| Gene Symbol | Grwd1 |
| Entrez Gene ID | 308592 |
| Full Name | glutamate-rich WD repeat containing 1 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
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Grwd1 cDNA ORF clone, Rattus norvegicus(Norway rat)
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Gene
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Clones
gRNAs
The following Grwd1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Grwd1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID ORa02148 Clone ID Related Accession (Same CDS sequence) NM_001012067.1 Accession Version NM_001012067.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1338bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1550246400000 Organism Rattus norvegicus(Norway rat) Product glutamate-rich WD repeat-containing protein 1 Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC083883.1. On Feb 11, 2005 this sequence version replaced XM_218563.2. ##Evidence-Data-START## Transcript exon combination :: BC083883.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321ATGGCGGCGC GCAAGGGCCG GAGGCACACA TGTGAAACCG GGGAGCCCAT GGAGGCTGAA
ACCTACGATC TAGGATCCGA AGGCCCATCC CAGGTCTACC TGCCCGGCAG AGGGCCGCCA
CTAGGAGAAG GGGAGGAGCT GGTAATGGAT GAAGAGGCCT ACGTGCTATA CCATCGTGCG
CAAACTGGCG CCCCTTGTCT CAGCTTTGAC ATAGTCCGAG ATCACCTGGG CGACAACCGG
ACAGAGCTCC CTCTCAGTCT TTACCTGTGT GCGGGAACCC AGGCGGAGAG CGCCCAGAGC
AATAGACTGA TGATGCTTCG GATGCACAAT CTCCATGGGA CCAGGCCGCC ACCCTCAGAG
GGCAGTGATG ATGAGGATGA TGAAGATGAA GAGGATGAAG AGGAGCGGAA ACCTCAACTG
GAGCTGGCCA TGGTTCCCCA CTATGGTGGC ATCAACCGAG TTCGGGTATC TTGGCTGGGA
GAGGAGCCCG TGGCTGGAGT ATGGTCAGAG AAGGGCCAGG TGGAGGTGTT TGCACTGCGA
CGGCTCCTGC AGGTGGTGGA TGACCCGCAG GCCCTGGCCA TCTTCCTCCG CGATGAGCAG
GCCCGAGTAA AGCCCATCTT CTCCTTTGCT GGCCACATGG GTGAGGGCTT TGCTCTTGAC
TGGTCCCCTC GGGTACCCGG CCGCTTGTTG ACTGGTGACT GTCAGAAGAA CATCCATCTC
TGGACACCCA CGGATGGTGG TTCCTGGAAT GTGGACCAGA GGCCATTTGT GGGCCATACA
CGCTCTGTGG AGGATCTGCA GTGGTCGCCA ACAGAGGACA CGGTGTTTGC CTCGTGCTCT
GCGGATGCCT CCATTCGCAT CTGGGACATC CGAGCAGCCC CAGGCAAGGC CTGCATGCTC
ACCACAGCCG CTGCCCATGA TGGGGATGTC AACGTCATCA GTTGGAGCCG CAGGGAACCC
TTCCTGCTCA GTGGTGGGGA TGATGGGACC CTCAAAGTCT GGGACCTGCG ACAGTTCAAG
TCTGGCTCCC CTGTGGCCAC CTTCAAGCAA CACGTGGCCC CCGTGACCTC CGTTGAATGG
CACCCTCAGG ACAGTGGGGT CTTTGCAGCC TCAGGTGCTG ACAACCAGAT CACACAGTGG
GACCTGGCAG TTGAGCGGGA CCCAGAGTCA GGTGAGACAG AGACAGACCC TGGGCTGGCG
GCACTGCCCC AGCAGTTGCT GTTCGTGCAT CAAGGTGAGA CTGACCTGAA GGAGCTACAC
TGGCACCCAC AGTGCCCTGG GGTCCTGATC AGCACCGCCC TGTCAGGCTT CACCGTCTTC
AGGACCATCA GTGTTTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_001012067.1 CDS 56..1393 Translation 
Target ORF information:
RefSeq Version NM_001012067.1 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus glutamate-rich WD repeat containing 1 (Grwd1), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_001012067.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321ATGGCGGCGC GCAAGGGCCG GAGGCACACA TGTGAAACCG GGGAGCCCAT GGAGGCTGAA
ACCTACGATC TAGGATCCGA AGGCCCATCC CAGGTCTACC TGCCCGGCAG AGGGCCGCCA
CTAGGAGAAG GGGAGGAGCT GGTAATGGAT GAAGAGGCCT ACGTGCTATA CCATCGTGCG
CAAACTGGCG CCCCTTGTCT CAGCTTTGAC ATAGTCCGAG ATCACCTGGG CGACAACCGG
ACAGAGCTCC CTCTCAGTCT TTACCTGTGT GCGGGAACCC AGGCGGAGAG CGCCCAGAGC
AATAGACTGA TGATGCTTCG GATGCACAAT CTCCATGGGA CCAGGCCGCC ACCCTCAGAG
GGCAGTGATG ATGAGGATGA TGAAGATGAA GAGGATGAAG AGGAGCGGAA ACCTCAACTG
GAGCTGGCCA TGGTTCCCCA CTATGGTGGC ATCAACCGAG TTCGGGTATC TTGGCTGGGA
GAGGAGCCCG TGGCTGGAGT ATGGTCAGAG AAGGGCCAGG TGGAGGTGTT TGCACTGCGA
CGGCTCCTGC AGGTGGTGGA TGACCCGCAG GCCCTGGCCA TCTTCCTCCG CGATGAGCAG
GCCCGAGTAA AGCCCATCTT CTCCTTTGCT GGCCACATGG GTGAGGGCTT TGCTCTTGAC
TGGTCCCCTC GGGTACCCGG CCGCTTGTTG ACTGGTGACT GTCAGAAGAA CATCCATCTC
TGGACACCCA CGGATGGTGG TTCCTGGAAT GTGGACCAGA GGCCATTTGT GGGCCATACA
CGCTCTGTGG AGGATCTGCA GTGGTCGCCA ACAGAGGACA CGGTGTTTGC CTCGTGCTCT
GCGGATGCCT CCATTCGCAT CTGGGACATC CGAGCAGCCC CAGGCAAGGC CTGCATGCTC
ACCACAGCCG CTGCCCATGA TGGGGATGTC AACGTCATCA GTTGGAGCCG CAGGGAACCC
TTCCTGCTCA GTGGTGGGGA TGATGGGACC CTCAAAGTCT GGGACCTGCG ACAGTTCAAG
TCTGGCTCCC CTGTGGCCAC CTTCAAGCAA CACGTGGCCC CCGTGACCTC CGTTGAATGG
CACCCTCAGG ACAGTGGGGT CTTTGCAGCC TCAGGTGCTG ACAACCAGAT CACACAGTGG
GACCTGGCAG TTGAGCGGGA CCCAGAGTCA GGTGAGACAG AGACAGACCC TGGGCTGGCG
GCACTGCCCC AGCAGTTGCT GTTCGTGCAT CAAGGTGAGA CTGACCTGAA GGAGCTACAC
TGGCACCCAC AGTGCCCTGG GGTCCTGATC AGCACCGCCC TGTCAGGCTT CACCGTCTTC
AGGACCATCA GTGTTTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Nucleosome assembly and disassembly activity of GRWD1, a novel Cdt1-binding protein that promotes pre-replication complex formation.
Biochimica et biophysica acta1863(11)2739-2748(2016 11)
Aizawa M,Sugimoto N,Watanabe S,Yoshida K,Fujita M
Cdt1-binding protein GRWD1 is a novel histone-binding protein that facilitates MCM loading through its influence on chromatin architecture.
Nucleic acids research43(12)5898-911(2015 Jul)
Sugimoto N,Maehara K,Yoshida K,Yasukouchi S,Osano S,Watanabe S,Aizawa M,Yugawa T,Kiyono T,Kurumizaka H,Ohkawa Y,Fujita M
A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity.
PLoS genetics9(1)e1003210(2013)
Cloutier P,Lavallée-Adam M,Faubert D,Blanchette M,Coulombe B
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanhäusser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M
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