R, Di Ilio C, Sacchetta P, Urbani A, Del Boccio P
Molecular bioSystems9(6)1108-16(2013 Jun)

Proteomic characterization of the human sperm nucleus.
de Mateo S, Castillo J, Estanyol JM, Ballescà JL, Oliva R
Proteomics11(13)2714-26(2011 Jul)

Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Krt2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Krt2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05831	NM_001008899.1 Latest version!	Rattus norvegicus keratin 2 (Krt2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
ORa30792	XM_006242436.2 Latest version!	Rattus norvegicus keratin 2 (Krt2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Krt2 ( NM_001008899.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001008899.1 Rattus norvegicus keratin 2 (Krt2), mRNA.

Price & Availability↑

CloneID	ORa05831
Clone ID Related Accession (Same CDS sequence)	NM_001008899.1
Accession Version	NM_001008899.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2058bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Rattus norvegicus(Norway rat)
Product	keratin, type II cytoskeletal 2 epidermal
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BK003983.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BK003983.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGAGTTGCC AGATCTCCTG CAAGTCCCGG AGAGGAGGAG GCGGAGGAGG AGGCGGTGGA 
TTCAGGGGCT TCAGTAGTGG CTCAGCTGTG GTCTCTGGAG GGAGCCGGAG ATCGACTTCC 
GGCTTCTCCT GCCTGAGCCG CCACGGTGGT GGCAGAGGAG GCTCTGGTGG AGGTGGCTTT 
GGCAGTCAGA GTCTTGTTGG CCTTGGAGGG TACAAGAGCA TCTCTAGTAG CGTGGCTGGC 
TACGGTGGTG GATTTGGTGG CAGAAGCTAC GGTGGCTTCG GAGGCGGCAG CGGCTTTGGA 
GGCAGCGGTG GCTTCGGAGG TGGCTCTGGC TTTGGAGGAG GCCGAGGATT TGGAGGTGGT 
AGCGGTTTCG GAGGCGGCAG CGGCTTTGGA GGTGGCAGCG GCTTTGGAGG TGGCAGCGGC 
TTCGGAGGCG GTGGATTTGG CGGAGGACGC TTTGGAGGTG GCCCTGGAGG TTTTGGGGGC 
CCTGGAGGAT TCCCTGGTGG AGGCATCCAT GAAGTGTCTG TCAATCAGAG CCTCTTGCAG 
CCTCTTGATG TTAAAGTGGA CCCAGAGATT CAGAACGTGA AGTCTCAGGA ACGGGAGCAG 
ATCAAAACCC TCAACAACAA ATTTGCCTCT TTCATTGACA CGGTGCGATT CCTGGAGCAG 
CAGAACCAGG TGTTGCACAC CAAATGGGAG CTGCTGCAGC AGCTGGATGT AGGCACCCGT 
ACCACCAACC TGGACCCCGT CTTCCAGGCC TACATTGGCA TACTCAAGAA GCAGGTGGAC 
AGGCTAACTG CGGAAAGGAA CTCACAGGAT TCAGAGCTGA ACAACATGCA GGATCTCGTG 
GAAGACTTTA AGAAGAAGTA CGAGGACGAG ATCAACAAGC GCACGTCTGC GGAGAATGAT 
TTCGTGACCA TCAAAAAGGA CGTGGACAGT TGCTACATGG ACAAGACAGA GCTGCAGGCC 
AAGATGGAGA TGCTGACACA GGAAGTCGAT TTCCTGAGAA CACTCTACGA CACGGAACTG 
TCCCAGCTAC AGCAGAATGT CACCGACACC AATGTCATCC TGTCCATGGA CAACAACCGG 
AACCTTGACC TGGACAGCAT CATTGCTGAA GTTCAGAGCC AATACGAGAT CATCGCCCAC 
AAGAGCAAGG CTGAGTCGGA GGAGCTGTAC CACAGCAAGG CAAATGAAGA ACTCCAGGTC 
ACCGCTGTGA AACATGGGGA CAGCTTGAAA GAGATCAAGA TGGAGATCAG CGAGTTGAAC 
CGAACAATCC AGAGGCTGCA AGGGGAGATA TCACATGTGA AGAAGCAGTG TAAAGGTGTG 
CAAGACTCCA TTGCAGATGC AGAGCAGCGT GGGGAGCACG CCATCAAAGA TGCCAGGGGC 
AAGCTCACTG ACCTGGAGGA GGCCCTGCAG CAGGGCCGAG AGAACCTGGC TCGGCTGCTG 
CGGGACTACC AGGAGCTCAT GAACGTCAAG CTGGCCCTGG ATGTGGAGAT CGCCACCTAC 
CGCAAGCTAC TGGAGGGGGA GGAGTGCAGG ATGTCTGGAG ACTTCAGCGA CAATGTGTCT 
GTCTCCGTGA CAAGCAGCAC CATCTCCTCA TCTGTGGCAT CTAAGGCTGG CTTTGGCTCC 
GGAGGTCAAA GTTCAGGAGG AAGAGGGTCT TACGGCGGAA GAGGAGGAGG AAGCACCTAT 
GGCTCTGGAG GCAGAAGCTC TGGTGTCAGA GGATCTGGAT CAGGATCTGG AGGAGGCGGA 
TACAGTTCTG GAGGAGGCTC CAGGGGAGGA TCTGGAGGAG GAGGATACAG CACTGGAGGA 
GGTTCTAGAG GAGGCTCCAG CTCTGGAGGG GGAGGATACA GCTCTGGAGG GGGCTCTAGA 
GGTGACTCCA GCTCTGGAGG AGGCTCCAGG GGAGGATCTG GAGGAGGCTC CAGGGGAGGA 
TCTGGAGGAG GAGGATACAG CTCTGGAGGA GGCTCTAGAG GAGGCTCCAG CTCTGGAGGG 
GCAGTGTCCG GCTCTGAAAG GGGTGGTTCT GGGTCAGGGG AAGGTTGCGG CTCCGGCGTG 
ACCTTCTCCT TTAGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001008899.1
CDS	1..2058
Translation	MSCQISCKSRRGGGGGGGGGFRGFSSGSAVVSGGSRRSTSGFSCLSRHGGGRGGSGGGGFGSQSLVGLGGYKSISSSVAGYGGGFGGRSYGGFGGGSGFGGSGGFGGGSGFGGGRGFGGGSGFGGGSGFGGGSGFGGGSGFGGGGFGGGRFGGGPGGFGGPGGFPGGGIHEVSVNQSLLQPLDVKVDPEIQNVKSQEREQIKTLNNKFASFIDTVRFLEQQNQVLHTKWELLQQLDVGTRTTNLDPVFQAYIGILKKQVDRLTAERNSQDSELNNMQDLVEDFKKKYEDEINKRTSAENDFVTIKKDVDSCYMDKTELQAKMEMLTQEVDFLRTLYDTELSQLQQNVTDTNVILSMDNNRNLDLDSIIAEVQSQYEIIAHKSKAESEELYHSKANEELQVTAVKHGDSLKEIKMEISELNRTIQRLQGEISHVKKQCKGVQDSIADAEQRGEHAIKDARGKLTDLEEALQQGRENLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDFSDNVSVSVTSSTISSSVASKAGFGSGGQSSGGRGSYGGRGGGSTYGSGGRSSGVRGSGSGSGGGGYSSGGGSRGGSGGGGYSTGGGSRGGSSSGGGGYSSGGGSRGDSSSGGGSRGGSGGGSRGGSGGGGYSSGGGSRGGSSSGGAVSGSERGGSGSGEGCGSGVTFSFR

Target ORF information:

RefSeq Version	NM_001008899.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus keratin 2 (Krt2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001008899.1

ORF Insert Sequence:

ATGAGTTGCC AGATCTCCTG CAAGTCCCGG AGAGGAGGAG GCGGAGGAGG AGGCGGTGGA 
TTCAGGGGCT TCAGTAGTGG CTCAGCTGTG GTCTCTGGAG GGAGCCGGAG ATCGACTTCC 
GGCTTCTCCT GCCTGAGCCG CCACGGTGGT GGCAGAGGAG GCTCTGGTGG AGGTGGCTTT 
GGCAGTCAGA GTCTTGTTGG CCTTGGAGGG TACAAGAGCA TCTCTAGTAG CGTGGCTGGC 
TACGGTGGTG GATTTGGTGG CAGAAGCTAC GGTGGCTTCG GAGGCGGCAG CGGCTTTGGA 
GGCAGCGGTG GCTTCGGAGG TGGCTCTGGC TTTGGAGGAG GCCGAGGATT TGGAGGTGGT 
AGCGGTTTCG GAGGCGGCAG CGGCTTTGGA GGTGGCAGCG GCTTTGGAGG TGGCAGCGGC 
TTCGGAGGCG GTGGATTTGG CGGAGGACGC TTTGGAGGTG GCCCTGGAGG TTTTGGGGGC 
CCTGGAGGAT TCCCTGGTGG AGGCATCCAT GAAGTGTCTG TCAATCAGAG CCTCTTGCAG 
CCTCTTGATG TTAAAGTGGA CCCAGAGATT CAGAACGTGA AGTCTCAGGA ACGGGAGCAG 
ATCAAAACCC TCAACAACAA ATTTGCCTCT TTCATTGACA CGGTGCGATT CCTGGAGCAG 
CAGAACCAGG TGTTGCACAC CAAATGGGAG CTGCTGCAGC AGCTGGATGT AGGCACCCGT 
ACCACCAACC TGGACCCCGT CTTCCAGGCC TACATTGGCA TACTCAAGAA GCAGGTGGAC 
AGGCTAACTG CGGAAAGGAA CTCACAGGAT TCAGAGCTGA ACAACATGCA GGATCTCGTG 
GAAGACTTTA AGAAGAAGTA CGAGGACGAG ATCAACAAGC GCACGTCTGC GGAGAATGAT 
TTCGTGACCA TCAAAAAGGA CGTGGACAGT TGCTACATGG ACAAGACAGA GCTGCAGGCC 
AAGATGGAGA TGCTGACACA GGAAGTCGAT TTCCTGAGAA CACTCTACGA CACGGAACTG 
TCCCAGCTAC AGCAGAATGT CACCGACACC AATGTCATCC TGTCCATGGA CAACAACCGG 
AACCTTGACC TGGACAGCAT CATTGCTGAA GTTCAGAGCC AATACGAGAT CATCGCCCAC 
AAGAGCAAGG CTGAGTCGGA GGAGCTGTAC CACAGCAAGG CAAATGAAGA ACTCCAGGTC 
ACCGCTGTGA AACATGGGGA CAGCTTGAAA GAGATCAAGA TGGAGATCAG CGAGTTGAAC 
CGAACAATCC AGAGGCTGCA AGGGGAGATA TCACATGTGA AGAAGCAGTG TAAAGGTGTG 
CAAGACTCCA TTGCAGATGC AGAGCAGCGT GGGGAGCACG CCATCAAAGA TGCCAGGGGC 
AAGCTCACTG ACCTGGAGGA GGCCCTGCAG CAGGGCCGAG AGAACCTGGC TCGGCTGCTG 
CGGGACTACC AGGAGCTCAT GAACGTCAAG CTGGCCCTGG ATGTGGAGAT CGCCACCTAC 
CGCAAGCTAC TGGAGGGGGA GGAGTGCAGG ATGTCTGGAG ACTTCAGCGA CAATGTGTCT 
GTCTCCGTGA CAAGCAGCAC CATCTCCTCA TCTGTGGCAT CTAAGGCTGG CTTTGGCTCC 
GGAGGTCAAA GTTCAGGAGG AAGAGGGTCT TACGGCGGAA GAGGAGGAGG AAGCACCTAT 
GGCTCTGGAG GCAGAAGCTC TGGTGTCAGA GGATCTGGAT CAGGATCTGG AGGAGGCGGA 
TACAGTTCTG GAGGAGGCTC CAGGGGAGGA TCTGGAGGAG GAGGATACAG CACTGGAGGA 
GGTTCTAGAG GAGGCTCCAG CTCTGGAGGG GGAGGATACA GCTCTGGAGG GGGCTCTAGA 
GGTGACTCCA GCTCTGGAGG AGGCTCCAGG GGAGGATCTG GAGGAGGCTC CAGGGGAGGA 
TCTGGAGGAG GAGGATACAG CTCTGGAGGA GGCTCTAGAG GAGGCTCCAG CTCTGGAGGG 
GCAGTGTCCG GCTCTGAAAG GGGTGGTTCT GGGTCAGGGG AAGGTTGCGG CTCCGGCGTG 
ACCTTCTCCT TTAGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Krt2 ( XM_006242436.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006242498.1 Rattus norvegicus keratin 2 (Krt2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa30792
Clone ID Related Accession (Same CDS sequence)	XM_006242436.2
Accession Version	XM_006242436.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2199bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	keratin, type II cytoskeletal 2 epidermal isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006242436.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCATAAGT GGGCCCACGC CCAAGCTCAC CAACACCTAG TCGGCAGGTA TATAAGGGAC 
CCTGTGAGTC TCCTACAGCA CAGTTTAGTC TCCAGCCTTG GATCTGCTCA GGAACGGTCA 
CTTGTCTTGC TGAGCAAAAC CATCATGAGT TGCCAGATCT CCTGCAAGTC CCGGAGAGGA 
GGAGGCGGAG GAGGAGGCGG TGGATTCAGG GGCTTCAGTA GTGGCTCAGC TGTGGTCTCT 
GGAGGGAGCC GGAGATCGAC TTCCGGCTTC TCCTGCCTGA GCCGCCACGG TGGTGGCAGA 
GGAGGCTCTG GTGGAGGTGG CTTTGGCAGT CAGAGTCTTG TTGGCCTTGG AGGGTACAAG 
AGCATCTCTA GTAGCGTGGC TGGCTACGGT GGTGGATTTG GTGGCAGAAG CTACGGTGGC 
TTCGGAGGCG GCAGCGGCTT TGGAGGCAGC GGTGGCTTCG GAGGTGGCTC TGGCTTTGGA 
GGAGGCCGAG GATTTGGAGG TGGTAGCGGT TTCGGAGGCG GCAGCGGCTT TGGAGGTGGC 
AGCGGCTTTG GAGGTGGCAG CGGCTTCGGA GGCGGTGGAT TTGGCGGAGG ACGCTTTGGA 
GGTGGCCCTG GAGGTTTTGG GGGCCCTGGA GGATTCCCTG GTGGAGGCAT CCATGAAGTG 
TCTGTCAATC AGAGCCTCTT GCAGCCTCTT GATGTTAAAG TGGACCCAGA GATTCAGAAC 
GTGAAGTCTC AGGAACGGGA GCAGATCAAA ACCCTCAACA ACAAATTTGC CTCTTTCATT 
GACACGGTGC GATTCCTGGA GCAGCAGAAC CAGGTGTTGC ACACCAAATG GGAGCTGCTG 
CAGCAGCTGG ATGTAGGCAC CCGTACCACC AACCTGGACC CCGTCTTCCA GGCCTACATT 
GGCATACTCA AGAAGCAGGT GGACAGGCTA ACTGCGGAAA GGAACTCACA GGATTCAGAG 
CTGAACAACA TGCAGGATCT CGTGGAAGAC TTTAAGAAGA AGTACGAGGA CGAGATCAAC 
AAGCGCACGT CTGCGGAGAA TGATTTCGTG ACCATCAAAA AGGACGTGGA CAGTTGCTAC 
ATGGACAAGA CAGAGCTGCA GGCCAAGATG GAGATGCTGA CACAGGAAGT CGATTTCCTG 
AGAACACTCT ACGACACGGA ACTGTCCCAG CTACAGCAGA ATGTCACCGA CACCAATGTC 
ATCCTGTCCA TGGACAACAA CCGGAACCTT GACCTGGACA GCATCATTGC TGAAGTTCAG 
AGCCAATACG AGATCATCGC CCACAAGAGC AAGGCTGAGT CGGAGGAGCT GTACCACAGC 
AAGTATGAAG AACTCCAGGT CACCGCTGTG AAACATGGGG ACAGCTTGAA AGAGATCAAG 
ATGGAGATCA GCGAGTTGAA CCGAACAATC CAGAGGCTGC AAGGGGAGAT ATCACATGTG 
AAGAAGCAGT GTAAAGGTGT GCAAGACTCC ATTGCAGATG CAGAGCAGCG TGGGGAGCAC 
GCCATCAAAG ATGCCAGGGG CAAGCTCACT GACCTGGAGG AGGCCCTGCA GCAGGGCCGA 
GAGAACCTGG CTCGGCTGCT GCGGGACTAC CAGGAGCTCA TGAACGTCAA GCTGGCCCTG 
GATGTGGAGA TCGCCACCTA CCGCAAGCTA CTGGAGGGGG AGGAGTGCAG GATGTCTGGA 
GACTTCAGCG ACAATGTGTC TGTCTCCGTG ACAAGCAGCA CCATCTCCTC ATCTGTGGCA 
TCTAAGGCTG GCTTTGGCTC CGGAGGTCAA AGTTCAGGAG GAAGAGGGTC TTACGGCGGA 
AGAGGAGGAG GAAGCACCTA TGGCTCTGGA GGCAGAAGCT CTGGTGTCAG AGGATCTGGA 
TCAGGATCTG GAGGAGGCGG ATACAGTTCT GGAGGAGGCT CCAGGGGAGG ATCTGGAGGA 
GGAGGATACA GCACTGGAGG AGGTTCTAGA GGAGGCTCCA GCTCTGGAGG GGGAGGATAC 
AGCTCTGGAG GGGGCTCTAG AGGTGACTCC AGCTCTGGAG GAGGCTCCAG GGGAGGATCT 
GGAGGAGGCT CCAGGGGAGG ATCTGGAGGA GGAGGATACA GCTCTGGAGG AGGCTCTAGA 
GGAGGCTCCA GCTCTGGAGG GGCAGTGTCC GGCTCTGAAA GGGGTGGTTC TGGGTCAGGG 
GAAGGTTGCG GCTCCGGCGT GACCTTCTCC TTTAGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006242498.1
CDS	361..2559
Translation	MHKWAHAQAHQHLVGRYIRDPVSLLQHSLVSSLGSAQERSLVLLSKTIMSCQISCKSRRGGGGGGGGGFRGFSSGSAVVSGGSRRSTSGFSCLSRHGGGRGGSGGGGFGSQSLVGLGGYKSISSSVAGYGGGFGGRSYGGFGGGSGFGGSGGFGGGSGFGGGRGFGGGSGFGGGSGFGGGSGFGGGSGFGGGGFGGGRFGGGPGGFGGPGGFPGGGIHEVSVNQSLLQPLDVKVDPEIQNVKSQEREQIKTLNNKFASFIDTVRFLEQQNQVLHTKWELLQQLDVGTRTTNLDPVFQAYIGILKKQVDRLTAERNSQDSELNNMQDLVEDFKKKYEDEINKRTSAENDFVTIKKDVDSCYMDKTELQAKMEMLTQEVDFLRTLYDTELSQLQQNVTDTNVILSMDNNRNLDLDSIIAEVQSQYEIIAHKSKAESEELYHSKYEELQVTAVKHGDSLKEIKMEISELNRTIQRLQGEISHVKKQCKGVQDSIADAEQRGEHAIKDARGKLTDLEEALQQGRENLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDFSDNVSVSVTSSTISSSVASKAGFGSGGQSSGGRGSYGGRGGGSTYGSGGRSSGVRGSGSGSGGGGYSSGGGSRGGSGGGGYSTGGGSRGGSSSGGGGYSSGGGSRGDSSSGGGSRGGSGGGSRGGSGGGGYSSGGGSRGGSSSGGAVSGSERGGSGSGEGCGSGVTFSFR

Target ORF information:

RefSeq Version	XM_006242436.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus keratin 2 (Krt2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006242436.2

ORF Insert Sequence:

ATGCATAAGT GGGCCCACGC CCAAGCTCAC CAACACCTAG TCGGCAGGTA TATAAGGGAC 
CCTGTGAGTC TCCTACAGCA CAGTTTAGTC TCCAGCCTTG GATCTGCTCA GGAACGGTCA 
CTTGTCTTGC TGAGCAAAAC CATCATGAGT TGCCAGATCT CCTGCAAGTC CCGGAGAGGA 
GGAGGCGGAG GAGGAGGCGG TGGATTCAGG GGCTTCAGTA GTGGCTCAGC TGTGGTCTCT 
GGAGGGAGCC GGAGATCGAC TTCCGGCTTC TCCTGCCTGA GCCGCCACGG TGGTGGCAGA 
GGAGGCTCTG GTGGAGGTGG CTTTGGCAGT CAGAGTCTTG TTGGCCTTGG AGGGTACAAG 
AGCATCTCTA GTAGCGTGGC TGGCTACGGT GGTGGATTTG GTGGCAGAAG CTACGGTGGC 
TTCGGAGGCG GCAGCGGCTT TGGAGGCAGC GGTGGCTTCG GAGGTGGCTC TGGCTTTGGA 
GGAGGCCGAG GATTTGGAGG TGGTAGCGGT TTCGGAGGCG GCAGCGGCTT TGGAGGTGGC 
AGCGGCTTTG GAGGTGGCAG CGGCTTCGGA GGCGGTGGAT TTGGCGGAGG ACGCTTTGGA 
GGTGGCCCTG GAGGTTTTGG GGGCCCTGGA GGATTCCCTG GTGGAGGCAT CCATGAAGTG 
TCTGTCAATC AGAGCCTCTT GCAGCCTCTT GATGTTAAAG TGGACCCAGA GATTCAGAAC 
GTGAAGTCTC AGGAACGGGA GCAGATCAAA ACCCTCAACA ACAAATTTGC CTCTTTCATT 
GACACGGTGC GATTCCTGGA GCAGCAGAAC CAGGTGTTGC ACACCAAATG GGAGCTGCTG 
CAGCAGCTGG ATGTAGGCAC CCGTACCACC AACCTGGACC CCGTCTTCCA GGCCTACATT 
GGCATACTCA AGAAGCAGGT GGACAGGCTA ACTGCGGAAA GGAACTCACA GGATTCAGAG 
CTGAACAACA TGCAGGATCT CGTGGAAGAC TTTAAGAAGA AGTACGAGGA CGAGATCAAC 
AAGCGCACGT CTGCGGAGAA TGATTTCGTG ACCATCAAAA AGGACGTGGA CAGTTGCTAC 
ATGGACAAGA CAGAGCTGCA GGCCAAGATG GAGATGCTGA CACAGGAAGT CGATTTCCTG 
AGAACACTCT ACGACACGGA ACTGTCCCAG CTACAGCAGA ATGTCACCGA CACCAATGTC 
ATCCTGTCCA TGGACAACAA CCGGAACCTT GACCTGGACA GCATCATTGC TGAAGTTCAG 
AGCCAATACG AGATCATCGC CCACAAGAGC AAGGCTGAGT CGGAGGAGCT GTACCACAGC 
AAGTATGAAG AACTCCAGGT CACCGCTGTG AAACATGGGG ACAGCTTGAA AGAGATCAAG 
ATGGAGATCA GCGAGTTGAA CCGAACAATC CAGAGGCTGC AAGGGGAGAT ATCACATGTG 
AAGAAGCAGT GTAAAGGTGT GCAAGACTCC ATTGCAGATG CAGAGCAGCG TGGGGAGCAC 
GCCATCAAAG ATGCCAGGGG CAAGCTCACT GACCTGGAGG AGGCCCTGCA GCAGGGCCGA 
GAGAACCTGG CTCGGCTGCT GCGGGACTAC CAGGAGCTCA TGAACGTCAA GCTGGCCCTG 
GATGTGGAGA TCGCCACCTA CCGCAAGCTA CTGGAGGGGG AGGAGTGCAG GATGTCTGGA 
GACTTCAGCG ACAATGTGTC TGTCTCCGTG ACAAGCAGCA CCATCTCCTC ATCTGTGGCA 
TCTAAGGCTG GCTTTGGCTC CGGAGGTCAA AGTTCAGGAG GAAGAGGGTC TTACGGCGGA 
AGAGGAGGAG GAAGCACCTA TGGCTCTGGA GGCAGAAGCT CTGGTGTCAG AGGATCTGGA 
TCAGGATCTG GAGGAGGCGG ATACAGTTCT GGAGGAGGCT CCAGGGGAGG ATCTGGAGGA 
GGAGGATACA GCACTGGAGG AGGTTCTAGA GGAGGCTCCA GCTCTGGAGG GGGAGGATAC 
AGCTCTGGAG GGGGCTCTAG AGGTGACTCC AGCTCTGGAG GAGGCTCCAG GGGAGGATCT 
GGAGGAGGCT CCAGGGGAGG ATCTGGAGGA GGAGGATACA GCTCTGGAGG AGGCTCTAGA 
GGAGGCTCCA GCTCTGGAGG GGCAGTGTCC GGCTCTGAAA GGGGTGGTTC TGGGTCAGGG 
GAAGGTTGCG GCTCCGGCGT GACCTTCTCC TTTAGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Keratins K2 and K10 are essential for the epidermal integrity of plantar skin.
Journal of dermatological science81(1)10-6(2016 Jan)
Fischer H,Langbein L,Reichelt J,Buchberger M,Tschachler E,Eckhart L

Loss of keratin K2 expression causes aberrant aggregation of K10, hyperkeratosis, and inflammation.
The Journal of investigative dermatology134(10)2579-2588(2014 Oct)
Fischer H,Langbein L,Reichelt J,Praetzel-Wunder S,Buchberger M,Ghannadan M,Tschachler E,Eckhart L

Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy.
Molecular bioSystems9(6)1108-16(2013 Jun)
Pieragostino D,Agnifili L,Fasanella V,D'Aguanno S,Mastropasqua R,Di Ilio C,Sacchetta P,Urbani A,Del Boccio P

Proteomic characterization of the human sperm nucleus.
Proteomics11(13)2714-26(2011 Jul)
de Mateo S,Castillo J,Estanyol JM,Ballescà JL,Oliva R

Defining the membrane proteome of NK cells.
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Ghosh D,Lippert D,Krokhin O,Cortens JP,Wilkins JA

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Krt2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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