Tprkb cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tprkb
Entrez Gene ID	297411
Full Name	Tp53rk binding protein
Synonyms	Cgi-121,RGD1309786
General protein information	Preferred Names Tp53rk binding protein Names EKC/KEOPS complex subunit Tprkb Prpk (p53-related protein kinase)-binding protein TP53RK-binding protein TP53RK-binding protein-like
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q34

mRNA and Protein(s)

mRNA	Protein	Name
XM_006236808.3	XP_006236870.1	EKC/KEOPS complex subunit Tprkb isoform X1
XM_017592554.1	XP_017448043.1	EKC/KEOPS complex subunit Tprkb isoform X1
NM_001013926.2	NP_001013948.2	EKC/KEOPS complex subunit Tprkb
XM_003749789.4	XP_003749837.1	EKC/KEOPS complex subunit Tprkb isoform X1
XM_017592553.1	XP_017448042.1	EKC/KEOPS complex subunit Tprkb isoform X1
XM_017592552.1	XP_017448041.1	EKC/KEOPS complex subunit Tprkb isoform X1
XM_006236805.3	XP_006236867.1	EKC/KEOPS complex subunit Tprkb isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Tprkb	NP_001163959.1
Danio rerio (zebrafish)	tprkb	NP_001007374.1
Caenorhabditis elegans (roundworm)	W03F8.4	NP_500735.1
Homo sapiens (human)	TPRKB	NP_057142.1
Canis lupus familiaris (dog)	TPRKB	XP_533004.1
Arabidopsis thaliana (thale cress)	AT4G34412	NP_680763.2
Macaca mulatta (Rhesus monkey)	TPRKB	XP_001105330.2
Gallus gallus (chicken)	TPRKB	XP_423597.2
Oryza sativa (rice)	Os01g0142200	NP_001041990.1
Bos taurus (cattle)	TPRKB	NP_001179436.1
Rattus norvegicus (Norway rat)	LOC100910911	XP_006236868.1
Pan troglodytes (chimpanzee)	TPRKB	XP_001151359.2
Rattus norvegicus (Norway rat)	Tprkb	NP_001013948.2
Xenopus tropicalis (tropical clawed frog)	tprkb	NP_989325.1

Gene Ontology
Bibliography

Related articles in PubMed

Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly.
Braun DA, Rao J, Mollet G, Schapiro D, Daugeron MC, Tan W, Gribouval O, Boyer O, Revy P, Jobst-Schwan T, Schmidt JM, Lawson JA, Schanze D, Ashraf S, Ullmann JFP, Hoogstraten CA, Boddaert N, Collinet B, Martin G, Liger D, Lovric S, Furlano M, Guerrera IC, Sanchez-Ferras O, Hu JF, Boschat AC, Sanquer S, Menten B, Vergult S, De Rocker N, Airik M, Hermle T, Shril S, Widmeier E, Gee HY, Choi WI, Sadowski CE, Pabst WL, Warejko JK, Daga A, Basta T, Matejas V, Scharmann K, Kienast SD, Behnam B, Beeson B, Begtrup A, Bruce M, Ch'ng GS, Lin SP, Chang JH, Chen CH, Cho MT, Gaffney PM, Gipson PE, Hsu CH, Kari JA, Ke YY, Kiraly-Borri C, Lai WM, Lemyre E, Littlejohn RO, Masri A, Moghtaderi M, Nakamura K, Ozaltin F, Praet M, Prasad C, Prytula A, Roeder ER, Rump P, Schnur RE, Shiihara T, Sinha MD, Soliman NA, Soulami K, Sweetser DA, Tsai WH, Tsai JD, Topaloglu R, Vester U, Viskochil DH, Vatanavicharn N, Waxler JL, Wierenga KJ, Wolf MTF, Wong SN, Leidel SA, Truglio G, Dedon PC, Poduri A, Mane S, Lifton RP, Bouchard M, Kannu P, Chitayat D, Magen D, Callewaert B, van Tilbeurgh H, Zenker M, Antignac C, Hildebrandt F
Nature genetics49(10)1529-1538(2017 Oct)

Proteomic analysis of the human KEOPS complex identifies C14ORF142 as a core subunit homologous to yeast Gon7.
Wan LC, Maisonneuve P, Szilard RK, Lambert JP, Ng TF, Manczyk N, Huang H, Laister R, Caudy AA, Gingras AC, Durocher D, Sicheri F
Nucleic acids research45(2)805-817(2017 01)

Identification of CGI-121, a novel PRPK (p53-related protein kinase)-binding protein.
Miyoshi A, Kito K, Aramoto T, Abe Y, Kobayashi N, Ueda N
Biochemical and biophysical research communications303(2)399-405(2003 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Tprkb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tprkb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa04295	NM_001013926.2 Latest version!	Rattus norvegicus Tp53rk binding protein (Tprkb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
ORa04295	XM_006236808.3 Latest version!	Rattus norvegicus Tp53rk binding protein (Tprkb), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
ORa04295	XM_017592554.1 Latest version!	Rattus norvegicus Tp53rk binding protein (Tprkb), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
ORa04295	XM_017592553.1 Latest version!	Rattus norvegicus Tp53rk binding protein (Tprkb), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
ORa04295	XM_006236805.3 Latest version!	Rattus norvegicus Tp53rk binding protein (Tprkb), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
ORa04295	XM_003749789.4 Latest version!	Rattus norvegicus Tp53rk binding protein (Tprkb), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
ORa04295	XM_017592552.1 Latest version!	Rattus norvegicus Tp53rk binding protein (Tprkb), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tprkb ( NM_001013926.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001013948.2 Rattus norvegicus Tp53rk binding protein (Tprkb), mRNA.

Price & Availability↑

CloneID	ORa04295
Clone ID Related Accession (Same CDS sequence)	XM_006236808.3 , XM_017592554.1 , NM_001013926.2 , XM_003749789.4 , XM_017592553.1 , XM_017592552.1 , XM_006236805.3
Accession Version	NM_001013926.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1555516800000
Organism	Rattus norvegicus(Norway rat)
Product	EKC/KEOPS complex subunit Tprkb
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CK475733.1. On or before Apr 21, 2005 this sequence version replaced XM_216178.2, NM_001013926.1. ##Evidence-Data-START## Transcript exon combination :: CK475733.1, EX490991.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCAGTTAA CACAGCAGCT GGACTTGTTT CCCGAGTGCA AGGTGACCCT TCTGTTATTT 
AAAGATGTAA AAAATGCAGG AGACTTGAGA AAAAAGGCCA TGGAAGGATC TATAGATGGC 
TCATTGATAA ATGCCAATGT GATTGTCGAT CCATTTCAAA TACTTGTGGC AGCAAACAAA 
GCCGTTCATC TCCACAAACT GGGAAAAATG AAGACAAGAA CTCTGTCTAC TGAAATTATC 
TTCAACCTCT CCCCAAATAA TAATATTTCA GAGGCTTTGA AGAAGTTTGG CATCTCAGAA 
AGTAACACTT CAGTTCTGAT TGTTTATGTT GAAGATGGAG ACAAACAAGT GCATCAGGAA 
CACCTAGTAT CTCAAGTGGA AGGCCAGCAG GTGCCCTTGG AAAGTCTTCC TGAAATAACA 
AGGCTCTCAG AAGTCAGGAA GATATATAAA CTGTCATCAC AAGAAGAGAG GATTGGGACA 
TTATTGGATG GTATCATTTG TAGAATGTCA ACAAAGGATG TTTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001013948.2
CDS	121..648
Translation	MQLTQQLDLFPECKVTLLLFKDVKNAGDLRKKAMEGSIDGSLINANVIVDPFQILVAANKAVHLHKLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISESNTSVLIVYVEDGDKQVHQEHLVSQVEGQQVPLESLPEITRLSEVRKIYKLSSQEERIGTLLDGIICRMSTKDVL

Target ORF information:

RefSeq Version	NM_001013926.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Tp53rk binding protein (Tprkb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001013926.2

ORF Insert Sequence:

ATGCAGTTAA CACAGCAGCT GGACTTGTTT CCCGAGTGCA AGGTGACCCT TCTGTTATTT 
AAAGATGTAA AAAATGCAGG AGACTTGAGA AAAAAGGCCA TGGAAGGATC TATAGATGGC 
TCATTGATAA ATGCCAATGT GATTGTCGAT CCATTTCAAA TACTTGTGGC AGCAAACAAA 
GCCGTTCATC TCCACAAACT GGGAAAAATG AAGACAAGAA CTCTGTCTAC TGAAATTATC 
TTCAACCTCT CCCCAAATAA TAATATTTCA GAGGCTTTGA AGAAGTTTGG CATCTCAGAA 
AGTAACACTT CAGTTCTGAT TGTTTATGTT GAAGATGGAG ACAAACAAGT GCATCAGGAA 
CACCTAGTAT CTCAAGTGGA AGGCCAGCAG GTGCCCTTGG AAAGTCTTCC TGAAATAACA 
AGGCTCTCAG AAGTCAGGAA GATATATAAA CTGTCATCAC AAGAAGAGAG GATTGGGACA 
TTATTGGATG GTATCATTTG TAGAATGTCA ACAAAGGATG TTTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tprkb ( XM_006236808.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006236870.1 Rattus norvegicus Tp53rk binding protein (Tprkb), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa04295
Clone ID Related Accession (Same CDS sequence)	XM_006236808.3 , XM_017592554.1 , NM_001013926.2 , XM_003749789.4 , XM_017592553.1 , XM_017592552.1 , XM_006236805.3
Accession Version	XM_006236808.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	EKC/KEOPS complex subunit Tprkb isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006236808.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGTTAA CACAGCAGCT GGACTTGTTT CCCGAGTGCA AGGTGACCCT TCTGTTATTT 
AAAGATGTAA AAAATGCAGG AGACTTGAGA AAAAAGGCCA TGGAAGGATC TATAGATGGC 
TCATTGATAA ATGCCAATGT GATTGTCGAT CCATTTCAAA TACTTGTGGC AGCAAACAAA 
GCCGTTCATC TCCACAAACT GGGAAAAATG AAGACAAGAA CTCTGTCTAC TGAAATTATC 
TTCAACCTCT CCCCAAATAA TAATATTTCA GAGGCTTTGA AGAAGTTTGG CATCTCAGAA 
AGTAACACTT CAGTTCTGAT TGTTTATGTT GAAGATGGAG ACAAACAAGT GCATCAGGAA 
CACCTAGTAT CTCAAGTGGA AGGCCAGCAG GTGCCCTTGG AAAGTCTTCC TGAAATAACA 
AGGCTCTCAG AAGTCAGGAA GATATATAAA CTGTCATCAC AAGAAGAGAG GATTGGGACA 
TTATTGGATG GTATCATTTG TAGAATGTCA ACAAAGGATG TTTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006236870.1
CDS	189..716
Translation	MQLTQQLDLFPECKVTLLLFKDVKNAGDLRKKAMEGSIDGSLINANVIVDPFQILVAANKAVHLHKLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISESNTSVLIVYVEDGDKQVHQEHLVSQVEGQQVPLESLPEITRLSEVRKIYKLSSQEERIGTLLDGIICRMSTKDVL

Target ORF information:

RefSeq Version	XM_006236808.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Tp53rk binding protein (Tprkb), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006236808.3

ORF Insert Sequence:

ATGCAGTTAA CACAGCAGCT GGACTTGTTT CCCGAGTGCA AGGTGACCCT TCTGTTATTT 
AAAGATGTAA AAAATGCAGG AGACTTGAGA AAAAAGGCCA TGGAAGGATC TATAGATGGC 
TCATTGATAA ATGCCAATGT GATTGTCGAT CCATTTCAAA TACTTGTGGC AGCAAACAAA 
GCCGTTCATC TCCACAAACT GGGAAAAATG AAGACAAGAA CTCTGTCTAC TGAAATTATC 
TTCAACCTCT CCCCAAATAA TAATATTTCA GAGGCTTTGA AGAAGTTTGG CATCTCAGAA 
AGTAACACTT CAGTTCTGAT TGTTTATGTT GAAGATGGAG ACAAACAAGT GCATCAGGAA 
CACCTAGTAT CTCAAGTGGA AGGCCAGCAG GTGCCCTTGG AAAGTCTTCC TGAAATAACA 
AGGCTCTCAG AAGTCAGGAA GATATATAAA CTGTCATCAC AAGAAGAGAG GATTGGGACA 
TTATTGGATG GTATCATTTG TAGAATGTCA ACAAAGGATG TTTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tprkb ( XM_017592554.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017448043.1 Rattus norvegicus Tp53rk binding protein (Tprkb), transcript variant X6, mRNA.

Price & Availability↑

CloneID	ORa04295
Clone ID Related Accession (Same CDS sequence)	XM_006236808.3 , XM_017592554.1 , NM_001013926.2 , XM_003749789.4 , XM_017592553.1 , XM_017592552.1 , XM_006236805.3
Accession Version	XM_017592554.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	EKC/KEOPS complex subunit Tprkb isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGTTAA CACAGCAGCT GGACTTGTTT CCCGAGTGCA AGGTGACCCT TCTGTTATTT 
AAAGATGTAA AAAATGCAGG AGACTTGAGA AAAAAGGCCA TGGAAGGATC TATAGATGGC 
TCATTGATAA ATGCCAATGT GATTGTCGAT CCATTTCAAA TACTTGTGGC AGCAAACAAA 
GCCGTTCATC TCCACAAACT GGGAAAAATG AAGACAAGAA CTCTGTCTAC TGAAATTATC 
TTCAACCTCT CCCCAAATAA TAATATTTCA GAGGCTTTGA AGAAGTTTGG CATCTCAGAA 
AGTAACACTT CAGTTCTGAT TGTTTATGTT GAAGATGGAG ACAAACAAGT GCATCAGGAA 
CACCTAGTAT CTCAAGTGGA AGGCCAGCAG GTGCCCTTGG AAAGTCTTCC TGAAATAACA 
AGGCTCTCAG AAGTCAGGAA GATATATAAA CTGTCATCAC AAGAAGAGAG GATTGGGACA 
TTATTGGATG GTATCATTTG TAGAATGTCA ACAAAGGATG TTTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017448043.1
CDS	73..600
Translation	MQLTQQLDLFPECKVTLLLFKDVKNAGDLRKKAMEGSIDGSLINANVIVDPFQILVAANKAVHLHKLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISESNTSVLIVYVEDGDKQVHQEHLVSQVEGQQVPLESLPEITRLSEVRKIYKLSSQEERIGTLLDGIICRMSTKDVL

Target ORF information:

RefSeq Version	XM_017592554.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Tp53rk binding protein (Tprkb), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017592554.1

ORF Insert Sequence:

ATGCAGTTAA CACAGCAGCT GGACTTGTTT CCCGAGTGCA AGGTGACCCT TCTGTTATTT 
AAAGATGTAA AAAATGCAGG AGACTTGAGA AAAAAGGCCA TGGAAGGATC TATAGATGGC 
TCATTGATAA ATGCCAATGT GATTGTCGAT CCATTTCAAA TACTTGTGGC AGCAAACAAA 
GCCGTTCATC TCCACAAACT GGGAAAAATG AAGACAAGAA CTCTGTCTAC TGAAATTATC 
TTCAACCTCT CCCCAAATAA TAATATTTCA GAGGCTTTGA AGAAGTTTGG CATCTCAGAA 
AGTAACACTT CAGTTCTGAT TGTTTATGTT GAAGATGGAG ACAAACAAGT GCATCAGGAA 
CACCTAGTAT CTCAAGTGGA AGGCCAGCAG GTGCCCTTGG AAAGTCTTCC TGAAATAACA 
AGGCTCTCAG AAGTCAGGAA GATATATAAA CTGTCATCAC AAGAAGAGAG GATTGGGACA 
TTATTGGATG GTATCATTTG TAGAATGTCA ACAAAGGATG TTTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tprkb ( XM_003749789.4 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_003749837.1 Rattus norvegicus Tp53rk binding protein (Tprkb), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa04295
Clone ID Related Accession (Same CDS sequence)	XM_006236808.3 , XM_017592554.1 , NM_001013926.2 , XM_003749789.4 , XM_017592553.1 , XM_017592552.1 , XM_006236805.3
Accession Version	XM_003749789.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	EKC/KEOPS complex subunit Tprkb isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_003749789.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGTTAA CACAGCAGCT GGACTTGTTT CCCGAGTGCA AGGTGACCCT TCTGTTATTT 
AAAGATGTAA AAAATGCAGG AGACTTGAGA AAAAAGGCCA TGGAAGGATC TATAGATGGC 
TCATTGATAA ATGCCAATGT GATTGTCGAT CCATTTCAAA TACTTGTGGC AGCAAACAAA 
GCCGTTCATC TCCACAAACT GGGAAAAATG AAGACAAGAA CTCTGTCTAC TGAAATTATC 
TTCAACCTCT CCCCAAATAA TAATATTTCA GAGGCTTTGA AGAAGTTTGG CATCTCAGAA 
AGTAACACTT CAGTTCTGAT TGTTTATGTT GAAGATGGAG ACAAACAAGT GCATCAGGAA 
CACCTAGTAT CTCAAGTGGA AGGCCAGCAG GTGCCCTTGG AAAGTCTTCC TGAAATAACA 
AGGCTCTCAG AAGTCAGGAA GATATATAAA CTGTCATCAC AAGAAGAGAG GATTGGGACA 
TTATTGGATG GTATCATTTG TAGAATGTCA ACAAAGGATG TTTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_003749837.1
CDS	110..637
Translation	MQLTQQLDLFPECKVTLLLFKDVKNAGDLRKKAMEGSIDGSLINANVIVDPFQILVAANKAVHLHKLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISESNTSVLIVYVEDGDKQVHQEHLVSQVEGQQVPLESLPEITRLSEVRKIYKLSSQEERIGTLLDGIICRMSTKDVL

Target ORF information:

RefSeq Version	XM_003749789.4
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Tp53rk binding protein (Tprkb), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_003749789.4

ORF Insert Sequence:

ATGCAGTTAA CACAGCAGCT GGACTTGTTT CCCGAGTGCA AGGTGACCCT TCTGTTATTT 
AAAGATGTAA AAAATGCAGG AGACTTGAGA AAAAAGGCCA TGGAAGGATC TATAGATGGC 
TCATTGATAA ATGCCAATGT GATTGTCGAT CCATTTCAAA TACTTGTGGC AGCAAACAAA 
GCCGTTCATC TCCACAAACT GGGAAAAATG AAGACAAGAA CTCTGTCTAC TGAAATTATC 
TTCAACCTCT CCCCAAATAA TAATATTTCA GAGGCTTTGA AGAAGTTTGG CATCTCAGAA 
AGTAACACTT CAGTTCTGAT TGTTTATGTT GAAGATGGAG ACAAACAAGT GCATCAGGAA 
CACCTAGTAT CTCAAGTGGA AGGCCAGCAG GTGCCCTTGG AAAGTCTTCC TGAAATAACA 
AGGCTCTCAG AAGTCAGGAA GATATATAAA CTGTCATCAC AAGAAGAGAG GATTGGGACA 
TTATTGGATG GTATCATTTG TAGAATGTCA ACAAAGGATG TTTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tprkb ( XM_017592553.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017448042.1 Rattus norvegicus Tp53rk binding protein (Tprkb), transcript variant X5, mRNA.

Price & Availability↑

CloneID	ORa04295
Clone ID Related Accession (Same CDS sequence)	XM_006236808.3 , XM_017592554.1 , NM_001013926.2 , XM_003749789.4 , XM_017592553.1 , XM_017592552.1 , XM_006236805.3
Accession Version	XM_017592553.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	EKC/KEOPS complex subunit Tprkb isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGTTAA CACAGCAGCT GGACTTGTTT CCCGAGTGCA AGGTGACCCT TCTGTTATTT 
AAAGATGTAA AAAATGCAGG AGACTTGAGA AAAAAGGCCA TGGAAGGATC TATAGATGGC 
TCATTGATAA ATGCCAATGT GATTGTCGAT CCATTTCAAA TACTTGTGGC AGCAAACAAA 
GCCGTTCATC TCCACAAACT GGGAAAAATG AAGACAAGAA CTCTGTCTAC TGAAATTATC 
TTCAACCTCT CCCCAAATAA TAATATTTCA GAGGCTTTGA AGAAGTTTGG CATCTCAGAA 
AGTAACACTT CAGTTCTGAT TGTTTATGTT GAAGATGGAG ACAAACAAGT GCATCAGGAA 
CACCTAGTAT CTCAAGTGGA AGGCCAGCAG GTGCCCTTGG AAAGTCTTCC TGAAATAACA 
AGGCTCTCAG AAGTCAGGAA GATATATAAA CTGTCATCAC AAGAAGAGAG GATTGGGACA 
TTATTGGATG GTATCATTTG TAGAATGTCA ACAAAGGATG TTTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017448042.1
CDS	185..712
Translation	MQLTQQLDLFPECKVTLLLFKDVKNAGDLRKKAMEGSIDGSLINANVIVDPFQILVAANKAVHLHKLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISESNTSVLIVYVEDGDKQVHQEHLVSQVEGQQVPLESLPEITRLSEVRKIYKLSSQEERIGTLLDGIICRMSTKDVL

Target ORF information:

RefSeq Version	XM_017592553.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Tp53rk binding protein (Tprkb), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017592553.1

ORF Insert Sequence:

ATGCAGTTAA CACAGCAGCT GGACTTGTTT CCCGAGTGCA AGGTGACCCT TCTGTTATTT 
AAAGATGTAA AAAATGCAGG AGACTTGAGA AAAAAGGCCA TGGAAGGATC TATAGATGGC 
TCATTGATAA ATGCCAATGT GATTGTCGAT CCATTTCAAA TACTTGTGGC AGCAAACAAA 
GCCGTTCATC TCCACAAACT GGGAAAAATG AAGACAAGAA CTCTGTCTAC TGAAATTATC 
TTCAACCTCT CCCCAAATAA TAATATTTCA GAGGCTTTGA AGAAGTTTGG CATCTCAGAA 
AGTAACACTT CAGTTCTGAT TGTTTATGTT GAAGATGGAG ACAAACAAGT GCATCAGGAA 
CACCTAGTAT CTCAAGTGGA AGGCCAGCAG GTGCCCTTGG AAAGTCTTCC TGAAATAACA 
AGGCTCTCAG AAGTCAGGAA GATATATAAA CTGTCATCAC AAGAAGAGAG GATTGGGACA 
TTATTGGATG GTATCATTTG TAGAATGTCA ACAAAGGATG TTTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tprkb ( XM_017592552.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017448041.1 Rattus norvegicus Tp53rk binding protein (Tprkb), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa04295
Clone ID Related Accession (Same CDS sequence)	XM_006236808.3 , XM_017592554.1 , NM_001013926.2 , XM_003749789.4 , XM_017592553.1 , XM_017592552.1 , XM_006236805.3
Accession Version	XM_017592552.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	EKC/KEOPS complex subunit Tprkb isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGTTAA CACAGCAGCT GGACTTGTTT CCCGAGTGCA AGGTGACCCT TCTGTTATTT 
AAAGATGTAA AAAATGCAGG AGACTTGAGA AAAAAGGCCA TGGAAGGATC TATAGATGGC 
TCATTGATAA ATGCCAATGT GATTGTCGAT CCATTTCAAA TACTTGTGGC AGCAAACAAA 
GCCGTTCATC TCCACAAACT GGGAAAAATG AAGACAAGAA CTCTGTCTAC TGAAATTATC 
TTCAACCTCT CCCCAAATAA TAATATTTCA GAGGCTTTGA AGAAGTTTGG CATCTCAGAA 
AGTAACACTT CAGTTCTGAT TGTTTATGTT GAAGATGGAG ACAAACAAGT GCATCAGGAA 
CACCTAGTAT CTCAAGTGGA AGGCCAGCAG GTGCCCTTGG AAAGTCTTCC TGAAATAACA 
AGGCTCTCAG AAGTCAGGAA GATATATAAA CTGTCATCAC AAGAAGAGAG GATTGGGACA 
TTATTGGATG GTATCATTTG TAGAATGTCA ACAAAGGATG TTTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017448041.1
CDS	776..1303
Translation	MQLTQQLDLFPECKVTLLLFKDVKNAGDLRKKAMEGSIDGSLINANVIVDPFQILVAANKAVHLHKLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISESNTSVLIVYVEDGDKQVHQEHLVSQVEGQQVPLESLPEITRLSEVRKIYKLSSQEERIGTLLDGIICRMSTKDVL

Target ORF information:

RefSeq Version	XM_017592552.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Tp53rk binding protein (Tprkb), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017592552.1

ORF Insert Sequence:

ATGCAGTTAA CACAGCAGCT GGACTTGTTT CCCGAGTGCA AGGTGACCCT TCTGTTATTT 
AAAGATGTAA AAAATGCAGG AGACTTGAGA AAAAAGGCCA TGGAAGGATC TATAGATGGC 
TCATTGATAA ATGCCAATGT GATTGTCGAT CCATTTCAAA TACTTGTGGC AGCAAACAAA 
GCCGTTCATC TCCACAAACT GGGAAAAATG AAGACAAGAA CTCTGTCTAC TGAAATTATC 
TTCAACCTCT CCCCAAATAA TAATATTTCA GAGGCTTTGA AGAAGTTTGG CATCTCAGAA 
AGTAACACTT CAGTTCTGAT TGTTTATGTT GAAGATGGAG ACAAACAAGT GCATCAGGAA 
CACCTAGTAT CTCAAGTGGA AGGCCAGCAG GTGCCCTTGG AAAGTCTTCC TGAAATAACA 
AGGCTCTCAG AAGTCAGGAA GATATATAAA CTGTCATCAC AAGAAGAGAG GATTGGGACA 
TTATTGGATG GTATCATTTG TAGAATGTCA ACAAAGGATG TTTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tprkb ( XM_006236805.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006236867.1 Rattus norvegicus Tp53rk binding protein (Tprkb), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa04295
Clone ID Related Accession (Same CDS sequence)	XM_006236808.3 , XM_017592554.1 , NM_001013926.2 , XM_003749789.4 , XM_017592553.1 , XM_017592552.1 , XM_006236805.3
Accession Version	XM_006236805.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	EKC/KEOPS complex subunit Tprkb isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006236805.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGTTAA CACAGCAGCT GGACTTGTTT CCCGAGTGCA AGGTGACCCT TCTGTTATTT 
AAAGATGTAA AAAATGCAGG AGACTTGAGA AAAAAGGCCA TGGAAGGATC TATAGATGGC 
TCATTGATAA ATGCCAATGT GATTGTCGAT CCATTTCAAA TACTTGTGGC AGCAAACAAA 
GCCGTTCATC TCCACAAACT GGGAAAAATG AAGACAAGAA CTCTGTCTAC TGAAATTATC 
TTCAACCTCT CCCCAAATAA TAATATTTCA GAGGCTTTGA AGAAGTTTGG CATCTCAGAA 
AGTAACACTT CAGTTCTGAT TGTTTATGTT GAAGATGGAG ACAAACAAGT GCATCAGGAA 
CACCTAGTAT CTCAAGTGGA AGGCCAGCAG GTGCCCTTGG AAAGTCTTCC TGAAATAACA 
AGGCTCTCAG AAGTCAGGAA GATATATAAA CTGTCATCAC AAGAAGAGAG GATTGGGACA 
TTATTGGATG GTATCATTTG TAGAATGTCA ACAAAGGATG TTTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006236867.1
CDS	344..871
Translation	MQLTQQLDLFPECKVTLLLFKDVKNAGDLRKKAMEGSIDGSLINANVIVDPFQILVAANKAVHLHKLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISESNTSVLIVYVEDGDKQVHQEHLVSQVEGQQVPLESLPEITRLSEVRKIYKLSSQEERIGTLLDGIICRMSTKDVL

Target ORF information:

RefSeq Version	XM_006236805.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Tp53rk binding protein (Tprkb), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006236805.3

ORF Insert Sequence:

ATGCAGTTAA CACAGCAGCT GGACTTGTTT CCCGAGTGCA AGGTGACCCT TCTGTTATTT 
AAAGATGTAA AAAATGCAGG AGACTTGAGA AAAAAGGCCA TGGAAGGATC TATAGATGGC 
TCATTGATAA ATGCCAATGT GATTGTCGAT CCATTTCAAA TACTTGTGGC AGCAAACAAA 
GCCGTTCATC TCCACAAACT GGGAAAAATG AAGACAAGAA CTCTGTCTAC TGAAATTATC 
TTCAACCTCT CCCCAAATAA TAATATTTCA GAGGCTTTGA AGAAGTTTGG CATCTCAGAA 
AGTAACACTT CAGTTCTGAT TGTTTATGTT GAAGATGGAG ACAAACAAGT GCATCAGGAA 
CACCTAGTAT CTCAAGTGGA AGGCCAGCAG GTGCCCTTGG AAAGTCTTCC TGAAATAACA 
AGGCTCTCAG AAGTCAGGAA GATATATAAA CTGTCATCAC AAGAAGAGAG GATTGGGACA 
TTATTGGATG GTATCATTTG TAGAATGTCA ACAAAGGATG TTTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly.
Nature genetics49(10)1529-1538(2017 Oct)
Braun DA,Rao J,Mollet G,Schapiro D,Daugeron MC,Tan W,Gribouval O,Boyer O,Revy P,Jobst-Schwan T,Schmidt JM,Lawson JA,Schanze D,Ashraf S,Ullmann JFP,Hoogstraten CA,Boddaert N,Collinet B,Martin G,Liger D,Lovric S,Furlano M,Guerrera IC,Sanchez-Ferras O,Hu JF,Boschat AC,Sanquer S,Menten B,Vergult S,De Rocker N,Airik M,Hermle T,Shril S,Widmeier E,Gee HY,Choi WI,Sadowski CE,Pabst WL,Warejko JK,Daga A,Basta T,Matejas V,Scharmann K,Kienast SD,Behnam B,Beeson B,Begtrup A,Bruce M,Ch'ng GS,Lin SP,Chang JH,Chen CH,Cho MT,Gaffney PM,Gipson PE,Hsu CH,Kari JA,Ke YY,Kiraly-Borri C,Lai WM,Lemyre E,Littlejohn RO,Masri A,Moghtaderi M,Nakamura K,Ozaltin F,Praet M,Prasad C,Prytula A,Roeder ER,Rump P,Schnur RE,Shiihara T,Sinha MD,Soliman NA,Soulami K,Sweetser DA,Tsai WH,Tsai JD,Topaloglu R,Vester U,Viskochil DH,Vatanavicharn N,Waxler JL,Wierenga KJ,Wolf MTF,Wong SN,Leidel SA,Truglio G,Dedon PC,Poduri A,Mane S,Lifton RP,Bouchard M,Kannu P,Chitayat D,Magen D,Callewaert B,van Tilbeurgh H,Zenker M,Antignac C,Hildebrandt F

Proteomic analysis of the human KEOPS complex identifies C14ORF142 as a core subunit homologous to yeast Gon7.
Nucleic acids research45(2)805-817(2017 01)
Wan LC,Maisonneuve P,Szilard RK,Lambert JP,Ng TF,Manczyk N,Huang H,Laister R,Caudy AA,Gingras AC,Durocher D,Sicheri F

Identification of CGI-121, a novel PRPK (p53-related protein kinase)-binding protein.
Biochemical and biophysical research communications303(2)399-405(2003 Apr)
Miyoshi A,Kito K,Aramoto T,Abe Y,Kobayashi N,Ueda N

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Tprkb cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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