Neil1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Neil1
Entrez Gene ID	367090
Full Name	nei-like DNA glycosylase 1
General protein information	Preferred Names nei-like DNA glycosylase 1 Names endonuclease 8-like 1 endonuclease VIII-like 1 nei endonuclease VIII-like 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q24

mRNA and Protein(s)

mRNA	Protein	Name
XM_006243135.3	XP_006243197.1	endonuclease 8-like 1 isoform X1
XM_006243134.3	XP_006243196.1	endonuclease 8-like 1 isoform X1
NM_001025754.1	NP_001020925.1	endonuclease 8-like 1
XM_006243136.3	XP_006243198.1	endonuclease 8-like 1 isoform X1

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	NEIL1	XP_002804926.1
Bos taurus (cattle)	NEIL1	NP_001014917.2
Mus musculus (house mouse)	Neil1	NP_082623.1
Rattus norvegicus (Norway rat)	Neil1	NP_001020925.1
Xenopus tropicalis (tropical clawed frog)	neil1	NP_001116270.1
Pan troglodytes (chimpanzee)	NEIL1	XP_003952754.1
Canis lupus familiaris (dog)	NEIL1	XP_854395.1
Danio rerio (zebrafish)	neil1	NP_956577.1
Homo sapiens (human)	NEIL1	NP_001243481.1
Gallus gallus (chicken)	NEIL1	NP_001074345.1

Gene Ontology
Bibliography

Related articles in PubMed

Induction of NEIL1 and NEIL2 DNA glycosylases in aniline-induced splenic toxicity.
Ma H, Wang J, Abdel-Rahman SZ, Hazra TK, Boor PJ, Khan MF
Toxicology and applied pharmacology251(1)1-7(2011 Feb)

The human Werner syndrome protein stimulates repair of oxidative DNA base damage by the DNA glycosylase NEIL1.
Das A, Boldogh I, Lee JW, Harrigan JA, Hegde ML, Piotrowski J, de Souza Pinto N, Ramos W, Greenberg MM, Hazra TK, Mitra S, Bohr VA
The Journal of biological chemistry282(36)26591-602(2007 Sep)

A back-up glycosylase in Nth1 knock-out mice is a functional Nei (endonuclease VIII) homologue.
Takao M, Kanno S, Kobayashi K, Zhang QM, Yonei S, van der Horst GT, Yasui A
The Journal of biological chemistry277(44)42205-13(2002 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Neil1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Neil1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa07659	NM_001025754.1 Latest version!	Rattus norvegicus nei-like DNA glycosylase 1 (Neil1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa31204	XM_006243135.3 Latest version!	Rattus norvegicus nei-like DNA glycosylase 1 (Neil1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa31204	XM_006243136.3 Latest version!	Rattus norvegicus nei-like DNA glycosylase 1 (Neil1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa31204	XM_006243134.3 Latest version!	Rattus norvegicus nei-like DNA glycosylase 1 (Neil1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Neil1 ( NM_001025754.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001020925.1 Rattus norvegicus nei-like DNA glycosylase 1 (Neil1), mRNA.

Price & Availability↑

CloneID	ORa07659
Clone ID Related Accession (Same CDS sequence)	NM_001025754.1
Accession Version	NM_001025754.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1164bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1527350400000
Organism	Rattus norvegicus(Norway rat)
Product	endonuclease 8-like 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC099125.1. On Jul 22, 2005 this sequence version replaced XM_345944.2. ##Evidence-Data-START## Transcript exon combination :: BC099125.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCCGGAGG GCCCAGAGCT GCACCTGGCC AGCCACTTTG TGAATGAGAT ATGTAAAGGG 
CTGGTATTCG GTGGGTGTGT GGAGAAGTCC TCTGTCAGCC GAAACCCGGA GGTGCCCTTT 
GAGAGCAGTG CCTACCACAT CTCAGCTTTA GCCCGAGGCA AGGAGCTGCG CTTGACATTG 
AGCCCCCTGC CTGGGTCCCA TCCCCCTCAG AAACCACTGT CCCTTGTCTT CCGCTTTGGT 
ATGTCTGGAT CCTTCCAGCT GGTACCCGCA GAAGCACTGC CGCGCCACGC CCATCTACGT 
TTCTATACGG CCCCACCTGC CCCCCGGCTT GCCCTTTGCT TCGTAGACAT CCGCCGCTTT 
GGCCACTGGG ACCCTGGAGG TGAATGGCAG CCAGGCCGCG GACCCTGTGT CTTGTTGGAG 
TATGAACGGT TCAGAGAGAA CGTGCTTCGG AACCTATCGG ACAAAGCCTT TGACCGGCCC 
ATCTGCGAGG CCTTGTTGGA CCAGAGGTTC TTCAATGGAA TCGGCAACTA TCTGCGGGCA 
GAGATCTTGT ATCGGCTGAA GATCCCCCCT TTTGAGAAGG CCCGTACAGT TCTAGAGGCC 
CTGCAACAGT GCCGGCTGAG CCCAGAGCTG ACCCTGAGCC AGAAGGTCAA GGCCAAACTG 
CAGAACCCAG ACCTGCTGGA ACTGTGTCAC TTGGTGCCCA AGGAAGTGGT TCAGCTGGGG 
GGCAAAGGCT ATGGGCCAGA GCGTGGAGAG GAAGATTTTG CTGCCTTTCG AGCCTGGCTT 
CGGTGCTATG CTGTGCCAGG CATGAGCTCC CTGAGAGACC GGCATGGCCG TACCATTTGG 
TTCCAGGGTG ATCCTGGACC CTTGGCACCC AAAGGGGGCA GATCCCGAAA AAAGAAGTCA 
CAGGAAACAC AGCTGGAGGC TGAGGACAGA AAAGAGGACC CTCCAAGCAA GTCCATTTCC 
AGGACTCAGA GGGCCAGGAA GCACTGTCCT AAGAATGTAC CTCAACAGTC TGAAGGGGCC 
AGCCTCCCAC AAAACCTGGA AACCCCTGCA GTCCCTGAGA AAGGAAAGAG AAGGGGGAGA 
CGGGCGAGCA CAGGCCGCCA CAGAGGACCA AAGAGTAAGC CTGATACTCA ACCCAGGGAG 
GCTGGGGAGA TTTCAGCCTC ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020925.1
CDS	114..1277
Translation	MPEGPELHLASHFVNEICKGLVFGGCVEKSSVSRNPEVPFESSAYHISALARGKELRLTLSPLPGSHPPQKPLSLVFRFGMSGSFQLVPAEALPRHAHLRFYTAPPAPRLALCFVDIRRFGHWDPGGEWQPGRGPCVLLEYERFRENVLRNLSDKAFDRPICEALLDQRFFNGIGNYLRAEILYRLKIPPFEKARTVLEALQQCRLSPELTLSQKVKAKLQNPDLLELCHLVPKEVVQLGGKGYGPERGEEDFAAFRAWLRCYAVPGMSSLRDRHGRTIWFQGDPGPLAPKGGRSRKKKSQETQLEAEDRKEDPPSKSISRTQRARKHCPKNVPQQSEGASLPQNLETPAVPEKGKRRGRRASTGRHRGPKSKPDTQPREAGEISAS

Target ORF information:

RefSeq Version	NM_001025754.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nei-like DNA glycosylase 1 (Neil1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025754.1

ORF Insert Sequence:

ATGCCGGAGG GCCCAGAGCT GCACCTGGCC AGCCACTTTG TGAATGAGAT ATGTAAAGGG 
CTGGTATTCG GTGGGTGTGT GGAGAAGTCC TCTGTCAGCC GAAACCCGGA GGTGCCCTTT 
GAGAGCAGTG CCTACCACAT CTCAGCTTTA GCCCGAGGCA AGGAGCTGCG CTTGACATTG 
AGCCCCCTGC CTGGGTCCCA TCCCCCTCAG AAACCACTGT CCCTTGTCTT CCGCTTTGGT 
ATGTCTGGAT CCTTCCAGCT GGTACCCGCA GAAGCACTGC CGCGCCACGC CCATCTACGT 
TTCTATACGG CCCCACCTGC CCCCCGGCTT GCCCTTTGCT TCGTAGACAT CCGCCGCTTT 
GGCCACTGGG ACCCTGGAGG TGAATGGCAG CCAGGCCGCG GACCCTGTGT CTTGTTGGAG 
TATGAACGGT TCAGAGAGAA CGTGCTTCGG AACCTATCGG ACAAAGCCTT TGACCGGCCC 
ATCTGCGAGG CCTTGTTGGA CCAGAGGTTC TTCAATGGAA TCGGCAACTA TCTGCGGGCA 
GAGATCTTGT ATCGGCTGAA GATCCCCCCT TTTGAGAAGG CCCGTACAGT TCTAGAGGCC 
CTGCAACAGT GCCGGCTGAG CCCAGAGCTG ACCCTGAGCC AGAAGGTCAA GGCCAAACTG 
CAGAACCCAG ACCTGCTGGA ACTGTGTCAC TTGGTGCCCA AGGAAGTGGT TCAGCTGGGG 
GGCAAAGGCT ATGGGCCAGA GCGTGGAGAG GAAGATTTTG CTGCCTTTCG AGCCTGGCTT 
CGGTGCTATG CTGTGCCAGG CATGAGCTCC CTGAGAGACC GGCATGGCCG TACCATTTGG 
TTCCAGGGTG ATCCTGGACC CTTGGCACCC AAAGGGGGCA GATCCCGAAA AAAGAAGTCA 
CAGGAAACAC AGCTGGAGGC TGAGGACAGA AAAGAGGACC CTCCAAGCAA GTCCATTTCC 
AGGACTCAGA GGGCCAGGAA GCACTGTCCT AAGAATGTAC CTCAACAGTC TGAAGGGGCC 
AGCCTCCCAC AAAACCTGGA AACCCCTGCA GTCCCTGAGA AAGGAAAGAG AAGGGGGAGA 
CGGGCGAGCA CAGGCCGCCA CAGAGGACCA AAGAGTAAGC CTGATACTCA ACCCAGGGAG 
GCTGGGGAGA TTTCAGCCTC ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Neil1 ( XM_006243135.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006243197.1 Rattus norvegicus nei-like DNA glycosylase 1 (Neil1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa31204
Clone ID Related Accession (Same CDS sequence)	XM_006243135.3 , XM_006243134.3 , XM_006243136.3
Accession Version	XM_006243135.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1170bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	endonuclease 8-like 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006243135.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGGAGG GCCCAGAGCT GCACCTGGCC AGCCACTTTG TGAATGAGAT ATGTAAAGGG 
CTGGTATTCG GTGGGTGTGT GGAGAAGTCC TCTGTCAGCC GAAACCCGGA GGTGCCCTTT 
GAGAGCAGTG CCTACCACAT CTCAGCTTTA GCCCGAGGCA AGGAGCTGCG CTTGACATTG 
AGCCCCCTGC CTGGGTCCCA TCCCCCTCAG AAACCACTGT CCCTTGTCTT CCGCTTTGGT 
ATGTCTGGAT CCTTCCAGCT GGTACCCGCA GAAGCACTGC CGCGCCACGC CCATCTACGT 
TTCTATACGG CCCCACCTGC CCCCCGGCTT GCCCTTTGCT TCGTAGACAT CCGCCGCTTT 
GGCCACTGGG ACCCTGGAGG TGAATGGCAG CCAGGCCGCG GACCCTGTGT CTTGTTGGAG 
TATGAACGGT TCAGAGAGAA CGTGCTTCGG AACCTATCGG ACAAAGCCTT TGACCGGCCC 
ATCTGCGAGG CCTTGTTGGA CCAGAGGTTC TTCAATGGAA TCGGCAACTA TCTGCGGGCA 
GAGATCTTGT ATCGGCTGAA GATCCCCCCT TTTGAGAAGG CCCGTACAGT TCTAGAGGCC 
CTGCAACAGT GCCGGCTGAG CCCAGAGCTG ACCCTGAGCC AGAAGGTCAA GGCCAAACTG 
CAGAACCCAG ACCTGCTGGA ACTGTGTCAC TTGGTGCCCA AGGAAGTGGT TCAGCTGGGG 
GGCAAAGGCT ATGGGCCAGA GCGTGGAGAG GAAGATTTTG CTGCCTTTCG AGCCTGGCTT 
CGGTGCTATG CTGTGCCAGG CATGAGCTCC CTGAGAGACC GGCATGGCCG TACCATTTGG 
TTCCAGGGTG ATCCTGGACC CTTGGCACCC AAAGGGGGCA GATCCCGAAA AAAGAAGTCA 
CAGGAAACAC AGCTGGAGGC TGAGGACAGA AAAGAGGACC CTCCAAGCAA GTCCATTTCC 
AGGACTCAGA GGGCCAGGAA GCACTGTCCT AAGAATGTAC CTCAACAGTC TGAAGGGGCC 
AGCCTCCCAC AAAACCTGGA AACCCCTGCA GTCCCTGAGA AAGGAAAGAG AAGGGGGAGA 
CGGGCGAGCA CAGGTGAGCT GTTTGCAGCA TCCTCCTTGA GCTGGGAAGA AAGAGCCAGG 
GAGTGGCTCA TCAGGGAGGA TGGGAGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006243197.1
CDS	1035..2204
Translation	MPEGPELHLASHFVNEICKGLVFGGCVEKSSVSRNPEVPFESSAYHISALARGKELRLTLSPLPGSHPPQKPLSLVFRFGMSGSFQLVPAEALPRHAHLRFYTAPPAPRLALCFVDIRRFGHWDPGGEWQPGRGPCVLLEYERFRENVLRNLSDKAFDRPICEALLDQRFFNGIGNYLRAEILYRLKIPPFEKARTVLEALQQCRLSPELTLSQKVKAKLQNPDLLELCHLVPKEVVQLGGKGYGPERGEEDFAAFRAWLRCYAVPGMSSLRDRHGRTIWFQGDPGPLAPKGGRSRKKKSQETQLEAEDRKEDPPSKSISRTQRARKHCPKNVPQQSEGASLPQNLETPAVPEKGKRRGRRASTGELFAASSLSWEERAREWLIREDGR

Target ORF information:

RefSeq Version	XM_006243135.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nei-like DNA glycosylase 1 (Neil1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006243135.3

ORF Insert Sequence:

ATGCCGGAGG GCCCAGAGCT GCACCTGGCC AGCCACTTTG TGAATGAGAT ATGTAAAGGG 
CTGGTATTCG GTGGGTGTGT GGAGAAGTCC TCTGTCAGCC GAAACCCGGA GGTGCCCTTT 
GAGAGCAGTG CCTACCACAT CTCAGCTTTA GCCCGAGGCA AGGAGCTGCG CTTGACATTG 
AGCCCCCTGC CTGGGTCCCA TCCCCCTCAG AAACCACTGT CCCTTGTCTT CCGCTTTGGT 
ATGTCTGGAT CCTTCCAGCT GGTACCCGCA GAAGCACTGC CGCGCCACGC CCATCTACGT 
TTCTATACGG CCCCACCTGC CCCCCGGCTT GCCCTTTGCT TCGTAGACAT CCGCCGCTTT 
GGCCACTGGG ACCCTGGAGG TGAATGGCAG CCAGGCCGCG GACCCTGTGT CTTGTTGGAG 
TATGAACGGT TCAGAGAGAA CGTGCTTCGG AACCTATCGG ACAAAGCCTT TGACCGGCCC 
ATCTGCGAGG CCTTGTTGGA CCAGAGGTTC TTCAATGGAA TCGGCAACTA TCTGCGGGCA 
GAGATCTTGT ATCGGCTGAA GATCCCCCCT TTTGAGAAGG CCCGTACAGT TCTAGAGGCC 
CTGCAACAGT GCCGGCTGAG CCCAGAGCTG ACCCTGAGCC AGAAGGTCAA GGCCAAACTG 
CAGAACCCAG ACCTGCTGGA ACTGTGTCAC TTGGTGCCCA AGGAAGTGGT TCAGCTGGGG 
GGCAAAGGCT ATGGGCCAGA GCGTGGAGAG GAAGATTTTG CTGCCTTTCG AGCCTGGCTT 
CGGTGCTATG CTGTGCCAGG CATGAGCTCC CTGAGAGACC GGCATGGCCG TACCATTTGG 
TTCCAGGGTG ATCCTGGACC CTTGGCACCC AAAGGGGGCA GATCCCGAAA AAAGAAGTCA 
CAGGAAACAC AGCTGGAGGC TGAGGACAGA AAAGAGGACC CTCCAAGCAA GTCCATTTCC 
AGGACTCAGA GGGCCAGGAA GCACTGTCCT AAGAATGTAC CTCAACAGTC TGAAGGGGCC 
AGCCTCCCAC AAAACCTGGA AACCCCTGCA GTCCCTGAGA AAGGAAAGAG AAGGGGGAGA 
CGGGCGAGCA CAGGTGAGCT GTTTGCAGCA TCCTCCTTGA GCTGGGAAGA AAGAGCCAGG 
GAGTGGCTCA TCAGGGAGGA TGGGAGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Neil1 ( XM_006243134.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006243196.1 Rattus norvegicus nei-like DNA glycosylase 1 (Neil1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa31204
Clone ID Related Accession (Same CDS sequence)	XM_006243135.3 , XM_006243134.3 , XM_006243136.3
Accession Version	XM_006243134.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1170bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	endonuclease 8-like 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006243134.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGGAGG GCCCAGAGCT GCACCTGGCC AGCCACTTTG TGAATGAGAT ATGTAAAGGG 
CTGGTATTCG GTGGGTGTGT GGAGAAGTCC TCTGTCAGCC GAAACCCGGA GGTGCCCTTT 
GAGAGCAGTG CCTACCACAT CTCAGCTTTA GCCCGAGGCA AGGAGCTGCG CTTGACATTG 
AGCCCCCTGC CTGGGTCCCA TCCCCCTCAG AAACCACTGT CCCTTGTCTT CCGCTTTGGT 
ATGTCTGGAT CCTTCCAGCT GGTACCCGCA GAAGCACTGC CGCGCCACGC CCATCTACGT 
TTCTATACGG CCCCACCTGC CCCCCGGCTT GCCCTTTGCT TCGTAGACAT CCGCCGCTTT 
GGCCACTGGG ACCCTGGAGG TGAATGGCAG CCAGGCCGCG GACCCTGTGT CTTGTTGGAG 
TATGAACGGT TCAGAGAGAA CGTGCTTCGG AACCTATCGG ACAAAGCCTT TGACCGGCCC 
ATCTGCGAGG CCTTGTTGGA CCAGAGGTTC TTCAATGGAA TCGGCAACTA TCTGCGGGCA 
GAGATCTTGT ATCGGCTGAA GATCCCCCCT TTTGAGAAGG CCCGTACAGT TCTAGAGGCC 
CTGCAACAGT GCCGGCTGAG CCCAGAGCTG ACCCTGAGCC AGAAGGTCAA GGCCAAACTG 
CAGAACCCAG ACCTGCTGGA ACTGTGTCAC TTGGTGCCCA AGGAAGTGGT TCAGCTGGGG 
GGCAAAGGCT ATGGGCCAGA GCGTGGAGAG GAAGATTTTG CTGCCTTTCG AGCCTGGCTT 
CGGTGCTATG CTGTGCCAGG CATGAGCTCC CTGAGAGACC GGCATGGCCG TACCATTTGG 
TTCCAGGGTG ATCCTGGACC CTTGGCACCC AAAGGGGGCA GATCCCGAAA AAAGAAGTCA 
CAGGAAACAC AGCTGGAGGC TGAGGACAGA AAAGAGGACC CTCCAAGCAA GTCCATTTCC 
AGGACTCAGA GGGCCAGGAA GCACTGTCCT AAGAATGTAC CTCAACAGTC TGAAGGGGCC 
AGCCTCCCAC AAAACCTGGA AACCCCTGCA GTCCCTGAGA AAGGAAAGAG AAGGGGGAGA 
CGGGCGAGCA CAGGTGAGCT GTTTGCAGCA TCCTCCTTGA GCTGGGAAGA AAGAGCCAGG 
GAGTGGCTCA TCAGGGAGGA TGGGAGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006243196.1
CDS	929..2098
Translation	MPEGPELHLASHFVNEICKGLVFGGCVEKSSVSRNPEVPFESSAYHISALARGKELRLTLSPLPGSHPPQKPLSLVFRFGMSGSFQLVPAEALPRHAHLRFYTAPPAPRLALCFVDIRRFGHWDPGGEWQPGRGPCVLLEYERFRENVLRNLSDKAFDRPICEALLDQRFFNGIGNYLRAEILYRLKIPPFEKARTVLEALQQCRLSPELTLSQKVKAKLQNPDLLELCHLVPKEVVQLGGKGYGPERGEEDFAAFRAWLRCYAVPGMSSLRDRHGRTIWFQGDPGPLAPKGGRSRKKKSQETQLEAEDRKEDPPSKSISRTQRARKHCPKNVPQQSEGASLPQNLETPAVPEKGKRRGRRASTGELFAASSLSWEERAREWLIREDGR

Target ORF information:

RefSeq Version	XM_006243134.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nei-like DNA glycosylase 1 (Neil1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006243134.3

ORF Insert Sequence:

ATGCCGGAGG GCCCAGAGCT GCACCTGGCC AGCCACTTTG TGAATGAGAT ATGTAAAGGG 
CTGGTATTCG GTGGGTGTGT GGAGAAGTCC TCTGTCAGCC GAAACCCGGA GGTGCCCTTT 
GAGAGCAGTG CCTACCACAT CTCAGCTTTA GCCCGAGGCA AGGAGCTGCG CTTGACATTG 
AGCCCCCTGC CTGGGTCCCA TCCCCCTCAG AAACCACTGT CCCTTGTCTT CCGCTTTGGT 
ATGTCTGGAT CCTTCCAGCT GGTACCCGCA GAAGCACTGC CGCGCCACGC CCATCTACGT 
TTCTATACGG CCCCACCTGC CCCCCGGCTT GCCCTTTGCT TCGTAGACAT CCGCCGCTTT 
GGCCACTGGG ACCCTGGAGG TGAATGGCAG CCAGGCCGCG GACCCTGTGT CTTGTTGGAG 
TATGAACGGT TCAGAGAGAA CGTGCTTCGG AACCTATCGG ACAAAGCCTT TGACCGGCCC 
ATCTGCGAGG CCTTGTTGGA CCAGAGGTTC TTCAATGGAA TCGGCAACTA TCTGCGGGCA 
GAGATCTTGT ATCGGCTGAA GATCCCCCCT TTTGAGAAGG CCCGTACAGT TCTAGAGGCC 
CTGCAACAGT GCCGGCTGAG CCCAGAGCTG ACCCTGAGCC AGAAGGTCAA GGCCAAACTG 
CAGAACCCAG ACCTGCTGGA ACTGTGTCAC TTGGTGCCCA AGGAAGTGGT TCAGCTGGGG 
GGCAAAGGCT ATGGGCCAGA GCGTGGAGAG GAAGATTTTG CTGCCTTTCG AGCCTGGCTT 
CGGTGCTATG CTGTGCCAGG CATGAGCTCC CTGAGAGACC GGCATGGCCG TACCATTTGG 
TTCCAGGGTG ATCCTGGACC CTTGGCACCC AAAGGGGGCA GATCCCGAAA AAAGAAGTCA 
CAGGAAACAC AGCTGGAGGC TGAGGACAGA AAAGAGGACC CTCCAAGCAA GTCCATTTCC 
AGGACTCAGA GGGCCAGGAA GCACTGTCCT AAGAATGTAC CTCAACAGTC TGAAGGGGCC 
AGCCTCCCAC AAAACCTGGA AACCCCTGCA GTCCCTGAGA AAGGAAAGAG AAGGGGGAGA 
CGGGCGAGCA CAGGTGAGCT GTTTGCAGCA TCCTCCTTGA GCTGGGAAGA AAGAGCCAGG 
GAGTGGCTCA TCAGGGAGGA TGGGAGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Neil1 ( XM_006243136.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006243198.1 Rattus norvegicus nei-like DNA glycosylase 1 (Neil1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa31204
Clone ID Related Accession (Same CDS sequence)	XM_006243135.3 , XM_006243134.3 , XM_006243136.3
Accession Version	XM_006243136.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1170bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	endonuclease 8-like 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006243136.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGGAGG GCCCAGAGCT GCACCTGGCC AGCCACTTTG TGAATGAGAT ATGTAAAGGG 
CTGGTATTCG GTGGGTGTGT GGAGAAGTCC TCTGTCAGCC GAAACCCGGA GGTGCCCTTT 
GAGAGCAGTG CCTACCACAT CTCAGCTTTA GCCCGAGGCA AGGAGCTGCG CTTGACATTG 
AGCCCCCTGC CTGGGTCCCA TCCCCCTCAG AAACCACTGT CCCTTGTCTT CCGCTTTGGT 
ATGTCTGGAT CCTTCCAGCT GGTACCCGCA GAAGCACTGC CGCGCCACGC CCATCTACGT 
TTCTATACGG CCCCACCTGC CCCCCGGCTT GCCCTTTGCT TCGTAGACAT CCGCCGCTTT 
GGCCACTGGG ACCCTGGAGG TGAATGGCAG CCAGGCCGCG GACCCTGTGT CTTGTTGGAG 
TATGAACGGT TCAGAGAGAA CGTGCTTCGG AACCTATCGG ACAAAGCCTT TGACCGGCCC 
ATCTGCGAGG CCTTGTTGGA CCAGAGGTTC TTCAATGGAA TCGGCAACTA TCTGCGGGCA 
GAGATCTTGT ATCGGCTGAA GATCCCCCCT TTTGAGAAGG CCCGTACAGT TCTAGAGGCC 
CTGCAACAGT GCCGGCTGAG CCCAGAGCTG ACCCTGAGCC AGAAGGTCAA GGCCAAACTG 
CAGAACCCAG ACCTGCTGGA ACTGTGTCAC TTGGTGCCCA AGGAAGTGGT TCAGCTGGGG 
GGCAAAGGCT ATGGGCCAGA GCGTGGAGAG GAAGATTTTG CTGCCTTTCG AGCCTGGCTT 
CGGTGCTATG CTGTGCCAGG CATGAGCTCC CTGAGAGACC GGCATGGCCG TACCATTTGG 
TTCCAGGGTG ATCCTGGACC CTTGGCACCC AAAGGGGGCA GATCCCGAAA AAAGAAGTCA 
CAGGAAACAC AGCTGGAGGC TGAGGACAGA AAAGAGGACC CTCCAAGCAA GTCCATTTCC 
AGGACTCAGA GGGCCAGGAA GCACTGTCCT AAGAATGTAC CTCAACAGTC TGAAGGGGCC 
AGCCTCCCAC AAAACCTGGA AACCCCTGCA GTCCCTGAGA AAGGAAAGAG AAGGGGGAGA 
CGGGCGAGCA CAGGTGAGCT GTTTGCAGCA TCCTCCTTGA GCTGGGAAGA AAGAGCCAGG 
GAGTGGCTCA TCAGGGAGGA TGGGAGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006243198.1
CDS	121..1290
Translation	MPEGPELHLASHFVNEICKGLVFGGCVEKSSVSRNPEVPFESSAYHISALARGKELRLTLSPLPGSHPPQKPLSLVFRFGMSGSFQLVPAEALPRHAHLRFYTAPPAPRLALCFVDIRRFGHWDPGGEWQPGRGPCVLLEYERFRENVLRNLSDKAFDRPICEALLDQRFFNGIGNYLRAEILYRLKIPPFEKARTVLEALQQCRLSPELTLSQKVKAKLQNPDLLELCHLVPKEVVQLGGKGYGPERGEEDFAAFRAWLRCYAVPGMSSLRDRHGRTIWFQGDPGPLAPKGGRSRKKKSQETQLEAEDRKEDPPSKSISRTQRARKHCPKNVPQQSEGASLPQNLETPAVPEKGKRRGRRASTGELFAASSLSWEERAREWLIREDGR

Target ORF information:

RefSeq Version	XM_006243136.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nei-like DNA glycosylase 1 (Neil1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006243136.3

ORF Insert Sequence:

ATGCCGGAGG GCCCAGAGCT GCACCTGGCC AGCCACTTTG TGAATGAGAT ATGTAAAGGG 
CTGGTATTCG GTGGGTGTGT GGAGAAGTCC TCTGTCAGCC GAAACCCGGA GGTGCCCTTT 
GAGAGCAGTG CCTACCACAT CTCAGCTTTA GCCCGAGGCA AGGAGCTGCG CTTGACATTG 
AGCCCCCTGC CTGGGTCCCA TCCCCCTCAG AAACCACTGT CCCTTGTCTT CCGCTTTGGT 
ATGTCTGGAT CCTTCCAGCT GGTACCCGCA GAAGCACTGC CGCGCCACGC CCATCTACGT 
TTCTATACGG CCCCACCTGC CCCCCGGCTT GCCCTTTGCT TCGTAGACAT CCGCCGCTTT 
GGCCACTGGG ACCCTGGAGG TGAATGGCAG CCAGGCCGCG GACCCTGTGT CTTGTTGGAG 
TATGAACGGT TCAGAGAGAA CGTGCTTCGG AACCTATCGG ACAAAGCCTT TGACCGGCCC 
ATCTGCGAGG CCTTGTTGGA CCAGAGGTTC TTCAATGGAA TCGGCAACTA TCTGCGGGCA 
GAGATCTTGT ATCGGCTGAA GATCCCCCCT TTTGAGAAGG CCCGTACAGT TCTAGAGGCC 
CTGCAACAGT GCCGGCTGAG CCCAGAGCTG ACCCTGAGCC AGAAGGTCAA GGCCAAACTG 
CAGAACCCAG ACCTGCTGGA ACTGTGTCAC TTGGTGCCCA AGGAAGTGGT TCAGCTGGGG 
GGCAAAGGCT ATGGGCCAGA GCGTGGAGAG GAAGATTTTG CTGCCTTTCG AGCCTGGCTT 
CGGTGCTATG CTGTGCCAGG CATGAGCTCC CTGAGAGACC GGCATGGCCG TACCATTTGG 
TTCCAGGGTG ATCCTGGACC CTTGGCACCC AAAGGGGGCA GATCCCGAAA AAAGAAGTCA 
CAGGAAACAC AGCTGGAGGC TGAGGACAGA AAAGAGGACC CTCCAAGCAA GTCCATTTCC 
AGGACTCAGA GGGCCAGGAA GCACTGTCCT AAGAATGTAC CTCAACAGTC TGAAGGGGCC 
AGCCTCCCAC AAAACCTGGA AACCCCTGCA GTCCCTGAGA AAGGAAAGAG AAGGGGGAGA 
CGGGCGAGCA CAGGTGAGCT GTTTGCAGCA TCCTCCTTGA GCTGGGAAGA AAGAGCCAGG 
GAGTGGCTCA TCAGGGAGGA TGGGAGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Induction of NEIL1 and NEIL2 DNA glycosylases in aniline-induced splenic toxicity.
Toxicology and applied pharmacology251(1)1-7(2011 Feb)
Ma H,Wang J,Abdel-Rahman SZ,Hazra TK,Boor PJ,Khan MF

The human Werner syndrome protein stimulates repair of oxidative DNA base damage by the DNA glycosylase NEIL1.
The Journal of biological chemistry282(36)26591-602(2007 Sep)
Das A,Boldogh I,Lee JW,Harrigan JA,Hegde ML,Piotrowski J,de Souza Pinto N,Ramos W,Greenberg MM,Hazra TK,Mitra S,Bohr VA

A back-up glycosylase in Nth1 knock-out mice is a functional Nei (endonuclease VIII) homologue.
The Journal of biological chemistry277(44)42205-13(2002 Nov)
Takao M,Kanno S,Kobayashi K,Zhang QM,Yonei S,van der Horst GT,Yasui A

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Neil1 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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