Nfkbiz cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Nfkbiz
Entrez Gene ID	304005
Full Name	NFKB inhibitor zeta
Synonyms	Mail,RGD1310834
General protein information	Preferred Names NFKB inhibitor zeta Names NF-kappa-B inhibitor zeta IkappaB-zeta molecule possessing ankyrin-repeats induced by lipopolysaccharide nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 11 Map Location: 11q12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001107095.1	NP_001100565.1	NF-kappa-B inhibitor zeta

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	NFKBIZ	XP_005639490.1
Gallus gallus (chicken)	NFKBIZ	NP_001006254.1
Xenopus tropicalis (tropical clawed frog)	LOC100485153	XP_002932322.1
Pan troglodytes (chimpanzee)	NFKBIZ	XP_516633.3
Mus musculus (house mouse)	Nfkbiz	NP_001152866.1
Bos taurus (cattle)	NFKBIZ	NP_777151.1
Rattus norvegicus (Norway rat)	Nfkbiz	NP_001100565.1
Xenopus tropicalis (tropical clawed frog)	nfkbiz	NP_001123738.1
Homo sapiens (human)	NFKBIZ	NP_113607.1
Macaca mulatta (Rhesus monkey)	NFKBIZ	XP_001099425.1

Gene Ontology
Bibliography

Related articles in PubMed

Involvement of NF-κBIZ and related cytokines in age-associated renal fibrosis.
Chung KW, Jeong HO, Lee B, Park D, Kim DH, Choi YJ, Lee EK, Kim KM, Park JW, Yu BP, Chung HY
Oncotarget8(5)7315-7327(2017 Jan)

Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote T(H)17 differentiation.
Jeltsch KM, Hu D, Brenner S, Zöller J, Heinz GA, Nagel D, Vogel KU, Rehage N, Warth SC, Edelmann SL, Gloury R, Martin N, Lohs C, Lech M, Stehklein JE, Geerlof A, Kremmer E, Weber A, Anders HJ, Schmitz I, Schmidt-Supprian M, Fu M, Holtmann H, Krappmann D, Ruland J, Kallies A, Heikenwalder M, Heissmeyer V
Nature immunology15(11)1079-89(2014 Nov)

IL-10-induced microRNA-187 negatively regulates TNF-α, IL-6, and IL-12p40 production in TLR4-stimulated monocytes.
Rossato M, Curtale G, Tamassia N, Castellucci M, Mori L, Gasperini S, Mariotti B, De Luca M, Mirolo M, Cassatella MA, Locati M, Bazzoni F
Proceedings of the National Academy of Sciences of the United States of America109(45)E3101-10(2012 Nov)

MAIL, a novel nuclear I kappa B protein that potentiates LPS-induced IL-6 production.
Kitamura H, Kanehira K, Okita K, Morimatsu M, Saito M
FEBS letters485(1)53-6(2000 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Nfkbiz gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nfkbiz cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02872	NM_001107095.1 Latest version!	Rattus norvegicus NFKB inhibitor zeta (Nfkbiz), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nfkbiz ( NM_001107095.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100565.1 Rattus norvegicus NFKB inhibitor zeta (Nfkbiz), mRNA.

Price & Availability↑

CloneID	ORa02872
Clone ID Related Accession (Same CDS sequence)	NM_001107095.1
Accession Version	NM_001107095.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1140bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1555516800000
Organism	Rattus norvegicus(Norway rat)
Product	NF-kappa-B inhibitor zeta
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473967.1. On or before Oct 4, 2007 this sequence version replaced XM_221537.4, XM_001062534.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGATCGTGG ACAAGCTGCT GGACGACAGC CGCGGCGGAG AGGGGCTGCT GGACGCGGCC 
GGCGACTGCG GCCTCATGAC CAGCCCGCTC AACCTCGCTT ACTTCTACGG AGCCTCGCCT 
CCCTCCGCCC CCGGCGCCGG CGACACCGGT TACCTGTCCG CGGTTCCCTC CGCGCCCGGC 
TCGCCCGGCT CCGACTCTTC CGATTTCTCC TCCACTTCCT CCGTGTCCTC CTGCGGGGCC 
GTGGAGTCCC GTCCGAGAGG TGGCGCCCGC GCCGAGCGCC CGCAAGTTGA GCCCCATATG 
GGGGTGGGCA GGCAGCAGAG AGGCCCCTTT CAAGGTGTTC GAGTGAAGAA CTCGGTGAAA 
GAGCTGCTGC TGCACATCCG AAGTAATAAA CAGAAGACTT CCGGCCAAGC GGTGGACGAG 
TTTAAGAGTG CCTTTCAGGT GGCTGTCGCT GCCAATCAGC ACCTCATTGT GCAAGACCTG 
GTGAACCTTG GTGCCCAGGT GAACACCACA GACTGCTGGG GAAGGACACC TCTGCATGTC 
TGTGCAGAGA AGGGCCACTC CCAGGTGCTC CAGGCAATCC AGAAGGGAGC AGTGAGGAGC 
AATCAGTTTG TGGATCTGGA GGCAACGAAC TATGATGGCC TGACTCCCCT CCACTGTGCG 
GTCCTGGCTC ACAATTCGGT GGTGCACGAC CTGCAGAGAA GCCAGCAGCC TCATTCGCCC 
GAGGTGCAGG ATCTCTTACT GAAGAATAAG AGCTTGGTTG ACACCATTAA GTGTCTGATT 
CAGATGGGAG CGGCCGTGGA GGCGAAGGAT CGTAAAAGTG GCCGCACGGC CCTGCATTTG 
GCAGCGGAGG AAGCAAATCT GGAACTCATT CGCCTCTTTT TGGAGTTGCC GAGTTGCCTG 
TCTTTCGTGA ATGCAAAGGC TTACAATGGA AACACCGCCC TCCATGTTGC TGCCAGCCTG 
CAGTATCGGG TGACACAGTT GGATGCAGTC CGTCTGTTGA TGAGGAAGGG AGCCGACCCC 
AGTACTCGGA ACTTGGAGAA TGAACAGCCG GTGCATTTGG TCCCTGATGG CCCTGTGGGA 
GAACAGATCC GACGTATCCT GAAGGGGAAG TCCATTCAGC AGCGAGTACC ACCATACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100565.1
CDS	530..1669
Translation	MIVDKLLDDSRGGEGLLDAAGDCGLMTSPLNLAYFYGASPPSAPGAGDTGYLSAVPSAPGSPGSDSSDFSSTSSVSSCGAVESRPRGGARAERPQVEPHMGVGRQQRGPFQGVRVKNSVKELLLHIRSNKQKTSGQAVDEFKSAFQVAVAANQHLIVQDLVNLGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVRSNQFVDLEATNYDGLTPLHCAVLAHNSVVHDLQRSQQPHSPEVQDLLLKNKSLVDTIKCLIQMGAAVEAKDRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRVTQLDAVRLLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRVPPY

Target ORF information:

RefSeq Version	NM_001107095.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus NFKB inhibitor zeta (Nfkbiz), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107095.1

ORF Insert Sequence:

ATGATCGTGG ACAAGCTGCT GGACGACAGC CGCGGCGGAG AGGGGCTGCT GGACGCGGCC 
GGCGACTGCG GCCTCATGAC CAGCCCGCTC AACCTCGCTT ACTTCTACGG AGCCTCGCCT 
CCCTCCGCCC CCGGCGCCGG CGACACCGGT TACCTGTCCG CGGTTCCCTC CGCGCCCGGC 
TCGCCCGGCT CCGACTCTTC CGATTTCTCC TCCACTTCCT CCGTGTCCTC CTGCGGGGCC 
GTGGAGTCCC GTCCGAGAGG TGGCGCCCGC GCCGAGCGCC CGCAAGTTGA GCCCCATATG 
GGGGTGGGCA GGCAGCAGAG AGGCCCCTTT CAAGGTGTTC GAGTGAAGAA CTCGGTGAAA 
GAGCTGCTGC TGCACATCCG AAGTAATAAA CAGAAGACTT CCGGCCAAGC GGTGGACGAG 
TTTAAGAGTG CCTTTCAGGT GGCTGTCGCT GCCAATCAGC ACCTCATTGT GCAAGACCTG 
GTGAACCTTG GTGCCCAGGT GAACACCACA GACTGCTGGG GAAGGACACC TCTGCATGTC 
TGTGCAGAGA AGGGCCACTC CCAGGTGCTC CAGGCAATCC AGAAGGGAGC AGTGAGGAGC 
AATCAGTTTG TGGATCTGGA GGCAACGAAC TATGATGGCC TGACTCCCCT CCACTGTGCG 
GTCCTGGCTC ACAATTCGGT GGTGCACGAC CTGCAGAGAA GCCAGCAGCC TCATTCGCCC 
GAGGTGCAGG ATCTCTTACT GAAGAATAAG AGCTTGGTTG ACACCATTAA GTGTCTGATT 
CAGATGGGAG CGGCCGTGGA GGCGAAGGAT CGTAAAAGTG GCCGCACGGC CCTGCATTTG 
GCAGCGGAGG AAGCAAATCT GGAACTCATT CGCCTCTTTT TGGAGTTGCC GAGTTGCCTG 
TCTTTCGTGA ATGCAAAGGC TTACAATGGA AACACCGCCC TCCATGTTGC TGCCAGCCTG 
CAGTATCGGG TGACACAGTT GGATGCAGTC CGTCTGTTGA TGAGGAAGGG AGCCGACCCC 
AGTACTCGGA ACTTGGAGAA TGAACAGCCG GTGCATTTGG TCCCTGATGG CCCTGTGGGA 
GAACAGATCC GACGTATCCT GAAGGGGAAG TCCATTCAGC AGCGAGTACC ACCATACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Involvement of NF-κBIZ and related cytokines in age-associated renal fibrosis.
Oncotarget8(5)7315-7327(2017 Jan)
Chung KW,Jeong HO,Lee B,Park D,Kim DH,Choi YJ,Lee EK,Kim KM,Park JW,Yu BP,Chung HY

Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote T(H)17 differentiation.
Nature immunology15(11)1079-89(2014 Nov)
Jeltsch KM,Hu D,Brenner S,Zöller J,Heinz GA,Nagel D,Vogel KU,Rehage N,Warth SC,Edelmann SL,Gloury R,Martin N,Lohs C,Lech M,Stehklein JE,Geerlof A,Kremmer E,Weber A,Anders HJ,Schmitz I,Schmidt-Supprian M,Fu M,Holtmann H,Krappmann D,Ruland J,Kallies A,Heikenwalder M,Heissmeyer V

IL-10-induced microRNA-187 negatively regulates TNF-α, IL-6, and IL-12p40 production in TLR4-stimulated monocytes.
Proceedings of the National Academy of Sciences of the United States of America109(45)E3101-10(2012 Nov)
Rossato M,Curtale G,Tamassia N,Castellucci M,Mori L,Gasperini S,Mariotti B,De Luca M,Mirolo M,Cassatella MA,Locati M,Bazzoni F

MAIL, a novel nuclear I kappa B protein that potentiates LPS-induced IL-6 production.
FEBS letters485(1)53-6(2000 Nov)
Kitamura H,Kanehira K,Okita K,Morimatsu M,Saito M

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Nfkbiz cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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