Zfp57 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Zfp57
Entrez Gene ID	361783
Full Name	zinc finger protein 57
General protein information	Preferred Names zinc finger protein 57 Names zinc finger protein 57 zfp-57
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 20 Map Location: 20p12
Summary	has transcriptional repressor activity in Schwann cells; may play a role in early stages of Schwann cell development [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008772694.2	XP_008770916.1	zinc finger protein 57 isoform X1
NM_213565.4	NP_998730.2	zinc finger protein 57

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Zfp57	NP_998730.2
Homo sapiens (human)	ZFP57	NP_001103279.2
Pan troglodytes (chimpanzee)	ZFP57	XP_518319.3
Bos taurus (cattle)	ZFP57	XP_005223766.1
Mus musculus (house mouse)	Zfp57	NP_001013767.1
Macaca mulatta (Rhesus monkey)	LOC711428	XP_002808422.1

Gene Ontology
Bibliography

Related articles in PubMed

On how mammalian transcription factors recognize methylated DNA.
Buck-Koehntop BA, Defossez PA
Epigenetics8(2)131-7(2013 Feb)

Hsp72 preserves muscle function and slows progression of severe muscular dystrophy.
Gehrig SM, van der Poel C, Sayer TA, Schertzer JD, Henstridge DC, Church JE, Lamon S, Russell AP, Davies KE, Febbraio MA, Lynch GS
Nature484(7394)394-8(2012 Apr)

A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints.
Li X, Ito M, Zhou F, Youngson N, Zuo X, Leder P, Ferguson-Smith AC
Developmental cell15(4)547-57(2008 Oct)

Hypomethylation of multiple imprinted loci in individuals with transient neonatal diabetes is associated with mutations in ZFP57.
Mackay DJ, Callaway JL, Marks SM, White HE, Acerini CL, Boonen SE, Dayanikli P, Firth HV, Goodship JA, Haemers AP, Hahnemann JM, Kordonouri O, Masoud AF, Oestergaard E, Storr J, Ellard S, Hattersley AT, Robinson DO, Temple IK
Nature genetics40(8)949-51(2008 Aug)

Identification and characterization of ZFP-57, a novel zinc finger transcription factor in the mammalian peripheral nervous system.
Alonso MB, Zoidl G, Taveggia C, Bosse F, Zoidl C, Rahman M, Parmantier E, Dean CH, Harris BS, Wrabetz L, Müller HW, Jessen KR, Mirsky R
The Journal of biological chemistry279(24)25653-64(2004 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Zfp57 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Zfp57 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05691	NM_213565.4 Latest version!	Rattus norvegicus zinc finger protein 57 (Zfp57), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa05691	XM_008772694.2 Latest version!	Rattus norvegicus zinc finger protein 57 (Zfp57), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Zfp57 ( NM_213565.4 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_998730.2 Rattus norvegicus zinc finger protein 57 (Zfp57), mRNA.

Price & Availability↑

CloneID	ORa05691
Clone ID Related Accession (Same CDS sequence)	XM_008772694.2 , NM_213565.4
Accession Version	NM_213565.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1221bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1537459200000
Organism	Rattus norvegicus(Norway rat)
Product	zinc finger protein 57
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CA511208.1 and BC127468.1. On Oct 17, 2009 this sequence version replaced NM_213565.3. ##Evidence-Data-START## Transcript exon combination :: CA511208.1, DY312591.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGCTA AGAAACAGTC TAAGTCTGCC AAGGCGTTAA GGACAACAGT CAGATATGAG 
GACGTGGCAG TGTCTTTCAC CCAGGAAGAA TGGGAATATC TGACTTCTAC ACAGAAGACC 
CTTTACCAAA AAGTGATGTC AGAAACCTTC AAGAACCTGA CATTTGTGGA AAGCAAGAAG 
AAACCTCAAG AACCTAACCC AAATCTGAAA GATAAGGATG ATGATAAGTC CTCCACTTGC 
ACAGGGGTAT TCAAAGGTGG ACCATTCTTT TTCTGTCTCA CCTGTGGCAA ATGTTTCAAA 
AAGAACACCT TCCTCTTTAA TCACCAGTTT CCTGTGAGGT CCCGGAGGCT GGCGGTCACA 
AAGCCGCAAA GCCGCAAAGC CCTCGGTCAT AAGCCCCAGC ATCGCGGAGA CAGGCCTTTC 
TTTTGCAATC TCTGTGGCAA GACTTATCGT GATGCTTCTG GACTGAGCCG TCACCGACGT 
GCTCACGTAG GTTATAGGCC CCGTTCCTGC CCTGAGTGTG GAAAGTGCTT CCGGGATCAG 
TCTGAGGTCA ACCGCCACCT GAAGGTACAC CAAAACAAGA AACCAGTGGC TGGCAGCCAC 
GTGAAAGTAC ACCAAAACAA GCCAGTGGCT AGCAACCAGA AGCAGAAGGG TAGGGTTCCA 
CCTACAACAC GTGAATCCCC AGCGCCAGCC CTCAGGCATC TGAAAGTGAT CCAGGGACCA 
GTGGCCAGGG CTAAGGCACG GAGCAGCAGA GCTTCATCCC TGGAGGTCAG ATCCACCTCA 
GTTACAGTGG CCCGCCCAAG AGAAAAGGTC TATTGTCCCT ATTGCCGGAT CACTTTTACC 
ATGAGAACCT GTCTCTTGAA CCACCTCAAG ATCCACTTCC GGCGTCAACC CAACCAGCAC 
TTCTGTTGCA AAGAGTCCCA CTCGTCCAAC ACACTCAGGA TGCAAAAGAT CTACAATTGC 
CCCGTCTGCG ACAGCTCCTT TAGGGGGAAG GAGAGCCTGC TGAATCACTT GTGCTCCCGA 
AGACCAATCA GGCTCAGTAA ATGCTGGGAA ATCCTGGGTC ATCTGCTTGG CTATCTTCGT 
GAACCCTTGG GAAATATTTT TAAAGTAAGG GAATCCAGGA AGAGAAGACG GAAACGCATA 
AGCAGTGATA GTTCTGAAAC AGAAGGCCCG TCTGGGAGTG ATGAGGTGAT GGAGGTTGAC 
ACCGACTCTG ACCTCTCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_998730.2
CDS	265..1485
Translation	MAAKKQSKSAKALRTTVRYEDVAVSFTQEEWEYLTSTQKTLYQKVMSETFKNLTFVESKKKPQEPNPNLKDKDDDKSSTCTGVFKGGPFFFCLTCGKCFKKNTFLFNHQFPVRSRRLAVTKPQSRKALGHKPQHRGDRPFFCNLCGKTYRDASGLSRHRRAHVGYRPRSCPECGKCFRDQSEVNRHLKVHQNKKPVAGSHVKVHQNKPVASNQKQKGRVPPTTRESPAPALRHLKVIQGPVARAKARSSRASSLEVRSTSVTVARPREKVYCPYCRITFTMRTCLLNHLKIHFRRQPNQHFCCKESHSSNTLRMQKIYNCPVCDSSFRGKESLLNHLCSRRPIRLSKCWEILGHLLGYLREPLGNIFKVRESRKRRRKRISSDSSETEGPSGSDEVMEVDTDSDLS

Target ORF information:

RefSeq Version	NM_213565.4
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus zinc finger protein 57 (Zfp57), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_213565.4

ORF Insert Sequence:

ATGGCAGCTA AGAAACAGTC TAAGTCTGCC AAGGCGTTAA GGACAACAGT CAGATATGAG 
GACGTGGCAG TGTCTTTCAC CCAGGAAGAA TGGGAATATC TGACTTCTAC ACAGAAGACC 
CTTTACCAAA AAGTGATGTC AGAAACCTTC AAGAACCTGA CATTTGTGGA AAGCAAGAAG 
AAACCTCAAG AACCTAACCC AAATCTGAAA GATAAGGATG ATGATAAGTC CTCCACTTGC 
ACAGGGGTAT TCAAAGGTGG ACCATTCTTT TTCTGTCTCA CCTGTGGCAA ATGTTTCAAA 
AAGAACACCT TCCTCTTTAA TCACCAGTTT CCTGTGAGGT CCCGGAGGCT GGCGGTCACA 
AAGCCGCAAA GCCGCAAAGC CCTCGGTCAT AAGCCCCAGC ATCGCGGAGA CAGGCCTTTC 
TTTTGCAATC TCTGTGGCAA GACTTATCGT GATGCTTCTG GACTGAGCCG TCACCGACGT 
GCTCACGTAG GTTATAGGCC CCGTTCCTGC CCTGAGTGTG GAAAGTGCTT CCGGGATCAG 
TCTGAGGTCA ACCGCCACCT GAAGGTACAC CAAAACAAGA AACCAGTGGC TGGCAGCCAC 
GTGAAAGTAC ACCAAAACAA GCCAGTGGCT AGCAACCAGA AGCAGAAGGG TAGGGTTCCA 
CCTACAACAC GTGAATCCCC AGCGCCAGCC CTCAGGCATC TGAAAGTGAT CCAGGGACCA 
GTGGCCAGGG CTAAGGCACG GAGCAGCAGA GCTTCATCCC TGGAGGTCAG ATCCACCTCA 
GTTACAGTGG CCCGCCCAAG AGAAAAGGTC TATTGTCCCT ATTGCCGGAT CACTTTTACC 
ATGAGAACCT GTCTCTTGAA CCACCTCAAG ATCCACTTCC GGCGTCAACC CAACCAGCAC 
TTCTGTTGCA AAGAGTCCCA CTCGTCCAAC ACACTCAGGA TGCAAAAGAT CTACAATTGC 
CCCGTCTGCG ACAGCTCCTT TAGGGGGAAG GAGAGCCTGC TGAATCACTT GTGCTCCCGA 
AGACCAATCA GGCTCAGTAA ATGCTGGGAA ATCCTGGGTC ATCTGCTTGG CTATCTTCGT 
GAACCCTTGG GAAATATTTT TAAAGTAAGG GAATCCAGGA AGAGAAGACG GAAACGCATA 
AGCAGTGATA GTTCTGAAAC AGAAGGCCCG TCTGGGAGTG ATGAGGTGAT GGAGGTTGAC 
ACCGACTCTG ACCTCTCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Zfp57 ( XM_008772694.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008770916.1 Rattus norvegicus zinc finger protein 57 (Zfp57), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa05691
Clone ID Related Accession (Same CDS sequence)	XM_008772694.2 , NM_213565.4
Accession Version	XM_008772694.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1221bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	zinc finger protein 57 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005119.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008772694.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGCTA AGAAACAGTC TAAGTCTGCC AAGGCGTTAA GGACAACAGT CAGATATGAG 
GACGTGGCAG TGTCTTTCAC CCAGGAAGAA TGGGAATATC TGACTTCTAC ACAGAAGACC 
CTTTACCAAA AAGTGATGTC AGAAACCTTC AAGAACCTGA CATTTGTGGA AAGCAAGAAG 
AAACCTCAAG AACCTAACCC AAATCTGAAA GATAAGGATG ATGATAAGTC CTCCACTTGC 
ACAGGGGTAT TCAAAGGTGG ACCATTCTTT TTCTGTCTCA CCTGTGGCAA ATGTTTCAAA 
AAGAACACCT TCCTCTTTAA TCACCAGTTT CCTGTGAGGT CCCGGAGGCT GGCGGTCACA 
AAGCCGCAAA GCCGCAAAGC CCTCGGTCAT AAGCCCCAGC ATCGCGGAGA CAGGCCTTTC 
TTTTGCAATC TCTGTGGCAA GACTTATCGT GATGCTTCTG GACTGAGCCG TCACCGACGT 
GCTCACGTAG GTTATAGGCC CCGTTCCTGC CCTGAGTGTG GAAAGTGCTT CCGGGATCAG 
TCTGAGGTCA ACCGCCACCT GAAGGTACAC CAAAACAAGA AACCAGTGGC TGGCAGCCAC 
GTGAAAGTAC ACCAAAACAA GCCAGTGGCT AGCAACCAGA AGCAGAAGGG TAGGGTTCCA 
CCTACAACAC GTGAATCCCC AGCGCCAGCC CTCAGGCATC TGAAAGTGAT CCAGGGACCA 
GTGGCCAGGG CTAAGGCACG GAGCAGCAGA GCTTCATCCC TGGAGGTCAG ATCCACCTCA 
GTTACAGTGG CCCGCCCAAG AGAAAAGGTC TATTGTCCCT ATTGCCGGAT CACTTTTACC 
ATGAGAACCT GTCTCTTGAA CCACCTCAAG ATCCACTTCC GGCGTCAACC CAACCAGCAC 
TTCTGTTGCA AAGAGTCCCA CTCGTCCAAC ACACTCAGGA TGCAAAAGAT CTACAATTGC 
CCCGTCTGCG ACAGCTCCTT TAGGGGGAAG GAGAGCCTGC TGAATCACTT GTGCTCCCGA 
AGACCAATCA GGCTCAGTAA ATGCTGGGAA ATCCTGGGTC ATCTGCTTGG CTATCTTCGT 
GAACCCTTGG GAAATATTTT TAAAGTAAGG GAATCCAGGA AGAGAAGACG GAAACGCATA 
AGCAGTGATA GTTCTGAAAC AGAAGGCCCG TCTGGGAGTG ATGAGGTGAT GGAGGTTGAC 
ACCGACTCTG ACCTCTCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008770916.1
CDS	438..1658
Translation	MAAKKQSKSAKALRTTVRYEDVAVSFTQEEWEYLTSTQKTLYQKVMSETFKNLTFVESKKKPQEPNPNLKDKDDDKSSTCTGVFKGGPFFFCLTCGKCFKKNTFLFNHQFPVRSRRLAVTKPQSRKALGHKPQHRGDRPFFCNLCGKTYRDASGLSRHRRAHVGYRPRSCPECGKCFRDQSEVNRHLKVHQNKKPVAGSHVKVHQNKPVASNQKQKGRVPPTTRESPAPALRHLKVIQGPVARAKARSSRASSLEVRSTSVTVARPREKVYCPYCRITFTMRTCLLNHLKIHFRRQPNQHFCCKESHSSNTLRMQKIYNCPVCDSSFRGKESLLNHLCSRRPIRLSKCWEILGHLLGYLREPLGNIFKVRESRKRRRKRISSDSSETEGPSGSDEVMEVDTDSDLS

Target ORF information:

RefSeq Version	XM_008772694.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus zinc finger protein 57 (Zfp57), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008772694.2

ORF Insert Sequence:

ATGGCAGCTA AGAAACAGTC TAAGTCTGCC AAGGCGTTAA GGACAACAGT CAGATATGAG 
GACGTGGCAG TGTCTTTCAC CCAGGAAGAA TGGGAATATC TGACTTCTAC ACAGAAGACC 
CTTTACCAAA AAGTGATGTC AGAAACCTTC AAGAACCTGA CATTTGTGGA AAGCAAGAAG 
AAACCTCAAG AACCTAACCC AAATCTGAAA GATAAGGATG ATGATAAGTC CTCCACTTGC 
ACAGGGGTAT TCAAAGGTGG ACCATTCTTT TTCTGTCTCA CCTGTGGCAA ATGTTTCAAA 
AAGAACACCT TCCTCTTTAA TCACCAGTTT CCTGTGAGGT CCCGGAGGCT GGCGGTCACA 
AAGCCGCAAA GCCGCAAAGC CCTCGGTCAT AAGCCCCAGC ATCGCGGAGA CAGGCCTTTC 
TTTTGCAATC TCTGTGGCAA GACTTATCGT GATGCTTCTG GACTGAGCCG TCACCGACGT 
GCTCACGTAG GTTATAGGCC CCGTTCCTGC CCTGAGTGTG GAAAGTGCTT CCGGGATCAG 
TCTGAGGTCA ACCGCCACCT GAAGGTACAC CAAAACAAGA AACCAGTGGC TGGCAGCCAC 
GTGAAAGTAC ACCAAAACAA GCCAGTGGCT AGCAACCAGA AGCAGAAGGG TAGGGTTCCA 
CCTACAACAC GTGAATCCCC AGCGCCAGCC CTCAGGCATC TGAAAGTGAT CCAGGGACCA 
GTGGCCAGGG CTAAGGCACG GAGCAGCAGA GCTTCATCCC TGGAGGTCAG ATCCACCTCA 
GTTACAGTGG CCCGCCCAAG AGAAAAGGTC TATTGTCCCT ATTGCCGGAT CACTTTTACC 
ATGAGAACCT GTCTCTTGAA CCACCTCAAG ATCCACTTCC GGCGTCAACC CAACCAGCAC 
TTCTGTTGCA AAGAGTCCCA CTCGTCCAAC ACACTCAGGA TGCAAAAGAT CTACAATTGC 
CCCGTCTGCG ACAGCTCCTT TAGGGGGAAG GAGAGCCTGC TGAATCACTT GTGCTCCCGA 
AGACCAATCA GGCTCAGTAA ATGCTGGGAA ATCCTGGGTC ATCTGCTTGG CTATCTTCGT 
GAACCCTTGG GAAATATTTT TAAAGTAAGG GAATCCAGGA AGAGAAGACG GAAACGCATA 
AGCAGTGATA GTTCTGAAAC AGAAGGCCCG TCTGGGAGTG ATGAGGTGAT GGAGGTTGAC 
ACCGACTCTG ACCTCTCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

On how mammalian transcription factors recognize methylated DNA.
Epigenetics8(2)131-7(2013 Feb)
Buck-Koehntop BA,Defossez PA

Hsp72 preserves muscle function and slows progression of severe muscular dystrophy.
Nature484(7394)394-8(2012 Apr)
Gehrig SM,van der Poel C,Sayer TA,Schertzer JD,Henstridge DC,Church JE,Lamon S,Russell AP,Davies KE,Febbraio MA,Lynch GS

A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints.
Developmental cell15(4)547-57(2008 Oct)
Li X,Ito M,Zhou F,Youngson N,Zuo X,Leder P,Ferguson-Smith AC

Hypomethylation of multiple imprinted loci in individuals with transient neonatal diabetes is associated with mutations in ZFP57.
Nature genetics40(8)949-51(2008 Aug)
Mackay DJ,Callaway JL,Marks SM,White HE,Acerini CL,Boonen SE,Dayanikli P,Firth HV,Goodship JA,Haemers AP,Hahnemann JM,Kordonouri O,Masoud AF,Oestergaard E,Storr J,Ellard S,Hattersley AT,Robinson DO,Temple IK

Identification and characterization of ZFP-57, a novel zinc finger transcription factor in the mammalian peripheral nervous system.
The Journal of biological chemistry279(24)25653-64(2004 Jun)
Alonso MB,Zoidl G,Taveggia C,Bosse F,Zoidl C,Rahman M,Parmantier E,Dean CH,Harris BS,Wrabetz L,Müller HW,Jessen KR,Mirsky R

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Zfp57 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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