Ccr7 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ccr7
Entrez Gene ID	287673
Full Name	C-C motif chemokine receptor 7
General protein information	Preferred Names C-C motif chemokine receptor 7 Names C-C chemokine receptor type 7 chemokine (C-C motif) receptor 7
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q31
Summary	mouse homolog is a chemokine receptor; involved in the immune response to viruses [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_199489.4	NP_955783.1	C-C chemokine receptor type 7 precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	CCR7	NP_001020101.2
Danio rerio (zebrafish)	ccr7	NP_001092213.1
Pan troglodytes (chimpanzee)	CCR7	XP_511477.3
Macaca mulatta (Rhesus monkey)	CCR7	NP_001028056.1
Canis lupus familiaris (dog)	CCR7	XP_548131.2
Xenopus tropicalis (tropical clawed frog)	ccr7	XP_004918750.1
Homo sapiens (human)	CCR7	NP_001829.1
Mus musculus (house mouse)	Ccr7	NP_031745.2
Rattus norvegicus (Norway rat)	Ccr7	NP_955783.1
Gallus gallus (chicken)	CCR7	NP_001185681.1

Gene Ontology
Bibliography

Related articles in PubMed

CCR7 Is Important for Mesangial Cell Physiology and Repair.
Wurm S, Steege A, Rom-Jurek EM, van Roeyen CR, Kurtz A, Banas B, Banas MC
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society66(1)7-22(2018 01)

Upregulation of CC Chemokine Receptor 7 (CCR7) Enables Migration of Xenogeneic Human Adipose-Derived Mesenchymal Stem Cells to Rat Secondary Lymphoid Organs.
Ma T, Luan SL, Huang H, Sun XK, Yang YM, Zhang H, Han WD, Li H, Han Y
Medical science monitor : international medical journal of experimental and clinical research225206-5217(2016 Dec)

Matrix metalloproteinase-9 is up-regulated by CCL19/CCR7 interaction via PI3K/Akt pathway and is involved in CCL19-driven BMSCs migration.
Zhang W, Tu G, Lv C, Long J, Cong L, Han Y
Biochemical and biophysical research communications451(2)222-8(2014 Aug)

Differential requirement for CCR4 in the maintenance but not establishment of the invariant Vγ5(+) dendritic epidermal T-cell pool.
Nakamura K, White AJ, Parnell SM, Lane PJ, Jenkinson EJ, Jenkinson WE, Anderson G
PloS one8(9)e74019(2013)

CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration.
Chiang YJ, Ho KC, Sun CT, Chiu JJ, Lee FJ, Liao F, Yang-Yen HF, Yen JJ
PloS one8(4)e61761(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ccr7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ccr7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05365	NM_199489.4 Latest version!	Rattus norvegicus C-C motif chemokine receptor 7 (Ccr7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ccr7 ( NM_199489.4 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_955783.1 Rattus norvegicus C-C motif chemokine receptor 7 (Ccr7), mRNA.

Price & Availability↑

CloneID	ORa05365
Clone ID Related Accession (Same CDS sequence)	NM_199489.4
Accession Version	NM_199489.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1137bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565020800000
Organism	Rattus norvegicus(Norway rat)
Product	C-C chemokine receptor type 7 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY379972.1. On Aug 30, 2012 this sequence version replaced NM_199489.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY379972.1, BC089762.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689594, SAMEA2689599 [ECO:0000348] ##Evidence-Data-END##

ATGGACCTGG GGAAGCCCAC GAAAAACGTG CTGGTGGTGG CTCTCCTGGT CATTTTCCAG 
GTGTGCTTCT GCCAAGATGA GGTCACAGAC GACTACATCG GCGAGAACAC CACCGTGGAC 
TACACCCTGT ATGAGTCGGT GTGCTTCAAG AAGGATGTGC GGAACTTTAA GGCCTGGTTC 
CTCCCTCTCA TGTACTCAGT CATTTGCTTC GTGGGCCTGC TAGGCAATGG GCTGGTGGTG 
CTGACATACA TCTATTTCAA GAGACTGAAG ACCATGACGG ATACCTACCT GCTCAACCTG 
GCCGTGGCAG ACATCCTCTT CCTCATGATC CTTCCCTTCT GGGCCTACAG CGAAGCCAAG 
TCCTGGATCT TTGGTGCCTA CCTGTGTAAG AGCATCTTTG GCATCTACAA GTTAAGCTTC 
TTCAGCGGGA TGTTGCTGCT CCTGTGTATC AGCATTGACC GCTATGTGGC CATCGTCCAG 
GCCGTGTCAG CCCACCGGCA CCGCGCCCGC GTGCTTCTCA TCAGCAAGCT GTCCTGTATA 
GGCATCTGGA CGCTGGCCTT TTTCCTTTCT ATCCCTGAGC TGCTCTACAG CGGCCTCCAG 
AAGAACAGCG GCGAGGACAC GTGGAGATGC TCCCTGGTCA GTGCCCAAGT GGAGGCCTTG 
ATCGCCATCC AAGTGGCCCA GATGGTTGTT GGGTTTGTAC TGCCTATGCT GGCTATGAGT 
TTCTGCTACC TGGTTATCAT CCGCACTCTG CTCCAGGCGC GAAACTTCGA GCGGAACAAG 
GCCATCAAGG TGATCATCGC TGTGGTCGTA GTGTTCGTCG TCTTCCAGCT GCCCTACAAT 
GGGGTGGTCC TGGCCCAGAC CGTGGCCAAT TTCAACATCA CCAATAGCAG CTGCGAAGCC 
AGCAAGCAGC TCAACATTGC CTATGACGTC ACCTACAGCC TGGCCTCCGT CCGCTGCTGT 
GTCAACCCTT TCTTGTATGC CTTCATCGGC GTCAAGTTCC GCAGCGACCT CTTCAAGCTC 
TTCAAGGACT TGGGCTGCCT CAGCCAGGAA CGGCTCCGGC AGTGGTCTTC CTGCCGCCAT 
GTACGGCACA CGTCCGTGAG CATGGAGGCG GAGACTACCA CCACCTTCTC CCCGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_955783.1
CDS	79..1215
Translation	MDLGKPTKNVLVVALLVIFQVCFCQDEVTDDYIGENTTVDYTLYESVCFKKDVRNFKAWFLPLMYSVICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLMILPFWAYSEAKSWIFGAYLCKSIFGIYKLSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCIGIWTLAFFLSIPELLYSGLQKNSGEDTWRCSLVSAQVEALIAIQVAQMVVGFVLPMLAMSFCYLVIIRTLLQARNFERNKAIKVIIAVVVVFVVFQLPYNGVVLAQTVANFNITNSSCEASKQLNIAYDVTYSLASVRCCVNPFLYAFIGVKFRSDLFKLFKDLGCLSQERLRQWSSCRHVRHTSVSMEAETTTTFSP

Target ORF information:

RefSeq Version	NM_199489.4
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus C-C motif chemokine receptor 7 (Ccr7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_199489.4

ORF Insert Sequence:

ATGGACCTGG GGAAGCCCAC GAAAAACGTG CTGGTGGTGG CTCTCCTGGT CATTTTCCAG 
GTGTGCTTCT GCCAAGATGA GGTCACAGAC GACTACATCG GCGAGAACAC CACCGTGGAC 
TACACCCTGT ATGAGTCGGT GTGCTTCAAG AAGGATGTGC GGAACTTTAA GGCCTGGTTC 
CTCCCTCTCA TGTACTCAGT CATTTGCTTC GTGGGCCTGC TAGGCAATGG GCTGGTGGTG 
CTGACATACA TCTATTTCAA GAGACTGAAG ACCATGACGG ATACCTACCT GCTCAACCTG 
GCCGTGGCAG ACATCCTCTT CCTCATGATC CTTCCCTTCT GGGCCTACAG CGAAGCCAAG 
TCCTGGATCT TTGGTGCCTA CCTGTGTAAG AGCATCTTTG GCATCTACAA GTTAAGCTTC 
TTCAGCGGGA TGTTGCTGCT CCTGTGTATC AGCATTGACC GCTATGTGGC CATCGTCCAG 
GCCGTGTCAG CCCACCGGCA CCGCGCCCGC GTGCTTCTCA TCAGCAAGCT GTCCTGTATA 
GGCATCTGGA CGCTGGCCTT TTTCCTTTCT ATCCCTGAGC TGCTCTACAG CGGCCTCCAG 
AAGAACAGCG GCGAGGACAC GTGGAGATGC TCCCTGGTCA GTGCCCAAGT GGAGGCCTTG 
ATCGCCATCC AAGTGGCCCA GATGGTTGTT GGGTTTGTAC TGCCTATGCT GGCTATGAGT 
TTCTGCTACC TGGTTATCAT CCGCACTCTG CTCCAGGCGC GAAACTTCGA GCGGAACAAG 
GCCATCAAGG TGATCATCGC TGTGGTCGTA GTGTTCGTCG TCTTCCAGCT GCCCTACAAT 
GGGGTGGTCC TGGCCCAGAC CGTGGCCAAT TTCAACATCA CCAATAGCAG CTGCGAAGCC 
AGCAAGCAGC TCAACATTGC CTATGACGTC ACCTACAGCC TGGCCTCCGT CCGCTGCTGT 
GTCAACCCTT TCTTGTATGC CTTCATCGGC GTCAAGTTCC GCAGCGACCT CTTCAAGCTC 
TTCAAGGACT TGGGCTGCCT CAGCCAGGAA CGGCTCCGGC AGTGGTCTTC CTGCCGCCAT 
GTACGGCACA CGTCCGTGAG CATGGAGGCG GAGACTACCA CCACCTTCTC CCCGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

CCR7 Is Important for Mesangial Cell Physiology and Repair.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society66(1)7-22(2018 01)
Wurm S,Steege A,Rom-Jurek EM,van Roeyen CR,Kurtz A,Banas B,Banas MC

Upregulation of CC Chemokine Receptor 7 (CCR7) Enables Migration of Xenogeneic Human Adipose-Derived Mesenchymal Stem Cells to Rat Secondary Lymphoid Organs.
Medical science monitor : international medical journal of experimental and clinical research225206-5217(2016 Dec)
Ma T,Luan SL,Huang H,Sun XK,Yang YM,Zhang H,Han WD,Li H,Han Y

Matrix metalloproteinase-9 is up-regulated by CCL19/CCR7 interaction via PI3K/Akt pathway and is involved in CCL19-driven BMSCs migration.
Biochemical and biophysical research communications451(2)222-8(2014 Aug)
Zhang W,Tu G,Lv C,Long J,Cong L,Han Y

Differential requirement for CCR4 in the maintenance but not establishment of the invariant Vγ5(+) dendritic epidermal T-cell pool.
PloS one8(9)e74019(2013)
Nakamura K,White AJ,Parnell SM,Lane PJ,Jenkinson EJ,Jenkinson WE,Anderson G

CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration.
PloS one8(4)e61761(2013)
Chiang YJ,Ho KC,Sun CT,Chiu JJ,Lee FJ,Liao F,Yang-Yen HF,Yen JJ