Hmgcs1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hmgcs1
Entrez Gene ID	29637
Full Name	3-hydroxy-3-methylglutaryl-CoA synthase 1
General protein information	Preferred Names 3-hydroxy-3-methylglutaryl-CoA synthase 1 Names hydroxymethylglutaryl-CoA synthase, cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A synthase 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) HMG-CoA synthase hydroxymethylglutaryl-CoA synthase 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q15
Summary	catalyzes the conversion of (S)-3-hydroxy-3-methylglutaryl-CoA and CoA to acetyl-CoA, acetoacetyl-CoA, and H2O [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_017268.1	NP_058964.1	hydroxymethylglutaryl-CoA synthase, cytoplasmic
XM_006231959.2	XP_006232021.1	hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X1

Pathways from BioSystems

Homologies

Oryza sativa (rice)	Os08g0544900	NP_001062410.1
Kluyveromyces lactis	KLLA0D10505g	XP_453529.2
Mus musculus (house mouse)	Hmgcs1	NP_666054.2
Eremothecium gossypii	AGOS_ADL356C	NP_983739.1
Magnaporthe oryzae (rice blast fungus)	MGG_01026	XP_003717917.1
Neurospora crassa	NCU03922	XP_957561.1
Oryza sativa (rice)	Os09g0521400	NP_001063706.1
Canis lupus familiaris (dog)	HMGCS1	XP_005619400.1
Bos taurus (cattle)	HMGCS1	NP_001193507.1
Danio rerio (zebrafish)	hmgcs1	NP_957379.1
Arabidopsis thaliana (thale cress)	MVA1	NP_192919.1
Oryza sativa (rice)	Os03g0118800	NP_001048774.1
Macaca mulatta (Rhesus monkey)	HMGCS1	XP_002804403.1
Saccharomyces cerevisiae (baker's yeast)	ERG13	NP_013580.1
Xenopus tropicalis (tropical clawed frog)	hmgcs1	NP_001120172.1
Homo sapiens (human)	HMGCS1	NP_001091742.1
Rattus norvegicus (Norway rat)	Hmgcs1	NP_058964.1
Pan troglodytes (chimpanzee)	HMGCS1	XP_003310783.1
Gallus gallus (chicken)	HMGCS1	NP_990742.1
Drosophila melanogaster (fruit fly)	Hmgs	NP_725570.1
Schizosaccharomyces pombe (fission yeast)	hcs1	NP_593859.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005847	XP_315872.3

Gene Ontology
Bibliography

Related articles in PubMed

HMG-CoA synthase isoenzymes 1 and 2 localize to satellite glial cells in dorsal root ganglia and are differentially regulated by peripheral nerve injury.
Wang F, Xiang H, Fischer G, Liu Z, Dupont MJ, Hogan QH, Yu H
Brain research165262-70(2016 12)

Proteomic profiling of proteins in rat spinal cord induced by contusion injury.
Yan X, Liu J, Luo Z, Ding Q, Mao X, Yan M, Yang S, Hu X, Huang J, Luo Z
Neurochemistry international56(8)971-83(2010 Jul)

Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design.
Shafqat N, Turnbull A, Zschocke J, Oppermann U, Yue WW
Journal of molecular biology398(4)497-506(2010 May)

Actein activates stress- and statin-associated responses and is bioavailable in Sprague-Dawley rats.
Einbond LS, Soffritti M, Esposti DD, Park T, Cruz E, Su T, Wu HA, Wang X, Zhang YJ, Ham J, Goldberg IJ, Kronenberg F, Vladimirova A
Fundamental & clinical pharmacology23(3)311-21(2009 Jun)

FSH and FOXO1 regulate genes in the sterol/steroid and lipid biosynthetic pathways in granulosa cells.
Liu Z, Rudd MD, Hernandez-Gonzalez I, Gonzalez-Robayna I, Fan HY, Zeleznik AJ, Richards JS
Molecular endocrinology (Baltimore, Md.)23(5)649-61(2009 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Hmgcs1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hmgcs1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03473	NM_017268.1 Latest version!	Rattus norvegicus 3-hydroxy-3-methylglutaryl-CoA synthase 1 (Hmgcs1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa03473	XM_006231959.2 Latest version!	Rattus norvegicus 3-hydroxy-3-methylglutaryl-CoA synthase 1 (Hmgcs1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hmgcs1 ( NM_017268.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_058964.1 Rattus norvegicus 3-hydroxy-3-methylglutaryl-CoA synthase 1 (Hmgcs1), mRNA.

Price & Availability↑

CloneID	ORa03473
Clone ID Related Accession (Same CDS sequence)	NM_017268.1 , XM_006231959.2
Accession Version	NM_017268.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1563bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577203200000
Organism	Rattus norvegicus(Norway rat)
Product	hydroxymethylglutaryl-CoA synthase, cytoplasmic
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X52625.1. On Dec 17, 2003 this sequence version replaced XM_346614.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X52625.1, AY724522.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCCTGGGT CACTTCCTTT GAATGCAGAG GCTTGCTGGC CAAAAGATGT GGGAATCGTT 
GCCCTTGAAA TCTACTTTCC TTCTCAGTAT GTTGATCAAG CTGAGTTGGA AAAATACGAT 
GGTGTAGATG CTGGAAAGTA TACCATTGGC CTGGGCCAGG CCAGGATGGG CTTCTGCACG 
GATCGCGAAG ACATCAACTC TCTCTGCCTG ACTGTGGTTC AGAAACTGAT GGAGAGAAAT 
AGCCTTTCCT ATGACTGCAT TGGGCGGCTG GAAGTCGGGA CAGAGACAAT CATCGACAAA 
TCAAAATCCG TGAAGTCTAA TTTGATGCAG CTGTTTGAGG AGTCTGGGAA TACAGATATA 
GAAGGAATAG ATACAACTAA TGCATGCTAT GGGGGCACAG CCGCAGTCTT CAATGCTGTG 
AACTGGATCG AATCCAGCTC TTGGGATGGA CGATACGCTT TGGTAGTTGC AGGAGACATC 
GCTATATATG CCTCAGGAAA CGCCAGGCCT ACAGGTGGAG TTGGAGCTGT GGCTCTGCTA 
ATTGGGCCAA ATGCTCCTGT AATTTTTGAC CGAGGGCTTC GTGGGACACA CATGCAGCAT 
GCCTACGACT TTTACAAGCC TGACATGCTC TCTGAATACC CTGTGGTAGA TGGAAAACTC 
TCCATACAGT GCTACCTCAG CGCATTGGAC CGCTGCTATT CTGTCTACCG CAAAAAGATC 
CGGGCCCAGT GGCAGAAAGA GGGAAAGGAT AAAGATTTTA CCCTGAATGA TTTTGGCTTC 
ATGATCTTTC ACTCGCCATA CTGTAAACTG GTGCAGAAAT CTCTAGCTAG GATGTTCCTG 
AATGACTTTC TTAACGATCA AAACAGAGAC AAAAACAGTA TTTACAGTGG GCTGGAAGCC 
TTTGGGGATG TGAAATTAGA AGATACTTAC TTCGACAGAG ATGTGGAAAA GGCATTTATG 
AAGGCTAGTG CTGAGCTATT CAACCAGAAA ACAAAGGCAT CTTTGCTTGT ATCGAATCAA 
AATGGAAACA TGTACACATC CTCTGTATAC GGTTCCCTTG CTTCTGTTCT GGCACAGTAC 
TCACCTCAAC AGTTGGCCGG GAAGAGGATT GGAGTGTTCT CTTACGGTTC TGGCTTGGCT 
GCCACACTCT ACTCCCTTAA AGTCACACAA GATGCCACAC CAGGATCTGC TCTTGACAAA 
ATAACAGCAA GTTTATGTGA CCTTAAGTCA AGGCTTGACT CAAGAACGTG TGTGGCACCA 
GACGTCTTTG CTGAAAACAT GAAGCTCAGA GAGGACACAC ATCACTTAGC CAACTATATT 
CCCCAGTGTT CAATAGATTC ACTCTTCGAA GGAACATGGT ATCTAGTCAG AGTGGATGAA 
AAGCACAGAA GAACTTACGC CCGGCGTCCC TCCACAAATG ACCACAGTTT GGATGAAGGA 
GTGGGACTTG TGCATTCAAA CACAGCTACA GAGCATATTC CAAGCCCGGC TAAGAAAGTG 
CCAAGACTTC CTGCGACCTC GGGCGAACCT GAGTCGGCTG TCATCAGTAA CGGGGAGCAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058964.1
CDS	92..1654
Translation	MPGSLPLNAEACWPKDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQARMGFCTDREDINSLCLTVVQKLMERNSLSYDCIGRLEVGTETIIDKSKSVKSNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAIYASGNARPTGGVGAVALLIGPNAPVIFDRGLRGTHMQHAYDFYKPDMLSEYPVVDGKLSIQCYLSALDRCYSVYRKKIRAQWQKEGKDKDFTLNDFGFMIFHSPYCKLVQKSLARMFLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRDVEKAFMKASAELFNQKTKASLLVSNQNGNMYTSSVYGSLASVLAQYSPQQLAGKRIGVFSYGSGLAATLYSLKVTQDATPGSALDKITASLCDLKSRLDSRTCVAPDVFAENMKLREDTHHLANYIPQCSIDSLFEGTWYLVRVDEKHRRTYARRPSTNDHSLDEGVGLVHSNTATEHIPSPAKKVPRLPATSGEPESAVISNGEH

Target ORF information:

RefSeq Version	NM_017268.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus 3-hydroxy-3-methylglutaryl-CoA synthase 1 (Hmgcs1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017268.1

ORF Insert Sequence:

ATGCCTGGGT CACTTCCTTT GAATGCAGAG GCTTGCTGGC CAAAAGATGT GGGAATCGTT 
GCCCTTGAAA TCTACTTTCC TTCTCAGTAT GTTGATCAAG CTGAGTTGGA AAAATACGAT 
GGTGTAGATG CTGGAAAGTA TACCATTGGC CTGGGCCAGG CCAGGATGGG CTTCTGCACG 
GATCGCGAAG ACATCAACTC TCTCTGCCTG ACTGTGGTTC AGAAACTGAT GGAGAGAAAT 
AGCCTTTCCT ATGACTGCAT TGGGCGGCTG GAAGTCGGGA CAGAGACAAT CATCGACAAA 
TCAAAATCCG TGAAGTCTAA TTTGATGCAG CTGTTTGAGG AGTCTGGGAA TACAGATATA 
GAAGGAATAG ATACAACTAA TGCATGCTAT GGGGGCACAG CCGCAGTCTT CAATGCTGTG 
AACTGGATCG AATCCAGCTC TTGGGATGGA CGATACGCTT TGGTAGTTGC AGGAGACATC 
GCTATATATG CCTCAGGAAA CGCCAGGCCT ACAGGTGGAG TTGGAGCTGT GGCTCTGCTA 
ATTGGGCCAA ATGCTCCTGT AATTTTTGAC CGAGGGCTTC GTGGGACACA CATGCAGCAT 
GCCTACGACT TTTACAAGCC TGACATGCTC TCTGAATACC CTGTGGTAGA TGGAAAACTC 
TCCATACAGT GCTACCTCAG CGCATTGGAC CGCTGCTATT CTGTCTACCG CAAAAAGATC 
CGGGCCCAGT GGCAGAAAGA GGGAAAGGAT AAAGATTTTA CCCTGAATGA TTTTGGCTTC 
ATGATCTTTC ACTCGCCATA CTGTAAACTG GTGCAGAAAT CTCTAGCTAG GATGTTCCTG 
AATGACTTTC TTAACGATCA AAACAGAGAC AAAAACAGTA TTTACAGTGG GCTGGAAGCC 
TTTGGGGATG TGAAATTAGA AGATACTTAC TTCGACAGAG ATGTGGAAAA GGCATTTATG 
AAGGCTAGTG CTGAGCTATT CAACCAGAAA ACAAAGGCAT CTTTGCTTGT ATCGAATCAA 
AATGGAAACA TGTACACATC CTCTGTATAC GGTTCCCTTG CTTCTGTTCT GGCACAGTAC 
TCACCTCAAC AGTTGGCCGG GAAGAGGATT GGAGTGTTCT CTTACGGTTC TGGCTTGGCT 
GCCACACTCT ACTCCCTTAA AGTCACACAA GATGCCACAC CAGGATCTGC TCTTGACAAA 
ATAACAGCAA GTTTATGTGA CCTTAAGTCA AGGCTTGACT CAAGAACGTG TGTGGCACCA 
GACGTCTTTG CTGAAAACAT GAAGCTCAGA GAGGACACAC ATCACTTAGC CAACTATATT 
CCCCAGTGTT CAATAGATTC ACTCTTCGAA GGAACATGGT ATCTAGTCAG AGTGGATGAA 
AAGCACAGAA GAACTTACGC CCGGCGTCCC TCCACAAATG ACCACAGTTT GGATGAAGGA 
GTGGGACTTG TGCATTCAAA CACAGCTACA GAGCATATTC CAAGCCCGGC TAAGAAAGTG 
CCAAGACTTC CTGCGACCTC GGGCGAACCT GAGTCGGCTG TCATCAGTAA CGGGGAGCAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Hmgcs1 ( XM_006231959.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006232021.1 Rattus norvegicus 3-hydroxy-3-methylglutaryl-CoA synthase 1 (Hmgcs1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa03473
Clone ID Related Accession (Same CDS sequence)	NM_017268.1 , XM_006231959.2
Accession Version	XM_006231959.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1563bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231959.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTGGGT CACTTCCTTT GAATGCAGAG GCTTGCTGGC CAAAAGATGT GGGAATCGTT 
GCCCTTGAAA TCTACTTTCC TTCTCAGTAT GTTGATCAAG CTGAGTTGGA AAAATACGAT 
GGTGTAGATG CTGGAAAGTA TACCATTGGC CTGGGCCAGG CCAGGATGGG CTTCTGCACG 
GATCGCGAAG ACATCAACTC TCTCTGCCTG ACTGTGGTTC AGAAACTGAT GGAGAGAAAT 
AGCCTTTCCT ATGACTGCAT TGGGCGGCTG GAAGTCGGGA CAGAGACAAT CATCGACAAA 
TCAAAATCCG TGAAGTCTAA TTTGATGCAG CTGTTTGAGG AGTCTGGGAA TACAGATATA 
GAAGGAATAG ATACAACTAA TGCATGCTAT GGGGGCACAG CCGCAGTCTT CAATGCTGTG 
AACTGGATCG AATCCAGCTC TTGGGATGGA CGATACGCTT TGGTAGTTGC AGGAGACATC 
GCTATATATG CCTCAGGAAA CGCCAGGCCT ACAGGTGGAG TTGGAGCTGT GGCTCTGCTA 
ATTGGGCCAA ATGCTCCTGT AATTTTTGAC CGAGGGCTTC GTGGGACACA CATGCAGCAT 
GCCTACGACT TTTACAAGCC TGACATGCTC TCTGAATACC CTGTGGTAGA TGGAAAACTC 
TCCATACAGT GCTACCTCAG CGCATTGGAC CGCTGCTATT CTGTCTACCG CAAAAAGATC 
CGGGCCCAGT GGCAGAAAGA GGGAAAGGAT AAAGATTTTA CCCTGAATGA TTTTGGCTTC 
ATGATCTTTC ACTCGCCATA CTGTAAACTG GTGCAGAAAT CTCTAGCTAG GATGTTCCTG 
AATGACTTTC TTAACGATCA AAACAGAGAC AAAAACAGTA TTTACAGTGG GCTGGAAGCC 
TTTGGGGATG TGAAATTAGA AGATACTTAC TTCGACAGAG ATGTGGAAAA GGCATTTATG 
AAGGCTAGTG CTGAGCTATT CAACCAGAAA ACAAAGGCAT CTTTGCTTGT ATCGAATCAA 
AATGGAAACA TGTACACATC CTCTGTATAC GGTTCCCTTG CTTCTGTTCT GGCACAGTAC 
TCACCTCAAC AGTTGGCCGG GAAGAGGATT GGAGTGTTCT CTTACGGTTC TGGCTTGGCT 
GCCACACTCT ACTCCCTTAA AGTCACACAA GATGCCACAC CAGGATCTGC TCTTGACAAA 
ATAACAGCAA GTTTATGTGA CCTTAAGTCA AGGCTTGACT CAAGAACGTG TGTGGCACCA 
GACGTCTTTG CTGAAAACAT GAAGCTCAGA GAGGACACAC ATCACTTAGC CAACTATATT 
CCCCAGTGTT CAATAGATTC ACTCTTCGAA GGAACATGGT ATCTAGTCAG AGTGGATGAA 
AAGCACAGAA GAACTTACGC CCGGCGTCCC TCCACAAATG ACCACAGTTT GGATGAAGGA 
GTGGGACTTG TGCATTCAAA CACAGCTACA GAGCATATTC CAAGCCCGGC TAAGAAAGTG 
CCAAGACTTC CTGCGACCTC GGGCGAACCT GAGTCGGCTG TCATCAGTAA CGGGGAGCAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006232021.1
CDS	261..1823
Translation	MPGSLPLNAEACWPKDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQARMGFCTDREDINSLCLTVVQKLMERNSLSYDCIGRLEVGTETIIDKSKSVKSNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAIYASGNARPTGGVGAVALLIGPNAPVIFDRGLRGTHMQHAYDFYKPDMLSEYPVVDGKLSIQCYLSALDRCYSVYRKKIRAQWQKEGKDKDFTLNDFGFMIFHSPYCKLVQKSLARMFLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRDVEKAFMKASAELFNQKTKASLLVSNQNGNMYTSSVYGSLASVLAQYSPQQLAGKRIGVFSYGSGLAATLYSLKVTQDATPGSALDKITASLCDLKSRLDSRTCVAPDVFAENMKLREDTHHLANYIPQCSIDSLFEGTWYLVRVDEKHRRTYARRPSTNDHSLDEGVGLVHSNTATEHIPSPAKKVPRLPATSGEPESAVISNGEH

Target ORF information:

RefSeq Version	XM_006231959.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus 3-hydroxy-3-methylglutaryl-CoA synthase 1 (Hmgcs1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006231959.2

ORF Insert Sequence:

ATGCCTGGGT CACTTCCTTT GAATGCAGAG GCTTGCTGGC CAAAAGATGT GGGAATCGTT 
GCCCTTGAAA TCTACTTTCC TTCTCAGTAT GTTGATCAAG CTGAGTTGGA AAAATACGAT 
GGTGTAGATG CTGGAAAGTA TACCATTGGC CTGGGCCAGG CCAGGATGGG CTTCTGCACG 
GATCGCGAAG ACATCAACTC TCTCTGCCTG ACTGTGGTTC AGAAACTGAT GGAGAGAAAT 
AGCCTTTCCT ATGACTGCAT TGGGCGGCTG GAAGTCGGGA CAGAGACAAT CATCGACAAA 
TCAAAATCCG TGAAGTCTAA TTTGATGCAG CTGTTTGAGG AGTCTGGGAA TACAGATATA 
GAAGGAATAG ATACAACTAA TGCATGCTAT GGGGGCACAG CCGCAGTCTT CAATGCTGTG 
AACTGGATCG AATCCAGCTC TTGGGATGGA CGATACGCTT TGGTAGTTGC AGGAGACATC 
GCTATATATG CCTCAGGAAA CGCCAGGCCT ACAGGTGGAG TTGGAGCTGT GGCTCTGCTA 
ATTGGGCCAA ATGCTCCTGT AATTTTTGAC CGAGGGCTTC GTGGGACACA CATGCAGCAT 
GCCTACGACT TTTACAAGCC TGACATGCTC TCTGAATACC CTGTGGTAGA TGGAAAACTC 
TCCATACAGT GCTACCTCAG CGCATTGGAC CGCTGCTATT CTGTCTACCG CAAAAAGATC 
CGGGCCCAGT GGCAGAAAGA GGGAAAGGAT AAAGATTTTA CCCTGAATGA TTTTGGCTTC 
ATGATCTTTC ACTCGCCATA CTGTAAACTG GTGCAGAAAT CTCTAGCTAG GATGTTCCTG 
AATGACTTTC TTAACGATCA AAACAGAGAC AAAAACAGTA TTTACAGTGG GCTGGAAGCC 
TTTGGGGATG TGAAATTAGA AGATACTTAC TTCGACAGAG ATGTGGAAAA GGCATTTATG 
AAGGCTAGTG CTGAGCTATT CAACCAGAAA ACAAAGGCAT CTTTGCTTGT ATCGAATCAA 
AATGGAAACA TGTACACATC CTCTGTATAC GGTTCCCTTG CTTCTGTTCT GGCACAGTAC 
TCACCTCAAC AGTTGGCCGG GAAGAGGATT GGAGTGTTCT CTTACGGTTC TGGCTTGGCT 
GCCACACTCT ACTCCCTTAA AGTCACACAA GATGCCACAC CAGGATCTGC TCTTGACAAA 
ATAACAGCAA GTTTATGTGA CCTTAAGTCA AGGCTTGACT CAAGAACGTG TGTGGCACCA 
GACGTCTTTG CTGAAAACAT GAAGCTCAGA GAGGACACAC ATCACTTAGC CAACTATATT 
CCCCAGTGTT CAATAGATTC ACTCTTCGAA GGAACATGGT ATCTAGTCAG AGTGGATGAA 
AAGCACAGAA GAACTTACGC CCGGCGTCCC TCCACAAATG ACCACAGTTT GGATGAAGGA 
GTGGGACTTG TGCATTCAAA CACAGCTACA GAGCATATTC CAAGCCCGGC TAAGAAAGTG 
CCAAGACTTC CTGCGACCTC GGGCGAACCT GAGTCGGCTG TCATCAGTAA CGGGGAGCAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

HMG-CoA synthase isoenzymes 1 and 2 localize to satellite glial cells in dorsal root ganglia and are differentially regulated by peripheral nerve injury.
Brain research165262-70(2016 12)
Wang F,Xiang H,Fischer G,Liu Z,Dupont MJ,Hogan QH,Yu H

Proteomic profiling of proteins in rat spinal cord induced by contusion injury.
Neurochemistry international56(8)971-83(2010 Jul)
Yan X,Liu J,Luo Z,Ding Q,Mao X,Yan M,Yang S,Hu X,Huang J,Luo Z

Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design.
Journal of molecular biology398(4)497-506(2010 May)
Shafqat N,Turnbull A,Zschocke J,Oppermann U,Yue WW

Actein activates stress- and statin-associated responses and is bioavailable in Sprague-Dawley rats.
Fundamental & clinical pharmacology23(3)311-21(2009 Jun)
Einbond LS,Soffritti M,Esposti DD,Park T,Cruz E,Su T,Wu HA,Wang X,Zhang YJ,Ham J,Goldberg IJ,Kronenberg F,Vladimirova A

FSH and FOXO1 regulate genes in the sterol/steroid and lipid biosynthetic pathways in granulosa cells.
Molecular endocrinology (Baltimore, Md.)23(5)649-61(2009 May)
Liu Z,Rudd MD,Hernandez-Gonzalez I,Gonzalez-Robayna I,Fan HY,Zeleznik AJ,Richards JS

REQUEST A QUOTE

EMAIL

gene@genscript.com

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

Hmgcs1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

News & Blogs

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM