Dusp22 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dusp22
Entrez Gene ID	361242
Full Name	dual specificity phosphatase 22
General protein information	Preferred Names dual specificity phosphatase 22 Names dual specificity protein phosphatase 22
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 17 Map Location: 17p12

mRNA and Protein(s)

mRNA	Protein	Name
XM_017600602.1	XP_017456091.1	dual specificity protein phosphatase 22 isoform X1
XM_006253888.2	XP_006253950.1	dual specificity protein phosphatase 22 isoform X3
NM_001108412.1	NP_001101882.1	dual specificity protein phosphatase 22
XM_006253889.2	XP_006253951.1	dual specificity protein phosphatase 22 isoform X4
XM_017600603.1	XP_017456092.1	dual specificity protein phosphatase 22 isoform X2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	DUSP22	XP_005640025.1
Gallus gallus (chicken)	DUSP22	XP_418974.2
Xenopus tropicalis (tropical clawed frog)	dusp22	NP_001011043.1
Danio rerio (zebrafish)	dusp22b	NP_001017742.2
Pan troglodytes (chimpanzee)	DUSP22	NP_001153523.1
Mus musculus (house mouse)	Dusp22	NP_001033044.1
Homo sapiens (human)	DUSP22	NP_001273484.1
Rattus norvegicus (Norway rat)	Dusp22	NP_001101882.1
Bos taurus (cattle)	DUSP22	XP_002697658.2
Drosophila melanogaster (fruit fly)	CG10089	NP_648654.1
Macaca mulatta (Rhesus monkey)	DUSP22	XP_002803616.1

Gene Ontology
Bibliography

Related articles in PubMed

The phosphatase JKAP/DUSP22 inhibits T-cell receptor signalling and autoimmunity by inactivating Lck.
Li JP, Yang CY, Chuang HC, Lan JL, Chen DY, Chen YM, Wang X, Chen AJ, Belmont JW, Tan TH
Nature communications53618(2014 Apr)

JNK pathway-associated phosphatase dephosphorylates focal adhesion kinase and suppresses cell migration.
Li JP, Fu YN, Chen YR, Tan TH
The Journal of biological chemistry285(8)5472-8(2010 Feb)

Regulation of STAT3-mediated signaling by LMW-DSP2.
Sekine Y, Tsuji S, Ikeda O, Sato N, Aoki N, Aoyama K, Sugiyama K, Matsuda T
Oncogene25(42)5801-6(2006 Sep)

The dual specificity JKAP specifically activates the c-Jun N-terminal kinase pathway.
Chen AJ, Zhou G, Juan T, Colicos SM, Cannon JP, Cabriera-Hansen M, Meyer CF, Jurecic R, Copeland NG, Gilbert DJ, Jenkins NA, Fletcher F, Tan TH, Belmont JW
The Journal of biological chemistry277(39)36592-601(2002 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Dusp22 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dusp22 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa07290	NM_001108412.1 Latest version!	Rattus norvegicus dual specificity phosphatase 22 (Dusp22), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
ORa37851	XM_006253888.2 Latest version!	Rattus norvegicus dual specificity phosphatase 22 (Dusp22), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
ORa37852	XM_006253889.2 Latest version!	Rattus norvegicus dual specificity phosphatase 22 (Dusp22), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
ORa59091	XM_017600602.1 Latest version!	Rattus norvegicus dual specificity phosphatase 22 (Dusp22), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
ORa59092	XM_017600603.1 Latest version!	Rattus norvegicus dual specificity phosphatase 22 (Dusp22), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dusp22 ( NM_001108412.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101882.1 Rattus norvegicus dual specificity phosphatase 22 (Dusp22), mRNA.

Price & Availability↑

CloneID	ORa07290
Clone ID Related Accession (Same CDS sequence)	NM_001108412.1
Accession Version	NM_001108412.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 555bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1555516800000
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity protein phosphatase 22
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473977.1. On or before Oct 4, 2007 this sequence version replaced XM_341523.3, XM_001061713.1. ##Evidence-Data-START## Transcript exon combination :: FN802846.1, FM132124.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGGGAGTG GGATGAGCCA GATCCTGCCG GGCCTGTACA TTGGCAACTT CAAAGATGCA 
AGAGATGCAG AACAATTGAG CAGGAACAAG GTGACACACA TTCTTTCTGT GCACGACACT 
GCCAGGCCCA TGCTGGAGGG AGTTAAATAC CTGTGTATTC CAGCAGCAGA CTCACCGTCT 
CAAAACCTGA CAAGACATTT CAAAGAAAGT ATTAAATTCA TTCATGAGTG CCGACTCCAG 
GGTGAGGGCT GTCTTGTACA TTGCCTGGCT GGGGTCTCCA GGAGTGTGAC ACTGGTGATC 
GCATACATCA TGACTGTCAC CGACTTTGGC TGGGAAGAGG CCTTACACAC CGTTCGTGCA 
GGGAGGTCCT GTGCCAACCC CAACCTGGGC TTCCAAAGGC AGCTGCAGGA GTTTGAGAAA 
CACGAAGTGC GGCAGTATCG GCAATGGCTG AGAGAAGAAT ATGGAGAGAA CCCCTTGCGG 
GATGCAGAAG AAGCCAAAAG CATTCTGGCT GCCCCGGGAA TTCTGAAGTA CTGGGCCTTT 
CTCAGAAGAC TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101882.1
CDS	122..676
Translation	MGSGMSQILPGLYIGNFKDARDAEQLSRNKVTHILSVHDTARPMLEGVKYLCIPAADSPSQNLTRHFKESIKFIHECRLQGEGCLVHCLAGVSRSVTLVIAYIMTVTDFGWEEALHTVRAGRSCANPNLGFQRQLQEFEKHEVRQYRQWLREEYGENPLRDAEEAKSILAAPGILKYWAFLRRL

Target ORF information:

RefSeq Version	NM_001108412.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual specificity phosphatase 22 (Dusp22), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108412.1

ORF Insert Sequence:

ATGGGGAGTG GGATGAGCCA GATCCTGCCG GGCCTGTACA TTGGCAACTT CAAAGATGCA 
AGAGATGCAG AACAATTGAG CAGGAACAAG GTGACACACA TTCTTTCTGT GCACGACACT 
GCCAGGCCCA TGCTGGAGGG AGTTAAATAC CTGTGTATTC CAGCAGCAGA CTCACCGTCT 
CAAAACCTGA CAAGACATTT CAAAGAAAGT ATTAAATTCA TTCATGAGTG CCGACTCCAG 
GGTGAGGGCT GTCTTGTACA TTGCCTGGCT GGGGTCTCCA GGAGTGTGAC ACTGGTGATC 
GCATACATCA TGACTGTCAC CGACTTTGGC TGGGAAGAGG CCTTACACAC CGTTCGTGCA 
GGGAGGTCCT GTGCCAACCC CAACCTGGGC TTCCAAAGGC AGCTGCAGGA GTTTGAGAAA 
CACGAAGTGC GGCAGTATCG GCAATGGCTG AGAGAAGAAT ATGGAGAGAA CCCCTTGCGG 
GATGCAGAAG AAGCCAAAAG CATTCTGGCT GCCCCGGGAA TTCTGAAGTA CTGGGCCTTT 
CTCAGAAGAC TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dusp22 ( XM_006253888.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006253950.1 Rattus norvegicus dual specificity phosphatase 22 (Dusp22), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa37851
Clone ID Related Accession (Same CDS sequence)	XM_006253888.2
Accession Version	XM_006253888.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 609bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity protein phosphatase 22 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005116.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006253888.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGGATA TGATCCTGCC GGGCCTGTAC ATTGGCAACT TCAAAGATGC AAGAGATGCA 
GAACAATTGA GCAGGAACAA GGTGACACAC ATTCTTTCTG TGCACGACAC TGCCAGGCCC 
ATGCTGGAGG GAGTTAAATA CCTGTGTATT CCAGCAGCAG ACTCACCGTC TCAAAACCTG 
ACAAGACATT TCAAAGAAAG TATTAAATTC ATTCATGAGT GCCGACTCCA GGGTGAGGGC 
TGTCTTGTAC ATTGCCTGGC TGGGGTCTCC AGGAGTGTGA CACTGGTGAT CGCATACATC 
ATGACTGTCA CCGACTTTGG CTGGGAAGAG GCCTTACACA CCGTTCGTGC AGGGAGGTCC 
TGTGCCAACC CCAACCTGGG CTTCCAAAGG CAGCTGCAGG AGTTTGAGAA ACACGAAGTG 
CGGCAGTATC GGCAATGGCT GAGAGAAGAA TATGGAGAGA ACCCCTTGCG GGATGCAGAA 
GAAGCCAAAA GCATTCTGGG TAAATATAAA GAGCAAGGGC GCATGGAGCC CCGGCCTAGC 
AGCAGGCGGT GGAGCAGCCT TTCAGCCCTG CCTGCTCTCA CCTACAATAA CTACACAACA 
GAGACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006253950.1
CDS	79..687
Translation	MLDMILPGLYIGNFKDARDAEQLSRNKVTHILSVHDTARPMLEGVKYLCIPAADSPSQNLTRHFKESIKFIHECRLQGEGCLVHCLAGVSRSVTLVIAYIMTVTDFGWEEALHTVRAGRSCANPNLGFQRQLQEFEKHEVRQYRQWLREEYGENPLRDAEEAKSILGKYKEQGRMEPRPSSRRWSSLSALPALTYNNYTTET

Target ORF information:

RefSeq Version	XM_006253888.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual specificity phosphatase 22 (Dusp22), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006253888.2

ORF Insert Sequence:

ATGCTGGATA TGATCCTGCC GGGCCTGTAC ATTGGCAACT TCAAAGATGC AAGAGATGCA 
GAACAATTGA GCAGGAACAA GGTGACACAC ATTCTTTCTG TGCACGACAC TGCCAGGCCC 
ATGCTGGAGG GAGTTAAATA CCTGTGTATT CCAGCAGCAG ACTCACCGTC TCAAAACCTG 
ACAAGACATT TCAAAGAAAG TATTAAATTC ATTCATGAGT GCCGACTCCA GGGTGAGGGC 
TGTCTTGTAC ATTGCCTGGC TGGGGTCTCC AGGAGTGTGA CACTGGTGAT CGCATACATC 
ATGACTGTCA CCGACTTTGG CTGGGAAGAG GCCTTACACA CCGTTCGTGC AGGGAGGTCC 
TGTGCCAACC CCAACCTGGG CTTCCAAAGG CAGCTGCAGG AGTTTGAGAA ACACGAAGTG 
CGGCAGTATC GGCAATGGCT GAGAGAAGAA TATGGAGAGA ACCCCTTGCG GGATGCAGAA 
GAAGCCAAAA GCATTCTGGG TAAATATAAA GAGCAAGGGC GCATGGAGCC CCGGCCTAGC 
AGCAGGCGGT GGAGCAGCCT TTCAGCCCTG CCTGCTCTCA CCTACAATAA CTACACAACA 
GAGACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dusp22 ( XM_006253889.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006253951.1 Rattus norvegicus dual specificity phosphatase 22 (Dusp22), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa37852
Clone ID Related Accession (Same CDS sequence)	XM_006253889.2
Accession Version	XM_006253889.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 618bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity protein phosphatase 22 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005116.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006253889.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAGTG GGATGAGCCA GATCCTGCCG GGCCTGTACA TTGGCAACTT CAAAGATGCA 
AGAGATGCAG AACAATTGAG CAGGAACAAG GTGACACACA TTCTTTCTGT GCACGACACT 
GCCAGGCCCA TGCTGGAGGG AGTTAAATAC CTGTGTATTC CAGCAGCAGA CTCACCGTCT 
CAAAACCTGA CAAGACATTT CAAAGAAAGT ATTAAATTCA TTCATGAGTG CCGACTCCAG 
GGTGAGGGCT GTCTTGTACA TTGCCTGGCT GGGGTCTCCA GGAGTGTGAC ACTGGTGATC 
GCATACATCA TGACTGTCAC CGACTTTGGC TGGGAAGAGG CCTTACACAC CGTTCGTGCA 
GGGAGGTCCT GTGCCAACCC CAACCTGGGC TTCCAAAGGC AGCTGCAGGA GTTTGAGAAA 
CACGAAGTGC GGCAGTATCG GCAATGGCTG AGAGAAGAAT ATGGAGAGAA CCCCTTGCGG 
GATGCAGAAG AAGCCAAAAG CATTCTGGGT AAATATAAAG AGCAAGGGCG CATGGAGCCC 
CGGCCTAGCA GCAGGCGGTG GAGCAGCCTT TCAGCCCTGC CTGCTCTCAC CTACAATAAC 
TACACAACAG AGACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006253951.1
CDS	343..960
Translation	MGSGMSQILPGLYIGNFKDARDAEQLSRNKVTHILSVHDTARPMLEGVKYLCIPAADSPSQNLTRHFKESIKFIHECRLQGEGCLVHCLAGVSRSVTLVIAYIMTVTDFGWEEALHTVRAGRSCANPNLGFQRQLQEFEKHEVRQYRQWLREEYGENPLRDAEEAKSILGKYKEQGRMEPRPSSRRWSSLSALPALTYNNYTTET

Target ORF information:

RefSeq Version	XM_006253889.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual specificity phosphatase 22 (Dusp22), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006253889.2

ORF Insert Sequence:

ATGGGGAGTG GGATGAGCCA GATCCTGCCG GGCCTGTACA TTGGCAACTT CAAAGATGCA 
AGAGATGCAG AACAATTGAG CAGGAACAAG GTGACACACA TTCTTTCTGT GCACGACACT 
GCCAGGCCCA TGCTGGAGGG AGTTAAATAC CTGTGTATTC CAGCAGCAGA CTCACCGTCT 
CAAAACCTGA CAAGACATTT CAAAGAAAGT ATTAAATTCA TTCATGAGTG CCGACTCCAG 
GGTGAGGGCT GTCTTGTACA TTGCCTGGCT GGGGTCTCCA GGAGTGTGAC ACTGGTGATC 
GCATACATCA TGACTGTCAC CGACTTTGGC TGGGAAGAGG CCTTACACAC CGTTCGTGCA 
GGGAGGTCCT GTGCCAACCC CAACCTGGGC TTCCAAAGGC AGCTGCAGGA GTTTGAGAAA 
CACGAAGTGC GGCAGTATCG GCAATGGCTG AGAGAAGAAT ATGGAGAGAA CCCCTTGCGG 
GATGCAGAAG AAGCCAAAAG CATTCTGGGT AAATATAAAG AGCAAGGGCG CATGGAGCCC 
CGGCCTAGCA GCAGGCGGTG GAGCAGCCTT TCAGCCCTGC CTGCTCTCAC CTACAATAAC 
TACACAACAG AGACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dusp22 ( XM_017600602.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017456091.1 Rattus norvegicus dual specificity phosphatase 22 (Dusp22), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa59091
Clone ID Related Accession (Same CDS sequence)	XM_017600602.1
Accession Version	XM_017600602.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 711bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity protein phosphatase 22 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005116.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGAGAT CACATGCTCA TACTAGAGCT GTAAAGTCCC ATGGGAGCTG GTATCTGGCC 
CCTTGCGGCC TATGCAGGAA NGNAGAGTCG AGCTCTTTAG AACTCCAGAG GAAGATCCTG 
CCGGGCCTGT ACATTGGCAA CTTCAAAGAT GCAAGAGATG CAGAACAATT GAGCAGGAAC 
AAGGTGACAC ACATTCTTTC TGTGCACGAC ACTGCCAGGC CCATGCTGGA GGGAGTTAAA 
TACCTGTGTA TTCCAGCAGC AGACTCACCG TCTCAAAACC TGACAAGACA TTTCAAAGAA 
AGTATTAAAT TCATTCATGA GTGCCGACTC CAGGGTGAGG GCTGTCTTGT ACATTGCCTG 
GCTGGGGTCT CCAGGAGTGT GACACTGGTG ATCGCATACA TCATGACTGT CACCGACTTT 
GGCTGGGAAG AGGCCTTACA CACCGTTCGT GCAGGGAGGT CCTGTGCCAA CCCCAACCTG 
GGCTTCCAAA GGCAGCTGCA GGAGTTTGAG AAACACGAAG TGCGGCAGTA TCGGCAATGG 
CTGAGAGAAG AATATGGAGA GAACCCCTTG CGGGATGCAG AAGAAGCCAA AAGCATTCTG 
GGTAAATATA AAGAGCAAGG GCGCATGGAG CCCCGGCCTA GCAGCAGGCG GTGGAGCAGC 
CTTTCAGCCC TGCCTGCTCT CACCTACAAT AACTACACAA CAGAGACCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017456091.1
CDS	5960..6670
Translation	MLRSHAHTRAVKSHGSWYLAPCGLCRnullnullESSSLELQRKILPGLYIGNFKDARDAEQLSRNKVTHILSVHDTARPMLEGVKYLCIPAADSPSQNLTRHFKESIKFIHECRLQGEGCLVHCLAGVSRSVTLVIAYIMTVTDFGWEEALHTVRAGRSCANPNLGFQRQLQEFEKHEVRQYRQWLREEYGENPLRDAEEAKSILGKYKEQGRMEPRPSSRRWSSLSALPALTYNNYTTET

Target ORF information:

RefSeq Version	XM_017600602.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual specificity phosphatase 22 (Dusp22), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017600602.1

ORF Insert Sequence:

ATGCTGAGAT CACATGCTCA TACTAGAGCT GTAAAGTCCC ATGGGAGCTG GTATCTGGCC 
CCTTGCGGCC TATGCAGGAA NGNAGAGTCG AGCTCTTTAG AACTCCAGAG GAAGATCCTG 
CCGGGCCTGT ACATTGGCAA CTTCAAAGAT GCAAGAGATG CAGAACAATT GAGCAGGAAC 
AAGGTGACAC ACATTCTTTC TGTGCACGAC ACTGCCAGGC CCATGCTGGA GGGAGTTAAA 
TACCTGTGTA TTCCAGCAGC AGACTCACCG TCTCAAAACC TGACAAGACA TTTCAAAGAA 
AGTATTAAAT TCATTCATGA GTGCCGACTC CAGGGTGAGG GCTGTCTTGT ACATTGCCTG 
GCTGGGGTCT CCAGGAGTGT GACACTGGTG ATCGCATACA TCATGACTGT CACCGACTTT 
GGCTGGGAAG AGGCCTTACA CACCGTTCGT GCAGGGAGGT CCTGTGCCAA CCCCAACCTG 
GGCTTCCAAA GGCAGCTGCA GGAGTTTGAG AAACACGAAG TGCGGCAGTA TCGGCAATGG 
CTGAGAGAAG AATATGGAGA GAACCCCTTG CGGGATGCAG AAGAAGCCAA AAGCATTCTG 
GGTAAATATA AAGAGCAAGG GCGCATGGAG CCCCGGCCTA GCAGCAGGCG GTGGAGCAGC 
CTTTCAGCCC TGCCTGCTCT CACCTACAAT AACTACACAA CAGAGACCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dusp22 ( XM_017600603.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017456092.1 Rattus norvegicus dual specificity phosphatase 22 (Dusp22), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa59092
Clone ID Related Accession (Same CDS sequence)	XM_017600603.1
Accession Version	XM_017600603.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 648bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	dual specificity protein phosphatase 22 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005116.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGAGAT CACATGCTCA TACTAGAGCT GTAAAGTCCC ATGGGAGCTG GTATCTGGCC 
CCTTGCGGCC TATGCAGGAA NGNAGAGTCG AGCTCTTTAG AACTCCAGAG GAAGATCCTG 
CCGGGCCTGT ACATTGGCAA CTTCAAAGAT GCAAGAGATG CAGAACAATT GAGCAGGAAC 
AAGGTGACAC ACATTCTTTC TGTGCACGAC ACTGCCAGGC CCATGCTGGA GGGAGTTAAA 
TACCTGTGTA TTCCAGCAGC AGACTCACCG TCTCAAAACC TGACAAGACA TTTCAAAGAA 
AGTATTAAAT TCATTCATGA GTGCCGACTC CAGGGTGAGG GCTGTCTTGT ACATTGCCTG 
GCTGGGGTCT CCAGGAGTGT GACACTGGTG ATCGCATACA TCATGACTGT CACCGACTTT 
GGCTGGGAAG AGGCCTTACA CACCGTTCGT GCAGGGAGGT CCTGTGCCAA CCCCAACCTG 
GGCTTCCAAA GGCAGCTGCA GGAGTTTGAG AAACACGAAG TGCGGCAGTA TCGGCAATGG 
CTGAGAGAAG AATATGGAGA GAACCCCTTG CGGGATGCAG AAGAAGCCAA AAGCATTCTG 
GCTGCCCCGG GAATTCTGAA GTACTGGGCC TTTCTCAGAA GACTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017456092.1
CDS	5960..6607
Translation	MLRSHAHTRAVKSHGSWYLAPCGLCRnullnullESSSLELQRKILPGLYIGNFKDARDAEQLSRNKVTHILSVHDTARPMLEGVKYLCIPAADSPSQNLTRHFKESIKFIHECRLQGEGCLVHCLAGVSRSVTLVIAYIMTVTDFGWEEALHTVRAGRSCANPNLGFQRQLQEFEKHEVRQYRQWLREEYGENPLRDAEEAKSILAAPGILKYWAFLRRL

Target ORF information:

RefSeq Version	XM_017600603.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual specificity phosphatase 22 (Dusp22), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017600603.1

ORF Insert Sequence:

ATGCTGAGAT CACATGCTCA TACTAGAGCT GTAAAGTCCC ATGGGAGCTG GTATCTGGCC 
CCTTGCGGCC TATGCAGGAA NGNAGAGTCG AGCTCTTTAG AACTCCAGAG GAAGATCCTG 
CCGGGCCTGT ACATTGGCAA CTTCAAAGAT GCAAGAGATG CAGAACAATT GAGCAGGAAC 
AAGGTGACAC ACATTCTTTC TGTGCACGAC ACTGCCAGGC CCATGCTGGA GGGAGTTAAA 
TACCTGTGTA TTCCAGCAGC AGACTCACCG TCTCAAAACC TGACAAGACA TTTCAAAGAA 
AGTATTAAAT TCATTCATGA GTGCCGACTC CAGGGTGAGG GCTGTCTTGT ACATTGCCTG 
GCTGGGGTCT CCAGGAGTGT GACACTGGTG ATCGCATACA TCATGACTGT CACCGACTTT 
GGCTGGGAAG AGGCCTTACA CACCGTTCGT GCAGGGAGGT CCTGTGCCAA CCCCAACCTG 
GGCTTCCAAA GGCAGCTGCA GGAGTTTGAG AAACACGAAG TGCGGCAGTA TCGGCAATGG 
CTGAGAGAAG AATATGGAGA GAACCCCTTG CGGGATGCAG AAGAAGCCAA AAGCATTCTG 
GCTGCCCCGG GAATTCTGAA GTACTGGGCC TTTCTCAGAA GACTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The phosphatase JKAP/DUSP22 inhibits T-cell receptor signalling and autoimmunity by inactivating Lck.
Nature communications53618(2014 Apr)
Li JP,Yang CY,Chuang HC,Lan JL,Chen DY,Chen YM,Wang X,Chen AJ,Belmont JW,Tan TH

JNK pathway-associated phosphatase dephosphorylates focal adhesion kinase and suppresses cell migration.
The Journal of biological chemistry285(8)5472-8(2010 Feb)
Li JP,Fu YN,Chen YR,Tan TH

Regulation of STAT3-mediated signaling by LMW-DSP2.
Oncogene25(42)5801-6(2006 Sep)
Sekine Y,Tsuji S,Ikeda O,Sato N,Aoki N,Aoyama K,Sugiyama K,Matsuda T

The dual specificity JKAP specifically activates the c-Jun N-terminal kinase pathway.
The Journal of biological chemistry277(39)36592-601(2002 Sep)
Chen AJ,Zhou G,Juan T,Colicos SM,Cannon JP,Cabriera-Hansen M,Meyer CF,Jurecic R,Copeland NG,Gilbert DJ,Jenkins NA,Fletcher F,Tan TH,Belmont JW

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Dusp22 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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