Tmem165 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tmem165
Entrez Gene ID	364137
Full Name	transmembrane protein 165
Synonyms	Tparl
General protein information	Preferred Names transmembrane protein 165 Names transmembrane protein 165 TPA regulated locus transmembrane protein TPARL
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 14 Map Location: 14p11

mRNA and Protein(s)

mRNA	Protein	Name
NM_001024802.1	NP_001019973.1	transmembrane protein 165 precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	TMEM165	XP_532375.2
Gallus gallus (chicken)	TMEM165	XP_426336.3
Danio rerio (zebrafish)	tmem165	NP_997848.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011962	XP_320572.4
Magnaporthe oryzae (rice blast fungus)	MGG_12672	XP_003721267.1
Rattus norvegicus (Norway rat)	LOC100911646	XP_003751403.1
Oryza sativa (rice)	Os08g0528500	NP_001062312.1
Oryza sativa (rice)	Os11g0472500	NP_001067880.1
Pan troglodytes (chimpanzee)	TMEM165	XP_001145009.1
Saccharomyces cerevisiae (baker's yeast)	GDT1	NP_009746.1
Xenopus tropicalis (tropical clawed frog)	tmem165	NP_001017260.1
Kluyveromyces lactis	KLLA0E23761g	XP_455024.1
Homo sapiens (human)	TMEM165	NP_060945.2
Caenorhabditis elegans (roundworm)	CELE_Y54F10AL.1	NP_497567.1
Mus musculus (house mouse)	Tmem165	NP_035756.2
Rattus norvegicus (Norway rat)	Tmem165	NP_001019973.1
Drosophila melanogaster (fruit fly)	CG42542	NP_001163615.1
Eremothecium gossypii	AGOS_AEL257W	NP_984604.1
Macaca mulatta (Rhesus monkey)	TMEM165	XP_001088728.1
Bos taurus (cattle)	TMEM165	NP_001192935.1
Arabidopsis thaliana (thale cress)	AT5G36290	NP_851098.1
Neurospora crassa	NCU01990	XP_964855.2

Gene Ontology
Bibliography

Related articles in PubMed

Impact of disease-causing mutations on TMEM165 subcellular localization, a recently identified protein involved in CDG-II.
Rosnoblet C, Legrand D, Demaegd D, Hacine-Gherbi H, de Bettignies G, Bammens R, Borrego C, Duvet S, Morsomme P, Matthijs G, Foulquier F
Human molecular genetics22(14)2914-28(2013 Jul)

Newly characterized Golgi-localized family of proteins is involved in calcium and pH homeostasis in yeast and human cells.
Demaegd D, Foulquier F, Colinet AS, Gremillon L, Legrand D, Mariot P, Peiter E, Van Schaftingen E, Matthijs G, Morsomme P
Proceedings of the National Academy of Sciences of the United States of America110(17)6859-64(2013 Apr)

TMEM165 deficiency causes a congenital disorder of glycosylation.
Foulquier F, Amyere M, Jaeken J, Zeevaert R, Schollen E, Race V, Bammens R, Morelle W, Rosnoblet C, Legrand D, Demaegd D, Buist N, Cheillan D, Guffon N, Morsomme P, Annaert W, Freeze HH, Van Schaftingen E, Vikkula M, Matthijs G
American journal of human genetics91(1)15-26(2012 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Tmem165 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tmem165 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa36034	NM_001024802.1 Latest version!	Rattus norvegicus transmembrane protein 165 (Tmem165), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tmem165 ( NM_001024802.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001019973.1 Rattus norvegicus transmembrane protein 165 (Tmem165), mRNA.

Price & Availability↑

CloneID	ORa36034
Clone ID Related Accession (Same CDS sequence)	NM_001024802.1
Accession Version	NM_001024802.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 972bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1536940800000
Organism	Rattus norvegicus(Norway rat)
Product	transmembrane protein 165 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC097478.1. On Jun 10, 2005 this sequence version replaced XM_344231.2. ##Evidence-Data-START## Transcript exon combination :: BC097478.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906350 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGCCT CGGCCCGGGG GAGCGGCCGG GCGCCGACGC GACGGCTGCT CGTGCTCTTG 
CTGCTTCCGT TGCTCTGGGC CCCGGCTGGG GTCCGCGCTG GCCCCGAGGA AGACCTGAGC 
CACCGGAACC AGGAGCCGCC GGCGCCCGCC CAGCAGCTGC AGCCGCAGCC CGCGGCAGTA 
CAGGGCCTCG AGCCGGCCCG GGCCGAGAAA GGATTTACAC CGGCCGCCCC AGTTCATACC 
AACAGAGAAG ATGCAGCTAC CCAGGCAAAT CTGGGATTTA TCCATGCGTT TGTTGCTGCC 
ATATCAGTCA TCATAGTGTC CGAACTCGGC GACAAGACAT TTTTCATAGC TGCCATCATG 
GCGATGCGCT ATAACCGGCT GACTGTGCTG GCTGGCGCCA TGCTTGCTTT GGCCTTGATG 
ACGTGCTTGT CGGTTTTGTT TGGCTATGCC ACCACAGTCA TCCCCAGGGT GTACACATAC 
TATGTCTCAA CTGCACTCTT TGCCATTTTT GGCATTAGAA TGCTTCGGGA AGGTTTGAAG 
ATGAGCCCAG ACGAGGGTCA GGAGGAGCTC GAAGAAGTGC AAGCAGAGTT GAAGAAGAAA 
GATGAAGAAT TCCAACGAAC CAAACTCTTA AACGGGCCAG ATGTTGAAAC TGGTACAAGC 
ACAGCAATAC CTCAGAAAAA GTGGTTACAC TTTATTTCAC CCATTTTTGT CCAAGCACTC 
ACGTTAACAT TCTTGGCGGA ATGGGGTGAT CGCTCTCAAC TCACTACCAT TGTTCTGGCA 
GCCAGAGAGG ATCCCTATGG TGTGGCAGTG GGTGGCACAG TGGGACACTG CCTGTGCACA 
GGATTGGCAG TAATTGGAGG AAGGATGATA GCACAAAAGA TCTCTGTCAG AACTGTGACG 
ATCATCGGAG GCATCGTGTT TCTGGCATTT GCATTTTCTG CTCTGTTTAT AAGTCCAGAG 
TCTGGTTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001019973.1
CDS	209..1180
Translation	MAASARGSGRAPTRRLLVLLLLPLLWAPAGVRAGPEEDLSHRNQEPPAPAQQLQPQPAAVQGLEPARAEKGFTPAAPVHTNREDAATQANLGFIHAFVAAISVIIVSELGDKTFFIAAIMAMRYNRLTVLAGAMLALALMTCLSVLFGYATTVIPRVYTYYVSTALFAIFGIRMLREGLKMSPDEGQEELEEVQAELKKKDEEFQRTKLLNGPDVETGTSTAIPQKKWLHFISPIFVQALTLTFLAEWGDRSQLTTIVLAAREDPYGVAVGGTVGHCLCTGLAVIGGRMIAQKISVRTVTIIGGIVFLAFAFSALFISPESGF

Target ORF information:

RefSeq Version	NM_001024802.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus transmembrane protein 165 (Tmem165), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001024802.1

ORF Insert Sequence:

ATGGCGGCCT CGGCCCGGGG GAGCGGCCGG GCGCCGACGC GACGGCTGCT CGTGCTCTTG 
CTGCTTCCGT TGCTCTGGGC CCCGGCTGGG GTCCGCGCTG GCCCCGAGGA AGACCTGAGC 
CACCGGAACC AGGAGCCGCC GGCGCCCGCC CAGCAGCTGC AGCCGCAGCC CGCGGCAGTA 
CAGGGCCTCG AGCCGGCCCG GGCCGAGAAA GGATTTACAC CGGCCGCCCC AGTTCATACC 
AACAGAGAAG ATGCAGCTAC CCAGGCAAAT CTGGGATTTA TCCATGCGTT TGTTGCTGCC 
ATATCAGTCA TCATAGTGTC CGAACTCGGC GACAAGACAT TTTTCATAGC TGCCATCATG 
GCGATGCGCT ATAACCGGCT GACTGTGCTG GCTGGCGCCA TGCTTGCTTT GGCCTTGATG 
ACGTGCTTGT CGGTTTTGTT TGGCTATGCC ACCACAGTCA TCCCCAGGGT GTACACATAC 
TATGTCTCAA CTGCACTCTT TGCCATTTTT GGCATTAGAA TGCTTCGGGA AGGTTTGAAG 
ATGAGCCCAG ACGAGGGTCA GGAGGAGCTC GAAGAAGTGC AAGCAGAGTT GAAGAAGAAA 
GATGAAGAAT TCCAACGAAC CAAACTCTTA AACGGGCCAG ATGTTGAAAC TGGTACAAGC 
ACAGCAATAC CTCAGAAAAA GTGGTTACAC TTTATTTCAC CCATTTTTGT CCAAGCACTC 
ACGTTAACAT TCTTGGCGGA ATGGGGTGAT CGCTCTCAAC TCACTACCAT TGTTCTGGCA 
GCCAGAGAGG ATCCCTATGG TGTGGCAGTG GGTGGCACAG TGGGACACTG CCTGTGCACA 
GGATTGGCAG TAATTGGAGG AAGGATGATA GCACAAAAGA TCTCTGTCAG AACTGTGACG 
ATCATCGGAG GCATCGTGTT TCTGGCATTT GCATTTTCTG CTCTGTTTAT AAGTCCAGAG 
TCTGGTTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Impact of disease-causing mutations on TMEM165 subcellular localization, a recently identified protein involved in CDG-II.
Human molecular genetics22(14)2914-28(2013 Jul)
Rosnoblet C,Legrand D,Demaegd D,Hacine-Gherbi H,de Bettignies G,Bammens R,Borrego C,Duvet S,Morsomme P,Matthijs G,Foulquier F

Newly characterized Golgi-localized family of proteins is involved in calcium and pH homeostasis in yeast and human cells.
Proceedings of the National Academy of Sciences of the United States of America110(17)6859-64(2013 Apr)
Demaegd D,Foulquier F,Colinet AS,Gremillon L,Legrand D,Mariot P,Peiter E,Van Schaftingen E,Matthijs G,Morsomme P

TMEM165 deficiency causes a congenital disorder of glycosylation.
American journal of human genetics91(1)15-26(2012 Jul)
Foulquier F,Amyere M,Jaeken J,Zeevaert R,Schollen E,Race V,Bammens R,Morelle W,Rosnoblet C,Legrand D,Demaegd D,Buist N,Cheillan D,Guffon N,Morsomme P,Annaert W,Freeze HH,Van Schaftingen E,Vikkula M,Matthijs G

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Tmem165 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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