Wrnip1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Wrnip1
Entrez Gene ID	282835
Full Name	Werner helicase interacting protein 1
Synonyms	Whip,Wrnip
General protein information	Preferred Names Werner helicase interacting protein 1 Names ATPase WRNIP1 Werner syndrome homolog interacting protein werner helicase-interacting protein 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 17 Map Location: 17p12
Summary	human homolog binds WRN, a member of the RecQ family of DNA helicases that is mutated in Werner syndrome; may contribute to the premature aging phenotype in Werner syndrome [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_172332.2	NP_758835.1	ATPase WRNIP1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	WRNIP1	XP_005640033.1
Gallus gallus (chicken)	WRNIP1	XP_418979.2
Neurospora crassa	NCU08706	XP_963567.1
Schizosaccharomyces pombe (fission yeast)	SPAC26H5.02c	NP_594449.2
Homo sapiens (human)	WRNIP1	NP_064520.2
Eremothecium gossypii	AGOS_ABL183W	NP_982764.1
Macaca mulatta (Rhesus monkey)	WRNIP1	XP_001090684.1
Bos taurus (cattle)	WRNIP1	NP_001096576.1
Magnaporthe oryzae (rice blast fungus)	MGG_17505	XP_003718908.1
Xenopus tropicalis (tropical clawed frog)	wrnip1	NP_001121492.1
Kluyveromyces lactis	KLLA0D19360g	XP_453921.1
Mus musculus (house mouse)	Wrnip1	NP_084491.3
Danio rerio (zebrafish)	wrnip1	NP_998085.1
Saccharomyces cerevisiae (baker's yeast)	MGS1	NP_014181.1
Pan troglodytes (chimpanzee)	WRNIP1	XP_003950752.1
Rattus norvegicus (Norway rat)	Wrnip1	NP_758835.1
Arabidopsis thaliana (thale cress)	AT1G24290	NP_173839.1

Gene Ontology
Bibliography

Related articles in PubMed

A quantitative telomeric chromatin isolation protocol identifies different telomeric states.
Grolimund L, Aeby E, Hamelin R, Armand F, Chiappe D, Moniatte M, Lingner J
Nature communications42848(2013)

Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)

Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer.
Mano Y, Takahashi K, Ishikawa N, Takano A, Yasui W, Inai K, Nishimura H, Tsuchiya E, Nakamura Y, Daigo Y
Cancer science98(12)1902-13(2007 Dec)

Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta.
Tsurimoto T, Shinozaki A, Yano M, Seki M, Enomoto T
Genes to cells : devoted to molecular & cellular mechanisms10(1)13-22(2005 Jan)

A novel protein interacts with the Werner's syndrome gene product physically and functionally.
Kawabe Yi, Branzei D, Hayashi T, Suzuki H, Masuko T, Onoda F, Heo SJ, Ikeda H, Shimamoto A, Furuichi Y, Seki M, Enomoto T
The Journal of biological chemistry276(23)20364-9(2001 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Wrnip1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Wrnip1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03315	NM_172332.2 Latest version!	Rattus norvegicus WRN helicase interacting protein 1 (Wrnip1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Wrnip1 ( NM_172332.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_758835.1 Rattus norvegicus WRN helicase interacting protein 1 (Wrnip1), mRNA.

Price & Availability↑

CloneID	ORa03315
Clone ID Related Accession (Same CDS sequence)	NM_172332.2
Accession Version	NM_172332.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1983bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565539200000
Organism	Rattus norvegicus(Norway rat)
Product	ATPase WRNIP1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC098652.1. On Jul 13, 2005 this sequence version replaced NM_172332.1. ##Evidence-Data-START## Transcript exon combination :: BC098652.1, AY136827.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGTGA GCGGGCCGGA GGACGACCCC TTCCTGTCGC AGCTGCACCA GGTGCAATGC 
CCAGTGTGCC AGCAGATGAT GCCCGCCGCG CATATCAACT CGCACCTGGA CCGCTGCCTA 
CTGCTGCACC CTGCGGGGCA CGCGGAGCCA GCGGCCGGGC CTCATCGCGC TGGGGAGCGG 
GCTAAGGGGC CCTCGCCACC CGGCGCCAAG AGGCGTCGAC TGTCGGAGAG CTCGGCGCTG 
AAACAGCCTG CCACCCCGAC GGCGGCCGAA AGCAGCGAAG GCGAGGGCGA GGAGGGTGAC 
GACGGCGGCG AGACTGAGAG CCGTGAGAGC TACGACGCAC CGCCCACGCC CAGCGGTGCG 
CGCCTCATCC CGGACTTCCC GGTTGCCCGC TCCAGCAGCC CAGCTAGAAA GGGTTTGGGG 
AAGAGGCCAG CGGCTGCAGC CGCGGCGGGC AGTGCATCCC CGCGCAGCTG GGATGAGACG 
GAGGCGCAGG AAGAGGAGGA GGCGGGGGTG GACGGCGATG GCGACGCGGA CGTGGACGGT 
GAGGACGATC CTGGGCATTG GGATGCGGAC GCCGCCGATG CTTCGTTCGG AGTCAGCGCG 
GGTCGCGCAC ATCCTCGGGC ACTGCCGGCT GAAGAAATCC GACAGATGCT GGAGGGCAAG 
CCACTGGCTG ATAAGATGCG TCCCGATACG CTGCAGGACT ACATCGGGCA GAGTAGGGCG 
GTAGGGCAGG AGACGCTGCT CCGCTCGCTA TTGGAAACCA ACGAGATCCC CTCGCTCATC 
CTGTGGGGCC CACCAGGTTG CGGTAAGACC ACCTTGGCAC ACATCATAGC CAACAACAGC 
AAGAAGCACA GCATAAGGTT TGTGACATTA TCTGCAACAA ATGCCAAGAC AAATGACGTG 
AGGGATGTCA TAAAGCAAGC TCAGAATGAA AAGAGCTTTT TCAAAAGGAA AACCATCCTT 
TTTATTGATG AGATTCATCG TTTCAATAAA TCTCAGCAGG ACACTTTCCT TCCTCACGTG 
GAATGTGGGA CAATCACGCT GATTGGCGCA ACCACTGAGA ATCCTTCCTT CCAAGTCAAC 
ACCGCACTTC TGAGCCGCTG TCGGGTAATT GTTCTTGAGA AACTTCCAGT AGAGGCAATG 
GTGACGATTT TAATGAGAGC AATCAACTCA CTGGGAATCC ATGTGCTAGA CTCTAGCCGT 
CCTACTGACC CTCTGAGCCA CAGCAGCAAC TGCAGCTCTG AGCCCTCGGT CTTCATAGAA 
GATAAAGCAG TGGACACTCT GGCTTACCTC AGTGATGGTG ATGCCCGGAC TGGCTTAAAT 
GGACTGCAAC TGGCAGTGCT GGCCAGGTTA AGCTCTAGAA AGATGTTTTG TAAGAAGAGC 
GGTCAAACCT ATTCTCCTAG TCGAGTTCTG ATCACTGAGA ATGATGTGAA AGAAGGTCTA 
CAGCGGTCCC ACATTTTATA TGACCGAGCA GGAGAAGAGC ACTACAACTG CATCTCTGCC 
CTACACAAGG CTATGCGTGG CTCTGACCAG AATGCTTCCC TGTATTGGCT GGCCCGGATG 
CTTGAGGGAG GGGAGGACCC ACTCTATGTG GCCAGGAGGC TGGTAAGGTT TGCCAGCGAG 
GACATTGGTC TGGCAGATCC GTCAGCACTA GCCCAAGCGG TTGCTGCCTA CCAAGGCTGT 
CACTTTATAG GCATGCCCGA GTGTGAGGTG CTTCTGGCCC AGTGTGTGGT GTATTTTGCC 
AGAGCCCCAA AGTCCATTGA GGTGTACAGT GCCTATAACA ATGTAAAAGC CTGTCTGCGG 
AGCCACCAGG GGCCCCTGCC TCCTGTACCC CTGCACCTGA GGAATGCGCC CACCAGGCTG 
ATGAAGGATT TGGGTTATGG CAAAGGCTAC AAGTATAACC CCATGTACAG CGAGCCTGTG 
GACCAGGACT ACCTGCCTGA GGAACTGAGA GGAGTTGACT TCTTCAAGCA AAGGCGGTGT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_758835.1
CDS	186..2168
Translation	MEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHPAGHAEPAAGPHRAGERAKGPSPPGAKRRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPARKGLGKRPAAAAAAGSASPRSWDETEAQEEEEAGVDGDGDADVDGEDDPGHWDADAADASFGVSAGRAHPRALPAEEIRQMLEGKPLADKMRPDTLQDYIGQSRAVGQETLLRSLLETNEIPSLILWGPPGCGKTTLAHIIANNSKKHSIRFVTLSATNAKTNDVRDVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQDTFLPHVECGTITLIGATTENPSFQVNTALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSSRPTDPLSHSSNCSSEPSVFIEDKAVDTLAYLSDGDARTGLNGLQLAVLARLSSRKMFCKKSGQTYSPSRVLITENDVKEGLQRSHILYDRAGEEHYNCISALHKAMRGSDQNASLYWLARMLEGGEDPLYVARRLVRFASEDIGLADPSALAQAVAAYQGCHFIGMPECEVLLAQCVVYFARAPKSIEVYSAYNNVKACLRSHQGPLPPVPLHLRNAPTRLMKDLGYGKGYKYNPMYSEPVDQDYLPEELRGVDFFKQRRC

Target ORF information:

RefSeq Version	NM_172332.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus WRN helicase interacting protein 1 (Wrnip1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172332.2

ORF Insert Sequence:

ATGGAGGTGA GCGGGCCGGA GGACGACCCC TTCCTGTCGC AGCTGCACCA GGTGCAATGC 
CCAGTGTGCC AGCAGATGAT GCCCGCCGCG CATATCAACT CGCACCTGGA CCGCTGCCTA 
CTGCTGCACC CTGCGGGGCA CGCGGAGCCA GCGGCCGGGC CTCATCGCGC TGGGGAGCGG 
GCTAAGGGGC CCTCGCCACC CGGCGCCAAG AGGCGTCGAC TGTCGGAGAG CTCGGCGCTG 
AAACAGCCTG CCACCCCGAC GGCGGCCGAA AGCAGCGAAG GCGAGGGCGA GGAGGGTGAC 
GACGGCGGCG AGACTGAGAG CCGTGAGAGC TACGACGCAC CGCCCACGCC CAGCGGTGCG 
CGCCTCATCC CGGACTTCCC GGTTGCCCGC TCCAGCAGCC CAGCTAGAAA GGGTTTGGGG 
AAGAGGCCAG CGGCTGCAGC CGCGGCGGGC AGTGCATCCC CGCGCAGCTG GGATGAGACG 
GAGGCGCAGG AAGAGGAGGA GGCGGGGGTG GACGGCGATG GCGACGCGGA CGTGGACGGT 
GAGGACGATC CTGGGCATTG GGATGCGGAC GCCGCCGATG CTTCGTTCGG AGTCAGCGCG 
GGTCGCGCAC ATCCTCGGGC ACTGCCGGCT GAAGAAATCC GACAGATGCT GGAGGGCAAG 
CCACTGGCTG ATAAGATGCG TCCCGATACG CTGCAGGACT ACATCGGGCA GAGTAGGGCG 
GTAGGGCAGG AGACGCTGCT CCGCTCGCTA TTGGAAACCA ACGAGATCCC CTCGCTCATC 
CTGTGGGGCC CACCAGGTTG CGGTAAGACC ACCTTGGCAC ACATCATAGC CAACAACAGC 
AAGAAGCACA GCATAAGGTT TGTGACATTA TCTGCAACAA ATGCCAAGAC AAATGACGTG 
AGGGATGTCA TAAAGCAAGC TCAGAATGAA AAGAGCTTTT TCAAAAGGAA AACCATCCTT 
TTTATTGATG AGATTCATCG TTTCAATAAA TCTCAGCAGG ACACTTTCCT TCCTCACGTG 
GAATGTGGGA CAATCACGCT GATTGGCGCA ACCACTGAGA ATCCTTCCTT CCAAGTCAAC 
ACCGCACTTC TGAGCCGCTG TCGGGTAATT GTTCTTGAGA AACTTCCAGT AGAGGCAATG 
GTGACGATTT TAATGAGAGC AATCAACTCA CTGGGAATCC ATGTGCTAGA CTCTAGCCGT 
CCTACTGACC CTCTGAGCCA CAGCAGCAAC TGCAGCTCTG AGCCCTCGGT CTTCATAGAA 
GATAAAGCAG TGGACACTCT GGCTTACCTC AGTGATGGTG ATGCCCGGAC TGGCTTAAAT 
GGACTGCAAC TGGCAGTGCT GGCCAGGTTA AGCTCTAGAA AGATGTTTTG TAAGAAGAGC 
GGTCAAACCT ATTCTCCTAG TCGAGTTCTG ATCACTGAGA ATGATGTGAA AGAAGGTCTA 
CAGCGGTCCC ACATTTTATA TGACCGAGCA GGAGAAGAGC ACTACAACTG CATCTCTGCC 
CTACACAAGG CTATGCGTGG CTCTGACCAG AATGCTTCCC TGTATTGGCT GGCCCGGATG 
CTTGAGGGAG GGGAGGACCC ACTCTATGTG GCCAGGAGGC TGGTAAGGTT TGCCAGCGAG 
GACATTGGTC TGGCAGATCC GTCAGCACTA GCCCAAGCGG TTGCTGCCTA CCAAGGCTGT 
CACTTTATAG GCATGCCCGA GTGTGAGGTG CTTCTGGCCC AGTGTGTGGT GTATTTTGCC 
AGAGCCCCAA AGTCCATTGA GGTGTACAGT GCCTATAACA ATGTAAAAGC CTGTCTGCGG 
AGCCACCAGG GGCCCCTGCC TCCTGTACCC CTGCACCTGA GGAATGCGCC CACCAGGCTG 
ATGAAGGATT TGGGTTATGG CAAAGGCTAC AAGTATAACC CCATGTACAG CGAGCCTGTG 
GACCAGGACT ACCTGCCTGA GGAACTGAGA GGAGTTGACT TCTTCAAGCA AAGGCGGTGT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A quantitative telomeric chromatin isolation protocol identifies different telomeric states.
Nature communications42848(2013)
Grolimund L,Aeby E,Hamelin R,Armand F,Chiappe D,Moniatte M,Lingner J

Defining the membrane proteome of NK cells.
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Ghosh D,Lippert D,Krokhin O,Cortens JP,Wilkins JA

Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer.
Cancer science98(12)1902-13(2007 Dec)
Mano Y,Takahashi K,Ishikawa N,Takano A,Yasui W,Inai K,Nishimura H,Tsuchiya E,Nakamura Y,Daigo Y

Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta.
Genes to cells : devoted to molecular & cellular mechanisms10(1)13-22(2005 Jan)
Tsurimoto T,Shinozaki A,Yano M,Seki M,Enomoto T

A novel protein interacts with the Werner's syndrome gene product physically and functionally.
The Journal of biological chemistry276(23)20364-9(2001 Jun)
Kawabe Yi,Branzei D,Hayashi T,Suzuki H,Masuko T,Onoda F,Heo SJ,Ikeda H,Shimamoto A,Furuichi Y,Seki M,Enomoto T

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Wrnip1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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