| Gene Symbol | Gpr143 |
| Entrez Gene ID | 302619 |
| Full Name | G protein-coupled receptor 143 |
| Synonyms | RGD1565799 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
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Gpr143 cDNA ORF clone, Rattus norvegicus(Norway rat)
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Gene
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Clones
gRNAs
The following Gpr143 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gpr143 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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Reference Sequences (Refseq)
CloneID ORa02606 Clone ID Related Accession (Same CDS sequence) NM_001106958.1 Accession Version NM_001106958.1 Latest version! Documents for ORF clone product in default vector Sequence Information ORF Nucleotide Sequence (Length: 1218bp)
Protein sequence
SNPVector pcDNA3.1-C-(k)DYK or customized vector 
User ManualClone information Clone Map MSDSTag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags ORF Insert Method CloneEZ™ Seamless cloning technology Insert Structure linear Update Date 1527350400000 Organism Rattus norvegicus(Norway rat) Product G-protein coupled receptor 143 Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474014.2. On or before Oct 4, 2007 this sequence version replaced XM_001064908.1, XM_228848.4. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296 [ECO:0000348] ##Evidence-Data-END##
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201ATGGCCTCCC CGCGCCTGGG AATCTTCTGC TGCCCTTCGT GGGATGCAGC CACACAGCTG
GTGCTGACCT TCCAACCGCG GGTGTTCCAT GCGCTGTGTC TGGGCAGCGG CGCCCTCCGC
CTGGTGCTTG GCCTCCTTCA GCTCCTAACA GGGCGCCGAT CTGTTGGTCA CAGGGCGCCT
GCGACAACCC CAGCAGCCTC AGTCCACATC CTTCGTGCTG CCACCGCCTG TGATTTGCTT
GGCTGCCTGG GAATCGTTAT CAGGTCCACA GTGTGGATAG CCTACCCAGA ATTCATTGAA
AACATTTCCA ATATGAATGG AACAGACATT TGGCCTACTG CTTTCTGTGT CGGGAGTGCA
ATGTGGATCC AGCTGTTGTA CAGTGCCTGC TTCTGGTGGC TCTTCTGCTA TGCAGTTGAT
GTATACTTGG TGATCAGGAG ATCAGCAGGA CGGAGCACCA TCCTGCTGTA CCACATCATG
GCCTGGGGCC TGCCTGTGCT GCTCTGTGTG GAAGGTGCAG TCATGCTTTA TTACCCTTCT
GTGTCCAGGT GTGAGAGAGG CCTGGACCAT GCCATCCCCC ATTATGTCAC CACATACTTG
CCACTTATGC TTGTCCTTGT GGCCAACCCG ATCCTGTTTC ACAAGACAGT GATTTCAGTG
GCCTCTTTAC TGAAAGGACG AAAAGGTGTT TATACAGAGA ATGAGAGATT GATGGGGGCC
GTGATCAAGA CCCGGTTTTT CAAAATAATG CTGGTGTTAA TTGCATGTTG GTTGTCCAAT
ATCATCAATG AATGTCTTTT GTTCTACCTT GAAATGCAAC CAGATACCCA TGGAGGCTCT
CTGAAACGCA TCCAGAATGC AGCCAGGACC ACATGGTTTA TTATGGGAAT ATTGAATCCA
TCTCAAGGAC TTCTCTTGTC TCTGGCCTTC TATGGCTGGA CAGGATGCAG CCTGGATGTC
CATGCTCCCA AGATGGTGAT TCAGTGGGAA ACAATGACTG CCTCGGCTGC TGAGGGCACA
TATCAGACCC CTGAGGGTTC CTGTGTGCCC CATCAAAACC CCAGGAAGGT GGTGTGTGTT
GGGGGGCACA CTTCTGATGA GGTGCTGAGT ATTTTGTCTG AAGGTTCGGA TGCTAGCACT
GTTGAAATCC ATACTGCAAC TGGGTCCCAC AACATAAAGG AAGTTGACTC CATTTCCCAA
GCCCAGGGGG ATCTCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq NP_001100428.1 CDS 67..1284 Translation 
Target ORF information:
RefSeq Version NM_001106958.1 Organism Rattus norvegicus(Norway rat) Definition Rattus norvegicus G protein-coupled receptor 143 (Gpr143), mRNA. Target ORF information:
Epitope DYKDDDDK Bacterial selection AMPR Mammalian selection NeoR Vector pcDNA3.1+/C-(K)DYK 
NM_001106958.1
ORF Insert Sequence:
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201ATGGCCTCCC CGCGCCTGGG AATCTTCTGC TGCCCTTCGT GGGATGCAGC CACACAGCTG
GTGCTGACCT TCCAACCGCG GGTGTTCCAT GCGCTGTGTC TGGGCAGCGG CGCCCTCCGC
CTGGTGCTTG GCCTCCTTCA GCTCCTAACA GGGCGCCGAT CTGTTGGTCA CAGGGCGCCT
GCGACAACCC CAGCAGCCTC AGTCCACATC CTTCGTGCTG CCACCGCCTG TGATTTGCTT
GGCTGCCTGG GAATCGTTAT CAGGTCCACA GTGTGGATAG CCTACCCAGA ATTCATTGAA
AACATTTCCA ATATGAATGG AACAGACATT TGGCCTACTG CTTTCTGTGT CGGGAGTGCA
ATGTGGATCC AGCTGTTGTA CAGTGCCTGC TTCTGGTGGC TCTTCTGCTA TGCAGTTGAT
GTATACTTGG TGATCAGGAG ATCAGCAGGA CGGAGCACCA TCCTGCTGTA CCACATCATG
GCCTGGGGCC TGCCTGTGCT GCTCTGTGTG GAAGGTGCAG TCATGCTTTA TTACCCTTCT
GTGTCCAGGT GTGAGAGAGG CCTGGACCAT GCCATCCCCC ATTATGTCAC CACATACTTG
CCACTTATGC TTGTCCTTGT GGCCAACCCG ATCCTGTTTC ACAAGACAGT GATTTCAGTG
GCCTCTTTAC TGAAAGGACG AAAAGGTGTT TATACAGAGA ATGAGAGATT GATGGGGGCC
GTGATCAAGA CCCGGTTTTT CAAAATAATG CTGGTGTTAA TTGCATGTTG GTTGTCCAAT
ATCATCAATG AATGTCTTTT GTTCTACCTT GAAATGCAAC CAGATACCCA TGGAGGCTCT
CTGAAACGCA TCCAGAATGC AGCCAGGACC ACATGGTTTA TTATGGGAAT ATTGAATCCA
TCTCAAGGAC TTCTCTTGTC TCTGGCCTTC TATGGCTGGA CAGGATGCAG CCTGGATGTC
CATGCTCCCA AGATGGTGAT TCAGTGGGAA ACAATGACTG CCTCGGCTGC TGAGGGCACA
TATCAGACCC CTGAGGGTTC CTGTGTGCCC CATCAAAACC CCAGGAAGGT GGTGTGTGTT
GGGGGGCACA CTTCTGATGA GGTGCTGAGT ATTTTGTCTG AAGGTTCGGA TGCTAGCACT
GTTGAAATCC ATACTGCAAC TGGGTCCCAC AACATAAAGG AAGTTGACTC CATTTCCCAA
GCCCAGGGGG ATCTCTGAThe stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
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PubMed
Localization of ocular albinism-1 gene product GPR143 in the rat central nervous system.
Neuroscience research8849-57(2014 Nov)
Masukawa D,Nakamura F,Koga M,Kamiya M,Chen S,Yamashita N,Arai N,Goshima Y
The protein Ocular albinism 1 is the orphan GPCR GPR143 and mediates depressor and bradycardic responses to DOPA in the nucleus tractus solitarii.
British journal of pharmacology171(2)403-14(2014 Jan)
Hiroshima Y,Miyamoto H,Nakamura F,Masukawa D,Yamamoto T,Muraoka H,Kamiya M,Yamashita N,Suzuki T,Matsuzaki S,Endo I,Goshima Y
The ocular albinism type 1 (OA1) G-protein-coupled receptor functions with MART-1 at early stages of melanogenesis to control melanosome identity and composition.
Human molecular genetics18(23)4530-45(2009 Dec)
Giordano F,Bonetti C,Surace EM,Marigo V,Raposo G
The ocular albinism type 1 protein, an intracellular G protein-coupled receptor, regulates melanosome transport in pigment cells.
Human molecular genetics17(22)3487-501(2008 Nov)
Palmisano I,Bagnato P,Palmigiano A,Innamorati G,Rotondo G,Altimare D,Venturi C,Sviderskaya EV,Piccirillo R,Coppola M,Marigo V,Incerti B,Ballabio A,Surace EM,Tacchetti C,Bennett DC,Schiaffino MV
L-DOPA is an endogenous ligand for OA1.
PLoS biology6(9)e236(2008 Sep)
Lopez VM,Decatur CL,Stamer WD,Lynch RM,McKay BS
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