Camk2n1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Camk2n1
Entrez Gene ID	287005
Full Name	calcium/calmodulin-dependent protein kinase II inhibitor 1
General protein information	Preferred Names calcium/calmodulin-dependent protein kinase II inhibitor 1 Names calcium/calmodulin-dependent protein kinase II inhibitor 1 CaM-kinase II inhibitor alpha caM-KIINalpha caMKIINalpha calcium/calmodulin-dependent protein kinase II inhibitor alpha
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q36
Summary	Ca2+/calmodulin-dependent-kinase II inhibitor protein [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_173337.1	NP_775459.1	calcium/calmodulin-dependent protein kinase II inhibitor 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CAMK2N1	XP_001160942.1
Mus musculus (house mouse)	Camk2n1	NP_079727.1
Bos taurus (cattle)	CAMK2N1	NP_001107992.1
Rattus norvegicus (Norway rat)	Camk2n1	NP_775459.1
Homo sapiens (human)	CAMK2N1	NP_061054.2
Macaca mulatta (Rhesus monkey)	CAMK2N1	XP_001095951.1

Gene Ontology
Bibliography

Related articles in PubMed

Optogenetic activation of the excitatory neurons expressing CaMKIIα in the ventral tegmental area upregulates the locomotor activity of free behaving rats.
Guo S, Chen S, Zhang Q, Wang Y, Xu K, Zheng X
BioMed research international2014687469(2014)

On the mechanism of synaptic depression induced by CaMKIIN, an endogenous inhibitor of CaMKII.
Gouet C, Aburto B, Vergara C, Sanhueza M
PloS one7(11)e49293(2012)

Novel insights into CaMKII function and regulation during memory formation.
Lucchesi W, Mizuno K, Giese KP
Brain research bulletin85(1-2)2-8(2011 Apr)

Controlling the cell cycle: the role of calcium/calmodulin-stimulated protein kinases I and II.
Skelding KA, Rostas JA, Verrills NM
Cell cycle (Georgetown, Tex.)10(4)631-9(2011 Feb)

A novel endogenous human CaMKII inhibitory protein suppresses tumor growth by inducing cell cycle arrest via p27 stabilization.
Wang C, Li N, Liu X, Zheng Y, Cao X
The Journal of biological chemistry283(17)11565-74(2008 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Camk2n1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Camk2n1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03747	NM_173337.1 Latest version!	Rattus norvegicus calcium/calmodulin-dependent protein kinase II inhibitor 1 (Camk2n1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Camk2n1 ( NM_173337.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_775459.1 Rattus norvegicus calcium/calmodulin-dependent protein kinase II inhibitor 1 (Camk2n1), mRNA.

Price & Availability↑

CloneID	ORa03747
Clone ID Related Accession (Same CDS sequence)	NM_173337.1
Accession Version	NM_173337.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 237bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1569168000000
Organism	Rattus norvegicus(Norway rat)
Product	calcium/calmodulin-dependent protein kinase II inhibitor 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF271156.1. ##Evidence-Data-START## Transcript exon combination :: AF271156.1, AA817703.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTCGGAGG TGCTGCCCTA CGGCGACGAG AAGCTGAGCC CCTACGGCGA CGGCGGCGAC 
GTGGGCCAGA TCTTCTCGTG CCGCCTGCAG GACACCAACA ACTTCTTCGG CGCCGGGCAG 
AGCAAGCGGC CGCCCAAGCT GGGCCAGATC GGCCGGAGCA AGCGCGTTGT TATTGAAGAT 
GATAGGATCG ATGACGTGCT GAAAACCATG ACCGACAAGG CACCTCCTGG TGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_775459.1
CDS	10..246
Translation	MSEVLPYGDEKLSPYGDGGDVGQIFSCRLQDTNNFFGAGQSKRPPKLGQIGRSKRVVIEDDRIDDVLKTMTDKAPPGV

Target ORF information:

RefSeq Version	NM_173337.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus calcium/calmodulin-dependent protein kinase II inhibitor 1 (Camk2n1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173337.1

ORF Insert Sequence:

ATGTCGGAGG TGCTGCCCTA CGGCGACGAG AAGCTGAGCC CCTACGGCGA CGGCGGCGAC 
GTGGGCCAGA TCTTCTCGTG CCGCCTGCAG GACACCAACA ACTTCTTCGG CGCCGGGCAG 
AGCAAGCGGC CGCCCAAGCT GGGCCAGATC GGCCGGAGCA AGCGCGTTGT TATTGAAGAT 
GATAGGATCG ATGACGTGCT GAAAACCATG ACCGACAAGG CACCTCCTGG TGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Optogenetic activation of the excitatory neurons expressing CaMKIIα in the ventral tegmental area upregulates the locomotor activity of free behaving rats.
BioMed research international2014687469(2014)
Guo S,Chen S,Zhang Q,Wang Y,Xu K,Zheng X

On the mechanism of synaptic depression induced by CaMKIIN, an endogenous inhibitor of CaMKII.
PloS one7(11)e49293(2012)
Gouet C,Aburto B,Vergara C,Sanhueza M

Novel insights into CaMKII function and regulation during memory formation.
Brain research bulletin85(1-2)2-8(2011 Apr)
Lucchesi W,Mizuno K,Giese KP

Controlling the cell cycle: the role of calcium/calmodulin-stimulated protein kinases I and II.
Cell cycle (Georgetown, Tex.)10(4)631-9(2011 Feb)
Skelding KA,Rostas JA,Verrills NM

A novel endogenous human CaMKII inhibitory protein suppresses tumor growth by inducing cell cycle arrest via p27 stabilization.
The Journal of biological chemistry283(17)11565-74(2008 Apr)
Wang C,Li N,Liu X,Zheng Y,Cao X