Smc3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Smc3
Entrez Gene ID	29486
Full Name	structural maintenance of chromosomes 3
Synonyms	Cspg6,SMC-3,bamacan
General protein information	Preferred Names structural maintenance of chromosomes 3 Names structural maintenance of chromosomes protein 3 SMC protein 3 basement membrane chondroitin sulfate proteoglycan basement membrane-associated chondroitin proteoglycan chondroitin sulfate proteoglycan 6 chromosome segregation protein SmcD structural maintenace of chromosomes 3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q55
Summary	core protein of a chondroitin sulfate proteoglycan that is a component of basement membranes [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031583.2	NP_113771.2	structural maintenance of chromosomes protein 3

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	SMC3	XP_002805863.1
Mus musculus (house mouse)	Smc3	NP_031816.2
Rattus norvegicus (Norway rat)	Smc3	NP_113771.2
Canis lupus familiaris (dog)	SMC3	XP_851818.2
Eremothecium gossypii	AGOS_AAL182W	NP_982360.1
Homo sapiens (human)	SMC3	NP_005436.1
Pan troglodytes (chimpanzee)	SMC3	XP_508031.3
Bos taurus (cattle)	SMC3	NP_776720.1
Saccharomyces cerevisiae (baker's yeast)	SMC3	NP_012461.1
Oryza sativa (rice)	Os02g0133300	NP_001045803.1
Schizosaccharomyces pombe (fission yeast)	psm3	NP_593260.1
Oryza sativa (rice)	Os02g0133400	NP_001172788.1
Gallus gallus (chicken)	SMC3	NP_989848.1
Drosophila melanogaster (fruit fly)	Cap	NP_523374.2
Caenorhabditis elegans (roundworm)	smc-3	NP_001255118.1
Arabidopsis thaliana (thale cress)	TTN7	NP_180285.4
Xenopus tropicalis (tropical clawed frog)	smc3	XP_002939544.2
Kluyveromyces lactis	KLLA0A00286g	XP_451012.2
Magnaporthe oryzae (rice blast fungus)	MGG_04988	XP_003712488.1
Danio rerio (zebrafish)	smc3	NP_999854.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006388	XP_316422.3

Gene Ontology
Bibliography

Related articles in PubMed

Meiotic cohesin complexes are essential for the formation of the axial element in mice.
Llano E, Herrán Y, García-Tuñón I, Gutiérrez-Caballero C, de Álava E, Barbero JL, Schimenti J, de Rooij DG, Sánchez-Martín M, Pendás AM
The Journal of cell biology197(7)877-85(2012 Jun)

In vitro loading of human cohesin on DNA by the human Scc2-Scc4 loader complex.
Bermudez VP, Farina A, Higashi TL, Du F, Tappin I, Takahashi TS, Hurwitz J
Proceedings of the National Academy of Sciences of the United States of America109(24)9366-71(2012 Jun)

A unique role of cohesin-SA1 in gene regulation and development.
Remeseiro S, Cuadrado A, Gómez-López G, Pisano DG, Losada A
The EMBO journal31(9)2090-102(2012 May)

The cohesin subunit RAD21L functions in meiotic synapsis and exhibits sexual dimorphism in fertility.
Herrán Y, Gutiérrez-Caballero C, Sánchez-Martín M, Hernández T, Viera A, Barbero JL, de Álava E, de Rooij DG, Suja JÁ, Llano E, Pendás AM
The EMBO journal30(15)3091-105(2011 Jul)

Meiosis in mice without a synaptonemal complex.
Kouznetsova A, Benavente R, Pastink A, Höög C
PloS one6(12)e28255(2011)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Smc3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Smc3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa08164	NM_031583.2 Latest version!	Rattus norvegicus structural maintenance of chromosomes 3 (Smc3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Smc3 ( NM_031583.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_113771.2 Rattus norvegicus structural maintenance of chromosomes 3 (Smc3), mRNA.

Price & Availability↑

CloneID	ORa08164
Clone ID Related Accession (Same CDS sequence)	NM_031583.2
Accession Version	NM_031583.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3654bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550332800000
Organism	Rattus norvegicus(Norway rat)
Product	structural maintenance of chromosomes protein 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BE109731.1, EV773232.1, BF396983.1, EV776219.1, CA511001.1, BP486487.1, BP499171.1, CO395251.1 and CA509998.1. On Oct 20, 2007 this sequence version replaced NM_031583.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTACATCA AGCAGGTGAT TATCCAGGGC TTCCGAAGTT ACCGAGATCA AACAATTGTA 
GATCCCTTCA GTTCAAAACA TAATGTTATT GTGGGCAGAA ATGGATCTGG AAAAAGCAAC 
TTTTTTTATG CAATCCAGTT TGTTCTCAGT GATGAATTTA GTCATCTTCG TCCAGAGCAG 
CGATTGGCTT TGTTGCACGA GGGTACAGGT CCTCGTGTTA TTTCTGCTTT TGTGGAAATC 
ATTTTTGACA ATTCAGACAA CCGGTTACCA ATTGATAAAG AGGAAGTTTC GCTTCGAAGA 
GTTATTGGTG CCAAAAAAGA TCAGTATTTC CTAGATAAGA AGATGGTCAC GAAAAATGAT 
GTGATGAATC TCCTTGAAAG TGCTGGGTTT TCGAGAAGTA ATCCTTATTA CATTGTTAAA 
CAAGGAAAGA TCAACCAAAT GGCAACAGCA CCGGATTCTC AGAGATTAAA GCTGTTGAGA 
GAAGTAGCTG GCACTCGAGT GTATGACGAG CGCAAAGAGG AAAGCATCTC CCTGATGAAA 
GAAACAGAGG GCAAACGGGA AAAGATCAAT GAGTTGTTAA AATACATTGA AGAGCGATTA 
CATACTCTAG AGGAGGAGAA GGAGGAACTG GCCCAGTATC AGAAGTGGGA TAAAATGAGG 
CGTGCCCTGG AGTACACCAT CTACAACCAG GAGCTCAACG AGACTCGCGC CAAGCTTGAT 
GAGCTTTCTG CTAAGCGAGA AACAAGCGGA GAGAAATCCA GACAATTAAG AGATGCCCAG 
CAGGATGCAA GAGATAAAAT GGAGGATATT GAGCGCCAAG TTAGAGAACT GAAAACAAAA 
ATTTCAGCCA TGAAAGAAGA AAAAGAACAG CTCAGTGCGG AGAGACAAGA GCAGATTAAG 
CAAAGGACCA AGCTGGAGCT TAAAGCCAAG GACTTACAGG ATGAGCTGGC AGGGAACAGT 
GAGCAGCGGA AACGTTTATT AAAAGAAAGA CAGAAGCTGC TTGAAAAAAT AGAAGAAAAG 
CAGAAAGAAC TGGCAGAAAC AGAACCGAAA TTCAACAGCG TAAAGGAAAA AGAAGAGCGA 
GGAATTGCTA GATTGGCTCA AGCTACACAG GAAAGAACTG ATCTTTATGC AAAGCAGGGT 
CGAGGAAGCC AGTTTACATC AAAAGAAGAA AGAGATAAGT GGATTAAGAA GGAACTGAAG 
TCTTTAGATC AGGCTATTAA TGATAAGAAA AGACAGATTG CTGCTATACA CAAGGATTTG 
GAGGATACCG AGGCCAATAA AGAGAAAAAT CTGGAGCAAT ATAATAAACT GGATCAGGAT 
CTCAATGAAG TCAAAGCTCG AGTTGAAGAA CTGGACAGAA AATATTATGA AGTGAAAAAT 
AAGAAAGATG AACTACAAAG TGAAAGAAAT TACTTGTGGA GAGAGGAGAA TGCAGAACAG 
CAAGCACTTG CCGCTAAGAG AGAAGACCTT GAGAAGAAGC AGCAGCTTCT TAGAGCGGCA 
ACAGGAAAGG CCATTTTAAA TGGAATCGAC AGCATTAACA AAGTGTTAGA CCATTTCCGG 
CGGAAGGGTA TAAACCAGCA TGTGCAAAAT GGCTACCATG GCATCGTGAT GAATAACTTT 
GAGTGCGAAC CAGCTTTCTA TACTTGTGTG GAAGTCACTG CCGGTAACAG GTTATTCTAT 
CACATTGTCG ATTCAGATGA AGTCAGCACG AAGATCTTAA TGGAGTTCAA TAAAATGAAT 
CTTCCTGGAG AGGTGACTTT CCTGCCTCTT AACAAGTTAG ATGTGAGGGA CACTGCCTAT 
CCTGAAACTA ACGATGCTAT TCCTATGATC AGTAAGCTGA GGTACAATCC CAGATTCGAC 
AAAGCTTTCA AACATGTGTT TGGAAAGACA CTCATCTGTC GGAGCATGGA GGTTTCCACT 
CAGCTAGCTC GTGCCTTCAC TATGGACTGC ATTACTCTGG AAGGTGATCA AGTCAGCCAT 
CGAGGTGCTC TGACTGGAGG CTATTACGAC ACAAGAAAGT CTCGCCTTGA GTTACAGAAG 
GATGTTAGGA AAGCAGAGGA GGAGCTGGGT GAGCTCGAAG CTAAGCTCAA TGAAAACCTG 
CGCAGAAACA TTGAAAGGAT TAATAATGAA ATTGATCAAT TGATGAACCA AATGCAGCAG 
ATAGAGACCC AACAGAGAAA ATTTAAAGCA TCCAGAGATA GCATCTTATC AGAGATGAAG 
ATGCTAAAAG AGAAGAGACA GCAGTCAGAA AAGACCTTCA TGCCAAAGCA ACGCAGTTTG 
CAGAGTCTGG AGGCCAGTCT GCACGCTATG GAGTCGACCA GAGAGTCGCT GAAGGCAGAG 
CTAGGGACAG ATTTGCTCTC TCAGCTCAGC CTGGAAGACC AGAAAAGAGT CGACGCACTG 
AATGACGAGA TCCGGCAGCT TCAGCAGGAA AACAGACAGC TGCTGAATGA AAGAATTAAA 
CTAGAAGGCA TTATTACTCG AGTAGAGACT TACCTCAATG AGAATCTGAG GAAACGTCTG 
GACCAAGTAG AGCAGGAACT TAATGAACTG AGAGAGACAG AAGGTGGCAC TGTTCTTACT 
GCCACCACGT CAGAACTTGA AGCTATTAAT AAAAGAGTGA AAGATACTAT GGCAAGATCA 
GAAGATTTGG ATAATTCCAT TGACAAAACA GAAGCTGGAA TTAAAGAGCT CCAGAAAAGC 
ATGGAGCGCT GGAAGAACAT GGAGAAGGAG CACATGGATG CCATAAATCA CGACACTAAA 
GAGCTGGAGA AGATGACCAA CCGACAGGGC ATGCTGTTGA AGAAGAAAGA GGAGTGCATG 
AAGAAGATCC GAGAGCTGGG GTCCCTTCCC CAGGAAGCAT TTGAAAAGTA CCAGACACTG 
AGCCTGAAGC AGTTGTTTCG GAAACTTGAG CAGTGCAACA CAGAGTTGAA GAAGTACAGC 
CATGTCAACA AGAAGGCTCT GGACCAGTTT GTGAATTTCT CTGAGCAGAA GGAGAAACTG 
ATAAAGCGAC AGGAAGAATT GGACAGGGGC TACAAGTCAA TCATGGAGTT GATGAATGTA 
CTCGAACTTA GAAAATATGA AGCTATCCAG TTAACCTTCA AACAGGTATC TAAGAACTTT 
AGTGAAGTTT TCCAGAAGTT GGTACCTGGG GGAAAAGCGA CCTTGGTGAT GAAGAAAGGA 
GACGTGGAGG GCAGCCAGTC TCAGGACGAA GGAGAGGGGA GCGGCGAGAG CGAGAGGGGC 
TCTGGGTCAC AAAGCAGCGT TCCATCAGTT GACCAGTTCA CAGGAGTCGG GATCAGGGTA 
TCATTTACAG GAAAGCAAGG CGAGATGAGA GAAATGCAGC AGCTTTCAGG AGGGCAGAAG 
TCTCTGGTAG CCCTTGCTCT CATTTTTGCC ATTCAGAAGT GTGACCCTGC TCCTTTCTAC 
CTGTTTGATG AGATCGACCA AGCTTTGGAT GCTCAGCACA GAAAAGCTGT GTCAGATATG 
ATTATGGAAC TAGCTGTACA CGCCCAGTTT ATCACTACCA CTTTTAGGCC TGAACTGCTT 
GAGTCTGCTG ATAAATTCTA CGGTGTAAAG TTCAGAAATA AGGTTAGTCA CATCGACGTG 
ATCACAGCAG AGATGGCCAA AGACTTTGTA GAAGACGATA CCACGCATGG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113771.2
CDS	123..3776
Translation	MYIKQVIIQGFRSYRDQTIVDPFSSKHNVIVGRNGSGKSNFFYAIQFVLSDEFSHLRPEQRLALLHEGTGPRVISAFVEIIFDNSDNRLPIDKEEVSLRRVIGAKKDQYFLDKKMVTKNDVMNLLESAGFSRSNPYYIVKQGKINQMATAPDSQRLKLLREVAGTRVYDERKEESISLMKETEGKREKINELLKYIEERLHTLEEEKEELAQYQKWDKMRRALEYTIYNQELNETRAKLDELSAKRETSGEKSRQLRDAQQDARDKMEDIERQVRELKTKISAMKEEKEQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKERQKLLEKIEEKQKELAETEPKFNSVKEKEERGIARLAQATQERTDLYAKQGRGSQFTSKEERDKWIKKELKSLDQAINDKKRQIAAIHKDLEDTEANKEKNLEQYNKLDQDLNEVKARVEELDRKYYEVKNKKDELQSERNYLWREENAEQQALAAKREDLEKKQQLLRAATGKAILNGIDSINKVLDHFRRKGINQHVQNGYHGIVMNNFECEPAFYTCVEVTAGNRLFYHIVDSDEVSTKILMEFNKMNLPGEVTFLPLNKLDVRDTAYPETNDAIPMISKLRYNPRFDKAFKHVFGKTLICRSMEVSTQLARAFTMDCITLEGDQVSHRGALTGGYYDTRKSRLELQKDVRKAEEELGELEAKLNENLRRNIERINNEIDQLMNQMQQIETQQRKFKASRDSILSEMKMLKEKRQQSEKTFMPKQRSLQSLEASLHAMESTRESLKAELGTDLLSQLSLEDQKRVDALNDEIRQLQQENRQLLNERIKLEGIITRVETYLNENLRKRLDQVEQELNELRETEGGTVLTATTSELEAINKRVKDTMARSEDLDNSIDKTEAGIKELQKSMERWKNMEKEHMDAINHDTKELEKMTNRQGMLLKKKEECMKKIRELGSLPQEAFEKYQTLSLKQLFRKLEQCNTELKKYSHVNKKALDQFVNFSEQKEKLIKRQEELDRGYKSIMELMNVLELRKYEAIQLTFKQVSKNFSEVFQKLVPGGKATLVMKKGDVEGSQSQDEGEGSGESERGSGSQSSVPSVDQFTGVGIRVSFTGKQGEMREMQQLSGGQKSLVALALIFAIQKCDPAPFYLFDEIDQALDAQHRKAVSDMIMELAVHAQFITTTFRPELLESADKFYGVKFRNKVSHIDVITAEMAKDFVEDDTTHG

Target ORF information:

RefSeq Version	NM_031583.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus structural maintenance of chromosomes 3 (Smc3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031583.2

ORF Insert Sequence:

ATGTACATCA AGCAGGTGAT TATCCAGGGC TTCCGAAGTT ACCGAGATCA AACAATTGTA 
GATCCCTTCA GTTCAAAACA TAATGTTATT GTGGGCAGAA ATGGATCTGG AAAAAGCAAC 
TTTTTTTATG CAATCCAGTT TGTTCTCAGT GATGAATTTA GTCATCTTCG TCCAGAGCAG 
CGATTGGCTT TGTTGCACGA GGGTACAGGT CCTCGTGTTA TTTCTGCTTT TGTGGAAATC 
ATTTTTGACA ATTCAGACAA CCGGTTACCA ATTGATAAAG AGGAAGTTTC GCTTCGAAGA 
GTTATTGGTG CCAAAAAAGA TCAGTATTTC CTAGATAAGA AGATGGTCAC GAAAAATGAT 
GTGATGAATC TCCTTGAAAG TGCTGGGTTT TCGAGAAGTA ATCCTTATTA CATTGTTAAA 
CAAGGAAAGA TCAACCAAAT GGCAACAGCA CCGGATTCTC AGAGATTAAA GCTGTTGAGA 
GAAGTAGCTG GCACTCGAGT GTATGACGAG CGCAAAGAGG AAAGCATCTC CCTGATGAAA 
GAAACAGAGG GCAAACGGGA AAAGATCAAT GAGTTGTTAA AATACATTGA AGAGCGATTA 
CATACTCTAG AGGAGGAGAA GGAGGAACTG GCCCAGTATC AGAAGTGGGA TAAAATGAGG 
CGTGCCCTGG AGTACACCAT CTACAACCAG GAGCTCAACG AGACTCGCGC CAAGCTTGAT 
GAGCTTTCTG CTAAGCGAGA AACAAGCGGA GAGAAATCCA GACAATTAAG AGATGCCCAG 
CAGGATGCAA GAGATAAAAT GGAGGATATT GAGCGCCAAG TTAGAGAACT GAAAACAAAA 
ATTTCAGCCA TGAAAGAAGA AAAAGAACAG CTCAGTGCGG AGAGACAAGA GCAGATTAAG 
CAAAGGACCA AGCTGGAGCT TAAAGCCAAG GACTTACAGG ATGAGCTGGC AGGGAACAGT 
GAGCAGCGGA AACGTTTATT AAAAGAAAGA CAGAAGCTGC TTGAAAAAAT AGAAGAAAAG 
CAGAAAGAAC TGGCAGAAAC AGAACCGAAA TTCAACAGCG TAAAGGAAAA AGAAGAGCGA 
GGAATTGCTA GATTGGCTCA AGCTACACAG GAAAGAACTG ATCTTTATGC AAAGCAGGGT 
CGAGGAAGCC AGTTTACATC AAAAGAAGAA AGAGATAAGT GGATTAAGAA GGAACTGAAG 
TCTTTAGATC AGGCTATTAA TGATAAGAAA AGACAGATTG CTGCTATACA CAAGGATTTG 
GAGGATACCG AGGCCAATAA AGAGAAAAAT CTGGAGCAAT ATAATAAACT GGATCAGGAT 
CTCAATGAAG TCAAAGCTCG AGTTGAAGAA CTGGACAGAA AATATTATGA AGTGAAAAAT 
AAGAAAGATG AACTACAAAG TGAAAGAAAT TACTTGTGGA GAGAGGAGAA TGCAGAACAG 
CAAGCACTTG CCGCTAAGAG AGAAGACCTT GAGAAGAAGC AGCAGCTTCT TAGAGCGGCA 
ACAGGAAAGG CCATTTTAAA TGGAATCGAC AGCATTAACA AAGTGTTAGA CCATTTCCGG 
CGGAAGGGTA TAAACCAGCA TGTGCAAAAT GGCTACCATG GCATCGTGAT GAATAACTTT 
GAGTGCGAAC CAGCTTTCTA TACTTGTGTG GAAGTCACTG CCGGTAACAG GTTATTCTAT 
CACATTGTCG ATTCAGATGA AGTCAGCACG AAGATCTTAA TGGAGTTCAA TAAAATGAAT 
CTTCCTGGAG AGGTGACTTT CCTGCCTCTT AACAAGTTAG ATGTGAGGGA CACTGCCTAT 
CCTGAAACTA ACGATGCTAT TCCTATGATC AGTAAGCTGA GGTACAATCC CAGATTCGAC 
AAAGCTTTCA AACATGTGTT TGGAAAGACA CTCATCTGTC GGAGCATGGA GGTTTCCACT 
CAGCTAGCTC GTGCCTTCAC TATGGACTGC ATTACTCTGG AAGGTGATCA AGTCAGCCAT 
CGAGGTGCTC TGACTGGAGG CTATTACGAC ACAAGAAAGT CTCGCCTTGA GTTACAGAAG 
GATGTTAGGA AAGCAGAGGA GGAGCTGGGT GAGCTCGAAG CTAAGCTCAA TGAAAACCTG 
CGCAGAAACA TTGAAAGGAT TAATAATGAA ATTGATCAAT TGATGAACCA AATGCAGCAG 
ATAGAGACCC AACAGAGAAA ATTTAAAGCA TCCAGAGATA GCATCTTATC AGAGATGAAG 
ATGCTAAAAG AGAAGAGACA GCAGTCAGAA AAGACCTTCA TGCCAAAGCA ACGCAGTTTG 
CAGAGTCTGG AGGCCAGTCT GCACGCTATG GAGTCGACCA GAGAGTCGCT GAAGGCAGAG 
CTAGGGACAG ATTTGCTCTC TCAGCTCAGC CTGGAAGACC AGAAAAGAGT CGACGCACTG 
AATGACGAGA TCCGGCAGCT TCAGCAGGAA AACAGACAGC TGCTGAATGA AAGAATTAAA 
CTAGAAGGCA TTATTACTCG AGTAGAGACT TACCTCAATG AGAATCTGAG GAAACGTCTG 
GACCAAGTAG AGCAGGAACT TAATGAACTG AGAGAGACAG AAGGTGGCAC TGTTCTTACT 
GCCACCACGT CAGAACTTGA AGCTATTAAT AAAAGAGTGA AAGATACTAT GGCAAGATCA 
GAAGATTTGG ATAATTCCAT TGACAAAACA GAAGCTGGAA TTAAAGAGCT CCAGAAAAGC 
ATGGAGCGCT GGAAGAACAT GGAGAAGGAG CACATGGATG CCATAAATCA CGACACTAAA 
GAGCTGGAGA AGATGACCAA CCGACAGGGC ATGCTGTTGA AGAAGAAAGA GGAGTGCATG 
AAGAAGATCC GAGAGCTGGG GTCCCTTCCC CAGGAAGCAT TTGAAAAGTA CCAGACACTG 
AGCCTGAAGC AGTTGTTTCG GAAACTTGAG CAGTGCAACA CAGAGTTGAA GAAGTACAGC 
CATGTCAACA AGAAGGCTCT GGACCAGTTT GTGAATTTCT CTGAGCAGAA GGAGAAACTG 
ATAAAGCGAC AGGAAGAATT GGACAGGGGC TACAAGTCAA TCATGGAGTT GATGAATGTA 
CTCGAACTTA GAAAATATGA AGCTATCCAG TTAACCTTCA AACAGGTATC TAAGAACTTT 
AGTGAAGTTT TCCAGAAGTT GGTACCTGGG GGAAAAGCGA CCTTGGTGAT GAAGAAAGGA 
GACGTGGAGG GCAGCCAGTC TCAGGACGAA GGAGAGGGGA GCGGCGAGAG CGAGAGGGGC 
TCTGGGTCAC AAAGCAGCGT TCCATCAGTT GACCAGTTCA CAGGAGTCGG GATCAGGGTA 
TCATTTACAG GAAAGCAAGG CGAGATGAGA GAAATGCAGC AGCTTTCAGG AGGGCAGAAG 
TCTCTGGTAG CCCTTGCTCT CATTTTTGCC ATTCAGAAGT GTGACCCTGC TCCTTTCTAC 
CTGTTTGATG AGATCGACCA AGCTTTGGAT GCTCAGCACA GAAAAGCTGT GTCAGATATG 
ATTATGGAAC TAGCTGTACA CGCCCAGTTT ATCACTACCA CTTTTAGGCC TGAACTGCTT 
GAGTCTGCTG ATAAATTCTA CGGTGTAAAG TTCAGAAATA AGGTTAGTCA CATCGACGTG 
ATCACAGCAG AGATGGCCAA AGACTTTGTA GAAGACGATA CCACGCATGG TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Meiotic cohesin complexes are essential for the formation of the axial element in mice.
The Journal of cell biology197(7)877-85(2012 Jun)
Llano E,Herrán Y,García-Tuñón I,Gutiérrez-Caballero C,de Álava E,Barbero JL,Schimenti J,de Rooij DG,Sánchez-Martín M,Pendás AM

In vitro loading of human cohesin on DNA by the human Scc2-Scc4 loader complex.
Proceedings of the National Academy of Sciences of the United States of America109(24)9366-71(2012 Jun)
Bermudez VP,Farina A,Higashi TL,Du F,Tappin I,Takahashi TS,Hurwitz J

A unique role of cohesin-SA1 in gene regulation and development.
The EMBO journal31(9)2090-102(2012 May)
Remeseiro S,Cuadrado A,Gómez-López G,Pisano DG,Losada A

The cohesin subunit RAD21L functions in meiotic synapsis and exhibits sexual dimorphism in fertility.
The EMBO journal30(15)3091-105(2011 Jul)
Herrán Y,Gutiérrez-Caballero C,Sánchez-Martín M,Hernández T,Viera A,Barbero JL,de Álava E,de Rooij DG,Suja JÁ,Llano E,Pendás AM

Meiosis in mice without a synaptonemal complex.
PloS one6(12)e28255(2011)
Kouznetsova A,Benavente R,Pastink A,Höög C

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Smc3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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