Smc6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Smc6
Entrez Gene ID	313961
Full Name	structural maintenance of chromosomes 6
Synonyms	Smc6l1
General protein information	Preferred Names structural maintenance of chromosomes 6 Names structural maintenance of chromosomes protein 6 SMC6 structural maintenance of chromosomes 6-like 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q15

mRNA and Protein(s)

mRNA	Protein	Name
NM_001108014.1	NP_001101484.1	structural maintenance of chromosomes protein 6
XM_006239898.3	XP_006239960.1	structural maintenance of chromosomes protein 6 isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	SMC6	XP_002691521.2
Danio rerio (zebrafish)	si:dkey-119f1.1	NP_001121806.1
Arabidopsis thaliana (thale cress)	SMC6A	NP_196383.1
Oryza sativa (rice)	Os09g0121000	NP_001175716.1
Pan troglodytes (chimpanzee)	SMC6	XP_001136387.1
Arabidopsis thaliana (thale cress)	MIM	NP_200954.1
Xenopus tropicalis (tropical clawed frog)	LOC100496941	XP_002934531.2
Xenopus tropicalis (tropical clawed frog)	LOC100495634	XP_004918255.1
Xenopus tropicalis (tropical clawed frog)	LOC100495796	XP_004918254.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002985	XP_311902.4
Homo sapiens (human)	SMC6	NP_078900.1
Canis lupus familiaris (dog)	SMC6	XP_005630207.1
Gallus gallus (chicken)	SMC6	XP_004935838.1
Mus musculus (house mouse)	Smc6	NP_079971.2
Drosophila melanogaster (fruit fly)	CG5524	NP_651228.1
Rattus norvegicus (Norway rat)	Smc6	NP_001101484.1

Gene Ontology
Bibliography

Related articles in PubMed

DNA repair. Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links.
Räschle M, Smeenk G, Hansen RK, Temu T, Oka Y, Hein MY, Nagaraj N, Long DT, Walter JC, Hofmann K, Storchova Z, Cox J, Bekker-Jensen S, Mailand N, Mann M
Science (New York, N.Y.)348(6234)1253671(2015 May)

Identification of the proteins, including MAGEG1, that make up the human SMC5-6 protein complex.
Taylor EM, Copsey AC, Hudson JJ, Vidot S, Lehmann AR
Molecular and cellular biology28(4)1197-206(2008 Feb)

The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins.
Potts PR, Yu H
Nature structural & molecular biology14(7)581-90(2007 Jul)

Characterization of a novel human SMC heterodimer homologous to the Schizosaccharomyces pombe Rad18/Spr18 complex.
Taylor EM, Moghraby JS, Lees JH, Smit B, Moens PB, Lehmann AR
Molecular biology of the cell12(6)1583-94(2001 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Smc6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Smc6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06496	NM_001108014.1 Latest version!	Rattus norvegicus structural maintenance of chromosomes 6 (Smc6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
ORa06496	XM_006239898.3 Latest version!	Rattus norvegicus structural maintenance of chromosomes 6 (Smc6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Smc6 ( NM_001108014.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101484.1 Rattus norvegicus structural maintenance of chromosomes 6 (Smc6), mRNA.

Price & Availability↑

CloneID	ORa06496
Clone ID Related Accession (Same CDS sequence)	NM_001108014.1 , XM_006239898.3
Accession Version	NM_001108014.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3294bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506787200000
Organism	Rattus norvegicus(Norway rat)
Product	structural maintenance of chromosomes protein 6
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473947.1. On or before Oct 4, 2007 this sequence version replaced XM_233970.4, XM_001068591.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCCAAAA GAAAGGAAGA AAATTTTTGC TCTCCTGAAA ATGCTAAAAG ACCAAGACAG 
GAAGAACTGG AAGATTTTGA TAAAGATGGA GATGAGGATG AATGTACAAT TTCTTTCACA 
AATGGAACCT CCACTTTGAC TGCAGCAGAA GTTGGAATAA TTGAGAGTAT TCAGCTAAGA 
AATTTCATGT GCCATTCAAT GCTTGGACCT TTTAAGTTTG GTTCTAATGT CAACTTTGTG 
GTTGGCAATA ATGGAAGTGG GAAGAGTGCT GTGCTCACTG CACTCATAGT TGGTCTTGGT 
GGAAAAGCAG TTGCTACTAA CAGAGGATCC TCTTTAAAAG GTTTTGTGAA AGCTGGACAG 
AACTCAGCAG ATATCTCAAT AACATTAAGG AACAGAGGAG ATGATGCCTT CAGGGCAAAC 
GTGTATGGTG ACTCCATAGT TGTGCAACAA CACATTAGCG TGGATGGAAG TCGATCTTAC 
AAACTAAAAA GTGAAAAAGG CACCGTGGTT TCTACAAGGA AGGAAGAGCT GATCGCAATT 
CTTGACCATT TTAACATCCA GGTGGATAAT CCAGTTTCCG TTTTAACACA AGAGATGAGC 
AAGCAATTCT TACAATCCAA AAATGAGGGA GACAAATACA AATTCTTCAT GAAAGCAACC 
CAATTGGAAC AGATGAAGGA AGATTATTCA TATATTATGG AAACGAAAGA AAGAACAAAG 
GAGCAAATAA ATCAGGGAGA AGAGCGACTT ACTGAGCTAA AGCGCCAGTG CTTGGAGAAA 
GAGGAACGTT TTCAAAATAT TGCTGGTTTA AGTACAATGA AGACGAATTT AGAGTATTTG 
AAACATGAAA TGGCATGGGC TGTGGTCAAT GAAATTGAAA AACAGTTGAA TGCTATTCGA 
GATAATATCA AAATTGGAGA AGAACGCGCT GCCAAACTTG ACAGGAAAAT GGAAGAGCAG 
CAGGTCAGAC TTAATGATGC AGAAAAAAAA TACAAAGATA TACAAGATAA ACTAGAAAAA 
ATTAGTGAAG AGACAAATGC ACGAGCACCA GAATGTATGG CCTTGAAAAC AGATGTCATT 
GCAAGAACAA GAGCCTTTAA TGATGCTGAG GTTTTATATA ATCGTTCCCT AAATGAATAT 
AAAGCATTAA AAAAAGATGG TGAACAGCTT TGTAAAAGAA TTGAAGAGCT GAAGAAAAGT 
ACCGACCAGT CATTAGAACC AGAGCGATTG GAAAGGCAAA AAAGGATCTG CTGGTTAAAA 
GAGAAAGTAA AGGCCTTACA GGATCAGGAA AATACAGTCA ATCAGGAGGT TGAACAGTTC 
GAGCAAGCCA TAGAAAAGGA CAAACAAGAA CACGTCCGAA TTAAGAGAGA AGATGTAGAA 
GTGAGACATA CACTCAGCTA TAATCAGAGA CAATTGAAAG AACTGAAAGA TAGTAAAACT 
GATCGACTAA AAAGATTTGG TCCTCATGTT CCAGCTCTTC TGGAAGCAAT AGATGATGCT 
TACAGACGGA GACAGTTTAC CCATAAACCT ATTGGCCCTT TAGGTGCTTG CATTCATCTA 
CGGGACCCTG AACTTGCATT GGCCATTGAG TCTTGCTTAA AAGGACTTCT GCAAGCCTAT 
TGCTGCCATA ATCATGCTGA TGAAAGAGTA CTTCAGTCAT TGATGAAAAA GTTTTATCCA 
CCAGGGACCT CTCGACCACA GATAATCGTT TCGGAATTTC GGAATGAGGT ATATGATGTG 
AGACTCAGAG CTGCTTACCA TCCAGAGTTT CCAACTGTTC TGACAGCTTT AGAAATAGAC 
AATGCTGTTG TTGCAAACAG TCTGATTGAC ATGCGGAGCA TAGAGACAGT GCTGCTGATC 
AAAAATAATT CTGTAGCTCG TGCAGTCATG CAGTCCCAAA AGCCACCCAA AAATTGTAGA 
GAAGCTTTTA CTGCTGACGG TGATCAAGTT TTTGCAGGAC GTTATTATTC ATCTGAAAGT 
ACAAGACCCA AGTTTCTAAG CAGAGATGTG GATTCTGAAA TAAGTGACTT GGAAACTGAG 
ATTGAAAATA AAAAGGGCCA CATAATGAAC CTTCAGCACC GTCTGTCTGC TCTTGAGAAG 
GATATTAAAC GCAATGAAGA ACTTCTTAAA AGGTGCCAAC TACATTATAA AGAAATAAAG 
ATGAAAATAA GAAAAAATAT TTCTGAAATT CGGGAACTTG AGAACATAGA AGAACACCAA 
TCTGTAGATA TTGCAACCTT GGAAGATGAA GCGGAGGAAA ATAAAATAAA AATGCAAATG 
GTGGAGAAAA ATATGGAGCA ACAAAAAGAA AACATGGAGA ATCTTAAAAC TCTAAAAATT 
GAAGCAGAAA ACAAGTATGA TACAATTAAA TTGAAGATTA ATCAGCTATC AGAGCTAGCA 
GATCCACTTA AGGATGAATT AAATCTTGCT GACTCTGAAG TGGATAGCCA GAAACGGGGA 
AAGCAGCATT ATGAAGATAA ACAGAAAGAA CATATGGATA CCCTAAATAA AAAGAGAAGA 
GAGCTTGACA TGAAGGAAAA GGAGCTACAG GAGAAAATGT CGCAAGCAAG ACAGATCTGC 
CCAGAACGCA TAGAAGTAAA AAAATCTGCA TCAATTCTAG ACAAAGAAAT TAATCGATTA 
AGACAAAAAA TTCAGGCAGA ACATGCTAGT CATGGAGATC GGGAAGAAAT AATGAAGCAG 
TACCAGGAAG CAAGAGAAAC CTATCTTGAT CTGGATAGTA AAGTAAGGAC TTTAAGAAGG 
TTCATTAAAT TACTTGAAGA AATAATGACC CATAGGTACA AAACATACCA ACAATTTAGA 
AGGTGTCTGA CACTACGATG CAAGTTATAC TTTGACAACT TATTATCTCA GCGTGCTTAT 
TGTGGAAAAA TGAATTTTGA CCACAAGAAT GAAACTCTTA GTATATCAGT TCAGCCCGGA 
GAGGGAAACA AAGCCTCCTT CAATGACATG CGTGCTTTGT CCGGCGGCGA GCGCTCTTTT 
TCCACAGTGT GCTTCATTCT TTCCCTGTGG TCCATTGCTG AATCACCTTT CAGATGCCTG 
GATGAGTTTG ATGTCTACAT GGATATGGTT AATAGGAGAA TTGCGATGGA CATGATCCTT 
AAGATGGCAG ATTCCCAACG TTTTAGACAG TTTATCTTGC TTACCCCTCA AAGCATGAGC 
TCACTTCCTT CAAGTAAACT GATTCGAATT CTTCGAATGT CTGACCCTGA AAGAGGGCAA 
ACCACCTTGC CCTTCCGACC TGTGACTCAA GAAGAAGATG ACAGTGCAAG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101484.1
CDS	130..3423
Translation	MAKRKEENFCSPENAKRPRQEELEDFDKDGDEDECTISFTNGTSTLTAAEVGIIESIQLRNFMCHSMLGPFKFGSNVNFVVGNNGSGKSAVLTALIVGLGGKAVATNRGSSLKGFVKAGQNSADISITLRNRGDDAFRANVYGDSIVVQQHISVDGSRSYKLKSEKGTVVSTRKEELIAILDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYKFFMKATQLEQMKEDYSYIMETKERTKEQINQGEERLTELKRQCLEKEERFQNIAGLSTMKTNLEYLKHEMAWAVVNEIEKQLNAIRDNIKIGEERAAKLDRKMEEQQVRLNDAEKKYKDIQDKLEKISEETNARAPECMALKTDVIARTRAFNDAEVLYNRSLNEYKALKKDGEQLCKRIEELKKSTDQSLEPERLERQKRICWLKEKVKALQDQENTVNQEVEQFEQAIEKDKQEHVRIKREDVEVRHTLSYNQRQLKELKDSKTDRLKRFGPHVPALLEAIDDAYRRRQFTHKPIGPLGACIHLRDPELALAIESCLKGLLQAYCCHNHADERVLQSLMKKFYPPGTSRPQIIVSEFRNEVYDVRLRAAYHPEFPTVLTALEIDNAVVANSLIDMRSIETVLLIKNNSVARAVMQSQKPPKNCREAFTADGDQVFAGRYYSSESTRPKFLSRDVDSEISDLETEIENKKGHIMNLQHRLSALEKDIKRNEELLKRCQLHYKEIKMKIRKNISEIRELENIEEHQSVDIATLEDEAEENKIKMQMVEKNMEQQKENMENLKTLKIEAENKYDTIKLKINQLSELADPLKDELNLADSEVDSQKRGKQHYEDKQKEHMDTLNKKRRELDMKEKELQEKMSQARQICPERIEVKKSASILDKEINRLRQKIQAEHASHGDREEIMKQYQEARETYLDLDSKVRTLRRFIKLLEEIMTHRYKTYQQFRRCLTLRCKLYFDNLLSQRAYCGKMNFDHKNETLSISVQPGEGNKASFNDMRALSGGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDMILKMADSQRFRQFILLTPQSMSSLPSSKLIRILRMSDPERGQTTLPFRPVTQEEDDSAS

Target ORF information:

RefSeq Version	NM_001108014.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus structural maintenance of chromosomes 6 (Smc6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108014.1

ORF Insert Sequence:

ATGGCCAAAA GAAAGGAAGA AAATTTTTGC TCTCCTGAAA ATGCTAAAAG ACCAAGACAG 
GAAGAACTGG AAGATTTTGA TAAAGATGGA GATGAGGATG AATGTACAAT TTCTTTCACA 
AATGGAACCT CCACTTTGAC TGCAGCAGAA GTTGGAATAA TTGAGAGTAT TCAGCTAAGA 
AATTTCATGT GCCATTCAAT GCTTGGACCT TTTAAGTTTG GTTCTAATGT CAACTTTGTG 
GTTGGCAATA ATGGAAGTGG GAAGAGTGCT GTGCTCACTG CACTCATAGT TGGTCTTGGT 
GGAAAAGCAG TTGCTACTAA CAGAGGATCC TCTTTAAAAG GTTTTGTGAA AGCTGGACAG 
AACTCAGCAG ATATCTCAAT AACATTAAGG AACAGAGGAG ATGATGCCTT CAGGGCAAAC 
GTGTATGGTG ACTCCATAGT TGTGCAACAA CACATTAGCG TGGATGGAAG TCGATCTTAC 
AAACTAAAAA GTGAAAAAGG CACCGTGGTT TCTACAAGGA AGGAAGAGCT GATCGCAATT 
CTTGACCATT TTAACATCCA GGTGGATAAT CCAGTTTCCG TTTTAACACA AGAGATGAGC 
AAGCAATTCT TACAATCCAA AAATGAGGGA GACAAATACA AATTCTTCAT GAAAGCAACC 
CAATTGGAAC AGATGAAGGA AGATTATTCA TATATTATGG AAACGAAAGA AAGAACAAAG 
GAGCAAATAA ATCAGGGAGA AGAGCGACTT ACTGAGCTAA AGCGCCAGTG CTTGGAGAAA 
GAGGAACGTT TTCAAAATAT TGCTGGTTTA AGTACAATGA AGACGAATTT AGAGTATTTG 
AAACATGAAA TGGCATGGGC TGTGGTCAAT GAAATTGAAA AACAGTTGAA TGCTATTCGA 
GATAATATCA AAATTGGAGA AGAACGCGCT GCCAAACTTG ACAGGAAAAT GGAAGAGCAG 
CAGGTCAGAC TTAATGATGC AGAAAAAAAA TACAAAGATA TACAAGATAA ACTAGAAAAA 
ATTAGTGAAG AGACAAATGC ACGAGCACCA GAATGTATGG CCTTGAAAAC AGATGTCATT 
GCAAGAACAA GAGCCTTTAA TGATGCTGAG GTTTTATATA ATCGTTCCCT AAATGAATAT 
AAAGCATTAA AAAAAGATGG TGAACAGCTT TGTAAAAGAA TTGAAGAGCT GAAGAAAAGT 
ACCGACCAGT CATTAGAACC AGAGCGATTG GAAAGGCAAA AAAGGATCTG CTGGTTAAAA 
GAGAAAGTAA AGGCCTTACA GGATCAGGAA AATACAGTCA ATCAGGAGGT TGAACAGTTC 
GAGCAAGCCA TAGAAAAGGA CAAACAAGAA CACGTCCGAA TTAAGAGAGA AGATGTAGAA 
GTGAGACATA CACTCAGCTA TAATCAGAGA CAATTGAAAG AACTGAAAGA TAGTAAAACT 
GATCGACTAA AAAGATTTGG TCCTCATGTT CCAGCTCTTC TGGAAGCAAT AGATGATGCT 
TACAGACGGA GACAGTTTAC CCATAAACCT ATTGGCCCTT TAGGTGCTTG CATTCATCTA 
CGGGACCCTG AACTTGCATT GGCCATTGAG TCTTGCTTAA AAGGACTTCT GCAAGCCTAT 
TGCTGCCATA ATCATGCTGA TGAAAGAGTA CTTCAGTCAT TGATGAAAAA GTTTTATCCA 
CCAGGGACCT CTCGACCACA GATAATCGTT TCGGAATTTC GGAATGAGGT ATATGATGTG 
AGACTCAGAG CTGCTTACCA TCCAGAGTTT CCAACTGTTC TGACAGCTTT AGAAATAGAC 
AATGCTGTTG TTGCAAACAG TCTGATTGAC ATGCGGAGCA TAGAGACAGT GCTGCTGATC 
AAAAATAATT CTGTAGCTCG TGCAGTCATG CAGTCCCAAA AGCCACCCAA AAATTGTAGA 
GAAGCTTTTA CTGCTGACGG TGATCAAGTT TTTGCAGGAC GTTATTATTC ATCTGAAAGT 
ACAAGACCCA AGTTTCTAAG CAGAGATGTG GATTCTGAAA TAAGTGACTT GGAAACTGAG 
ATTGAAAATA AAAAGGGCCA CATAATGAAC CTTCAGCACC GTCTGTCTGC TCTTGAGAAG 
GATATTAAAC GCAATGAAGA ACTTCTTAAA AGGTGCCAAC TACATTATAA AGAAATAAAG 
ATGAAAATAA GAAAAAATAT TTCTGAAATT CGGGAACTTG AGAACATAGA AGAACACCAA 
TCTGTAGATA TTGCAACCTT GGAAGATGAA GCGGAGGAAA ATAAAATAAA AATGCAAATG 
GTGGAGAAAA ATATGGAGCA ACAAAAAGAA AACATGGAGA ATCTTAAAAC TCTAAAAATT 
GAAGCAGAAA ACAAGTATGA TACAATTAAA TTGAAGATTA ATCAGCTATC AGAGCTAGCA 
GATCCACTTA AGGATGAATT AAATCTTGCT GACTCTGAAG TGGATAGCCA GAAACGGGGA 
AAGCAGCATT ATGAAGATAA ACAGAAAGAA CATATGGATA CCCTAAATAA AAAGAGAAGA 
GAGCTTGACA TGAAGGAAAA GGAGCTACAG GAGAAAATGT CGCAAGCAAG ACAGATCTGC 
CCAGAACGCA TAGAAGTAAA AAAATCTGCA TCAATTCTAG ACAAAGAAAT TAATCGATTA 
AGACAAAAAA TTCAGGCAGA ACATGCTAGT CATGGAGATC GGGAAGAAAT AATGAAGCAG 
TACCAGGAAG CAAGAGAAAC CTATCTTGAT CTGGATAGTA AAGTAAGGAC TTTAAGAAGG 
TTCATTAAAT TACTTGAAGA AATAATGACC CATAGGTACA AAACATACCA ACAATTTAGA 
AGGTGTCTGA CACTACGATG CAAGTTATAC TTTGACAACT TATTATCTCA GCGTGCTTAT 
TGTGGAAAAA TGAATTTTGA CCACAAGAAT GAAACTCTTA GTATATCAGT TCAGCCCGGA 
GAGGGAAACA AAGCCTCCTT CAATGACATG CGTGCTTTGT CCGGCGGCGA GCGCTCTTTT 
TCCACAGTGT GCTTCATTCT TTCCCTGTGG TCCATTGCTG AATCACCTTT CAGATGCCTG 
GATGAGTTTG ATGTCTACAT GGATATGGTT AATAGGAGAA TTGCGATGGA CATGATCCTT 
AAGATGGCAG ATTCCCAACG TTTTAGACAG TTTATCTTGC TTACCCCTCA AAGCATGAGC 
TCACTTCCTT CAAGTAAACT GATTCGAATT CTTCGAATGT CTGACCCTGA AAGAGGGCAA 
ACCACCTTGC CCTTCCGACC TGTGACTCAA GAAGAAGATG ACAGTGCAAG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Smc6 ( XM_006239898.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006239960.1 Rattus norvegicus structural maintenance of chromosomes 6 (Smc6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa06496
Clone ID Related Accession (Same CDS sequence)	NM_001108014.1 , XM_006239898.3
Accession Version	XM_006239898.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3294bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	structural maintenance of chromosomes protein 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006239898.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCAAAA GAAAGGAAGA AAATTTTTGC TCTCCTGAAA ATGCTAAAAG ACCAAGACAG 
GAAGAACTGG AAGATTTTGA TAAAGATGGA GATGAGGATG AATGTACAAT TTCTTTCACA 
AATGGAACCT CCACTTTGAC TGCAGCAGAA GTTGGAATAA TTGAGAGTAT TCAGCTAAGA 
AATTTCATGT GCCATTCAAT GCTTGGACCT TTTAAGTTTG GTTCTAATGT CAACTTTGTG 
GTTGGCAATA ATGGAAGTGG GAAGAGTGCT GTGCTCACTG CACTCATAGT TGGTCTTGGT 
GGAAAAGCAG TTGCTACTAA CAGAGGATCC TCTTTAAAAG GTTTTGTGAA AGCTGGACAG 
AACTCAGCAG ATATCTCAAT AACATTAAGG AACAGAGGAG ATGATGCCTT CAGGGCAAAC 
GTGTATGGTG ACTCCATAGT TGTGCAACAA CACATTAGCG TGGATGGAAG TCGATCTTAC 
AAACTAAAAA GTGAAAAAGG CACCGTGGTT TCTACAAGGA AGGAAGAGCT GATCGCAATT 
CTTGACCATT TTAACATCCA GGTGGATAAT CCAGTTTCCG TTTTAACACA AGAGATGAGC 
AAGCAATTCT TACAATCCAA AAATGAGGGA GACAAATACA AATTCTTCAT GAAAGCAACC 
CAATTGGAAC AGATGAAGGA AGATTATTCA TATATTATGG AAACGAAAGA AAGAACAAAG 
GAGCAAATAA ATCAGGGAGA AGAGCGACTT ACTGAGCTAA AGCGCCAGTG CTTGGAGAAA 
GAGGAACGTT TTCAAAATAT TGCTGGTTTA AGTACAATGA AGACGAATTT AGAGTATTTG 
AAACATGAAA TGGCATGGGC TGTGGTCAAT GAAATTGAAA AACAGTTGAA TGCTATTCGA 
GATAATATCA AAATTGGAGA AGAACGCGCT GCCAAACTTG ACAGGAAAAT GGAAGAGCAG 
CAGGTCAGAC TTAATGATGC AGAAAAAAAA TACAAAGATA TACAAGATAA ACTAGAAAAA 
ATTAGTGAAG AGACAAATGC ACGAGCACCA GAATGTATGG CCTTGAAAAC AGATGTCATT 
GCAAGAACAA GAGCCTTTAA TGATGCTGAG GTTTTATATA ATCGTTCCCT AAATGAATAT 
AAAGCATTAA AAAAAGATGG TGAACAGCTT TGTAAAAGAA TTGAAGAGCT GAAGAAAAGT 
ACCGACCAGT CATTAGAACC AGAGCGATTG GAAAGGCAAA AAAGGATCTG CTGGTTAAAA 
GAGAAAGTAA AGGCCTTACA GGATCAGGAA AATACAGTCA ATCAGGAGGT TGAACAGTTC 
GAGCAAGCCA TAGAAAAGGA CAAACAAGAA CACGTCCGAA TTAAGAGAGA AGATGTAGAA 
GTGAGACATA CACTCAGCTA TAATCAGAGA CAATTGAAAG AACTGAAAGA TAGTAAAACT 
GATCGACTAA AAAGATTTGG TCCTCATGTT CCAGCTCTTC TGGAAGCAAT AGATGATGCT 
TACAGACGGA GACAGTTTAC CCATAAACCT ATTGGCCCTT TAGGTGCTTG CATTCATCTA 
CGGGACCCTG AACTTGCATT GGCCATTGAG TCTTGCTTAA AAGGACTTCT GCAAGCCTAT 
TGCTGCCATA ATCATGCTGA TGAAAGAGTA CTTCAGTCAT TGATGAAAAA GTTTTATCCA 
CCAGGGACCT CTCGACCACA GATAATCGTT TCGGAATTTC GGAATGAGGT ATATGATGTG 
AGACTCAGAG CTGCTTACCA TCCAGAGTTT CCAACTGTTC TGACAGCTTT AGAAATAGAC 
AATGCTGTTG TTGCAAACAG TCTGATTGAC ATGCGGAGCA TAGAGACAGT GCTGCTGATC 
AAAAATAATT CTGTAGCTCG TGCAGTCATG CAGTCCCAAA AGCCACCCAA AAATTGTAGA 
GAAGCTTTTA CTGCTGACGG TGATCAAGTT TTTGCAGGAC GTTATTATTC ATCTGAAAGT 
ACAAGACCCA AGTTTCTAAG CAGAGATGTG GATTCTGAAA TAAGTGACTT GGAAACTGAG 
ATTGAAAATA AAAAGGGCCA CATAATGAAC CTTCAGCACC GTCTGTCTGC TCTTGAGAAG 
GATATTAAAC GCAATGAAGA ACTTCTTAAA AGGTGCCAAC TACATTATAA AGAAATAAAG 
ATGAAAATAA GAAAAAATAT TTCTGAAATT CGGGAACTTG AGAACATAGA AGAACACCAA 
TCTGTAGATA TTGCAACCTT GGAAGATGAA GCGGAGGAAA ATAAAATAAA AATGCAAATG 
GTGGAGAAAA ATATGGAGCA ACAAAAAGAA AACATGGAGA ATCTTAAAAC TCTAAAAATT 
GAAGCAGAAA ACAAGTATGA TACAATTAAA TTGAAGATTA ATCAGCTATC AGAGCTAGCA 
GATCCACTTA AGGATGAATT AAATCTTGCT GACTCTGAAG TGGATAGCCA GAAACGGGGA 
AAGCAGCATT ATGAAGATAA ACAGAAAGAA CATATGGATA CCCTAAATAA AAAGAGAAGA 
GAGCTTGACA TGAAGGAAAA GGAGCTACAG GAGAAAATGT CGCAAGCAAG ACAGATCTGC 
CCAGAACGCA TAGAAGTAAA AAAATCTGCA TCAATTCTAG ACAAAGAAAT TAATCGATTA 
AGACAAAAAA TTCAGGCAGA ACATGCTAGT CATGGAGATC GGGAAGAAAT AATGAAGCAG 
TACCAGGAAG CAAGAGAAAC CTATCTTGAT CTGGATAGTA AAGTAAGGAC TTTAAGAAGG 
TTCATTAAAT TACTTGAAGA AATAATGACC CATAGGTACA AAACATACCA ACAATTTAGA 
AGGTGTCTGA CACTACGATG CAAGTTATAC TTTGACAACT TATTATCTCA GCGTGCTTAT 
TGTGGAAAAA TGAATTTTGA CCACAAGAAT GAAACTCTTA GTATATCAGT TCAGCCCGGA 
GAGGGAAACA AAGCCTCCTT CAATGACATG CGTGCTTTGT CCGGCGGCGA GCGCTCTTTT 
TCCACAGTGT GCTTCATTCT TTCCCTGTGG TCCATTGCTG AATCACCTTT CAGATGCCTG 
GATGAGTTTG ATGTCTACAT GGATATGGTT AATAGGAGAA TTGCGATGGA CATGATCCTT 
AAGATGGCAG ATTCCCAACG TTTTAGACAG TTTATCTTGC TTACCCCTCA AAGCATGAGC 
TCACTTCCTT CAAGTAAACT GATTCGAATT CTTCGAATGT CTGACCCTGA AAGAGGGCAA 
ACCACCTTGC CCTTCCGACC TGTGACTCAA GAAGAAGATG ACAGTGCAAG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006239960.1
CDS	96..3389
Translation	MAKRKEENFCSPENAKRPRQEELEDFDKDGDEDECTISFTNGTSTLTAAEVGIIESIQLRNFMCHSMLGPFKFGSNVNFVVGNNGSGKSAVLTALIVGLGGKAVATNRGSSLKGFVKAGQNSADISITLRNRGDDAFRANVYGDSIVVQQHISVDGSRSYKLKSEKGTVVSTRKEELIAILDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYKFFMKATQLEQMKEDYSYIMETKERTKEQINQGEERLTELKRQCLEKEERFQNIAGLSTMKTNLEYLKHEMAWAVVNEIEKQLNAIRDNIKIGEERAAKLDRKMEEQQVRLNDAEKKYKDIQDKLEKISEETNARAPECMALKTDVIARTRAFNDAEVLYNRSLNEYKALKKDGEQLCKRIEELKKSTDQSLEPERLERQKRICWLKEKVKALQDQENTVNQEVEQFEQAIEKDKQEHVRIKREDVEVRHTLSYNQRQLKELKDSKTDRLKRFGPHVPALLEAIDDAYRRRQFTHKPIGPLGACIHLRDPELALAIESCLKGLLQAYCCHNHADERVLQSLMKKFYPPGTSRPQIIVSEFRNEVYDVRLRAAYHPEFPTVLTALEIDNAVVANSLIDMRSIETVLLIKNNSVARAVMQSQKPPKNCREAFTADGDQVFAGRYYSSESTRPKFLSRDVDSEISDLETEIENKKGHIMNLQHRLSALEKDIKRNEELLKRCQLHYKEIKMKIRKNISEIRELENIEEHQSVDIATLEDEAEENKIKMQMVEKNMEQQKENMENLKTLKIEAENKYDTIKLKINQLSELADPLKDELNLADSEVDSQKRGKQHYEDKQKEHMDTLNKKRRELDMKEKELQEKMSQARQICPERIEVKKSASILDKEINRLRQKIQAEHASHGDREEIMKQYQEARETYLDLDSKVRTLRRFIKLLEEIMTHRYKTYQQFRRCLTLRCKLYFDNLLSQRAYCGKMNFDHKNETLSISVQPGEGNKASFNDMRALSGGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDMILKMADSQRFRQFILLTPQSMSSLPSSKLIRILRMSDPERGQTTLPFRPVTQEEDDSAS

Target ORF information:

RefSeq Version	XM_006239898.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus structural maintenance of chromosomes 6 (Smc6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006239898.3

ORF Insert Sequence:

ATGGCCAAAA GAAAGGAAGA AAATTTTTGC TCTCCTGAAA ATGCTAAAAG ACCAAGACAG 
GAAGAACTGG AAGATTTTGA TAAAGATGGA GATGAGGATG AATGTACAAT TTCTTTCACA 
AATGGAACCT CCACTTTGAC TGCAGCAGAA GTTGGAATAA TTGAGAGTAT TCAGCTAAGA 
AATTTCATGT GCCATTCAAT GCTTGGACCT TTTAAGTTTG GTTCTAATGT CAACTTTGTG 
GTTGGCAATA ATGGAAGTGG GAAGAGTGCT GTGCTCACTG CACTCATAGT TGGTCTTGGT 
GGAAAAGCAG TTGCTACTAA CAGAGGATCC TCTTTAAAAG GTTTTGTGAA AGCTGGACAG 
AACTCAGCAG ATATCTCAAT AACATTAAGG AACAGAGGAG ATGATGCCTT CAGGGCAAAC 
GTGTATGGTG ACTCCATAGT TGTGCAACAA CACATTAGCG TGGATGGAAG TCGATCTTAC 
AAACTAAAAA GTGAAAAAGG CACCGTGGTT TCTACAAGGA AGGAAGAGCT GATCGCAATT 
CTTGACCATT TTAACATCCA GGTGGATAAT CCAGTTTCCG TTTTAACACA AGAGATGAGC 
AAGCAATTCT TACAATCCAA AAATGAGGGA GACAAATACA AATTCTTCAT GAAAGCAACC 
CAATTGGAAC AGATGAAGGA AGATTATTCA TATATTATGG AAACGAAAGA AAGAACAAAG 
GAGCAAATAA ATCAGGGAGA AGAGCGACTT ACTGAGCTAA AGCGCCAGTG CTTGGAGAAA 
GAGGAACGTT TTCAAAATAT TGCTGGTTTA AGTACAATGA AGACGAATTT AGAGTATTTG 
AAACATGAAA TGGCATGGGC TGTGGTCAAT GAAATTGAAA AACAGTTGAA TGCTATTCGA 
GATAATATCA AAATTGGAGA AGAACGCGCT GCCAAACTTG ACAGGAAAAT GGAAGAGCAG 
CAGGTCAGAC TTAATGATGC AGAAAAAAAA TACAAAGATA TACAAGATAA ACTAGAAAAA 
ATTAGTGAAG AGACAAATGC ACGAGCACCA GAATGTATGG CCTTGAAAAC AGATGTCATT 
GCAAGAACAA GAGCCTTTAA TGATGCTGAG GTTTTATATA ATCGTTCCCT AAATGAATAT 
AAAGCATTAA AAAAAGATGG TGAACAGCTT TGTAAAAGAA TTGAAGAGCT GAAGAAAAGT 
ACCGACCAGT CATTAGAACC AGAGCGATTG GAAAGGCAAA AAAGGATCTG CTGGTTAAAA 
GAGAAAGTAA AGGCCTTACA GGATCAGGAA AATACAGTCA ATCAGGAGGT TGAACAGTTC 
GAGCAAGCCA TAGAAAAGGA CAAACAAGAA CACGTCCGAA TTAAGAGAGA AGATGTAGAA 
GTGAGACATA CACTCAGCTA TAATCAGAGA CAATTGAAAG AACTGAAAGA TAGTAAAACT 
GATCGACTAA AAAGATTTGG TCCTCATGTT CCAGCTCTTC TGGAAGCAAT AGATGATGCT 
TACAGACGGA GACAGTTTAC CCATAAACCT ATTGGCCCTT TAGGTGCTTG CATTCATCTA 
CGGGACCCTG AACTTGCATT GGCCATTGAG TCTTGCTTAA AAGGACTTCT GCAAGCCTAT 
TGCTGCCATA ATCATGCTGA TGAAAGAGTA CTTCAGTCAT TGATGAAAAA GTTTTATCCA 
CCAGGGACCT CTCGACCACA GATAATCGTT TCGGAATTTC GGAATGAGGT ATATGATGTG 
AGACTCAGAG CTGCTTACCA TCCAGAGTTT CCAACTGTTC TGACAGCTTT AGAAATAGAC 
AATGCTGTTG TTGCAAACAG TCTGATTGAC ATGCGGAGCA TAGAGACAGT GCTGCTGATC 
AAAAATAATT CTGTAGCTCG TGCAGTCATG CAGTCCCAAA AGCCACCCAA AAATTGTAGA 
GAAGCTTTTA CTGCTGACGG TGATCAAGTT TTTGCAGGAC GTTATTATTC ATCTGAAAGT 
ACAAGACCCA AGTTTCTAAG CAGAGATGTG GATTCTGAAA TAAGTGACTT GGAAACTGAG 
ATTGAAAATA AAAAGGGCCA CATAATGAAC CTTCAGCACC GTCTGTCTGC TCTTGAGAAG 
GATATTAAAC GCAATGAAGA ACTTCTTAAA AGGTGCCAAC TACATTATAA AGAAATAAAG 
ATGAAAATAA GAAAAAATAT TTCTGAAATT CGGGAACTTG AGAACATAGA AGAACACCAA 
TCTGTAGATA TTGCAACCTT GGAAGATGAA GCGGAGGAAA ATAAAATAAA AATGCAAATG 
GTGGAGAAAA ATATGGAGCA ACAAAAAGAA AACATGGAGA ATCTTAAAAC TCTAAAAATT 
GAAGCAGAAA ACAAGTATGA TACAATTAAA TTGAAGATTA ATCAGCTATC AGAGCTAGCA 
GATCCACTTA AGGATGAATT AAATCTTGCT GACTCTGAAG TGGATAGCCA GAAACGGGGA 
AAGCAGCATT ATGAAGATAA ACAGAAAGAA CATATGGATA CCCTAAATAA AAAGAGAAGA 
GAGCTTGACA TGAAGGAAAA GGAGCTACAG GAGAAAATGT CGCAAGCAAG ACAGATCTGC 
CCAGAACGCA TAGAAGTAAA AAAATCTGCA TCAATTCTAG ACAAAGAAAT TAATCGATTA 
AGACAAAAAA TTCAGGCAGA ACATGCTAGT CATGGAGATC GGGAAGAAAT AATGAAGCAG 
TACCAGGAAG CAAGAGAAAC CTATCTTGAT CTGGATAGTA AAGTAAGGAC TTTAAGAAGG 
TTCATTAAAT TACTTGAAGA AATAATGACC CATAGGTACA AAACATACCA ACAATTTAGA 
AGGTGTCTGA CACTACGATG CAAGTTATAC TTTGACAACT TATTATCTCA GCGTGCTTAT 
TGTGGAAAAA TGAATTTTGA CCACAAGAAT GAAACTCTTA GTATATCAGT TCAGCCCGGA 
GAGGGAAACA AAGCCTCCTT CAATGACATG CGTGCTTTGT CCGGCGGCGA GCGCTCTTTT 
TCCACAGTGT GCTTCATTCT TTCCCTGTGG TCCATTGCTG AATCACCTTT CAGATGCCTG 
GATGAGTTTG ATGTCTACAT GGATATGGTT AATAGGAGAA TTGCGATGGA CATGATCCTT 
AAGATGGCAG ATTCCCAACG TTTTAGACAG TTTATCTTGC TTACCCCTCA AAGCATGAGC 
TCACTTCCTT CAAGTAAACT GATTCGAATT CTTCGAATGT CTGACCCTGA AAGAGGGCAA 
ACCACCTTGC CCTTCCGACC TGTGACTCAA GAAGAAGATG ACAGTGCAAG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

DNA repair. Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links.
Science (New York, N.Y.)348(6234)1253671(2015 May)
Räschle M,Smeenk G,Hansen RK,Temu T,Oka Y,Hein MY,Nagaraj N,Long DT,Walter JC,Hofmann K,Storchova Z,Cox J,Bekker-Jensen S,Mailand N,Mann M

Identification of the proteins, including MAGEG1, that make up the human SMC5-6 protein complex.
Molecular and cellular biology28(4)1197-206(2008 Feb)
Taylor EM,Copsey AC,Hudson JJ,Vidot S,Lehmann AR

The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins.
Nature structural & molecular biology14(7)581-90(2007 Jul)
Potts PR,Yu H

Characterization of a novel human SMC heterodimer homologous to the Schizosaccharomyces pombe Rad18/Spr18 complex.
Molecular biology of the cell12(6)1583-94(2001 Jun)
Taylor EM,Moghraby JS,Lees JH,Smit B,Moens PB,Lehmann AR

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Smc6 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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