Krt17 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Krt17
Entrez Gene ID	287702
Full Name	keratin 17
Synonyms	Ka17
General protein information	Preferred Names keratin 17 Names keratin, type I cytoskeletal 17 CK-17 K17 cytokeratin-17 keratin 17, type I type I keratin KA17
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q31

mRNA and Protein(s)

mRNA	Protein	Name
NM_212545.2	NP_997710.1	keratin, type I cytoskeletal 17

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	KRT17	XP_548100.1
Danio rerio (zebrafish)	si:dkeyp-113d7.4	NP_001107814.1
Danio rerio (zebrafish)	krt1-19d	XP_001342789.4
Macaca mulatta (Rhesus monkey)	KRT17	XP_002800509.1
Xenopus tropicalis (tropical clawed frog)	LOC100490897	XP_002939077.1
Bos taurus (cattle)	KRT17	NP_001098792.1
Danio rerio (zebrafish)	krt15	NP_998688.1
Danio rerio (zebrafish)	zgc:92533	NP_001003445.1
Danio rerio (zebrafish)	krt17	NP_001076574.1
Mus musculus (house mouse)	Krt17	NP_034793.1
Rattus norvegicus (Norway rat)	Krt17	NP_997710.1
Danio rerio (zebrafish)	wu:fb17f05	NP_001186881.1
Danio rerio (zebrafish)	cyt1l	NP_001076351.1
Danio rerio (zebrafish)	cyt1	NP_571182.1
Danio rerio (zebrafish)	zgc:92061	NP_001002383.1
Danio rerio (zebrafish)	zgc:109868	NP_001017824.1
Homo sapiens (human)	KRT17	NP_000413.1
Pan troglodytes (chimpanzee)	KRT17	NP_001138309.1

Gene Ontology
Bibliography

Related articles in PubMed

Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects.
Saunders SP, Goh CS, Brown SJ, Palmer CN, Porter RM, Cole C, Campbell LE, Gierlinski M, Barton GJ, Schneider G, Balmain A, Prescott AR, Weidinger S, Baurecht H, Kabesch M, Gieger C, Lee YA, Tavendale R, Mukhopadhyay S, Turner SW, Madhok VB, Sullivan FM, Relton C, Burn J, Meggitt S, Smith CH, Allen MA, Barker JN, Reynolds NJ, Cordell HJ, Irvine AD, McLean WH, Sandilands A, Fallon PG
The Journal of allergy and clinical immunology132(5)1121-9(2013 Nov)

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal of proteome research8(3)1304-14(2009 Mar)

The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles.
Andl T, Murchison EP, Liu F, Zhang Y, Yunta-Gonzalez M, Tobias JW, Andl CD, Seykora JT, Hannon GJ, Millar SE
Current biology : CB16(10)1041-9(2006 May)

Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion.
Tong X, Coulombe PA
Genes & development20(10)1353-64(2006 May)

A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth.
Kim S, Wong P, Coulombe PA
Nature441(7091)362-5(2006 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Krt17 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Krt17 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05742	NM_212545.2 Latest version!	Rattus norvegicus keratin 17 (Krt17), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Krt17 ( NM_212545.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_997710.1 Rattus norvegicus keratin 17 (Krt17), mRNA.

Price & Availability↑

CloneID	ORa05742
Clone ID Related Accession (Same CDS sequence)	NM_212545.2
Accession Version	NM_212545.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1302bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Rattus norvegicus(Norway rat)
Product	keratin, type I cytoskeletal 17
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC100058.1. On Aug 7, 2005 this sequence version replaced NM_212545.1. ##Evidence-Data-START## Transcript exon combination :: BC100058.1, BK004050.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689602 [ECO:0000348] ##Evidence-Data-END##

ATGACTACCA CCATCCGCCA GTTCACGTCC TCCAGCTCCA TCAAGGGCTC CTCTGGCCTG 
GGTGGCGGCT CATCTAGGAC CTCCTGCCGA CTGTCTGGCA GCCTGGGTGC AGGCTCCTGC 
AGGCTGGGGT CAGCTAGTGG CCTGGGCAGT GCTCTTGGGG GCAACAGTTA CTCCAGCTGC 
TACAGCTTTG GTACTGGCAG TGGTTATGGA GGCAACTTTG GGGGTGTTGA TGGGCTGCTG 
GCTGGAGGGG AGAAGGCCAC CATGCAGAAC CTCAACGACC GCCTGGCCTC CTACCTGGAC 
AAGGTGCGTG CCCTGGAAGA GGCCAACACC GAGCTGGAGG TGAAGATCCG AGACTGGTAC 
CAGAAGCAGG CCCCAGGGCC AGCCCGCGAC TACAGTGCTT ATTACCAGAC CATTGAGGAT 
CTGAAGAACA AGATCCTCGT GGCCACTGTG GATAATGCCA GCATCCTACT CCAGATTGAC 
AATGCCCGCT TGGCAGCTGA TGACTTCCGT ACCAAGTTTG AGACGGAGCA GGCCCTGCGC 
ATGAGTGTGG AGGCGGACAT CAATGGCCTA CGCCGGGTGC TGGATGAGCT GACCCTGGCC 
AGAGCTGACC TGGAGATGCA GATTGAGAAT CTCAAGGAGG AGCTGGCCTA CCTGAAGAAG 
AACCATGAGG AGGAGATGAA TGCTCTGAGA GGCCAGGTGG GCGGCGAAAT CAACGTGGAG 
ATGGACGCAG CCCCTGGTGT GGACCTGAGC CGCATCCTGT CAGAGATGCG GGATCAGTAC 
GAGAAGATGG CTGAGAAGAA CCGCAAGGAT GCCGAAGATT GGTTCTTCAG CAAGACTGAG 
GAGCTAAACC GCGAGGTGGC CACCAACAGC GAGCTGGTGC AGAGCGGCAA GAGCGAGATC 
TCTGAGCTCC GGCGCACCAT GCAGGCCCTG GAGATCGAGC TGCAGTCCCA GCTCAGCATG 
AAAGCATCCC TGGAGGGCAG CCTGGCAGAG ACAGAGAACC GCTACTGCGT GCAGCTGTCC 
CAGATCCAGG GTTTGATTGG CAGCGTGGAG GAGCAGCTGG CTCAGCTGCG CTGCGAGATG 
GAGCAGCAGA ATCAGGAGTA CAAGATCCTG CTGGATGTGA AGACTCGGCT GGAGCAGGAG 
ATCGCCACCT ACCGCCGTCT GCTGGAGGGC GAGGATGCCC ACCTGACTCA GTACAAGCCA 
AAAGAACCTG TGACCACCCG CCAGGTGCGC ACCATTGTGG AAGAGGTCCA GGATGGCAAG 
GTCATCTCAT CCCGGGAGCA GGTCCACCAG ACCACCCGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_997710.1
CDS	54..1355
Translation	MTTTIRQFTSSSSIKGSSGLGGGSSRTSCRLSGSLGAGSCRLGSASGLGSALGGNSYSSCYSFGTGSGYGGNFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQKQAPGPARDYSAYYQTIEDLKNKILVATVDNASILLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILSEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGSLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLTQYKPKEPVTTRQVRTIVEEVQDGKVISSREQVHQTTR

Target ORF information:

RefSeq Version	NM_212545.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus keratin 17 (Krt17), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_212545.2

ORF Insert Sequence:

ATGACTACCA CCATCCGCCA GTTCACGTCC TCCAGCTCCA TCAAGGGCTC CTCTGGCCTG 
GGTGGCGGCT CATCTAGGAC CTCCTGCCGA CTGTCTGGCA GCCTGGGTGC AGGCTCCTGC 
AGGCTGGGGT CAGCTAGTGG CCTGGGCAGT GCTCTTGGGG GCAACAGTTA CTCCAGCTGC 
TACAGCTTTG GTACTGGCAG TGGTTATGGA GGCAACTTTG GGGGTGTTGA TGGGCTGCTG 
GCTGGAGGGG AGAAGGCCAC CATGCAGAAC CTCAACGACC GCCTGGCCTC CTACCTGGAC 
AAGGTGCGTG CCCTGGAAGA GGCCAACACC GAGCTGGAGG TGAAGATCCG AGACTGGTAC 
CAGAAGCAGG CCCCAGGGCC AGCCCGCGAC TACAGTGCTT ATTACCAGAC CATTGAGGAT 
CTGAAGAACA AGATCCTCGT GGCCACTGTG GATAATGCCA GCATCCTACT CCAGATTGAC 
AATGCCCGCT TGGCAGCTGA TGACTTCCGT ACCAAGTTTG AGACGGAGCA GGCCCTGCGC 
ATGAGTGTGG AGGCGGACAT CAATGGCCTA CGCCGGGTGC TGGATGAGCT GACCCTGGCC 
AGAGCTGACC TGGAGATGCA GATTGAGAAT CTCAAGGAGG AGCTGGCCTA CCTGAAGAAG 
AACCATGAGG AGGAGATGAA TGCTCTGAGA GGCCAGGTGG GCGGCGAAAT CAACGTGGAG 
ATGGACGCAG CCCCTGGTGT GGACCTGAGC CGCATCCTGT CAGAGATGCG GGATCAGTAC 
GAGAAGATGG CTGAGAAGAA CCGCAAGGAT GCCGAAGATT GGTTCTTCAG CAAGACTGAG 
GAGCTAAACC GCGAGGTGGC CACCAACAGC GAGCTGGTGC AGAGCGGCAA GAGCGAGATC 
TCTGAGCTCC GGCGCACCAT GCAGGCCCTG GAGATCGAGC TGCAGTCCCA GCTCAGCATG 
AAAGCATCCC TGGAGGGCAG CCTGGCAGAG ACAGAGAACC GCTACTGCGT GCAGCTGTCC 
CAGATCCAGG GTTTGATTGG CAGCGTGGAG GAGCAGCTGG CTCAGCTGCG CTGCGAGATG 
GAGCAGCAGA ATCAGGAGTA CAAGATCCTG CTGGATGTGA AGACTCGGCT GGAGCAGGAG 
ATCGCCACCT ACCGCCGTCT GCTGGAGGGC GAGGATGCCC ACCTGACTCA GTACAAGCCA 
AAAGAACCTG TGACCACCCG CCAGGTGCGC ACCATTGTGG AAGAGGTCCA GGATGGCAAG 
GTCATCTCAT CCCGGGAGCA GGTCCACCAG ACCACCCGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects.
The Journal of allergy and clinical immunology132(5)1121-9(2013 Nov)
Saunders SP,Goh CS,Brown SJ,Palmer CN,Porter RM,Cole C,Campbell LE,Gierlinski M,Barton GJ,Schneider G,Balmain A,Prescott AR,Weidinger S,Baurecht H,Kabesch M,Gieger C,Lee YA,Tavendale R,Mukhopadhyay S,Turner SW,Madhok VB,Sullivan FM,Relton C,Burn J,Meggitt S,Smith CH,Allen MA,Barker JN,Reynolds NJ,Cordell HJ,Irvine AD,McLean WH,Sandilands A,Fallon PG

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Journal of proteome research8(3)1304-14(2009 Mar)
Gonzalez-Begne M,Lu B,Han X,Hagen FK,Hand AR,Melvin JE,Yates JR

The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles.
Current biology : CB16(10)1041-9(2006 May)
Andl T,Murchison EP,Liu F,Zhang Y,Yunta-Gonzalez M,Tobias JW,Andl CD,Seykora JT,Hannon GJ,Millar SE

Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion.
Genes & development20(10)1353-64(2006 May)
Tong X,Coulombe PA

A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth.
Nature441(7091)362-5(2006 May)
Kim S,Wong P,Coulombe PA