| Gene Symbol | Klk12 |
| Entrez Gene ID | 308564 |
| Full Name | kallikrein related-peptidase 12 |
| Synonyms | Klnk |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
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Klk12 cDNA ORF clone, Rattus norvegicus(Norway rat)
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Gene
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Clones
gRNAs
The following Klk12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Klk12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID ORa11277 Clone ID Related Accession (Same CDS sequence) NM_001107508.1 Accession Version NM_001107508.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 543bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1527350400000 Organism Rattus norvegicus(Norway rat) Product kallikrein-12 Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473979.2. On or before Oct 4, 2007 this sequence version replaced XM_218644.4, XM_001080413.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA2689600, SAMN02642690 [ECO:0000350] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541ATGGTGCGCC TTGGGGAACA CAGTCTCTCC AAGCTGGATT TGACGGAACA GTTGAGACTC
ACCACCTTCT CCATAACACA CCCCAGCTAC CATGGTGCCT ATCAGAACCA TGAGCATGAT
CTTCGACTCC TACGGCTGAA CAGACCCATC AGCTTGACCT ATGCTGTCCG GCCCGTGGCC
CTGCCCAGTT CCTGTGCACC CACTGGGGCC AAGTGTCATA TATCAGGATG GGGTACTACA
AACAAGCCGT GGGACCCATT CCCAGATCGG CTCCAGTGCC TCGACCTCTC CATTGTCTCT
AACGAGACGT GCCGGGCCGT ATTTCCTGGA AGAGTGACAG AGAACATGTT GTGTGCAGGT
GGAGAAGCCG GAAAGGATGC CTGTCAGGGT GACTCTGGAG GCCCCCTGGT GTGTGGAGGG
GTTCTTCAAG GTCTGGTTTC CTGGGGATCT GTTGGGCCTT GTGGTCAAAA AGGCATCCCA
GGGGTCTACA CCAAGGTCTG CAAATACACG GACTGGATCA GAGTAGTCAT CAGGAACAAC
TAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_001100978.1 CDS 164..706 Translation 
Target ORF information:
RefSeq Version NM_001107508.1 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus kallikrein related-peptidase 12 (Klk12), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_001107508.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541ATGGTGCGCC TTGGGGAACA CAGTCTCTCC AAGCTGGATT TGACGGAACA GTTGAGACTC
ACCACCTTCT CCATAACACA CCCCAGCTAC CATGGTGCCT ATCAGAACCA TGAGCATGAT
CTTCGACTCC TACGGCTGAA CAGACCCATC AGCTTGACCT ATGCTGTCCG GCCCGTGGCC
CTGCCCAGTT CCTGTGCACC CACTGGGGCC AAGTGTCATA TATCAGGATG GGGTACTACA
AACAAGCCGT GGGACCCATT CCCAGATCGG CTCCAGTGCC TCGACCTCTC CATTGTCTCT
AACGAGACGT GCCGGGCCGT ATTTCCTGGA AGAGTGACAG AGAACATGTT GTGTGCAGGT
GGAGAAGCCG GAAAGGATGC CTGTCAGGGT GACTCTGGAG GCCCCCTGGT GTGTGGAGGG
GTTCTTCAAG GTCTGGTTTC CTGGGGATCT GTTGGGCCTT GTGGTCAAAA AGGCATCCCA
GGGGTCTACA CCAAGGTCTG CAAATACACG GACTGGATCA GAGTAGTCAT CAGGAACAAC
TAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID ORa22716 Clone ID Related Accession (Same CDS sequence) XM_008759351.1 Accession Version XM_008759351.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 744bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1469376000000 Organism Rattus norvegicus(Norway rat) Product kallikrein-12 isoform X1 Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##
1
61
121
181
241
301
361
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541
601
661
721ATGAAGCTCA ACATTCTCTT GCTCCTGTGT GTTGTAGGCC TCAGTCAGGC AGACAGGGAG
AAGATCTATA ATGGCGTTGA GTGTGTGAAG AACTCACAGC CTTGGCAGGT GGGGCTGTTC
CATGGCAAAT ACCTGCGCTG TGGTGGTGTC CTCGTGGACC GCAAGTGGGT CCTTACGGCT
GCTCACTGCA GTGGCAAGTA CATGGTGCGC CTTGGGGAAC ACAGTCTCTC CAAGCTGGAT
TTGACGGAAC AGTTGAGACT CACCACCTTC TCCATAACAC ACCCCAGCTA CCATGGTGCC
TATCAGAACC ATGAGCATGA TCTTCGACTC CTACGGCTGA ACAGACCCAT CAGCTTGACC
TATGCTGTCC GGCCCGTGGC CCTGCCCAGT TCCTGTGCAC CCACTGGGGC CAAGTGTCAT
ATATCAGGAT GGGGTACTAC AAACAAGCCG TGGGACCCAT TCCCAGATCG GCTCCAGTGC
CTCGACCTCT CCATTGTCTC TAACGAGACG TGCCGGGCCG TATTTCCTGG AAGAGTGACA
GAGAACATGT TGTGTGCAGG TGGAGAAGCC GGAAAGGATG CCTGTCAGGG TGACTCTGGA
GGCCCCCTGG TGTGTGGAGG GGTTCTTCAA GGTCTGGTTT CCTGGGGATC TGTTGGGCCT
TGTGGTCAAA AAGGCATCCC AGGGGTCTAC ACCAAGGTCT GCAAATACAC GGACTGGATC
AGAGTAGTCA TCAGGAACAA CTAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq XP_008757573.1 CDS 43..786 Translation
Target ORF information:
RefSeq Version XM_008759351.1 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus kallikrein related-peptidase 12 (Klk12), transcript variant X1, mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK XM_008759351.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721ATGAAGCTCA ACATTCTCTT GCTCCTGTGT GTTGTAGGCC TCAGTCAGGC AGACAGGGAG
AAGATCTATA ATGGCGTTGA GTGTGTGAAG AACTCACAGC CTTGGCAGGT GGGGCTGTTC
CATGGCAAAT ACCTGCGCTG TGGTGGTGTC CTCGTGGACC GCAAGTGGGT CCTTACGGCT
GCTCACTGCA GTGGCAAGTA CATGGTGCGC CTTGGGGAAC ACAGTCTCTC CAAGCTGGAT
TTGACGGAAC AGTTGAGACT CACCACCTTC TCCATAACAC ACCCCAGCTA CCATGGTGCC
TATCAGAACC ATGAGCATGA TCTTCGACTC CTACGGCTGA ACAGACCCAT CAGCTTGACC
TATGCTGTCC GGCCCGTGGC CCTGCCCAGT TCCTGTGCAC CCACTGGGGC CAAGTGTCAT
ATATCAGGAT GGGGTACTAC AAACAAGCCG TGGGACCCAT TCCCAGATCG GCTCCAGTGC
CTCGACCTCT CCATTGTCTC TAACGAGACG TGCCGGGCCG TATTTCCTGG AAGAGTGACA
GAGAACATGT TGTGTGCAGG TGGAGAAGCC GGAAAGGATG CCTGTCAGGG TGACTCTGGA
GGCCCCCTGG TGTGTGGAGG GGTTCTTCAA GGTCTGGTTT CCTGGGGATC TGTTGGGCCT
TGTGGTCAAA AAGGCATCCC AGGGGTCTAC ACCAAGGTCT GCAAATACAC GGACTGGATC
AGAGTAGTCA TCAGGAACAA CTAAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Kallikrein-related peptidase 12 hydrolyzes matricellular proteins of the CCN family and modifies interactions of CCN1 and CCN5 with growth factors.
The Journal of biological chemistry286(29)25505-18(2011 Jul)
Guillon-Munos A,Oikonomopoulou K,Michel N,Smith CR,Petit-Courty A,Canepa S,Reverdiau P,Heuzé-Vourc'h N,Diamandis EP,Courty Y
Klk1 as one of the genes contributing to hypertension in Dahl salt-sensitive rat.
Hypertension (Dallas, Tex. : 1979)45(5)947-53(2005 May)
Iwai N,Yasui N,Naraba H,Tago N,Yamawaki H,Sumiya H
Splice-site genetic polymorphism of the human kallikrein 12 (KLK12) gene correlates with no substantial expression of KLK12 protein having serine protease activity.
Human mutation24(3)273-4(2004 Sep)
Shinmura K,Tao H,Yamada H,Kataoka H,Sanjar R,Wang J,Yoshimura K,Sugimura H
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