Cbln2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cbln2
Entrez Gene ID	291388
Full Name	cerebellin 2 precursor
General protein information	Preferred Names cerebellin 2 precursor Names cerebellin-2 cerebellin 2 precursor protein cerebellin-like protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 18 Map Location: 18q13

mRNA and Protein(s)

mRNA	Protein	Name
NM_001012740.1	NP_001012758.1	cerebellin-2 precursor
XM_006255024.3	XP_006255086.1	cerebellin-2 isoform X1
XM_006255023.3	XP_006255085.1	cerebellin-2 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	CBLN2	XP_541056.4
Mus musculus (house mouse)	Cbln2	NP_766221.1
Macaca mulatta (Rhesus monkey)	CBLN2	XP_001082250.1
Rattus norvegicus (Norway rat)	Cbln2	NP_001012758.1
Gallus gallus (chicken)	CBLN2	NP_001165239.1
Xenopus tropicalis (tropical clawed frog)	cbln2	NP_001106397.1
Pan troglodytes (chimpanzee)	CBLN2	XP_523968.1
Bos taurus (cattle)	CBLN2	NP_001092389.1
Homo sapiens (human)	CBLN2	NP_872317.1

Gene Ontology
Bibliography

Related articles in PubMed

Postsynaptic δ1 glutamate receptor assembles and maintains hippocampal synapses via Cbln2 and neurexin.
Tao W, Díaz-Alonso J, Sheng N, Nicoll RA
Proceedings of the National Academy of Sciences of the United States of America115(23)E5373-E5381(2018 06)

Cbln family proteins promote synapse formation by regulating distinct neurexin signaling pathways in various brain regions.
Matsuda K, Yuzaki M
The European journal of neuroscience33(8)1447-61(2011 Apr)

Differential interactions of cerebellin precursor protein (Cbln) subtypes and neurexin variants for synapse formation of cortical neurons.
Joo JY, Lee SJ, Uemura T, Yoshida T, Yasumura M, Watanabe M, Mishina M
Biochemical and biophysical research communications406(4)627-32(2011 Mar)

Characterization of a transneuronal cytokine family Cbln--regulation of secretion by heteromeric assembly.
Iijima T, Miura E, Matsuda K, Kamekawa Y, Watanabe M, Yuzaki M
The European journal of neuroscience25(4)1049-57(2007 Feb)

Cerebellin in the rat adrenal gland: gene expression and effects of CER and [des-Ser1]CER on the secretion and growth of cultured adrenocortical cells.
Rucinski M, Albertin G, Spinazzi R, Ziolkowska A, Nussdorfer GG, Malendowicz LK
International journal of molecular medicine15(3)411-5(2005 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cbln2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cbln2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa02991	NM_001012740.1 Latest version!	Rattus norvegicus cerebellin 2 precursor (Cbln2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
ORa02991	XM_006255024.3 Latest version!	Rattus norvegicus cerebellin 2 precursor (Cbln2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
ORa02991	XM_006255023.3 Latest version!	Rattus norvegicus cerebellin 2 precursor (Cbln2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

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5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cbln2 ( NM_001012740.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001012758.1 Rattus norvegicus cerebellin 2 precursor (Cbln2), mRNA.

Price & Availability↑

CloneID	ORa02991
Clone ID Related Accession (Same CDS sequence)	NM_001012740.1 , XM_006255024.3 , XM_006255023.3
Accession Version	NM_001012740.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569168000000
Organism	Rattus norvegicus(Norway rat)
Product	cerebellin-2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC091341.1. On Apr 20, 2005 this sequence version replaced XM_225659.3. ##Evidence-Data-START## Transcript exon combination :: BC091341.1, CO393408.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCCCGCTC CTGGCCGGGG CCCCAGAGGG CCGCTGCTGA GCATGCCCGG GCGCCGGGGG 
GCGCTGCGTG AGCCGGCCGA CTTTGGCTCC AGCCTGGGGG CGGCGCTGGC CCTGCTGTTG 
CTGCTGCTGC CCGCCTGCTG CCCGGTAAAG GCTCAGAACG ACACGGAGCC CATCGTGCTA 
GAGGGCAAGT GCCTGGTAGT GTGCGATTCC AGTCCATCGG GGGATGGCGC TGTCACTTCT 
TCCCTGGGCA TATCTGTGCG CTCAGGCAGT GCCAAGGTGG CCTTCTCCGC TACTCGGAGC 
ACCAACCACG AGCCTTCAGA GATGAGCAAC CGTACCATGA CCATCTACTT CGACCAGGTT 
TTAGTAAACA TTGGCAACCA CTTTGACCTT GCCTCGAGTA TATTTGTAGC ACCAAGGAAA 
GGAATTTATA GCTTCAGCTT CCACGTGGTC AAAGTGTACA ACAGACAAAC TATCCAGGTC 
AGTTTAATGC AGAACGGCTA CCCGGTGATC TCTGCCTTTG CTGGAGACCA GGATGTTACC 
AGGGAAGCAG CCAGCAATGG TGTTCTGCTT CTCATGGAAA GAGAAGACAA AGTTCATCTC 
AAACTGGAGA GAGGCAACCT CATGGGAGGC TGGAAATACT CCACATTCTC GGGCTTCTTG 
GTTTTTCCTC TATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001012758.1
CDS	180..854
Translation	MPAPGRGPRGPLLSMPGRRGALREPADFGSSLGAALALLLLLLPACCPVKAQNDTEPIVLEGKCLVVCDSSPSGDGAVTSSLGISVRSGSAKVAFSATRSTNHEPSEMSNRTMTIYFDQVLVNIGNHFDLASSIFVAPRKGIYSFSFHVVKVYNRQTIQVSLMQNGYPVISAFAGDQDVTREAASNGVLLLMEREDKVHLKLERGNLMGGWKYSTFSGFLVFPL

Target ORF information:

RefSeq Version	NM_001012740.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cerebellin 2 precursor (Cbln2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001012740.1

ORF Insert Sequence:

ATGCCCGCTC CTGGCCGGGG CCCCAGAGGG CCGCTGCTGA GCATGCCCGG GCGCCGGGGG 
GCGCTGCGTG AGCCGGCCGA CTTTGGCTCC AGCCTGGGGG CGGCGCTGGC CCTGCTGTTG 
CTGCTGCTGC CCGCCTGCTG CCCGGTAAAG GCTCAGAACG ACACGGAGCC CATCGTGCTA 
GAGGGCAAGT GCCTGGTAGT GTGCGATTCC AGTCCATCGG GGGATGGCGC TGTCACTTCT 
TCCCTGGGCA TATCTGTGCG CTCAGGCAGT GCCAAGGTGG CCTTCTCCGC TACTCGGAGC 
ACCAACCACG AGCCTTCAGA GATGAGCAAC CGTACCATGA CCATCTACTT CGACCAGGTT 
TTAGTAAACA TTGGCAACCA CTTTGACCTT GCCTCGAGTA TATTTGTAGC ACCAAGGAAA 
GGAATTTATA GCTTCAGCTT CCACGTGGTC AAAGTGTACA ACAGACAAAC TATCCAGGTC 
AGTTTAATGC AGAACGGCTA CCCGGTGATC TCTGCCTTTG CTGGAGACCA GGATGTTACC 
AGGGAAGCAG CCAGCAATGG TGTTCTGCTT CTCATGGAAA GAGAAGACAA AGTTCATCTC 
AAACTGGAGA GAGGCAACCT CATGGGAGGC TGGAAATACT CCACATTCTC GGGCTTCTTG 
GTTTTTCCTC TATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cbln2 ( XM_006255024.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006255086.1 Rattus norvegicus cerebellin 2 precursor (Cbln2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa02991
Clone ID Related Accession (Same CDS sequence)	NM_001012740.1 , XM_006255024.3 , XM_006255023.3
Accession Version	XM_006255024.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	cerebellin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005117.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006255024.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCGCTC CTGGCCGGGG CCCCAGAGGG CCGCTGCTGA GCATGCCCGG GCGCCGGGGG 
GCGCTGCGTG AGCCGGCCGA CTTTGGCTCC AGCCTGGGGG CGGCGCTGGC CCTGCTGTTG 
CTGCTGCTGC CCGCCTGCTG CCCGGTAAAG GCTCAGAACG ACACGGAGCC CATCGTGCTA 
GAGGGCAAGT GCCTGGTAGT GTGCGATTCC AGTCCATCGG GGGATGGCGC TGTCACTTCT 
TCCCTGGGCA TATCTGTGCG CTCAGGCAGT GCCAAGGTGG CCTTCTCCGC TACTCGGAGC 
ACCAACCACG AGCCTTCAGA GATGAGCAAC CGTACCATGA CCATCTACTT CGACCAGGTT 
TTAGTAAACA TTGGCAACCA CTTTGACCTT GCCTCGAGTA TATTTGTAGC ACCAAGGAAA 
GGAATTTATA GCTTCAGCTT CCACGTGGTC AAAGTGTACA ACAGACAAAC TATCCAGGTC 
AGTTTAATGC AGAACGGCTA CCCGGTGATC TCTGCCTTTG CTGGAGACCA GGATGTTACC 
AGGGAAGCAG CCAGCAATGG TGTTCTGCTT CTCATGGAAA GAGAAGACAA AGTTCATCTC 
AAACTGGAGA GAGGCAACCT CATGGGAGGC TGGAAATACT CCACATTCTC GGGCTTCTTG 
GTTTTTCCTC TATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006255086.1
CDS	358..1032
Translation	MPAPGRGPRGPLLSMPGRRGALREPADFGSSLGAALALLLLLLPACCPVKAQNDTEPIVLEGKCLVVCDSSPSGDGAVTSSLGISVRSGSAKVAFSATRSTNHEPSEMSNRTMTIYFDQVLVNIGNHFDLASSIFVAPRKGIYSFSFHVVKVYNRQTIQVSLMQNGYPVISAFAGDQDVTREAASNGVLLLMEREDKVHLKLERGNLMGGWKYSTFSGFLVFPL

Target ORF information:

RefSeq Version	XM_006255024.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cerebellin 2 precursor (Cbln2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006255024.3

ORF Insert Sequence:

ATGCCCGCTC CTGGCCGGGG CCCCAGAGGG CCGCTGCTGA GCATGCCCGG GCGCCGGGGG 
GCGCTGCGTG AGCCGGCCGA CTTTGGCTCC AGCCTGGGGG CGGCGCTGGC CCTGCTGTTG 
CTGCTGCTGC CCGCCTGCTG CCCGGTAAAG GCTCAGAACG ACACGGAGCC CATCGTGCTA 
GAGGGCAAGT GCCTGGTAGT GTGCGATTCC AGTCCATCGG GGGATGGCGC TGTCACTTCT 
TCCCTGGGCA TATCTGTGCG CTCAGGCAGT GCCAAGGTGG CCTTCTCCGC TACTCGGAGC 
ACCAACCACG AGCCTTCAGA GATGAGCAAC CGTACCATGA CCATCTACTT CGACCAGGTT 
TTAGTAAACA TTGGCAACCA CTTTGACCTT GCCTCGAGTA TATTTGTAGC ACCAAGGAAA 
GGAATTTATA GCTTCAGCTT CCACGTGGTC AAAGTGTACA ACAGACAAAC TATCCAGGTC 
AGTTTAATGC AGAACGGCTA CCCGGTGATC TCTGCCTTTG CTGGAGACCA GGATGTTACC 
AGGGAAGCAG CCAGCAATGG TGTTCTGCTT CTCATGGAAA GAGAAGACAA AGTTCATCTC 
AAACTGGAGA GAGGCAACCT CATGGGAGGC TGGAAATACT CCACATTCTC GGGCTTCTTG 
GTTTTTCCTC TATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cbln2 ( XM_006255023.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006255085.1 Rattus norvegicus cerebellin 2 precursor (Cbln2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa02991
Clone ID Related Accession (Same CDS sequence)	NM_001012740.1 , XM_006255024.3 , XM_006255023.3
Accession Version	XM_006255023.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	cerebellin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005117.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006255023.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCGCTC CTGGCCGGGG CCCCAGAGGG CCGCTGCTGA GCATGCCCGG GCGCCGGGGG 
GCGCTGCGTG AGCCGGCCGA CTTTGGCTCC AGCCTGGGGG CGGCGCTGGC CCTGCTGTTG 
CTGCTGCTGC CCGCCTGCTG CCCGGTAAAG GCTCAGAACG ACACGGAGCC CATCGTGCTA 
GAGGGCAAGT GCCTGGTAGT GTGCGATTCC AGTCCATCGG GGGATGGCGC TGTCACTTCT 
TCCCTGGGCA TATCTGTGCG CTCAGGCAGT GCCAAGGTGG CCTTCTCCGC TACTCGGAGC 
ACCAACCACG AGCCTTCAGA GATGAGCAAC CGTACCATGA CCATCTACTT CGACCAGGTT 
TTAGTAAACA TTGGCAACCA CTTTGACCTT GCCTCGAGTA TATTTGTAGC ACCAAGGAAA 
GGAATTTATA GCTTCAGCTT CCACGTGGTC AAAGTGTACA ACAGACAAAC TATCCAGGTC 
AGTTTAATGC AGAACGGCTA CCCGGTGATC TCTGCCTTTG CTGGAGACCA GGATGTTACC 
AGGGAAGCAG CCAGCAATGG TGTTCTGCTT CTCATGGAAA GAGAAGACAA AGTTCATCTC 
AAACTGGAGA GAGGCAACCT CATGGGAGGC TGGAAATACT CCACATTCTC GGGCTTCTTG 
GTTTTTCCTC TATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006255085.1
CDS	545..1219
Translation	MPAPGRGPRGPLLSMPGRRGALREPADFGSSLGAALALLLLLLPACCPVKAQNDTEPIVLEGKCLVVCDSSPSGDGAVTSSLGISVRSGSAKVAFSATRSTNHEPSEMSNRTMTIYFDQVLVNIGNHFDLASSIFVAPRKGIYSFSFHVVKVYNRQTIQVSLMQNGYPVISAFAGDQDVTREAASNGVLLLMEREDKVHLKLERGNLMGGWKYSTFSGFLVFPL

Target ORF information:

RefSeq Version	XM_006255023.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cerebellin 2 precursor (Cbln2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006255023.3

ORF Insert Sequence:

ATGCCCGCTC CTGGCCGGGG CCCCAGAGGG CCGCTGCTGA GCATGCCCGG GCGCCGGGGG 
GCGCTGCGTG AGCCGGCCGA CTTTGGCTCC AGCCTGGGGG CGGCGCTGGC CCTGCTGTTG 
CTGCTGCTGC CCGCCTGCTG CCCGGTAAAG GCTCAGAACG ACACGGAGCC CATCGTGCTA 
GAGGGCAAGT GCCTGGTAGT GTGCGATTCC AGTCCATCGG GGGATGGCGC TGTCACTTCT 
TCCCTGGGCA TATCTGTGCG CTCAGGCAGT GCCAAGGTGG CCTTCTCCGC TACTCGGAGC 
ACCAACCACG AGCCTTCAGA GATGAGCAAC CGTACCATGA CCATCTACTT CGACCAGGTT 
TTAGTAAACA TTGGCAACCA CTTTGACCTT GCCTCGAGTA TATTTGTAGC ACCAAGGAAA 
GGAATTTATA GCTTCAGCTT CCACGTGGTC AAAGTGTACA ACAGACAAAC TATCCAGGTC 
AGTTTAATGC AGAACGGCTA CCCGGTGATC TCTGCCTTTG CTGGAGACCA GGATGTTACC 
AGGGAAGCAG CCAGCAATGG TGTTCTGCTT CTCATGGAAA GAGAAGACAA AGTTCATCTC 
AAACTGGAGA GAGGCAACCT CATGGGAGGC TGGAAATACT CCACATTCTC GGGCTTCTTG 
GTTTTTCCTC TATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Postsynaptic δ1 glutamate receptor assembles and maintains hippocampal synapses via Cbln2 and neurexin.
Proceedings of the National Academy of Sciences of the United States of America115(23)E5373-E5381(2018 06)
Tao W,Díaz-Alonso J,Sheng N,Nicoll RA

Cbln family proteins promote synapse formation by regulating distinct neurexin signaling pathways in various brain regions.
The European journal of neuroscience33(8)1447-61(2011 Apr)
Matsuda K,Yuzaki M

Differential interactions of cerebellin precursor protein (Cbln) subtypes and neurexin variants for synapse formation of cortical neurons.
Biochemical and biophysical research communications406(4)627-32(2011 Mar)
Joo JY,Lee SJ,Uemura T,Yoshida T,Yasumura M,Watanabe M,Mishina M

Characterization of a transneuronal cytokine family Cbln--regulation of secretion by heteromeric assembly.
The European journal of neuroscience25(4)1049-57(2007 Feb)
Iijima T,Miura E,Matsuda K,Kamekawa Y,Watanabe M,Yuzaki M

Cerebellin in the rat adrenal gland: gene expression and effects of CER and [des-Ser1]CER on the secretion and growth of cultured adrenocortical cells.
International journal of molecular medicine15(3)411-5(2005 Mar)
Rucinski M,Albertin G,Spinazzi R,Ziolkowska A,Nussdorfer GG,Malendowicz LK

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Cbln2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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