Duox1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Duox1
Entrez Gene ID	266807
Full Name	dual oxidase 1
General protein information	Preferred Names dual oxidase 1 Names dual oxidase 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q35
Summary	human homolog is a NADPH oxidase of the thyroid [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_153739.1	NP_714961.1	dual oxidase 1 precursor
XM_006234829.3	XP_006234891.1	dual oxidase 1 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	DUOX1	XP_001163196.1
Arabidopsis thaliana (thale cress)	RBOHD	NP_199602.1
Arabidopsis thaliana (thale cress)	AT4G25090	NP_194239.2
Oryza sativa (rice)	Os01g0360200	NP_001043020.1
Mus musculus (house mouse)	Duox1	NP_001092767.1
Danio rerio (zebrafish)	duox	XP_001919394.4
Arabidopsis thaliana (thale cress)	RBOHA	NP_196356.1
Rattus norvegicus (Norway rat)	Duox1	NP_714961.1
Xenopus tropicalis (tropical clawed frog)	duox1	XP_002937936.2
Macaca mulatta (Rhesus monkey)	DUOX1	XP_001111370.1
Canis lupus familiaris (dog)	DUOX1	NP_001003122.1
Gallus gallus (chicken)	DUOX2	XP_425053.4
Homo sapiens (human)	DUOX1	NP_059130.2
Bos taurus (cattle)	DUOX1	NP_001192603.1
Arabidopsis thaliana (thale cress)	RHD2	NP_199919.1

Gene Ontology
Bibliography

Related articles in PubMed

The type of DUOX-dependent ROS production is dictated by defined sequences in DUOXA.
Hoste C, Dumont JE, Miot F, De Deken X
Experimental cell research318(18)2353-64(2012 Nov)

Mammalian numb-interacting protein 1/dual oxidase maturation factor 1 directs neuronal fate in stem cells.
Kennedy KA, Ostrakhovitch EA, Sandiford SD, Dayarathna T, Xie X, Waese EY, Chang WY, Feng Q, Skerjanc IS, Stanford WL, Li SS
The Journal of biological chemistry285(23)17974-85(2010 Jun)

Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells.
Luxen S, Noack D, Frausto M, Davanture S, Torbett BE, Knaus UG
Journal of cell science122(Pt 8)1238-47(2009 Apr)

Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium.
Harper RW, Xu C, Eiserich JP, Chen Y, Kao CY, Thai P, Setiadi H, Wu R
FEBS letters579(21)4911-7(2005 Aug)

Structural and functional characterization of the two human ThOX/Duox genes and their 5'-flanking regions.
Pachucki J, Wang D, Christophe D, Miot F
Molecular and cellular endocrinology214(1-2)53-62(2004 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Duox1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Duox1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03197	NM_153739.1 Latest version!	Rattus norvegicus dual oxidase 1 (Duox1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$811.30 $1159.00
ORa26266	XM_006234829.3 Latest version!	Rattus norvegicus dual oxidase 1 (Duox1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$811.30 $1159.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Duox1 ( NM_153739.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_714961.1 Rattus norvegicus dual oxidase 1 (Duox1), mRNA.

Price & Availability↑

CloneID	ORa03197
Clone ID Related Accession (Same CDS sequence)	NM_153739.1
Accession Version	NM_153739.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4656bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1555516800000
Organism	Rattus norvegicus(Norway rat)
Product	dual oxidase 1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF542180.1. On Jan 12, 2005 this sequence version replaced XM_346660.1. ##Evidence-Data-START## Transcript exon combination :: AF542180.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04563758, SAMN04563759 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGTCT ACTCAGCTGT GGCCTGGATC CTCCTTTTTG GGGTGCTGGC TTCTTTGGGA 
GCTCAGAATC CCGTTTCTTG GGAGGTCCAG CGATTTGATG GATGGTATAA CAACCTCATG 
GAGCACAGAT GGGGCAGCAA AGGCTCTCGG CTGCAGCGCC TTGTTCCGGC CAGCTATGCA 
GATGGTGTGT ACCAGCCCTT GAGAGAACCC TACCTGCCTA ACCCCCGACA CCTTAGCAAC 
AGGGTCATGA GAGGTCCCGC AGGGCAGCCG TCTCTTCGGA ACCGTACAGT CCTGGGTGTC 
TTCTTCGGCT ACCACGTGCT TTCAGACCTG GTGAGTGTGG AAACACCAGG CTGCCCCGCA 
GAGTTCCTCA ACATTTACAT CCCACGTGGG GACCCAGTGT TTGACCCTGA CAAGCGCGGG 
AACGTGGTGC TGCCCTTTCA GAGGAGCCGC TGGGACCGCA GCACTGGACA GAGCCCTAGC 
AACCCCCGAG ACCTGACCAA CCAGGTGACT GGCTGGCTAG ATGGCAGCGC CATCTATGGC 
TCCTCTCATT CCTGGAGCGA CACTCTGAGG AGCTTCTCTG GAGGACAGCT GGCTTCTGGC 
CCTGACCCTG CTTTCCCGAG GAACTCCCAG AACTCTCTGC TCATGTGGAT GGCACCAGAC 
CCCGCCACGG GGCAGGGCGG GCCACAGGGG CTGTATGCCT TCGGGGCTCA GCGCGGGAAC 
AGGGAGCCCT TTCTGCAGGC ACTGGGCTTG TTGTGGTTTC GATACCACAA CCTGTGTGCC 
AAGAGGCTGG CGCAGGAGCA CCCACACTGG GGGGATGAGG AGCTGTTCCA GCATGCTCGC 
AAGAGGGTCA TTGCCACTTA CCAGAACATT GCGATGTATG AGTGGCTGCC CAGCTTCCTG 
AAGCAAACGC CCCCAGAGTA TCCAGGATAC CATCCATTTC TGGACCCCAG CATCTCCCCA 
GAGTTCGTGG TGGCCTCAGA GCAGTTCCTC TCTACCATGG TGCCCCCTGG GGTCTACATG 
AGGAATGCCA GTTGCCACTT CCAGGGGATT GCCAATCGTA ACTCAAGTGT CTCTGGAGCT 
CTCCGGGTTT GCAACAGCTA CTGGAGTCGA GAGAACCCCA AGCTACAAAG GGCTGAAGAT 
GTGGATGCAT TGCTGCTGGG CATGGCCTCC CAGATTGCTG AGAGAGAGGA CCACCTAGTC 
GTTGAGGATG TGCAAGATTT TTGGCCCGGA CCACTGAAGT TTTCCCGTAC AGACTACCTG 
GCCAGCTGCC TGCAGAGGGG CCGGGATCTA GGTCTACCTT CATACACCAA AGCCAGGGAG 
GCACTGGGCC TGCCTCCTGT TTCCCACTGG CAGGACATCA ACCCTGCACT CTCGAGGAGC 
AATGGCACTG TGCTGGAGGC CACGGCTGCC CTGTACAATC AGGATCTGTC CCGGCTGGAG 
TTACTTGCTG GGGGGCTTCT GGAGAGCCAC GGAGACCCTG GACCCCTTTT CAGTGCTATT 
GTCCTTGACC AGTTTGTCAG GCTACGAGAT GGTGACCGCT ATTGGTTTGA AAACAACAGA 
AATGGATTGT TCTCTAAGGA AGAGATTGCA GAGATCCGAA ACACTTCCCT ACGGGATATT 
CTAGTGGCTG TCACCAACGT GGACCCCAGT GCCCTACAGC CCAGTGTCTT CTTTTGGCTT 
GCAGGAGACC CCTGTCCACA GCCAAGCCAG CTCAGCACCC AGGGCCTGCC AGCCTGTGCC 
CCCCTCTTCG TTCGGGACTA TTTCAAGGGG AGTGGATTTG GCTTCGGACT CACCATTGGG 
ACCCTTTGCT GCTTCCCCTT AGTCAGCCTC CTCAGTGCCT GGATTGTTGC CCGGCTTCGG 
ATGAGGAATT TCAAGAGGCT CCAGAGACAA GACCGCCAGA GCATCATGTG CGAGAAGCTT 
GTAGGGGGAG TGGAAGCTTT GGAGTGGCAG GGCCGCAAGG AACCCTGTAG GCCAGTGCTT 
GTGCACTTAC AGCCTGGACA GATCCGAGTC GTGGATGGCA GGCTCACTGT GCTCCGTACC 
ATCCAGCTGC GGCCCCCACA GCAGGTCAAC CTCATCCTGT CCAGCAACCG TGGACGCCGC 
ACCCTGCTGC TCAAGATCCC CAAGGAGTAC GACCTGGTGC TGTTGTTTAA CATGGAGGAG 
GAACGGCAGG CACTGGTGGA AAACATCAGG GCAGCTCTGA AGGAGAATGG ACTGAGCTTC 
CAGGAGTGGG AGCTGAGGGA GCAGGAGCTG ATGAGGGCAG CAGTGACCAG GCAACAGCGG 
GGTCACCTCC TGGAGACTTT TTTCAGGCAC CTTTTCTCCC AGGTGTTAGA CATCAATCAA 
GCAGATGCAG GGACTCTGCC ACTGGACTCT TCGACAAAAG TGCGTGAGGC TCTGACCTGC 
GAGCTGAGCA GAGCTGAGTT TGCGGACTCC CTAGGCCTCA AGCCCCAGGA TATGTTTGTG 
GAGTCCATGT TTTCTCTGGC CGACAAGGAC GGCAATGGCT ACCTGTCCTT CCGGGAGTTC 
CTGGACATCC TGGTGGTCTT CATGAAAGGC TCCCCAGAGG AGAAGTCTCG CCTCATGTTC 
CGAATGTATG ACTTTGACGG GAATGGTCTC ATCTCTAAGG ATGAGTTCAT TAGGATGCTA 
AGGTCCTTCA TCGAGATCTC CAACAACTGC CTGTCCAAGG ACCAGCTGGC TGAGGTGGTG 
GAGTCCATGT TCCGGGAGTC GGGCTTCCAG GACAAGGAGG AGCTGACCTG GGAGGACTTC 
CATTTCATGC TGCGCGACCA CGACAGCGAT CTCCGATTCA CACAGCTCTG TGTCAAAGGG 
GTGGAAGTGC CGGAAGTGAT CAAGAACCTC TGCCGGAGAG CCTCCTACAT CAGCCAGGAG 
AAGATCTGCC CTTCACCTAG AATGAGCGCC CATTGTGCCC GAAACAATAC GAAGACAGCG 
TCATCCCCAC AGAGACTGCA GTGCCCCGTG GACACGGACC CTCCTCAAGA GATTCGACGG 
AGGTTTGGCA AAAAGGTAAC TTCATTCCAG CCCTTACTGT TCACTGAGGC GCACCGAGAG 
AAGTTTCAAC GCAGCCGCCG CCACCAAACC GTGCAGCAGT TCAAGCGCTT CATTGAGAAC 
TACAGGCGCC ACATTGGCTG TGTGGCAGTG TTCTACACCA TCACTGGGGC GCTCTTCCTG 
GAGAGAGCCT ACTACTATGC GTTTGCCGCG CACCACAGCG GCATCACCGA TACTACCCGT 
GTGGGCATCA TCCTGTCCCG AGGCACGGCG GCCAGCATCT CCTTCATGTT TTCCTACATT 
TTGCTCACTA TGTGCCGCAA CCTCATCACC TTCCTGCGGG AGACCTTCCT CAACCGCTAC 
ATTCCCTTTG ATGCCGCTGT GGACTTCCAC CGCTTCATCG CCTCCACAGC CATCATCCTT 
ACAGTCTTAC ACAGTGCTGG CCACGTAGTG AATGTGTACC TGTTCTCCAT CAGCCCCCTC 
AGTGTCCTCT CTTGCCTCTT CCCTGACCTC TTCCACGATG ACGGGTCGGA GTTCCCTCAG 
AAGTATTACT GGTGGTTCTT CCAGACTGTG CCAGGTCTCA CTGGGGTCCT GCTGCTCCTG 
GCCCTGGCCA TCATGTATGT CTTCGCTTCC CACCACTTCC GCCGCCGCAG TTTCCGGGGC 
TTCTGGCTGA CCCACCACCT CTACATTTTT CTCTACATCC TGCTCATCAT CCATGGCAGC 
TTTGCTCTGA TCCAGATGCC CCGATTCCAC ATCTTCTTCC TGGTCCCCGC CATTATCTAT 
GTGGGGGACA AGCTGGTGAG CCTGAGCCGG AAGAAGGTGG AGATCAGCGT GGTGAAGGCT 
GAGCTGCTGC CTTCAGGAGT GACCCACCTG CGGTTCCAGA GGCCCCAGGG CTTTGAGTAT 
AAGTCAGGGC AGTGGGTTCG AATTGCATGC CTGGCTCTGG GAACCACCGA GTACCACCCT 
TTCACACTGA CTTCTGCACC CCACGAGGAC ACACTCAGCC TGCACATCCG GGCAGCTGGA 
CCCTGGACCA CCCGCCTCAG GGAGATCTAC TCACCCCCAA CGGGTGACAC CTGTGCCAGA 
TACCCAAAGC TGTACCTCGA TGGACCATTT GGAGAAGGCC ACCAGGAGTG GCATAAATTT 
GAGGTGTCAG TACTAGTGGG AGCTGGAATT GGGGTCACCC CCTTTGCCTC CATCCTCAAA 
GACCTGGTTT TCAAGTCATC AGTCAGCTGC CAAGTGTTCT GTAAGAAGAT CTACTTCATC 
TGGGTGACAA GGACTCAGCG GCAGTTTGAG TGGCTGGCTG ACATCATCCG GGAAGTTGAG 
GAGAATGACA GCCGGGACCT GGTGTCTGTG CACATCTATA TCACTCAGCT GGCTGAGAAG 
TTTGACCTCA GGACCACCAT GCTGTACATC TGTGAGAGGC ACTTCCAGAA GGTGCTGAAC 
AGGAGTCTGT TCACGGGCCT GCGCTCTGTC ACCCACTTTG GTCGCCCTCC CTTTGAGCCC 
TTTTTCAACT CTCTGCAGGA GGTCCACCCC CAAGTGCGAA AGATTGGAGT ATTTAGCTGT 
GGTCCCCCTG GCATGACCAA GAACGTGGAG AAGGCCTGTC AGCTCATCAA CAAGCAGGAT 
AGGACTCACT TCTCTCACCA TTATGAGAAC TTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_714961.1
CDS	29..4684
Translation	MAVYSAVAWILLFGVLASLGAQNPVSWEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLREPYLPNPRHLSNRVMRGPAGQPSLRNRTVLGVFFGYHVLSDLVSVETPGCPAEFLNIYIPRGDPVFDPDKRGNVVLPFQRSRWDRSTGQSPSNPRDLTNQVTGWLDGSAIYGSSHSWSDTLRSFSGGQLASGPDPAFPRNSQNSLLMWMAPDPATGQGGPQGLYAFGAQRGNREPFLQALGLLWFRYHNLCAKRLAQEHPHWGDEELFQHARKRVIATYQNIAMYEWLPSFLKQTPPEYPGYHPFLDPSISPEFVVASEQFLSTMVPPGVYMRNASCHFQGIANRNSSVSGALRVCNSYWSRENPKLQRAEDVDALLLGMASQIAEREDHLVVEDVQDFWPGPLKFSRTDYLASCLQRGRDLGLPSYTKAREALGLPPVSHWQDINPALSRSNGTVLEATAALYNQDLSRLELLAGGLLESHGDPGPLFSAIVLDQFVRLRDGDRYWFENNRNGLFSKEEIAEIRNTSLRDILVAVTNVDPSALQPSVFFWLAGDPCPQPSQLSTQGLPACAPLFVRDYFKGSGFGFGLTIGTLCCFPLVSLLSAWIVARLRMRNFKRLQRQDRQSIMCEKLVGGVEALEWQGRKEPCRPVLVHLQPGQIRVVDGRLTVLRTIQLRPPQQVNLILSSNRGRRTLLLKIPKEYDLVLLFNMEEERQALVENIRAALKENGLSFQEWELREQELMRAAVTRQQRGHLLETFFRHLFSQVLDINQADAGTLPLDSSTKVREALTCELSRAEFADSLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMKGSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCLSKDQLAEVVESMFRESGFQDKEELTWEDFHFMLRDHDSDLRFTQLCVKGVEVPEVIKNLCRRASYISQEKICPSPRMSAHCARNNTKTASSPQRLQCPVDTDPPQEIRRRFGKKVTSFQPLLFTEAHREKFQRSRRHQTVQQFKRFIENYRRHIGCVAVFYTITGALFLERAYYYAFAAHHSGITDTTRVGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYIPFDAAVDFHRFIASTAIILTVLHSAGHVVNVYLFSISPLSVLSCLFPDLFHDDGSEFPQKYYWWFFQTVPGLTGVLLLLALAIMYVFASHHFRRRSFRGFWLTHHLYIFLYILLIIHGSFALIQMPRFHIFFLVPAIIYVGDKLVSLSRKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHPFTLTSAPHEDTLSLHIRAAGPWTTRLREIYSPPTGDTCARYPKLYLDGPFGEGHQEWHKFEVSVLVGAGIGVTPFASILKDLVFKSSVSCQVFCKKIYFIWVTRTQRQFEWLADIIREVEENDSRDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSVTHFGRPPFEPFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINKQDRTHFSHHYENF

Target ORF information:

RefSeq Version	NM_153739.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual oxidase 1 (Duox1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153739.1

ORF Insert Sequence:

ATGGCAGTCT ACTCAGCTGT GGCCTGGATC CTCCTTTTTG GGGTGCTGGC TTCTTTGGGA 
GCTCAGAATC CCGTTTCTTG GGAGGTCCAG CGATTTGATG GATGGTATAA CAACCTCATG 
GAGCACAGAT GGGGCAGCAA AGGCTCTCGG CTGCAGCGCC TTGTTCCGGC CAGCTATGCA 
GATGGTGTGT ACCAGCCCTT GAGAGAACCC TACCTGCCTA ACCCCCGACA CCTTAGCAAC 
AGGGTCATGA GAGGTCCCGC AGGGCAGCCG TCTCTTCGGA ACCGTACAGT CCTGGGTGTC 
TTCTTCGGCT ACCACGTGCT TTCAGACCTG GTGAGTGTGG AAACACCAGG CTGCCCCGCA 
GAGTTCCTCA ACATTTACAT CCCACGTGGG GACCCAGTGT TTGACCCTGA CAAGCGCGGG 
AACGTGGTGC TGCCCTTTCA GAGGAGCCGC TGGGACCGCA GCACTGGACA GAGCCCTAGC 
AACCCCCGAG ACCTGACCAA CCAGGTGACT GGCTGGCTAG ATGGCAGCGC CATCTATGGC 
TCCTCTCATT CCTGGAGCGA CACTCTGAGG AGCTTCTCTG GAGGACAGCT GGCTTCTGGC 
CCTGACCCTG CTTTCCCGAG GAACTCCCAG AACTCTCTGC TCATGTGGAT GGCACCAGAC 
CCCGCCACGG GGCAGGGCGG GCCACAGGGG CTGTATGCCT TCGGGGCTCA GCGCGGGAAC 
AGGGAGCCCT TTCTGCAGGC ACTGGGCTTG TTGTGGTTTC GATACCACAA CCTGTGTGCC 
AAGAGGCTGG CGCAGGAGCA CCCACACTGG GGGGATGAGG AGCTGTTCCA GCATGCTCGC 
AAGAGGGTCA TTGCCACTTA CCAGAACATT GCGATGTATG AGTGGCTGCC CAGCTTCCTG 
AAGCAAACGC CCCCAGAGTA TCCAGGATAC CATCCATTTC TGGACCCCAG CATCTCCCCA 
GAGTTCGTGG TGGCCTCAGA GCAGTTCCTC TCTACCATGG TGCCCCCTGG GGTCTACATG 
AGGAATGCCA GTTGCCACTT CCAGGGGATT GCCAATCGTA ACTCAAGTGT CTCTGGAGCT 
CTCCGGGTTT GCAACAGCTA CTGGAGTCGA GAGAACCCCA AGCTACAAAG GGCTGAAGAT 
GTGGATGCAT TGCTGCTGGG CATGGCCTCC CAGATTGCTG AGAGAGAGGA CCACCTAGTC 
GTTGAGGATG TGCAAGATTT TTGGCCCGGA CCACTGAAGT TTTCCCGTAC AGACTACCTG 
GCCAGCTGCC TGCAGAGGGG CCGGGATCTA GGTCTACCTT CATACACCAA AGCCAGGGAG 
GCACTGGGCC TGCCTCCTGT TTCCCACTGG CAGGACATCA ACCCTGCACT CTCGAGGAGC 
AATGGCACTG TGCTGGAGGC CACGGCTGCC CTGTACAATC AGGATCTGTC CCGGCTGGAG 
TTACTTGCTG GGGGGCTTCT GGAGAGCCAC GGAGACCCTG GACCCCTTTT CAGTGCTATT 
GTCCTTGACC AGTTTGTCAG GCTACGAGAT GGTGACCGCT ATTGGTTTGA AAACAACAGA 
AATGGATTGT TCTCTAAGGA AGAGATTGCA GAGATCCGAA ACACTTCCCT ACGGGATATT 
CTAGTGGCTG TCACCAACGT GGACCCCAGT GCCCTACAGC CCAGTGTCTT CTTTTGGCTT 
GCAGGAGACC CCTGTCCACA GCCAAGCCAG CTCAGCACCC AGGGCCTGCC AGCCTGTGCC 
CCCCTCTTCG TTCGGGACTA TTTCAAGGGG AGTGGATTTG GCTTCGGACT CACCATTGGG 
ACCCTTTGCT GCTTCCCCTT AGTCAGCCTC CTCAGTGCCT GGATTGTTGC CCGGCTTCGG 
ATGAGGAATT TCAAGAGGCT CCAGAGACAA GACCGCCAGA GCATCATGTG CGAGAAGCTT 
GTAGGGGGAG TGGAAGCTTT GGAGTGGCAG GGCCGCAAGG AACCCTGTAG GCCAGTGCTT 
GTGCACTTAC AGCCTGGACA GATCCGAGTC GTGGATGGCA GGCTCACTGT GCTCCGTACC 
ATCCAGCTGC GGCCCCCACA GCAGGTCAAC CTCATCCTGT CCAGCAACCG TGGACGCCGC 
ACCCTGCTGC TCAAGATCCC CAAGGAGTAC GACCTGGTGC TGTTGTTTAA CATGGAGGAG 
GAACGGCAGG CACTGGTGGA AAACATCAGG GCAGCTCTGA AGGAGAATGG ACTGAGCTTC 
CAGGAGTGGG AGCTGAGGGA GCAGGAGCTG ATGAGGGCAG CAGTGACCAG GCAACAGCGG 
GGTCACCTCC TGGAGACTTT TTTCAGGCAC CTTTTCTCCC AGGTGTTAGA CATCAATCAA 
GCAGATGCAG GGACTCTGCC ACTGGACTCT TCGACAAAAG TGCGTGAGGC TCTGACCTGC 
GAGCTGAGCA GAGCTGAGTT TGCGGACTCC CTAGGCCTCA AGCCCCAGGA TATGTTTGTG 
GAGTCCATGT TTTCTCTGGC CGACAAGGAC GGCAATGGCT ACCTGTCCTT CCGGGAGTTC 
CTGGACATCC TGGTGGTCTT CATGAAAGGC TCCCCAGAGG AGAAGTCTCG CCTCATGTTC 
CGAATGTATG ACTTTGACGG GAATGGTCTC ATCTCTAAGG ATGAGTTCAT TAGGATGCTA 
AGGTCCTTCA TCGAGATCTC CAACAACTGC CTGTCCAAGG ACCAGCTGGC TGAGGTGGTG 
GAGTCCATGT TCCGGGAGTC GGGCTTCCAG GACAAGGAGG AGCTGACCTG GGAGGACTTC 
CATTTCATGC TGCGCGACCA CGACAGCGAT CTCCGATTCA CACAGCTCTG TGTCAAAGGG 
GTGGAAGTGC CGGAAGTGAT CAAGAACCTC TGCCGGAGAG CCTCCTACAT CAGCCAGGAG 
AAGATCTGCC CTTCACCTAG AATGAGCGCC CATTGTGCCC GAAACAATAC GAAGACAGCG 
TCATCCCCAC AGAGACTGCA GTGCCCCGTG GACACGGACC CTCCTCAAGA GATTCGACGG 
AGGTTTGGCA AAAAGGTAAC TTCATTCCAG CCCTTACTGT TCACTGAGGC GCACCGAGAG 
AAGTTTCAAC GCAGCCGCCG CCACCAAACC GTGCAGCAGT TCAAGCGCTT CATTGAGAAC 
TACAGGCGCC ACATTGGCTG TGTGGCAGTG TTCTACACCA TCACTGGGGC GCTCTTCCTG 
GAGAGAGCCT ACTACTATGC GTTTGCCGCG CACCACAGCG GCATCACCGA TACTACCCGT 
GTGGGCATCA TCCTGTCCCG AGGCACGGCG GCCAGCATCT CCTTCATGTT TTCCTACATT 
TTGCTCACTA TGTGCCGCAA CCTCATCACC TTCCTGCGGG AGACCTTCCT CAACCGCTAC 
ATTCCCTTTG ATGCCGCTGT GGACTTCCAC CGCTTCATCG CCTCCACAGC CATCATCCTT 
ACAGTCTTAC ACAGTGCTGG CCACGTAGTG AATGTGTACC TGTTCTCCAT CAGCCCCCTC 
AGTGTCCTCT CTTGCCTCTT CCCTGACCTC TTCCACGATG ACGGGTCGGA GTTCCCTCAG 
AAGTATTACT GGTGGTTCTT CCAGACTGTG CCAGGTCTCA CTGGGGTCCT GCTGCTCCTG 
GCCCTGGCCA TCATGTATGT CTTCGCTTCC CACCACTTCC GCCGCCGCAG TTTCCGGGGC 
TTCTGGCTGA CCCACCACCT CTACATTTTT CTCTACATCC TGCTCATCAT CCATGGCAGC 
TTTGCTCTGA TCCAGATGCC CCGATTCCAC ATCTTCTTCC TGGTCCCCGC CATTATCTAT 
GTGGGGGACA AGCTGGTGAG CCTGAGCCGG AAGAAGGTGG AGATCAGCGT GGTGAAGGCT 
GAGCTGCTGC CTTCAGGAGT GACCCACCTG CGGTTCCAGA GGCCCCAGGG CTTTGAGTAT 
AAGTCAGGGC AGTGGGTTCG AATTGCATGC CTGGCTCTGG GAACCACCGA GTACCACCCT 
TTCACACTGA CTTCTGCACC CCACGAGGAC ACACTCAGCC TGCACATCCG GGCAGCTGGA 
CCCTGGACCA CCCGCCTCAG GGAGATCTAC TCACCCCCAA CGGGTGACAC CTGTGCCAGA 
TACCCAAAGC TGTACCTCGA TGGACCATTT GGAGAAGGCC ACCAGGAGTG GCATAAATTT 
GAGGTGTCAG TACTAGTGGG AGCTGGAATT GGGGTCACCC CCTTTGCCTC CATCCTCAAA 
GACCTGGTTT TCAAGTCATC AGTCAGCTGC CAAGTGTTCT GTAAGAAGAT CTACTTCATC 
TGGGTGACAA GGACTCAGCG GCAGTTTGAG TGGCTGGCTG ACATCATCCG GGAAGTTGAG 
GAGAATGACA GCCGGGACCT GGTGTCTGTG CACATCTATA TCACTCAGCT GGCTGAGAAG 
TTTGACCTCA GGACCACCAT GCTGTACATC TGTGAGAGGC ACTTCCAGAA GGTGCTGAAC 
AGGAGTCTGT TCACGGGCCT GCGCTCTGTC ACCCACTTTG GTCGCCCTCC CTTTGAGCCC 
TTTTTCAACT CTCTGCAGGA GGTCCACCCC CAAGTGCGAA AGATTGGAGT ATTTAGCTGT 
GGTCCCCCTG GCATGACCAA GAACGTGGAG AAGGCCTGTC AGCTCATCAA CAAGCAGGAT 
AGGACTCACT TCTCTCACCA TTATGAGAAC TTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Duox1 ( XM_006234829.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006234891.1 Rattus norvegicus dual oxidase 1 (Duox1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa26266
Clone ID Related Accession (Same CDS sequence)	XM_006234829.3
Accession Version	XM_006234829.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4656bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	dual oxidase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006234829.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGTCT ACTCAGCTGT GGCCTGGATC CTCCTTTTTG GGATGCTGGC TTCTTTGGGA 
GCTCAGAATT CCGTTTCTTG GGAGGTCCAG CGATTTGATG GATGGTATAA CAACCTCATG 
GAGCACAGAT GGGGCAGCAA AGGCTCTCGG CTGCAGCGCC TTGTTCCGGC CAGCTATGCA 
GATGGTGTGT ACCAGCCCTT GAGAGAACCC TACCTGCCTA ACCCCCGACA CCTTAGCAAC 
AGGGTCATGA GAGGTCCCGC AGGGCAGCCG TCTCTTCGGA ACCGTACAGT CCTGGGTGTC 
TTCTTCGGCT ACCACGTGCT TTCAGACCTG GTGAGTGTGG AAACACCAGG CTGCCCCGCA 
GAGTTCCTCA ACATTTACAT CCCACGTGGG GACCCAGTGT TTGACCCTGA CAAGCGCGGG 
AACGTGGTGC TGCCCTTTCA GAGGAGCCGC TGGGACCGCA GCACTGGACA GAGCCCTAGC 
AACCCCCGAG ACCTGACCAA CCAGGTGACT GGCTGGCTAG ATGGCAGCGC CATCTATGGC 
TCCTCTCATT CCTGGAGCGA CACTCTGAGG AGCTTCTCTG GAGGACAGCT GGCTTCTGGC 
CCTGACCCTG CTTTCCCGAG GAACTCCCAG AACTCTCTGC TCATGTGGAT GGCACCAGAC 
CCCGCCACGG GGCAGGGCGG GCCACAGGGG CTGTATGCCT TCGGGGCCCA GCGCGGGAAC 
AGGGAGCCCT TTCTGCAGGC ACTGGGCTTG TTGTGGTTTC GATACCACAA CCTGTGTGCC 
AAGAGGCTGG CGCAGGAGCA CCCACACTGG GGGGATGAGG AGCTGTTCCA GCATGCTCGC 
AAGAGGGTCA TTGCCACTTA CCAGAACATT GCGATGTATG AGTGGCTGCC CAGCTTCCTG 
AAGCAAACGC CCCCAGAGTA TCCAGGATAC CATCCATTTC TGGACCCCAG CATCTCCCCA 
GAGTTCGTGG TGGCCTCAGA GCAGTTCCTC TCTACCATGG TGCCCCCTGG GGTCTACATG 
AGGAATGCCA GTTGCCACTT CCAGGGGATT GCCAATCGTA ACTCAAGTGT CTCTGGAGCT 
CTCCGGGTTT GCAACAGCTA CTGGAGTCGA GAGAACCCCA AGCTACAAAG GGCTGAAGAT 
GTGGATGCAT TGCTGCTGGG CATGGCCTCC CAGATTGCTG AGAGAGAGGA CCACCTAGTC 
GTTGAGGATG TGCAAGATTT TTGGCCCGGA CCACTGAAGT TTTCCCGTAC AGACTACCTG 
GCCAGCTGCC TGCAGAGGGG CCGGGATCTA GGCCTACCTT CATACACCAA AGCCAGGGAG 
GCACTGGGCC TGCCTCCTGT TTCCCACTGG CAGGACATCA ACCCTGCACT CTCGAGGAGC 
AATGGCACTG TGCTGGAGGC CACGGCTGCC CTGTACAATC AGGATCTGTC CCGGCTGGAG 
TTACTTGCTG GGGGGCTTCT GGAGAGCCAC GGAGACCCTG GACCCCTTTT CAGTGCTATT 
GTCCTTGACC AGTTTGTCAG GCTACGAGAT GGTGACCGCT ATTGGTTTGA AAACAACAGA 
AATGGATTGT TCTCTAAGGA AGAGATTGCA GAGATCCGAA ACACTTCCCT ACGGGATATT 
CTAGTGGCTG TCACCAACGT GGACCCCAGT GCCCTACAGC CCAGTGTCTT CTTTTGGCTT 
GCAGGAGACC CCTGTCCACA GCCAAGCCAG CTCAGCACCC AGGGCCTGCC AGCCTGTGCC 
CCCCTCTTCG TTCGGGACTA TTTCAAGGGG AGTGGATTTG GCTTCGGACT CACCATTGGG 
ACCCTTTGCT GCTTCCCCTT AGTCAGCCTC CTCAGTGCCT GGATTGTTGC CCGGCTTCGG 
ATGAGGAATT TCAAGAGGCT CCAGAGACAA GACCGCCAGA GCATCATGTG CGAGAAGCTT 
GTAGGGGGAG TGGAAGCTTT GGAGTGGCAG GGCCGCAAGG AACCCTGTAG GCCAGTGCTT 
GTGCACTTAC AGCCTGGACA GATCCGAGTC GTGGATGGCA GGCTCACTGT GCTCCGTACC 
ATCCAGCTGC GGCCCCCACA GCAGGTCAAC CTCATCCTGT CCAGCAACCG TGGACGCCGC 
ACCCTGCTGC TCAAGATCCC CAAGGAGTAC GACCTGGTGC TGTTGTTTAA CATGGAGGAG 
GAACGGCAGG CACTGGTGGA AAACATCAGG GCAGCTCTGA AGGAGAATGG ACTGAGCTTC 
CAGGAGTGGG AGCTGAGGGA GCAGGAGCTG ATGAGGGCAG CAGTGACCAG GCAACAGCGG 
GGTCACCTCC TGGAGACTTT TTTCAGGCAC CTTTTCTCCC AGGTGTTAGA CATCAATCAA 
GCAGATGCAG GGACTCTGCC ACTGGACTCT TCGACAAAAG TGCGTGAGGC TCTGACCTGC 
GAGCTGAGCA GAGCTGAGTT TGCGGACTCC CTAGGCCTCA AGCCCCAGGA TATGTTTGTG 
GAGTCCATGT TTTCTCTGGC CGACAAGGAT GGCAATGGCT ACCTGTCCTT CCGGGAGTTC 
CTGGACATCC TGGTGGTCTT CATGAAAGGC TCCCCAGAGG AGAAGTCTCG CCTCATGTTC 
CGAATGTATG ACTTTGACGG GAATGGTCTC ATCTCTAAGG ATGAGTTCAT TAGGATGCTA 
AGGTCCTTCA TCGAGATCTC CAACAACTGC CTGTCCAAGG ACCAGCTGGC TGAGGTGGTG 
GAGTCCATGT TCTGGGAGTC GGGCTTCCAG GACAAGGAGG AGCTGACCTG GGAGGACTTC 
CATTTCATGC TGCGCGACCA CGACAGCGAT CTCCGATTCA CACAGCTCTG TGTCAAAGGG 
GTGGAAGTGC CGGAAGTGAT CAAGAACCTC TGCCGGAGAG CCTCCTACAT CAGCCAGGAG 
AAGATCTGCC CTTCACCTAG AATGAGCGCC CATTGTGCCC GAAACAATAC GAAGACAGCG 
TCATCCCCAC AGAGACTGCA GTGCCCCGTG GACACGGACC CTCCTCAAGA GATTCGACGG 
AGGTTTGGCA AAAAGGTAAC TTCATTCCAG CCCTTACTGT TCACTGAGGC GCACCGAGAG 
AAGTTTCAAC GCAGCCGCCG CCACCAAACC GTGCAGCAGT TCAAGCGCTT CATTGAGAAC 
TACAGGCGCC ACATTGGCTG TGTGGCAGTG TTCTACACCA TCACTGGGGC GCTCTTCCTG 
GAGAGAGCCT ACTACTATGC GTTTGCCGCG CACCACAGCG GCATCACCGA TACTACCCGT 
GTGGGCATCA TCCTGTCCCG AGGCACGGCG GCCAGCATCT CCTTCATGTT TTCCTACATT 
TTGCTCACTA TGTGCCGCAA CCTCATCACC TTCCTGCGGG AGACCTTCCT CAACCGCTAC 
ATTCCCTTTG ATGCCGCTGT GGACTTCCAC CGCTTCATCG CCTCCACAGC CATCATCCTT 
ACAGTCTTAC ACAGTGCTGG CCACGTAGTG AATGTGTACC TGTTCTCCAT CAGCCCCCTC 
AGTGTCCTCT CTTGCCTCTT CCCTGACCTC TTCCACGATG ACGGGTCGGA GTTCCCTCAG 
AAGTATTACT GGTGGTTCTT CCAGACTGTG CCAGGTCTCA CTGGGGTCCT GCTGCTCCTG 
GCCCTGGCCA TCATGTATGT CTTCGCTTCC CACCACTTCC GCCGCCGCAG TTTCCGGGGC 
TTCTGGCTGA CCCACCACCT CTACATTTTT CTCTACATCC TGCTCATCAT CCATGGCAGC 
TTTGCTCTGA TCCAGATGCC CCGATTCCAC ATCTTCTTCC TGGTCCCCGC CATTATCTAT 
GTGGGGGACA AGCTGGTGAG CCTGAGCCGG AAGAAGGTGG AGATCAGCGT GGTGAAGGCT 
GAGCTGCTGC CTTCAGGAGT GACCCACCTG CGGTTCCAGA GGCCCCAGGG CTTTGAGTAT 
AAGTCAGGGC AGTGGGTTCG AATTGCATGC CTGGCTCTGG GAACCACCGA GTACCACCCT 
TTCACACTGA CTTCTGCACC CCACGAGGAC ACACTCAGCC TGCACATCCG GGCAGCTGGA 
CCCTGGACCA CCCGCCTCAG GGAGATCTAC TCACCCCCAA CGGGTGACAC CTGTGCCAGA 
TACCCAAAGC TGTACCTCGA TGGACCATTT GGAGAAGGCC ACCAGGAGTG GCATAAATTT 
GAGGTGTCAG TACTAGTGGG AGCTGGAATT GGGGTCACCC CCTTTGCCTC CATCCTCAAA 
GACCTGGTTT TCAAGTCATC AGTCAGCTGC CAAGTGTTCT GTAAGAAGAT CTACTTCATC 
TGGGTGACAA GGACTCAGCG GCAGTTTGAG TGGCTGGCTG ACATCATCCG GGAAGTTGAG 
GAGAATGACA GCCGGGACCT GGTGTCTGTG CACATCTATA TCACTCAGCT GGCTGAGAAG 
TTTGACCTCA GGACCACCAT GCTGTACATC TGTGAGAGGC ACTTCCAGAA GGTGCTGAAC 
AGGAGTCTGT TCACGGGCCT GCGCTCTGTC ACCCACTTTG GTCGCCCTCC CTTTGAGCCC 
TTTTTCAACT CTCTGCAGGA GGTCCACCCC CAAGTGCGAA AGATTGGAGT ATTTAGCTGT 
GGTCCCCCTG GCATGACCAA GAACGTGGAG AAGGCCTGTC AGCTCATCAA CAAGCAGGAT 
AGGACTCACT TCTCTCACCA TTATGAGAAC TTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006234891.1
CDS	152..4807
Translation	MAVYSAVAWILLFGMLASLGAQNSVSWEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLREPYLPNPRHLSNRVMRGPAGQPSLRNRTVLGVFFGYHVLSDLVSVETPGCPAEFLNIYIPRGDPVFDPDKRGNVVLPFQRSRWDRSTGQSPSNPRDLTNQVTGWLDGSAIYGSSHSWSDTLRSFSGGQLASGPDPAFPRNSQNSLLMWMAPDPATGQGGPQGLYAFGAQRGNREPFLQALGLLWFRYHNLCAKRLAQEHPHWGDEELFQHARKRVIATYQNIAMYEWLPSFLKQTPPEYPGYHPFLDPSISPEFVVASEQFLSTMVPPGVYMRNASCHFQGIANRNSSVSGALRVCNSYWSRENPKLQRAEDVDALLLGMASQIAEREDHLVVEDVQDFWPGPLKFSRTDYLASCLQRGRDLGLPSYTKAREALGLPPVSHWQDINPALSRSNGTVLEATAALYNQDLSRLELLAGGLLESHGDPGPLFSAIVLDQFVRLRDGDRYWFENNRNGLFSKEEIAEIRNTSLRDILVAVTNVDPSALQPSVFFWLAGDPCPQPSQLSTQGLPACAPLFVRDYFKGSGFGFGLTIGTLCCFPLVSLLSAWIVARLRMRNFKRLQRQDRQSIMCEKLVGGVEALEWQGRKEPCRPVLVHLQPGQIRVVDGRLTVLRTIQLRPPQQVNLILSSNRGRRTLLLKIPKEYDLVLLFNMEEERQALVENIRAALKENGLSFQEWELREQELMRAAVTRQQRGHLLETFFRHLFSQVLDINQADAGTLPLDSSTKVREALTCELSRAEFADSLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMKGSPEEKSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCLSKDQLAEVVESMFWESGFQDKEELTWEDFHFMLRDHDSDLRFTQLCVKGVEVPEVIKNLCRRASYISQEKICPSPRMSAHCARNNTKTASSPQRLQCPVDTDPPQEIRRRFGKKVTSFQPLLFTEAHREKFQRSRRHQTVQQFKRFIENYRRHIGCVAVFYTITGALFLERAYYYAFAAHHSGITDTTRVGIILSRGTAASISFMFSYILLTMCRNLITFLRETFLNRYIPFDAAVDFHRFIASTAIILTVLHSAGHVVNVYLFSISPLSVLSCLFPDLFHDDGSEFPQKYYWWFFQTVPGLTGVLLLLALAIMYVFASHHFRRRSFRGFWLTHHLYIFLYILLIIHGSFALIQMPRFHIFFLVPAIIYVGDKLVSLSRKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHPFTLTSAPHEDTLSLHIRAAGPWTTRLREIYSPPTGDTCARYPKLYLDGPFGEGHQEWHKFEVSVLVGAGIGVTPFASILKDLVFKSSVSCQVFCKKIYFIWVTRTQRQFEWLADIIREVEENDSRDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSVTHFGRPPFEPFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINKQDRTHFSHHYENF

Target ORF information:

RefSeq Version	XM_006234829.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dual oxidase 1 (Duox1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006234829.3

ORF Insert Sequence:

ATGGCAGTCT ACTCAGCTGT GGCCTGGATC CTCCTTTTTG GGATGCTGGC TTCTTTGGGA 
GCTCAGAATT CCGTTTCTTG GGAGGTCCAG CGATTTGATG GATGGTATAA CAACCTCATG 
GAGCACAGAT GGGGCAGCAA AGGCTCTCGG CTGCAGCGCC TTGTTCCGGC CAGCTATGCA 
GATGGTGTGT ACCAGCCCTT GAGAGAACCC TACCTGCCTA ACCCCCGACA CCTTAGCAAC 
AGGGTCATGA GAGGTCCCGC AGGGCAGCCG TCTCTTCGGA ACCGTACAGT CCTGGGTGTC 
TTCTTCGGCT ACCACGTGCT TTCAGACCTG GTGAGTGTGG AAACACCAGG CTGCCCCGCA 
GAGTTCCTCA ACATTTACAT CCCACGTGGG GACCCAGTGT TTGACCCTGA CAAGCGCGGG 
AACGTGGTGC TGCCCTTTCA GAGGAGCCGC TGGGACCGCA GCACTGGACA GAGCCCTAGC 
AACCCCCGAG ACCTGACCAA CCAGGTGACT GGCTGGCTAG ATGGCAGCGC CATCTATGGC 
TCCTCTCATT CCTGGAGCGA CACTCTGAGG AGCTTCTCTG GAGGACAGCT GGCTTCTGGC 
CCTGACCCTG CTTTCCCGAG GAACTCCCAG AACTCTCTGC TCATGTGGAT GGCACCAGAC 
CCCGCCACGG GGCAGGGCGG GCCACAGGGG CTGTATGCCT TCGGGGCCCA GCGCGGGAAC 
AGGGAGCCCT TTCTGCAGGC ACTGGGCTTG TTGTGGTTTC GATACCACAA CCTGTGTGCC 
AAGAGGCTGG CGCAGGAGCA CCCACACTGG GGGGATGAGG AGCTGTTCCA GCATGCTCGC 
AAGAGGGTCA TTGCCACTTA CCAGAACATT GCGATGTATG AGTGGCTGCC CAGCTTCCTG 
AAGCAAACGC CCCCAGAGTA TCCAGGATAC CATCCATTTC TGGACCCCAG CATCTCCCCA 
GAGTTCGTGG TGGCCTCAGA GCAGTTCCTC TCTACCATGG TGCCCCCTGG GGTCTACATG 
AGGAATGCCA GTTGCCACTT CCAGGGGATT GCCAATCGTA ACTCAAGTGT CTCTGGAGCT 
CTCCGGGTTT GCAACAGCTA CTGGAGTCGA GAGAACCCCA AGCTACAAAG GGCTGAAGAT 
GTGGATGCAT TGCTGCTGGG CATGGCCTCC CAGATTGCTG AGAGAGAGGA CCACCTAGTC 
GTTGAGGATG TGCAAGATTT TTGGCCCGGA CCACTGAAGT TTTCCCGTAC AGACTACCTG 
GCCAGCTGCC TGCAGAGGGG CCGGGATCTA GGCCTACCTT CATACACCAA AGCCAGGGAG 
GCACTGGGCC TGCCTCCTGT TTCCCACTGG CAGGACATCA ACCCTGCACT CTCGAGGAGC 
AATGGCACTG TGCTGGAGGC CACGGCTGCC CTGTACAATC AGGATCTGTC CCGGCTGGAG 
TTACTTGCTG GGGGGCTTCT GGAGAGCCAC GGAGACCCTG GACCCCTTTT CAGTGCTATT 
GTCCTTGACC AGTTTGTCAG GCTACGAGAT GGTGACCGCT ATTGGTTTGA AAACAACAGA 
AATGGATTGT TCTCTAAGGA AGAGATTGCA GAGATCCGAA ACACTTCCCT ACGGGATATT 
CTAGTGGCTG TCACCAACGT GGACCCCAGT GCCCTACAGC CCAGTGTCTT CTTTTGGCTT 
GCAGGAGACC CCTGTCCACA GCCAAGCCAG CTCAGCACCC AGGGCCTGCC AGCCTGTGCC 
CCCCTCTTCG TTCGGGACTA TTTCAAGGGG AGTGGATTTG GCTTCGGACT CACCATTGGG 
ACCCTTTGCT GCTTCCCCTT AGTCAGCCTC CTCAGTGCCT GGATTGTTGC CCGGCTTCGG 
ATGAGGAATT TCAAGAGGCT CCAGAGACAA GACCGCCAGA GCATCATGTG CGAGAAGCTT 
GTAGGGGGAG TGGAAGCTTT GGAGTGGCAG GGCCGCAAGG AACCCTGTAG GCCAGTGCTT 
GTGCACTTAC AGCCTGGACA GATCCGAGTC GTGGATGGCA GGCTCACTGT GCTCCGTACC 
ATCCAGCTGC GGCCCCCACA GCAGGTCAAC CTCATCCTGT CCAGCAACCG TGGACGCCGC 
ACCCTGCTGC TCAAGATCCC CAAGGAGTAC GACCTGGTGC TGTTGTTTAA CATGGAGGAG 
GAACGGCAGG CACTGGTGGA AAACATCAGG GCAGCTCTGA AGGAGAATGG ACTGAGCTTC 
CAGGAGTGGG AGCTGAGGGA GCAGGAGCTG ATGAGGGCAG CAGTGACCAG GCAACAGCGG 
GGTCACCTCC TGGAGACTTT TTTCAGGCAC CTTTTCTCCC AGGTGTTAGA CATCAATCAA 
GCAGATGCAG GGACTCTGCC ACTGGACTCT TCGACAAAAG TGCGTGAGGC TCTGACCTGC 
GAGCTGAGCA GAGCTGAGTT TGCGGACTCC CTAGGCCTCA AGCCCCAGGA TATGTTTGTG 
GAGTCCATGT TTTCTCTGGC CGACAAGGAT GGCAATGGCT ACCTGTCCTT CCGGGAGTTC 
CTGGACATCC TGGTGGTCTT CATGAAAGGC TCCCCAGAGG AGAAGTCTCG CCTCATGTTC 
CGAATGTATG ACTTTGACGG GAATGGTCTC ATCTCTAAGG ATGAGTTCAT TAGGATGCTA 
AGGTCCTTCA TCGAGATCTC CAACAACTGC CTGTCCAAGG ACCAGCTGGC TGAGGTGGTG 
GAGTCCATGT TCTGGGAGTC GGGCTTCCAG GACAAGGAGG AGCTGACCTG GGAGGACTTC 
CATTTCATGC TGCGCGACCA CGACAGCGAT CTCCGATTCA CACAGCTCTG TGTCAAAGGG 
GTGGAAGTGC CGGAAGTGAT CAAGAACCTC TGCCGGAGAG CCTCCTACAT CAGCCAGGAG 
AAGATCTGCC CTTCACCTAG AATGAGCGCC CATTGTGCCC GAAACAATAC GAAGACAGCG 
TCATCCCCAC AGAGACTGCA GTGCCCCGTG GACACGGACC CTCCTCAAGA GATTCGACGG 
AGGTTTGGCA AAAAGGTAAC TTCATTCCAG CCCTTACTGT TCACTGAGGC GCACCGAGAG 
AAGTTTCAAC GCAGCCGCCG CCACCAAACC GTGCAGCAGT TCAAGCGCTT CATTGAGAAC 
TACAGGCGCC ACATTGGCTG TGTGGCAGTG TTCTACACCA TCACTGGGGC GCTCTTCCTG 
GAGAGAGCCT ACTACTATGC GTTTGCCGCG CACCACAGCG GCATCACCGA TACTACCCGT 
GTGGGCATCA TCCTGTCCCG AGGCACGGCG GCCAGCATCT CCTTCATGTT TTCCTACATT 
TTGCTCACTA TGTGCCGCAA CCTCATCACC TTCCTGCGGG AGACCTTCCT CAACCGCTAC 
ATTCCCTTTG ATGCCGCTGT GGACTTCCAC CGCTTCATCG CCTCCACAGC CATCATCCTT 
ACAGTCTTAC ACAGTGCTGG CCACGTAGTG AATGTGTACC TGTTCTCCAT CAGCCCCCTC 
AGTGTCCTCT CTTGCCTCTT CCCTGACCTC TTCCACGATG ACGGGTCGGA GTTCCCTCAG 
AAGTATTACT GGTGGTTCTT CCAGACTGTG CCAGGTCTCA CTGGGGTCCT GCTGCTCCTG 
GCCCTGGCCA TCATGTATGT CTTCGCTTCC CACCACTTCC GCCGCCGCAG TTTCCGGGGC 
TTCTGGCTGA CCCACCACCT CTACATTTTT CTCTACATCC TGCTCATCAT CCATGGCAGC 
TTTGCTCTGA TCCAGATGCC CCGATTCCAC ATCTTCTTCC TGGTCCCCGC CATTATCTAT 
GTGGGGGACA AGCTGGTGAG CCTGAGCCGG AAGAAGGTGG AGATCAGCGT GGTGAAGGCT 
GAGCTGCTGC CTTCAGGAGT GACCCACCTG CGGTTCCAGA GGCCCCAGGG CTTTGAGTAT 
AAGTCAGGGC AGTGGGTTCG AATTGCATGC CTGGCTCTGG GAACCACCGA GTACCACCCT 
TTCACACTGA CTTCTGCACC CCACGAGGAC ACACTCAGCC TGCACATCCG GGCAGCTGGA 
CCCTGGACCA CCCGCCTCAG GGAGATCTAC TCACCCCCAA CGGGTGACAC CTGTGCCAGA 
TACCCAAAGC TGTACCTCGA TGGACCATTT GGAGAAGGCC ACCAGGAGTG GCATAAATTT 
GAGGTGTCAG TACTAGTGGG AGCTGGAATT GGGGTCACCC CCTTTGCCTC CATCCTCAAA 
GACCTGGTTT TCAAGTCATC AGTCAGCTGC CAAGTGTTCT GTAAGAAGAT CTACTTCATC 
TGGGTGACAA GGACTCAGCG GCAGTTTGAG TGGCTGGCTG ACATCATCCG GGAAGTTGAG 
GAGAATGACA GCCGGGACCT GGTGTCTGTG CACATCTATA TCACTCAGCT GGCTGAGAAG 
TTTGACCTCA GGACCACCAT GCTGTACATC TGTGAGAGGC ACTTCCAGAA GGTGCTGAAC 
AGGAGTCTGT TCACGGGCCT GCGCTCTGTC ACCCACTTTG GTCGCCCTCC CTTTGAGCCC 
TTTTTCAACT CTCTGCAGGA GGTCCACCCC CAAGTGCGAA AGATTGGAGT ATTTAGCTGT 
GGTCCCCCTG GCATGACCAA GAACGTGGAG AAGGCCTGTC AGCTCATCAA CAAGCAGGAT 
AGGACTCACT TCTCTCACCA TTATGAGAAC TTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The type of DUOX-dependent ROS production is dictated by defined sequences in DUOXA.
Experimental cell research318(18)2353-64(2012 Nov)
Hoste C,Dumont JE,Miot F,De Deken X

Mammalian numb-interacting protein 1/dual oxidase maturation factor 1 directs neuronal fate in stem cells.
The Journal of biological chemistry285(23)17974-85(2010 Jun)
Kennedy KA,Ostrakhovitch EA,Sandiford SD,Dayarathna T,Xie X,Waese EY,Chang WY,Feng Q,Skerjanc IS,Stanford WL,Li SS

Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells.
Journal of cell science122(Pt 8)1238-47(2009 Apr)
Luxen S,Noack D,Frausto M,Davanture S,Torbett BE,Knaus UG

Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium.
FEBS letters579(21)4911-7(2005 Aug)
Harper RW,Xu C,Eiserich JP,Chen Y,Kao CY,Thai P,Setiadi H,Wu R

Structural and functional characterization of the two human ThOX/Duox genes and their 5'-flanking regions.
Molecular and cellular endocrinology214(1-2)53-62(2004 Feb)
Pachucki J,Wang D,Christophe D,Miot F

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Duox1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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