Osbpl1a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Osbpl1a
Entrez Gene ID	259221
Full Name	oxysterol binding protein-like 1A
General protein information	Preferred Names oxysterol binding protein-like 1A Names oxysterol-binding protein-related protein 1 ORP-1 OSBP-related protein 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 18 Map Location: 18p13
Summary	human homolog is a member of the family of eukaryotic intracellular lipid receptors and may be involved in vesicle transport [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_172023.1	NP_742020.1	oxysterol-binding protein-related protein 1

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007687	XP_308184.4
Homo sapiens (human)	OSBPL1A	NP_542164.2
Pan troglodytes (chimpanzee)	OSBPL1A	XP_523889.2
Canis lupus familiaris (dog)	OSBPL1A	XP_005623056.1
Mus musculus (house mouse)	Osbpl1a	NP_997413.2
Macaca mulatta (Rhesus monkey)	OSBPL1A	XP_002800931.1
Danio rerio (zebrafish)	osbpl1a	XP_005161780.1
Gallus gallus (chicken)	OSBPL1A	XP_419165.2
Rattus norvegicus (Norway rat)	Osbpl1a	NP_742020.1
Drosophila melanogaster (fruit fly)	CG3860	NP_611865.1
Xenopus tropicalis (tropical clawed frog)	osbpl1a	NP_001106420.1
Bos taurus (cattle)	OSBPL1A	XP_002697769.1

Gene Ontology
Bibliography

Related articles in PubMed

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)

The mammalian oxysterol-binding protein-related proteins (ORPs) bind 25-hydroxycholesterol in an evolutionarily conserved pocket.
Suchanek M, Hynynen R, Wohlfahrt G, Lehto M, Johansson M, Saarinen H, Radzikowska A, Thiele C, Olkkonen VM
The Biochemical journal405(3)473-80(2007 Aug)

The oxysterol-binding protein homologue ORP1L interacts with Rab7 and alters functional properties of late endocytic compartments.
Johansson M, Lehto M, Tanhuanpää K, Cover TL, Olkkonen VM
Molecular biology of the cell16(12)5480-92(2005 Dec)

Structural basis of FFAT motif-mediated ER targeting.
Kaiser SE, Brickner JH, Reilein AR, Fenn TD, Walter P, Brunger AT
Structure (London, England : 1993)13(7)1035-45(2005 Jul)

Novel members of the human oxysterol-binding protein family bind phospholipids and regulate vesicle transport.
Xu Y, Liu Y, Ridgway ND, McMaster CR
The Journal of biological chemistry276(21)18407-14(2001 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Osbpl1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Osbpl1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02836	NM_172023.1 Latest version!	Rattus norvegicus oxysterol binding protein-like 1A (Osbpl1a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Osbpl1a ( NM_172023.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_742020.1 Rattus norvegicus oxysterol binding protein-like 1A (Osbpl1a), mRNA.

Price & Availability↑

CloneID	ORa02836
Clone ID Related Accession (Same CDS sequence)	NM_172023.1
Accession Version	NM_172023.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2853bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1541779200000
Organism	Rattus norvegicus(Norway rat)
Product	oxysterol-binding protein-related protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB089316.1. ##Evidence-Data-START## Transcript exon combination :: AB089316.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGAACACAG AAGCCGAGCA GCAGCTTCTC CATCACGCCA GGAATGGCAA TGCTGAAGAA 
GTGAGGAAGC TGCTGGAAGC CATGGCGCGG GCTGAAGTGG TCGCTGACAT TGACTGTAAA 
GGAAGAAGTA AGTCTAACTT GGGCTGGACA CCTCTTCATC TGGCATGCTA TTTTGGACAC 
AAACAAGTGG TCCAGGATCT GTTGAAGGCT GGTGCCAAAG TGAACATGTT AAATGACATG 
GGGGACACGC CGCTGCACCG AGCTGCCTTC ACAGGACGAA AGGAGCTAGT AATGCTTCTT 
TTAGAATATA ATGCTGACAC TACTGTCGTA AATGGAAGTG GACAGACAGC AAAAGAAGCC 
ACCCATGACA AAGAAATCAG ACAAATGCTT GAAGCTGTGG AAAGGACTCA ACAAAGAAAG 
CTTGAAGAAT TGCTTCTAGG AGCAGCTAGA GAAGGAAGAA CAGCTGAAGT GTCAGCTCTG 
CTCAGCAGGC CCAATCCTCC TGATGTGAAC TGCTCAGATC AGTTAGGAAA TACTCCCTTG 
CACTGTGCAG CCTACCGGGC CCACAAGCAG TGTGTCTTAA AGCTTCTGAG AAGTGGAGCT 
GACCCCAGCC TGAAGAACAA GAACGATCAG AAACCTCTTG ACCTTGCCCA TGGCACTGAA 
ATGAAACATA TCCTTGTTGG TAATAAGGTT GTCCACAAAG CCCTGAAACG CTTTGAAGGC 
CCTCTCTGGA AGAGTTCAAG ATTTTTTGGC TGGAAGTTAT TCTGGGTAGT GTTAGAACAC 
GGCGTCCTTT CCTGGTACAG GAAGCAGCCT GATGCAGTCC ATAATTCTTA CCGCCAAGGA 
TGCAAACACC TGACTCAAGC GGTGTGCACG GTGAAACCTA CAGATGGCTG CCTCTTCTCT 
GTCCGATGCT TTGATGACAC CGTTCATGGC TTTCGGGTTC CTAAGAACAG CCTACAGCAA 
TCGAGAGAGA AGTGGCTGGA AGCAATTGAA GAACATTCTG CATACAGCAC TCACTACTGC 
TCCCAGGATC AGGTGACTGA TGATGAAGAG GAAGATGTAG CTTCTGCCAT GGACCTGAAG 
GAGTCCTTAG CGAGAGCACA AACATGTCAA CAGAGACTAG ATAGGGAAAT TTACAACTTT 
CTCAAAATGA TTAAGGAGTG CGATGTGGCC AAAGATATGC TTCCATCATT TCTTCAGAAA 
GCTGACGTGC TCTCCGAAGC TTCTAGAGAG ACTTGTGTGG CGCTGAGTGA CTGTCTTAAT 
CTCTTCACTA AACAGGAAGG GGTAAGGAAT TTTAAATTGG AACAGGAGCA AGAAAAAAAC 
AAAATTTTGT CAGAAGCGCT GGAGACTTTA GCCACTGAGC ATCATGAACT AGAACGATCC 
CTGGTTGAAG GATCTCCGCC TGTCAGCATC CTTAGTGAGG ACGAGTTCTA TGATGCACTG 
TCAGGGTCCG AGTCCGAGGG GTCGCTGACT TGTCTGGAAG CTGTGACAGC ACGCGCCTTT 
GAAGAGAACG AAGTGCCTGC GAACAGCGGG AAGCACAGAA TGTCCGAAGG GAAGGACTGT 
GGCGGAGGAG ATGCGCTCTC CAACGGCATT AAAAAGCACA GAACAAGCCT GCCATCACCC 
ATGTTCTCCA GAAATGACTT CAGCATCTGG AGCATCCTCA GGAAATGCAT TGGGATGGAA 
CTGTCCAAGA TCACAATGCC AGTCATCTTT AATGAGCCTC TGAGCTTTCT GCAGCGGCTG 
ACTGAGTACA TGGAGCACAC TTACCTCATC CACAAAGCCA GCTCATTCTC TGATCCTGTG 
GAAAGGATGC AGTGTGTGGC TGCATTTGCT GTGTCTGCCG TTGCTTCTCA GTGGGAGCGC 
ACTGGGAAAC CCTTCAACCC ACTTCTGGGA GAGACTTACG AATTAGTTCG AGATGACCTT 
GGATTTAGGC TCATCTCAGA GCAGGTCAGC CACCACCCCC CCATCAGTGC ATTCCATGCA 
GAAGGACTCA ACAACGATTT CATCTTCCAT GGCTCAATTT ACCCCAAGCT GAAGTTCTGG 
GGCAAGAGTG TAGAAGCAGA ACCTAAAGGG ACCATCACCT TGGAGCTTTT AGAACACAAC 
GAAGCATACA CATGGACAAA CCCCACCTGC TGTGTGCATA ACATCATCGT GGGCAAACTC 
TGGATCGAAC AGTATGGCAA TGTGGAAATC ATAAACCACA AGACTGGGGA CAAGTGTGTG 
TTGAATTTTA AGCCATGTGG TCTTTTTGGC AAGGAATTAC ACAAAGTTGA AGGCTACATA 
CAAGATAAAA GCAAAAAGAA ACTCTGTGCT CTCTACGGGA AGTGGACCGA GTGCTTGTAC 
AGTGTAGACC CTGCCACTTT TGACGCTTAC AAAAAAAACG ATAAGAAAAA CACAGAAGAG 
AAGAAGACCA GCAAACAGGC AAGCACATCT GAGGAGTCTG ACGAAATGCC AGTGCCGGAC 
TCTGAGAGCG TATTTGTTAT TCCTGGCAGT GCGCTCCTGT GGCGGATAGC CCCGCGGCCT 
CCCAACTCTG CTCAGATGTA TAATTTTACC AGCTTTGCCA TGGTCTTGAA TGAGGTAGAC 
AAGGAGATGG AGACCGTGAT TCCCAAGACT GACTGCAGGC TGCGGCCTGA CATCAGAGCC 
ATGGAGAACG GAGAGATAGA TCAAGCTAGT GAAGAAAAAA AACGACTCGA GGAAAAACAA 
AGAGCAGCCC GCAAAAACAG GTCCAAGTCA GAAGAGGACT GGAAGACAAG GTGGTTTCAT 
CAAGGCCCTA ACCCCTACAG TGGAGCACAG GACTGGATTT ATTCTGGCAG CTACTGGGAC 
AGAAACTACT TCAATTTGCC TGATATTTAT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_742020.1
CDS	175..3027
Translation	MNTEAEQQLLHHARNGNAEEVRKLLEAMARAEVVADIDCKGRSKSNLGWTPLHLACYFGHKQVVQDLLKAGAKVNMLNDMGDTPLHRAAFTGRKELVMLLLEYNADTTVVNGSGQTAKEATHDKEIRQMLEAVERTQQRKLEELLLGAAREGRTAEVSALLSRPNPPDVNCSDQLGNTPLHCAAYRAHKQCVLKLLRSGADPSLKNKNDQKPLDLAHGTEMKHILVGNKVVHKALKRFEGPLWKSSRFFGWKLFWVVLEHGVLSWYRKQPDAVHNSYRQGCKHLTQAVCTVKPTDGCLFSVRCFDDTVHGFRVPKNSLQQSREKWLEAIEEHSAYSTHYCSQDQVTDDEEEDVASAMDLKESLARAQTCQQRLDREIYNFLKMIKECDVAKDMLPSFLQKADVLSEASRETCVALSDCLNLFTKQEGVRNFKLEQEQEKNKILSEALETLATEHHELERSLVEGSPPVSILSEDEFYDALSGSESEGSLTCLEAVTARAFEENEVPANSGKHRMSEGKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSFSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKTSKQASTSEESDEMPVPDSESVFVIPGSALLWRIAPRPPNSAQMYNFTSFAMVLNEVDKEMETVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYSGAQDWIYSGSYWDRNYFNLPDIY

Target ORF information:

RefSeq Version	NM_172023.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus oxysterol binding protein-like 1A (Osbpl1a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172023.1

ORF Insert Sequence:

ATGAACACAG AAGCCGAGCA GCAGCTTCTC CATCACGCCA GGAATGGCAA TGCTGAAGAA 
GTGAGGAAGC TGCTGGAAGC CATGGCGCGG GCTGAAGTGG TCGCTGACAT TGACTGTAAA 
GGAAGAAGTA AGTCTAACTT GGGCTGGACA CCTCTTCATC TGGCATGCTA TTTTGGACAC 
AAACAAGTGG TCCAGGATCT GTTGAAGGCT GGTGCCAAAG TGAACATGTT AAATGACATG 
GGGGACACGC CGCTGCACCG AGCTGCCTTC ACAGGACGAA AGGAGCTAGT AATGCTTCTT 
TTAGAATATA ATGCTGACAC TACTGTCGTA AATGGAAGTG GACAGACAGC AAAAGAAGCC 
ACCCATGACA AAGAAATCAG ACAAATGCTT GAAGCTGTGG AAAGGACTCA ACAAAGAAAG 
CTTGAAGAAT TGCTTCTAGG AGCAGCTAGA GAAGGAAGAA CAGCTGAAGT GTCAGCTCTG 
CTCAGCAGGC CCAATCCTCC TGATGTGAAC TGCTCAGATC AGTTAGGAAA TACTCCCTTG 
CACTGTGCAG CCTACCGGGC CCACAAGCAG TGTGTCTTAA AGCTTCTGAG AAGTGGAGCT 
GACCCCAGCC TGAAGAACAA GAACGATCAG AAACCTCTTG ACCTTGCCCA TGGCACTGAA 
ATGAAACATA TCCTTGTTGG TAATAAGGTT GTCCACAAAG CCCTGAAACG CTTTGAAGGC 
CCTCTCTGGA AGAGTTCAAG ATTTTTTGGC TGGAAGTTAT TCTGGGTAGT GTTAGAACAC 
GGCGTCCTTT CCTGGTACAG GAAGCAGCCT GATGCAGTCC ATAATTCTTA CCGCCAAGGA 
TGCAAACACC TGACTCAAGC GGTGTGCACG GTGAAACCTA CAGATGGCTG CCTCTTCTCT 
GTCCGATGCT TTGATGACAC CGTTCATGGC TTTCGGGTTC CTAAGAACAG CCTACAGCAA 
TCGAGAGAGA AGTGGCTGGA AGCAATTGAA GAACATTCTG CATACAGCAC TCACTACTGC 
TCCCAGGATC AGGTGACTGA TGATGAAGAG GAAGATGTAG CTTCTGCCAT GGACCTGAAG 
GAGTCCTTAG CGAGAGCACA AACATGTCAA CAGAGACTAG ATAGGGAAAT TTACAACTTT 
CTCAAAATGA TTAAGGAGTG CGATGTGGCC AAAGATATGC TTCCATCATT TCTTCAGAAA 
GCTGACGTGC TCTCCGAAGC TTCTAGAGAG ACTTGTGTGG CGCTGAGTGA CTGTCTTAAT 
CTCTTCACTA AACAGGAAGG GGTAAGGAAT TTTAAATTGG AACAGGAGCA AGAAAAAAAC 
AAAATTTTGT CAGAAGCGCT GGAGACTTTA GCCACTGAGC ATCATGAACT AGAACGATCC 
CTGGTTGAAG GATCTCCGCC TGTCAGCATC CTTAGTGAGG ACGAGTTCTA TGATGCACTG 
TCAGGGTCCG AGTCCGAGGG GTCGCTGACT TGTCTGGAAG CTGTGACAGC ACGCGCCTTT 
GAAGAGAACG AAGTGCCTGC GAACAGCGGG AAGCACAGAA TGTCCGAAGG GAAGGACTGT 
GGCGGAGGAG ATGCGCTCTC CAACGGCATT AAAAAGCACA GAACAAGCCT GCCATCACCC 
ATGTTCTCCA GAAATGACTT CAGCATCTGG AGCATCCTCA GGAAATGCAT TGGGATGGAA 
CTGTCCAAGA TCACAATGCC AGTCATCTTT AATGAGCCTC TGAGCTTTCT GCAGCGGCTG 
ACTGAGTACA TGGAGCACAC TTACCTCATC CACAAAGCCA GCTCATTCTC TGATCCTGTG 
GAAAGGATGC AGTGTGTGGC TGCATTTGCT GTGTCTGCCG TTGCTTCTCA GTGGGAGCGC 
ACTGGGAAAC CCTTCAACCC ACTTCTGGGA GAGACTTACG AATTAGTTCG AGATGACCTT 
GGATTTAGGC TCATCTCAGA GCAGGTCAGC CACCACCCCC CCATCAGTGC ATTCCATGCA 
GAAGGACTCA ACAACGATTT CATCTTCCAT GGCTCAATTT ACCCCAAGCT GAAGTTCTGG 
GGCAAGAGTG TAGAAGCAGA ACCTAAAGGG ACCATCACCT TGGAGCTTTT AGAACACAAC 
GAAGCATACA CATGGACAAA CCCCACCTGC TGTGTGCATA ACATCATCGT GGGCAAACTC 
TGGATCGAAC AGTATGGCAA TGTGGAAATC ATAAACCACA AGACTGGGGA CAAGTGTGTG 
TTGAATTTTA AGCCATGTGG TCTTTTTGGC AAGGAATTAC ACAAAGTTGA AGGCTACATA 
CAAGATAAAA GCAAAAAGAA ACTCTGTGCT CTCTACGGGA AGTGGACCGA GTGCTTGTAC 
AGTGTAGACC CTGCCACTTT TGACGCTTAC AAAAAAAACG ATAAGAAAAA CACAGAAGAG 
AAGAAGACCA GCAAACAGGC AAGCACATCT GAGGAGTCTG ACGAAATGCC AGTGCCGGAC 
TCTGAGAGCG TATTTGTTAT TCCTGGCAGT GCGCTCCTGT GGCGGATAGC CCCGCGGCCT 
CCCAACTCTG CTCAGATGTA TAATTTTACC AGCTTTGCCA TGGTCTTGAA TGAGGTAGAC 
AAGGAGATGG AGACCGTGAT TCCCAAGACT GACTGCAGGC TGCGGCCTGA CATCAGAGCC 
ATGGAGAACG GAGAGATAGA TCAAGCTAGT GAAGAAAAAA AACGACTCGA GGAAAAACAA 
AGAGCAGCCC GCAAAAACAG GTCCAAGTCA GAAGAGGACT GGAAGACAAG GTGGTTTCAT 
CAAGGCCCTA ACCCCTACAG TGGAGCACAG GACTGGATTT ATTCTGGCAG CTACTGGGAC 
AGAAACTACT TCAATTTGCC TGATATTTAT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)
Gonzales PA,Pisitkun T,Hoffert JD,Tchapyjnikov D,Star RA,Kleta R,Wang NS,Knepper MA

The mammalian oxysterol-binding protein-related proteins (ORPs) bind 25-hydroxycholesterol in an evolutionarily conserved pocket.
The Biochemical journal405(3)473-80(2007 Aug)
Suchanek M,Hynynen R,Wohlfahrt G,Lehto M,Johansson M,Saarinen H,Radzikowska A,Thiele C,Olkkonen VM

The oxysterol-binding protein homologue ORP1L interacts with Rab7 and alters functional properties of late endocytic compartments.
Molecular biology of the cell16(12)5480-92(2005 Dec)
Johansson M,Lehto M,Tanhuanpää K,Cover TL,Olkkonen VM

Structural basis of FFAT motif-mediated ER targeting.
Structure (London, England : 1993)13(7)1035-45(2005 Jul)
Kaiser SE,Brickner JH,Reilein AR,Fenn TD,Walter P,Brunger AT

Novel members of the human oxysterol-binding protein family bind phospholipids and regulate vesicle transport.
The Journal of biological chemistry276(21)18407-14(2001 May)
Xu Y,Liu Y,Ridgway ND,McMaster CR

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Osbpl1a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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