Coprs cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Coprs
Entrez Gene ID	290925
Full Name	coordinator of PRMT5 and differentiation stimulator
Synonyms	Copr5,RGD1565675
General protein information	Preferred Names coordinator of PRMT5 and differentiation stimulator Names coordinator of PRMT5 and differentiation stimulator cooperator of PRMT5 coordinator of PRMT5, differentiation stimulator
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 16 Map Location: 16q12.5

mRNA and Protein(s)

mRNA	Protein	Name
NM_001169121.1	NP_001162592.1	coordinator of PRMT5 and differentiation stimulator

Pathways from BioSystems

Homologies

Homo sapiens (human)	COPRS	NP_060875.2
Canis lupus familiaris (dog)	C9H17orf79	XP_005625056.1
Bos taurus (cattle)	COPRS	NP_001092364.1
Rattus norvegicus (Norway rat)	Coprs	NP_001162592.1
Pan troglodytes (chimpanzee)	C17H17orf79	XP_001174701.1
Macaca mulatta (Rhesus monkey)	LOC713293	XP_001112181.1
Mus musculus (house mouse)	Coprs	NP_079832.1

Gene Ontology
Bibliography

Related articles in PubMed

Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos.
Cui W, Dai X, Marcho C, Han Z, Zhang K, Tremblay KD, Mager J
Scientific reports637396(2016 11)

The histone- and PRMT5-associated protein COPR5 is required for myogenic differentiation.
Paul C, Sardet C, Fabbrizio E
Cell death and differentiation19(5)900-8(2012 May)

The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5.
Lacroix M, El Messaoudi S, Rodier G, Le Cam A, Sardet C, Fabbrizio E
EMBO reports9(5)452-8(2008 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Coprs gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Coprs cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06053	NM_001169121.1 Latest version!	Rattus norvegicus coordinator of PRMT5 and differentiation stimulator (Coprs), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Coprs ( NM_001169121.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001162592.1 Rattus norvegicus coordinator of PRMT5 and differentiation stimulator (Coprs), mRNA.

Price & Availability↑

CloneID	ORa06053
Clone ID Related Accession (Same CDS sequence)	NM_001169121.1
Accession Version	NM_001169121.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 522bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1555516800000
Organism	Rattus norvegicus(Norway rat)
Product	coordinator of PRMT5 and differentiation stimulator
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB614079.1. On or before Dec 16, 2009 this sequence version replaced XM_214404.4, XM_001075131.1. ##Evidence-Data-START## Transcript exon combination :: CB614079.1, FM062948.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGACCCTC AGGCAGCCAC CGGTCCGGGG CCGGGCGAGC CGAGTGCATG GGAGGCCCCC 
AGCGCGGAGG CTGGTCTTGC CACAGCTGAC CTCTCTGGTG GGGAGACAGA GACTGAGCTA 
GACGTGGACC GACTAGCCAG TGGAGCTCAG AGCATCCCTA CTGACGTTCC TACCCATGCC 
GAGGGCCCAA GTTCTGAAGA GGAAGGCTTT GCAATGGAGA AGGAAGCGGA TGGGGAACTG 
TATGCCTGGG AGCTGTCAGA AGGTCCAGCC TGCCCACCCA TGGAACAGGC TTCTGGTCTT 
TTTAACGAGG ACTGGGACTT GGAGCTGAAA GCGGACCAAG GGAATCCTTA CGATGCTGAT 
GACGTCCAAG GGAGCATTTC CCAAGAGATT AAGCCGTGGG TGTGCTGTGC ACCACAAGGA 
GATATGATGT ATGACCCCAG TTGGCACCAT CCACCCCCAC TGATACCACA TTACTCCAAG 
ATGGTCTTTG AAACAGGACA GTTTGATGAT GCAGAAGACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001162592.1
CDS	27..548
Translation	MDPQAATGPGPGEPSAWEAPSAEAGLATADLSGGETETELDVDRLASGAQSIPTDVPTHAEGPSSEEEGFAMEKEADGELYAWELSEGPACPPMEQASGLFNEDWDLELKADQGNPYDADDVQGSISQEIKPWVCCAPQGDMMYDPSWHHPPPLIPHYSKMVFETGQFDDAED

Target ORF information:

RefSeq Version	NM_001169121.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus coordinator of PRMT5 and differentiation stimulator (Coprs), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001169121.1

ORF Insert Sequence:

ATGGACCCTC AGGCAGCCAC CGGTCCGGGG CCGGGCGAGC CGAGTGCATG GGAGGCCCCC 
AGCGCGGAGG CTGGTCTTGC CACAGCTGAC CTCTCTGGTG GGGAGACAGA GACTGAGCTA 
GACGTGGACC GACTAGCCAG TGGAGCTCAG AGCATCCCTA CTGACGTTCC TACCCATGCC 
GAGGGCCCAA GTTCTGAAGA GGAAGGCTTT GCAATGGAGA AGGAAGCGGA TGGGGAACTG 
TATGCCTGGG AGCTGTCAGA AGGTCCAGCC TGCCCACCCA TGGAACAGGC TTCTGGTCTT 
TTTAACGAGG ACTGGGACTT GGAGCTGAAA GCGGACCAAG GGAATCCTTA CGATGCTGAT 
GACGTCCAAG GGAGCATTTC CCAAGAGATT AAGCCGTGGG TGTGCTGTGC ACCACAAGGA 
GATATGATGT ATGACCCCAG TTGGCACCAT CCACCCCCAC TGATACCACA TTACTCCAAG 
ATGGTCTTTG AAACAGGACA GTTTGATGAT GCAGAAGACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos.
Scientific reports637396(2016 11)
Cui W,Dai X,Marcho C,Han Z,Zhang K,Tremblay KD,Mager J

The histone- and PRMT5-associated protein COPR5 is required for myogenic differentiation.
Cell death and differentiation19(5)900-8(2012 May)
Paul C,Sardet C,Fabbrizio E

The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5.
EMBO reports9(5)452-8(2008 May)
Lacroix M,El Messaoudi S,Rodier G,Le Cam A,Sardet C,Fabbrizio E