Kat6a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kat6a
Entrez Gene ID	306571
Full Name	lysine acetyltransferase 6A
Synonyms	Moz,Myst3,Runxbp2,Znf220
General protein information	Preferred Names lysine acetyltransferase 6A Names histone acetyltransferase KAT6A K(lysine) acetyltransferase 6A MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3 MYST histone acetyltransferase (monocytic leukemia) 3 MYST protein 3 MYST-3 histone acetyltransferase MYST3 monocytic leukemia zinc finger homolog monocytic leukemia zinc finger protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 16 Map Location: 16q12.5

mRNA and Protein(s)

mRNA	Protein	Name
NM_001100570.2	NP_001094040.1	histone acetyltransferase KAT6A

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	MYST3	XP_001140373.1
Canis lupus familiaris (dog)	KAT6A	XP_005629865.1
Bos taurus (cattle)	KAT6A	XP_002698753.1
Macaca mulatta (Rhesus monkey)	MYST3	XP_001094798.2
Mus musculus (house mouse)	Kat6a	NP_001074618.1
Homo sapiens (human)	KAT6A	NP_001092882.1
Gallus gallus (chicken)	KAT6A	XP_424402.3
Rattus norvegicus (Norway rat)	Kat6a	NP_001094040.1

Gene Ontology
Bibliography

Related articles in PubMed

KAT6A, a chromatin modifier from the 8p11-p12 amplicon is a candidate oncogene in luminal breast cancer.
Turner-Ivey B, Guest ST, Irish JC, Kappler CS, Garrett-Mayer E, Wilson RC, Ethier SP
Neoplasia (New York, N.Y.)16(8)644-55(2014 Aug)

The leucine twenty homeobox (LEUTX) gene, which lacks a histone acetyltransferase domain, is fused to KAT6A in therapy-related acute myeloid leukemia with t(8;19)(p11;q13).
Chinen Y, Taki T, Tsutsumi Y, Kobayashi S, Matsumoto Y, Sakamoto N, Kuroda J, Horiike S, Nishida K, Ohno H, Uike N, Taniwaki M
Genes, chromosomes & cancer53(4)299-308(2014 Apr)

MOZ increases p53 acetylation and premature senescence through its complex formation with PML.
Rokudai S, Laptenko O, Arnal SM, Taya Y, Kitabayashi I, Prives C
Proceedings of the National Academy of Sciences of the United States of America110(10)3895-900(2013 Mar)

MOZ regulates the Tbx1 locus, and Moz mutation partially phenocopies DiGeorge syndrome.
Voss AK, Vanyai HK, Collin C, Dixon MP, McLennan TJ, Sheikh BN, Scambler P, Thomas T
Developmental cell23(3)652-63(2012 Sep)

Physical and functional HAT/HDAC interplay regulates protein acetylation balance.
Peserico A, Simone C
Journal of biomedicine & biotechnology2011371832(2011)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Kat6a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kat6a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa46428	NM_001100570.2 Latest version!	Rattus norvegicus lysine acetyltransferase 6A (Kat6a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$951.30 $1359.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kat6a ( NM_001100570.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001094040.1 Rattus norvegicus lysine acetyltransferase 6A (Kat6a), mRNA.

Price & Availability↑

CloneID	ORa46428
Clone ID Related Accession (Same CDS sequence)	NM_001100570.2
Accession Version	NM_001100570.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5997bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Rattus norvegicus(Norway rat)
Product	histone acetyltransferase KAT6A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07026361.1 and AB195309.1. On Sep 23, 2014 this sequence version replaced NM_001100570.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB195309.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTAAAGC TCGCTAACCC GCTGTACACG CAGTGGATTT TGGAGGCCAT CAAAAAAGTC 
AAGAAGCAGA AACAGCGACC TTCAGAAGAA AGAATATGCA ATGCAGTGTC GTCCTCCCAC 
GGCTTAGATC GGAAAACTGT CCTGGAGCAG TTGGAGCTGA GTGTTAAAGA TGGCACGATC 
CTAAAAGTCT CAAACAAAGG TCTCAACTCC TATAAAGATC CTGATAATCC TGGGCGAATA 
GCACTTCCTA AACCTCGAAA CCATGGAAAG TTGGATAATA AACAAAGTGT GGATTGGAAT 
AAATTACTCA AGCGGGCATT TGAGGGCTTG GCAGAGTCTG GTGGCTCAAC TTTGAAAAGT 
ATTGAACGCT TTTTGAAAAG CCAGAAGGAT GTGTCTGCTG CCTGTGGAGG CACTGCTGCC 
TCTGGGTTTC ACCAGCAGCT GCGGTTGGCG ATCAAGCGTG CCGTTGGTCA TGGCCGACTC 
CTTAAAGATG GACCTCTCTA CCGGCTCAAC ACCAAGGCAG CCAATGCTGA AGGGAAAGAG 
GGCTGCGAGT CGCTCTCGTG TTTACCTCCT GTGTCACTGC TTCCACACGA GAAAGATAAG 
CCGGTTGCTG AACCAATCCC CATCTGTAGT TTCTGTCTTG GTACAAAAGA ACAAAACCGG 
GAAAAGAAGC CTGAGGACCT CATCTCCTGC GCAGACTGTG GCAATAGCGG TCACCCATCC 
TGCTTAAAGT TCTCCCCAGA ACTCACAGTG AGAGTGAGGG CCCTGCGGTG GCAGTGCATC 
GAGTGCAAAA CGTGCAGCTC CTGTCGCGAT CAAGGCAAAA ACGCAGATAA CATGCTCTTT 
TGTGATTCAT GTGACCGAGG TTTTCACATG GAGTGTTGTG ACCCACCCCT CACACGGATG 
CCAAAAGGCA TGTGGATATG TCAGATATGC CGACCCAGGA AAAAAGGACG GAAACTGCTA 
CAAAAGAAGG CAGCACAGAT AAAACGGCGC TATGCTAATC CAATAGGACG TCCAAAAAAC 
AGGTTAAAGA AACAAAGCAC GGTATCAAAA GGTCCCTTTA GCAAAGTTCG AACTGGTCCT 
GGAAGGGGTC GGAAACGTAA AATCACTGTA TCCAGCCAGT CTGCGTCATC CTCAGAAGAA 
GGCTATTTAG AGCGGATAGA TGGCTTGGAC TTCTGCAGAG ATAGCAGTGC CCCCTTGAAG 
TTCAACAAGA AAACCAAAGG GCTCATTGAT GGCCTTACCA AATTCTTCAC CCCTTCTCCT 
GATGGGCGGA AAGCCCGAGG GGAGGCGGTA GACTACTCTG AGCTCAGAAT CAGGAAAAAG 
GGCAACAGAA AATCAAGTAC TTCACATTGG CCCACAGACA ATCAGGACGG CTGGGAAAGC 
AAACAGGAAA GTGAGGAGCG GCTTTTTGGG AGCCAAGAAA TCATGACGGA AAGAGATATG 
GAATTATTTC GTGATATCCA AGAACAAGCA CTGCAGAAAG TTGGAGTAAC TGGGCCCCCT 
GATCCACAAG TCCGCTGTCC CTCCGTCATT GAGTTTGGGA AGTATGAAAT CCACACCTGG 
TATTCCTCTC CATATCCTCA AGAATACTCA AGGCTGCCTA AATTGTATCT TTGTGAGTTC 
TGTCTAAAAT ATATGAAAAG TAGAACTATT CTCCAGCAGC ACATGAAGAA ATGTGGTTGG 
TTCCATCCTC CCGCCAATGA GATTTACCGA AAGAATAATA TTTCTGTCTT TGAGGTTGAT 
GGGAATGTGA GTACCATTTA TTGTCAAAAT CTGTGTCTCT TGGCAAAGTT GTTTCTTGAC 
CACAAAACAC TCTATTATGA CGTGGAGCCA TTTCTCTTCT ATGTTTTAAC ACAGAATGAT 
GTCAAGGGCT GCCACCTTGT TGGCTACTTT TCTAAAGAAA AGCACTGCCA ACAGAAATAC 
AATGTCTCCT GTATAATGAT TCTTCCCCAA TACCAACGTA AGGGCTACGG CAGGTTTCTC 
ATCGATTTCA GTTATTTGTT ATCAAAGCGT GAAGGCCAAG CAGGCTCTCC TGAGAAACCA 
CTATCAGATC TAGGTCGTCT TTCCTACATG GCTTATTGGA AAAGTGTAAT CTTGGAGTGC 
CTTTATCACC AGAATGACAA ACAGATCAGC ATTAAGAAGC TGAGTAAGCT GACTGGAGTC 
TGCCCGCAAG ACATTACTTC CACACTCCAC CACCTACGGA TGCTGGACTT CCGAAGTGAC 
CAATTTGTGA TTATCCGCCG GGAAAAACTT ATCCAGGATC ACATGGCGAA GCTCCAGCTG 
AATCTTCGAC CTGTCGATGT AGATCCAGAA TGCTTACGCT GGACTCCAGT CATAGTCTCC 
AACTCTGTCG TCTCAGAGGA GGAGGATGAG GAGGCTGATG ACGGAGAGAA AGAAGAGCCC 
CAAGGCCAAG AAAGAGAGTT AGAGACCAGG GAAAGGGTGG GAAAGTCTGT GTCTCGGGAG 
AACAAAGATC AGGATTCTTC CTCTTTAATA GAAAGTGAAA AGAAACCAGA AGTCAAGGAA 
CTAGCCAGCT CTTCACGTCT GAGCAAACAG GCCCTTGTCC GGGACAGTCT TCCTGCAAAT 
AGCCAGCCAC CTCGGAGGGG CCGCTGTGGG AGGAAGAACA GAAAGACACA GGAACGTTTT 
GGTGATAAAG ATTCTAAGAT GCTTGTGGGT GAGACGTTAT CCACTTCTCA GGAGCAATAT 
GGAGAATGCG AGGAGAAGTC AGCAGCCTCC CGAGAGCGTT ACACTGAGGT GGGAGAGCAG 
CCAGCAGCCC CTCAGGCACA AGCAGACGGG AACCCAGACA TCCCCAAGGG CAGGTTCAGT 
GAGAGCGCGG ATTTGTGGCG AGGACAGCTG AAGAAAAGCC CTGAGACCCT GAAGTGCCGA 
TTGCCAGAAG GGAATGACAG ACTTCCGTGC TGCTACACCG ATGGTGACAG GGCTGTCTTT 
AGGGGCTTCA GCGAAAGTAG TGAGGAAGAG GAGGAGCCAG AAAGTCCTCG GTCAAACTCG 
CCACCAGTGC TCACAAAGCC CACGCTGAAA AGAAAGAAAC CAATTCTTCA CCGAAGAAGG 
AGAGTCCGCA AGCGGAAACA CCACAATAGC AGTGTCGTCA CAGAAACGAT CTCTGAGACC 
ACTGAGGTGT TAGATGAGCC TTTTGAAGAC TCTGACTCTG AGAGACCAAT GCCAAGACTG 
GAACCTACAT TCGAGATTGA GGAGGAGGAG GAGGAGGAGG ATGAAAATGA GCTCTTCCCC 
AGAGGGTACT TTCATTGCTT GTCCTCACAG GACATCCTTA GGTGTCAGGC TTCCTCCAAG 
AGGACGGCGT CTAAAGATGA GGAGGAAGAA GAGGAGGAGT CAGACGATGC AGATGACACT 
CCTGTCCTAA AGCCAGTATC TCTCTTGAGA AAATGTGATG TGAACAGTGC TTCACTTGAG 
CCAGATACCT CTACACCTAT GAAAAAGAAA AAGGGATGGC CCAAAGGCAA GAGCCGAAAA 
CCTATCCACT GGAAGAAAAG GCCTGGGCGG AAACCAGGAT TTAAATTGAA TCAGGACATC 
ATAGCTGTTT CTACACAGGA ATGCATAGTT GAGCCCATAG TCCCCATTAA ACCAGGACGT 
AAACCCAGAA CTCAAGAGAG TGAAGAACTT GTTGAGGTGA AGGAGGGCCT GGTGGAAGAA 
AGGAAGGAGG AAATGCATAC AGAAGCAGAC GAAGAGGCCG AGGAGGAAGA GGATGCAGCC 
AGCAGTGACA TTAGAGCCAT GTCCCCATTG GACAGCAGCA ATAGCCCTGA TGCAGACCCG 
AAAGAACCTG AGGCAGAAGA GGAAGAGGAG AAGCCGTTGG ACGATCCGAG GCAATCAGAG 
GAAGAGCCTC AAGAGCTGGA AGAACAGGAG CAAGAGGAAG AGGACGAGGT GACTGCAGAG 
GCAAACCAGA ATGAAGACCA TGATGCTGAC GATGAGGACG ACGGCCACCT GGATTCACTG 
AAGACAAAAG AGCCAGAGGG GCAGCCGGCT AGAGAAGACG GCACAGAGGA GCCCGGCACC 
CAGGAGTCTT TTTTAGATGC AAGCATACAG GACAGCAGGG AGAACGCGAA GGATAAAGAT 
GAAACTGAAG CGGATTCTGA AGAGGAACAG CCTTCCCATG AGGCTTCTGT GGGATCAGAG 
ACCATGCCAG GCTCTGAGGA GGACCATGAG GAGGACTCAA ACACTAAGGA AGAATTAATT 
GAGCTAAAAG AGGAGGAAGA GATCCCACAC AGTGAACTGG ATCTGGAAAC TGTACAGGCA 
GTGCAGTCTT TGACTCAAGA AGAAAGCAGT GAGCATGAAG GAGCCTACCA GGACTGTGAG 
GAAACTCTTG CGGCTTGCCA GACTCTACAG AGTTACACCC ACACTGACGA GGACCCTCAG 
ATGTCAATGG TTGAAGACTG CCATGCCTCA GAGCATAATA GCCCAATATC CTCCATTCCG 
TCTCATCCTA GCCAGTCAGT CCGCTCCGTC AGCAGCCCCA GCATGCCTGC CCTGGAGAGT 
GGCTACACAC AGATCAGCCC AGAGCAAGGA TCCCTGTCCG CACCCTCTAT GCAGAACATG 
GAGACCAGCC CCATGATGGA TGTGCCTTCC GTATCAGACC ACTCTCAGCA GGTGGTAGAC 
AGTGGCTTCA GTGACCTGGG CAGCATCGAG AGCACCACAG AGAACTATGA GAACCCAAGC 
AGCTATGACT CTACCATGGG CAGCAGTATT TGTGGGAATA ACTCCTCTCA GAGCAGCTGC 
TCCTACGGTG GCCTGTCATC TTCAAGCAGC CTCACCCAGA ACAGTTGTGT TGTCACTCAG 
CAAATGGCAA GCATGGGCAA CAGCTGTAGC ATGCTGCAGC AAAACAGCGT CCAACCAGCT 
ACCAACTGCA ACATCAAGTC GCCTCAGACC TGTGTGGTGG AAAGGCCTCC CAGTAACCAG 
CAGCCGCCGC CACCACCACC ACCCCCGCCG CCACCACAGC AGCCGCAGCC GCAGCCGCAG 
CAGCAGGCAG CCCCACAGCC TCCCCCACCA CAGCCGCAGC AGCAGCCGCC CCCTCCACCG 
CAGCAGCAGC CCCAGCCCCC ACCTCCACCC CAGCAGCAGC CCCCTCTGTC GCAGTGTAGC 
ATGAACAACA GCTTCACTGC CGCGCCAATG ATAATGGAGA TACCAGAGTC CGGGGGTACT 
GGGAACATCA GCATCTACGA GAGGATTCCA GGGGATTTTG GCGCTGGCAG CTACTCTCAA 
CCGTCAGCCA CCTTCAGTCT CGCCAAGTTG CAGCAGCTGA CTAACACCAT TATGGACCCT 
CATGCCATGC CTTACAGTCA TTCTCCGGCC GTGACTTCCT ATGCAACCAG TGTTTCTCTG 
TCTAATACGG GACTGGCTCA GCTAGCTCCA TCTCATCCCT TAGCCGGGAC CCCTCAAGCA 
CAAGCCACCA TGACGCCACC CCCAAACTTG GCACCTACTA CTATGAACCT CACGTCACCT 
CTGCTGCAGT GCAACATGTC TGCCACCAAC ATTGGGATCC CTCACACGCA GAGGTTGCAG 
GGGCAGATGC CAGTCAAGGG GCACATTTCT ATCCGTTCCA AGTCTGCACC TTTACCCTCT 
GCAACTGCAC ACCAACAGCA GCTCTATGGC CGCAGCCCCC CAGCAGTTGC CATGCAGGCT 
GGCCCTCGTG CACTGGCCGT TCAGCGTGGC ATGAACATGG GGGTTAACTT AATGCCCACT 
CCAGCCTATA ATGTCAATTC CATGAATATG AACACCTTGA ATGCCATGAA CAGCTATCGA 
ATGACACAGC CCATGATGAA CAGCAGTTAC CATAGTAACC CTGCCTACAT GAACCAGACA 
GCACAGTATC CTATGCAGAT GCAGATGGGA ATGATGGGGA GCCAGGCCTA TACCCAGCAG 
CCTATGCAGC CAAACCCTCA TGGAAACATG ATGTACACTG GCCCCTCCCA TCACAGCTAC 
ATGAATGCTG CCGGCGTCCC CAAGCAGTCA CTTAATGGAC CTTACATGAG AAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001094040.1
CDS	314..6310
Translation	MVKLANPLYTQWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTILKVSNKGLNSYKDPDNPGRIALPKPRNHGKLDNKQSVDWNKLLKRAFEGLAESGGSTLKSIERFLKSQKDVSAACGGTAASGFHQQLRLAIKRAVGHGRLLKDGPLYRLNTKAANAEGKEGCESLSCLPPVSLLPHEKDKPVAEPIPICSFCLGTKEQNREKKPEDLISCADCGNSGHPSCLKFSPELTVRVRALRWQCIECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRMPKGMWICQICRPRKKGRKLLQKKAAQIKRRYANPIGRPKNRLKKQSTVSKGPFSKVRTGPGRGRKRKITVSSQSASSSEEGYLERIDGLDFCRDSSAPLKFNKKTKGLIDGLTKFFTPSPDGRKARGEAVDYSELRIRKKGNRKSSTSHWPTDNQDGWESKQESEERLFGSQEIMTERDMELFRDIQEQALQKVGVTGPPDPQVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQHMKKCGWFHPPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVKGCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQAGSPEKPLSDLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLTGVCPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVIVSNSVVSEEEDEEADDGEKEEPQGQERELETRERVGKSVSRENKDQDSSSLIESEKKPEVKELASSSRLSKQALVRDSLPANSQPPRRGRCGRKNRKTQERFGDKDSKMLVGETLSTSQEQYGECEEKSAASRERYTEVGEQPAAPQAQADGNPDIPKGRFSESADLWRGQLKKSPETLKCRLPEGNDRLPCCYTDGDRAVFRGFSESSEEEEEPESPRSNSPPVLTKPTLKRKKPILHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIEEEEEEEDENELFPRGYFHCLSSQDILRCQASSKRTASKDEEEEEEESDDADDTPVLKPVSLLRKCDVNSASLEPDTSTPMKKKKGWPKGKSRKPIHWKKRPGRKPGFKLNQDIIAVSTQECIVEPIVPIKPGRKPRTQESEELVEVKEGLVEERKEEMHTEADEEAEEEEDAASSDIRAMSPLDSSNSPDADPKEPEAEEEEEKPLDDPRQSEEEPQELEEQEQEEEDEVTAEANQNEDHDADDEDDGHLDSLKTKEPEGQPAREDGTEEPGTQESFLDASIQDSRENAKDKDETEADSEEEQPSHEASVGSETMPGSEEDHEEDSNTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTHTDEDPQMSMVEDCHASEHNSPISSIPSHPSQSVRSVSSPSMPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGSSICGNNSSQSSCSYGGLSSSSSLTQNSCVVTQQMASMGNSCSMLQQNSVQPATNCNIKSPQTCVVERPPSNQQPPPPPPPPPPPQQPQPQPQQQAAPQPPPPQPQQQPPPPPQQQPQPPPPPQQQPPLSQCSMNNSFTAAPMIMEIPESGGTGNISIYERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPPNLAPTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSKSAPLPSATAHQQQLYGRSPPAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLNAMNSYRMTQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQPMQPNPHGNMMYTGPSHHSYMNAAGVPKQSLNGPYMRR

Target ORF information:

RefSeq Version	NM_001100570.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lysine acetyltransferase 6A (Kat6a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100570.2

ORF Insert Sequence:

ATGGTAAAGC TCGCTAACCC GCTGTACACG CAGTGGATTT TGGAGGCCAT CAAAAAAGTC 
AAGAAGCAGA AACAGCGACC TTCAGAAGAA AGAATATGCA ATGCAGTGTC GTCCTCCCAC 
GGCTTAGATC GGAAAACTGT CCTGGAGCAG TTGGAGCTGA GTGTTAAAGA TGGCACGATC 
CTAAAAGTCT CAAACAAAGG TCTCAACTCC TATAAAGATC CTGATAATCC TGGGCGAATA 
GCACTTCCTA AACCTCGAAA CCATGGAAAG TTGGATAATA AACAAAGTGT GGATTGGAAT 
AAATTACTCA AGCGGGCATT TGAGGGCTTG GCAGAGTCTG GTGGCTCAAC TTTGAAAAGT 
ATTGAACGCT TTTTGAAAAG CCAGAAGGAT GTGTCTGCTG CCTGTGGAGG CACTGCTGCC 
TCTGGGTTTC ACCAGCAGCT GCGGTTGGCG ATCAAGCGTG CCGTTGGTCA TGGCCGACTC 
CTTAAAGATG GACCTCTCTA CCGGCTCAAC ACCAAGGCAG CCAATGCTGA AGGGAAAGAG 
GGCTGCGAGT CGCTCTCGTG TTTACCTCCT GTGTCACTGC TTCCACACGA GAAAGATAAG 
CCGGTTGCTG AACCAATCCC CATCTGTAGT TTCTGTCTTG GTACAAAAGA ACAAAACCGG 
GAAAAGAAGC CTGAGGACCT CATCTCCTGC GCAGACTGTG GCAATAGCGG TCACCCATCC 
TGCTTAAAGT TCTCCCCAGA ACTCACAGTG AGAGTGAGGG CCCTGCGGTG GCAGTGCATC 
GAGTGCAAAA CGTGCAGCTC CTGTCGCGAT CAAGGCAAAA ACGCAGATAA CATGCTCTTT 
TGTGATTCAT GTGACCGAGG TTTTCACATG GAGTGTTGTG ACCCACCCCT CACACGGATG 
CCAAAAGGCA TGTGGATATG TCAGATATGC CGACCCAGGA AAAAAGGACG GAAACTGCTA 
CAAAAGAAGG CAGCACAGAT AAAACGGCGC TATGCTAATC CAATAGGACG TCCAAAAAAC 
AGGTTAAAGA AACAAAGCAC GGTATCAAAA GGTCCCTTTA GCAAAGTTCG AACTGGTCCT 
GGAAGGGGTC GGAAACGTAA AATCACTGTA TCCAGCCAGT CTGCGTCATC CTCAGAAGAA 
GGCTATTTAG AGCGGATAGA TGGCTTGGAC TTCTGCAGAG ATAGCAGTGC CCCCTTGAAG 
TTCAACAAGA AAACCAAAGG GCTCATTGAT GGCCTTACCA AATTCTTCAC CCCTTCTCCT 
GATGGGCGGA AAGCCCGAGG GGAGGCGGTA GACTACTCTG AGCTCAGAAT CAGGAAAAAG 
GGCAACAGAA AATCAAGTAC TTCACATTGG CCCACAGACA ATCAGGACGG CTGGGAAAGC 
AAACAGGAAA GTGAGGAGCG GCTTTTTGGG AGCCAAGAAA TCATGACGGA AAGAGATATG 
GAATTATTTC GTGATATCCA AGAACAAGCA CTGCAGAAAG TTGGAGTAAC TGGGCCCCCT 
GATCCACAAG TCCGCTGTCC CTCCGTCATT GAGTTTGGGA AGTATGAAAT CCACACCTGG 
TATTCCTCTC CATATCCTCA AGAATACTCA AGGCTGCCTA AATTGTATCT TTGTGAGTTC 
TGTCTAAAAT ATATGAAAAG TAGAACTATT CTCCAGCAGC ACATGAAGAA ATGTGGTTGG 
TTCCATCCTC CCGCCAATGA GATTTACCGA AAGAATAATA TTTCTGTCTT TGAGGTTGAT 
GGGAATGTGA GTACCATTTA TTGTCAAAAT CTGTGTCTCT TGGCAAAGTT GTTTCTTGAC 
CACAAAACAC TCTATTATGA CGTGGAGCCA TTTCTCTTCT ATGTTTTAAC ACAGAATGAT 
GTCAAGGGCT GCCACCTTGT TGGCTACTTT TCTAAAGAAA AGCACTGCCA ACAGAAATAC 
AATGTCTCCT GTATAATGAT TCTTCCCCAA TACCAACGTA AGGGCTACGG CAGGTTTCTC 
ATCGATTTCA GTTATTTGTT ATCAAAGCGT GAAGGCCAAG CAGGCTCTCC TGAGAAACCA 
CTATCAGATC TAGGTCGTCT TTCCTACATG GCTTATTGGA AAAGTGTAAT CTTGGAGTGC 
CTTTATCACC AGAATGACAA ACAGATCAGC ATTAAGAAGC TGAGTAAGCT GACTGGAGTC 
TGCCCGCAAG ACATTACTTC CACACTCCAC CACCTACGGA TGCTGGACTT CCGAAGTGAC 
CAATTTGTGA TTATCCGCCG GGAAAAACTT ATCCAGGATC ACATGGCGAA GCTCCAGCTG 
AATCTTCGAC CTGTCGATGT AGATCCAGAA TGCTTACGCT GGACTCCAGT CATAGTCTCC 
AACTCTGTCG TCTCAGAGGA GGAGGATGAG GAGGCTGATG ACGGAGAGAA AGAAGAGCCC 
CAAGGCCAAG AAAGAGAGTT AGAGACCAGG GAAAGGGTGG GAAAGTCTGT GTCTCGGGAG 
AACAAAGATC AGGATTCTTC CTCTTTAATA GAAAGTGAAA AGAAACCAGA AGTCAAGGAA 
CTAGCCAGCT CTTCACGTCT GAGCAAACAG GCCCTTGTCC GGGACAGTCT TCCTGCAAAT 
AGCCAGCCAC CTCGGAGGGG CCGCTGTGGG AGGAAGAACA GAAAGACACA GGAACGTTTT 
GGTGATAAAG ATTCTAAGAT GCTTGTGGGT GAGACGTTAT CCACTTCTCA GGAGCAATAT 
GGAGAATGCG AGGAGAAGTC AGCAGCCTCC CGAGAGCGTT ACACTGAGGT GGGAGAGCAG 
CCAGCAGCCC CTCAGGCACA AGCAGACGGG AACCCAGACA TCCCCAAGGG CAGGTTCAGT 
GAGAGCGCGG ATTTGTGGCG AGGACAGCTG AAGAAAAGCC CTGAGACCCT GAAGTGCCGA 
TTGCCAGAAG GGAATGACAG ACTTCCGTGC TGCTACACCG ATGGTGACAG GGCTGTCTTT 
AGGGGCTTCA GCGAAAGTAG TGAGGAAGAG GAGGAGCCAG AAAGTCCTCG GTCAAACTCG 
CCACCAGTGC TCACAAAGCC CACGCTGAAA AGAAAGAAAC CAATTCTTCA CCGAAGAAGG 
AGAGTCCGCA AGCGGAAACA CCACAATAGC AGTGTCGTCA CAGAAACGAT CTCTGAGACC 
ACTGAGGTGT TAGATGAGCC TTTTGAAGAC TCTGACTCTG AGAGACCAAT GCCAAGACTG 
GAACCTACAT TCGAGATTGA GGAGGAGGAG GAGGAGGAGG ATGAAAATGA GCTCTTCCCC 
AGAGGGTACT TTCATTGCTT GTCCTCACAG GACATCCTTA GGTGTCAGGC TTCCTCCAAG 
AGGACGGCGT CTAAAGATGA GGAGGAAGAA GAGGAGGAGT CAGACGATGC AGATGACACT 
CCTGTCCTAA AGCCAGTATC TCTCTTGAGA AAATGTGATG TGAACAGTGC TTCACTTGAG 
CCAGATACCT CTACACCTAT GAAAAAGAAA AAGGGATGGC CCAAAGGCAA GAGCCGAAAA 
CCTATCCACT GGAAGAAAAG GCCTGGGCGG AAACCAGGAT TTAAATTGAA TCAGGACATC 
ATAGCTGTTT CTACACAGGA ATGCATAGTT GAGCCCATAG TCCCCATTAA ACCAGGACGT 
AAACCCAGAA CTCAAGAGAG TGAAGAACTT GTTGAGGTGA AGGAGGGCCT GGTGGAAGAA 
AGGAAGGAGG AAATGCATAC AGAAGCAGAC GAAGAGGCCG AGGAGGAAGA GGATGCAGCC 
AGCAGTGACA TTAGAGCCAT GTCCCCATTG GACAGCAGCA ATAGCCCTGA TGCAGACCCG 
AAAGAACCTG AGGCAGAAGA GGAAGAGGAG AAGCCGTTGG ACGATCCGAG GCAATCAGAG 
GAAGAGCCTC AAGAGCTGGA AGAACAGGAG CAAGAGGAAG AGGACGAGGT GACTGCAGAG 
GCAAACCAGA ATGAAGACCA TGATGCTGAC GATGAGGACG ACGGCCACCT GGATTCACTG 
AAGACAAAAG AGCCAGAGGG GCAGCCGGCT AGAGAAGACG GCACAGAGGA GCCCGGCACC 
CAGGAGTCTT TTTTAGATGC AAGCATACAG GACAGCAGGG AGAACGCGAA GGATAAAGAT 
GAAACTGAAG CGGATTCTGA AGAGGAACAG CCTTCCCATG AGGCTTCTGT GGGATCAGAG 
ACCATGCCAG GCTCTGAGGA GGACCATGAG GAGGACTCAA ACACTAAGGA AGAATTAATT 
GAGCTAAAAG AGGAGGAAGA GATCCCACAC AGTGAACTGG ATCTGGAAAC TGTACAGGCA 
GTGCAGTCTT TGACTCAAGA AGAAAGCAGT GAGCATGAAG GAGCCTACCA GGACTGTGAG 
GAAACTCTTG CGGCTTGCCA GACTCTACAG AGTTACACCC ACACTGACGA GGACCCTCAG 
ATGTCAATGG TTGAAGACTG CCATGCCTCA GAGCATAATA GCCCAATATC CTCCATTCCG 
TCTCATCCTA GCCAGTCAGT CCGCTCCGTC AGCAGCCCCA GCATGCCTGC CCTGGAGAGT 
GGCTACACAC AGATCAGCCC AGAGCAAGGA TCCCTGTCCG CACCCTCTAT GCAGAACATG 
GAGACCAGCC CCATGATGGA TGTGCCTTCC GTATCAGACC ACTCTCAGCA GGTGGTAGAC 
AGTGGCTTCA GTGACCTGGG CAGCATCGAG AGCACCACAG AGAACTATGA GAACCCAAGC 
AGCTATGACT CTACCATGGG CAGCAGTATT TGTGGGAATA ACTCCTCTCA GAGCAGCTGC 
TCCTACGGTG GCCTGTCATC TTCAAGCAGC CTCACCCAGA ACAGTTGTGT TGTCACTCAG 
CAAATGGCAA GCATGGGCAA CAGCTGTAGC ATGCTGCAGC AAAACAGCGT CCAACCAGCT 
ACCAACTGCA ACATCAAGTC GCCTCAGACC TGTGTGGTGG AAAGGCCTCC CAGTAACCAG 
CAGCCGCCGC CACCACCACC ACCCCCGCCG CCACCACAGC AGCCGCAGCC GCAGCCGCAG 
CAGCAGGCAG CCCCACAGCC TCCCCCACCA CAGCCGCAGC AGCAGCCGCC CCCTCCACCG 
CAGCAGCAGC CCCAGCCCCC ACCTCCACCC CAGCAGCAGC CCCCTCTGTC GCAGTGTAGC 
ATGAACAACA GCTTCACTGC CGCGCCAATG ATAATGGAGA TACCAGAGTC CGGGGGTACT 
GGGAACATCA GCATCTACGA GAGGATTCCA GGGGATTTTG GCGCTGGCAG CTACTCTCAA 
CCGTCAGCCA CCTTCAGTCT CGCCAAGTTG CAGCAGCTGA CTAACACCAT TATGGACCCT 
CATGCCATGC CTTACAGTCA TTCTCCGGCC GTGACTTCCT ATGCAACCAG TGTTTCTCTG 
TCTAATACGG GACTGGCTCA GCTAGCTCCA TCTCATCCCT TAGCCGGGAC CCCTCAAGCA 
CAAGCCACCA TGACGCCACC CCCAAACTTG GCACCTACTA CTATGAACCT CACGTCACCT 
CTGCTGCAGT GCAACATGTC TGCCACCAAC ATTGGGATCC CTCACACGCA GAGGTTGCAG 
GGGCAGATGC CAGTCAAGGG GCACATTTCT ATCCGTTCCA AGTCTGCACC TTTACCCTCT 
GCAACTGCAC ACCAACAGCA GCTCTATGGC CGCAGCCCCC CAGCAGTTGC CATGCAGGCT 
GGCCCTCGTG CACTGGCCGT TCAGCGTGGC ATGAACATGG GGGTTAACTT AATGCCCACT 
CCAGCCTATA ATGTCAATTC CATGAATATG AACACCTTGA ATGCCATGAA CAGCTATCGA 
ATGACACAGC CCATGATGAA CAGCAGTTAC CATAGTAACC CTGCCTACAT GAACCAGACA 
GCACAGTATC CTATGCAGAT GCAGATGGGA ATGATGGGGA GCCAGGCCTA TACCCAGCAG 
CCTATGCAGC CAAACCCTCA TGGAAACATG ATGTACACTG GCCCCTCCCA TCACAGCTAC 
ATGAATGCTG CCGGCGTCCC CAAGCAGTCA CTTAATGGAC CTTACATGAG AAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

KAT6A, a chromatin modifier from the 8p11-p12 amplicon is a candidate oncogene in luminal breast cancer.
Neoplasia (New York, N.Y.)16(8)644-55(2014 Aug)
Turner-Ivey B,Guest ST,Irish JC,Kappler CS,Garrett-Mayer E,Wilson RC,Ethier SP

The leucine twenty homeobox (LEUTX) gene, which lacks a histone acetyltransferase domain, is fused to KAT6A in therapy-related acute myeloid leukemia with t(8;19)(p11;q13).
Genes, chromosomes & cancer53(4)299-308(2014 Apr)
Chinen Y,Taki T,Tsutsumi Y,Kobayashi S,Matsumoto Y,Sakamoto N,Kuroda J,Horiike S,Nishida K,Ohno H,Uike N,Taniwaki M

MOZ increases p53 acetylation and premature senescence through its complex formation with PML.
Proceedings of the National Academy of Sciences of the United States of America110(10)3895-900(2013 Mar)
Rokudai S,Laptenko O,Arnal SM,Taya Y,Kitabayashi I,Prives C

MOZ regulates the Tbx1 locus, and Moz mutation partially phenocopies DiGeorge syndrome.
Developmental cell23(3)652-63(2012 Sep)
Voss AK,Vanyai HK,Collin C,Dixon MP,McLennan TJ,Sheikh BN,Scambler P,Thomas T

Physical and functional HAT/HDAC interplay regulates protein acetylation balance.
Journal of biomedicine & biotechnology2011371832(2011)
Peserico A,Simone C

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Kat6a cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

ORF Insert Sequence:

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